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https://www.readbyqxmd.com/read/29906260/the-comparative-genomics-of-bifidobacterium-callitrichos-reflects-dietary-carbohydrate-utilization-within-the-common-marmoset-gut
#1
Korin Albert, Asha Rani, David A Sela
Bifidobacterium is a diverse genus of anaerobic, saccharolytic bacteria that colonize many animals, notably humans and other mammals. The presence of these bacteria in the gastrointestinal tract represents a potential coevolution between the gut microbiome and its mammalian host mediated by diet. To study the relationship between bifidobacterial gut symbionts and host nutrition, we analyzed the genome of two bifidobacteria strains isolated from the feces of a common marmoset (Callithrix jacchus), a primate species studied for its ability to subsist on host-indigestible carbohydrates...
June 15, 2018: Microbial Genomics
https://www.readbyqxmd.com/read/29896319/specific-properties-of-probiotic-strains-relevance-and-benefits-for-the-host
#2
Rostyslav V Bubnov, Lidiia P Babenko, Liudmyla M Lazarenko, Victoria V Mokrozub, Mykola Ya Spivak
Background: Probiotics have tremendous potential to develop healthy diets, treatment, and prevention. Investigation of in vitro cultural properties of health-promoting microorganisms like lactic acid bacteria (LAB) and bifidobacteria is crucial to select probiotic strains for treatments based on gut microbiota modulation to justify individualized and personalized approach for nutrition and prevention of variety of diseases. The aim was to study the biological properties of LAB and bifidobacteria probiotic strains, namely adhesive properties; resistance to antibiotics; and biological fluids (gastric juice, bile, pancreatic enzymes), and to overview the literature in the field...
June 2018: EPMA Journal
https://www.readbyqxmd.com/read/29892745/bifidobacteria-attenuate-the-development-of-metabolic-disorders-with-inter-and-intra-species-differences
#3
Guangsu Zhu, Fangli Ma, Gang Wang, Yuanyuan Wang, Jianxin Zhao, Hao Zhang, Wei Chen
Host gut microbiota dysbiosis occurs for multiple reasons and is often accompanied by chronic inflammation induced by a high-fat-high-sucrose (HFHS) diet and related metabolic disorders. Intervention with probiotics is a novel strategy for amelioration of metabolic syndrome, which is believed to regulate the gut microbiota composition to some extent. We investigated the relationship amongst bifidobacteria treatment, HFHS diet-induced metabolic disorders and the gut microbiota composition. Seven strains of bifidobacteria from four species were individually administered to rats fed a HFHS diet for 12 weeks...
June 12, 2018: Food & Function
https://www.readbyqxmd.com/read/29888657/oral-administration-of-bifidobacterium-bifidum-tmc3115-to-neonatal-mice-may-alleviate-ige-mediated-allergic-risk-in-adulthood
#4
R Y Cheng, J R Yao, Q Wan, J W Guo, F F Pu, L Shi, W Hu, Y H Yang, L Li, M Li, F He
This study aimed to demonstrate whether exposure to bifidobacteria during early life influences immunity and alleviates the risk of immunoglobulin E (IgE)-mediated allergies in adulthood. BALB/c neonatal mice (n=54) were administered with a lyophilised cell preparation of Bifidobacterium bifidum TMC3115 (TMC3115) for 3 weeks. Following the intervention, the mice were immunised with intraperitoneal ovalbumin (OVA). The morphology and function of the intestinal epithelium were determined using histopathological examinations...
June 11, 2018: Beneficial Microbes
https://www.readbyqxmd.com/read/29888226/three-month-feeding-integration-with-bifidobacterium-strains-prevents-gastrointestinal-symptoms-in-healthy-newborns
#5
Irene Aloisio, Flavia Prodam, Enza Giglione, Nicole Bozzi Cionci, Arianna Solito, Simonetta Bellone, Loredana Baffoni, Luca Mogna, Marco Pane, Gianni Bona, Diana Di Gioia
Infantile functional gastrointestinal disorders are common in the first months of life. Their pathogenesis remains unknown although evidences suggest multiple independent causes, including gut microbiota modifications. Feeding type, influencing the composition of intestinal microbiota, could play a significant role in the pathogenesis. Previous studies supported probiotic supplementation success against colics, however mainly Lactobacillus spp. were tested. The aim of this study was to evaluate the effectiveness against functional gastrointestinal disorders of a Bifidobacterium breve based probiotic formulation including in the study both breast-fed and bottle-fed subjects...
2018: Frontiers in Nutrition
https://www.readbyqxmd.com/read/29884754/reconstruction-of-the-bifidobacterial-pan-secretome-reveals-the-network-of-extracellular-interactions-between-bifidobacteria-and-the-infant-gut
#6
Gabriele Andrea Lugli, Walter Mancino, Christian Milani, Sabrina Duranti, Francesca Turroni, Douwe van Sinderen, Marco Ventura
The repertoire of secreted proteins decoded by a microorganism represents proteins released from or associated with the cell's surface. In gut commensals, such as bifidobacteria, these proteins are perceived to be functionally relevant as they regulate the interaction with the gut environment. In the current study, we have screened the predicted proteome of over 300 bifidobacterial strains amongst the currently recognized bifidobacterial species to generate a comprehensive database encompassing bifidobacterial extracellular proteins...
June 8, 2018: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/29847302/analysis-of-polyamine-biosynthetic-and-transport-ability-of-human-indigenous-bifidobacterium
#7
Yuta Sugiyama, Misaki Nara, Mikiyasu Sakanaka, Aya Kitakata, Shujiro Okuda, Shin Kurihara
Bifidobacteria are members of the human intestinal microbiota, being numerically dominant in the colon of infants, and also being prevalent in the large intestine of adults. In this study, we measured the concentrations of major polyamines (putrescine, spermidine, and spermine) in cells and culture supernatant of 13 species of human indigenous Bifidobacterium at growing and stationary phase. Except for Bifidobacterium bifidum and Bifidobacterium gallicum, 11 species contained spermidine and/or spermine when grown in Gifu-anaerobic medium (GAM)...
May 30, 2018: Bioscience, Biotechnology, and Biochemistry
https://www.readbyqxmd.com/read/29802187/-bifidobacterium-pseudolongum-has-characteristics-of-a-keystone-species-in-bifidobacterial-blooms-in-the-ceca-of-rats-fed-hi-maize-starch
#8
Manuela Centanni, Blair Lawley, Christine A Butts, Nicole Roy, Julian Lee, William J Kelly, Gerald W Tannock
Starches resistant to mammalian digestion are present in foods and pass to the large bowel where they may be degraded and fermented by the microbiota. Increases in relative abundances of bifidobacteria (blooms) have been reported in rats whose diet was supplemented with Hi-Maize resistant starch. We determined that the bifidobacterial species present in the rat cecum under these circumstances mostly belonged to Bifidobacterium animalis However, cultures of B. animalis isolated from the rats failed to degrade Hi-Maize starch to any extent...
May 25, 2018: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/29794423/pathophysiology-of-dental-caries
#9
Georg Conrads, Imad About
Carious lesion dynamics are dependent predominantly on the availability of fermentable sugars, other environmental conditions, bacteria, and host factors. Our current understanding of the microorganisms involved in the initiation and progression of caries is still rather incomplete. The most relevant acidogenic-aciduric bacterial species known to date are Streptococcus mutans, bifidobacteria, and lactobacilli. Whereas mutans streptococci are initiators, bifidobacteria and lactobacilli are more enhancers for progression...
May 24, 2018: Monographs in Oral Science
https://www.readbyqxmd.com/read/29777696/sterilized-bifidobacteria-suppressed-fat-accumulation-and-blood-glucose-level
#10
Keita Kikuchi, Mahmoud Ben Othman, Kazuichi Sakamoto
Probiotics such as Lactobacillus and Bifidobacterium improve the balance of intestinal microflora and have various physiological functions beneficial to human health. It is not always known whether the ingested microbial cells are viable- or killed. However, even sterilized bacterial cells are functional. Bacterial cell functions are strain-specific and their modes of action are still poorly understood. The aim of this study was to elucidate the roles of sterilized bifidobacteria in obesity and lipid metabolism...
May 16, 2018: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/29748815/improved-hemodynamic-and-liver-function-in-portal-hypertensive-cirrhotic-rats-after-administration-of-b-pseudocatenulatum-cect-7765
#11
Isabel Gómez-Hurtado, Pedro Zapater, Kevin Portune, Oriol Juanola, Anabel Fernández-Iglesias, José M González-Navajas, Jordi Gracia-Sancho, Yolanda Sanz, Rubén Francés
PURPOSE: Evaluating whether changes in gut microbiota induced by a bifidobacterial strain may have an effect on the hepatic vascular function in portal hypertensive cirrhotic rats. METHODS: Bile duct ligation (BDL) was performed in rats. A subgroup of animals received B. pseudocatenulatum CECT7765 (109  cfu/daily ig.) for 1 week prior to laparotomy. Hemodynamic, biochemical and inflammatory markers were evaluated. Ileal microbiota composition was identified. Statistical analysis was performed...
May 10, 2018: European Journal of Nutrition
https://www.readbyqxmd.com/read/29745350/resistant-starch-reduces-large-intestinal-ph-and-promotes-fecal-lactobacilli-and-bifidobacteria-in-pigs
#12
B U Metzler-Zebeli, N Canibe, L Montagne, J Freire, P Bosi, J A M Prates, S Tanghe, P Trevisi
Dietary resistant starch (RS) may have prebiotic properties but its effects on fermentation and the microbial population are inconsistent. This meta-analysis aimed to quantify the relationship between RS type 2 (RS2) and intestinal short-chain fatty acids (SCFA) and pH as well as certain key bacterial taxa for intestinal health in pigs. From the 24 included articles with sufficient information about the animal, and dietary and physiological measurements published between 2000 and 2017, individual sub-data sets for fermentation metabolites, pH, bacterial abundances and apparent total tract digestibility were built and used to parameterize prediction models on the effect of RS2, accounting for inter- and intra-study variability...
May 10, 2018: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/29740413/comparative-genomics-reveals-the-regulatory-complexity-of-bifidobacterial-arabinose-and-arabino-oligosaccharide-utilization
#13
Aleksandr A Arzamasov, Douwe van Sinderen, Dmitry A Rodionov
Members of the genus Bifidobacterium are common inhabitants of the human gastrointestinal tract. Previously it was shown that arabino-oligosaccharides (AOS) might act as prebiotics and stimulate the bifidobacterial growth in the gut. However, despite the rapid accumulation of genomic data, the precise mechanisms by which these sugars are utilized and associated transcription control still remain unclear. In the current study, we used a comparative genomic approach to reconstruct arabinose and AOS utilization pathways in over 40 bacterial species belonging to the Bifidobacteriaceae family...
2018: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29734011/the-ability-of-human-intestinal-anaerobes-to-metabolize-different-oligosaccharides-novel-means-for-microbiota-modulation
#14
Riichi Ose, Katsuaki Hirano, Shintaro Maeno, Junichi Nakagawa, Seppo Salminen, Takumi Tochio, Akihito Endo
Prebiotic oligosaccharides are known to have significant impacts on gut microbiota and are thus widely used to program healthy microbiota composition and activity from infants to the elderly. Bifidobacteria and lactobacilli are among the major target microorganisms of oligosaccharides, but the metabolic properties of oligosaccharides in other predominant gut microbes have not been well characterized. In the present study, we demonstrated the metabolic properties of six oligosaccharides in 31 key gut anaerobes...
May 4, 2018: Anaerobe
https://www.readbyqxmd.com/read/29705500/lactobacillus-paracasei-hii01-xylooligosaccharides-and-synbiotics-reduce-gut-disturbance-in-obese-rats
#15
Parameth Thiennimitr, Sakawdaurn Yasom, Wannipa Tunapong, Titikorn Chunchai, Keerati Wanchai, Anchalee Pongchaidecha, Anusorn Lungkaphin, Sasithorn Sirilun, Chaiyavat Chaiyasut, Nipon Chattipakorn, Siriporn C Chattipakorn
OBJECTIVES: The beneficial effects of pro-, pre-, and synbiotics on obesity with insulin resistance have been reported previously. However, the strain-specific effect of probiotics and the combination with various types of prebiotic fiber yield controversial outcomes and limit clinical applications. Our previous study demonstrated that the probiotic Lactobacillus paracasei (L. paracasei) HII01, prebiotic xylooligosaccharide (XOS), and synbiotics share similar efficacy in attenuating cardiac mitochondrial dysfunction in obese-insulin resistant rats...
March 20, 2018: Nutrition
https://www.readbyqxmd.com/read/29705426/potential-probiotic-characterization-of-lactobacillus-reuteri-from-traditional-chinese-highland-barley-wine-and-application-for-room-temperature-storage-drinkable-yogurt
#16
Su Chen, Lin Chen, Lie Chen, Xueliang Ren, Hongjuan Ge, Baolei Li, Guanghui Ma, Xueqin Ke, Jun Zhu, Li Li, Yuhong Feng, Yanjun Li
The aim of this study was to select probiotic strains that could be used in drinkable yogurt to yield viable cells following storage at room temperature (RT). The uniquely high altitude conditions in Tibet and the alcoholic environment of certain products, such as the highland barley wine homemade in Tibet, may induce unusual characteristics of microbial strains. A total of 27 lactic acid bacteria were isolated from homemade highland barley wines. One strain, Lactobacillus reuteri WHH1689, demonstrated no ability for lactose utilization, exhibited a high survival rate during storage at RT in drinkable yogurts, and produced very weak post-acidification...
April 25, 2018: Journal of Dairy Science
https://www.readbyqxmd.com/read/29696746/new-lactic-acid-bacteria-for-skin-health-via-oral-intake-of-heat-killed-or-live-cells
#17
REVIEW
Hiromi Kimoto-Nira
Lactic acid bacteria play an essential role in the food industry in the manufacture of many fermented products (cheese, yogurt, fermented vegetables, etc.). Application of these organisms is now being extended to the area of health improvement, as their probiotic activities become known. Probiotics are defined as viable microorganisms that exert a beneficial effect on the health of the host when they are ingested in sufficient quantity. Lactic acid bacteria and bifidobacteria isolated from the human intestine are the most common probiotics used for human consumption...
June 2018: Animal Science Journal, Nihon Chikusan Gakkaihō
https://www.readbyqxmd.com/read/29693757/adjunctive-probiotic-microorganisms-to-prevent-rehospitalization-in-patients-with-acute-mania-a-randomized-controlled-trial
#18
Faith Dickerson, Maria Adamos, Emily Katsafanas, Sunil Khushalani, Andrea Origoni, Christina Savage, Lucy Schweinfurth, Cassie Stallings, Kevin Sweeney, Joshana Goga, Robert H Yolken
OBJECTIVE: Immunological abnormalities play a role in the pathophysiology of mania and have been associated with relapse. Probiotic organisms such as Lactobacilli and Bifidobacteria modulate inflammation in humans and animal models. The trial examined whether the administration of probiotic organisms prevents psychiatric rehospitalizations in patients recently discharged following hospitalization for mania. METHODS: Patients hospitalized for mania (N = 66) were randomized after discharge to receive 24 weeks of adjunctive probiotics (Lactobacillus rhamnosus strain GG and Bifidobacterium animalis subsp...
April 25, 2018: Bipolar Disorders
https://www.readbyqxmd.com/read/29688915/clinical-and-microbiological-effect-of-a-multispecies-probiotic-supplementation-in-celiac-patients-with-persistent-ibs-type-symptoms-a-randomized-double-blind-placebo-controlled-multicenter-trial
#19
Ruggiero Francavilla, Maria Piccolo, Antonio Francavilla, Lorenzo Polimeno, Francesco Semeraro, Fernanda Cristofori, Stefania Castellaneta, Michele Barone, Flavia Indrio, Marco Gobbetti, Maria De Angelis
GOALS: The goals of this study were to evaluate the efficacy and safety of a probiotic mixture in patients with celiac disease (CD) with irritable bowel syndrome (IBS)-type symptoms despite a strict gluten-free diet (GFD). BACKGROUND: About 30% of patients with CD adherent to a GFD suffer from IBS-type symptoms; a possible cause resides in the imbalances of the intestinal microbiota in CD. Probiotics may represent a potential treatment. STUDY: CD patients with IBS-type symptoms entered a prospective, double-blind, randomized placebo-controlled study...
April 23, 2018: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/29684056/bifidobacteria-isolated-from-vaginal-and-gut-microbiomes-are-indistinguishable-by-comparative-genomics
#20
Aline C Freitas, Janet E Hill
Bifidobacteria colonize the human gastrointestinal tract, vagina, oral cavity and breast milk. They influence human physiology and nutrition through health-promoting effects, play an important role as primary colonizers of the newborn gut, and contribute to vaginal microbiome homeostasis by producing lactic acid. Nevertheless, the mechanisms by which bifidobacteria are transmitted from mother to infant remains in discussion. Moreover, studies have suggested that Bifidobacterium spp. have specializations for gut colonization, but comparisons of strains of the same bifidobacteria species from different body sites are lacking...
2018: PloS One
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