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https://www.readbyqxmd.com/read/29166687/-how-probable-is-it-that-seniors-using-an-e-bike-will-have-an-accident-a-new-health-care-topic-also-for-consulting-doctors
#1
Raphael Weiss, Christian Juhra, Britta Wieskötter, Udo Weiss, Susanne Jung, Michael Raschke
Background In Germany there are more than 70 million bicycles. Because of technical progress, over 200,000 electro-assisted bikes were sold in Germany in 2010 alone. In 2013, the number increased to 410,000. Currently more than 1.6 million electric bicycles are used here. One of the largest user groups are seniors. Accident researchers fear an increased risk of accidents/injuries. Methods For one year, all cycling accidents involving electric bicycles and senior citizens were collected and analysed in 23 hospitals of the TraumaNetwork NorthWest and by the local police authorities...
November 22, 2017: Zeitschrift Für Orthopädie und Unfallchirurgie
https://www.readbyqxmd.com/read/29165596/molecular-relatedness-of-esbl-ampc-producing-escherichia-coli-from-humans-animals-food-and-the-environment-a-pooled-analysis
#2
Alejandro Dorado-García, Joost H Smid, Wilfrid van Pelt, Marc J M Bonten, Ad C Fluit, Gerrita van den Bunt, Jaap A Wagenaar, Joost Hordijk, Cindy M Dierikx, Kees T Veldman, Aline de Koeijer, Wietske Dohmen, Heike Schmitt, Apostolos Liakopoulos, Ewa Pacholewicz, Theo J G M Lam, Annet G Velthuis, Annet Heuvelink, Maaike A Gonggrijp, Engeline van Duijkeren, Angela H A M van Hoek, Ana Maria de Roda Husman, Hetty Blaak, Arie H Havelaar, Dik J Mevius, Dick J J Heederik
Background: In recent years, ESBL/AmpC-producing Escherichia coli (ESBL/AmpC-EC) have been isolated with increasing frequency from animals, food, environmental sources and humans. With incomplete and scattered evidence, the contribution to the human carriage burden from these reservoirs remains unclear. Objectives: To quantify molecular similarities between different reservoirs as a first step towards risk attribution. Methods: Pooled data on ESBL/AmpC-EC isolates were recovered from 35 studies in the Netherlands comprising >27 000 samples, mostly obtained between 2005 and 2015...
November 18, 2017: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/29165352/antibody-based-protective-immunity-against-helminth-infections-antibody-phage-display-derived-antibodies-against-bmr1-antigen
#3
Anizah Rahumatullah, Izzati Zahidah Abdul Karim, Rahmah Noordin, Theam Soon Lim
Helminth parasite infections are significantly impacting global health, with more than two billion infections worldwide with a high morbidity rate. The complex life cycle of the nematodes has made host immune response studies against these parasites extremely difficult. In this study, we utilized two phage antibody libraries; the immune and naïve library were used to identify single chain fragment variable (scFv) clones against a specific filarial antigen (BmR1). The V-gene analysis of isolated scFv clones will help shed light on preferential VDJ gene segment usage against the filarial BmR1 antigen in healthy and infected states...
November 22, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29165175/triglycerides-and-blood-pressure-in-relation-to-circulating-cd34-positive-cell-levels-among-community-dwelling-elderly-japanese-men-a-cross-sectional-study
#4
Yuji Shimizu, Shimpei Sato, Yuko Noguchi, Jun Koyamatsu, Hirotomo Yamanashi, Mako Nagayoshi, Koichiro Kadota, Shin-Ya Kawashiri, Yasuhiro Nagata, Takahiro Maeda
BACKGROUND: Triglycerides are reported to be positively associated with blood pressure (both systolic and diastolic). However, in a previous study, we reported a significant positive association between triglycerides and circulating CD34-positive cells (endothelial repair) among non-hypertensive, but not hypertensive, participants. Since hypertension and endothelial dysfunction have a bi-directional association (vicious cycle), the status of circulating CD34-positive cells may influence the association between triglycerides and hypertension...
November 21, 2017: Environmental Health and Preventive Medicine
https://www.readbyqxmd.com/read/29164802/use-of-bacillus-thuringiensis-israelensis-in-integrated-vector-control-of-aedes-sp-in-sri-lanka-a-prospective-controlled-effectiveness-study
#5
H A Tissera, P C Samaraweera, B D W Jayamanne, M D S Janaki, M P P U Chulasiri, C Rodrigo, S D Fernando
OBJECTIVES: The annual incidence of dengue has been increasing over the last few years in Sri Lanka with seasonal epidemics. Biological control of the vector has not been part of the integrated vector control implemented by the public health authorities of Sri Lanka so far. This pilot study assessed the effectiveness of using Bacillus thuringiensis israelensis (Bti) spray to control the Aedes mosquito vector population density. METHODS: Prospective controlled effectiveness study in 3 administrative divisions of Colombo...
November 22, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/29164664/can-sleep-quality-and-burnout-affect-the-job-performance-of-shift-work-nurses-a-hospital-cross-sectional-study
#6
Fabio Giorgi, Antonella Mattei, Ippolito Notarnicola, Cristina Petrucci, Loreto Lancia
AIM: The aim of this study was to investigate any possible relationship between sleep disorders, burnout and job performance in a shift-work population of nurses. BACKGROUND: Sleep disorders and burnout can affect the job performance of nurses in terms of efficiency, productivity, task execution speed and supervision, which can be compromised when work shifts are organized on a 24-hour schedule and when the shift itself is irregular. DESIGN: A cross-sectional observational study was conducted from August 2014 - January 2015 on a sample of 315 shift-work nurses across 39 wards in seven central Italian hospitals...
November 22, 2017: Journal of Advanced Nursing
https://www.readbyqxmd.com/read/29164456/the-effect-of-animal-grazing-on-vegetation-and-soil-and-element-cycling-in-nature
#7
Krzysztof Głowacz, Roman Niżnikowski
Appropriate level of bio-components in blood plasma of animals is associated with their concentration in soil and in green fodder. Cycling of elements in nature and their adequate level in animal organisms result in proper functioning of an organism as a whole (Khan et al. 68:279-284, 2007). Therefore, it is important to analyse soil and green fodder for these components. If some deficits are found, it is important to supplement components responsible for e.g. proper growth and development of a young organism, proper reproduction and, consequently, good quality of obtained product, which may affect human health (Minzanova et al...
November 21, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29164422/efficient-production-and-secretion-of-oxaloacetate-from-halomonas-sp-km-1-under-aerobic-conditions
#8
Asuka Hannya, Taku Nishimura, Isao Matsushita, Jun Tsubota, Yoshikazu Kawata
The alkaliphilic, halophilic bacterium Halomonas sp. KM-1 can utilize glucose for the intracellular storage of the bioplastic poly-(R)-3-hydroxybutyric acid (PHB) and extracellular secretion of pyruvate under aerobic conditions. In this study, we investigated the effects of sodium chloride concentration on PHB accumulation and pyruvate secretion in the KM-1 strain and, unexpectedly, observed that oxaloacetate, an important intermediate chemical in the TCA cycle, glycogenesis, and aspartic acid biosynthesis, was secreted...
November 21, 2017: AMB Express
https://www.readbyqxmd.com/read/29162935/hepatitis-e-virus-advances-and-challenges
#9
REVIEW
Ila Nimgaonkar, Qiang Ding, Robert E Schwartz, Alexander Ploss
At least 20 million hepatitis E virus (HEV) infections occur annually, with >3 million symptomatic cases and ∼60,000 fatalities. Hepatitis E is generally self-limiting, with a case fatality rate of 0.5-3% in young adults. However, it can cause up to 30% mortality in pregnant women in the third trimester and can become chronic in immunocompromised individuals, such as those receiving organ transplants or chemotherapy and individuals with HIV infection. HEV is transmitted primarily via the faecal-oral route and was previously thought to be a public health concern only in developing countries...
November 22, 2017: Nature Reviews. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29162422/chlamydiales-anaplasma-and-bartonella-persistence-and-immune-escape-of-intracellular-bacteria
#10
Aurélie Scherler, Nicolas Jacquier, Gilbert Greub
Intracellular bacteria, such as Chlamydiales, Anaplasma or Bartonella, need to persist inside their host in order to complete their developmental cycle and to infect new hosts. In order to escape from the host immune system, intracellular bacteria have developed diverse mechanisms of persistence, which can directly impact the health of their host.
November 18, 2017: Microbes and Infection
https://www.readbyqxmd.com/read/29161238/downregulation-of-inhibition-of-apoptosis-stimulating-protein-of-p53-iaspp-suppresses-cisplatin-resistant-gastric-carcinoma-in-vitro
#11
Jianyong Yu, Li Li, Chengsuo Huang
BACKGROUND Gastric cancer (GC) with cisplatin resistance is one of the leading causes of limitations to therapy. Inhibition of apoptosis-stimulating protein of p53 (iASPP) plays a key role in GC. However, the role of iASPP in GC with cisplatin resistance remains unclear. The aim of this study was to investigate iASPP expression in GC, and the functions of iASPP in cisplatin-resistant cell lines. MATERIAL AND METHODS In this study, the expression of iASPP was investigated in normal GC patients and patients with cisplatin resistance, along with GC cell lines and cell lines with cisplatin resistance...
November 21, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29161069/characteristics-of-hiv-positive-transgender-men-receiving-medical-care-united-states-2009-2014
#12
Ansley Lemons, Linda Beer, Teresa Finlayson, Donna Hubbard McCree, Daniel Lentine, R Luke Shouse
OBJECTIVES: To present the first national estimate of the sociodemographic, clinical, and behavioral characteristics of HIV-positive transgender men receiving medical care in the United States. METHODS: This analysis included pooled interview and medical record data from the 2009 to 2014 cycles of the Medical Monitoring Project, which used a 3-stage, probability-proportional-to-size sampling methodology. RESULTS: Transgender men accounted for 0...
November 21, 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/29160444/family-context-and-the-physical-activity-of-adolescents-comparing-differences
#13
Cynthia Graciane Carvalho Ramos, Roseli Gomes de Andrade, Amanda Cristina de Souza Andrade, Amanda Paula Fernandes, Dário Alves da Silva Costa, César Coelho Xavier, Fernando Augusto Proietti, Waleska Teixeira Caiaffa
INTRODUCTION: Family context plays an important role with regard to the physical activity (PA) of adolescents. Intense changes in family composition, including an increase of single-parent structures can affect behavior. OBJECTIVE: To estimate the prevalence of PA, between boys and girls of 11-17 years old, and investigate its association with family context variables. METHODS: A cross-sectional population-based study "The BH Health Study" was conducted in two health districts of Belo Horizonte...
July 2017: Revista Brasileira de Epidemiologia, Brazilian Journal of Epidemiology
https://www.readbyqxmd.com/read/29160417/radiotherapy-modulates-expression-of-egfr-ercc1-and-p53-in-cervical-cancer
#14
V H de Almeida, A C de Melo, D D Meira, A C Pires, A Nogueira-Rodrigues, H K Pimenta-Inada, F G Alves, G Moralez, L S Thiago, C G Ferreira, C Sternberg
Cervical cancer is a public health problem and the molecular mechanisms underlying radioresistance are still poorly understood. Here, we evaluated the modulation of key molecules involved in cell proliferation, cell cycle and DNA repair in cervical cancer cell lines (CASKI and C33A) and in malignant tissues biopsied from 10 patients before and after radiotherapy. The expression patterns of epidermal growth factor receptor (EGFR), excision repair cross-complementation group 1 (ERCC1) and p53 were evaluated in cancer cell lines by quantitative PCR and western blotting, and in human malignant tissues by immunohistochemistry...
November 13, 2017: Brazilian Journal of Medical and Biological Research, Revista Brasileira de Pesquisas Médicas e Biológicas
https://www.readbyqxmd.com/read/29159015/meals-for-good-an-innovative-community-project-to-provide-healthy-meals-to-children-in-early-care-and-education-programs-through-food-bank-catering
#15
Leah R Carpenter, Teresa M Smith, Katherine Stern, Lisa Weissenburger-Moser Boyd, Cristy Geno Rasmussen, Kelly Schaffer, Julie Shuell, Karen Broussard, Amy L Yaroch
Innovative approaches to childhood obesity prevention are warranted in early care and education (ECE) settings, since intervening early among youth is recommended to promote and maintain healthy behaviors. The objective of the Meals for Good pilot was to explore feasibility of implementing a food bank-based catering model to ECE programs to provide more nutritious meals, compared to meals brought from home (a parent-prepared model). In 2014-2015, a 12-month project was implemented by a food bank in central Florida in four privately-owned ECE programs...
December 2017: Preventive Medicine Reports
https://www.readbyqxmd.com/read/29158725/nutritional-supplement-practices-of-professional-ugandan-athletes-a-cross-sectional-study
#16
Haruna Muwonge, Robert Zavuga, Peninnah Aligawesa Kabenge, Timothy Makubuya
Background: The use of nutritional supplements (NS) places athletes at great risk for inadvertent doping. Due to the paucity of data on supplement use, this study aimed to determine the proportion of Ugandan athletes using nutritional supplements and to investigate the athletes' motivation to use these supplements. Methods: A cross-sectional study was conducted in which an interviewer-administered questionnaire was used to collect data from 359 professional athletes participating in individual (boxing, cycling, athletics) and team (basketball, rugby, football, netball, and volleyball) sports...
2017: Journal of the International Society of Sports Nutrition
https://www.readbyqxmd.com/read/29156910/genetic-biomarkers-associated-with-changes-in-quality-of-life-and-pain-following-palliative-radiotherapy-in-patients-with-bone-metastases
#17
Anthony Furfari, Bo Angela Wan, Keyue Ding, Andrew Wong, Liting Zhu, Andrea Bezjak, Rebecca Wong, Carolyn F Wilson, Carlo DeAngelis, Azar Azad, Edward Chow, George S Charames
BACKGROUND: Patients with bone metastases undergoing palliative radiation therapy (RT) may experience changes in both the functional and symptomatic aspects of quality of life (QOL). The European Organization of Cancer Research and Treatment (EORTC) QOL Questionnaire Core-15 Palliative (QLQ-C15-PAL) is a validated questionnaire employed to assess QOL specifically in palliative patients. Our study aimed to identify single-nucleotide variant (SNV) genetic biomarkers associated with changes in QOL and pain...
September 28, 2017: Annals of Palliative Medicine
https://www.readbyqxmd.com/read/29156620/stretchable-highly-durable-ternary-nanocomposite-strain-sensor-for-structural-health-monitoring-of-flexible-aircraft
#18
Feng Yin, Dong Ye, Chen Zhu, Lei Qiu, YongAn Huang
Harmonious developments of electrical and mechanical performances are crucial for stretchable sensors in structural health monitoring (SHM) of flexible aircraft such as aerostats and morphing aircrafts. In this study, we prepared a highly durable ternary conductive nanocomposite made of polydimethylsiloxane (PDMS), carbon black (CB) and multi-walled carbon nanotubes (MWCNTs) to fabricate stretchable strain sensors. The nanocomposite has excellent electrical and mechanical properties by intensively optimizing the weight percentage of conducting fillers as well as the ratio of PDMS pre-polymer and curing agent...
November 20, 2017: Sensors
https://www.readbyqxmd.com/read/29156311/impacts-from-urban-water-systems-on-receiving-waters-how-to-account-for-severe-wet-weather-events-in-lca
#19
Eva Risch, Johnny Gasperi, Marie-Christine Gromaire, Ghassan Chebbo, Sam Azimi, Vincent Rocher, Philippe Roux, Ralph K Rosenbaum, Carole Sinfort
Sewage systems are a vital part of the urban infrastructure in most cities. They provide drainage, which protects public health, prevents the flooding of property and protects the water environment around urban areas. On some occasions sewers will overflow into the water environment during heavy rain potentially causing unacceptable impacts from releases of untreated sewage into the environment. In typical Life Cycle Assessment (LCA) studies of urban wastewater systems (UWS), average dry-weather conditions are modelled while wet-weather flows from UWS, presenting a high temporal variability, are not currently accounted for...
October 23, 2017: Water Research
https://www.readbyqxmd.com/read/29156189/obesity-in-pregnancy-optimizing-outcomes-for-mom-and-baby
#20
REVIEW
Heidi Dutton, Sarah Jean Borengasser, Laura Marie Gaudet, Linda A Barbour, Erin Joanne Keely
Obesity is common in women of childbearing age, and management of this population around the time of pregnancy involves specific challenges. Weight and medical comorbidities should be optimized both before and during pregnancy. During pregnancy, gestational weight gain should be limited, comorbidities should be appropriately screened for and managed, and fetal health should be monitored. Consideration should be given to the optimal timing of delivery and to reducing surgical and anesthetic complications. In the postpartum period, breastfeeding and weight loss should be promoted...
January 2018: Medical Clinics of North America
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