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butylated hydroxytoluene

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https://www.readbyqxmd.com/read/28812524/biologically-important-hydrazide-containing-fused-azaisocytosines-as-antioxidant-agents
#1
Małgorzata Sztanke, Krzysztof Sztanke
OBJECTIVES: Two important classes of hydrazide-containing fused azaisocytosines were evaluated as possible antioxidants and characterised by UV spectroscopy. METHODS: 2,2-Diphenyl-1-picrylhydazyl (DPPH), nitric oxide (NO), hydrogen peroxide (H2O2) scavenging potencies and reducing power of molecules were evaluated. RESULTS: The strongest DPPH scavengers were found to be 9, showing the potency superior to that of butylated hydroxyanisole (BHA), butylated hydroxytoluene (BHT), propyl gallate (PG) and 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid (Trolox) and comparable to that of ascorbic acid (AA), and 6, revealing the antioxidant potency superior to that of BHA, BHT, PG and Trolox...
August 16, 2017: Redox Report: Communications in Free Radical Research
https://www.readbyqxmd.com/read/28772158/novel-antioxidant-bromophenols-with-acetylcholinesterase-butyrylcholinesterase-and-carbonic-anhydrase-inhibitory-actions
#2
Necla Öztaskın, Parham Taslimi, Ahmet Maraş, İlhami Gülcin, Süleyman Göksu
In this study, a series of novel bromophenols were synthesized from benzoic acids and methoxylated bromophenols. The synthesized compounds were evaluated by using different bioanalytical antioxidant assays including 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis (3-ethylbenzothiazoline-6-sulphonic acid) (ABTS(+)) radical scavenging assays. Also, reducing power of novel bromophenols were evaluated by Cu(2+)-Cu(+) reducing, Fe(3+)-Fe(2+) reducing and [Fe(3+)-(TPTZ)2](3+)-[Fe(2+)-(TPTZ)2]2+ reducing and ferrous ions (Fe(2+)) chelating abilities...
July 20, 2017: Bioorganic Chemistry
https://www.readbyqxmd.com/read/28768515/a-comparative-assessment-of-antiproliferative-properties-of-resveratrol-and-ethanol-leaf-extract-of-anogeissus-leiocarpus-dc-guill-and-perr-against-hepg2-hepatocarcinoma-cells
#3
Jeremiah Olorunjuwon Olugbami, Robert Damoiseaux, Bryan France, Esther Modupe Onibiyo, Michael Adedapo Gbadegesin, Shivani Sharma, James Kazimierz Gimzewski, Oyeronke Adunni Odunola
BACKGROUND: Epidemiological and experimental evidences have shown cancer as a leading cause of death worldwide. Although the folklore use of plants as a reliable source of health-restoring principles is well-documented, the search for more of such plants that are active against diseases, such as cancer, continues. We report here a laboratory-based evidence of the relevance of an ethanol leaf extract of Anogeissus leiocarpus (A2L) in comparison with resveratrol, a natural polyphenol, in cancer therapy...
August 2, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28768445/single-walled-carbon-nanotube-multi-walled-carbon-nanotube-and-fe2o3-nanoparticles-induced-mitochondria-mediated-apoptosis-in-melanoma-cells
#4
Parvaneh Naserzadeh, Fatemeh Ansari Esfeh, Mahboubeh Kaviani, Khadigeh Ashtari, Raheleh Kheirbakhsh, Ahmad Salimi, Jalal Pourahmad
PURPOSE: Nanomaterials (NM) exhibit novel anticancer properties. MATERIALS AND METHODS: The toxicity of three nanoparticles that are currently being produced in high tonnage including single-walled carbon nanotube (SWCNT), multi-walled carbon nanotube (MWCNT) and Fe2O3 nanoparticles, were compared with normal and melanoma cells. RESULTS: All tested nanoparticles induced selective toxicity and caspase 3 activation through mitochondria pathway in melanoma cells and mitochondria cause the generating of reactive oxygen species (ROS), mitochondrial membrane potential decline (MMP collapse), mitochondria swelling and cytochrome c release...
August 2, 2017: Cutaneous and Ocular Toxicology
https://www.readbyqxmd.com/read/28764086/graphite-nanocomposites-sensor-for-multiplex-detection-of-antioxidants-in-food
#5
Khan Loon Ng, Guan Huat Tan, Sook Mei Khor
Butylated hydroxyanisole (BHA), butylated hydroxytoluene (BHT), and tert-butylhydroquinone (TBHQ) are synthetic antioxidants used in the food industry. Herein, we describe the development of a novel graphite nanocomposite-based electrochemical sensor for the multiplex detection and measurement of BHA, BHT, and TBHQ levels in complex food samples using a linear sweep voltammetry technique. Moreover, our newly established analytical method exhibited good sensitivity, limit of detection, limit of quantitation, and selectivity...
December 15, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28763999/antioxidant-effects-of-extra-virgin-olive-oil-enriched-by-myrtle-phenolic-extracts-on-iron-mediated-lipid-peroxidation-under-intestinal-conditions-model
#6
Sofiane Dairi, Marie-Annette Carbonneau, Teresa Galeano-Diaz, Hocine Remini, Farid Dahmoune, Omar Aoun, Amine Belbahi, Céline Lauret, Jean-Paul Cristol, Khodir Madani
Chelating and free radicals scavenging activities of extra virgin olive oil (EVOO) enriched by Myrtus communis phenolic compounds (McPCs), α-tocopherol and Butylated hydroxytoluene (BHT) were evaluated using chemical assays, 2,2-diphenyl-1-picrylhydrazyl (DPPH) and Oxygen radical absorbance capacity (ORAC), and biological model as 2,2'-azobis (2-aminopropane) dihydrochloride (AAPH) or Fe(+3)/Ascorbic acid (Fe(+3)/AsA) system mediated peroxidation of l-α-phosphatidylcholine aqueous dispersions stabilized by bile salts (BS) under simulated intestinal conditions (pH 7...
December 15, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28751215/protective-effects-of-4-methylcoumarins-and-related-compounds-as-radical-scavengers-and-chain-breaking-antioxidants
#7
Vessela D Kancheva, Adriana K Slavova-Kazakova, Silvia E Angelova, Suraj K Singh, Shashwat Malhotra, Brajendra K Singh, Luciano Saso, Ashok K Prasad, Virinder S Parmar
The aim of this study is to determine, and to compare the protective effects of eight 4-methylcoumarins and four related compounds as radical scavengers and chain-breaking antioxidants. The main kinetic parameters of their radical scavenging activity (as % RSA, stoichiometry, n, and rate constants of reaction with DPPH radical, kRSA) and of chain breaking antioxidant activity (as antioxidant efficiency, PF and reactivity, ID), have been determined and discussed. The RSA study has been conducted at physiological temperature (37 °С) towards DPPH radical and the tested compounds are separated into three main groups: with strong activity (% RSA > 40%); with moderate activity (20% < % RSA > 40%) and with weak activity (% RSA < 20%)...
September 2017: Biochimie
https://www.readbyqxmd.com/read/28740307/evaluations-of-physicochemical-and-anti-oxidant-properties-of-powdered-leaves-from-lotus-shepherd-s-purse-and-goldenrod-in-restructured-duck-pork-patties
#8
Juhui Choe, Yuan H Brad Kim, Hack-Youn Kim, Cheon-Jei Kim
The objective of this study was to determine the effects of powdered leaves of lotus (LP), shepherd's purse (SP) and goldenrod (GP) on oxidation stability and quality characteristics of cooked duck/pork patties. Fresh duck tenderloin (M. pectoralis) and pork meat (M. biceps femoris, semitendinosus, and semimembranosus) were ground, formulated with LP, SP, GP or butylated hydroxytoluene (BHT), and mixed with other non-meat ingredients. The manufactured patties were cooked, packaged, and stored at 3 °C for 4 weeks...
July 2017: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/28718990/fungitoxicity-of-organic-extracts-of-ocimum-basilicum-on-growth-and-morphogenesis-of-bipolaris-species-teleomorph-cochliobolus
#9
E A Elsherbiny, N A Safwat, M M Elaasser
AIMS: This study aimed at evaluating the inhibitory effects of various organic extracts of Ocimum basilicum against some species of Bipolaris and Cochliobolus with GC-MS and HPLC analysis. METHODS AND RESULTS: The ethyl acetate extract consisted of methyl cinnamate as the most abundant component, while butylated hydroxytoluene was the major component in the methanol extract. Pyrogallol and chlorogenic acid were major phenolic compounds in the ethyl acetate and methanol extracts, respectively...
July 18, 2017: Journal of Applied Microbiology
https://www.readbyqxmd.com/read/28672060/phytochemical-and-biological-activities-of-pseudocalymma-elegans-a-false-garlic
#10
Sana Wahid, Muhammad Ali Versiani, Sajid Jahangir, Khurshid Jawaid, Maryam Shafique, Huma Khan, Shaheen Faizi
Evaluation of phytochemical constituents and antioxidant and antimicrobial activities of hexane (PELH), dichloromethane (PELDCM), ethyl acetate (PELEA) and methanolic (PELM) extracts of young leaves of P. elegans have been carried out. Moreover, extracts have also been explored for the presence of sulphur containing compounds, 1, 2-dithiolane (33), diallyl disulphide (35), 3-Vinyl-1,2-dithiacyclohex-5-ene (37), diallyl trisulphide (38) responsible for the garlic like smell of P. elegans. All the extracts were found to be antioxidant and showed potent inhibition with IC50 values 0...
July 3, 2017: Chemistry & Biodiversity
https://www.readbyqxmd.com/read/28633498/thymol-as-natural-antioxidant-additive-for-poultry-feed-oxidative-stability-improvement
#11
A Luna, R C Lema-Alba, J S Dambolena, J A Zygadlo, M C Labaque, R H Marin
Antioxidant are regularly included in poultry feed as protection from deterioration during storage. Recently the interest for the use of natural phytochemicals in animal diets has been increased. Thymol (THY) has been proven to be an effective antioxidant for extending broiler meat quality during storage with similar action to the widely used butylated hydroxytoluene (BHT). This study evaluates whether THY can also have a protective effect on the feed mash by assessing its antioxidant potential and related changes in fatty acid (FA) balance...
June 17, 2017: Poultry Science
https://www.readbyqxmd.com/read/28595453/chemical-composition-and-antioxidant-activities-of-the-essential-oil-of-hypericum-gaitii-haines-an-endemic-species-of-eastern-india
#12
Pradeep Kumar Kamila, Asit Ray, Sudipta Jena, Pradipta Kumar Mohapatra, Pratap Chandra Panda
The present study reports the chemical composition and antioxidant activities of the essential oil extracted from the leaves and tender branches of Hypericum gaitii Haines (Hypericaceae) - an endemic plant of Eastern India. On hydrodistillation, the fresh leaves and tender parts of H. gaitii yielded 0.43% (v/w) of pale yellowish essential oil. Gas chromatography mass spectrometry analysis revealed the presence of 40 compounds, which represent 96.9% of the total oil. Monoterpene hydrocarbons (79.3%) predominated followed by sesquiterpene hydrocarbons (12...
June 8, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28557337/a-reappraisal-of-the-proposed-metabolic-and-antioxidant-actions-of-butylated-hydroxytoluene-bht-in-the-liver
#13
Lorena Dos Santos Castro, Lívia Bracht, Jurandir Fernando Comar, Rosane Marina Peralta, Adelar Bracht
Butylated hydroxytoluene (BHT) was investigated for its metabolic actions in the perfused rat liver. Contrary to what is expected from an uncoupler, BHT up to 500 μM did not stimulate oxygen uptake nor did it inhibit gluconeogenesis from lactate. Transformation of fructose into glucose was also not affected by BHT; only lactate production was slightly increased at the concentration of 100 μM. The uncoupling effect of BHT in isolated mitochondria was confirmed, but only at concentrations above 10 μM; uncoupling at lower concentrations, 10(-9) to 10(-6)  M, could not be confirmed...
August 2017: Journal of Biochemical and Molecular Toxicology
https://www.readbyqxmd.com/read/28551227/simultaneous-analysis-of-tert-butylhydroquinone-tert-butylquinone-butylated-hydroxytoluene-2-tert-butyl-4-hydroxyanisole-3-tert-butyl-4-hydroxyanisole-%C3%AE-tocopherol-%C3%AE-tocopherol-and-%C3%AE-tocopherol-in-edible-oils-by-normal-phase-high-performance-liquid-chromatography
#14
Jun Li, Yanlan Bi, Shangde Sun, Dan Peng
A normal-phase high performance liquid chromatography method for the simultaneous determination of tert-butylhydroquinone, tert-butylquinone, butylated hydroxytoluene, 2-tert-butyl-4-hydroxyanisole, 3-tert-butyl-4-hydroxyanisole, α-tocopherol, γ-tocopherol, and δ-tocopherol in edible oils was investigated. A silica column was used to separate the analytes with the gradient elution. An ultraviolet-visible detector was set at dual wavelengths mode (280 and 310nm). The column temperature was 30°C. The analytes were directly extracted with methanol...
November 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28546949/properties-of-macerated-herbal-oil
#15
Fahsai Kantawong, Supawatchara Singhatong, Aomjai Srilamay, Kantarose Boonyuen, Niroot Mooti, Phenphichar Wanachantararak, Thasaneeya Kuboki
Introduction: The addition of herbs into hot sesame oil could increase the oil-pulling efficiency of sesame oil. The aim of present study was to modify the proportion of herbs and sesame oil with the addition of other ingredients including menthol, camphor, and borneol and improve the medicinal properties and the scent of the oil. Methods: Macerated herbal oil was prepared by heat extraction of five species of herbs (Zingiber cassumunar, Zingiber zerumbet, Plantago major Linn, Citrus hystrix, and Amomum biflorum) with hot sesame oil...
2017: BioImpacts: BI
https://www.readbyqxmd.com/read/28539735/pharmacognostic-specification-chlorogenic-acid-content-and-in-vitro-antioxidant-activities-of-lonicera-japonica-flowering-bud
#16
Chayanon Chaowuttikul, Chanida Palanuvej, Nijsiri Ruangrungsi
BACKGROUND: Lonicera japonica Thunb. or Japanese Honeysuckle has been widely used in traditional medicine for antipyretic. OBJECTIVE: To establish the pharmacognostic specification of L. japonica flowering bud in Thailand and to determine its chlorogenic acid content and in vitro antioxidant activities. MATERIALS AND METHODS: Dried L. japonica flowering bud from 15 various herbal drugstores throughout Thailand were investigated for pharmacognostic specification...
April 2017: Pharmacognosy Research
https://www.readbyqxmd.com/read/28539727/bioassay-guided-isolation-and-identification-of-antioxidant-flavonoids-from-cyclotrichium-origanifolium-labill-manden-and-scheng
#17
Abdussamat Guzel, Huseyin Aksit, Mahfuz Elmastas, Ramazan Erenler
BACKGROUND: Medicinal and aromatic plants play a significant role in drug discovery and development process. Flavonoids, revealing a wide spectrum of biological activities, extensively found in plants are important secondary metabolites. MATERIALS AND METHODS: Aerial parts of Cyclotrichium origanifolium were collected, dried, and boiled in water then extracted with hexane, ethyl acetate, and n-butanol. Total phenolic content, DPPH(•) scavenging activity, reducing power (FRAP) activity, and ABTS(•+) scavenging activity assays were applied for all extracts...
April 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/28515648/evaluation-of-antioxidative-activity-of-various-levels-of-ethanol-extracted-tomato-powder-and-application-to-pork-patties
#18
Hyeong Sang Kim, Koo Bok Chin
This study was performed to evaluate antioxidant activity of tomato powder extracted by various concentrations of ethanol (0, 25, 50, 75, 100%) and to evaluate the physicochemical properties and antioxidant activities of pork patties with ethanol extracted tomato (EET) powder. No differences in the contents of total of individual phenolic compounds including gallic acid and catechin, were observed among the treatments (p>0.05). Among the various concentrations, 50% and 75% EET powder showed the highest free radical scavenging and iron chelating activities (p<0...
2017: Korean Journal for Food Science of Animal Resources
https://www.readbyqxmd.com/read/28490135/polyunsaturated-lipids-and-vitamin-a-oxidation-during-cod-liver-oil-in-vitro-gastrointestinal-digestion-antioxidant-effect-of-added-bht
#19
Bárbara Nieva-Echevarría, Encarnación Goicoechea, María D Guillén
The extent of cod liver oil hydrolysis and oxidation during in vitro gastrointestinal digestion was investigated by Proton Nuclear Magnetic Resonance ((1)H NMR) and Solid Phase Microextraction-Gas Chromatography/Mass Spectrometry (SPME-GC/MS). These techniques evidenced the degradation of polyunsaturated ω-3 and ω-6 lipids and, for the first time, that of vitamin A, naturally present in cod liver oil. Cis,trans-conjugated dienes associated with hydroperoxides, as well as monoepoxides, cis,trans-2,4-alkadienals, 4-hydroperoxy- and 4-hydroxy-2-alkenals, and several vitamin A derived metabolites were generated...
October 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28482695/previously-undescribed-antioxidative-azocinyl-morpholinone-alkaloid-from-red-seaweed-gracilaria-opuntia-with-anti-cyclooxygenase-and-lipoxygenase-properties
#20
Fasina Makkar, Kajal Chakraborty
In vitro antioxidative and anti-inflammatory bioassay-guided fractionation of the methanol: ethyl acetate crude extract of the thalli of red seaweed Gracilaria opuntia collected from the Gulf of Mannar led to the isolation of a new morpholine alkaloid 3-(2-ethyl-6-((3Z,7Z)-1,2,5,6-tetrahydroazocin-5-yl)hexyl) morpholin-6-one. The substituted azocinyl morpholinone recorded significant 1,1-diphenyl-2-picryl-hydrazil free radical scavenging activities (IC50 ~ 0.086 mg/mL) compared to the commercially available antioxidants, butylated hydroxyanisole, butylated hydroxytoluene, and α-tocopherol (IC50 > 0...
May 8, 2017: Natural Product Research
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