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https://www.readbyqxmd.com/read/29355291/objectively-measured-physical-activity-of-hospital-shift-workers
#1
Bette Loef, Allard J van der Beek, Andreas Holtermann, Gerben Hulsegge, Debbie van Baarle, Karin I Proper
Objectives Shift work may alter workers' leisure-time and occupational physical activity (PA) levels, which might be one of the potential underlying mechanisms of the negative health effects of shift work. Therefore, we compared objectively measured PA levels between hospital shift and non-shift workers. Methods Data were used from Klokwerk+, a cohort study examining the health effects of shift work among healthcare workers employed in hospitals. In total, 401 shift workers and 78 non-shift workers were included, all of whom wore Actigraph GT3X accelerometers for up to seven days...
January 22, 2018: Scandinavian Journal of Work, Environment & Health
https://www.readbyqxmd.com/read/29354659/chikungunya-outbreak-in-kedougou-southeastern-senegal-in-2009-2010
#2
Abdourahmane Sow, Oumar Faye, Mawlouth Diallo, Diawo Diallo, Rubing Chen, Ousmane Faye, Cheikh T Diagne, Mathilde Guerbois, Manfred Weidmann, Youssoupha Ndiaye, Cheikh Sadibou Senghor, Abdourahmane Faye, Ousmane M Diop, Bakary Sadio, Oumar Ndiaye, Douglas Watts, Kathryn A Hanley, Anta T Dia, Denis Malvy, Scott C Weaver, Amadou Alpha Sall
Background: In Senegal, Chikungunya virus (CHIKV), which is an emerging mosquito-borne alphavirus, circulates in a sylvatic and urban/domestic cycle and has caused sporadic human cases and epidemics since 1960s. However, the real impact of the CHIKV sylvatic cycle in humans and mechanisms underlying its emergence still remains unknown. Methodology: One thousand four hundred nine suspect cases of CHIKV infection, recruited from 5 health facilities located in Kedougou region, south-eastern Senegal, between May 2009 to March 2010, together with 866 serum samples collected from schoolchildren from 4 elementary schools in May and November 2009 from Kedougou were screened for anti-CHIKV immunoglobulin (Ig)M antibodies and, when appropriate, for viral nucleic acid by real-time polymerase chain reaction (rPCR) and virus isolation...
January 2018: Open Forum Infectious Diseases
https://www.readbyqxmd.com/read/29353698/seasonal-pattern-of-anthropogenic-salinization-in-temperate-forested-headwater-streams
#3
Anthony J Timpano, Carl E Zipper, David J Soucek, Stephen H Schoenholtz
Salinization of freshwaters by human activities is of growing concern globally. Consequences of salt pollution include adverse effects to aquatic biodiversity, ecosystem function, human health, and ecosystem services. In headwater streams of the temperate forests of eastern USA, elevated specific conductance (SC), a surrogate measurement for the major dissolved ions composing salinity, has been linked to decreased diversity of aquatic insects. However, such linkages have typically been based on limited numbers of SC measurements that do not quantify intra-annual variation...
January 8, 2018: Water Research
https://www.readbyqxmd.com/read/29353544/a-comprehensive-profile-of-those-who-have-health-related-apps
#4
Jiyoung Chae
This study investigated sociodemographic, health-related, technological, and motivational factors associated with having health-related apps. Focusing on motivational factors, this study chose five general healthy intentions (about fruit, vegetable, and soda intake, weight control, and amount of exercise) and examined whether those with intention to change their current state (change group) differ from those who want to maintain (maintain group) or pay no attention to their current state (no attention group)...
January 1, 2018: Health Education & Behavior: the Official Publication of the Society for Public Health Education
https://www.readbyqxmd.com/read/29352147/pre-conception-maternal-erythrocyte-saturated-to-unsaturated-fatty-acid-ratio-predicts-pregnancy-after-natural-cycle-frozen-embryo-transfer
#5
Christopher C Onyiaodike, Heather M Murray, Ruiqi Zhang, Barbara J Meyer, Fiona Jordan, E Ann Brown, Robert J B Nibbs, Helen Lyall, Naveed Sattar, Scott M Nelson, Dilys J Freeman
The environment for embryo implantation and fetal growth and development is affected by maternal nutritional, metabolic and health status. The aim of this prospective, cohort study was to test whether plasma metabolic and inflammatory biomarkers can predict pregnancy resulting from in vitro fertilisation (IVF). Women with a natural menstrual cycle undergoing frozen embryo transfer (FET) were recruited and fasting baseline blood samples were collected a mean of 3.4 days prior to the luteinising hormone (LH) surge and a non-fasting blood sample was taken on the day of FET...
January 19, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29352027/the-thalamus-in-drug-addiction-from-rodents-to-humans
#6
REVIEW
Anna S Huang, Jameson A Mitchell, Suzanne N Haber, Nelly Alia-Klein, Rita Z Goldstein
Impairments in response inhibition and salience attribution (iRISA) have been proposed to underlie the clinical symptoms of drug addiction as mediated by cortico-striatal-thalamo-cortical networks. The bulk of evidence supporting the iRISA model comes from neuroimaging research that has focused on cortical and striatal influences with less emphasis on the role of the thalamus. Here, we highlight the importance of the thalamus in drug addiction, focusing on animal literature findings on thalamic nuclei in the context of drug-seeking, structural and functional changes of the thalamus as measured by imaging studies in human drug addiction, particularly during drug cue and non-drug reward processing, and response inhibition tasks...
March 19, 2018: Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
https://www.readbyqxmd.com/read/29351857/psychometric-properties-of-outcome-measures-evaluating-decline-in-gait-in-cerebellar-ataxia-a-systematic-review
#7
REVIEW
Sarah C Milne, Anna Murphy, Nellie Georgiou-Karistianis, Eppie M Yiu, Martin B Delatycki, Louise A Corben
Cerebellar ataxia often results in impairment in ambulation secondary to gait pattern dysfunction and compensatory gait adjustments. Pharmaceutical and therapy-based interventions with potential benefit for gait in ataxia are starting to emerge, however evaluation of such interventions is hampered by the lack of outcome measures that are responsive, valid and reliable for measurement of gait decline in cerebellar ataxia. This systematic review aimed for the first time to evaluate the psychometric properties of gait and walking outcomes applicable to individuals with cerebellar ataxia...
January 4, 2018: Gait & Posture
https://www.readbyqxmd.com/read/29351477/mathematical-analysis-of-circadian-disruption-and-metabolic-re-entrainment-of-hepatic-gluconeogenesis-the-intertwining-entraining-roles-of-light-and-feeding
#8
Seul-A Bae, Ioannis P Androulakis
The circadian rhythms influence the metabolic activity from molecular level to tissue, organ, and host level. Disruption of the circadian rhythms manifest to the host's health as metabolic syndromes including obesity, diabetes, and elevated plasma glucose, eventually leading to cardiovascular diseases. Therefore, it is imperative to understand the mechanism behind the relationship between circadian rhythms and metabolism. To start answering this question, we propose a semi-mechanistic mathematical model to study the effect of circadian disruption on hepatic gluconeogenesis in humans...
January 9, 2018: American Journal of Physiology. Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29351413/mitochondrial-content-is-preserved-throughout-disease-progression-in-the-mdx-mouse-model-of-duchenne-muscular-dystrophy-regardless-of-taurine-supplementation
#9
Robert G Barker, Victoria L Wyckelsma, Hongyang Xu, Robyn M Murphy
Mitochondrial dysfunction is a pathological feature of Duchenne muscular Dystrophy (DMD), a debilitating and fatal neuromuscular disorder characterised by progressive muscle wasting and weakness. Mitochondria are a source of cellular ATP and involved in Ca2+ regulation and apoptotic signalling. Ameliorating aberrant mitochondrial function has therapeutic potential for reducing DMD disease severity. The dystrophic mdx mouse exhibits peak muscle damage at 21-28d which stabilises after 8 weeks. The amino acid taurine is implicated in mitochondrial health and function, with endogenous concentrations low when measured during the cycle of peak muscle damage in mdx mice...
December 20, 2017: American Journal of Physiology. Cell Physiology
https://www.readbyqxmd.com/read/29351130/comparative-effectiveness-of-low-volume-time-efficient-resistance-training-versus-endurance-training-in-patients-with-heart-failure
#10
Gregers Winding Munch, Jaya Birgitte Rosenmeier, Morten Petersen, Anders Rasmussen Rinnov, Ulrik Winning Iepsen, Bente Klarlund Pedersen, Stefan Peter Mortensen
PURPOSE: Cardiorespiratory fitness is positively related to heart failure (HF) prognosis, but lack of time and low energy are barriers for adherence to exercise. We, therefore, compared the effect of low-volume time-based resistance exercise training (TRE) with aerobic moderate-intensity cycling (AMC) on maximal and submaximal exercise capacity, health-related quality of life, and vascular function. METHODS: Twenty-eight HF patients (New York Heart Association class I-II) performed AMC (n = 14) or TRE (n = 14)...
January 18, 2018: Journal of Cardiopulmonary Rehabilitation and Prevention
https://www.readbyqxmd.com/read/29349777/in-bed-cycling-in-the-icu-patient-safety-and-recollections-with-motivational-effects
#11
M Ringdal, M Warren Stomberg, K Egnell, E Wennberg, R Zätterman, C Rylander
BACKGROUND: In-bed cycling (IBC) is gaining interest for implementation in intensive care units. Our main objective was to explore patient recollections and experiences of early mobilization, including IBC. Secondly, we aimed to examine if IBC was safe and feasible. METHODS: Eleven participants were interviewed about their experiences during their critical illnesses and active mobilization in the intensive care unit. The interviews were analyzed thematically. Six participants were also monitored for physiological reactions and adverse events during IBC while mechanically ventilated...
January 18, 2018: Acta Anaesthesiologica Scandinavica
https://www.readbyqxmd.com/read/29347935/real-world-experience-of-women-using-extended-cycle-vs-monthly-cycle-combined-oral-contraception-in-the-united-states-the-national-health-and-wellness-survey
#12
Rossella E Nappi, Iñaki Lete, Lulu K Lee, Natalia M Flores, Marie-Christine Micheletti, Boxiong Tang
BACKGROUND: The real-world experience of women receiving extended-cycle combined oral contraception (COC) versus monthly-cycle COC has not been reported. METHODS: Data were from the United States 2013 National Health and Wellness Survey. Eligible women (18-50 years old, premenopausal, without hysterectomy) currently using extended-cycle COC (3 months between periods) were compared with women using monthly-cycle COC. Treatment satisfaction (1 "extremely dissatisfied" to 7 "extremely satisfied"), adherence (8-item Morisky Medication Adherence Scale©), menstrual cycle-related symptoms, health-related quality of life (HRQOL) and health state utilities (Medical Outcomes Short Form Survey-36v2®), depression (9-item Patient Health Questionnaire), sleep difficulties, Work Productivity and Activity Impairment-General Health, and healthcare resource use were assessed using one-way analyses of variance, chi-square tests, and generalized linear models (adjusted for covariates)...
January 18, 2018: BMC Women's Health
https://www.readbyqxmd.com/read/29347394/linking-biological-and-physical-aging-dynamical-scaling-of-multicellular-regeneration
#13
Yuting Lou, Jufeng Xia, Wei Tang, Yu Chen
The fight against biological aging (bio-aging) is long-standing, with the focus of intense research aimed at maintaining high rates of tissue regeneration to promote health and longevity. Nevertheless, there are overwhelming complexities associated with the quantitative analysis of aging. In this study, we sought to quantify bio-aging based on physical aging, by mapping instances of multicellular regeneration to the relaxation of physical systems. An experiment of delayed wound healing assays was devised to obtain delay-dependent healing data...
December 2017: Physical Review. E
https://www.readbyqxmd.com/read/29345727/the-petal-project-an-innovation-in-sexual-healthcare-and-education-for-kenyan-schoolgirl
#14
Karen M Parker
In the western province of Nyanza in Kenya, girls and women face an issue all too common in the developing world-little or no access to affordable means to effectively managing their menstrual flow. As a result, many stay at home or drop out of school because they are teased and embarrassed. Some approach men for money to buy pads and are forced, in return, to engage in transactional sex. The girls may not be able to return to school at all due to pregnancy. The story literally and figuratively continues to cycle, keeping girls in positions of dependency and poverty...
January 18, 2018: Nursing Forum
https://www.readbyqxmd.com/read/29344657/effects-of-hereditary-moderate-high-fat-diet-on-metabolic-performance-and-physical-endurance-capacity-in-c57bl-6-offspring
#15
Fang Liu, Guirong Zhang, Xue Sheng, Shang Liu, Meng Cui, Heyun Guo, Jianbin Xue, Lingyun Zhang
Obesity in pregnant women presents a risk to fetal health, leading to numerous metabolic syndromes and chronic inflammation risks. Previously, physical exercise was considered to be one of the primary treatments for obesity. However, the effect of fat consumption throughout the life cycle on physical endurance capacity remains unknown. A total of two groups of female mice (age, 6 weeks; C57BL/6J) were fed with a normal chow diet and a moderate high fat diet (MHFD), during pregnancy and lactation (8 weeks), with the offspring receiving the same diet as the mother...
January 16, 2018: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29344082/implementing-guidelines-on-physical-health-in-the-acute-mental-health-setting-a-quality-improvement-approach
#16
Stuart Green, Ed Beveridge, Liz Evans, Jenny Trite, Sandra Jayacodi, Rachel Evered, Caroline Parker, Luca Polledri, Emily Tabb, John Green, Anton Manickam, Joanna Williams, Rebecca Deere, Bill Tiplady
Background: In the UK, life expectancy for people living with a serious mental illness, such as schizophrenia and bipolar disorder, is reduced by 15-20 years compared with the general population. In recent years, evidence based guidelines/policies designed to improve their physical health have been published, yet a gap remains between recommendations and practice. This case study describes how guidelines to support physical health were implemented using a quality improvement approach...
2018: International Journal of Mental Health Systems
https://www.readbyqxmd.com/read/29343977/cost-effectiveness-analysis-of-six-therapies-for-the-treatment-of-lower-urinary-tract-symptoms-due-to-benign-prostatic-hyperplasia
#17
James C Ulchaker, Melissa S Martinson
Objective: To conduct a cost-effectiveness analysis from payers' perspectives of six treatments for lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH) and to examine positioning of these modalities in the marketplace for the best use of health care funds and quality-of-life benefits for patients. Methods: The economic analysis was conducted with a Markov model to compare combination prescription drug therapy (ComboRx), minimally invasive therapies (MITs) including convective radiofrequency (RF) water vapor thermal therapy (Rezūm®), conductive RF thermal therapy (Prostiva®), and prostatic urethral lift (UroLift®), and invasive surgical procedures including photovaporization of the prostate (Greenlight® PVP) and transurethral resection of the prostate (TURP)...
2018: ClinicoEconomics and Outcomes Research: CEOR
https://www.readbyqxmd.com/read/29343412/implementing-genome-driven-personalized-cardiology-in-clinical-practice
#18
REVIEW
Ares Pasipoularides
Genomics designates the coordinated investigation of a large number of genes in the context of a biological process or disease. It may be long before we attain comprehensive understanding of the genomics of common complex cardiovascular diseases (CVDs) such as inherited cardiomyopathies, valvular diseases, primary arrhythmogenic conditions, congenital heart syndromes, hypercholesterolemia and atherosclerotic heart disease, hypertensive syndromes, and heart failure with preserved/reduced ejection fraction. Nonetheless, as genomics is evolving rapidly, it is constructive to survey now pertinent concepts and breakthroughs...
January 14, 2018: Journal of Molecular and Cellular Cardiology
https://www.readbyqxmd.com/read/29342208/comparison-of-traffic-injury-related-hospitalisation-between-bicyclists-and-motorcyclists-in-taiwan
#19
Chih-Wei Pai, Hsiao-Yu Lin, Shin-Han Tsai, Ping-Ling Chen
OBJECTIVES: Bicyclists and motorcyclists contribute substantially to the morbidity and mortality rates of road crash casualties. The objective of the study was to investigate the crash characteristics of bicyclist and motorcyclist casualties presented to hospitals in Taiwan resulting from crashes. METHODS: By using linked data from The National Traffic Crash Dataset and the National Health Insurance Database between 2003 and 2012, logistic regression models were used to examine the determinants of hospitalisation among motorcyclist and bicyclist casualties...
2018: PloS One
https://www.readbyqxmd.com/read/29342096/high-resolution-lipidomics-of-the-early-life-stages-of-the-red-seaweed-porphyra-dioica
#20
Elisabete da Costa, Vitor Azevedo, Tânia Melo, Andreia M Rego, Dmitry V Evtuguin, Pedro Domingues, Ricardo Calado, Rui Pereira, Maria H Abreu, Maria R Domingues
Porphyra dioica is a commercial seaweed consumed all over the world, mostly in the shape of nori sheets used for "sushi" preparation. It is a well-known part of the Asian diet with health benefits, which have been associated, among others, to the high levels of n-3 and n-6 fatty acids in this red alga. However, other highly valued lipids of Porphyra are polar lipids that remain largely undescribed and can have both nutritional value and bioactivity, thus could contribute to the valorization of this seaweed...
January 17, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
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