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Yaoyao Huang, Yang Hu, Lvcun Chen, Tao Yang, Hanfang Huang, Runping Shi, Peng Lu, Chenghua Zhong
Low-cost biosorbents (ginkgo leaf, osmanthus leaf, banyan leaf, magnolia leaf, holly leaf, walnut shell, and grapefruit peel) were evaluated in the simultaneous removal of La3+, Ce3+, Pr3+, Nd3+, Sm3+, Eu3+, Gd3+, Yb3+, Lu3+, UO22+, Th4+, Y3+, Co2+, Zn2+, Ni2+, and Sr2+ from aqueous solutions. In single metal systems, all adsorbents exhibited good to excellent adsorption capacities toward lanthanides and actinides. In a simulated multicomponent mixed solution study, higher selectivity and efficiency were observed for Th4+ over other metal cations, with ginkgo leaves providing the highest adsorptivity (81...
2018: PloS One
Zeynep Ciğeroğlu, Ömür Aras, Carlos A Pinto, Mahmut Bayramoglu, Ş İsmail Kırbaşlar, José M Lorenzo, Francisco J Barba, Jorge A Saraiva, Selin Şahin
BACKGROUND: The extraction of phenolic compounds from grapefruit leaves assisted by ultrasound-assisted extraction (UAE) was optimized using a response surface methodology (RSM) by means of D-optimal experimental design and artificial neural network (ANN). For this purpose, five numeric factors were selected: ethanol concentration (0-50 %), extraction time (15-60 min), extraction temperature (25-50 °C), solid/liquid ratio (50-100 g L-1 ) and calorimetric energy density of ultrasound (0...
March 6, 2018: Journal of the Science of Food and Agriculture
Abderrahim Nemmar, Suhail Al-Salam, Sumaya Beegam, Priya Yuvaraju, Naserddine Hamadi, Badreldin H Ali
Numerous studies have shown that acute particulate air pollution exposure is linked with pulmonary adverse effects, including alterations of pulmonary function, inflammation, and oxidative stress. Nootkatone, a constituent of grapefruit, has antioxidant and anti-inflammatory effects. However, the effect of nootkatone on lung toxicity has not been reported so far. In this study we evaluated the possible protective effects of nootkatone on diesel exhaust particles (DEP)-induced lung toxicity, and the possible mechanisms underlying these effects...
February 26, 2018: Nutrients
Tadataka Tsuji, Susumu Tanaka, Sanam Bakhshishayan, Mikihiko Kogo, Takashi Yamamoto
In both humans and animals, chemosensory stimuli, including odors and tastes, induce a variety of physiologic and mental responses related to energy homeostasis, such as glucose kinetics. The present study examined the importance of olfactory function in glucose kinetics following ingestion behavior in a simplified experimental scenario. We applied a conventional glucose tolerance test to rats with and without olfactory function and analyzed subsequent blood glucose (BG) curves in detail. The loss of olfactory input due to experimental damage to the olfactory mucosa induced a marked decrease in the area under the BG curve...
2018: International Journal of Medical Sciences
Shuo Duan, Hongge Jia, Zhiqian Pang, Doron Teper, Frank White, Jeffrey Jones, Changyong Zhou, Nian Wang
Xanthomonas citri ssp. citri (Xcc) is an important plant pathogenic bacterium that causes citrus canker disease worldwide. PthA, a transcriptional activator-like (TAL) effector, directs the expression of canker susceptibility gene CsLOB1. Here, we report our recent progress in functional characterization of CsLOB1. Subcellular localization analysis of CsLOB1 protein in citrus protoplast revealed that CsLOB1 is primarily localized in the nucleus. We showed that CsLOB1 expression driven by the dexamethasone (DEX) in the CsLOB1-GR transgenic plants is associated with pustule formation following treatment with DEX...
February 20, 2018: Molecular Plant Pathology
Kazuaki Iokawa, Masahiro Kohzuki, Toshimasa Sone, Satoru Ebihara
OBJECTIVE: To investigate the effect of olfactory stimulation with essential oils on cardiovascular reactivity during the "moving beans" rehabilitation task in stroke patients with anxiety. METHODS: Twenty-eight stroke patients participated in this study. Blood pressure and heart rate were measured before and after finger movement tasks (e.g., moving beans and the Purdue pegboard test). Olfactory stimulation with lavender oil, grapefruit oil, and distilled water were conducted during finger tasks...
February 2018: Complementary Therapies in Medicine
I La Mantia, G Ciprandi, A Varricchio, F Cupido, C Andaloro
Postnasal drip (PND)-related cough is a very common symptom in patients with upper respiratory tract infections (URTIs). At present, there is not a standard treatment for postnasal drip and postnasal drip-related cough. The aim of this pilot study was to evaluate the efficacy of a specific salso-bromo-iodine thermal water containing hyaluronic acid and grapefruit seed extract (SBI-H-GSE) comparing it with a normal saline solution in children with URTIs who refer PND-related symptoms. The study was randomized, single-blind, and controlled...
January 2018: Journal of Biological Regulators and Homeostatic Agents
Wenzheng Luo, Zhenyu Song, Hongwei Sun, Junxin Liang, Shanshan Zhao
The aim of the present study was to explore the effect of bergamottin, a natural furanocoumarin obtained from grapefruit juice, on the invasiveness of human glioma cells. The results revealed that treatment with bergamottin for 48 h significantly inhibited wound-healing migration and Matrigel invasion of human glioma cells, compared with untreated cells (P<0.05). Bergamottin treatment caused a significant decrease in the expression and secretion of matrix metalloproteinase (MMP)-9 in glioma cells compared with untreated cells (P<0...
March 2018: Oncology Letters
Jinlong Wu, Wenjun Deng, Dingbo Lin, Xiuxin Deng, Zhaocheng Ma
The inherent allergens of citrus fruits, such as Cit s 1, Cit s 2, Cit s 3 can cause allergic reactions. A better understanding of the genetic factors (cultivar to cultivar) affecting the allergenic potential of citrus fruits would be beneficial for further identification of hypoallergenic genotypes. In the present study, an immunoblotting quantification approach was adopted to assess the potential allergenicity of 21 citrus cultivars, including nine subgroups (tangerine, satsuma, orange, pummelo, grapefruit, lemon, kumquat, tangor and tangelo)...
February 8, 2018: Journal of Agricultural and Food Chemistry
Danielle Armas, Robert J Holt, Nils F Confer, Gregg C Checani, Mohammad Obaidi, Yuli Xie, Meg Brannagan
INTRODUCTION: Cystinosis is a rare, metabolic, autosomal recessive, genetic lysosomal storage disorder characterized by an accumulation of cystine in various organs and tissues. Cysteamine bitartrate (CB) is a cystine-depleting aminothiol agent approved in the United States and Europe in immediate-release and delayed-release (DR) formulations for the treatment of nephropathic cystinosis in children and adults. It is recommended that CBDR be administered with fruit juice (except grapefruit juice) for maximum absorption...
February 6, 2018: Advances in Therapy
Abderrahim Nemmar, Suhail Al-Salam, Sumaya Beegam, Priya Yuvaraju, Badreldin H Ali
Adverse cardiovascular effects of particulate air pollution persist even at lower concentrations than those of the current air quality limit. Therefore, identification of safe and effective measures against particles-induced cardiovascular toxicity is needed. Nootkatone is a sesquiterpenoid in grapefruit with diverse bioactivities including anti-inflammatory and antioxidant effects. However, its protective effect on the cardiovascular injury induced by diesel exhaust particles (DEP) has not been studied before...
January 5, 2018: American Journal of Physiology. Heart and Circulatory Physiology
Samira Sedehi, Hadi Tabani, Saeed Nojavan
In this work, polypropylene hollow fiber was replaced by agarose gel in conventional electro membrane extraction (EME) to develop a novel approach. The proposed EME method was then employed to extract two amino acids (tyrosine and phenylalanine) as model polar analytes, followed by HPLC-UV. The method showed acceptable results under optimized conditions. This green methodology outperformed conventional EME, and required neither organic solvents nor carriers. The effective parameters such as the pH values of the acceptor and the donor solutions, the thickness and pH of the gel, the extraction voltage, the stirring rate, and the extraction time were optimized...
March 1, 2018: Talanta
Kayako Ogi, Takako Otsuka, Hidenobu Sumitani
Exposure to light may adversely affect the quality of foods. This investigation of how light exposure affects citrus (orange and mandarin blend) juice in polyethylene terephthalate (PET) bottles demonstrated that the isomeric form of a compound in the juice changed during storage. This compound was identified as feruloylputrescine (FP; CAS: 501-13-3; C14H20N2O3) using LC/MS (Q-TOF). LC/MS and NMR measurements showed that the content of the original form, trans-FP, decreased as it isomerized to cis-FP during storage...
January 5, 2018: Bioscience, Biotechnology, and Biochemistry
Alberto M Gochez, Jose C Huguet-Tapia, Gerald V Minsavage, Deepak Shantaraj, Neha Jalan, Annett Strauß, Thomas Lahaye, Nian Wang, Blanca I Canteros, Jeffrey B Jones, Neha Potnis
BACKGROUND: Xanthomonas citri, a causal agent of citrus canker, has been a well-studied model system due to recent availability of whole genome sequences of multiple strains from different geographical regions. Major limitations in our understanding of the evolution of pathogenicity factors in X. citri strains sequenced by short-read sequencing methods have been tracking plasmid reshuffling among strains due to inability to accurately assign reads to plasmids, and analyzing repeat regions among strains...
January 4, 2018: BMC Genomics
Michael Grimm, Mirko Koziolek, Marwa Saleh, Felix Schneider, Grzegorz Garbacz, Jens Peter Kuhn, Werner Weitschies
Grapefruit juice (GFJ) is known to affect the bioavailability of drugs in different ways. Despite the influence on gastrointestinal enzymes and transporters, the influence on gastrointestinal fluid kinetics is regarded to be relevant for the absorption of several drugs. Thus, it was the aim of this pilot study to investigate the gastric and intestinal volumes after intake of GFJ compared to isocaloric fructose and glucose solutions and water. The gastric and small intestinal volume kinetics after intake of 240 mL of GFJ, 10...
January 3, 2018: Molecular Pharmaceutics
José Melesio Cristóbal-Luna, Isela Álvarez-González, Eduardo Madrigal-Bujaidar, Germán Chamorro-Cevallos
Grapefruit (Citrus paradisi Mcfad) is a perenifolium tree 5-6 m high with a fruit of about 15 cm in diameter, protected by the peel we can find about 11-14 segments (carpels), each of which is surrounded by a membrane and each containing the juice sacs, as well as the seeds. The fruit is made up of numerous compounds, and is known to have nutritive value because of the presence of various vitamins and minerals, among other chemicals. The fruit is also used in the field of gastronomy. Information has been accumulated regarding the participation of the fruit structures in a variety of biomedical, antigenotoxic and chemopreventive effects, surely related with the presence of the numerous chemicals that have been determined to constitute the fruit...
December 25, 2017: Food and Chemical Toxicology
Nohemi Soto-Reyes, Aurelio Lopez-Malo, Roberto Rojas-Laguna, Julián Andrés Gómez-Salazar, María Elena Sosa-Morales
BACKGROUND: Hot water treatment (HWT) against Anastrepha ludens were developed achieving 48°C in the core of grapefruits and holding it for 6 min. After heating, the grapefruits were hydro-cooled and stored at 23°C and analyzed for 16 days. The effect of microwave-assisted hot water treatment (MW-HWT) on grapefruit quality was analyzed and compared with the quality of fruits treated with HWT and control fruits (without treatment). The physico-chemical properties and chemical composition of essential oil were analyzed...
December 18, 2017: Journal of the Science of Food and Agriculture
Rie Iijima, Tomoki Watanabe, Kan'ichiro Ishiuchi, Takashi Matsumoto, Junko Watanabe, Toshiaki Makino
ETHNOPHARMACOLOGICAL RELEVANCE: The use of herbal medicines has become popular worldwide, and the information on drug interactions between herbal medicines and chemical drugs is needed. AIM OF THE STUDY: We screened the inhibitory effects of crude drugs used in Kampo medicines used in Japan on organic anion-transporting polypeptide (OATP) 2B1 to predict potential interactions between Kampo medicines and chemical drugs used together. MATERIALS AND METHODS: We chose 98 kinds of crude drugs frequently used as ingredients of Kampo formulations in Japan and prepared their boiling water extracts...
December 14, 2017: Journal of Ethnopharmacology
Jin Sung Won, Seung Jo Lee, Hyeon Hwa Park, Kyung Bin Song, Sea C Min
Grapefruit seed extract (GSE)-containing chitosan-based coating was developed and applied to cherry tomatoes to protect them from Salmonella invasion and improve their storability. The coating colloids were produced by mixing a chitosan colloid (1% [w/w] chitosan) with GSE at various concentrations (0.5%, 0.7%, 1.0%, and 1.2% [w/w]) using high-shear mixing (10000 rpm, 2 min). Coatings with chitosan colloids containing GSE at 0.0%, 0.5%, 0.7%, and 1.0% (w/w) inactivated Salmonella on cherry tomatoes by 1.0 ± 0...
January 2018: Journal of Food Science
A Birke, M Aluja
The preference-performance hypothesis (PPH) has widely been used to explain host exploitation patterns by phytophagous insects. However, this hypothesis often fails in the case of polyphagous species when compared with specialists. One explanation, validated by the information-processing hypothesis (IPH), considers that polyphagous insects are unable to process a large array of cues, which hinders females from distinguishing between high- and low- quality hosts. Here we analyzed Anastrepha ludens female host preference and offspring performance, and tested if neuronal limitations could possibly play a role in the incapacity of the polyphagous A...
December 4, 2017: Bulletin of Entomological Research
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