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Probiotics critical

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https://www.readbyqxmd.com/read/27850100/460-using-probiotics-in-the-critically-ill-a-meta-analysis-of-2-808-patients
#1
Connie Wang, Rahul Chaudhary, Sheri Berg
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27849120/review-gut-microbiota-and-functional-diseases-of-the-gastrointestinal-tract
#2
Nicola Imperatore, Raffaella Tortora, Filomena Morisco, Nicola Caporaso
INTRODUCTION: Functional gastrointestinal disorders (FGIDs) are a common group of chronic gastrointestinal (GI) diseases defined by symptom-based diagnostic criteria, which consider chronic or recurrent symptoms of the GI tract in the absence of other organic or biochemical reasons. Recent evidences have been highlighted the role of gut microbiota in the pathophysiology of the FGIDs. EVIDENCE ACQUISITION: We focused our attention on critically analysis of the existing literature on the role of gut microbiota in FGIDs, by evaluating the differences of composition, functions and role of intestinal flora in FGIDs of the upper and lower gastrointestinal tract...
November 16, 2016: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/27821203/ageing-alters-the-impact-of-nutrition-on-immune-function
#3
Parveen Yaqoob
Immunosenescence during ageing is a major challenge which weakens the ability of older individuals to respond to infection or vaccination. There has been much interest in dietary strategies to improve immunity in older people, but there is an assumption that modulation of the immune response in older people will be based on the same principles as for younger adults. Recent evidence suggests that ageing fundamentally alters the impact of nutrition on immune function. As a result, interpretation of data from studies investigating the impact of diet on immune function is highly dependent on subject age...
November 8, 2016: Proceedings of the Nutrition Society
https://www.readbyqxmd.com/read/27790434/diversity-of-vaginal-lactic-acid-bacterial-microbiota-in-15-algerian-pregnant-women-with-and-without-bacterial-vaginosis-by-using-culture-independent-method
#4
Souad Alioua, Akila Abdi, Imène Fhoula, Françoise Bringel, Abdelatif Boudabous, Imene Hadda Ouzari
INTRODUCTION: Bacterial Vaginosis (BV) is the most common lower genital tract disorder among women of reproductive age (pregnant and non-pregnant) and a better knowledge of Lactobacillus species richness in healthy and infected vaginal microbiota is needed to efficiently design better probiotic products to promote the maintenance of normal flora which will help prevent bacterial vaginosis. AIM: To evaluate and compare the diversity of lactic acid bacterial species in pregnant women with and without BV...
September 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27771302/blurred-lines-dysbiosis-and-probiotics-in-the-intensive-care-unit
#5
Lee E Morrow, Paul Wischmeyer
Clinicians have traditionally dichotomized bacteria as friendly commensals or harmful pathogens. However, the line separating the two has become blurred with the recognition that the intestinal microbiome is a complex entity wherein species can shift sides - from friend to foe and back again - based on crucial factors in their local environment. Significant disruptions in the homeostasis of the microbiome, a phenomenon called 'dysbiosis,' is increasingly associated with a host of untoward effects. Intensive care unit patients are at high risk for dysbiosis given high rates of antibiotic use, acute changes in diet, and the stress of critical illness...
October 19, 2016: Chest
https://www.readbyqxmd.com/read/27770467/pre-and-probiotics-for-allergy-prevention-time-to-revisit-recommendations
#6
REVIEW
A Forsberg, C E West, S L Prescott, M C Jenmalm
Reduced intensity and diversity of microbial exposure is considered a major factor driving abnormal postnatal immune maturation and increasing allergy prevalence, particularly in more affluent regions. Quantitatively, the largest important source of early immune-microbial interaction, the gut microbiota, is of particular interest in this context, with variations in composition and diversity in the first months of life associated with subsequent allergy development. Attempting to restore the health consequences of the 'dysbiotic drift' in modern society, interventions modulating gut microbiota for allergy prevention have been evaluated in several randomized placebo-controlled trials...
December 2016: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/27757227/new-insights-into-therapeutic-strategies-for-gut-microbiota-modulation-in-inflammatory-diseases
#7
Angélica Thomaz Vieira, Claudio Fukumori, Caroline Marcantonio Ferreira
The interaction between the gut microbiota and the host immune system is very important for balancing and resolving inflammation. The human microbiota begins to form during childbirth; the complex interaction between bacteria and host cells becomes critical for the formation of a healthy or a disease-promoting microbiota. C-section delivery, formula feeding, a high-sugar diet, a high-fat diet and excess hygiene negatively affect the health of the microbiota. Considering that the majority of the global population has experienced at least one of these factors that can lead to inflammatory disease, it is important to understand strategies to modulate the gut microbiota...
June 2016: Clinical & Translational Immunology
https://www.readbyqxmd.com/read/27735025/epidemiological-evaluation-of-acute-gastroenteritis-and-therapeutic-approaches-in-middle-east-countries
#8
D Ayoub, L R Lopetuso, F Chamseddine, A Dajani, K Lahiri, H Mahmoud, M S Miqdady, G Zirizzotti, M A Sultan, F Franceschi, A Gasbarrini
OBJECTIVE: Gastroenteritis represents with respiratory tract infection the most common infectious disease syndrome of humans in developing countries. Gut microbiota regional variation and dysbiosis play a crucial role in triggering and worsening this devastating GI disease. MATERIALS AND METHODS: With this manuscript, we want to explore and emphasize the critical aspect of acute gastroenteritis in Middle-East Countries and its correlation with the clinical aspect of gut microbiota modification and intestinal homeostasis...
September 2016: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/27726803/reducing-foodborne-pathogen-persistence-and-transmission-in-animal-production-environments-challenges-and-opportunities
#9
Elaine D Berry, James E Wells
Preharvest strategies to reduce zoonotic pathogens in food animals are important components of the farm-to-table food safety continuum. The problem is complex; there are multiple pathogens of concern, multiple animal species under different production and management systems, and a variety of sources of pathogens, including other livestock and domestic animals, wild animals and birds, insects, water, and feed. Preharvest food safety research has identified a number of intervention strategies, including probiotics, direct-fed microbials, competitive exclusion cultures, vaccines, and bacteriophages, in addition to factors that can impact pathogens on-farm, such as seasonality, production systems, diet, and dietary additives...
August 2016: Microbiology Spectrum
https://www.readbyqxmd.com/read/27717968/beneficial-microorganisms-for-honey-bees-problems-and-progresses
#10
Daniele Alberoni, Francesca Gaggìa, Loredana Baffoni, Diana Di Gioia
Nowadays, honey bees are stressed by a number of biotic and abiotic factors which may compromise to some extent the pollination service and the hive productivity. The EU ban of antibiotics as therapeutic agents against bee pathogens has stimulated the search for natural alternatives. The increasing knowledge on the composition and functions of the bee gut microbiota and the link between a balanced gut microbiota and health status have encouraged the research on the use of gut microorganisms to improve bee health...
October 8, 2016: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/27697444/probiotic-treatment-with-a-gut-symbiont-leads-to-parasite-susceptibility-in-honey-bees
#11
Konstantin Schmidt, Philipp Engel
Gut symbionts are critical for host health and as such might be used as probiotics. In a recent study, Schwarz et al. showed that pretreatment of honey bees with a dominant gut bacterium causes dysbiosis and increases pathogen susceptibility, showing that probiotic applications for animal health can have unwanted effects.
September 30, 2016: Trends in Parasitology
https://www.readbyqxmd.com/read/27681377/investigation-of-streptococcus-salivarius-mediated-inhibition-of-pneumococcal-adherence-to-pharyngeal-epithelial-cells
#12
Jayne Manning, Eileen M Dunne, Philip A Wescombe, John D F Hale, E Kim Mulholland, John R Tagg, Roy M Robins-Browne, Catherine Satzke
BACKGROUND: Pneumococcal adherence to the nasopharyngeal epithelium is a critical step in colonisation and disease. The probiotic bacterium, Streptococcus salivarius, can inhibit pneumococcal adherence to epithelial cells in vitro. We investigated the mechanism(s) of inhibition using a human pharyngeal epithelial cell line (Detroit 562) following pre-administration of two different strains of S. salivarius. RESULTS: Whilst the bacteriocin-encoding megaplasmids of S...
September 29, 2016: BMC Microbiology
https://www.readbyqxmd.com/read/27622371/probiotics-for-the-treatment-of-symptomatic-uncomplicated-diverticular-disease-rationale-and-current-evidence
#13
Carmelo Scarpignato, Anna Bertelé, Antonio Tursi
Changes in the colonic microbiota are critical to the pathogenesis of diverticular complications such as diverticulitis and peridiverticular abscesses. However, more subtle changes in microbiota composition may well be important to the more chronic manifestations of diverticulosis. Some studies have shown the presence of bacterial overgrowth in subgroups of patients with diverticular disease and recent studies, using molecular biology techniques, found an increase of proteobacteria and actinobacteria in patients with symptomatic uncomplicated diverticular disease (SUDD), compared with healthy controls...
October 2016: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/27621812/individual-strains-of-lactobacillus-paracasei-differentially-inhibit-human-basophil-and-mouse-mast-cell-activation
#14
Lydie Cassard, Ana Inés Lalanne, Peggy Garault, Aurélie Cotillard, Christian Chervaux, Michiel Wels, Tamara Smokvina, Marc Daëron, Raphaëlle Bourdet-Sicard
INTRODUCTION: The microbiota controls a variety of biological functions, including immunity, and alterations of the microbiota in early life are associated with a higher risk of developing allergies later in life. Several probiotic bacteria, and particularly lactic acid bacteria, were described to reduce both the induction of allergic responses and allergic manifestations. Although specific probiotic strains were used in these studies, their protective effects on allergic responses also might be common for all lactobacilli...
September 2016: Immunity, Inflammation and Disease
https://www.readbyqxmd.com/read/27602409/extreme-dysbiosis-of-the-microbiome-in-critical-illness
#15
Daniel McDonald, Gail Ackermann, Ludmila Khailova, Christine Baird, Daren Heyland, Rosemary Kozar, Margot Lemieux, Karrie Derenski, Judy King, Christine Vis-Kampen, Rob Knight, Paul E Wischmeyer
Critical illness is hypothesized to associate with loss of "health-promoting" commensal microbes and overgrowth of pathogenic bacteria (dysbiosis). This dysbiosis is believed to increase susceptibility to nosocomial infections, sepsis, and organ failure. A trial with prospective monitoring of the intensive care unit (ICU) patient microbiome using culture-independent techniques to confirm and characterize this dysbiosis is thus urgently needed. Characterizing ICU patient microbiome changes may provide first steps toward the development of diagnostic and therapeutic interventions using microbiome signatures...
July 2016: MSphere
https://www.readbyqxmd.com/read/27592384/the-gut-microbiota-a-treasure-for-human-health
#16
Daotong Li, Pan Wang, Pengpu Wang, Xiaosong Hu, Fang Chen
The interplay between the host and host-associated gut microbiota is an area of increasing interest during the recent decade. From young infants to elderly people, from primitive tribes to modern societies, accumulating evidence has suggested the association of critical physiological roles of gut microbiota in the pathogenesis of a variety of human metabolic, immunological and neurological diseases. Importantly, it appears that the relationship between the gut microbiota and disease is bidirectional, instead of causal or consequential...
November 15, 2016: Biotechnology Advances
https://www.readbyqxmd.com/read/27547201/a-critical-evaluation-of-bifidobacterial-adhesion-to-the-host-tissue
#17
REVIEW
Christina Westermann, Marita Gleinser, Sinéad C Corr, Christian U Riedel
Bifidobacteria are common inhabitants of the human gastrointestinal tract that, despite a long history of research, have not shown any pathogenic potential whatsoever. By contrast, some bifidobacteria are associated with a number of health-related benefits for the host. The reported beneficial effects of bifidobacteria include competitive exclusion of pathogens, alleviation of symptoms of irritable bowel syndrome and inflammatory bowel disease, and modulation of intestinal and systemic immune responses. Based on these effects, bifidobacteria are widely used as probiotics by pharmaceutical and dairy industries...
2016: Frontiers in Microbiology
https://www.readbyqxmd.com/read/27478897/infantile-colic-is-associated-with-low-grade-systemic-inflammation
#18
Anna Pärtty, Marko Kalliomäki, Seppo Salminen, Erika Isolauri
OBJECTIVE: Dysbiosis, an imbalance in the taxonomic composition of the gut bacteria occurring during the critical stages of development, induces lasting shifts in the immunological and metabolic phenotype if accompanied by an inflammatory response. As altered gut microbiota and successful treatment with probiotics have both been demonstrated in cases of colic, we hypothesized here that infants with colic might have low-grade inflammation. METHODS: In 28 infants with colic and in 12 healthy controls at the age of one month, we measured the following serum immunological biomarkers: cytokines interleukin 1β (IL-1β); IL-6; IL-10; tumor necrosis factor α (TNF-α); interferon γ (IFN-γ); chemokines IL-8; monocyte chemotactic protein-1 (MCP-1); macrophage inflammatory protein1β (MIP-1β) and chemokine (C-X-C motif) ligand 16 (CXCL16); intestinal-fatty-acid-binding protein (ifabp), a biomarker of enterocyte damage and zonulin, a biomarker of intestinal permeability...
July 14, 2016: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/27452748/-maintenance-of-intestinal-barrier-function-in-patients-with-chronic-critical-illness
#19
Xiuwen Wu, Jianan Ren, Jieshou Li
The syndrome known as chronic critical illness (CCI) is defined as that critically ill patients survive their initial acute illness but go on to experience persistent organ failures necessitating prolonged intensive care. Intestinal barrier is the physical barrier that separates the internal and external environments and prevents the invasion of pathogenic antigens. Due to its pathogenesis, many CCI patients have injured intestinal barrier. Gut is the motor organ of stress responses, and gut-associated infections may initiate multiple organ dysfunction...
July 2016: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/27380597/early-microbe-contact-and-obesity-risk-evidence-of-causality
#20
Erika Isolauri, Seppo Salminen, Samuli Rautava
The industrialized societies worldwide are in the middle of epidemics of diet-related chronic diseases, obesity being the common denominator. Lately, these conditions have been linked with a distinct microbiota composition in affected individuals different from that of healthy individuals. In particular, dysbiosis during critical stages of development induces lasting alterations in the immune and metabolic phenotype. The compositional development of the gut microbiota, again, is highly sensitive to environmental influences such as maternal health and nutrition, the mode of delivery, early feeding and antibiotic use...
July 2016: Journal of Pediatric Gastroenterology and Nutrition
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