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hemp seed oil

Matteo Chinello, Salvatore Scommegna, Alison Shardlow, Francesca Mazzoli, Nadia De Giovanni, Nadia Fucci, Paola Borgiani, Cinzia Ciccacci, Anna Locasciulli, Mauro Calvani
We report a case of mild cannabinoid poisoning in a preschool child, after 3-week ingestion of hemp seed oil prescribed by his pediatrician to strengthen his immune system. The patient presented neurological symptoms that disappeared after intravenous hydration. A possible mild withdrawal syndrome was reported after discharge. The main metabolite of Δ-tetrahydrocannabinol was detected in urine, and very low concentration of Δ-tetrahydrocannabinol was detected in the ingested product. This is, as far as we know, the first report of cannabinoid poisoning after medical prescription of hemp seed oil in a preschool child...
June 14, 2016: Pediatric Emergency Care
Incoronata Galasso, Roberto Russo, Sergio Mapelli, Elena Ponzoni, Ida M Brambilla, Giovanna Battelli, Remo Reggiani
The seed of Cannabis sativa L. is an expanding source of proteins and oil for both humans and animals. In this study, the proximate composition of a collection of hemp cultivars and accessions of different geographical origins grown under the same conditions for 1 year was analyzed in order to identify potential accessions to improve hemp cultivars. Fatty acids, tocopherols, and antinutritional components, as well as concentrations of crude protein and oil were quantified. The seed oil concentrations varied between 285 and 360 g kg(-1) dry seed (DS), while crude protein ranged between 316 and 356 g kg(-1) dry matter (DM)...
2016: Frontiers in Plant Science
Antonella Smeriglio, Enza M Galati, Maria T Monforte, Francesco Lanuzza, Valeria D'Angelo, Clara Circosta
The aim of this study was to characterize the polyphenolic compounds and antioxidant activity of cold-pressed seed oil from Finola cultivar of industrial hemp (Cannabis sativa L.). Several methodologies have been employed to evaluate the in vitro antioxidant activity of Finola hempseed oil (FHSO) and both lipophilic (LF) and hydrophilic fractions (HF). The qualitative and quantitative composition of the phenolic fraction of FHSO was performed by HPLC analyses. From the results is evident that FHSO has high antioxidative activity, as measured by DPPH radical (146...
August 2016: Phytotherapy Research: PTR
Soheila Rezapour-Firouzi, Seyed Rafie Arefhosseini, Mehrangiz Ebrahimi-Mamaghani, Behzad Baradaran, Elyar Sadeghihokmabad, Somaiyeh Mostafaei, Mohammadali Torbati, Mahtaj Chehreh
BACKGROUND: The effect of nutrition and dietary supplements as environmental factors has been suggested as possible factors affecting both disease risk and progression in on the course of multiple sclerosis with complex genetic-risk profiles. This study was aimed to assess regulation of surface-membrane enzymes such as Delta-6-desaturase (FADS2), secretory Phospholipase A2(sPLA2) by hemp seed and evening primrose oils as well as Hot-natured dietary intervention in relapsing remitting multiple sclerosis (RRMS) patients...
October 2015: Complementary Therapies in Medicine
Jana Orsavova, Ladislava Misurcova, Jarmila Vavra Ambrozova, Robert Vicha, Jiri Mlcek
Characterizations of fatty acids composition in % of total methylester of fatty acids (FAMEs) of fourteen vegetable oils--safflower, grape, silybum marianum, hemp, sunflower, wheat germ, pumpkin seed, sesame, rice bran, almond, rapeseed, peanut, olive, and coconut oil--were obtained by using gas chromatography (GC). Saturated (SFA), monounsaturated (MUFA) and polyunsaturated fatty acids (PUFA), palmitic acid (C16:0; 4.6%-20.0%), oleic acid (C18:1; 6.2%-71.1%) and linoleic acid (C18:2; 1.6%-79%), respectively, were found predominant...
2015: International Journal of Molecular Sciences
Sue-Siang Teh, Gertrud E Morlock
Cold-pressed hemp, flax and canola seed oils are healthy oils for human consumption as these are rich in polyunsaturated fatty acids and bioactive phytochemicals. However, bioactive information on the food intake side is mainly focused on target analysis. For more comprehensive information with regard to effects, single bioactive compounds present in the seed oil extracts were detected by effect-directed assays, like bioassays or an enzymatic assay, directly linked with chromatography and further characterized by mass spectrometry...
November 15, 2015: Food Chemistry
C Da Porto, A Natolino, D Decorti
Ultrasound pre-treatment of intact hemp seeds without any solvent assistance was carried out for 10, 20 and 40 min prior to SCCO2 extraction at 40 °C, 300 bar and 45 kg CO2/kg feed. Sonication time effect on SC-CO2 extraction was investigated by the extraction kinetics. The maximum extraction yield was estimated to be 24.03 (% w/w) after 10 min of ultrasonic pre-treatment. The fatty acid compositions of the oils extracted by SC-CO2 without and with ultrasound pre-treatments was analyzed using gas chromatography...
March 2015: Journal of Food Science and Technology
Soheila Rezapour-Firouzi, Seyed Rafie Arefhosseini, Mehrangiz Ebrahimi-Mamaghani, Behzad Baradaran, Elyar Sadeghihokmabad, Mohammadali Torbati, Somaiyeh Mostafaei, Mahtaj Chehreh, Fatemeh Zamani
BACKGROUND: It is unknown whether diets with a high dietary total antioxidant capacity (TAC) can modify oxidative stress, low-grade inflammation, or liver dysfunction, all of which are risk factors for multiple sclerosis disease. This study assesses alanine amino-transferase (ALT), aspartate-aminotransferase (AST) and gamma-glutamyl transferase (GGT) activities in MS patients treated with co-supplemented hemp seed and evening primrose oils as well as Hot-nature diet and the therapeutic potential this intervention...
December 2014: Complementary Therapies in Medicine
Milica Pojić, Aleksandra Mišan, Marijana Sakač, Tamara Dapčević Hadnađev, Bojana Šarić, Ivan Milovanović, Miroslav Hadnađev
Valorization of hemp seed meal, a byproduct of hemp oil processing, was performed by measuring the distribution of nutritional and antinutritional compounds in different hemp seed meal fractions. According to chemical composition, two cotyledon-containing fractions (>180 and <180 μm) were significantly richer in protein (p < 0.05) (41.2% ± 0.04% and 44.4% ± 0.02%, respectively), lipid (15.1% ± 0.02% and 18.6% ± 0.04%, respectively), and sugar content (4.96% ± 0.11% and 3.46% ± 0.08%, respectively) in comparison to the hull-containing fractions (>350 and >250 μm), which were significantly richer in crude fiber content (29...
December 24, 2014: Journal of Agricultural and Food Chemistry
Sunday A Malomo, Rong He, Rotimi E Aluko
The effects of pH and protein concentration on some structural and functional properties of hemp seed protein isolate (HPI, 84.15% protein content) and defatted hemp seed protein meal (HPM, 44.32% protein content) were determined. The HPI had minimum protein solubility (PS) at pH 4.0, which increased as pH was decreased or increased. In contrast, the HPM had minimum PS at pH 3.0, which increased at higher pH values. Gel electrophoresis showed that some of the high molecular weight proteins (>45 kDa) present in HPM were not well extracted by the alkali and were absent or present in low ratio in the HPI polypeptide profile...
August 2014: Journal of Food Science
Sang-Oh Park, Jong Hwangbo, In-Suh Yuh, Byung-Sung Park
This study was carried out to find out the effect of supplying gamma linolenic acid (GLA) on laying performance and egg quality. A hundred twenty of 30 weeks old hyline brown laying hens with 98% of egg production were completely randomized to 4 different treatment groups by 30 hens (the control group fed with the diet containing beef tallow, 3 treatment groups fed with the diet containing corn oil, the diet containing hemp seed oil and the diet containing evening primrose oil, respectively), and their laying performance and egg production were investigated for 5 weeks...
July 2014: Journal of Environmental Biology
G Lesma, R Consonni, V Gambaro, C Remuzzi, G Roda, A Silvani, V Vece, G L Visconti
Within a project aimed to reintroduce non-drug hemp cultivars in the Italian Po valley, for fibre but also high added-value nutraceutical production, investigation on locally grown plants has been performed, in order to assess their oil and metabolic content. This study provides useful information regarding three different hemp cultivars, from two sites, in view of their potential industrial application. The oil was characterised by a high unsaturated/saturated fatty acid ratio and by an almost perfect balance of ω-3 and ω-6 fatty acids, as requested for healthy foods...
2014: Natural Product Research
Alok Patel, Mohammad Pravez, Farha Deeba, Vikas Pruthi, Rajesh P Singh, Parul A Pruthi
Hemp seeds aqueous extract (HSAE) was used as cheap renewable feedstocks to grow novel oleaginous yeast Rhodosporidium kratochvilovae HIMPA1 isolated from Himalayan permafrost soil. The yeast showed boosted triglyceride (TAG) accumulation in the lipid droplets (LDs) which were transesterified to biodiesel. The sonicated HSAE prepared lacked toxic inhibitors and showed enhanced total lipid content and lipid yield 55.56%, 8.39±0.57g/l in comparison to 41.92%, 6.2±0.8g/l from industrially used glucose synthetic medium, respectively...
August 2014: Bioresource Technology
Olga Radočaj, Etelka Dimić, Rong Tsao
UNLABELLED: A mixture, simplex centroid, 2 components experimental design was used to evaluate the addition of hemp seed oil press-cake and decaffeinated green tea leaves, as functional ingredients to assess nutritional characteristics and antioxidant properties of gluten-free crackers. All samples with added hemp flour had much better nutritional qualities than the brown rice flour crackers in terms of higher protein, crude fibers, minerals, and essential fatty acids content. Likewise, all samples with added decaffeinated green tea leaves had much better antioxidant properties than crackers with no added green tea leaves...
March 2014: Journal of Food Science
Monika Bielecka, Filip Kaminski, Ian Adams, Helen Poulson, Raymond Sloan, Yi Li, Tony R Larson, Thilo Winzer, Ian A Graham
We used expressed sequence tag library and whole genome sequence mining to identify a suite of putative desaturase genes representing the four main activities required for production of polyunsaturated fatty acids in hemp seed oil. Phylogenetic-based classification and developing seed transcriptome analysis informed selection for further analysis of one of seven Δ12 desaturases and one of three Δ15 desaturases that we designate CSFAD2A and CSFAD3A, respectively. Heterologous expression of corresponding cDNAs in Saccharomyces cerevisiae showed CSFAD2A to have Δx+3 activity, while CSFAD3A activity was exclusively at the Δ15 position...
June 2014: Plant Biotechnology Journal
Paweł Górnaś, Aleksander Siger, Iveta Pugajeva, Dalija Segliņa
Thirteen cold-pressed oils (Japanese quince seed, black caraway, flaxseed, rapeseed, hemp, peanut, sunflower, pumpkin, hazelnut, poppy, walnut, almond and sesame oil) manufactured by the same company over a 2-year period (2011-12) were assessed for lipophilic compounds. The presence of sesamin and sesamolin, two characteristic lignans of sesame oil, were detected in all tested plant oils. Both lignans were identified by NP-HPLC/FLD/DAD and confirmed by a RP-UPLC-ESI/MS(n) method. The lowest amount of sesamin and sesamolin was found for Japanese quince seed oil (0...
April 2014: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
S Montserrat-de la Paz, F Marín-Aguilar, M D García-Giménez, M A Fernández-Arche
Non-drug varieties of Cannabis sativa L., collectively namely as "hemp", have been an interesting source of food, fiber, and medicine for thousands of years. The ever-increasing demand for vegetables oils has made it essential to characterize additional vegetable oil through innovative uses of its components. The lipid profile showed that linoleic (55%), α-linolenic (16%), and oleic (11%) were the most abundant fatty acids. A yield (1.84-1.92%) of unsaponifiable matter was obtained, and the most interesting compounds were β-sitosterol (1905...
February 5, 2014: Journal of Agricultural and Food Chemistry
Soheila Rezapour-Firouzi, Seyed Rafie Arefhosseini, Mehrangiz Ebrahimi-Mamaghani, Mehdi Farhoudi, Behzad Baradaran, Torbati Mohammad Ali, Fatemeh Zamani
The risk of developing multiple sclerosis (MS) is associated with increased dietary intake of saturated fatty acids. For many years it has been suspected that this disease might be associated with an imbalance between unsaturated and saturated fatty acids. We determined erythrocyte membrane fatty acids levels in Hot nature dietary intervention with co-supplemented hemp seed and evening primrose oils in multiple sclerosis patients. To determine the erythrocyte membrane fatty acids levels and correlate it with expanded disability status scale (EDSS) at baseline after 6 months intervention in MS patients by gas chromatography, in this double blind, randomized trial, 100 RRMS patients with EDSS<6 were allocated into three groups: "Group A" that received co-supplemented hemp seed and evening primrose oils with advised Hot nature diet...
2013: African Journal of Traditional, Complementary, and Alternative Medicines: AJTCAM
Soheila Rezapour-Firouzi, Seyed Rafie Arefhosseini, Farhoudi Mehdi, Ebrahimi-Mamaghani Mehrangiz, Behzad Baradaran, Elyar Sadeghihokmabad, Somaiyeh Mostafaei, Seyed Mohammad Bagher Fazljou, Mohammad-ali Torbati, Sarvin Sanaie, Fatemeh Zamani
BACKGROUND: Multiple sclerosis (MS) is the most chronic and inflammatory disorder. Because of limited efficacy and adverse side effects, identifying novel therapeutic and protective agents is important. This study was aimed to assess the potential therapeutic effects of hemp seed and evening primrose oils as well as Hot-nature dietary intervention on RRMS patients. METHODS AND MATERIALS: In this double blind, randomized trial, 100 MS patients with EDSS<6 were allocated into 3 groups: "Group A" who received co-supplemented hemp seed and evening primrose oils with advised Hot-nature diet, "Group B" who received olive oil, "Group C" who received the co-supplemented oils...
October 2013: Complementary Therapies in Medicine
Soheila Rezapour-Firouzi, Seyed Rafie Arefhosseini, Mehdi Farhoudi, Mehrangiz Ebrahimi-Mamaghani, Mohammad-Reza Rashidi, Mohammad-Ali Torbati, Behzad Baradaran
INTRODUCTION: Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system (CNS). Because of limited efficacy and adverse side effects, identifying novel therapeutic and protective agents is important. The aim of this study is to examine the correlations between expanded disability status scale (EDSS) and cytokines after intervention with co-supplemented hemp seed and evening primrose oils and hot-natured diet in patients with relapsing-remitting multiple sclerosis (RRMS)...
2013: BioImpacts: BI
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