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https://www.readbyqxmd.com/read/29141967/yogurt-and-cardiometabolic-diseases-a-critical-review-of-potential-mechanisms
#1
REVIEW
Melissa Anne Fernandez, Shirin Panahi, Noémie Daniel, Angelo Tremblay, André Marette
Associations between yogurt intake and risk of diet-related cardiometabolic diseases (CMDs) have been the subject of recent research in epidemiologic nutrition. A healthy dietary pattern has been identified as a pillar for the prevention of weight gain and CMDs. Epidemiologic studies suggest that yogurt consumption is linked to healthy dietary patterns, lifestyles, and reduced risk of CMDs, particularly type 2 diabetes. However, to our knowledge, few to no randomized controlled trials have investigated yogurt intake in relation to cardiometabolic clinical outcomes...
November 2017: Advances in Nutrition
https://www.readbyqxmd.com/read/29132794/saccharomyces-cerevisiae-fungemia-after-probiotic-treatment-in-an-intensive-care-unit-patient
#2
I Kara, F Yıldırım, Ö Özgen, S Erganiş, M Aydoğdu, M Dizbay, G Gürsel, A Kalkanci
Saccharomyces cerevisiae is a common colonizer of the human gastrointestinal system as a benign organism. Enteral supplementation of this yeast as a probiotic product is effective in the treatment of antibiotic associated diarrhae. In rare occasions it can cause invasive infections. We present two fungemia cases in an intensive care unit following probiotic treatment containing S. boulardii. We are warning the safety of probiotic treatment in critically ill patients.
November 10, 2017: Journal de Mycologie Médicale
https://www.readbyqxmd.com/read/29132736/clinical-effects-of-probiotics-in-cystic-fibrosis-patients-a-systematic-review
#3
Stephanie Van Biervliet, Dimitri Declercq, Shawn Somerset
Cystic fibrosis (CF) is characterised by a build-up of thick, intransient mucus linings of the digestive and respiratory mucosa, which disrupts digestive system functioning and microbiota composition. In view of the potential for probiotics to enhance microbiota composition in other contexts, this study investigated the current evidence for probiotics as an adjunct to usual therapy for CF. Electronic clinical databases were interrogated for human randomised, controlled, intervention trials (1985-2015) testing the effects of probiotics on clinical endpoints in CF were reviewed...
April 2017: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/29120368/lactobacillus-bulgaricus-lactobacillus-rhamnosus-and-lactobacillus-paracasei-attenuate-salmonella-enteritidis-salmonella-heidelberg-and-salmonella-typhimurium-colonization-and-virulence-gene-expression-in-vitro
#4
Muhammed Shafeekh Muyyarikkandy, Mary Anne Amalaradjou
Salmonella Enteritidis (SE), Salmonella Typhimurium (ST), and Salmonella Heidelberg (SH) have been responsible for numerous outbreaks associated with the consumption of poultry meat and eggs. Salmonella colonization in chicken is characterized by initial attachment to the cecal epithelial cells (CEC) followed by dissemination to the liver, spleen, and oviduct. Since cecal colonization is critical to Salmonella transmission along the food chain continuum, reducing this intestinal association could potentially decrease poultry meat and egg contamination...
November 9, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29064056/isolation-identification-of-lactobacillus-mucosae-an1-and-its-antilisterial-peptide-purification-and-characterization
#5
Ayyanna Repally, Venkatesh Perumal, Ankaiah Dasari, Esakkiraj Palanichamy, Arul Venkatesan
Lactobacillus mucosae strain AN1 isolated from sheep milk and characterized for its probiotic suitability. In vitro evaluation of critical gut endurance properties of this strain were assessed by different screening methods such as bile salt, gastric acid, lysozyme tolerance assays, hemolytic, cholesterol reduction properties, and HT-29 cell line adhesion assay. Antibacterial peptide from this strain was purified using ammonium sulphate precipitation, gel filtration chromatography and reverse-phase HPLC. The molecular mass of peptides was determined by Tricine-SDS-PAGE and confirmed by matrix-assisted laser desorption ionization-time of flight mass spectroscopy (MALDI-TOF-MS)...
October 24, 2017: Probiotics and Antimicrobial Proteins
https://www.readbyqxmd.com/read/29035308/gut-microbiota-and-nonalcoholic-fatty-liver-disease-insights-on-mechanisms-and-therapy
#6
REVIEW
Junli Ma, Qihang Zhou, Houkai Li
The gut microbiota plays critical roles in development of obese-related metabolic diseases such as nonalcoholic fatty liver disease (NAFLD), type 2 diabetes(T2D), and insulin resistance(IR), highlighting the potential of gut microbiota-targeted therapies in these diseases. There are various ways that gut microbiota can be manipulated, including through use of probiotics, prebiotics, synbiotics, antibiotics, and some active components from herbal medicines. In this review, we review the main roles of gut microbiota in mediating the development of NAFLD, and the advances in gut microbiota-targeted therapies for NAFLD in both the experimental and clinical studies, as well as the conclusions on the prospect of gut microbiota-targeted therapies in the future...
October 16, 2017: Nutrients
https://www.readbyqxmd.com/read/28983453/remote-sensing-between-liver-and-intestine-importance-of-microbial-metabolites
#7
Zidong Donna Fu, Julia Yue Cui
Recent technological advancements including metagenomics sequencing and metabolomics have allowed the discovery of critical functions of gut microbiota in obesity, malnutrition, neurological disorders, asthma, and xenobiotic metabolism. Classification of the human gut microbiome into distinct "enterotypes" has been proposed to serve as a new paradigm for understanding the interplay between microbial variation and human disease phenotypes, as many organs are affected by gut microbiota modifications during the pathogenesis of diseases...
June 2017: Current Pharmacology Reports
https://www.readbyqxmd.com/read/28983411/intestinal-microbiota-a-potential-target-for-the-treatment-of-postmenopausal-osteoporosis
#8
REVIEW
Xin Xu, Xiaoyue Jia, Longyi Mo, Chengcheng Liu, Liwei Zheng, Quan Yuan, Xuedong Zhou
Postmenopausal osteoporosis (PMO) is a prevalent metabolic bone disease characterized by bone loss and structural destruction, which increases the risk of fracture in postmenopausal women. Owing to the high morbidity and serious complications of PMO, many efforts have been devoted to its prophylaxis and treatment. The intestinal microbiota is the complex community of microorganisms colonizing the gastrointestinal tract. Probiotics, which are dietary or medical supplements consisting of beneficial intestinal bacteria, work in concert with endogenous intestinal microorganisms to maintain host health...
2017: Bone Research
https://www.readbyqxmd.com/read/28979247/probiotic-mixture-golden-bifido-prevents-neonatal-escherichia-coli-k1-translocation-via-enhancing-intestinal-defense
#9
Qing Zeng, Xiaolong He, Santhosh Puthiyakunnon, Hansen Xiao, Zelong Gong, Swapna Boddu, Lecheng Chen, Huiwen Tian, Sheng-He Huang, Hong Cao
Escherichia coli (E. coli) K1 sepsis and meningitis is a severe infection characterized by high mortality in neonates. Successful colonization and translocation across the intestinal mucosa have been regarded as the critical steps for E. coli K1 sepsis and meningitis. We recently reported that the probiotic mixture, Golden Bifido (containing live Lactobacillus bulgaricus, Bifidobacterium, and Streptococcus thermophilus, LBS) has a preventive role against neonatal E. coli K1 bacteremia and meningitis. However, the interaction between the neonatal gut barrier, probiotics and E...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28946645/safety-assessment-of-lactobacillus-helveticus-klds1-8701-based-on-whole-genome-sequencing-and-oral-toxicity-studies
#10
Bailiang Li, Da Jin, Smith Etareri Evivie, Na Li, Fenfen Yan, Li Zhao, Fei Liu, Guicheng Huo
Lactobacillus helveticus KLDS1.8701 isolated from Chinese traditional fermented dairy product has been shown earlier to possess probiotic potentials but it is important to evaluate its safety in view of its possible use as a probiotic. The aim of the present study is to critically assess the safety of L. helveticus KLDS1.8701 through multiple perspectives. The complete genome of L. helveticus KLDS1.8701 was sequenced to mine for safety-associated genes. The minimum inhibitory concentrations of 15 antimicrobials and the adverse metabolites were determined...
September 24, 2017: Toxins
https://www.readbyqxmd.com/read/28931041/lactobacillus-paracasei-feeding-improves-immune-control-of-influenza-infection-in-mice
#11
Nouria Belkacem, Nicolas Serafini, Richard Wheeler, Muriel Derrien, Lilia Boucinha, Aurélie Couesnon, Nadine Cerf-Bensussan, Ivo Gomperts Boneca, James P Di Santo, Muhamed-Kkeir Taha, Raphaëlle Bourdet-Sicard
Respiratory tract infections such as flu cause severe morbidity and mortality and are among the leading causes of death in children and adults worldwide. Commensal microbiota is critical for orchestrating tissue homeostasis and immunity in the intestine. Probiotics represent an interesting source of immune modulators and several clinical studies have addressed the potential beneficial effects of probiotics against respiratory infections. Therefore, we have investigated the mechanisms of protection conferred by L...
2017: PloS One
https://www.readbyqxmd.com/read/28914249/visual-pedagogy-and-probiotics-for-hearing-impaired-children-a-pilot-study
#12
Amrita Sujlana, Ruchika Goyal, Parampreet Pannu, Shireen Opal, Palki Bansal
CONTEXT: Oral health care for children with special needs remains largely unmet. It is important that we should focus on preventive strategies for special children to help curtail and prevent oral diseases. AIM: This study aimed to assess the effect of visual pedagogy and probiotic mouth rinse on the periodontal health of hearing impaired children. MATERIALS AND METHODOLOGY: The study cohort consisted of twenty children with hearing impairment (HI) and 20 age-matched healthy children...
October 2017: Journal of the Indian Society of Pedodontics and Preventive Dentistry
https://www.readbyqxmd.com/read/28867947/lactobacillus-casei-encapsulated-in-soy-protein-isolate-and-alginate-microparticles-prepared-by-spray-drying
#13
Jasmina Hadzieva, Kristina Mladenovska, Maja Simonoska Crcarevska, Marija Glavaš Dodov, Simona Dimchevska, Nikola Geškovski, Anita Grozdanov, Emil Popovski, Gjorgji Petruševski, Marina Chachorovska, Tanja Petreska Ivanovska, Lidija Petruševska-Tozi, Sonja Ugarkovic, Katerina Goracinova
This article presents a novel formulation for preparation of Lactobacillus casei 01 encapsulated in soy protein isolate and alginate microparticles using spray drying method. A response surface methodology was used to optimise the formulation and the central composite face-centered design was applied to study the effects of critical material attributes and process parameters on viability of the probiotic after microencapsulation and in simulated gastrointestinal conditions. Spherical microparticles were produced in high yield (64%), narrow size distribution (d50=9...
June 2017: Food Technology and Biotechnology
https://www.readbyqxmd.com/read/28865967/bugging-allergy-role-of-pre-pro-and-synbiotics-in-allergy-prevention
#14
REVIEW
Christina E West, Majda Dzidic, Susan L Prescott, Maria C Jenmalm
Large-scale biodiversity loss and complex changes in social behaviors are altering human microbial ecology. This is increasingly implicated in the global rise in inflammatory diseases, most notably the "allergy epidemic" in very early life. Colonization of human ecological niches, particularly the gastrointestinal tract, is critical for normal local and systemic immune development and regulation. Disturbances in composition, diversity and timing of microbial colonization have been associated with increased allergy risk, indicating the importance of strategies to restore a dysbiotic gut microbiota in the primary prevention of allergic diseases, including the administration of probiotics, prebiotics and synbiotics...
October 2017: Allergology International: Official Journal of the Japanese Society of Allergology
https://www.readbyqxmd.com/read/28837361/role-of-honey-in-topical-and-systemic-bacterial-infections
#15
Muhammad Barkaat Hussain
BACKGROUND: The development of bacterial resistance to antibiotics has made it more difficult and expensive to treat infections. Honey is getting worldwide attention as a topical therapeutic agent for wound infections and potential future candidate for systemic infections. OBJECTIVES: The purpose of this review was to summarise different antibacterial bio-active compounds in honey, their synergistic interaction and their clinical implications in topical and systemic infections...
August 24, 2017: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/28783552/a-meta-analysis-of-randomized-trials-assessing-the-effects-of-probiotic-preparations-on-oral-candidiasis-in-the-elderly
#16
REVIEW
Ruixue Ai, Jiao Wei, Danhua Ma, Lu Jiang, Hongxia Dan, Yu Zhou, Ning Ji, Xin Zeng, Qianming Chen
OBJECTIVE: Oral candidiasis is the most common fungal infection and can be attributed in part to dysbiosis, an imbalance in the resident oral microflora. Therefore, probiotics, which counter pathogenic microorganisms through competitive, antagonistic, and immunological effects, have been used by some clinicians. To date, the effect of probiotics in preventing oral candidiasis in the elderly is controversial. A systematic review that summarizes and critically appraises the available clinical trials is therefore necessary...
April 30, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/28776643/contributions-of-the-intestinal-microbiome-in-lung-immunity
#17
REVIEW
Jeremy P McAleer, Jay K Kolls
The intestine is a critical site of immune cell development that not only controls intestinal immunity but extra-intestinal immunity as well. Recent findings have highlighted important roles for gut microbiota in shaping lung inflammation. Here, we discuss interactions between the microbiota and immune system including T cells, protective effects of microbiota on lung infections, the role of diet in shaping the composition of gut microbiota and susceptibility to asthma, epidemiologic evidence implicating antibiotic use and microbiota in asthma and clinical trials investigating probiotics as potential treatments for atopy and asthma...
August 4, 2017: European Journal of Immunology
https://www.readbyqxmd.com/read/28769917/identification-and-functional-validation-of-autolysis-associated-genes-in-lactobacillus-bulgaricus-atcc-baa-365
#18
Xiaoyang Pang, Shuwen Zhang, Jing Lu, Lu Liu, Changlu Ma, Yang Yang, Panpan Ti, Weihua Gao, Jiaping Lv
Lactic acid bacteria (LAB) are important organisms in food production. Indeed, LAB autolysis is very critical in dairy processing. For example, it influences the development of cheese flavor by releasing intracellular enzymes, and controls cell growth in yogurts and probiotic products. Two component systems (TCS) constitute essential environmental sensors and effectors of signal transduction in most bacteria. In the present work, mutants of one TCS (LBUL_RS00115/LBUL_RS00110) were generated to assess the relationship between TCS and cell autolysis...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28760934/next-generation-probiotics-targeting-clostridium-difficile-through-precursor-directed-antimicrobial-biosynthesis
#19
Jennifer K Spinler, Jennifer Auchtung, Aaron Brown, Prapaporn Boonma, Numan Oezguen, Caná L Ross, Ruth Ann Luna, Jessica Runge, James Versalovic, Alex Peniche, Sara M Dann, Robert A Britton, Anthony Haag, Tor C Savidge
Integration of antibiotic and probiotic therapy has the potential to lessen the public health burden of antimicrobial-associated diseases. Clostridium difficile infection (CDI) represents an important example where the rational design of next-generation probiotics is being actively pursued to prevent disease recurrence. Because intrinsic resistance to clinically relevant antibiotics used to treat CDI (vancomycin, metronidazole, and fidaxomicin) is a desired trait in such probiotic species, we screened several bacteria and identified Lactobacillus reuteri to be a promising candidate for adjunct therapy...
October 2017: Infection and Immunity
https://www.readbyqxmd.com/read/28758582/potential-novel-treatments-for-bipolar-depression-ketamine-fatty-acids-anti-inflammatory-agents-and-probiotics
#20
G H Vázquez, S Camino, L Tondo, Ross J Baldessarini
BACKGROUND: Treatments for depression in bipolar disorder (BD) are far less well developed than for unipolar major depressive disorder. Several innovative and experimental approaches have been emerging recently, including use of the dissociative anesthetic ketamine and other antagonists of central NMDA glutamate receptors, as well as unsaturated fatty acids, anti-inflammatory agents, and possibly probiotic methods. METHODS: We reviewed relevant reports from the past decade...
July 28, 2017: CNS & Neurological Disorders Drug Targets
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