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https://www.readbyqxmd.com/read/28641548/pediatric-cutaneous-graft-versus-host-disease-a-review
#1
Connie R Shi, Jennifer T Huang, Vinod E Nambudiri
BACKGROUND: Graft versus host disease (GVHD) is a significant complication following hematopoietic stem cell transplantation in the pediatric population. The most common clinical manifestation of GVHD is in the skin. This article will present a review of key concepts related to pediatric cutaneous GVHD, including pathophysiology, clinical epidemiology, diagnosis, and treatment options. GVHD is an immune-mediated process characterized by an inflammatory immune response in acute GVHD and mixed inflammatory and fibrotic states in chronic GVHD...
June 14, 2017: Current Pediatric Reviews
https://www.readbyqxmd.com/read/28640502/erythematous-plaques-of-the-vulvo-perineal-region-diagnostic-role-of-dermatoscopy
#2
Alessia Barisani, Emi Dika, Pier Alessandro Fanti, Annalisa Patrizi, Sabina Vaccari
No abstract text is available yet for this article.
June 22, 2017: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
https://www.readbyqxmd.com/read/28639958/pediatric-jellyfish-envenomation-in-the-mediterranean-sea
#3
Miguel Glatstein, Dikla Adir, Bella Galil, Dennis Scolnik, Ayelet Rimon, Dikla Pivko-Levy, Christopher Hoyte
BACKGROUND: Several species of jellyfish native to the western Indian Ocean have entered the Mediterranean Sea through the Suez Canal. Since the late 1980s, each summer Rhopilema nomadica forms swarms as long as 100 km in the southeastern Levant and since the millennium aggregations of additional nonnative jellyfish have been sighted. The aim of this study was to evaluate children seen in the emergency department after jellyfish envenomations and to establish patterns of toxicity associated with this organism...
June 20, 2017: European Journal of Emergency Medicine: Official Journal of the European Society for Emergency Medicine
https://www.readbyqxmd.com/read/28639722/european-guideline-for-the-management-of-scabies
#4
C M Salavastru, O Chosidow, M J Boffa, M Janier, G S Tiplica
Scabies is caused by Sarcoptes scabiei var. hominis. The disease can be sexually transmitted. Patients' main complaint is nocturnal itch. Disseminated, excoriated, erythematous papules are usually seen on the anterior trunk and limbs. Crusted scabies occurs in immunocompromised hosts and may be associated with reduced or absent pruritus. Recommended treatments are permethrin 5% cream, oral ivermectin and benzyl benzoate 25% lotion. Alternative treatments are malathion 0.5% aqueous lotion, ivermectin 1% lotion and sulphur 6-33% cream, ointment or lotion...
June 22, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28639713/rosacea-in-black-south-africans-with-skin-phototypes-v-and-vi
#5
N C Dlova, A Mosam
Rosacea is a chronic facial dermatosis considered to affect primarily white patients with light phototype skin, and is poorly documented in black patients. The aim of this study was to document the clinical features of rosacea in patients with phototypes V and VI. An 8-year retrospective chart review of patients with a clinical and histological diagnosis of rosacea or acne rosacea was undertaken. Of 6700 patients, 15 (0.2%) had rosacea. All were of African descent with skin phototype V or VI. Mean age was 47 years, and female : male ratio was 14 : 1...
June 22, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28633745/carcinoma-hemorrhagiectoides-case-report-of-an-uncommon-presentation-of-cutaneous-metastatic-breast-carcinoma
#6
Roberto Cullen Aravena, Daniella Cullen Aravena, Margarita Jo Velasco, Alejandra Queirolo González, Luis Requena
In most cases, cutaneous metastases develop after the diagnosis of the primary internal malignancy has been established, but sometimes they can be discovered earlier or simultaneously. We describe a case of a 90-year-old woman who presented to the emergency room in poor general condition, with cutaneous lesions characterized by hot, infiltrated, violaceous and erythematous plaques involving the left chest wall. The clinical and histopathological findings were consistent with the recently described variant of inflammatory cutaneous metastatic carcinoma named carcinoma hemorrhagiectoides...
June 15, 2017: Dermatology Online Journal
https://www.readbyqxmd.com/read/28633739/autoimmune-progesterone-dermatitis-presenting-as-fixed-drug-eruption-a-case-report
#7
Raya Mokhtari, Mozhdeh Sepaskhah, Fatemeh Sari Aslani, Ladan Dastgheib
Autoimmune progesterone dermatitis (APD) is a rare disorder characterized by periodic skin lesions that erupt during the luteal phase of the menstrual cycle. Clinical manifestations of APD is caused by an unusual allergy to progesterone and has a wide range of clinical manifestations from eczema and urticaria to angioedema and erythema multiforme. A 46-year-old woman described recurrent, round erythematous plaques on the lower lip, both forearms and buttocks. These skin eruptions waxed and waned for 10 months, reoccurring 3-4 days before menstruation...
June 15, 2017: Dermatology Online Journal
https://www.readbyqxmd.com/read/28633736/klippel-trenauney-syndrome-with-axillary-hyperhidrosis
#8
Yeun Jina Lim, David Rosmarin, Giannoula Klement, Shiu-Chung Au
Klippel-Trenaunay syndrome (KTS) is a rare, clinically variable congenital disorder involving capillary malformations, soft tissue or bone hypertrophy, and venous malformations or varicose veins. We report a 28-year-old man who presented with a hypertrophic right arm as well as markedly increased ipsilateral axillary hyperhidrosis and erythematous patches on the back, chest, and arm. This case of KTS is unusual because our patient presented with a markedly increased unilateral axillary hyperhidrosis ipsilateral to the hypertrophic limb...
June 15, 2017: Dermatology Online Journal
https://www.readbyqxmd.com/read/28632887/pushing-the-edge-of-dermoscopy-in-new-directions-entomodermoscopy-of-trombicula-autumnalis
#9
Nicola di Meo, Anna Campanati, Mattia Fadel, Giusto Trevisano
Dermatologists are often faced with the challenge of patients presenting with non specific symptoms such as itching and or erythema. These symptoms may be attributed to a number of diseases, many of which are trivial, and others even life-threatening. In order to establish the correct diagnosis, dermatologists must rely on good diagnostic tools and knowledge. Dermoscopy was introduced mainly for inspection of pigmented lesions, but its use has now also spread to non-melanoma skin cancer, inflammatory diseases, and almost any skin disease...
June 2017: Acta Dermatovenerologica Alpina, Panonica, et Adriatica
https://www.readbyqxmd.com/read/28632799/recalcitrant-solitary-erythematous-scaly-patch-on-the-foot
#10
Ryan Gillihan, Chi Tran, Garth R Fraga, Ryan Fischer
No abstract text is available yet for this article.
May 2017: Cutis; Cutaneous Medicine for the Practitioner
https://www.readbyqxmd.com/read/28632507/tibialis-posterior-tenosynovitis-a-unique-musculoskeletal-manifestation-of-gout
#11
Peter Shupper, Todd P Stitik
Extra-articular manifestations of gout can present in several ways, including tenosynovitis. We present a rare case of acute tibialis posterior gouty tenosynovitis. An 82-year-old man with a history of well-controlled gout presented with acute onset of left ankle pain, occurring without inciting event. The medial ankle was slightly erythematous with moderate dorsal-medial swelling and mild dorsal-lateral swelling, with severe tenderness to palpation over the medial retro-malleolar region. Range of motion and manual muscle testing were pain limited throughout...
June 20, 2017: American Journal of Physical Medicine & Rehabilitation
https://www.readbyqxmd.com/read/28627100/subcutaneous-extraskeletal-osteosarcoma-in-a-metatarsal-footpad-in-a-cat
#12
Ramón Almela, Wolf von Bomhard, Agustina Ansón, Ursula Mayer
BACKGROUND: Extraskeletal osteosarcomas (ESOSAs) are rare neoplasms in humans and animals. In cats, ESOSA has been reported to arise from orbital, ocular, intestinal, mammary and subcutaneous locations. Subcutaneous ESOSA occurs most commonly at sites used for vaccination including interscapular, dorsal lumbar or thigh areas. Previous reports of feline cases have not documented the use of advanced diagnostic imaging to exclude a primary bone tumour. OBJECTIVE: To describe the clinicopathological and advanced imaging findings of a subcutaneous ESOSA occurring in a metatarsal footpad of a cat and to report the one year follow-up status...
June 18, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28627005/serum-interleukin-37-a-new-player-in-lupus-nephritis
#13
Marwa G Tawfik, Samah I Nasef, Hanan H Omar, Mona S Ghaly
INTRODUCTION: Interleukin-37 (IL-37) has been proved to be a fundamental natural suppressor of innate immunity and inflammatory responses in autoimmune diseases such as systemic lupus erythematous (SLE). The purpose of this study was to assess serum IL-37 level in SLE patients and its correlation with disease activity and clinical and laboratory manifestations of SLE patients. PATIENTS/METHODS: The serum level of IL-37 was assessed and analyzed in 100 SLE patients and 50 healthy controls by using enzyme-linked immunosorbent assay (ELISA)...
June 19, 2017: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/28611630/sweet-s-syndrome-successfully-treated-with-granulocyte-and-monocyte-adsorption-apheresis
#14
Asami Fujii, Yoko Mizutani, Yuki Hattori, Tomoko Takahashi, Hidenori Ohnishi, Shozo Yoshida, Mariko Seishima
Sweet's syndrome is a neutrophilic dermatosis characterized by an abrupt onset of painful erythematous lesions showing neutrophilic infiltrates in the dermis. Fever and an elevated neutrophil level are generally observed. Sweet's syndrome may be idiopathic, malignancy-associated, or drug-induced (mainly involving granulocyte colony-stimulating factor (G-CSF) administration). Although systemic corticosteroids are usually effective, the symptoms of Sweet's syndrome recur in some refractory cases. Herein, we report a case of a 55-year-old Japanese woman with recurrent symptoms of fever (>39°C) and painful erythematous lesions on her four extremities, trunk, and neck...
May 2017: Case Reports in Dermatology
https://www.readbyqxmd.com/read/28611625/necrolytic-acral-erythema-in-seronegative-hepatitis-c
#15
Ploychompoo Srisuwanwattana, Vasanop Vachiramon
Necrolytic acral erythema (NAE) is a distinctive skin disorder. The exact cause and pathogenesis is still unclear. Most studies report an association of NAE with hepatitis C virus (HCV) infection. We report a 64-year-old woman who presented with chronic mildly pruritic brownish to erythematous rashes on both lateral malleoli for 7 months. The clinical and histopathological findings were compatible with NAE. However, the serologic marker for HCV was negative.
January 2017: Case Reports in Dermatology
https://www.readbyqxmd.com/read/28610589/high-sensitivity-cardiac-troponin-t-is-a-biomarker-for-atherosclerosis-in-systemic-lupus-erythematous-patients-a-cross-sectional-controlled-study
#16
Gillian Divard, Rachid Abbas, Camille Chenevier-Gobeaux, Noémie Chanson, Brigitte Escoubet, Marie-Paule Chauveheid, Antoine Dossier, Thomas Papo, Monique Dehoux, Karim Sacre
BACKGROUND: Cardiovascular disease (CVD) is the main cause of death in systemic lupus erythematous (SLE) patients. The Framingham score underestimates the risk for CVD in this population. Our study aimed to determine whether serum high-sensitivity cardiac troponin T (HS-cTnT) might help to identify SLE patients at risk for CVD. METHODS: The presence of carotid plaques was prospectively assessed by ultrasound in 63 consecutive SLE patients asymptomatic for CVD and 18 controls...
June 13, 2017: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/28606832/extramammary-paget-s-disease-of-the-oral-mucosa-and-perioral-skin
#17
Xiangjian Wang, Lanyan Wu, Xueke Shi, Xin He, Wei Li, Hongmei Zhou
Extramammary Paget's disease (EMPD) is an unusual intraepidermal adenocarcinoma. Only 2 cases of EMPD in the oral mucosa have been reported previously. Here, we present the first report of a rare case of Paget's disease of the oral mucosa and perioral skin with extensive contiguous erythematous and erosive manifestations. Ultimately, the patient was treated with oral thalidomide for 8 weeks. We noticed an improvement with resolution of symptoms. A 3-year follow-up showed no relapse. Thus, this case may provide new insights to clinicians about treatment of EMPD...
May 11, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/28605998/primary-cutaneous-cd4-small-medium-pleomorphic-t-cell-lymphoproliferative-disorder-a-case-series
#18
Martina Maurelli, Chiara Colato, Paolo Gisondi, Giampiero Girolomoni
BACKGROUND: Primary cutaneous CD4(+) small/medium T-cell lymphoproliferative disorder (CD4(+) PCSM-LPD) is defined by a predominance of small- to medium-sized CD4(+) pleomorphic T cells and a favorable clinical course. OBJECTIVE: We performed a retrospective analysis of 6 patients with CD4(+) PCSM-LPD and reviewed the literature to address questions about its diagnosis, treatment, and prognosis. METHODS: Patients were 3 men and 3 women with a median age of 50 years...
June 1, 2017: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/28605051/ultrastructural-aspects-of-primary-anetoderma
#19
Joice Brião Göebel Pinto, Hiram Larangeira de Almeida, Luis Antônio Suíta de Castro, Nara Moreira Rocha
Anetoderma (anetos, Greek for slack) [1], also known as macular atrophy, is a rare elastolytic disorder characterized by circumscribed areas of flaccid skin due to focal loss of dermal elastic tissue, resulting in normochromic or erythematous papules and plaques with a wrinkled and atrophic surface.
June 12, 2017: Journal of Cutaneous Pathology
https://www.readbyqxmd.com/read/28602267/post-reconstruction-dermatitis-of-the-breast
#20
A C Rosen, C Goh, M E Lacouture, B J Mehrara, P G Cordeiro, P L Myskowski
BACKGROUND: Approximately one-third of women diagnosed with breast cancer undergo mastectomy with subsequent implant-based or autogenous tissue-based reconstruction. Potential complications include infection, capsular contracture, and leak or rupture of implants with necessity for explantation. Skin rashes are infrequently described complications of patients who undergo mastectomy with or without reconstruction. METHODS: A retrospective analysis of breast cancer patients referred to the Dermatology Service for diagnosis and management of a rash post-mastectomy and expander or implant placement or transverse rectus abdominis myocutaneous (TRAM) flap reconstruction was performed...
May 20, 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
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