keyword
MENU ▼
Read by QxMD icon Read
search

Open access

keyword
https://www.readbyqxmd.com/read/29166698/-the-value-of-endoscopic-decompression-in-surgical-therapy-of-carpal-tunnel-syndrome
#1
Maximilian E T Hessenauer, Andreas Arkudas, Ingo Ludoph, Elias Polykandriotis, Raymund E Horch
Carpal tunnel syndrome is one of the most common diseases in hand surgery. The gold standard in therapy is the surgical release of the carpal tunnel. We provide a brief update on the relevant pathogenesis, diagnosis and therapy and discuss questions related to minimal invasive decompression of the median nerve. Together with a review of the current literature, we report on our experiences in minimally invasive carpal tunnel release via a monoportal endoscopic access in over 700 cases. In conclusion, the endoscopic technique provides superior convalescence and patient safety is comparable to open methods...
November 22, 2017: Zentralblatt Für Chirurgie
https://www.readbyqxmd.com/read/29166336/valganciclovir-prophylaxis-versus-preemptive-therapy-in-cytomegalovirus-positive-renal-allograft-recipients-long-term-results-after-7-years-of-a-randomized-clinical-trial
#2
Oliver Witzke, Martin Nitschke, Michael Bartels, Heiner Wolters, Gunter Wolf, Petra Reinke, Ingeborg A Hauser, Ulrich Alshuth, Volker Kliem
BACKGROUND: The VIPP study compared valganciclovir prophylaxis with preemptive treatment regarding efficacy, safety and long-term graft outcome in CMV-positive (R+) renal transplant recipients. METHODS: Multicenter, open-label, randomized clinical study with a 12-month study phase and a follow-up of up to 84 months. Patients in the prophylaxis group received 2x450 mg/day oral valganciclovir for 100 days adjusted to renal function. Preemptive treatment with 2x900 mg/day valganciclovir was initiated at a viral load of ≥400 CMV copies/mL (PCR) and maintained over ≥14 days, followed by secondary prophylaxis...
November 22, 2017: Transplantation
https://www.readbyqxmd.com/read/29166331/223ra-therapy-in-patients-with-advanced-castration-resistant-prostate-cancer-with-bone-metastases-lessons-from-daily-practice
#3
Maarten J van der Doelen, Malou C P Kuppen, Marianne A Jonker, Niven Mehra, Marcel J R Janssen, Inge M van Oort, Winald R Gerritsen
PURPOSE: To identify pre-therapeutic variables associated with overall survival (OS) in patients treated with Ra. METHODS: Data from 45 CRPC patients treated with Ra were retrospectively analyzed. All patients who received at least one Ra injection were included in the study. Cox proportional hazard regression models were used to estimate hazard ratio's (HR) and to test for association. RESULTS: Twenty-one patients (47%) received six Ra injections and 24 patients (53%) received one to five Ra injections...
November 22, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/29166297/assessing-patients-perceptions-of-safety-culture-in-the-hospital-setting-development-and-initial-evaluation-of-the-patients-perceptions-of-safety-culture-scale
#4
Clara Monaca, Beate Bestmann, Martina Kattein, Daria Langner, Hardy Müller, Tanja Manser
OBJECTIVES: Both, patient satisfaction and hospital safety culture have been recognized as key characteristics of healthcare quality and patient safety. Thus, both characteristics are measured widely to support quality and safety improvement efforts. However, because safety culture surveys focus exclusively on the perspective of hospital staff, the complimentary information to be gained from patients' perceptions of safety culture has received little research attention so far. We aimed to develop a measure explicitly focusing on patients' perceptions of safety culture in the hospital setting and perform an initial evaluation of its measurement properties...
November 21, 2017: Journal of Patient Safety
https://www.readbyqxmd.com/read/29166045/controlling-relative-polymorph-stability-in-soft-porous-crystals-with-a-barostat
#5
Nathan A Mahynski, Vincent K Shen
We use Monte Carlo simulations to investigate the thermodynamic behavior of soft porous crystal (SPC) adsorbents under the influence of an external barostat. We consider SPCs that naturally exhibit polymorphism between crystal forms of two distinct pore sizes. In the absence of barostatting, these crystals may be naturally divided into two categories depending on their response to stress applied by the adsorbate fluid: those which macroscopically deform and change the volume of their unit cell ("breathing") and those which instead undergo internal rearrangements that change the adsorbate-accessible volume without modifying the unit cell volume ("gate-opening")...
June 14, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/29165655/expression-atlas-gene-and-protein-expression-across-multiple-studies-and-organisms
#6
Irene Papatheodorou, Nuno A Fonseca, Maria Keays, Y Amy Tang, Elisabet Barrera, Wojciech Bazant, Melissa Burke, Anja Füllgrabe, Alfonso Muñoz-Pomer Fuentes, Nancy George, Laura Huerta, Satu Koskinen, Suhaib Mohammed, Matthew Geniza, Justin Preece, Pankaj Jaiswal, Andrew F Jarnuczak, Wolfgang Huber, Oliver Stegle, Juan Antonio Vizcaino, Alvis Brazma, Robert Petryszak
Expression Atlas (http://www.ebi.ac.uk/gxa) is an added value database that provides information about gene and protein expression in different species and contexts, such as tissue, developmental stage, disease or cell type. The available public and controlled access data sets from different sources are curated and re-analysed using standardized, open source pipelines and made available for queries, download and visualization. As of August 2017, Expression Atlas holds data from 3,126 studies across 33 different species, including 731 from plants...
November 20, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/29164890/divergent-access-to-functionalized-pyrrolidines-and-pyrrolines-via-iridium-catalyzed-domino-ring-opening-cyclization-of-vinyl-aziridines-with-%C3%AE-ketocarbonyls
#7
Tao-Yan Lin, Hai-Hong Wu, Jian-Jun Feng, Junliang Zhang
A useful synthesis of five-membered N-heterocycles has been developed through an iridium-catalyzed domino-ring-opening cyclization of vinylaziridines with β-ketocarbonyls. α-Substituted 1,3-dicarbonyls reacted with vinylaziridines to give 2-methylenepyrrolidines bearing two adjacent sp(3)-carbon centers with moderate to excellent diastereoselectivity, while the reaction of α-unsubstituted 1,3-dicarbonyls afforded 2-pyrrolines in good yield.
November 22, 2017: Organic Letters
https://www.readbyqxmd.com/read/29164756/survey-of-disability-related-content-in-australian-dietetics-programs
#8
Shannon Butler, Jane Kellett, Rachel Bacon, Annette Byron
AIM: Nutrition and dietetic services are an important component of healthcare for people living with a disability. The introduction of the National Disability Insurance Scheme (NDIS) in Australia is providing more opportunities for individuals to access these services from an Accredited Practising Dietitian (APD). The aim of this research was to identify how students in Australian tertiary dietetics programs are being prepared to provide these services to people with a disability. METHODS: A purpose-built questionnaire with eight open-ended questions was developed by the researchers to describe the disability-related content of university and professional placement learning opportunities and was distributed to all course conveners (or their nominated representative) of dietetics programs accredited by the Dietitians Association of Australia...
November 21, 2017: Nutrition & Dietetics: the Journal of the Dietitians Association of Australia
https://www.readbyqxmd.com/read/29164743/patient-initiated-recruitment-for-clinical-research-evaluation-of-an-outpatient-letter-research-statement
#9
Matthias Wienroth, Louise Caffrey, Charles Wolfe, Christopher McKevitt
BACKGROUND: UK Hospital Trusts are charged with increasing patients' research awareness and willingness to take part in research. This includes implementing strategies to encourage patient-initiated enquiries about participation. OBJECTIVES: To evaluate the impact of a research statement inserted in outpatient letters in one clinical service, and to derive suggestions on potential steps towards increasing patient-initiated recruitment. SETTING: A medical outpatient clinic of a research-active hospital trust, serving an inner-city multi-ethnic population across two boroughs...
November 22, 2017: Health Expectations: An International Journal of Public Participation in Health Care and Health Policy
https://www.readbyqxmd.com/read/29164388/correction-to-physiological-insights-of-recent-clinical-diagnostic-and-therapeutic-technologies-for-cardiovascular-diseases
#10
Kenji Shigemi, Soichiro Fuke, Dai Une, Keita Saku, Shuji Shimizu, Toru Kawada, Toshiaki Shishido, Kenji Sunagawa, Masaru Sugimachi
The article Physiological insights of recent clinical diagnostic and therapeutic technologies for cardiovascular diseases, written by Kenji Shigemi, Soichiro Fuke, Dai Une, Keita Saku, Shuji Shimizu, Toru Kawada, Toshiaki Shishido, Kenji Sunagawa and Masaru Sugimachi, was originally published Online First without open access.
November 21, 2017: Journal of Physiological Sciences: JPS
https://www.readbyqxmd.com/read/29164190/upgrading-well-plates-using-open-microfluidic-patterning
#11
Samuel B Berry, Tianzi Zhang, John H Day, Xiaojing Su, Ilham Z Wilson, Erwin Berthier, Ashleigh B Theberge
Cellular communication between multiple cell types is a ubiquitous process that is responsible for vital physiological responses observed in vivo (e.g., immune response, organ function). Many in vitro coculture strategies have been developed, both in traditional culture and microscale systems, and have shown the potential to recreate some of the physiological behaviors of organs or groups of cells. A fundamental limitation of current systems is the difficulty of reconciling the additional engineering requirements for creating soluble factor signaling systems (e...
November 22, 2017: Lab on a Chip
https://www.readbyqxmd.com/read/29163985/response-to-inhaled-loxapine-in-patients-with-schizophrenia-or-bipolar-i-disorder-panss-ec-responder-analyses
#12
Scott Zeller, Leslie Zun, James V Cassella, Daniel A Spyker, Paul P Yeung
Background: Efficacy of inhaled loxapine 5 or 10 mg in treating agitation was shown using the Positive and Negative Syndrome Scale - Excited Component (PANSS-EC) in two Phase III randomised, double-blind, placebo-controlled trials in 344 agitated patients with schizophrenia and 314 patients with bipolar I disorder (Clinicaltrials.gov: NCT00628589, NCT00721955). Aims: To examine the five individual items comprising the PANSS-EC and the percentage of patients achieving a clinical response (reduction of ≥40%) in PANSS-EC (Response-40) for these two studies...
November 2017: BJPsych Open
https://www.readbyqxmd.com/read/29163984/retrospective-cohort-follow-up-study-of-individuals-detained-under-section-136
#13
Jennifer L Burgess, Sarah-Jane White, Aileen O'Brien
Background: An original cohort study found that over half of the individuals detained under Section 136 (S136) of the Mental Health Act 1983 were discharged home after assessment, and nearly half were intoxicated. Aims: To investigate whether the cohort was followed up by psychiatric services, characterise those repeatedly detained and assess whether substance use was related to these outcomes. Method: Data were retrospectively collected from the notes of 242 individuals, who presented after S136 detention to a place of safety over a 6-month period, and were followed up for 1 year...
November 2017: BJPsych Open
https://www.readbyqxmd.com/read/29163983/cognitive-ability-and-risk-of-post-traumatic-stress-disorder-after-military-deployment-an-observational-cohort-study
#14
Lars R Nissen, Karen-Inge Karstoft, Mia S Vedtofte, Anni B S Nielsen, Merete Osler, Erik L Mortensen, Gunhild T Christensen, Søren B Andersen
Background: Studies of the association between pre-deployment cognitive ability and post-deployment post-traumatic stress disorder (PTSD) have shown mixed results. Aims: To study the influence of pre-deployment cognitive ability on PTSD symptoms 6-8 months post-deployment in a large population while controlling for pre-deployment education and deployment-related variables. Method: Study linking prospective pre-deployment conscription board data with post-deployment self-reported data in 9695 Danish Army personnel deployed to different war zones in 1997-2013...
November 2017: BJPsych Open
https://www.readbyqxmd.com/read/29163982/individual-differences-in-schizophrenia
#15
Edmund T Rolls, Wenlian Lu, Lin Wan, Hao Yan, Chuanyue Wang, Fude Yang, Yunlong Tan, Lingjiang Li, Hao Yu, Peter F Liddle, Lena Palaniyappan, Dai Zhang, Weihua Yue, Jianfeng Feng
Background: Whether there are distinct subtypes of schizophrenia is an important issue to advance understanding and treatment of schizophrenia. Aims: To understand and treat individuals with schizophrenia, the aim was to advance understanding of differences between individuals, whether there are discrete subtypes, and how first-episode patients (FEP) may differ from multiple episode patients (MEP). Method: These issues were analysed in 687 FEP and 1880 MEP with schizophrenia using the Positive and Negative Syndrome Scale for (PANSS) schizophrenia before and after antipsychotic medication for 6 weeks...
November 2017: BJPsych Open
https://www.readbyqxmd.com/read/29163915/field-deployable-quantitative-rapid-identification-of-active-ebola-virus-infection-in-unprocessed-blood
#16
Kavit Shah, Emma Bentley, Adam Tyler, Kevin S R Richards, Edward Wright, Linda Easterbrook, Diane Lee, Claire Cleaver, Louise Usher, Jane E Burton, James K Pitman, Christine B Bruce, David Edge, Martin Lee, Nelson Nazareth, David A Norwood, Sterghios A Moschos
The West African Ebola virus outbreak underlined the importance of delivering mass diagnostic capability outside the clinical or primary care setting in effectively containing public health emergencies caused by infectious disease. Yet, to date, there is no solution for reliably deploying at the point of need the gold standard diagnostic method, real time quantitative reverse transcription polymerase chain reaction (RT-qPCR), in a laboratory infrastructure-free manner. In this proof of principle work, we demonstrate direct performance of RT-qPCR on fresh blood using far-red fluorophores to resolve fluorogenic signal inhibition and controlled, rapid freeze/thawing to achieve viral genome extraction in a single reaction chamber assay...
November 1, 2017: Chemical Science
https://www.readbyqxmd.com/read/29163747/endovascular-stenting-of-tandem-carotid-artery-origin-and-bifurcation-stenotic-lesions-using-flow-reversal
#17
Andrew A Fanous, Parham Yashar, Ashish Sonig, Amanda Zakeri, Kenneth V Snyder, Elad I Levy, Jason M Davies, Adnan H Siddiqui
Background: The treatment of tandem lesions involving severe stenosis of the internal carotid artery with concomitant stenosis of the ipsilateral common carotid artery (CCA) origin represents an ongoing challenge. Current options for the treatment of tandem carotid artery origin and bifurcation stenotic lesions include open surgical endarterectomy, endovascular stenting, balloon angioplasty, and hybrid procedures combining both modalities. However, these options are either associated with high peri-operative risks or not always anatomically feasible...
October 2017: Journal of Vascular and Interventional Neurology
https://www.readbyqxmd.com/read/29162096/carer-involvement-in-compulsory-out-patient-psychiatric-care-in-england
#18
Jorun Rugkåsa, Krysia Canvin
BACKGROUND: There is an expectation in current heath care policy that family carers are involved in service delivery. This is also the case with compulsory outpatient mental health care, Community Treatment Orders (CTOs) that were introduced in England in 2008. No study has systematically investigated family involvement through the CTO process. METHOD: We conducted qualitative interviews with 24 family carers to ascertain their views and experiences of involvement in CTOs...
November 21, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/29161433/jaspar-2018-update-of-the-open-access-database-of-transcription-factor-binding-profiles-and-its-web-framework
#19
Aziz Khan, Oriol Fornes, Arnaud Stigliani, Marius Gheorghe, Jaime A Castro-Mondragon, Robin van der Lee, Adrien Bessy, Jeanne Chèneby, Shubhada R Kulkarni, Ge Tan, Damir Baranasic, David J Arenillas, Albin Sandelin, Klaas Vandepoele, Boris Lenhard, Benoît Ballester, Wyeth W Wasserman, François Parcy, Anthony Mathelier
No abstract text is available yet for this article.
November 17, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/29161421/europe-pmc-in-2017
#20
Maria Levchenko, Yuci Gou, Florian Graef, Audrey Hamelers, Zhan Huang, Michele Ide-Smith, Anusha Iyer, Oliver Kilian, Jyothi Katuri, Jee-Hyub Kim, Nikos Marinos, Rakesh Nambiar, Michael Parkin, Xingjun Pi, Frances Rogers, Francesco Talo, Vid Vartak, Aravind Venkatesan, Johanna McEntyre
Europe PMC (https://europepmc.org) is a comprehensive resource of biomedical research publications that offers advanced tools for search, retrieval, and interaction with the scientific literature. This article outlines new developments since 2014. In addition to delivering the core database and services, Europe PMC focuses on three areas of development: individual user services, data integration, and infrastructure to support text and data mining. Europe PMC now provides user accounts to save search queries and claim publications to ORCIDs, as well as open access profiles for authors based on public ORCID records...
November 17, 2017: Nucleic Acids Research
keyword
keyword
40525
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"