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https://www.readbyqxmd.com/read/29134548/a-didactic-course-on-philosophy-of-psychiatry-for-psychiatry-residents
#1
Awais Aftab, S Nassir Ghaemi, Susan Stagno
No abstract text is available yet for this article.
November 13, 2017: Academic Psychiatry
https://www.readbyqxmd.com/read/29126466/graphene-grown-on-stainless-steel-mesh-as-a-highly-efficient-sorbent-for-sorptive-microextraction-of-polycyclic-aromatic-hydrocarbons-from-water-samples
#2
Amirhassan Amiri, Ferial Ghaemi
In this study, graphene grown on stainless steel mesh efficiently incorporates the advanced properties of graphene in the form of an ultra-thin coating with the open geometry of the substrate, resulting in a highly sensitive and fast sorptive device capable of extracting target analytes directly from sample matrices. The synthesis of graphene on the stainless steel mesh was confirmed by scanning electron microscopy (SEM) and transmission electron microscopy (TEM). The advantages of the new microextraction device have been investigated for the determination of polycyclic aromatic hydrocarbons (PAHs) in environmental water samples in combination with gas chromatography-flame ionization detector (GC-FID)...
November 22, 2017: Analytica Chimica Acta
https://www.readbyqxmd.com/read/29098171/the-mars-science-laboratory-msl-mast-cameras-and-descent-imager-investigation-and-instrument-descriptions
#3
Michal C Malin, Michael A Ravine, Michael A Caplinger, F Tony Ghaemi, Jacob A Schaffner, Justin N Maki, James F Bell, James F Cameron, William E Dietrich, Kenneth S Edgett, Laurence J Edwards, James B Garvin, Bernard Hallet, Kenneth E Herkenhoff, Ezat Heydari, Linda C Kah, Mark T Lemmon, Michelle E Minitti, Timothy S Olson, Timothy J Parker, Scott K Rowland, Juergen Schieber, Ron Sletten, Robert J Sullivan, Dawn Y Sumner, R Aileen Yingst, Brian M Duston, Sean McNair, Elsa H Jensen
The Mars Science Laboratory Mast camera and Descent Imager investigations were designed, built, and operated by Malin Space Science Systems of San Diego, CA. They share common electronics and focal plane designs but have different optics. There are two Mastcams of dissimilar focal length. The Mastcam-34 has an f/8, 34 mm focal length lens, and the M-100 an f/10, 100 mm focal length lens. The M-34 field of view is about 20° × 15° with an instantaneous field of view (IFOV) of 218 μrad; the M-100 field of view (FOV) is 6...
August 2017: Earth and Space Science (Hoboken, N.J.)
https://www.readbyqxmd.com/read/29082033/maintenance-efficacy-designs-in-psychiatry-randomized-discontinuation-trials-enriched-but-not-better
#4
REVIEW
S N Ghaemi, Harry P Selker
INTRODUCTION: Although classical randomized clinical trials (RCTs) are the gold standard for proof of drug efficacy, randomized discontinuation trials (RDTs), sometimes called "enriched" trials, are used increasingly, especially in psychiatric maintenance studies. METHODS: A narrative review of two decades of experience with RDTs. RESULTS: RDTs in psychiatric maintenance trials tend to use a dependent variable as a predictor: treatment response...
June 2017: Journal of clinical and translational science
https://www.readbyqxmd.com/read/29072182/social-challenges-of-contemporary-psychiatry
#5
N Bouras
Psychiatry and society are interrelated and the biopsychosocial model continues to dominate the clinical psychiatric practice. Some doubts have been expressed in recent years about the value and the wide acceptance of the biopsychosocial model. Ghaemi (2009)1 considers it to be anti-humanistic and advocates the use of less eclectic, less generic, and less vague alternatives. The fundamental changes that have been witnessed in our times across the spectrum of biology, psychology and sociology have made necessary that a conceptual clarity should prevail...
July 2017: Psychiatrikē, Psychiatriki
https://www.readbyqxmd.com/read/29058002/a-microfluidic-microinjector-for-toxicological-and-developmental-studies-in-drosophila-embryos
#6
Reza Ghaemi, Pouya Arefi, Ana Stosic, Meryl Acker, Qanber Raza, J Roger Jacobs, Ponnambalam Ravi Selvaganapathy
Microinjection is an established and reliable method to deliver biological reagents such as transgenic constructs and drugs, to specific locations inside organisms such as the Drosophila embryo and C. elegans worm. In this paper, a simple compliant mechanism based PDMS-microinjection system has been demonstrated. Unlike conventional microinjectors, this unique system could allow one to precisely insert a long taper microneedle laterally and at various positions inside the length of the Drosophila embryo (up to 250 μm) with the resolution of 5 μm...
November 7, 2017: Lab on a Chip
https://www.readbyqxmd.com/read/29045140/the-conformational-change-in-elongation-factor-tu-involves-separation-of-its-domains
#7
Jonathan Lai, Zhaleh Ghaemi, Zaida Luthey-Schulten
Elongation factor Tu (EF-Tu) is a highly conserved GTPase that is responsible for supplying the aminoacylated tRNA to the ribosome. Upon binding to the ribosome, EF-Tu undergoes GTP hydrolysis, which drives a major conformational change, triggering the release of aminoacylated tRNA to the ribosome. Using a combination of molecular simulation techniques, we studied the transition between the pre- and post-hydrolysis structures through two distinct pathways. We show that the transition free energy is minimal along a non-intuitive pathway that involves "separation" of the GTP binding domain (domain 1) from the OB folds (domains 2 and 3), followed by domain 1 rotation, and, eventually, locking the EF-Tu conformation in the post-hydrolysis state...
October 27, 2017: Biochemistry
https://www.readbyqxmd.com/read/29044139/diabetes-in-iran-prospective-analysis-from-first-nationwide-diabetes-report-of-national-program-for-prevention-and-control-of-diabetes-nppcd-2016
#8
Alireza Esteghamati, Bagher Larijani, Mohammad Haji Aghajani, Fatemeh Ghaemi, Jamshid Kermanchi, Ali Shahrami, Mohammad Saadat, Ensieh Nasli Esfahani, Morsaleh Ganji, Sina Noshad, Elias Khajeh, Alireza Ghajar, Behnam Heidari, Mohsen Afarideh, Jeffrey I Mechanick, Faramarz Ismail-Beigi
We estimated proportions of different types of diabetes, comorbidities, treatment (the use of oral glucose-lowering agents and insulin), control (hyperglycemia, dyslipidemia and hypertension) and chronic microvascular and macrovascular complications among people with diabetes presenting to the tertiary-care academic diabetes outpatient clinics in Iran. This study is the prospective analysis of data (n = 30,202) from the registry of university-affiliated adult outpatient diabetes clinics in the country during 2015-2016...
October 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28987245/the-effect-of-relaxation-on-mother-s-anxiety-and-maternal-fetal-attachment-in-primiparous-ivf-mothers
#9
Monireh Toosi, Marzieh Akbarzadeh, Zahra Ghaemi
OBJECTIVES: Infertility is one of the main stressful events of life and a crisis affecting various dimensions of infertile couples' lives. Relaxation, as a strategy, can be effective in the individuals' resistance to stress and anxiety. Therefore, the present study aimed to assess the effect of relaxation on mother's anxiety and maternal-fetal attachment in primiparous women who used In Vitro Fertilization (IVF) to get pregnant. METHODS: In this clinical trial, 80 primiparous women who had used IVF to get pregnant were randomly divided into a control and an intervention group...
2017: Journal of the National Medical Association
https://www.readbyqxmd.com/read/28967391/indirect-predictive-type-2-fuzzy-neural-network-controller-for-a-class-of-nonlinear-input-delay-systems
#10
Kamel Sabahi, Sehraneh Ghaemi, Jianxing Liu, Mohammad Ali Badamchizadeh
In this paper a new indirect type-2 fuzzy neural network predictive (T2FNNP) controller has been proposed for a class of nonlinear systems with input-delay in presence of unknown disturbance and uncertainties. In this method, the predictor has been utilized to estimate the future state variables of the controlled system to compensate for the time-varying delay. The T2FNN is used to estimate some unknown nonlinear functions to construct the controller. By introducing a new adaptive compensator for the predictor and controller, the effects of the external disturbance, estimation errors of the unknown nonlinear functions, and future sate estimation errors have been eliminated...
September 26, 2017: ISA Transactions
https://www.readbyqxmd.com/read/28914948/nanotopography-mediated-osteogenic-differentiation-of-human-dental-pulp-derived-stem-cells
#11
Akash Bachhuka, Bahman Delalat, Soraya Rasi Ghaemi, Stan Gronthos, Nicolas H Voelcker, Krasimir Vasilev
Advanced medical devices, treatments and therapies demand an understanding of the role of interfacial properties on the cellular response. This is particularly important in the emerging fields of cell therapies and tissue regeneration. In this study, we evaluate the role of surface nanotopography on the fate of human dental pulp derived stem cells (hDPSC). These stem cells have attracted interest because of their capacity to differentiate to a range of useful lineages but are relatively easy to isolate. We generated and utilized density gradients of gold nanoparticles which allowed us to examine, on a single substrate, the influence of nanofeature density and size on stem cell behavior...
September 28, 2017: Nanoscale
https://www.readbyqxmd.com/read/28894784/blood-lead-levels-in-asymptomatic-opium-addict-patients-a-case-control-study
#12
Kazem Ghaemi, Atefeh Ghoreishi, Navid Rabiee, Samira Alinejad, Esmaeil Farzaneh, Alireza Amirabadi Zadeh, Mohammad Abdollahi, Omid Mehrpour
INTRODUCTION: One of the newest non-occupational sources of lead contamination is drug addiction, which has recently been addressed as a major source of lead poisoning in some countries. The present study aimed to investigate the blood lead level (BLL) of asymptomatic opium addicts. METHODS: This case-control study was conducted during a one-year period to compare BLL of three groups consisting of opium addicts, patients under methadone maintenance therapy (MMT), and healthy individuals...
2017: Emergency (Tehran, Iran)
https://www.readbyqxmd.com/read/28883878/the-report-of-three-rare-cases-of-the-niemann-pick-disease-in-birjand-south-khorasan-eastern-iran
#13
Samaneh Noroozi Asl, Rahim Vakili, Nosrat Ghaemi, Peyman Eshraghi
Niemann-Pick disease type C (NP-C) is a rare neurovisceral and irreversible disease leading to premature death and disabling neurological signs. This autosomal recessive disease with incidence rate of 1:120000 is caused by mutations in either the NPC1 or the NPC2 gene, which leads to accumulation of cholesterol in body tissues especially brain and progressive neurological symptoms. NP-C is characterized by nonspecific visceral, neurological and psychiatric manifestations in infants. The neurological involvement is typically proceeded by systemic signs (cholestatic jaundice in the neonatal period or isolated spleno-or hepatosplenomegaly in infancy or childhood)...
2017: Iranian Journal of Child Neurology
https://www.readbyqxmd.com/read/28864494/an-immune-clock-of-human-pregnancy
#14
Nima Aghaeepour, Edward A Ganio, David Mcilwain, Amy S Tsai, Martha Tingle, Sofie Van Gassen, Dyani K Gaudilliere, Quentin Baca, Leslie McNeil, Robin Okada, Mohammad S Ghaemi, David Furman, Ronald J Wong, Virginia D Winn, Maurice L Druzin, Yaser Y El-Sayed, Cecele Quaintance, Ronald Gibbs, Gary L Darmstadt, Gary M Shaw, David K Stevenson, Robert Tibshirani, Garry P Nolan, David B Lewis, Martin S Angst, Brice Gaudilliere
The maintenance of pregnancy relies on finely tuned immune adaptations. We demonstrate that these adaptations are precisely timed, reflecting an immune clock of pregnancy in women delivering at term. Using mass cytometry, the abundance and functional responses of all major immune cell subsets were quantified in serial blood samples collected throughout pregnancy. Cell signaling-based Elastic Net, a regularized regression method adapted from the elastic net algorithm, was developed to infer and prospectively validate a predictive model of interrelated immune events that accurately captures the chronology of pregnancy...
September 1, 2017: Science Immunology
https://www.readbyqxmd.com/read/28806086/role-of-electrostatics-in-protein-rna-binding-the-global-vs-the-local-energy-landscape
#15
Zhaleh Ghaemi, Irisbel Guzman, David Gnutt, Zaida Luthey-Schulten, Martin Gruebele
U1A protein-stem loop 2 RNA association is a basic step in the assembly of the spliceosomal U1 small nuclear ribonucleoprotein. Long-range electrostatic interactions due to the positive charge of U1A are thought to provide high binding affinity for the negatively charged RNA. Short range interactions, such as hydrogen bonds and contacts between RNA bases and protein side chains, favor a specific binding site. Here, we propose that electrostatic interactions are as important as local contacts in biasing the protein-RNA energy landscape toward a specific binding site...
August 31, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28804616/zinc-oxide-nanoparticle-reduced-biofilm-formation-and-antigen-43-expressions-in-uropathogenic-escherichiacoli
#16
Ali Shakerimoghaddam, Ezzat A Ghaemi, Ailar Jamalli
OBJECTIVES: This study aimed to investigate the effect of zinc oxide nanoparticles (ZnO-np) on biofilm formation and expression of the flu gene in uropathogenic Escherichia coli (UPEC) strains. MATERIALS AND METHODS: Minimum inhibitory concentration (MIC) of ZnO-np was determined by agar dilution method. The effect of MIC and sub-MIC concentrations of ZnO-np on biofilm formation were determined by microtiter plate assay. The expression level of the flu gene was assessed by Real-Time PCR assay...
April 2017: Iranian Journal of Basic Medical Sciences
https://www.readbyqxmd.com/read/28761338/a-review-of-fibrin-and-fibrin-composites-for-bone-tissue-engineering
#17
REVIEW
Alireza Noori, Seyed Jamal Ashrafi, Roza Vaez-Ghaemi, Ashraf Hatamian-Zaremi, Thomas J Webster
Tissue engineering has emerged as a new treatment approach for bone repair and regeneration seeking to address limitations associated with current therapies, such as autologous bone grafting. While many bone tissue engineering approaches have traditionally focused on synthetic materials (such as polymers or hydrogels), there has been a lot of excitement surrounding the use of natural materials due to their biologically inspired properties. Fibrin is a natural scaffold formed following tissue injury that initiates hemostasis and provides the initial matrix useful for cell adhesion, migration, proliferation, and differentiation...
2017: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/28747073/the-osler-s-view-treating-comorbid-bipolar-disorder-and-obsessive-compulsive-disorder
#18
Andrea Amerio, Matteo Tonna, Anna Odone, S Nassir Ghaemi
No abstract text is available yet for this article.
July 1, 2017: Australian and New Zealand Journal of Psychiatry
https://www.readbyqxmd.com/read/28628969/comparative-induction-of-controlled-hypotension-by-electroacupuncture-at-du20-acupoint-and-remifentanil-in-lumbar-laminectomy
#19
Mehdi Ghaemi, Majid Ansari, Kourosh Amini
Hypotensive anesthesia is utilized to reduce bleeding during orthopedic surgery. One of the various drugs that have been used to reduce blood pressure is remifentanil. This study was an attempt to compare the effect of remifentanil with that of electroacupuncture (EA) at DU20 on reducing blood pressure. In this randomized controlled clinical trial, 54 patients undergoing lumbar laminectomy were allocated to two groups. Hypotensive anesthesia was performed through infusion of remifentanil 100 μg/kg/min for the control group, and EA at DU20 acupoint with a frequency of 2-10 Hz and intensity of 1-5 mA for the intervention group...
June 30, 2017: Chinese Journal of Physiology
https://www.readbyqxmd.com/read/28580046/characterization-of-microfluidic-clamps-for-immobilizing-and-imaging-of-drosophila-melanogaster-larva-s-central-nervous-system
#20
Reza Ghaemi, Pouya Rezai, Fatemeh Rafiei Nejad, Ponnambalam Ravi Selvaganapathy
Drosophila melanogaster is a well-established model organism to understand biological processes and study human diseases at the molecular-genetic level. The central nervous system (CNS) of Drosophila larvae is widely used as a model to study neuron development and network formation. This has been achieved by using various genetic manipulation tools such as microinjection to knock down certain genes or over-express proteins for visualizing the cellular activities. However, visualization of an intact-live neuronal response in larva's Central Nervous System (CNS) is challenging due to robust digging/burrowing behaviour that impedes neuroimaging...
May 2017: Biomicrofluidics
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