keyword
https://read.qxmd.com/read/38178864/real-life-experience-with-sonidegib-for-locally-advanced-basosquamous-carcinoma-a-case-series
#21
Enrico Bocchino, Simone Cappilli, Gerardo Palmisano, Andrea Paradisi, Alfredo Piccerillo, Alessandro Di Stefani, Ketty Peris
INTRODUCTION: Basosquamous carcinoma is an uncommon subtype of basal cell carcinoma (BCC), characterized by aggressive local growth and metastatic potential, that mainly develops on the nose, perinasal area, and ears, representing 1.2-2.7% of all head-neck keratinocyte carcinomas. Although systemic therapy with hedgehog inhibitors (HHIs) represents the first-line medical treatment in advanced BCC, to date, no standard therapy for advanced basosquamous carcinoma has been established. Herein, we reported a case series of patients affected by locally advanced basosquamous carcinomas, who were treated with HHIs...
2024: Case Reports in Dermatology
https://read.qxmd.com/read/38176206/when-inflammation-is-not-just-inflammation-a-review-of-systemic-diseases-of-the-nose-and-sinuses-part-2-granulomatosis-with-polyangiitis-and-eosinophilic-granulomatosis-with-polyangiitis
#22
REVIEW
Samuel J Cler, M Allison Ogden, Nyssa Fox Farrell, Lauren T Roland, Colin E Diffie, John S Schneider
BACKGROUND: Chronic rhinosinusitis is a very common condition. Granulomatosis with polyangiitis (GPA) and eosinophilic granulomatosis with polyangiitis (eGPA) are systemic diseases which can contribute to the development of chronic rhinosinusitis in select patients. OBJECTIVE: Characterize the presenting features, diagnostic criteria, workup, and management of granulomatosis with polyangiitis and eosinophilic granulomatosis with polyangiitis as they are encountered in otolaryngology clinics...
December 18, 2023: American Journal of Otolaryngology
https://read.qxmd.com/read/38145151/plastic-surgery-beware-the-candle-burning-at-both-ends
#23
JOURNAL ARTICLE
Kathryn W Brown, Clayton A Moss, Martin G McCandless, Muntazim Mukit, Marc E Walker
BACKGROUND: Plastic surgery dates back to 800 BC, where forehead flaps were used to reconstruct noses in India. Today, it is one of the most romanticized fields in medicine. Due to the influence of social media, there has never been a larger spotlight. Ironically, this spotlight brings a narrowed perception of the scope of plastic surgery. This study aimed to assess the scope through the eyes of the average American to identify gaps in knowledge to better represent the field. METHODS: A series of questions were developed under survey methodologists and administered by Qualtrics...
December 2023: Plastic and Reconstructive Surgery. Global Open
https://read.qxmd.com/read/38131127/hyaluronic-acid-filler-induced-vascular-occlusion-three-case-reports-and-overview-of-prevention-and-treatment
#24
REVIEW
Rong Wang, Yukun Li, Zhaoxin Li, Haifeng Yao, Zhaohui Zhai
BACKGROUND: Vascular occlusion induced by hyaluronic acid injections is rare, but can lead to severe adverse events, including necrosis, blindness, and cerebral infarction. OBJECTIVE: This study aims to explore methods of reducing the risk of complications such as embolism induced by hyaluronic acid injection, and to study the impact of comprehensive systematic treatment on the prognosis of patients with hyaluronic acid embolism. METHODS: The clinical data of three female patients with vascular occlusion due to hyaluronic acid injection was analyzed...
December 22, 2023: Journal of Cosmetic Dermatology
https://read.qxmd.com/read/38108112/natural-orifice-specimen-extraction-surgery-versus-small-incision-assisted-laparoscopic-radical-right-hemicolectomy
#25
REVIEW
Mengqin Yu, Zhenghao Cai, Haitao Zhou, Abraham Fingerhut, Zirui He, Pei Xue, Haiqin Song, Xiao Yang, Xi Cheng, Sen Zhang, Ximo Xu, Hao Zhong, Naijipu Abuduaini, Jingyi Liu, Xishan Wang, Bo Feng
Conventional laparoscopic-assisted right hemicolectomy requires a small abdominal incision to extract the specimen, which becomes an important source of postoperative complications and impairs perioperative experience. Transvaginal natural orifice specimen extraction surgery (NOSES VIIIA) avoids this small incision by extracting the specimen through the vagina. Here we describe the design of a multicenter, open-label, parallel, noninferior, phase III randomized controlled trial (NCT05495048). The aim of this study is to confirm that the NOSES VIIIA procedure is not inferior to small-incision assisted right hemicolectomy in long-term oncological efficacy...
December 18, 2023: Future Oncology
https://read.qxmd.com/read/37984528/assessment-of-therapeutic-efficacy-in-seven-cases-of-basal-cell-carcinoma-in-the-ear-and-nose-region-treated-with-new-surgical-excision-and-immediate-photodynamic-therapy
#26
JOURNAL ARTICLE
Ping Yang, Beilei He, Jianbo Zhong, Xingyun Zhao, Zhangyu Bu
BACKGROUND: Basal cell carcinoma (BCC) is the most prevalent non-melanoma skin tumor. It commonly affects exposed areas. Currently, surgical resection is considered the primary approach for BCC treatment. However, BCC frequently affects exposed facial areas, leading to visible scars after surgery. PDT has garnered increasing recent attention, demonstrating superior efficacy and favorable cosmetic outcomes for superficial BCCs. However, it shows limited treatment effectiveness for deep-seated tumors...
November 18, 2023: Photodiagnosis and Photodynamic Therapy
https://read.qxmd.com/read/37892665/using-generative-artificial-intelligence-tools-in-cosmetic-surgery-a-study-on-rhinoplasty-facelifts-and-blepharoplasty-procedures
#27
JOURNAL ARTICLE
Bryan Lim, Ishith Seth, Skyler Kah, Foti Sofiadellis, Richard J Ross, Warren M Rozen, Roberto Cuomo
Artificial intelligence (AI), notably Generative Adversarial Networks, has the potential to transform medical and patient education. Leveraging GANs in medical fields, especially cosmetic surgery, provides a plethora of benefits, including upholding patient confidentiality, ensuring broad exposure to diverse patient scenarios, and democratizing medical education. This study investigated the capacity of AI models, DALL-E 2, Midjourney, and Blue Willow, to generate realistic images pertinent to cosmetic surgery...
October 14, 2023: Journal of Clinical Medicine
https://read.qxmd.com/read/37873992/-not-available
#28
JOURNAL ARTICLE
Jeppe Hjembæk-Brandt, Marianne Kromann Nielsen, Preben Homøe
Injuries to the cartilaginous structures of the nose can arise after minor trauma and without a concomitant nasal fracture. They are diagnosed with a thorough clinical examination and can, if not diagnosed and treated in the acute phase, result in nasal/septal deformation, saddle nose or abscess formation with subsequent intracranial spreading of the infection. Even with proper treatment in the acute phase, the cartilage often heals with deviation. This can result in functional and cosmetic problems which may require later reconstructive surgery, as argued in this review...
September 25, 2023: Ugeskrift for Laeger
https://read.qxmd.com/read/37846655/ultrasound-assessment-of-the-nose-vasculature-a-review-of-the-common-method-of-non-surgical-filler-based-rhinoplasty
#29
REVIEW
Pantea Shekarriz, Farid Hosseini, Pardis Shojaee
BACKGROUND: With the increasing use of dermal injectable fillers in aesthetic medicine, the popularity of non-surgical filler-based rhinoplasty (NSR) is also growing. While performing this procedure might result in certain vascular complications, injecting deep into the midline of the nose is commonly considered the safest method for blind primary NSR. AIMS: In this study, we challenged the common NSR method with a Doppler ultrasound study of the nose. PATIENTS/METHODS: The vascular pattern of the common zones of the NSR procedure (radix and nasal tip) of 21 Iranian women were investigated by using a 14 MHz Doppler handheld ultrasound device (Silarious L14PS)...
March 2024: Journal of Cosmetic Dermatology
https://read.qxmd.com/read/37839388/ethnic-rhinoplasty-preliminary-results-of-our-technique-in-the-pursuit-of-the-harmonious-nose
#30
JOURNAL ARTICLE
Mirco Pozzi, Cinthia Fàdel, Alberto Bolletta, Roberto Cuomo, Carlos Weck Roxo
INTRODUCTION: According to the American Society of Plastic Surgery, cosmetic surgery procedures for "ethnic patients" are annually increasing. Ethnic rhinoplasty traditionally represents a difficult challenge for plastic surgeons. Herein, we describe our personal technique to ethnic rhinoplasty to achieve a harmonious nose maintaining the characteristics of individual ethnicity and identity. MATERIALS AND METHODS: In this study, we retrospectively reviewed ethnic patients treated with rhinoplasty at our institution between January 2019 and October 2022...
December 2023: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://read.qxmd.com/read/37838232/treatment-of-nasal-squamous-cell-carcinoma-with-combination-of-surgery-and-photodynamic-therapy
#31
Meng Cao, Liming Huang, Wenbo Bu, Fang Fang, Tong Lin, Yan Wang
Cutaneous squamous cell carcinoma (cSCC) is a common malignant skin tumor. Some invasive cSCC can cause severe cosmetic damage; therefore, comprehensive measures should be taken. Here, we present a case of a 48-year-old male patient with invasive cSCC on the nose. The lesion recurred twice after excision in the other hospital. After admission, the patient underwent surgical excision; however, the tumor remained because of its deep infiltration, and we left the wound exposed without repair. During the period of open-wound, the patient received 5-aminolevulinic acid-based photodynamic therapy (ALA-PDT) to completely clear the residual tumors, and multipoint biopsies were performed to monitor the tumor remission process...
October 12, 2023: Photodiagnosis and Photodynamic Therapy
https://read.qxmd.com/read/37799442/prospective-clinical-trial-evaluating-the-outcomes-associated-with-the-use-of-fresh-frozen-allograft-cartilage-in-rhinoplasty
#32
JOURNAL ARTICLE
Rou Wan, Joshua P Weissman, Tokoya Williams, Peter J Ullrich, Chitang Joshi, Kristin Huffman, Robert D Galiano
BACKGROUND: There are different types of grafts for rhinoplasty, each with certain advantages and disadvantages. Fresh frozen cadaveric costal allograft (CCA) provides an alternative to rhinoplasties. The aim of this study was to compare the outcomes of fresh frozen CCA and traditional autologous costal cartilage in cosmetic and reconstructive rhinoplasty procedures. METHODS: This is a prospective, single-center, nonrandomized, open-label clinical trial. Objective assessment to evaluate warping, resorption, and displacement of the cartilage was achieved by measuring the differences of standardized values (deviation angle, nasofrontal angle, total facial convexity, nasofacial angle, and nasolabial angle) obtained at 6-months and 12-months postoperative follow-up on standard two-dimensional photographs (Δ = ∣measurement6 - measurement12 ∣)...
October 2023: Plastic and Reconstructive Surgery. Global Open
https://read.qxmd.com/read/37740484/nonsurgical-rhinoplasty-using-the-hyaluronic-acid-filler-vyc-25l-safety-and-patient-satisfaction-in-a-retrospective-analysis-of-492-patients
#33
JOURNAL ARTICLE
Arash Jalali
BACKGROUND: Aesthetic treatment of the nose with hyaluronic acid (HA) fillers is increasingly popular but carries a small risk of major complications. Large patient cohorts are required to better understand this risk. AIMS: To evaluate safety and patient satisfaction in a large series of nonsurgical rhinoplasty treatments with the HA filler, VYC-25L, in "real world" clinical practice. METHODS: This was a retrospective analysis of consecutive adult patients undergoing nonsurgical rhinoplasty with VYC-25L by a single injector between January 2020 and July 2022...
February 2024: Journal of Cosmetic Dermatology
https://read.qxmd.com/read/37682602/topical-188re-ionizing-radiation-therapy-exerts-high-efficacy-in-curing-nonmelanoma-skin-cancer
#34
JOURNAL ARTICLE
Julia K Tietze, Martin Heuschkel, Maila I C Krönert, Jens Kurth, Gesine Bandow, Gregor Ojak, Pavel Grünwald, Johanna Isabelle Herold, Alexander Thiem, Miriam Dreßler, Bernd J Krause, Steffen Emmert, Sarah M Schwarzenböck
PURPOSE OF THE REPORT: Nonmelanoma skin cancer (NMSC) is the most frequent malignancy. Surgical intervention is the common treatment but may lead to disappointing results; alternative treatment options are needed. METHODS: In this monocentric pilot study, topical 188Re resin was investigated as a treatment for invasive NMSC up to 3-mm thickness. Twenty-two patients with 40 histologically confirmed NMSCs with a median size of 1.25 cm2 (range, 0.04-16.8 cm2) and a median tumor thickness of 0...
October 1, 2023: Clinical Nuclear Medicine
https://read.qxmd.com/read/37675713/transvaginal-natural-orifice-specimen-extraction-surgery-for-3d-laparoscopic-radical-cystectomy-a-cohort-study
#35
JOURNAL ARTICLE
Liyuan Wu, Qinxin Zhao, Feiya Yang, Mingshuai Wang, Nianzeng Xing
OBJECTIVE: Transvaginal natural orifice specimen extraction surgery (NOSES) has been widely used in laparoscopic surgery due to its benefits. However, laparoscopic radical cystectomy (LRC) with NOSES has rarely been reported. MATERIALS AND METHODS: A retrospective analysis of 25 patients who underwent 3D LRC with NOSES from November 2014 to November 2019 was performed. The clinical and perioperative related data, peri and postoperative complications, and oncologic outcomes were recorded...
August 2023: Journal of Cancer Research and Therapeutics
https://read.qxmd.com/read/37649333/massive-hemorrhage-and-mortality-following-thyroid-radiofrequency-ablation
#36
JOURNAL ARTICLE
Seulki Song, Jin Pyeong Kim
Radiofrequency ablation (RFA) provides a relatively safe and noninvasive option for treating benign thyroid nodules and thyroid cancer that is cosmetically superior to surgery. Following a loss of consciousness 1 h after thyroid RFA, a 56-year-old patient was transferred to the emergency room. Despite undergoing coronary angiography due to 3 cardiac arrests, the results were normal. Although brain, chest, and abdominal computed tomography scans were performed, the emergency physician failed to detect any hematoma formation...
August 30, 2023: Ear, Nose, & Throat Journal
https://read.qxmd.com/read/37649180/a-modified-full-thickness-labial-buccal-rotational-flap-reconstruction-technique-following-bilateral-rostral-maxillectomy-and-nasal-planectomy-for-resection-of-maxillary-tumors-technique-and-results-in-two-dogs
#37
Panagiotis Kokkinos, James Elliott, José C Almansa Ruiz
OBJECTIVE: To describe a naso-facial reconstruction technique following bilateral rostral maxillectomy and its functional and cosmetic outcomes. ANIMALS: Two dogs. STUDY DESIGN: Clinical case series. METHODS: Two dogs were presented with a right rostral maxillary mass. Preoperative biopsy and staging revealed a biologically high-grade and histologically low-grade fibrosarcoma (Hi-Lo FSA). A combined nasal planectomy and radical bilateral rostral maxillectomy was performed sparing the labial/buccal mucocutaneous flaps bilaterally...
August 30, 2023: Veterinary Surgery
https://read.qxmd.com/read/37636654/use-of-paramedian-forehead-flap-in-an-octogenarian-a-case-report
#38
JOURNAL ARTICLE
Amit Saini, Munish Saroch, Richa Mehra, Gaveshna Gargi
Increase in life expectancy has led to increased number of octogenarian and nonagenarians population. These old people have increased chances of developing skin tumours like slow growing basal cell carcinoma on the sun exposed parts of body. Many a times surgeons all over the world are bit conservative in managing these elderly patients and compromise on cosmetic aspects due to very advanced age of these patients. This report is about an 87-year-old female with BCC of nasal dorsum who underwent a major surgical procedure to maintain facial aesthetics...
September 2023: Indian Journal of Otolaryngology and Head and Neck Surgery
https://read.qxmd.com/read/37619608/pediatric-functional-rhinoplasty
#39
JOURNAL ARTICLE
Samantha Shave, Joseph Vella, Binoy Chandy
Surgery on the growing pediatric nose poses many questions regarding the indications and proper timing. Historically, surgeries on the pediatric nose led to facial growth alterations so many urged caution and waiting until skeletal maturity at the age of 18. However, animal studies showed some promise that facial growth may not be affected. Investigations into effects of pediatric sinus surgery and septal surgery on facial growth showed no issues. The external nose is somewhat different in that minor variations potentially can grow to a cosmetic deformity...
December 2023: Facial Plastic Surgery: FPS
https://read.qxmd.com/read/37567568/the-management-of-post-traumatic-nasal-deformities
#40
JOURNAL ARTICLE
Katherine Kao, Tang Ho
Nasal bone fractures are the most common fractures of the facial skeleton and are often accompanied by bony, cartilaginous and soft tissue injury. These injuries are often complex and when untreated or inadequately treated, can lead to post-traumatic nasal deformity. The most common deformities are the crooked nose and the saddle nose. Both deformities may result in significant cosmetic and functional concerns. The treatment of these deformities can be complex, requiring careful evaluation of the nose and thoughtful planning to correct the cosmetic deformity and restore functional integrity...
August 11, 2023: Facial Plastic Surgery: FPS
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