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https://www.readbyqxmd.com/read/28527278/-drug-rash-with-eosinophilia-and-systemic-symptoms-syndrome-induced-by-carbamazepine-case-report
#1
Jorge Alonso Marín, Mayra Alexandra Ortega, Isaura Pilar Sánchez, José Armando Pacheco
Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome is a hypersensitivity reaction associated with a variety of drugs, mainly anticonvulsants, which is characterized by systemic symptoms and erythematous lesions, common to other toxicodermas. It is an uncommon clinical entity that requires a high suspicion by clinical staff given its varied initial presentation, and the fact that symptoms can overlap with those of other adverse cutaneous reactions to drugs. Without early diagnosis and appropriate treatment, mortality increases...
June 1, 2017: Biomédica: Revista del Instituto Nacional de Salud
https://www.readbyqxmd.com/read/28526427/atypical-presentations-of-cutaneous-leishmaniasis-a-systematic-review
#2
REVIEW
Camilla Barros Meireles, Laís Chaves Maia, Gustavo Coelho Soares, Ilara Parente Pinheiro Teodoro, Maria do Socorro Vieira Gadelha, Cláudio Gleidiston Lima da Silva, Marcos Antonio Pereira de Lima
Cutaneous Leishmaniasis (CL) is endemic in 88 countries, showing relevant prevalences. The aim of this study was to perform a systematic review on atypical lesions of CL around the world, addressing clinico-epidemiological, immunological and therapeutic aspects. A search of the literature was conducted via electronic databases Scopus and PubMed for articles published between 2010 and 2015. The search terms browsed were "cutaneous leishmaniasis", "atypical" and "unusual". Based on the eligibility criteria, 34 out of 122 articles were included in the final sample...
May 16, 2017: Acta Tropica
https://www.readbyqxmd.com/read/28521835/adult-autoimmune-enteropathy-presenting-initially-with-acquired-acrodermatitis-enteropathica-a-case-report
#3
Erina Lie, Sarah Sung, Steven Hoseong Yang
BACKGROUND: Acrodermatitis enteropathica (AE) is a rare dermatitis secondary to zinc deficiency most commonly seen as an inherited disease in infants. In the last decade, increased number of reports have been published on the acquired form that presents in adulthood. Unlike its inherited counterpart, acquired AE (AAE) is often secondary to underlying pathologic or iatrogenic etiologies that interfere with nutritional absorption, such as inflammatory bowel disease or alcoholism. Various gastrointestinal pathologies have been associated with AAE, but there is currently no report on its association with adult autoimmune enteropathy (AIE), a rare gastrointestinal disorder commonly seen in infants, with limited cases reported in adults...
May 18, 2017: BMC Dermatology
https://www.readbyqxmd.com/read/28515991/non-follicular-milky-globules-dermoscopy-saves-the-day
#4
Abhijeet K Jha, Sidharth Sonthalia, Aimilios Lallas
Acute generalized exanthematous pustulosis (AGEP) is a rare severe cutaneous adverse reaction caused mostly by medication. Early diagnosis is important as initiation of supportive treatment and avoidance of drug is of prime importance. A young male presented with an erythematous rash after taking diclofenac for pain. Polarized dermoscopy revealed milky globules on a uniform reddish background sparing the follicles, which confirmed the diagnosis of AGEP.
April 2017: Dermatology Practical & Conceptual
https://www.readbyqxmd.com/read/28515564/delayed-stevens-johnson-syndrome-secondary-to-the-use-of-lamotrigine-in-bipolar-mood-disorder
#5
Kunal Kishor Jha, Durgesh Prasad Chaudhary, Tshristi Rijal, Semanta Dahal
Lamotrigine is a mood-stabilizing drug used in maintenance treatment of bipolar I disease. There are adverse effects with lamotrigine such as a headache, blurred vision, diplopia, somnolence, ataxia, dizziness, rash, Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis. SJS is a life-threatening, blistering mucocutaneous disease. SJS is characterized by the presence of flat, diffuse erythematous maculopapular rashes with the involvement of <10% of the body surface area. Standard trigger is drugs including anticonvulsants, antibiotics, and Mycoplasma pneumoniae infection...
March 2017: Indian Journal of Psychological Medicine
https://www.readbyqxmd.com/read/28514468/disseminated-erythematous-crusted-and-pustular-plaques-on-the-trunk
#6
Enrique Rodríguez-Lomba, Pedro Vilas-Boas, Ricardo Suárez-Fernández
No abstract text is available yet for this article.
May 17, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/28512644/analysis-of-serum-cytokines-and-single-nucleotide-polymorphisms-of-sod1-sod2-and-cat-in-erysipelas-patients
#7
Charles C Emene, Irina E Kravchenko, Gulnaz I Aibatova, Albert A Rizvanov
Increased free radical production had been documented in group A (β-hemolytic) streptococcus infection cases. Comparing 71 erysipelas patients to 55 age-matched healthy individuals, we sought for CAT, SOD1, and SOD2 single polymorphism mutation (SNPs) interactions with erysipelas' predisposition and serum cytokine levels in the acute and recovery phases of erysipelas infection. Whereas female patients had a higher predisposition to erysipelas, male patients were prone to having a facial localization of the infection...
2017: Journal of Immunology Research
https://www.readbyqxmd.com/read/28512370/occupational-contact-allergy-to-omeprazole-and-ranitidine
#8
Inmaculada Herrera-Mozo, Pere Sanz-Gallen, Gabriel Martí-Amengual
Omeprazole is a proton pump inhibition and ranitidine is an H2 histamine receptor antagonist widely used in the treatment of gastroesophageal reflex disease, peptic ulcer disease, Zollinger-Ellison syndrome and as a protector of the gastric mucosae. We report a case of occupational contact allergy to omeprazole and ranitidine. A 48-year-old man, with no pre-existing history of atopy or lifestyle factors. He neither had any medical history of consumption of drugs such as ranitidine and omeprazole. He worked for 19 months in the pharmaceutical company that manufactured ranitidine base...
May 16, 2017: Medycyna Pracy
https://www.readbyqxmd.com/read/28511237/performance-of-a-fully-disposable-digital-single-operator-cholangiopancreatoscope
#9
Raj J Shah, Isaac Raijman, Brian Brauer, Bora Gumustop, Douglas K Pleskow
Background and study aim Our aim was to evaluate the first use in humans of a new, single-use, digital, single-operator intraductal cholangiopancreatoscopy system (IDCP). Patients and methods Data were collected retrospectively from four US institutions between February 2015 and April 2015. The visual impression of neoplasia or benign findings with IDCP was determined by the performing endoscopist. High grade dysplasia, intraductal papillary mucinous neoplasm, neuroendocrine tumor, and malignancy were categorized as neoplasia...
May 16, 2017: Endoscopy
https://www.readbyqxmd.com/read/28507830/dermatitis-due-to-paederus-colombinus-report-of-an-epidemic-outbreak-of-68-cases-in-the-province-of-darien-panama
#10
Lorenzo Cáceres, Jose A Suarez, Carmela Jackman, Amanda Galbster, Roberto Miranda, Ingrid Murgas, Juan Pascale, Nestor Sosa, Alfonso J Rodriguez-Morales
INTRODUCTION: Contact dermatitis due to Paederus is a particular form of accident by animal contact. It is characterized by the sudden onset of erythematous and vesicular lesions with burning sensation on exposed areas of the body. The aim of this study was to describe the epidemiological and clinical findings of an outbreak of Paederus dermatitis in Panama. METHODS: Clinical and epidemiological findings of an outbreak of contact dermatitis caused by Paederus sp...
April 12, 2017: Curēus
https://www.readbyqxmd.com/read/28501827/a-confirmed-case-of-sugammadex-induced-anaphylaxis-in-a-uk-hospital
#11
Robert O'Donnell, Jack Hammond, Sam Soltanifar
We report the first published case of confirmed anaphylaxis to sugammadex in a UK hospital. The patient was given a bolus of sugammadex at the end of surgery. Four minutes later, he developed hypotension and a widespread erythematous rash. Multiple epinephrine boluses were administered and a continuous intravenous infusion of epinephrine commenced. The patient later reported auditory awareness, which occurred while the diagnosis of anaphylaxis was being made and initial treatment initiated. Serial serum tryptase levels were consistent with a type I hypersensitivity reaction...
May 13, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28501271/virtual-cystoscopy-computed-tomography-urography-and-optical-cystoscopy-for-the-detection-and-follow-up-for-bladder-cancer
#12
D Ibáñez Muñoz, I Quintana Martínez, A Fernández Militino, D Sánchez Zalabardo, L Sarria Octavio de Toledo, R Cozcolluela Cabrejas
OBJECTIVES: To evaluate the utility of virtual cystoscopy (VC) performed with CT urography in patients being studied under gross hematuria or patients being followed-up after a previous bladder cancer and compare the results with those obtained with gold standard technique (optical cystoscopy). METHODS: Retrospective study of 117 patients who were referred for VC by the Urology Department between May 2014 and May 2015. Those patients presented with gross hematuria or they were previously treated patients from bladder cancer being followed up...
May 10, 2017: Radiología
https://www.readbyqxmd.com/read/28494855/a-complication-of-wet-cupping-therapy-vesiculobullous-plaque-on-an-erythematous-base
#13
Ali Ramazan Benli, Habibullah Aktas
No abstract text is available yet for this article.
May 2017: Journal of Integrative Medicine
https://www.readbyqxmd.com/read/28492421/description-of-malignancy-rates-in-childhood-and-adult-onset-systemic-lupus-erythematous-by-proportional-meta-analysis
#14
Priscila Rodrigues da Silva Aoki, Regina El Dib, Clovis Artur Almeida Silva, Claudia Saad Magalhaes
OBJECTIVE: The aim of this study was to describe the malignancy rates in childhood and adult-onset systemic lupus erythematous (SLE) by proportional meta-analysis. METHODS: Two reviewers screened data from PubMed (1966-2015), EMBASE (1980-2015), and LILACS (1982-2015) for SLE-associated malignancy. Proportional meta-analysis with a random-effects model and 95% confidence intervals (CIs) were calculated according to SLE onset age and mean follow-up time. Statistical difference was defined by 95% CI overlap...
May 11, 2017: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
https://www.readbyqxmd.com/read/28491441/successful-treatment-of-vaginal-malakoplakia-in-a-young-cat
#15
Ryan P Cattin, Michael R Hardcastle, Kenneth W Simpson
CASE SUMMARY: A 3-year-old, female, spayed, domestic shorthair cat presented for dysuria and haematuria, unresponsive to antibiotic treatment. A small, fleshy, erythematous mass protruded from the vaginal vault. Ultrasound identified a vaginal mass effect with mixed echogenicity measuring in excess of 3 cm. Vaginoscopy confirmed an extensive, fleshy, irregular mass that was characterised histologically as pyogranulomatous vaginitis, with periodic acid-Schiff-positive macrophages containing gram-negative bacteria...
July 2016: JFMS Open Rep
https://www.readbyqxmd.com/read/28491431/hyperinsulinaemic-hypoglycaemic-syndrome-due-to-acquired-nesidioblastosis-in-a-cat
#16
Lydia E Hambrook, Amanda A Ciavarella, Judith S Nimmo, Julie Wayne
Case summary A 6-year-old, neutered female British Shorthair cat presented with acute-onset weakness and mental dullness. Initially the cat was mildly hyperglycaemic (9.9 mmol/l; reference interval [RI] 3.3-6.7 mmol/l). Over the following 12 h the cat developed central blindness, tremors, intermittent seizures and opisthotonus. Repeat blood sampling revealed a marked hypoglycaemia (0.8 mmol/l). Insulin level (performed on a serum sample collected while the cat was hypoglycaemic) was inappropriately elevated (1575 mIU/l; RI 10-80 mIU/l)...
July 2016: JFMS Open Rep
https://www.readbyqxmd.com/read/28488124/hypomyopathic-dermatomyositis-associated-with-interstitial-lung-disease-and-good-response-to-mycophenolate-mofetil-case-based-review
#17
REVIEW
Roberta Vilela Lopes Koyama, Tiago Kiyoshi Kitabayashi Braga, George Alberto da Silva Dias, Satomi Fujihara, Hellen Thais Fuzii, Gilberto Toshimitsu Yoshikawa
Hypomyopathic dermatomyositis (HDM) is a rare form of dermatomyositis (DM). Interstitial lung disease (ILD) associated with clinically amyopathic DM (CADM-ILD) or hypomyopathic DM (HDM-ILD) is a rare condition with a more unfavorable prognosis than ILD associated with classic DM (CDM-ILD). There is no effective treatment for HDM-ILD. A 62-year-old woman with a 6-month history of chronic polyarthritis and myalgia presented skin lesions characteristic of DM (erythematous lesion on extensor surface of elbows, Gottron's papules, V-neck sign) with no clinical muscle impairment (global muscle strength: grade 5)...
May 9, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28484350/prevalence-of-chronic-erythematous-candidiasis-in-lebanese-denture-wearers-a-clinico-microbiological-study
#18
Georges Aoun, Antoine Berberi
OBJECTIVE: Chronic erythematous candidiasis also known as denture-related stomatitis refers to inflammatory changes of the denture-bearing mucosa. The aim of this study was to evaluate the prevalence of chronic erythematous candidiasis in a Lebanese population using clinical and microbiological examinations. MATERIALS AND METHODS: Ninety-eight patients wearing full acrylic maxillary denture (50 women and 48 men) were included in this study. A clinical oral assessment and a microbiological exam using swab samples collected from the palate of these patients were performed and the data obtained were analyzed statistically...
March 2017: Materia Socio-medica
https://www.readbyqxmd.com/read/28482929/ivermectin-induced-steven-johnsons-syndrome-case-report
#19
Desmond Aroke, Diego Nitcheu Tchouakam, Alexis Tazinya Awungia, Sylvester Yari Mapoh, Stewart Ndutard Ngassa, Benjamin Momo Kadia
BACKGROUND: Stevens-Johnson syndrome is one of the manifestations of mucocutaneous adverse drug reactions. Although antimicrobials are responsible for greater than 50% of these adverse drug reactions, there is no documented case implicating ivermectin as the culprit. A 38 year old adult Cameroonian male presented to our health facility with facial rash, painful oral sores, black eschars on lips and red tearing eyes 3 days following ingestion of ivermectin received during a nationwide anti-filarial campaign...
May 8, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28480635/drug-induced-cutaneous-lupus-erythematosus-after-immunoglobulin-treatment-in-chronic-inflammatory-demyelinating-polyneuropathy-a-case-series
#20
Max E Adrichem, Markus V Starink, Ester Mm van Leeuwen, Christine Kramer, Ivo N van Schaik, Filip Eftimov
We describe six patients with cutaneous lupus erythematosus (cLE) during immunoglobulin G (IgG) treatment. Five patients were diagnosed with chronic inflammatory demyelinating polyneuropathy (CIDP) and one patient with possible CIDP. Five patients received intravenous immunoglobulin (IVIg) and one patient subcutaneous immunoglobulin (SCIg). Skin lesions were systematically assessed by a dermatologist including skin biopsies. Patients showed disseminated erythematous plaques on several parts of the body with predominance of the chest and face...
May 8, 2017: Journal of the Peripheral Nervous System: JPNS
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