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https://www.readbyqxmd.com/read/29783976/possible-multiple-system-atrophy-with-predominant-parkinsonism-in-a-patient-with-chronic-schizophrenia-a-case-report
#1
Hiroshi Komatsu, Masaaki Kato, Teiko Kinpara, Takashi Ono, Yoshihisa Kakuto
BACKGROUND: Multiple system atrophy (MSA) is an adult-onset, rare, and progressive neurodegenerative disorder characterized by a varying combination of autonomic failure, cerebellar ataxia, and parkinsonism. MSA is categorized as MSA-P with predominant parkinsonism, and as MSA-C with predominant cerebellar features. The prevalence of MSA has been reported to be between 1.86 and 4.9 cases per 100,000 individuals. In contrast, approximately 1% of the population is affected by schizophrenia during their lifetime; therefore, MSA-P comorbidity is very rare in schizophrenic patients...
May 21, 2018: BMC Psychiatry
https://www.readbyqxmd.com/read/29776678/asystole-a-few-seconds-after-the-electrical-stimulation-of-electroconvulsive-therapy
#2
Shunsuke Takagi, Yuuya Terasawa, Takashi Takeuchi
No abstract text is available yet for this article.
March 23, 2018: Psychosomatics
https://www.readbyqxmd.com/read/29775916/cortisol-trajectory-melancholia-and-response-to-electroconvulsive-therapy
#3
Brian J Mickey, Yarden Ginsburg, Adam F Sitzmann, Clara Grayhack, Srijan Sen, Clemens Kirschbaum, Daniel F Maixner, James L Abelson
While biomarkers have been used to define pathophysiological types and to optimize treatment in many areas of medicine, in psychiatry such biomarkers remain elusive. Based on previously described abnormalities of hypothalamic-pituitary-adrenal (HPA) axis function in severe forms of depression, we hypothesized that the temporal trajectory of basal cortisol levels would vary among individuals with depression due to heterogeneity in pathophysiology, and that cortisol trajectories that reflect elevated or increasing HPA activity would predict better response to electroconvulsive therapy (ECT)...
May 15, 2018: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/29768289/electroconvulsive-therapy-related-anxiety-treat-or-threat
#4
Jasmien Obbels, Esmée Verwijk, Filip Bouckaert, Pascal Sienaert
No abstract text is available yet for this article.
May 15, 2018: Journal of ECT
https://www.readbyqxmd.com/read/29768288/caffeine-sodium-benzoate-for-electroconvulsive-therapy-augmentation
#5
Kevin M Bozymski, Teresa G Potter, Vasu Venkatachalam, Ananda K Pandurangi, Ericka L Crouse
OBJECTIVES: Because of an ongoing manufacturer shortage of injectable caffeine sodium benzoate (CSB), patients at our health system were given CSB compounded in-house to increase seizure response during electroconvulsive therapy (ECT). Therefore, we aimed to evaluate its effectiveness and safety as an ECT augmentation agent. METHODS: Medical records of patients who received compounded CSB at Virginia Commonwealth University Health System were reviewed to identify adults receiving it as part of an index ECT treatment course between June 2012 and December 2016...
May 15, 2018: Journal of ECT
https://www.readbyqxmd.com/read/29765321/brain-lipopolysaccharide-preconditioning-induced-gene-reprogramming-mediates-a-tolerance-state-in-electroconvulsive-shock-model-of-epilepsy
#6
Elham Amini, Mojtaba Golpich, Abdoreza S Farjam, Behnam Kamalidehghan, Zahurin Mohamed, Norlinah M Ibrahim, Abolhassan Ahmadiani, Azman A Raymond
There is increasing evidence pointing toward the role of inflammatory processes in epileptic seizures, and reciprocally, prolonged seizures induce more inflammation in the brain. In this regard, effective strategies to control epilepsy resulting from neuroinflammation could be targeted. Based on the available data, preconditioning (PC) with low dose lipopolysaccharide (LPS) through the regulation of the TLR4 signaling pathway provides neuroprotection against subsequent challenge with injury in the brain. To test this, we examined the effects of a single and chronic brain LPS PC, which is expected to lead to reduction of inflammation against epileptic seizures induced by electroconvulsive shock (ECS)...
2018: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/29758121/the-perspectives-of-former-recipients-and-experts-on-stigmatization-related-to-electroconvulsive-therapy-in-denmark-a-focus-group-study
#7
Iben Sylvia Kring, Maria Daniella Bergholt, Julie Midtgaard
INTRODUCTION: Electroconvulsive therapy (ECT) has existed worldwide for nearly 80 years. Although fast working and potentially life-saving, ECT is regarded as a strongly controversial treatment and stigmatization is frequently mentioned in relation to it. However, no systematic research in this area has taken place so far. AIM: The aim of this qualitative study was to explore the experiences and attitudes of former recipients of ECT and of experts professionally involved with ECT in order to identify potential stigmatization...
May 14, 2018: Journal of Psychiatric and Mental Health Nursing
https://www.readbyqxmd.com/read/29756288/mixed-states-in-bipolar-and-major-depressive-disorders-systematic-review-and-quality-appraisal-of-guidelines
#8
REVIEW
N Verdolini, D Hidalgo-Mazzei, A Murru, I Pacchiarotti, L Samalin, A H Young, E Vieta, A F Carvalho
OBJECTIVE: This systematic review provided a critical synthesis and a comprehensive overview of guidelines on the treatment of mixed states. METHOD: The MEDLINE/PubMed and EMBASE databases were systematically searched from inception to March 21st, 2018. International guidelines covering the treatment of mixed episodes, manic/hypomanic, or depressive episodes with mixed features were considered for inclusion. A methodological quality assessment was conducted with the Appraisal of Guidelines for Research and Evaluation-AGREE II...
May 13, 2018: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/29736058/effects-of-electrical-stimulus-composition-on-cardiac-electrophysiology-in-a-rodent-model-of-electroconvulsive-therapy
#9
Nagendra Madan Singh, T N Sathyaprabha, Jagadisha Thirthalli, Chittaranjan Andrade
Background: No electroconvulsive therapy (ECT) study on humans or in animal models has so far examined whether differently composed electrical stimuli exert different cardiac electrophysiological effects at constant electrical dose. The subject is important because cardiac electrophysiological changes may provide indirect information about ECT seizure quality as modulated by stimulus composition. Materials and Methods: Adult female Wistar rats ( n = 20/group) received fixed, moderately suprathreshold (18 mC) electrical stimuli...
January 2018: Indian Journal of Psychiatry
https://www.readbyqxmd.com/read/29732913/augmentation-strategies-for-clozapine-refractory-schizophrenia-a-systematic-review-and-meta-analysis
#10
Dan J Siskind, Michael Lee, Arul Ravindran, Qichen Zhang, Evelyn Ma, Balaji Motamarri, Steve Kisely
BACKGROUND: Although clozapine is the most effective medication for treatment refractory schizophrenia, only 40% of people will meet response criteria. We therefore undertook a systematic review and meta-analysis of global literature on clozapine augmentation strategies. METHODS: We systematically reviewed PubMed, PsycInfo, Embase, Cochrane Database, Chinese Biomedical Literature Service System and China Knowledge Resource Integrated Database for randomised control trials of augmentation strategies for clozapine resistant schizophrenia...
May 1, 2018: Australian and New Zealand Journal of Psychiatry
https://www.readbyqxmd.com/read/29732911/response-to-rosenman-electroconvulsive-therapy-stimulus-titration-not-all-it-seems
#11
Colleen K Loo, Donel Martin, William Vaughn McCall, Harold Sackeim
No abstract text is available yet for this article.
May 1, 2018: Australian and New Zealand Journal of Psychiatry
https://www.readbyqxmd.com/read/29727307/long-term-cognitive-and-psychological-functioning-in-post-electroconvulsive-therapy-patients
#12
Michelle L Miller, Hien Luu, Owen Gaasedelen, Amanda E Hahn-Ketter, Alexis Elmore, Naseem Dezhkam, John Bayless, David J Moser, Douglas M Whiteside
OBJECTIVE: Electroconvulsive therapy (ECT) is associated with positive outcomes for treatment-resistant mood disorders in the short term. However, there is limited research on long-term cognitive or psychological changes beyond 1 year after -ECT. This study evaluated long-term outcomes in cognitive functioning, psychiatric symptoms, and quality of life for individuals who had undergone ECT. METHODS: Eligible participants (N = 294) who completed a brief pre-ECT neuropsychological assessment within the last 14 years were recruited for a follow-up evaluation; a limited sample agreed to follow-up testing (n = 34)...
May 1, 2018: Journal of ECT
https://www.readbyqxmd.com/read/29720345/-cognitive-side-effects-of-electroconvulsive-therapy
#13
Jeff Zarp Petersen, Kamilla Woznica Miskowiak
Electroconvulsive therapy (ECT) is the most effective treatment for severe depression but is associated with cognitive side effects. Side effects on executive function and memory may persist for months. Patients with a low cognitive reserve and/or poor cognition before ECT seem to be at greater risk of cognitive side effects than patients with a high cognitive reserve. However, better understanding of the nature and predictors of these side effects is needed. We recommend implementing a cognition assessment tool to monitor cognition during ECT...
April 30, 2018: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/29718333/neural-response-after-a-single-ect-session-during-retrieval-of-emotional-self-referent-words-in-depression-a-randomized-sham-controlled-fmri-study
#14
Kamilla W Miskowiak, Julian Macoveanu, Martin B Jørgensen, Mette M Støttrup, Caroline V Ott, Hans M Jensen, Anders Jørgensen, J Harmer, Olaf B Paulson, Lars V Kessing, Hartwig R Siebner
Background: Negative neurocognitive bias is a core feature of depression that is reversed by antidepressant drug treatment. However, it is unclear whether modulation of neurocognitive bias is a common mechanism of distinct biological treatments. This randomized controlled functional magnetic resonance imaging study explored the effects of a single electroconvulsive therapy session on self-referent emotional processing. Methods: Twenty-nine patients with treatment-resistant major depressive disorder were randomized to one active or sham electroconvulsive therapy session at the beginning of their electroconvulsive therapy course in a double-blind, between-groups design...
March 1, 2018: International Journal of Neuropsychopharmacology
https://www.readbyqxmd.com/read/29713175/electroconvulsive-therapy-in-77-year-old-patient-with-pacemaker-a-case-report
#15
Tomasz Mędrala, Anna Pycińska, Bartłomiej Pyciński, Wojciech Merk, Krzysztof Kucia
The treatment of a 77-year-old patient suffering from severe psychotic depression with a cardiac pacemaker is described. Because of treatment-resistant depression, electroconvulsive therapy (ECT) was introduced. In the course of ECT, there was a great improvement in his mental state without any cardiac complications. This case may be evidence for the safety and effectiveness of ECT in the elderly, even with cardiac comorbidities. Some recommendations for ECT in patients with pacemakers are discussed.
2018: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/29707778/electroconvulsive-therapy-increases-brain-volume-in-major-depression-a-systematic-review-and-meta-analysis
#16
REVIEW
K Gbyl, P Videbech
OBJECTIVE: The main purpose of this review was to synthesise evidence on ECT's effects on brain's structure. METHOD: A systematic literature review of longitudinal studies of depressed patients treated with ECT using magnetic resonance imaging (MRI) and meta-analysis of ECT's effect on hippocampal volume. RESULTS: Thirty-two studies with 467 patients and 285 controls were included. The MRI studies did not find any evidence of ECT-related brain damage...
April 29, 2018: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/29707426/is-electroconvulsive-therapy-a-treatment-for-depression-following-traumatic-brain-injury
#17
Anja Srienc, Puneet Narang, Simrat Sarai, Yee Xiong, Steven Lippmann
Traumatic brain injury (TBI) can be caused by blunt or penetrating injury to the head. The pathophysiological evolution of TBI involves complex biochemical and genetic changes. Common sequelae of TBI include seizures and psychiatric disorders, particularly depression. In considering pharmacologic interventions for treating post-TBI depression, it is important to remember that TBI patients have a higher risk of seizures; therefore, the benefits of prescribing medications that lower the seizure threshold need to be weighed against the risk of seizures...
April 1, 2018: Innovations in Clinical Neuroscience
https://www.readbyqxmd.com/read/29703415/electroconvulsive-therapy-for-depression-in-a-patient-with-an-inspire-hypoglossal-nerve-stimulator-device-for-obstructive-sleep-apnea-a-case-report
#18
Katie Mingo, Alan Kominsky
OUTCOME OBJECTIVES: METHODS: This is a case report of a patient who underwent placement and initiation of a hypoglossal nerve stimulator device in the context of receiving electroconvulsive therapy for bipolar depression between February and September 2016. To our knowledge, this has not yet been reported in the literature. Outcome measurements included successful device activation and successful device use throughout electroconvulsive therapy. RESULTS: The patient underwent successful device implantation, activation, and use without disruption throughout electroconvulsive therapy sessions...
April 19, 2018: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/29700801/ketamine-based-anesthesia-improves-electroconvulsive-therapy-outcomes-a-randomized-controlled-study
#19
Jonathan J Gamble, Henry Bi, Rudy Bowen, Grahme Weisgerber, Rohan Sanjanwala, Renuka Prasad, Lloyd Balbuena
BACKGROUND: Major depressive disorder (MDD) is a common and debilitating condition that can be challenging to treat. Electroconvulsive therapy (ECT) is currently the therapeutic gold standard for treatment-resistant MDD. We tested our hypothesis that ketamine-based anesthesia for ECT results in superior improvement in treatment-resistant MDD outcomes compared with propofol-based anesthesia. METHODS: Patients with treatment-resistant MDD were enrolled in a randomized clinical trial with assignment to ketamine- or propofol-based anesthesia arms...
February 21, 2018: Canadian Journal of Anaesthesia, Journal Canadien D'anesthésie
https://www.readbyqxmd.com/read/29697715/catatonia-in-the-medically-ill-etiology-diagnosis-and-treatment-the-academy-of-consultation-liaison-psychiatry-evidence-based-medicine-subcommittee-monograph
#20
Lex Denysenko, Nicole Sica, Thomas M Penders, Kemuel L Philbrick, Audrey Walker, Scott Shaffer, Paula Zimbrean, Oliver Freudenreich, Nicole Rex, Brendan T Carroll, Andrew Francis
BACKGROUND: Catatonia in medically ill patients is rare but often unrecognized. This monograph summarizes current knowledge on the diagnosis, epidemiology, etiology, and management of catatonia occurring in the medical setting. METHODS: PubMed searches were used to identify relevant articles from 1962 to present. RESULTS: More than 3,000 articles were obtained and reviewed for relevance, including references of articles identified by the initial search...
May 2018: Annals of Clinical Psychiatry: Official Journal of the American Academy of Clinical Psychiatrists
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