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Bariatric interventions

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https://www.readbyqxmd.com/read/28906072/it-just-made-me-feel-so-desolate-patients-narratives-of-weight-gain-following-laparoscopic-insertion-of-a-gastric-band
#1
Frances Marjorie May Lloyd, Alistair Hewison, Nikolaos Efstathiou
AIMS AND OBJECTIVES: To describe the experiences of patients who have failed to maintain weight loss following the insertion of a Laparoscopic Adjustable Gastric Band (LAGB) for the treatment of morbid obesity. BACKGROUND: Obesity is a global health problem resulting in physical, psychological and economic problems, and presenting challenges for health services. Surgical intervention is an increasingly common approach to treatment, however some patients do not sustain their weight loss following bariatric surgery and little is known about people's longer-term experiences following LAGB insertion...
September 14, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28904467/post-bariatric-surgery-acute-axonal-polyneuropathy-doing-your-best-is-not-always-enough
#2
Zakia Mohammad Yasawy, Ali Hassan
Neurological complications are frequently recognized with weight reduction surgeries for morbid obesity. The spectrum of peripheral neuropathies complicating the weight loss surgery is wide, and among them, the acute axonal peripheral neuropathy resembling Guillain-Barre syndrome is rare and only less than a dozen cases are reported. We present three cases, which after bariatric surgery developed acute polyneuropathy that rapidly progressed over 4 weeks from the onset. All patients responded to aggressive parenteral Vitamin B1 and B12 replacement therapy...
July 2017: Annals of Indian Academy of Neurology
https://www.readbyqxmd.com/read/28874313/new-therapeutic-perspectives-in-non-alcoholic-steatohepatitis
#3
Javier Ampuero, Yolanda Sánchez-Torrijos, Virginia Aguilera, Francisco Bellido, Manuel Romero-Gómez
Management of non-alcoholic steatohepatitis is focused on restitution of metabolic derangement, weight loss and drugs able to improve steatosis, ballooning and fibrosis. Life-style interventions based on Mediterranean diet and increasing physical activity are the first line therapy. In patients with unsuccessful life-style intervention several drugs are under development: agonist PPAR, agonist GLP-1R and agonist FXR together with drugs focussing on inflammation, ballooning, apoptosis and fibrosis. Bariatric surgery or advanced endoscopy are reserved for morbid obese without response to life-style intervention and weighting loss drugs...
September 2, 2017: Gastroenterología y Hepatología
https://www.readbyqxmd.com/read/28873387/just-a-gut-feeling-central-nervous-effects-of-peripheral-gastrointestinal-hormones
#4
Christian L Roth, Robert Patrick Doyle
Despite greater health education, obesity remains one of the greatest health challenges currently facing the world. The prevalence of obesity among children and adolescents and the rising rates of prediabetes and diabetes are of particular concern. A deep understanding of regulatory pathways and development of new anti-obesity drugs with increased efficacy and safety are of utmost necessity. The 2 major biological players in the regulation of food intake are the gut and the brain as peptides released from the gut in response to meals convey information about the energy needs to brain centers of energy homeostasis...
2017: Endocrine Development
https://www.readbyqxmd.com/read/28870706/bariatric-surgery-in-adolescents-with-severe-obesity-review-and-state-of-the-art-in-france
#5
Régis Coutant, Natacha Bouhours-Nouet, Aurélie Donzeau, Mathilde Fauchard, Anne Decrequy, Jean Malka, Elise Riquin, Marion Beaumesnil, Agnès Sallé, Claire Briet, Philippe Topart, Françoise Schmitt
Severe obesity (body mass index>120% of BMI IOTF-30 cut off) and morbid obesity (BMI>140% of BMI IOTF-30 cut off) affect 5 to 10% of obese adolescents in France. Organic complications can be found in about 50% of these patients, and depressive symptoms in one-third of them. Finally, over 70% will suffer from adult morbid obesity associated with a marked increase in morbidity and mortality. However, the reversion of obesity strongly decreases, and may even cancels, these risks. In controlled randomized studies, lifestyle interventions have limited effectiveness on BMI in children (and none in adolescents)...
September 1, 2017: Annales D'endocrinologie
https://www.readbyqxmd.com/read/28869025/-gastric-aspiration-therapy-is-a-possible-alternative-to-treatment-of-obesity
#6
Marie Møller Christensen, Tina Jorsal, Lars Peter Skat Naver, Tina Vilsbøll, Filip Krag Knop
Aspiration therapy with AspireAssist is a novel endoscopic obesity treatment. Patients aspirate approximately 30% of an ingested meal through a draining system connected to a percutanous endoscopic gastrostomy tube. AspireAssist was recently approved by the US Food and Drug Administration, and it induces weight loss comparable to the weight loss observed after bariatric surgery, but with a lower risk of complications. Few clinical studies about the efficacy and safety of AspireAssist have been carried out and published...
August 7, 2017: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/28868615/mechanisms-of-weight-loss-and-improved-metabolism-following-bariatric-surgery
#7
REVIEW
Christopher M Mulla, Roeland J W Middelbeek, Mary-Elizabeth Patti
Bariatric surgery is increasingly recognized as one of the most effective interventions to help patients achieve significant and sustained weight loss, as well as improved metabolic and overall health. Unfortunately, the cellular and physiological mechanisms by which bariatric surgery achieves weight loss have not been fully elucidated, yet are critical to understanding the central role of the intestinal tract in whole-body metabolism and to developing novel strategies for the treatment of obesity. In this review, we provide an overview of potential mechanisms contributing to weight loss, including effects on regulation of energy balance and both central and peripheral nervous system regulation of appetite and metabolism...
September 3, 2017: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/28866649/weight-loss-for-overweight-and-obese-individuals-with-gout-a-systematic-review-of-longitudinal-studies
#8
Sabrina M Nielsen, Else M Bartels, Marius Henriksen, Eva E Wæhrens, Henrik Gudbergsen, Henning Bliddal, Arne Astrup, Filip K Knop, Loreto Carmona, William J Taylor, Jasvinder A Singh, Fernando Perez-Ruiz, Lars E Kristensen, Robin Christensen
OBJECTIVES: Weight loss is commonly recommended for gout, but the magnitude of the effect has not been evaluated in a systematic review. The aim of this systematic review was to determine benefits and harms associated with weight loss in overweight and obese patients with gout. METHODS: We searched six databases for longitudinal studies, reporting the effect of weight loss in overweight/obese gout patients. Risk of bias was assessed using the tool Risk of Bias in Non-Randomised Studies of Interventions...
September 2, 2017: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/28853051/patient-predictors-of-weight-loss-following-a-behavioral-weight-management-intervention-among-us-veterans-with-severe-obesity
#9
Luke M Funk, Janet M Grubber, Megan A McVay, Maren K Olsen, William S Yancy, Corrine I Voils
PURPOSE: Identification of patient characteristics that are associated with behavioral weight loss success among bariatric surgery candidates could inform selection of optimal bariatric surgery candidates. We examined the associations between psychosocial characteristics and weight loss in a group of Veterans with severe obesity who participated in a behavioral weight loss intervention. METHODS: The MAINTAIN trial involved a 16-week weight loss program followed by randomization among participants losing at least 4 kg to a maintenance intervention or usual care...
August 29, 2017: Eating and Weight Disorders: EWD
https://www.readbyqxmd.com/read/28840500/hypertension-in-obesity-and-the-impact-of-weight-loss
#10
REVIEW
Jordana B Cohen
PURPOSE OF REVIEW: Several interrelated mechanisms promote the development of hypertension in obesity, often contributing to end organ damage including cardiovascular disease and chronic kidney disease. RECENT FINDINGS: The treatment of hypertension in obesity is complicated by a high prevalence of resistant hypertension, as well as unpredictable hemodynamic effects of many medications. Weight loss stabilizes neurohormonal activity and causes clinically significant reductions in blood pressure...
August 24, 2017: Current Cardiology Reports
https://www.readbyqxmd.com/read/28838280/neuroendocrine-regulation-of-energy-balance-implications-on-the-development-and-surgical-treatment-of-obesity
#11
Gisele Farias, Bárbara Dal Molin Netto, Solange Cravo Bettini, Ana Raimunda Dâmaso, Alexandre Coutinho Teixeira de Freitas
INTRODUCTION: Obesity, a serious public health problem, occurs mainly when food consumption exceeds energy expenditure. Therefore, energy balance depends on the regulation of the hunger-satiety mechanism, which involves interconnection of the central nervous system and peripheral signals from the adipose tissue, pancreas and gastrointestinal tract, generating responses in short-term food intake and long-term energy balance. Increased body fat alters the gut- and adipose-tissue-derived hormone signaling, which promotes modifications in appetite-regulating hormones, decreasing satiety and increasing hunger senses...
January 1, 2017: Nutrition and Health
https://www.readbyqxmd.com/read/28832360/gastric-interventional-endoscopy
#12
Mohamed Mahmoud, Erik Holzwanger, Wahid Wassef
PURPOSE OF REVIEW: To review new advances in gastric interventional endoscopy. RECENT FINDINGS: Implementation of gastric endoscopy as a therapeutic option in obesity, gastric cancer, and gastroparesis. SUMMARY: Less invasive new gastric endoscopic procedures can potentially replace currently offered laparoscopic approaches in many fields. In this article, we will review the use of endoscopic sleeve gastroplasty as a weight loss procedure, endoscopic submucosal dissection in treatment of early gastric cancer, and gastric per-oral endoscopic myotomy in treatment of refractory gastroparesis...
August 21, 2017: Current Opinion in Gastroenterology
https://www.readbyqxmd.com/read/28831733/pre-surgical-pulmonary-rehabilitation-in-asthma-patients-undergoing-bariatric-surgery
#13
Yasemin Türk, Astrid van Huisstede, Pieter S Hiemstra, Christian Taube, Gert-Jan Braunstahl
This pilot study was performed to investigate the feasibility of pre-surgical pulmonary rehabilitation (PR) in morbidly obese patients with uncontrolled asthma, undergoing bariatric surgery. Four morbidly obese female patients with asthma participated in a 12-week PR program (exercise, diet, and psychological intervention) before undergoing bariatric surgery, and the outcomes were compared to a matched group of seven female controls (bariatric surgery only). In patients who participated in PR, asthma control and asthma quality of life improved dramatically after 3 months of PR...
August 22, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28830535/association-of-bariatric-surgery-with-risk-of-acute-care-use-for-hypertension-related-disease-in-obese-adults-population-based-self-controlled-case-series-study
#14
Yuichi J Shimada, Yusuke Tsugawa, Hiroyasu Iso, David F M Brown, Kohei Hasegawa
BACKGROUND: Hypertension carries a large societal burden. Obesity is known as a risk factor for hypertension. However, little is known as to whether weight loss interventions reduce the risk of hypertension-related adverse events, such as acute care use (emergency department [ED] visit and/or unplanned hospitalization). We used bariatric surgery as an instrument for investigating the effect of large weight reduction on the risk of acute care use for hypertension-related disease in obese adults with hypertension...
August 23, 2017: BMC Medicine
https://www.readbyqxmd.com/read/28798989/perceived-postoperative-support-differentiates-responders-from-non-responders-3%C3%A2-years-after-laparoscopic-roux-en-y-gastric-bypass
#15
Ulrike B J M Ter Braak, Chris Hinnen, Marjolein M C de Jong, Arnold van de Laar
BACKGROUND: Bariatric surgery is an effective intervention for the majority of patients with morbid obesity, but a significant minority fails to achieve substantial weight loss. In the search of possible predictors of weight loss following bariatric surgery, preoperative factors turn out to have limited predictive power. This study will examine the impact of two postoperative factors on weight loss: perceived social support and stressful life events. METHODS: From the entire 2013 cohort that underwent laparoscopic Roux-and-Y gastric bypass (LRYGB) in a general hospital in the Netherlands, a group of 56 non-responders and a matched group of 56 responders were selected, using an alterable weight loss (%AWL)-based percentile chart...
August 11, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28797697/changes-in-inflammatory-endometrial-cancer-risk-biomarkers-in-individuals-undergoing-surgical-weight-loss
#16
Faina Linkov, Sharon L Goughnour, Tianzhou Ma, Zhongying Xu, Robert P Edwards, Anna E Lokshin, Ramesh C Ramanathan, Giselle G Hamad, Carol McCloskey, Dana H Bovbjerg
OBJECTIVE: Obesity has been strongly linked to endometrial cancer (EC) risk. A number of potential EC risk biomarkers have been proposed, including heightened pro-inflammatory cytokines and adipokines. To evaluate if bariatric surgery can serve as a means for altering levels of such EC risk biomarkers, we investigated changes in these biomarkers after weight loss. METHODS: Blood samples were collected pre-operatively and 6months post-operatively in 107 female bariatric surgery patients aged 18-72years...
August 7, 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/28795980/cognitive-behavioral-therapy-and-predictors-of-weight-loss-in-bariatric-surgery-patients
#17
Linda Paul, Colin van der Heiden, Hans W Hoek
PURPOSE OF REVIEW: Bariatric surgery is the most effective treatment for morbid obesity. However, 20-30% of patients undergoing bariatric surgery experience premature weight stabilization or weight regain postoperatively. We report on the recent literature of predictors of weight loss and the efficacy of cognitive behavioral therapy (CBT) in bariatric patients. RECENT FINDINGS: Preoperative disordered eating behaviors do not appear to be significantly predictive of postoperative weight loss...
August 8, 2017: Current Opinion in Psychiatry
https://www.readbyqxmd.com/read/28794094/outcomes-of-50-patients-entering-an-adolescent-bariatric-surgery-programme
#18
Billy White, Jacqueline Doyle, Kirsten Matschull, Marco Adamo, Deborah Christie, Dasha Nicholls, Sanjay Kinra, Ian Chi Kei Wong, Russell M Viner
OBJECTIVE: Bariatric surgery is the most effective intervention for weight loss and obesity-related comorbidities currently available. Little is known about adolescents entering National Health Service (NHS) bariatric programmes. We aimed to characterise those entering a pathway and report their outcomes. DESIGN: Prospective service evaluation of patients assessed within a single NHS adolescent bariatric service. RESULTS: 50 patients assessed between 26 July 2007 and 27 January 2014; 6 (12%) were not eligible for surgery, 7 (14%) actively opted out, 8 (16%) were lost to follow-up and 29 (58%) underwent surgery (18 sleeve gastrectomy (SG) 11 Roux-en-y gastric bypass (RYGB) and 0 adjustable gastric band)...
August 9, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28770423/perceived-social-support-for-exercise-and-weight-loss-in-adolescents-undergoing-sleeve-gastrectomy
#19
Eleanor Race Mackey, Alexandra Olson, Stephanie Merwin, Jichuan Wang, Evan P Nadler
OBJECTIVES: Bariatric surgery is an effective treatment for youth with severe obesity. However, outcomes are variable and there remains sparse understanding of predictors of weight loss following surgery. The current study examines the role of adolescent-reported pre-operative social support around exercise, binge eating, and exercise to predict excess body mass index (EBMI) loss from 3 to 12 months post-surgery. METHOD: Participants were 101 adolescents ages 12-21 (M age = 16...
August 2, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28770185/intensive-nutrition-management-in-a-patient-with-short-bowel-syndrome-who-underwent-bariatric-surgery
#20
MeeRa Kweon, Dal Lae Ju, Misun Park, JiHyeong Choe, Yun-Suhk Suh, Eun-Mi Seol, Hyuk-Joon Lee
Many individuals with short bowel syndrome (SBS) require long-term parenteral nutrition (PN) to maintain adequate nutritional status. Herein, we report a successful intestinal adaptation of a patient with SBS through 13 times intensive nutritional support team (NST) managements. A thirty-five-year-old woman who could not eat due to intestinal discontinuity visited Seoul National University Hospital for reconstruction of the bowel. She received laparoscopic Roux-en-Y gastric bypass (RYGB) due to morbid obesity in Jan 2013 at a certain hospital and successfully reduced her weight from 110 kg to 68 kg...
July 2017: Clinical Nutrition Research
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