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https://www.readbyqxmd.com/read/28335039/brain-temporal-complexity-in-explaining-the-therapeutic-and-cognitive-effects-of-seizure-therapy
#1
Faranak Farzan, Sravya Atluri, Ye Mei, Sylvain Moreno, Andrea J Levinson, Daniel M Blumberger, Zafiris J Daskalakis
Over 350 million people worldwide suffer from depression, a third of whom are medication-resistant. Seizure therapy remains the most effective treatment in depression, even when many treatments fail. The utility of seizure therapy is limited due to its cognitive side effects and stigma. The biological targets of seizure therapy remain unknown, hindering design of new treatments with comparable efficacy. Seizures impact the brains temporal dynamicity observed through electroencephalography. This dynamicity reflects richness of information processing across distributed brain networks subserving affective and cognitive processes...
March 3, 2017: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/28332236/the-mortality-rate-of-electroconvulsive-therapy-a-systematic-review-and-pooled-analysis
#2
REVIEW
N Tørring, S N Sanghani, G Petrides, C H Kellner, S D Østergaard
OBJECTIVE: Electroconvulsive therapy (ECT) remains underutilized because of fears of cognitive and medical risks, including the risk of death. In this study, we aimed to assess the mortality rate of ECT by means of a systematic review and pooled analysis. METHOD: The study was conducted in adherence with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guideline. The ECT-related mortality rate was calculated as the total number of ECT-related deaths reported in the included studies divided by the total number of ECT treatments...
March 23, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28331498/electroconvulsive-therapy-use-in-youth-in-the-province-of-quebec
#3
Annie Loiseau, Marie-Claude Harrisson, Vincent Beaudry, Simon Patry
OBJECTIVES: Electroconvulsive therapy's (ECT) safety and tolerability is well-established in the treatment of severe psychiatric disorders in adults, but has been less studied in youth. The aim of the present study was to describe the use of ECT in youth in Quebec City and obtain Child and Adolescent Psychiatrists' (CAP) perceptions in the province of Quebec. METHODS: The authors reviewed charts of minors who received ECT treatment in the Quebec City metropolitan area between 1995 and 2014 (part 1)...
2017: Journal of the Canadian Academy of Child and Adolescent Psychiatry
https://www.readbyqxmd.com/read/28322276/identifying-fast-onset-antidepressants-using-rodent-models
#4
M J Ramaker, S C Dulawa
Depression is a leading cause of disability worldwide and a major contributor to the burden of suicide. A major limitation of classical antidepressants is that 2-4 weeks of continuous treatment is required to elicit therapeutic effects, prolonging the period of depression, disability and suicide risk. Therefore, the development of fast-onset antidepressants is crucial. Preclinical identification of fast-onset antidepressants requires animal models that can accurately predict the delay to therapeutic onset. Although several well-validated assay models exist that predict antidepressant potential, few thoroughly tested animal models exist that can detect therapeutic onset...
March 21, 2017: Molecular Psychiatry
https://www.readbyqxmd.com/read/28299981/electroconvulsive-therapy-against-the-patients-will-a-case-series
#5
Isabel Methfessel, Alexander Sartorius, David Zilles
OBJECTIVES: Electroconvulsive therapy (ECT) is the most effective therapy for severe depressive and psychotic disorders. As patients may be subject to legal incapacity and lack of insight, treatment may be administered against the patient's will. There is only limited evidence on the use of ECT against the patient's non-autonomous will. METHODS: We report a series of eight patients who received ECT against their will in two German university medical hospitals between 2014 and 2016...
March 16, 2017: World Journal of Biological Psychiatry
https://www.readbyqxmd.com/read/28297593/clinical-effectiveness-and-cognitive-impact-of-electroconvulsive-therapy-for-schizophrenia-a-large-retrospective-study
#6
Tyler S Kaster, Zafiris J Daskalakis, Daniel M Blumberger
OBJECTIVE: To determine the clinical effectiveness and cognitive impact of electroconvulsive therapy (ECT) in a large clinical sample of patients with schizophrenia and explore factors associated with treatment response and transient cognitive impairment. METHODS: We examined the clinical records of 144 patients with a DSM-IV diagnosis of schizophrenia or schizoaffective disorder who were treated at an academic mental health hospital from October 2009 to August 2014...
March 14, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28295591/acetylcholinesterase-inhibitors-for-electroconvulsive-therapy-induced-cognitive-side-effects-a-systematic-review
#7
REVIEW
Marieke J Henstra, Elise P Jansma, Nathalie van der Velde, Eleonora L Swart, Max L Stek, Didi Rhebergen
OBJECTIVE: Electroconvulsive therapy (ECT) is an effective treatment for severe late-life depression; however, ECT-induced cognitive side effects frequently occur. The cholinergic system is thought to play an important role in the pathogenesis. We systematically reviewed the evidence for acetylcholinesterase inhibitors (Ache-I) to prevent or reduce ECT-induced cognitive side effects. METHODS: A systematic search was performed in Pubmed, EMBASE, PsychINFO, and the Cochrane database to identify clinical trials investigating the effect of Ache-I on ECT-induced cognitive side effects...
March 10, 2017: International Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28292650/frontal-and-temporal-cortical-functional-recovery-after-electroconvulsive-therapy-for-depression-a-longitudinal-functional-near-infrared-spectroscopy-study
#8
Jinichi Hirano, Akihiro Takamiya, Bun Yamagata, Syogo Hotta, Yukiko Miyasaka, Shenghong Pu, Akira Iwanami, Hiroyuki Uchida, Masaru Mimura
While the efficacy and tolerability of electroconvulsive therapy (ECT) for depression has been well established, the acute effects of ECT on brain function remain unclear. Particularly, although cognitive dysfunction has been consistently observed after ECT, little is known about the extent and time course of ECT-induced brain functional changes, as observed during cognitive tasks. Considering the acute antidepressant effects of ECT on depression, aberrant brain functional responses during cognitive tasks in patients with depression may improve immediately after this treatment...
February 22, 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/28288306/challenges-in-comparing-the-acute-cognitive-outcomes-of-high-frequency-repetitive-transcranial-magnetic-stimulation-hf-rtms-vs-electroconvulsive-therapy-ect-in-major-depression-a-systematic-review
#9
Karina Karolina Kedzior, Maria Schuchinsky, Imke Gerkensmeier, Colleen Loo
The present study aimed to systematically compare the cognitive outcomes of high-frequency repetitive transcranial magnetic stimulation (HF-rTMS) and electroconvulsive therapy (ECT) in head-to-head studies with major depression (MDD) patients. A systematic literature search identified six studies with 219 MDD patients that were too heterogeneous to reliably detect meaningful differences in acute cognitive outcomes after ECT vs. HF-rTMS. Cognitive effects of brain stimulation vary depending on the timeframe and methods of assessment, stimulation parameters, and maintenance treatment...
March 2, 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/28277323/individualized-anesthetic-management-for-patients-undergoing-electroconvulsive-therapy-a-review-of-current-practice
#10
Ethan O Bryson, Amy S Aloysi, Kate G Farber, Charles H Kellner
Electroconvulsive therapy (ECT) remains an indispensable treatment for severe psychiatric illness. It is practiced extensively in the United States and around the world, yet there is little guidance for anesthesiologists involved with this common practice. Communication between the anesthesiologist and the proceduralist is particularly important for ECT, because the choice of anesthetic and management of physiologic sequelae of the therapeutic seizure can directly impact both the efficacy and safety of the treatment...
March 8, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28275543/the-global-ect-mri-research-collaboration-gemric-establishing-a-multi-site-investigation-of-the-neural-mechanisms-underlying-response-to-electroconvulsive-therapy
#11
Leif Oltedal, Hauke Bartsch, Ole Johan Evjenth Sørhaug, Ute Kessler, Christopher Abbott, Annemieke Dols, Max L Stek, Lars Ersland, Louise Emsell, Philip van Eijndhoven, Miklos Argyelan, Indira Tendolkar, Pia Nordanskog, Paul Hamilton, Martin Balslev Jorgensen, Iris E Sommer, Sophie M Heringa, Bogdan Draganski, Ronny Redlich, Udo Dannlowski, Harald Kugel, Filip Bouckaert, Pascal Sienaert, Amit Anand, Randall Espinoza, Katherine L Narr, Dominic Holland, Anders M Dale, Ketil J Oedegaard
Major depression, currently the world's primary cause of disability, leads to profound personal suffering and increased risk of suicide. Unfortunately, the success of antidepressant treatment varies amongst individuals and can take weeks to months in those who respond. Electroconvulsive therapy (ECT), generally prescribed for the most severely depressed and when standard treatments fail, produces a more rapid response and remains the most effective intervention for severe depression. Exploring the neurobiological effects of ECT is thus an ideal approach to better understand the mechanisms of successful therapeutic response...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28274337/catatonia-among-women-with-postpartum-psychosis-in-a-mother-baby-inpatient-psychiatry-unit
#12
Abhinav Nahar, Nithin Kondapuram, Geetha Desai, Prabha S Chandra
OBJECTIVE: The aims of the present study were to determine the prevalence of catatonia in women with postpartum psychosis, describe its socio demographic, clinical and obstetric correlates and identify predictors of treatment response. METHODS: Data was extracted from clinical charts of 200 women with postpartum psychosis admitted to an inpatient mother baby unit (MBU) in India over a 3year period. RESULTS: Of the 200 patients, 20% (n=40) had symptoms of catatonia...
March 2017: General Hospital Psychiatry
https://www.readbyqxmd.com/read/28274297/letter-to-the-editor-electrode-placement-in-electroconvulsive-therapy-bilateral-is-still-the-gold-standard-for-some-patients-a-reply
#13
E Kolshus, A Jelovac, D M McLoughlin
No abstract text is available yet for this article.
March 9, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28274287/letter-to-the-editor-electrode-placement-in-electroconvulsive-therapy-bilateral-is-still-the-gold-standard-for-some-patients
#14
C H Kellner, M Cicek, J L Ables
No abstract text is available yet for this article.
March 9, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28272097/electroconvulsive-therapy-at-a-veterans-health-administration-medical-center
#15
Samuel T Wilkinson, Robert A Rosenheck
OBJECTIVES: Little epidemiologic research has examined the practice of electroconvulsive therapy (ECT). We investigated sociodemographic and clinical characteristics, service use, and psychotropic medication prescription patterns associated with ECT use at a Veterans Health Administration Medical Center. METHODS: Among veterans receiving specialty mental health services, we compared those who received ECT with those who did not using bivariate χ and t tests and multivariate logistic regression...
March 8, 2017: Journal of ECT
https://www.readbyqxmd.com/read/28270633/-magnetic-stimulation-therapy-for-mood-disorder
#16
Shinsuke Kito
In Japan, approximately one million patients currently receive medical treatment for mood disorders. However, there are only a few available treatments for patients with treatment-resistant depression or bipolar depression. Repetitive transcranial magnetic stimulation (rTMS), a neuromodulation technique, has proven to be effective for treatment-resistant depression, and also has a potential therapeutic efficacy in patients with bipolar depression who do not respond to medication. Magnetic seizure therapy (MST) is an experimental technique for introducing a seizure by using rTMS, which demonstrates a therapeutic efficacy similar to that of electroconvulsive therapy (ECT), but with fewer cognitive side effects...
March 2017: Brain and Nerve, Shinkei Kenkyū No Shinpo
https://www.readbyqxmd.com/read/28269161/bio-heat-transfer-model-of-electroconvulsive-therapy-effect-of-biological-properties-on-induced-temperature-variation
#17
Marilia M de Oliveira, Paul Wen, Tony Ahfock
A realistic human head model consisting of six tissue layers was modelled to investigate the behavior of temperature profile and magnitude when applying electroconvulsive therapy stimulation and different biological properties. The thermo-electrical model was constructed with the use of bio-heat transfer equation and Laplace equation. Three different electrode montages were analyzed as well as the influence of blood perfusion, metabolic heat and electric and thermal conductivity in the scalp. Also, the effect of including the fat layer was investigated...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28265295/knowledge-of-and-attitudes-towards-electroconvulsive-therapy-ect-among-psychiatrists-and-family-physicians-in-saudi-arabia
#18
Ahmad N AlHadi, Fahad M AlShahrani, Ali A Alshaqrawi, Mohanned A Sharefi, Saud M Almousa
OBJECTIVES: To assess the knowledge of and attitudes towards ECT among psychiatrists and family physicians in Saudi Arabia. METHODS: The study is quantitative observational cross-sectional with a convenient sample that included psychiatrists and family physicians (including residents) in Saudi Arabia. RESULTS: Of the 434 questionnaires emailed, a total of 126 returned completed questionnaires (29% response rate). The mean age of respondents was 35 years old...
2017: Annals of General Psychiatry
https://www.readbyqxmd.com/read/28263242/dexmedetomidine-combined-with-intravenous-anesthetics-in-electroconvulsive-therapy-a-meta-analysis-and-systematic-review
#19
Xiang Li, Fang Tan, Nan Cheng, Na Guo, Zhi-Yong Zhong, Zi-Qing Hei, Qian-Qian Zhu, Shao-Li Zhou
OBJECTIVE: The aim of this study was to investigate how the combined use of dexmedetomidine with intravenous anesthetics influences seizure duration and circulatory dynamics in electroconvulsive therapy (ECT). METHODS: A literature search was performed to identify studies that evaluated the effect of dexmedetomidine on motor- or electroencephalogram (EEG)-based seizure durations and maximum mean arterial pressure (MAP) and heart rate (HR) after ECT. Moreover, recovery time and post-ECT agitation were evaluated...
March 4, 2017: Journal of ECT
https://www.readbyqxmd.com/read/28263241/sylvia-plath-recovered-completely-by-electroconvulsive-therapy-at-the-age-of-21-years-and-might-have-been-saved-by-another-series-9-years-later
#20
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