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https://www.readbyqxmd.com/read/28325023/an-affordable-cuff-less-blood-pressure-estimation-solution
#1
Monika Jain, Niranjan Kumar, Sujay Deb
This paper presents a cuff-less hypertension pre-screening device that non-invasively monitors the Blood Pressure (BP) and Heart Rate (HR) continuously. The proposed device simultaneously records two clinically significant and highly correlated biomedical signals, viz., Electrocardiogram (ECG) and Photoplethysmogram (PPG). The device provides a common data acquisition platform that can interface with PC/laptop, Smart phone/tablet and Raspberry-pi etc. The hardware stores and processes the recorded ECG and PPG in order to extract the real-time BP and HR using kernel regression approach...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28301143/ellagitannins-from-rubus-idaeus-l-exert-geno-and-cytotoxic-effects-against-the-human-colon-adenocarcinoma-cell-line-caco-2
#2
Adriana Nowak, Michał Sójka, Elżbieta Klewicka, Lidia Lipińska, Robert Klewicki, Krzysztof Kolodziejczyk
Ellagitannins possess several biological activities, including anti-cancer properties. The goal of the present study was to investigate the cyto- and genotoxic activity of a red raspberry ellagitannin preparation (REP) in the concentration range of 2.5-160 μg/mL, as well as that of the main individual raspberry ellagitannins: sanguiin H-6 (SH-6, 12.8-256 μM) and lambertianin C (LC, 9.3-378 μM), against the human colon adenocarcinoma cell line Caco-2. The ellagitannin concentrations used in the study correspond to those found in foodstuffs containing raspberry fruit...
March 16, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28277667/water-absorption-behavior-of-polystyrene-particles-prepared-by-emulsion-polymerization-with-nonionic-emulsifier-and-innovative-easy-synthesis-of-hollow-particles
#3
Masayoshi Okubo, Hiroshi Kobayashi, Chujuan Huang, Eri Miyanaga, Toyoko Suzuki
Submicrometer-sized raspberry-like polystyrene (PS) particles prepared by emulsion polymerization with polyoxyethylene nonylphenyl ether nonionic emulsifier (Emulgen 910, HLB 12.2) was incorporated 5.5 wt% (relative to PS) of Emulgen 910 and contained 8.5 vol% (relative to particle) of water in the inside. The water absorption decreased the glass transition temperature of PS particles dispersed in an aqueous medium. The wt% (relative to PS) of incorporated Emulgen 910 increased with increasing initial Emulgen 910 concentration in the emulsion polymerization but wt% (relative to total Emulgen 910 used) of the incorporated Emulgen 910 was constant at approximately 50% independently of the initial concentration...
March 9, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28274436/red-raspberry-rubus-idaeus-l-intake-decreases-oxidative-stress-in-obese-diabetic-db-db-mice
#4
Giuliana D Noratto, Boon P Chew, Liezl M Atienza
Red raspberry fruit intake was investigated on obese diabetic (db/db) mice for 8weeks. Animals fed isocaloric diets (5.3% freeze-dried raspberry, or control) were assessed for obesity-diabetes-disease risk biomarkers. Results showed that raspberry intake improved antioxidant status and lessened plasma interleukin (IL)-6 (0.3-fold of control, p<0.1); most likely through enhancing glutathione peroxidase (GPx) activity in liver (4.3-fold of control), and in blood (2.1-fold of control). Other disease-risk biomarkers were similar between groups (p>0...
July 15, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28273855/integration-of-traditional-and-metabolomics-biomarkers-identifies-prognostic-metabolites-for-predicting-responsiveness-to-nutritional-intervention-against-oxidative-stress-and-inflammation
#5
You Jin Kim, Iksoo Huh, Ji Yeon Kim, Saejong Park, Sung Ha Ryu, Kyu-Bong Kim, Suhkmann Kim, Taesung Park, Oran Kwon
Various statistical approaches can be applied to integrate traditional and omics biomarkers, allowing the discovery of prognostic markers to classify subjects into poor and good prognosis groups in terms of responses to nutritional interventions. Here, we performed a prototype study to identify metabolites that predict responses to an intervention against oxidative stress and inflammation, using a data set from a randomized controlled trial evaluating Korean black raspberry (KBR) in sedentary overweight/obese subjects...
March 4, 2017: Nutrients
https://www.readbyqxmd.com/read/28272923/inactivation-of-listeria-monocytogenes-on-frozen-red-raspberries-by-using-uv-c-light
#6
Yen-Te Liao, Roopesh M Syamaladevi, Hongchao Zhang, Karen Killinger, Shyam Sablani
In this study, the efficacy of UV-C treatment was determined on the reduction of foodborne pathogens on artificially contaminated frozen food surfaces. At first, the UV-C inactivation rates on 100 μl of the respective cocktails of Escherichia coli O157:H7, Salmonella , and Listeria monocytogenes covered underneath 0.5-cm-thick ice were examined. Simultaneously, the energy percentage of UV-C transmitted through the ice was determined. The experiments showed that more than 65% of the UV-C light energy passed through the ice and that UV-C susceptibility was in the descending order of E...
March 8, 2017: Journal of Food Protection
https://www.readbyqxmd.com/read/28268692/toward-a-low-cost-gait-analysis-system-for-clinical-and-free-living-assessment
#7
Cassim Ladha, Silvia Del Din, Kianoush Nazarpour, Aodhan Hickey, Rosie Morris, Michael Catt, Lynn Rochester, Alan Godfrey
Gait is an important clinical assessment tool since changes in gait may reflect changes in general health. Measurement of gait is a complex process which has been restricted to bespoke clinical facilities until recently. The use of inexpensive wearable technologies is an attractive alternative and offers the potential to assess gait in any environment. In this paper we present the development of a low cost analysis gait system built using entirely open source components. The system is used to capture spatio-temporal gait characteristics derived from an existing conceptual model, sensitive to ageing and neurodegenerative pathology (e...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28268361/robust-estimation-of-simulated-urinary-volume-from-camera-images-under-bathroom-illumination
#8
Chizuru Honda, Md Shoaib Bhuiyan, Haruki Kawanaka, Eiichi Watanabe, Koji Oguri
General uroflowmetry method involves the risk of nosocomial infections or time and effort of the recording. Medical institutions, therefore, need to measure voided volume simply and hygienically. Multiple cylindrical model that can estimate the fluid flow rate from the photographed image using camera has been proposed in an earlier study. This study implemented a flow rate estimation by using a general-purpose camera system (Raspberry Pi Camera Module) and the multiple cylindrical model. However, large amounts of noise in extracting liquid region are generated by the variation of the illumination when performing measurements in the bathroom...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28250585/mitigation-by-sodium-nitroprusside-of-the-effects-of-salinity-on-the-morpho-physiological-and-biochemical-characteristics-of-rubus-idaeus-under-in-vitro-conditions
#9
Ali Ghadakchiasl, Ali-Akbar Mozafari, Nasser Ghaderi
This study examined the changes brought about by sodium nitroprusside (SNP) in the effects of salinity on the morpho-physiological and biochemical characteristics of Rubus idaeus var. Danehdrosht. Raspberry shoot-tip explants were cultured on Murashige and Skoog medium supplemented with a growth regulator that combined benzyleadenine (1 mg/l), indol-3-butyric acetic acid (0.2 mg/l), SNP (0, 50 and 100 µM) and sodium chloride (0, 50 and 100 mM). The results showed that salinity stress significantly decreased morpho-physiological and biochemical characteristics such as RWC, MSI and total protein content in regenerated explants and significantly increased the total soluble sugar, proline contents, peroxidase and superoxide dismutase activity in compared to the control...
January 2017: Physiology and Molecular Biology of Plants: An International Journal of Functional Plant Biology
https://www.readbyqxmd.com/read/28246381/trienylfuranol-a-and-trienylfuranone-a-b-metabolites-isolated-from-an-endophytic-fungus-hypoxylon-submoniticulosum-in-the-raspberry-rubus-idaeus
#10
Kevin M N Burgess, Ashraf Ibrahim, Dan Sørensen, Mark W Sumarah
A strain of Hypoxylon submonticulosum was isolated as an endophyte from a surface-sterilized leaf of a cultivated raspberry (Rubus idaeus). The liquid culture extract displayed growth inhibition activity against Saccharomyces cerevisiae using a disc diffusion assay. The extract's major component was identified as a new natural product, trienylfuranol A (1S,2S,4R)-1-((1'E,3'E)-hexa-1',3',5'-trienyl)-tetrahydro-4-methylfuran-2-ol (1), by high-resolution LC-MS and 1D and 2D NMR spectroscopy. Two additional new metabolites, trienylfuranones A (2) and B (3), were isolated as minor components of the extract and their structure elucidation revealed that they were biosynthetically related to 1...
March 1, 2017: Journal of Antibiotics
https://www.readbyqxmd.com/read/28229020/an-open-source-device-for-operant-licking-in-rats
#11
Matthew Longley, Ethan L Willis, Cindy X Tay, Hao Chen
We created an easy-to-use device for operant licking experiments and another device that records environmental variables. Both devices use the Raspberry Pi computer to obtain data from multiple input devices (e.g., radio frequency identification tag readers, touch and motion sensors, environmental sensors) and activate output devices (e.g., LED lights, syringe pumps) as needed. Data gathered from these devices are stored locally on the computer but can be automatically transferred to a remote server via a wireless network...
2017: PeerJ
https://www.readbyqxmd.com/read/28227705/an-affordable-cuff-less-blood-pressure-estimation-solution
#12
Monika Jain, Niranjan Kumar, Sujay Deb, Monika Jain, Niranjan Kumar, Sujay Deb, Monika Jain, Sujay Deb, Niranjan Kumar
This paper presents a cuff-less hypertension pre-screening device that non-invasively monitors the Blood Pressure (BP) and Heart Rate (HR) continuously. The proposed device simultaneously records two clinically significant and highly correlated biomedical signals, viz., Electrocardiogram (ECG) and Photoplethysmogram (PPG). The device provides a common data acquisition platform that can interface with PC/laptop, Smart phone/tablet and Raspberry-pi etc. The hardware stores and processes the recorded ECG and PPG in order to extract the real-time BP and HR using kernel regression approach...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226879/toward-a-low-cost-gait-analysis-system-for-clinical-and-free-living-assessment
#13
Cassim Ladha, Silvia Del Din, Kianoush Nazarpour, Aodhan Hickey, Rosie Morris, Michael Catt, Lynn Rochester, Alan Godfrey, Cassim Ladha, Silvia Del Din, Kianoush Nazarpour, Aodhan Hickey, Rosie Morris, Michael Catt, Lynn Rochester, Alan Godfrey, Rosie Morris, Cassim Ladha, Lynn Rochester, Alan Godfrey, Aodhan Hickey, Silvia Del Din, Kianoush Nazarpour, Michael Catt
Gait is an important clinical assessment tool since changes in gait may reflect changes in general health. Measurement of gait is a complex process which has been restricted to bespoke clinical facilities until recently. The use of inexpensive wearable technologies is an attractive alternative and offers the potential to assess gait in any environment. In this paper we present the development of a low cost analysis gait system built using entirely open source components. The system is used to capture spatio-temporal gait characteristics derived from an existing conceptual model, sensitive to ageing and neurodegenerative pathology (e...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226524/robust-estimation-of-simulated-urinary-volume-from-camera-images-under-bathroom-illumination
#14
Chizuru Honda, Md Shoaib Bhuiyan, Haruki Kawanaka, Eiichi Watanabe, Koji Oguri, Chizuru Honda, Md Shoaib Bhuiyan, Haruki Kawanaka, Eiichi Watanabe, Koji Oguri, Eiichi Watanabe, Haruki Kawanaka, Chizuru Honda, Koji Oguri, Md Shoaib Bhuiyan
General uroflowmetry method involves the risk of nosocomial infections or time and effort of the recording. Medical institutions, therefore, need to measure voided volume simply and hygienically. Multiple cylindrical model that can estimate the fluid flow rate from the photographed image using camera has been proposed in an earlier study. This study implemented a flow rate estimation by using a general-purpose camera system (Raspberry Pi Camera Module) and the multiple cylindrical model. However, large amounts of noise in extracting liquid region are generated by the variation of the illumination when performing measurements in the bathroom...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28219012/tyrosinase-catalyzed-oxidation-of-the-leukoderma-inducing-agent-raspberry-ketone-produces-e-4-3-oxo-1-butenyl-1-2-benzoquinone-implications-for-melanocyte-toxicity
#15
Shosuke Ito, Maki Hinoshita, Erina Suzuki, Makoto Ojika, Kazumasa Wakamatsu
The exposure of human skin to 4-(4-hydroxyphenyl)-2-butanone (raspberry ketone, RK) is known to cause chemical/occupational leukoderma. RK has a structure closely related to 4-(4-hydroxyphenyl)-2-butanol (rhododendrol), a skin whitening agent that was found to cause leukoderma in the skin of consumers in 2013. Rhododendrol is a good substrate for tyrosinase and causes a tyrosinase-dependent cytotoxicity to melanocytes, cells that are responsible for skin pigmentation. Therefore, it is expected that RK exerts its cytotoxicity to melanocytes through the tyrosinase-catalyzed oxidation to cytotoxic o-quinones...
March 6, 2017: Chemical Research in Toxicology
https://www.readbyqxmd.com/read/28212306/metabolic-effects-of-berries-with-structurally-diverse-anthocyanins
#16
John Overall, Sierra A Bonney, Mickey Wilson, Arnold Beermann, Mary H Grace, Debora Esposito, Mary Ann Lila, Slavko Komarnytsky
Overconsumption of energy dense foods and sedentary lifestyle are considered as major causes of obesity-associated insulin resistance and abnormal glucose metabolism. Results from both cohort studies and randomized trials suggested that anthocyanins from berries may lower metabolic risks, however these reports are equivocal. The present study was designed to examine effects of six berries with structurally diverse anthocyanin profiles (normalized to 400 µg/g total anthocyanin content) on development of metabolic risk factors in the C57BL/6 mouse model of polygenic obesity...
February 15, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28192995/morphology-controlled-coating-of-colloidal-particles-with-silica-influence-of-particle-surface-functionalization
#17
Xu Dong, Pan Wu, Goetz P Hellmann, Changchun Wang, Christian G Schäfer
We present a general, convenient, and efficient synthetic concept for the coating of colloidal particles with a silica (SiO2) shell of well-defined and precisely controlled morphology and porosity. Monodisperse submicroscopic polystyrene (PS) particles were synthesized via two-stage emulsifier-free emulsion polymerization and subsequent swelling polymerization, enabling selective particle surface modification by the incorporation of ionic (methacrylic acid, MAA) or nonionic (hydroxyethyl methacrylate, HEMA or methacrylamide, MAAm) comonomers, which could be proven by zeta potential measurements as well as by determining the three-phase contact angle of the colloidal particles adsorbed at the air-water and n-decane-water interface...
February 21, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28161629/gene-expression-analysis-of-enzymes-of-the-carotenoid-biosynthesis-pathway-involved-in-%C3%AE-cryptoxanthin-accumulation-in-wild-raspberry-rubus-palmatus
#18
Kouichi Mizuno, Tetsuo Tokiwano, Yuko Yoshizawa
β-cryptoxanthin (β-Cry), a xanthophyll, is unlike other abundant carotenoids, such as α-carotene, β-carotene, lycopene, lutein, and zeaxanthin. It is not found in most fruits or vegetables but is found only in specific fruits, such as hot chili pepper, persimmon, and citrus fruits. Because recent reports suggest that β-Cry intake is beneficial to human health, the xanthophyll requires further investigation. Although β-Cry accumulates in the fruit of wild raspberry, Rubus palmatus, it is not present in cultivated raspberry...
February 2, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/28155269/self-assembled-raspberry-like-core-satellite-nanoparticles-for-anti-inflammatory-protein-delivery
#19
Tingting Wang, Yaqin Tang, Xiao He, Ju Yan, Chenhui Wang, Xuli Feng
Functional proteins are very promising for protein therapeutics; however, effective delivery of therapeutic proteins remains challenging. Herein, we developed novel core/satellite nanoparticles by tethering therapeutic proteins to the core/shell polymeric particle surface through cucurbit[8]uril (CB[8])-mediated host-guest interactions. The effectiveness of the core/satellite nanoparticles as protein carrier was demonstrated through the intra-articular delivery of interleukin-1 receptor antagonist (IL-1Ra)...
March 1, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28154430/distribution-and-longevity-of-pratylenchus-penetrans-in-the-red-raspberry-production-system
#20
Duncan R Kroese, Jerry E Weiland, Inga A Zasada
One of the major constraints on the production of red raspberries in the Pacific Northwest is the presence of the root-lesion nematode Pratylenchus penetrans. Current management of this nematode relies heavily on preplant soil fumigation; however, regulations have made the practice more difficult and expensive. Additional issues with soil fumigation include lack of efficacy at deeper soil depths and potential inability to penetrate raspberry root material that remains in the field during fumigation which may harbor P...
December 2016: Journal of Nematology
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