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https://www.readbyqxmd.com/read/27904627/antimicrobial-effects-of-chlorhexidine-matrica-drop-mouthwash-chamomile-extract-and-normal-saline-on-hospitalized-patients-with-endotracheal-tubes
#1
Maryam Azimi, Leila Jouybari, Shahram Moghadam, Ezatolah Ghaemi, Naser Behnampoor, Akram Sanagoo, Moslem Hesam
BACKGROUND: The functions and use of mouthwashes are variable depending on their type. Oral care in patients with endotracheal tubes is important to prevent side effects such as pneumonia. The aim of this study was to determine the antimicrobial effects of chlorhexidine, drop of Matrica mouthwash (chamomile extract), and normal saline on hospitalized patients with endotracheal tube in an intensive care unit (ICU). MATERIALS AND METHODS: In this clinical trial, 39 patients admitted to the ICU were selected by convenience sampling, were matched based on age and sex, and randomly assigned to three groups (chlorhexidine, Matrica, saline)...
September 2016: Iranian Journal of Nursing and Midwifery Research
https://www.readbyqxmd.com/read/27885559/erratum-to-synergistic-effect-of-programmed-cell-death-protein-1-blockade-and-secondary-lymphoid-tissue-chemokine-in-the-induction-of-anti-tumor-immunity-by-a-therapeutic-cancer-vaccine
#2
Soheila Moeini, Mohsen Saeidi, Fatemeh Fotouhi, Mahdieh Mondanizadeh, Sadegh Shirian, Alireza Mohebi, Ali Gorji, Amir Ghaemi
No abstract text is available yet for this article.
November 24, 2016: Archives of Virology
https://www.readbyqxmd.com/read/27858348/bipolar-disorder-in-the-digital-age-new-tools-for-the-same-illness
#3
John Torous, Paul Summergrad, S Nassir Ghaemi
"Nothing is more difficult than to ascertain the length of time that a maniacal patient can exist without sleep."-Dr. Sutherland (Br J Psychiatry 7(37):1-19, 1861). Dr. Sutherland's patient was suffering from an acute manic episode, which today is called bipolar illness. 150 years later, we continue to struggle with the same challenges in ascertaining accurate symptoms from patients. In era of new digital tools, the quantified self-movement, and precision medicine, we can ask the question: Can we advance understanding and treatment for bipolar illness beyond asking the same questions as in 1861?...
December 2016: International Journal of Bipolar Disorders
https://www.readbyqxmd.com/read/27854079/synthesis-of-different-layers-of-graphene-on-stainless-steel-using-the-cvd-method
#4
Ferial Ghaemi, Luqman Chuah Abdullah, Paridah Md Tahir, Robiah Yunus
In this study, different types of graphene, including single-, few-, and multi-layer graphene, were grown on a stainless steel (SS) mesh coated with Cu catalyst by using the chemical vapor deposition (CVD) method. Even though the SS mesh consisted of different types of metals, such as Fe, Ni, and Cr, which can also be used as catalysts, the reason for coating Cu catalyst on the SS surface had been related to the nature of the Cu, which promotes the growth of graphene with high quality and quantity at low temperature and time...
December 2016: Nanoscale Research Letters
https://www.readbyqxmd.com/read/27826323/bipolar-i-and-ii-disorders-a-systematic-review-and-meta-analysis-on-differences-in-comorbid-obsessive-compulsive-disorder
#5
REVIEW
Andrea Amerio, Brendon Stubbs, Anna Odone, Matteo Tonna, Carlo Marchesi, S Nassir Ghaemi
CONTEXT: More than half of the bipolar disorder (BD) cases have an additional diagnosis; one of the most difficult to manage is obsessive-compulsive disorder (OCD). Although some authors recently investigated the co-occurrence of anxiety and BD, the topic remains insufficiently studied. The current study aimed to investigate differences in comorbid OCD between BD-I and BD-II. EVIDENCE ACQUISITION: A systematic review and meta-analysis was conducted on the prevalence and predictors of comorbid BD-I/BD-II and OCD...
September 2016: Iranian Journal of Psychiatry and Behavioral Sciences
https://www.readbyqxmd.com/read/27807992/radiation-induced-surge-of-macrophage-foam-cell-formation-oxidative-damage-and-cytokine-release-is-attenuated-by-a-nanoformulation-of-curcumin
#6
Behrooz Soltani, Narges Bodaghabadi, Nasser Ghaemi, Majid Sadeghizadeh
PURPOSE: We examined the potential of a dendrosomal nanoformulation of curcumin (DNC) for intervention of ionizing radiation (IR)-induced damage (particularly leading to atherosclerosis), employing an irradiated THP-1 macrophage model. MATERIALS AND METHODS: Differentiated THP-1 macrophages were irradiated and treated with curcumin or DNC nanoformulation (and oxidized low density lipoprotein, ox-LDL, to promote foam cells). Chemical, biochemical, and genetics tools including viability and apoptosis, multiple ELISA, real-time PCR, Western blotting, enzyme activity, and fluorimetry assays were employed to illustrate IR damage as well as the DNC intervention potential...
November 3, 2016: International Journal of Radiation Biology
https://www.readbyqxmd.com/read/27800133/staphylococcal-cassette-chromosome-mec-types-among-methicillin-resistant-staphylococcus-aureus-in-northern-iran
#7
Akram Taherirad, Roghayeh Jahanbakhsh, Fatemeh Shakeri, Shaghayegh Anvary, Ezzat Allah Ghaemi
BACKGROUND: Methicillin-resistant Staphylococcus aureus (MRSA) is a common cause of nosocomial and community-acquired infections around the world. Staphylococcal cassette chromosome mec (SCCmec) typing methods are often used to study MRSA molecular epidemiology. OBJECTIVES: The current study was designed to explore the distribution profiles of different SCCmec types among methicillin-resistant S. aureus strains isolated from hospitals in Gorgan, in northern Iran, and to correlate the types into observed bacterial virulence factors...
August 2016: Jundishapur Journal of Microbiology
https://www.readbyqxmd.com/read/27790337/a-hospital-base-epidemiology-and-pattern-of-acute-adult-poisoning-across-iran-a-systematic-review
#8
REVIEW
Malihe Moradi, Kazem Ghaemi, Omid Mehrpour
INTRODUCTION: Poisoning is one of the most important health issues in the world. There is no exact statistic regarding the epidemiology of poisoning in Iran. The aim of this systematic review was to study the epidemiology of poisoning of adults in Iran. METHODS: All the published papers regarding the epidemiology and patterns of adult poisonings in different parts of Iran were reviewed in bibliographical databases, including SID, Iran Medex, Medlib, Magiran and Embase, Scopus, PubMed, and Google Scholar, without time limitation up to March 21, 2016...
September 2016: Electronic Physician
https://www.readbyqxmd.com/read/27721961/prevalence-of-non-alcoholic-fatty-liver-disease-and-its-related-factors-in-iran
#9
I Moghaddasifar, K B Lankarani, M Moosazadeh, M Afshari, A Ghaemi, M Aliramezany, R Afsar Gharebagh, M Malary
BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is the most prevalent chronic liver disease in developing and developed countries. Estimating the total prevalence of NAFLD by means of appropriate statistical methods can provide reliable evidence for health policy makers. OBJECTIVE: To determine the prevalence of NAFLD in Iran using a systematic review and meta-analysis. METHODS: We identified relevant studies by searching national and international databases...
2016: International Journal of Organ Transplantation Medicine
https://www.readbyqxmd.com/read/27699512/synergistic-effect-of-programmed-cell-death-protein%C3%A2-1-blockade-and-secondary-lymphoid-tissue-chemokine-in-the-induction-of-anti-tumor-immunity-by-a-therapeutic-cancer-vaccine
#10
Soheila Moeini, Mohsen Saeidi, Fatemeh Fotouhi, Mahdieh Mondanizadeh, Sadegh Shirian, Alireza Mohebi, Ali Gorji, Amir Ghaemi
The use of DNA vaccines has become an attractive approach for generating antigen-specific cytotoxic CD8(+) T lymphocytes (CTLs), which can mediate protective antitumor immunity. The potency of DNA vaccines encoding weakly immunogenic tumor-associated antigens (TAAs) can be improved by using an adjuvant injected together with checkpoint antibodies. In the current study, we evaluated whether the therapeutic effects of a DNA vaccine encoding human papilloma virus type 16 (HPV-16) E7 can be enhanced by combined application of an immune checkpoint blockade directed against the programmed death-1 (PD-1) pathway and secondary lymphoid tissue chemokine (SLC) also known as CCL21 adjuvant, in a mouse cervical cancer model...
October 3, 2016: Archives of Virology
https://www.readbyqxmd.com/read/27693263/psychosexual-outcome-among-iranian-individuals-with-5%C3%AE-reductase-deficiency-type-2-and-its-relationship-with-parental-sexism
#11
Behzad S Khorashad, Zahra Aghili, Baudewijntje P C Kreukels, Mehran Hiradfar, Ghasem M Roshan, Mozhgan Afkhamizadeh, Mohammad Reza Abbaszadegan, Nosrat Ghaemi, Behnaz Khazai, P T Cohen-Kettenis
INTRODUCTION: Few studies exist on the psychosexual outcome of homogeneous groups of individuals with 5α-reductase deficiency type 2 (5α-RD-2) and the relation between gender changes and parental hostile and benevolent sexism, which are two components of ambivalent sexism that assume a stereotypical approach toward women in an overtly negative way or a chivalrous, seemingly positive way. AIM: To report on the psychosexual outcome of individuals with 5α-RD-2 and to investigate its relation to the level of parental sexism in a relatively large sample of Iranians with 5α-RD-2...
November 2016: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/27622345/antimicrobial-resistance-of-listeria-monocytogenes-isolated-from-seafood-and-humans-in-iran
#12
Esmail Abdollahzadeh, Seyed Mahdi Ojagh, Hedayat Hosseini, Ezzat Allah Ghaemi, Gholamreza Irajian, Masoud Naghizadeh Heidarlo
Fourteen Listeria monocytogenes isolates previously collected from seafood (n = 7) and human patients (n = 7) were studied for their antimicrobial susceptibility against eight common antimicrobials (ampicillin, penicillin, gentamicin, streptomycin, tetracycline, trimethoprim-sulfamethoxazole, chloramphenicol, and cefotaxime). A high resistance level to ampicillin, cefotaxime (100%), and pencillin (57% in seafood isolates and 71.4% in clinical isolates) was observed in this study. However, all of the isolates were susceptible to trimethoprim-sulfamethoxazole, chloramphenicol, and tetracycline...
September 10, 2016: Microbial Pathogenesis
https://www.readbyqxmd.com/read/27611723/the-international-mood-network-imn-nosology-project-differentiating-borderline-personality-from-bipolar-illness
#13
P A Vöhringer, S A Barroilhet, K Alvear, S Medina, C Espinosa, K Alexandrovich, P Riumallo, F Leiva, M E Hurtado, J Cabrera, M Sullivan, N Holtzman, S N Ghaemi
OBJECTIVE: The differential diagnosis of bipolar illness vs. borderline personality is controversial. Both conditions manifest impulsive behavior, unstable interpersonal relationships, and mood symptoms. This study examines whether and which mood clinical features can differentiate between both conditions. METHOD: A total of 260 patients (mean ± standard deviation age 41 ± 13 years, 68% female) attending to a mood clinic were examined for diagnosis of bipolar illness and borderline personality disorder using SCID-I, SCID-II, and clinical mood criteria extracted from Mood Disorder Questionnaire (MDQ)...
December 2016: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/27600088/a-combinatorial-protein-microarray-for-probing-materials-interaction-with-pancreatic-islet-cell-populations
#14
Bahman Delalat, Darling M Rojas-Canales, Soraya Rasi Ghaemi, Michaela Waibel, Frances J Harding, Daniella Penko, Christopher J Drogemuller, Thomas Loudovaris, Patrick T H Coates, Nicolas H Voelcker
Pancreatic islet transplantation has become a recognized therapy for insulin-dependent diabetes mellitus. During isolation from pancreatic tissue, the islet microenvironment is disrupted. The extracellular matrix (ECM) within this space not only provides structural support, but also actively signals to regulate islet survival and function. In addition, the ECM is responsible for growth factor presentation and sequestration. By designing biomaterials that recapture elements of the native islet environment, losses in islet function and number can potentially be reduced...
August 10, 2016: Microarrays
https://www.readbyqxmd.com/read/27578405/magnetized-graphene-layers-synthesized-on-the-carbon-nanofibers-as-novel-adsorbent-for-the-extraction-of-polycyclic-aromatic-hydrocarbons-from-environmental-water-samples
#15
Mostafa Rezvani-Eivari, Amirhassan Amiri, Mehdi Baghayeri, Ferial Ghaemi
The application of magnetized graphene (G) layers synthesized on the carbon nanofibers (CNFs) (m-G/CNF) was investigated as novel adsorbent for the magnetic solid-phase extraction (MSPE) of polycyclic aromatic hydrocarbons (PAHs) in water samples followed by gas chromatography-flame ionization detector (GC-FID). Six important parameters, affecting the extraction efficiency of PAHs, including: amount of adsorbent, adsorption and desorption times, type and volume of the eluent solvent and salt content of the sample were evaluated...
September 23, 2016: Journal of Chromatography. A
https://www.readbyqxmd.com/read/27558390/nanoformulation-of-curcumin-protects-huvec-endothelial-cells-against-ionizing-radiation-and-suppresses-their-adhesion-to-monocytes-potential-in-prevention-of-radiation-induced-atherosclerosis
#16
Behrooz Soltani, Narges Bodaghabadi, Gita Mahpour, Nasser Ghaemi, Majid Sadeghizadeh
OBJECTIVES: To investigated the potential of a novel dendrosomal nanoformulation of curcumin (DNC) in blocking radiation-induced changes in irradiated human umbilical vein endothelial cells (HUVECs), and their adhesion to human THP-1 monocytoid cells. RESULTS: Co(60) gamma rays reduced viability, raised the expression of adhesion molecules, ICAM-1, VCAM-1 and E-selectin (mRNA and protein), augmented the adhesion of THP-1 cells to HUVECs, activated NF-κB binding, increased the release of pro-inflammatory cytokines (IL-6, IL-8 and MCP-1) and induced oxidative damage (reduced glutathione declined, while 8-OHdG and TBARS increased)...
August 24, 2016: Biotechnology Letters
https://www.readbyqxmd.com/read/27529183/estimation-of-relative-protein-rna-binding-strengths-from-fluctuations-in-the-bound-state
#17
Zhaleh Ghaemi, Irisbel Guzman, Jung-Un Julia Baek, Martin Gruebele, Zaida Luthey-Schulten
Protein-RNA complexes are increasingly important in our understanding of cell signaling, metabolism, and transcription. Electrostatic interactions play dominant role in stabilizing such complexes. Using conventional computational approaches, very long simulations of both bound and unbound states are required to obtain accurate estimates of complex dissociation constants (Kd). Here, we derive a simple formula that offers an alternative approach based on the theory of fluctuations. Our method extracts a strong correlate to experimental Kd values using short molecular dynamics simulations of the bound complex only...
September 13, 2016: Journal of Chemical Theory and Computation
https://www.readbyqxmd.com/read/27500169/acceptance-and-satisfaction-of-parents-and-students-about-a-school-based-dietary-intervention-in-isfahan-2012-2013
#18
Roya Kelishadi, Bahareh Lajevardi, Maryam Bahreynian, Vahid Omid-Ghaemi, Mahsa Movahedian
OBJECTIVE: Snacks play an important role in child health and nutritional status. Schools are considered as the preferred place to encourage healthy eating among children. The aim of this study was to evaluate the effect of buffet school-based intervention on acceptance and satisfaction of parents and students in Iran. MATERIALS AND METHODS: Primary school students (n = 1120, 68.83% girls) from first to third grade, with one of their parents, participated in this prospective field trial study conducted in Isfahan, Iran...
2016: Journal of Education and Health Promotion
https://www.readbyqxmd.com/read/27489591/evaluation-of-bone-mineral-density-in-children-with-acute-lymphoblastic-leukemia-all-and-non-hodgkin-s-lymphoma-nhl-chemotherapy-with-without-radiotherapy
#19
Ali Ghassemi, Abdollah Banihashem, Nosrate Ghaemi, Saghi Elmi, Reza Erfani Sayyar, Sam Elmi, Habibollah Esmaeili
BACKGROUND: Acute lymphoblastic leukemia (ALL) and non-Hodgkin's lymphoma (NHL) are the most common malignancies in children and adolescents. Therapies such as corticosteroids, cytotoxic and radiotherapy will have harmful effect on bone mineral density (BMD) which can lead to increased possibility of osteoporosis and pathological fractures. SUBJECTS AND METHODS: This 3-year cross-sectional study was performed in 50 children with ALL (n=25) and NHL (n=25) at Dr. Sheikh Children's Hospital in Mashhad...
July 1, 2016: International Journal of Hematology-oncology and Stem Cell Research
https://www.readbyqxmd.com/read/27473378/curcumin-confers-protection-to-irradiated-thp-1-cells-while-its-nanoformulation-sensitizes-these-cells-via-apoptosis-induction
#20
Behrooz Soltani, Nasser Ghaemi, Majid Sadeghizadeh, Farhood Najafi
Protection against ionizing radiation (IR) and sensitization of cancer cells to IR are apparently contrasting phenomena. However, curcumin takes on these contrasting roles leading to either protection or enhanced apoptosis in different irradiated cells. Here we studied whether pretreatment with free curcumin or a novel dendrosomal nanoformulation of curcumin (DNC) could exert protective/sensitizing effects on irradiated THP-1 leukemia cells. We employed assays including MTT viability, clonogenic survival, DNA fragmentation, PI/Annexin V flow cytometry, antioxidant system (ROS, TBARS for lipid peroxidation, 8-OHdG and γH2AX for DNA damage, glutathione, CAT and GPx activity, enzymes gene expression), ELISA (NF-κB and Nrf2 binding, TNF-α release), caspase assay, siRNA silencing of caspase-3, and western blotting to illustrate the observed protective role of curcumin in comparison with the opposite sensitizing role of its nanoformulation at a similar 10 μM concentration...
July 29, 2016: Cell Biology and Toxicology
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