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Post stroke pain

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https://www.readbyqxmd.com/read/28393896/effects-of-ibudilast-on-the-subjective-reinforcing-and-analgesic-effects-of-oxycodone-in-recently-detoxified-adults-with-opioid-dependence
#1
Verena E Metz, Jermaine D Jones, Jeanne Manubay, Maria Sullivan, Shanthi Mogali, Andrew Segoshi, Gabriela Madera, Kirk W Johnson, Sandra D Comer
Ibudilast, a non-selective phosphodiesterase inhibitor, is used clinically in Asia for the treatment of asthma and post-stroke dizziness. Recent preclinical studies have suggested that it also inhibits glial cell activation in rodents, and may alter opioid-mediated effects, including analgesia and withdrawal symptoms. The effects of ibudilast on the abuse potential of opioids in humans are largely unknown. The present study was designed to examine the influence of ibudilast on subjective (including drug craving), reinforcing, and analgesic effects of oxycodone in human volunteers diagnosed with opioid dependence (equivalent to moderate-severe opioid use disorder)...
April 10, 2017: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28380672/randomized-clinical-trial-of-deep-brain-stimulation-for-post-stroke-pain
#2
Scott F Lempka, Donald A Malone, Bo Hu, Kenneth B Baker, Alexandria Wyant, John Ozinga, Ela B Plow, Mayur Pandya, Cynthia S Kubu, Paul J Ford, Andre G Machado
OBJECTIVE: The experience with deep brain stimulation (DBS) for pain is largely based on uncontrolled studies targeting the somatosensory pathways, with mixed results. We hypothesized that targeting limbic neural pathways would modulate the affective sphere of pain and alleviate suffering. METHODS: We conducted a prospective, double-blinded, randomized, placebo-controlled, crossover study of DBS targeting the ventral striatum/anterior limb of the internal capsule (VS/ALIC) in 10 patients with post-stroke pain syndrome...
April 5, 2017: Annals of Neurology
https://www.readbyqxmd.com/read/28343442/effectiveness-of-neuromuscular-electrical-stimulation-for-management-of-shoulder-subluxation-post-stroke-a-systematic-review-with-meta-analysis
#3
Jae-Hyoung Lee, Lucinda L Baker, Robert E Johnson, Julie K Tilson
OBJECTIVES: To examine the effectiveness of neuromuscular electrical stimulation (NMES) for the management of shoulder subluxation after stroke including assessment of short (1 hour or less) and long (more than one hour) daily treatment duration. DATA SOURCES: MEDLINE, CENTRAL, CINAHL, WOS, KoreaMed, RISS and reference lists from inception to January 2017 Review methods: We considered randomized controlled trials that reported neuromuscular electrical stimulation for the treatment of shoulder subluxation post-stroke...
March 1, 2017: Clinical Rehabilitation
https://www.readbyqxmd.com/read/28289555/gender-differences-in-post-traumatic-stress
#4
Maria Grazia Modena, Daniele Pettorelli, Giulia Lauria, Elisa Giubertoni, Erminio Mauro, Valentina Martinotti
Acute stress can trigger cardiovascular events and disease. The earthquake is an "ideal" natural experiment for acute and chronic stress, with impact mainly on the cardiovascular system. On May 20th and 29th, 2012, two earthquakes of magnitude 5.9° to 6.4° on the Richter scale, hit the province of Modena and Reggio Emilia, an area of the north-center of Italy never considered at seismic risk. The purpose of our study was to assess whether there were gender-specific differences in stress-induced incidence of cardiovascular events and age of patients who arrived at the Emergency Departments (ED) of the three main teaching hospitals of the University of Modena and Reggio Emilia...
2017: BioResearch Open Access
https://www.readbyqxmd.com/read/28222545/effect-of-medical-complications-on-the-after-stroke-rehabilitation-outcome
#5
Barbara Janus-Laszuk, Dagmara Mirowska-Guzel, Iwona Sarzynska-Dlugosz, Anna Czlonkowska
BACKGROUND: Post-stroke rehabilitation should begin immediately and continue while improvement is seen. After stroke, patients are at risk of developing medical complications, which can hinder optimal recovery. OBJECTIVE: We aimed to determine the incidence of complications occurring during early inpatient rehabilitation and to assess their influence on patients' functionality. METHODS: For 1075 patients (585 men), we recorded neurological deficits, activities of everyday living, functionality before and after rehabilitation, and the incidence of complications...
2017: NeuroRehabilitation
https://www.readbyqxmd.com/read/28222382/corporeal-illusions-in-chronic-spinal-cord-injuries
#6
Michele Scandola, Salvatore Maria Aglioti, Renato Avesani, Gianettore Bertagnoni, Anna Marangoni, Valentina Moro
While several studies have investigated corporeal illusions in patients who have suffered from a stroke or undergone an amputation, only anecdotal or single case reports have explored this phenomenon after spinal cord injury. Here we examine various different types of bodily misperceptions in a comparatively large group of 49 people with spinal cord injury in the post-acute and chronic phases after the traumatic lesion onset. An extensive battery of questionnaires concerning a variety of body related feelings was administered and the results were correlated to the main clinical variables...
March 2017: Consciousness and Cognition
https://www.readbyqxmd.com/read/28151918/thalamic-pain-alleviated-by-stellate-ganglion-block-a-case-report
#7
Chenlong Liao, Min Yang, Pengfei Liu, Wenxiang Zhong, Wenchuan Zhang
RATIONALE: Thalamic pain is a distressing and treatment-resistant type of central post-stroke pain. Although stellate ganglion block is an established intervention used in pain management, its use in the treatment of thalamic pain has never been reported. PATIENT CONCERNS: A 66-year-old woman presented with a 3-year history of severe intermittent lancinating pain on the right side of the face and the right hand. The pain started from the ulnar side of the right forearm after a mild ischemic stroke in bilateral basal ganglia and left thalamus...
February 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28145396/a-randomized-controlled-trial-on-the-immediate-and-long-term-effects-of-arm-slings-on-shoulder-subluxation-in-stroke-patients
#8
Anke VAN Bladel, Gert Lambrecht, Kristine M Oostra, Guy Vanderstraeten, Dirk Cambier
BACKGROUND: Arm slings are often used in clinical practice to support the hemiplegic arm aiming to prevent or treat glenohumeral subluxation. Evidence supporting the corrective effect of slings on subluxation is scarce and long-term studies are lacking. AIM: To determine both the immediate and long-term effect on acromiohumeral distance using the Actimove® sling (BSN medical SA-NV, Leuven, Belgium) and Shoulderlift (V!GO, Belgium) and to determine the effect of slings on pain and passive range of motion of the shoulder in stroke patients with glenohumeral subluxation...
January 30, 2017: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/28103638/music-interventions-for-acquired-brain-injury
#9
REVIEW
Wendy L Magee, Imogen Clark, Jeanette Tamplin, Joke Bradt
BACKGROUND: Acquired brain injury (ABI) can result in impairments in motor function, language, cognition, and sensory processing, and in emotional disturbances, which can severely reduce a survivor's quality of life. Music interventions have been used in rehabilitation to stimulate brain functions involved in movement, cognition, speech, emotions, and sensory perceptions. An update of the systematic review published in 2010 was needed to gauge the efficacy of music interventions in rehabilitation for people with ABI...
January 20, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28093564/postoperative-conversion-disorder-presenting-as-inspiratory-stridor-and-hemiparesis-in-a-pediatric-patient
#10
Erik J Nelson, Jennifer Y Wu
BACKGROUND Postoperative conversion disorder is rare and has been reported. The diagnosis is usually made after all major organic causes have been ruled out. CASE REPORT We describe a case of a 13-year-old female who presented in the post-anesthesia care unit with acute-onset inspiratory stridor and unresponsiveness to verbal or painful stimuli after receiving a general anesthetic for upper endoscopy. Later in the post-anesthesia care unit, she presented with acute-onset right hemiplegia and sensory loss. She was first evaluated for causes of her stridor and unresponsiveness...
January 17, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/28029070/an-exploration-of-factors-influencing-physical-activity-levels-amongst-a-cohort-of-people-living-in-the-community-after-stroke-in-the-south-of-england
#11
Sharon Jackson, Christopher Mercer, Barbara Jennifer Singer
PURPOSE: To explore factors influencing physical activity (PA) reported by people living in rural/semi-rural communities in the south of England post-stroke, and to understand relationships between personal, interpersonal and environmental barriers and self-reported levels of PA. METHOD: A survey was mailed to patients of NHS Trusts who were identified as potential participants. Self-reported PA levels, type, and frequency of reported barriers were tabulated. Spearman's rank correlation coefficient was used to explore associations between self-reported PA level and: age, gender, level of physical function, fear of falling, beliefs regarding PA, available supports, and socioeconomic status...
December 28, 2016: Disability and Rehabilitation
https://www.readbyqxmd.com/read/27995202/a-novel-bilateral-lower-extremity-mirror-therapy-intervention-for-individuals-with-stroke
#12
Lucas D Crosby, Stephanie Marrocco, Janet Brown, Kara K Patterson
Despite improvements made in stroke rehabilitation, motor impairment and gait deficits persist at discharge. New interventions are needed. Mirror therapy has promise as one element of a rehabilitation program. The primary objectives were to 1) describe a bilateral, lower extremity mirror therapy (LE-MT) device and training protocol and 2) investigate the feasibility of LE-MT. A LE-MT device was constructed to train bilateral LE movements for 30 min, 3 times/week for 4 weeks, as an adjunct to physiotherapy in three individuals post-stroke...
December 2016: Heliyon
https://www.readbyqxmd.com/read/27977072/mechanical-pinprick-pain-in-patients-with-unilateral-spatial-neglect-the-influence-of-space-representation-on-the-perception-of-nociceptive-stimuli
#13
V Vizzari, S Barba, P Gindri, S Duca, D Giobbe, P Cerrato, G Geminiani, D M Torta
BACKGROUND: Crossing the hands over the midline can reduce the perceived intensity of nociceptive stimuli applied onto the hands. It remains unclear to what extent intact representation of peripersonal space influences this effect. Here we used the crossed-hands paradigm in patients with unilateral spatial neglect, a neuropsychological condition characterized by the inability to detect, attend and respond to contralesional (most often left) stimuli, and spared ability to process stimuli in the non-affected space...
April 2017: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/27955797/acute-esophageal-injury-and-strictures-following-corrosive-ingestions-in-a-27year-cohort
#14
Timothy Cowan, Robert Foster, Geoffrey K Isbister
PURPOSE: We aimed to determine the incidence of esophageal strictures in corrosive ingestions and potential predictors of severe injury. BASIC PROCEDURES: This was a retrospective cohort study of corrosive ingestions from a toxicology unit (1987-2013) with telephone follow-up at least 1 y post-ingestion. Clinical data and investigations were obtained from a toxicology admission database. The primary outcome was esophageal stricture. Other outcomes included in-hospital mortality, endoscopy grade and early complications...
December 6, 2016: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/27919055/associations-with-health-related-quality-of-life-after-intracerebral-haemorrhage-pooled-analysis-of-interact-studies
#15
Candice Delcourt, Danni Zheng, Xiaoying Chen, Maree Hackett, Hisatomi Arima, Jun Hata, Emma Heeley, Rustam Al-Shahi Salman, Mark Woodward, Yining Huang, Thompson Robinson, Pablo M Lavados, Richard I Lindley, Christian Stapf, Leo Davies, John Chalmers, Craig S Anderson, Shoichiro Sato
BACKGROUND AND PURPOSE: Limited data exist on health-related quality of life (HRQoL) after intracerebral haemorrhage (ICH). We aimed to determine baseline factors associated with HRQoL among participants of the pilot and main phases of the Intensive Blood Pressure Reduction in Acute Cerebral Haemorrhage Trials (INTERACT 1 and 2). METHODS: The INTERACT studies were randomised controlled trials of early intensive blood pressure (BP) lowering in patients with ICH (<6 hours) and elevated systolic BP (150-220 mm Hg)...
January 2017: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/27912744/quality-of-life-after-stroke-in-pakistan
#16
Wardah Khalid, Shafquat Rozi, Tazeen Saeed Ali, Iqbal Azam, Michael T Mullen, Saleem Illyas, Qamar Un-Nisa, Nabila Soomro, Ayeesha Kamran Kamal
BACKGROUND: There is very little information about the quality of life (QOL) of stroke survivors in LMIC countries with underdeveloped non communicable health infrastructures, who bear two thirds of the global stroke burden. METHODOLOGY: We used a sequential mix methods approach. First, a quantitative analytical cross-sectional study was conducted on 700 participants, who constituted 350 stroke survivor and their caregiver dyads. QOL of stroke survivor was assessed via Stroke Specific Quality of Life Scale (SSQOLS) whereas QOL of caregivers was assessed through RAND-36...
December 3, 2016: BMC Neurology
https://www.readbyqxmd.com/read/27906935/long-term-prednisolone-in-post-stroke-complex-regional-pain-syndrome
#17
Jayantee Kalita, Usha Misra, Ajit Kumar, Sanjeev K Bhoi
BACKGROUND: There is no study on the long-term use of prednisolone in post-stroke complex regional pain syndrome-1 (CRPS1). OBJECTIVE: To evaluate the efficacy and safety of long-term low dose prednisolone in post-stroke CRPS-I. STUDY DESIGN: Open-labeled randomized controlled trial. SETTING: Tertiary care teaching institute. METHODS: Seventy-seven out of 396 (19.4%) patients with stroke had CRPS-1 and 58 met the inclusion criteria...
November 2016: Pain Physician
https://www.readbyqxmd.com/read/27898167/nsaids-prescription-prevalence-after-a-cardiovascular-event-related-hospitalization-in-medicaid-beneficiaries-from-puerto-rico
#18
Suzette M Vélez, José J Hernández, Sasha M Davis, María G Almodóvar, José R Mercado
OBJECTIVE: Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly prescribed for pain and inflammation. NSAIDs are associated with serious adverse effects and cardiovascular (CV) risks that include myocardial infarction, stroke and heart failure. In the period of time immediately after a CV event, modification to the drug therapy regimen and lifestyle habits should be instituted to decrease morbidity and mortality. The objective of this study is to measure the prevalence of NSAIDs prescribing in the immediate 90 days after a CV-related hospitalization in Medicaid beneficiaries in Puerto Rico...
December 2016: Puerto Rico Health Sciences Journal
https://www.readbyqxmd.com/read/27881958/motor-cortex-neurostimulation-technologies-for-chronic-post-stroke-pain-implications-of-tissue-damage-on-stimulation-currents
#19
Anthony T O'Brien, Rivadavio Amorim, R Jarrett Rushmore, Uri Eden, Linda Afifi, Laura Dipietro, Timothy Wagner, Antoni Valero-Cabré
Background: Central post stroke pain (CPSP) is a highly refractory syndrome that can occur after stroke. Primary motor cortex (M1) brain stimulation using epidural brain stimulation (EBS), transcranial magnetic stimulation (TMS), and transcranial direct current stimulation (tDCS) have been explored as potential therapies for CPSP. These techniques have demonstrated variable clinical efficacy. It is hypothesized that changes in the stimulating currents that are caused by stroke-induced changes in brain tissue conductivity limit the efficacy of these techniques...
2016: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/27871449/botulinum-toxin-as-early-intervention-for-spasticity-after-stroke-or-non-progressive-brain-lesion-a-meta-analysis
#20
Raymond L Rosales, Fran Efendy, Ericka Sa Teleg, Mary Md Delos Santos, Mary Ce Rosales, Marc Ostrea, Michelle J Tanglao, Arlene R Ng
Spasticity is a functionally limiting disorder that commonly occurs following stroke or severe brain injury, and may lead to disability and pain. In tandem with neurorehabilitation, botulinum toxin type A (BoNT-A) is the recommended first-line treatment for spasticity and, to date, the majority of trials have reported BoNT-A use in patients >6months after ictus. The present meta-analysis aimed to evaluate the effects of early BoNT-A injection for post-stroke spasticity on improvements in hypertonicity, disability, function and associated pain...
December 15, 2016: Journal of the Neurological Sciences
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