Soudeh Ghafouri-Fard, Tayyebeh Khoshbakht, Bashdar Mahmud Hussen, Aria Baniahmad, Mohammad Taheri, Majid Mokhtari
PCGEM1 Prostate-Specific Transcript is an lncRNA participating in the carcinogenesis process in different tissues. The gene coding this lncRNA is located on chr2:192,749,008-192,783,952 (GRCh38/hg38), plus strand and has 34,945 bases. In addition to prostate cancer, it has been shown to influence progression of cervical, endometrial, gastric, ovarian, hepatocellular and renal cancers. Functionally, PCGEM1 regulates activity of a number of molecular axes, namely miR-642a-5p/LGMN, miR-182/FBXW11, miR-129-5p/STAT3, miR-129-5p/P4HA2, miR-433-3p/FGF2, miR-539-5p/CDK6, miR-129-5p/ETV1, miR-433-3p/WTAP, miR-590-3p/SOX11 and miR-506-3p/TRIAP1...
November 15, 2022: Pathology, Research and Practice