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https://www.readbyqxmd.com/read/29729889/the-inflammatory-state-of-adipose-tissue-is-not-affected-by-the-anti-inflammatory-response-of-the-a2a-adenosine-system-and-mir-221-pten
#1
J D Cortés-Garcia, M Briones-Espinoza, M Vega-Cárdenas, V M Ruíz-Rodríguez, A Mendez-Mancilla, Arturo E Gómez-Otero, J M Vargas Morales, M H García-Hernández, D P Portales-Pérez
Obesity is a chronic inflammatory state with cytokines, adipokines, and miRNAs. The A2a-adenosine system decreases activation and cytokine release in immune cells. MiR-221 is upregulated in carcinogenesis and inflammatory processes, where its targets PTEN and ETS-1, negatively regulates the Akt pathway and induces the release of pro-inflammatory cytokines, respectively. However, the roles of the A2a-adenosine system and miR-221 in adipose tissue are unknown. The aim of this work was to evaluate the A2a-adenosine and miRNA pathways as immune modulators in adipose tissue...
May 3, 2018: International Journal of Biochemistry & Cell Biology
https://www.readbyqxmd.com/read/29718290/a-longitudinal-study-of-commonly-used-admissions-measures-and-disenrollment-from-medical-school-and-graduate-medical-education-probation-or-termination-from-training
#2
Ting Dong, William R Gilliland, David Cruess, Jeffrey Hutchinson, Lisa Morres, Jerri Curtis, Gail-Selina Hewitt-Clarke, Steven J Durning
Introduction: This is an empirical study to better understand commonly used medical school admission measures and disenrollment decisions during undergraduate medical education as well as graduate medical education (GME) probation or termination decisions. Materials and Methods: Based on the data of USUHS medical students matriculating between 1998 and 2011 (N = 2,460), we compared medical school graduates and those disenrolled from medical school on MCAT scores, undergraduate BCPM (Biology, Chemistry, Physics, Math) GPA, and undergraduate overall GPA...
April 27, 2018: Military Medicine
https://www.readbyqxmd.com/read/29660575/development-and-implementation-of-a-competency-based-clinical-evaluation-tool-for-midwifery-education
#3
Kate Woeber
BACKGROUND: The learning goals and evaluation strategies of competency-based midwifery programs must be explicit and well-defined. In the US, didactic learning is evaluated through a standardized certification examination, but standardized clinical competence evaluation is lacking. DESCRIPTION OF THE TOOL: The Midwifery Competency Assessment Tool (MCAT) has been adapted from the International Confederation of Midwives' (ICM) "Essential Competencies" and from the American College of Nurse-Midwives' (ACNM) "Core Competencies", with student self-evaluation based on Benner's Novice-to-Expert theory...
March 22, 2018: Midwifery
https://www.readbyqxmd.com/read/29580252/early-musculoskeletal-classroom-education-confers-little-advantage-to-medical-student-knowledge-and-competency-in-the-absence-of-clinical-experiences-a-retrospective-comparison-study
#4
Derek Khorsand, Ansab Khwaja, Gregory A Schmale
BACKGROUND: Deficiencies in medical student knowledge in musculoskeletal medicine have been well documented. To address these deficiencies, numerous curricular changes at our institution were instituted. The objective of this study was to determine whether medical students in their preclinical years benefit from early exposure to musculoskeletal medicine when compared to students exposed to musculoskeletal medicine just prior to completion of their preclinical curriculum. METHODS: United States Medical Licensing Examination (USMLE) Step 1 and 2 scores were compared for periods of time before and after institution of the new curriculum...
March 27, 2018: BMC Medical Education
https://www.readbyqxmd.com/read/29545128/factors-associated-with-surgery-clerkship-performance-and-subsequent-usmle-step-scores
#5
Ting Dong, Annesley Copeland, Matthew Gangidine, Deanna Schreiber-Gregory, E Matthew Ritter, Steven J Durning
PURPOSE: We conducted an in-depth empirical investigation to achieve a better understanding of the surgery clerkship from multiple perspectives, including the influence of clerkship sequence on performance, the relationship between self-logged work hours and performance, as well as the association between surgery clerkship performance with subsequent USMLE Step exams' scores. METHOD: The study cohort consisted of medical students graduating between 2015 and 2018 (n = 687)...
March 12, 2018: Journal of Surgical Education
https://www.readbyqxmd.com/read/29445976/an-equivalence-study-of-interview-platform-does-videoconference-technology-impact-medical-school-acceptance-rates-of-different-groups
#6
Marlene P Ballejos, Scott Oglesbee, Jennifer Hettema, Robert Sapien
Web-based interviewing may be an effective element of a medical school's larger approach to promotion of holistic review, as recommended by the Association of American Medical Colleges, by facilitating the feasibility of including rural and community physicians in the interview process. Only 10% of medical schools offer videoconference interviews to applicants and little is known about the impact of this interview modality on the admissions process. This study investigated the impact of overall acceptance rates using videoconference interviews and face-to-face interviews in the medical school selection process using an equivalence trial design...
February 14, 2018: Advances in Health Sciences Education: Theory and Practice
https://www.readbyqxmd.com/read/29432628/the-relationship-between-preclinical-grading-and-usmle-scores-in-us-allopathic-medical-schools
#7
Seungjun Kim, Paul George
BACKGROUND AND OBJECTIVES: Pass/fail preclinical grading is associated with improved student well-being. Studies do not demonstrate differences in United States Medical Licensing Examination (USMLE) scores after adopting pass/fail grading, but were conducted at unrepresentative, highly selective institutions, and average scores increased overall during the study periods. We investigated the effect of preclinical grading on USMLE scores across 96 US medical schools. METHODS: Preclinical grading systems were identified with the 2017 Association of American Medical Colleges Medical School Admissions Requirements...
February 2018: Family Medicine
https://www.readbyqxmd.com/read/29391841/relationships-of-demographic-variables-to-usmle-physician-licensing-exam-scores-a-statistical-analysis-on-five-years-of-medical-student-data
#8
Jacqueline L Gauer, J Brooks Jackson
Introduction: The purpose of this study was to determine the associations of the demographic variables of gender, state of legal residency, student age, and undergraduate major with scores on the Medical College Admissions Test (MCAT) and the United States Medical Licensing Exam (USMLE) Step 1 and Step 2 Clinical Knowledge. Methods: The researchers collected and analyzed exam scores and demographic student data from participants of five graduating classes of students at the University of Minnesota Medical School (N = 1,067)...
2018: Advances in Medical Education and Practice
https://www.readbyqxmd.com/read/29390938/comparative-values-of-medical-school-assessments-in-the-prediction-of-internship-performance
#9
Ming Lee, Michelle Vermillion
BACKGROUND: Multiple undergraduate achievements have been used for graduate admission consideration. Their relative values in the prediction of residency performance are not clear. This study compared the contributions of major undergraduate assessments to the prediction of internship performance. METHODS: Internship performance ratings of the graduates of a medical school were collected from 2012 to 2015. Hierarchical multiple regression analyses were used to examine the predictive values of undergraduate measures assessing basic and clinical sciences knowledge and clinical performances, after controlling for differences in the Medical College Admission Test (MCAT)...
February 1, 2018: Medical Teacher
https://www.readbyqxmd.com/read/29379965/association-between-undergraduate-performance-predictors-and-academic-and-clinical-performance-of-osteopathic-medical-students
#10
Farshad Agahi, Mark R Speicher, Grace Cisek
Context: Medical schools use a variety of preadmission indices to select potential students. These indices generally include undergraduate grade point average (GPA), Medical College Admission Test (MCAT) scores, and preadmission interviews. Objective: To investigate whether the admission indices used by Midwestern University Arizona College of Osteopathic Medicine are associated with the academic and clinical performance of their students. Methods: Associations between the prematriculation variables of undergraduate science GPA, undergraduate total GPA, MCAT component scores, and interview scores and the academic and clinical variables of the first- and second-year medical school GPA, Comprehensive Osteopathic Medical Licensing Examination-USA (COMLEX-USA) Level 1 and Level 2-Cognitive Evaluation (CE) total and discipline scores, scores in clinical rotations for osteopathic competencies, COMLEX-USA Level 2-Performance Evaluation passage, and match status were evaluated...
February 1, 2018: Journal of the American Osteopathic Association
https://www.readbyqxmd.com/read/29353536/a-progressive-three-phase-innovation-to-medical-education-in-the-united-states
#11
Cory M Pfeifer
The practice of medicine has changed greatly over the past 100 years, yet the structure of undergraduate medical education has evolved very little. Many schools have modified their curricula to incorporate problem-based learning and organ systems-based curricula, but few schools have adequately addressed rising tuition costs. Undergraduate medical education has become cost-prohibitive for students interested in primary care. In the meanwhile, the concept of a separate dedicated intern year is outdated and mired in waste despite remaining a requirement for several hospital-based and surgical specialties...
December 2018: Medical Education Online
https://www.readbyqxmd.com/read/29340892/a-summer-prematriculation-program-to-help-students-succeed-in-medical-school
#12
Stephen D Schneid, April Apperson, Nora Laiken, Jess Mandel, Carolyn J Kelly, Katharina Brandl
Medical schools with a diverse student body face the challenge of ensuring that all students succeed academically. Many medical schools have implemented prematriculation programs to prepare students from diverse backgrounds; however, evidence on their impact is largely lacking. In this study, we analyzed participants' demographics as well as the impact of the prematriculation program on Year 1 performance. Predictive validity of the program was assessed and compared to other traditional predictors, including grade point average (GPA) and Medical College Admission Test (MCAT) scores and subscores...
January 16, 2018: Advances in Health Sciences Education: Theory and Practice
https://www.readbyqxmd.com/read/29190691/premedical-special-master-s-programs-increase-usmle-step1-scores-and-improve-residency-placements
#13
Bryan Johnson, Matthew Flemer, Sadik Khuder, Nitin Puri
The effectiveness of Special Master's Programs (SMPs) in benefiting a potential medical student's career beyond admission into an MD-program is largely unknown. This study aims to evaluate the role of SMPs, if any, in affecting the performance and outcomes of students during their medical school career. This study analyzed anonymous surveys of students and residents from the University of Toledo. The data analysis is used to evaluate a student's academic performance before, during and after medical school. Measured metrics included: MCAT Scores, undergraduate GPA, USMLE STEP 1 scores, participation in research, number of research publications, and residency placement...
2017: PloS One
https://www.readbyqxmd.com/read/29097213/mitochondrial-catalase-induces-cells-transformation-through-nucleolin-dependent-cox-2-mrna-stabilization
#14
Xin Liao, Chao Huang, Dongyun Zhang, Jingjing Wang, Jingxia Li, Honglei Jin, Chuanshu Huang
It's well documented that over-production of reactive oxygen species (ROS) causes detrimental damages to cells. While a low level of ROS, such as H2O2, functions as signaling transducer and motivates cell proliferation in both cancer and non-transformed stem cells. As a double-edged sword, the direct evidence for demonstrating the function of H2O2 in the cause of tumor is barely characterized in intact cells. In our current study, we found that targeted expression of mitochondrial catalase (mCAT), but not catalase, could significantly reduce the accumulation of H2O2 in mouse epithelial JB6 Cl41 cells, consequently led to the cell malignant transformation and anchorage-independent cell growth...
October 31, 2017: Free Radical Biology & Medicine
https://www.readbyqxmd.com/read/29095170/medical-school-applicant-characteristics-associated-with-performance-in-multiple-mini-interviews-versus-traditional-interviews-a-multi-institutional-study
#15
Mark C Henderson, Carolyn J Kelly, Erin Griffin, Theodore R Hall, Anthony Jerant, Ellena M Peterson, Julie A Rainwater, Francis J Sousa, David Wofsy, Peter Franks
PURPOSE: To examine applicant characteristics associated with multi mini-interview (MMI) or traditional interview (TI) performance at five California public medical schools. METHOD: Of the five California Longitudinal Evaluation of Admissions Practices (CA-LEAP) consortium schools, three used TIs and two used MMIs. Schools provided the following retrospective data on all 2011-2013 admissions cycle interviewees: age, gender, race/ethnicity (under-represented in medicine [UIM] or not), self-identified disadvantaged (DA) status, undergraduate GPA, Medical College Admission Test (MCAT) score, and interview score (standardized as z-score, mean = 0, SD = 1)...
October 31, 2017: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/29065019/formative-assessment-in-an-integrated-curriculum-identifying-at-risk-students-for-poor-performance-on-usmle-step-1-using-nbme-custom-exam-questions
#16
Judith M Brenner, Jeffrey B Bird, Joanne M Willey
PURPOSE: The Hofstra Northwell School of Medicine (HNSOM) uses an essay-based assessment system. Recognizing the emphasis graduate medical education places on the United States Medical Licensing Examination (USMLE) Step exams, the authors developed a method to predict students at risk for lower performance on USMLE Step 1. METHOD: Beginning with the inaugural class (2015), HNSOM administered National Board of Medical Examiners (NBME) Customized Assessment Service (CAS) examinations as formative assessment at the end of each integrated course in the first two years of medical school...
November 2017: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/29034852/comparison-of-direct-plating-and-broth-enrichment-culture-methods-for-detection-of-potential-bacterial-pathogens-in-respiratory-secretions
#17
COMPARATIVE STUDY
Ravinder Kaur, Jareth Wischmeyer, Matthew Morris, Michael E Pichichero
OBJECTIVE: We compared the recovery of potential respiratory bacterial pathogens and normal flora from nasopharyngeal specimens collected from children during health and at the onset of acute otitis media (AOM) by selective direct-plating and overnight broth-enrichment. METHODS: Overall, 3442 nasal wash (NW) samples collected from young children were analysed from a 10-year prospective study. NWs were cultured by (1) direct-plating to TSAII/5 % sheep blood agar and chocolate agar plates and (2) overnight broth-enrichment in BacT/ALERT SA-broth followed by plating...
November 2017: Journal of Medical Microbiology
https://www.readbyqxmd.com/read/28979178/association-between-the-medical-college-admission-test-scores-and-alpha-omega-alpha-medical-honors-society-membership
#18
Jacqueline L Gauer, J Brooks Jackson
INTRODUCTION: Medical schools worldwide are faced with the challenge of selecting from among many qualified applicants. One factor that might help admissions committees identify future exceptional medical students is scores on standardized entrance exams. The purpose of this study was to determine the association between scores on the most commonly used standardized medical school entrance exam in the USA, the Medical College Admission Test (MCAT), and election to the US medical honors society, Alpha Omega Alpha (AOA)...
2017: Advances in Medical Education and Practice
https://www.readbyqxmd.com/read/28953566/in-search-of-black-swans-identifying-students-at-risk-of-failing-licensing-examinations
#19
Cassandra Barber, Robert Hammond, Lorne Gula, Gary Tithecott, Saad Chahine
PURPOSE: To determine which admissions variables and curricular outcomes are predictive of being at risk of failing the Medical Council of Canada Qualifying Examination Part 1 (MCCQE1), how quickly student risk of failure can be predicted, and to what extent predictive modeling is possible and accurate in estimating future student risk. METHOD: Data from five graduating cohorts (2011-2015), Schulich School of Medicine & Dentistry, Western University, were collected and analyzed using hierarchical generalized linear models (HGLMs)...
March 2018: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/28944378/treatment-of-single-and-multiple-miller-class-i-and-iii-gingival-recessions-at-crown-restored-teeth-in-maxillary-esthetic-areas
#20
Anton Sculean, Raluca Cosgarea, Christos Katsaros, Nicole Birgit Arweiler, Richard John Miron, Herbert Deppe
OBJECTIVE: To clinically evaluate the outcomes following surgical coverage of single and multiple Miller Class I and III gingival recessions at crown-restored teeth in the esthetic area by means of the modified coronally advanced tunnel (MCAT). METHOD AND MATERIALS: Eight systemically healthy patients (5 females) with a total of 23 single or multiple maxillary Miller Class I or III gingival recessions were consecutively treated with MCAT in conjunction with a subepithelial connective tissue graft (SCTG)...
September 22, 2017: Quintessence International
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