Loïc Chollet, Séverine Heumel, Lucie Deruyter, Fabrice Bouilloux, Lou Delval, Véronique Robert, Marie-Hélène Gevaert, Muriel Pichavant, Valentin Sencio, Cyril Robil, Isabelle Wolowczuk, Harry Sokol, Sandrine Auger, Alexandre Douablin, Philippe Langella, Jean-Marc Chatel, Corinne Grangette, François Trottein
The gut-lung axis is critical during viral respiratory infections such as influenza. Gut dysbiosis during infection translates into a massive drop of microbially produced short-chain fatty acids (SCFAs). Among them, butyrate is important during influenza suggesting that microbiome-based therapeutics targeting butyrate might hold promises. The butyrate-producing bacterium Faecalibacterium duncaniae (formerly referred to as F. prausnitzii ) is an emerging probiotic with several health-promoting characteristics...
2024: Frontiers in Immunology