keyword
MENU ▼
Read by QxMD icon Read
search

lycopene

keyword
https://www.readbyqxmd.com/read/28440717/serum-carotenoid-interactions-in-premenopausal-women-reveal-%C3%AE-carotene-is-negatively-impacted-by-body-fat
#1
Emily Taylor Nuss, Ashley R Valentine, Zhumin Zhang, HuiChuan Jennifer Lai, Sherry A Tanumihardjo
Increasing body mass indices (BMIs) across the globe reflect pandemic shifts towards habitual positive energy imbalances. Excess body fat in individuals is often associated with high-energy and high-fat diets scanty in fresh produce. Carotenoids are fat-soluble pigments plentiful in many fruits and vegetables. They are well-known for provitamin A and antioxidant functions, but little research has been done related to carotenoid-body mass interactions. Serum carotenoids were analyzed relative to body fat to determine correlations between major serum carotenoids, retinol, BMI, fat mass, and lean mass...
January 1, 2017: Experimental Biology and Medicine
https://www.readbyqxmd.com/read/28440398/lycopene-inhibits-nf-%C3%AE%C2%BAb-activation-and-adhesion-molecule-expression-through-nrf2-mediated-heme-oxygenase-1-in-endothelial-cells
#2
Po-Min Yang, Huang-Zhi Chen, Yu-Ting Huang, Chia-Wen Hsieh, Being-Sun Wung
The endothelial expression of cell adhesion molecules plays a leading role in atherosclerosis. Lycopene, a carotenoid with 11 conjugated double bonds, has been shown to have anti-inflammatory properties. In the present study, we demonstrate a putative mechanism for the anti-inflammatory effects of lycopene. We demonstrate that lycopene inhibits the adhesion of tumor necrosis factor α (TNFα)-stimulated monocytes to endothelial cells and suppresses the expression of intercellular cell adhesion molecule-1 (ICAM-1) at the transcriptional level...
April 20, 2017: International Journal of Molecular Medicine
https://www.readbyqxmd.com/read/28440323/increased-dietary-and-circulating-lycopene-are-associated-with-reduced-prostate-cancer-risk-a-systematic-review-and-meta-analysis
#3
REVIEW
J L Rowles, K M Ranard, J W Smith, R An, J W Erdman
BACKGROUND: Prostate cancer (PCa) is the fifth leading cause of cancer-related deaths worldwide. Many epidemiological studies have investigated the association between prostate cancer and lycopene, however, results have been inconsistent. This study aims to determine the impact of dietary and circulating concentrations of lycopene on PCa risk and to investigate potential dose-response associations. METHODS: We conducted a systematic review and dose-response meta-analysis for the for the association between dietary and circulating lycopene and PCa risk...
April 25, 2017: Prostate Cancer and Prostatic Diseases
https://www.readbyqxmd.com/read/28436684/serenoa-repens-for-lower-urinary-tract-symptoms-benign-prostatic-hyperplasia-current-evidence-and-its-clinical-implications-in-naturopathic-medicine
#4
Soo Liang Ooi, Sok Cheon Pak
OBJECTIVES: Benign prostatic hyperplasia (BPH) commonly affects men above 40 years old. The progression of BPH is often accompanied with lower urinary tract symptoms (LUTS) that can significantly affect the quality of life of the patients. Serenoa repens (saw palmetto) is a popular herbal remedy indicated for LUTS/BPH. We reviewed the current research on the efficacy of S. repens on LUTS/BPH as a monotherapy as well as combination therapies. DESIGN: Non-systematic searches were performed in PubMed for human studies and systematic reviews on the topic...
April 24, 2017: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/28421798/assessment-of-individual-carotenoid-and-vitamin-a-dietary-intake-in-overweight-and-obese-dominican-subjects
#5
Madeline Durán-Cabral, Irene Fernández-Jalao, Rocío Estévez-Santiago, Begoña Olmedilla Alonso
INTRODUCTION: Carotenoids are plant pigment with important biological activities in humans, such as provitamin-A among others. At present, there are no individual carotenoid intake data in the Dominican population, which is at risk of vitamin A deficiency and has an important percentage of overweight and obese individuals . OBJECTIVE: To assess the individual components of vitamin A intake (retinol, α-carotene, β-carotene and β-cryptoxanthin) and that of other relevant dietary carotenoids like lutein, zeaxanthin and lycopene of Dominican daily food intake...
March 30, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/28415774/chemoprevention-of-prostate-cancer-in-men-with-high-grade-prostatic-intraepithelial-neoplasia-hgpin-a-systematic-review-and-adjusted-indirect-treatment-comparison
#6
Kang Cui, Xiangnan Li, Yabing Du, Xiance Tang, Seiji Arai, Yiwei Geng, Ying Xi, Han Xu, Yue Zhou, Wang Ma, Tengfei Zhang
BACKGROUND: High-grade prostatic intraepithelial neoplasia (HGPIN) is the precursor or premalignant form of prostate cancer. At least 30% patients with a confirmed HGPIN will develop prostate cancer within 1 year after repeated biopsy. HGPIN patients are the appropriate at-risk population for chemoprevention strategies investigation against prostate cancer. However the commonly used chemoprevention agents that targeted on hormonal imbalance or lifestyle-related factors showed varied results in HGPIN patients...
March 15, 2017: Oncotarget
https://www.readbyqxmd.com/read/28415031/carotenoid-accumulation-in-durian-durio-zibethinus-fruit-is-affected-by-ethylene-via-modulation-of-carotenoid-pathway-gene-expression
#7
Apinya Wisutiamonkul, Charles Ampomah-Dwamena, Andrew C Allan, Saichol Ketsa
Carotenoid content in durian (Durio zibethinus) fruit is an important aspect of fruit quality, with different cultivars distinguished by differing pigmentation. We have studied the dependence of carotenogenesis on ethylene. Fruit of the cultivar 'Chanee' harvested at the mature stage were either left untreated (controls), treated with 1-methylcyclopropene (1-MCP) for 12 h, or treated with application of an aqueous ethephon solution to the stem end, or treated for 12 h with 1-MCP followed by ethephon application...
March 31, 2017: Plant Physiology and Biochemistry: PPB
https://www.readbyqxmd.com/read/28412198/potential-role-of-lycopene-in-targeting-proprotein-convertase-subtilisin-kexin-type-9-to-combat-hypercholesterolemia
#8
Sahir Sultan Alvi, Irfan A Ansari, Imran Khan, Johar Iqbal, M Salman Khan
Proprotein convertase subtilisin/kexin type 9 (PCSK-9) is a serine protease of the proprotien convertase (PC) family that has profound effects on plasma low density lipoprotein cholesterol (LDL-C) levels, the major risk factor for coronary heart disease (CHD), through its ability to mediate LDL receptor (LDL-R) protein degradation and reduced recycling to the surface of hepatocytes. Thus, the current study was premeditated not only to evaluate the role of lycopene in targeting the inhibition of PCSK-9 via modulation of genes involved in cholesterol homeostasis in HFD rats but also to examine a correlation between HFD induced inflammatory cascades and subsequent regulation of PCSK-9 expression...
April 12, 2017: Free Radical Biology & Medicine
https://www.readbyqxmd.com/read/28407181/in-vitro-effects-and-mechanisms-of-lycopene-in-mcf-7-human-breast-cancer-cells
#9
S J Peng, J Li, Y Zhou, M Tuo, X X Qin, Q Yu, H Cheng, Y M Li
Breast cancer adversely affects the health status of women; therefore, the prevention and treatment of breast cancer is of critical importance. Lycopene is known to possess several biological effects such as removal of free radicals, alleviation of biological oxidative injury, and inhibition of tumor growth. In this study, we aimed to illustrate the effect of lycopene on tumor cell proliferation and modulation of cancer progression as well as its possible underlying mechanisms in human breast carcinoma cell line MCF-7 in vitro...
April 13, 2017: Genetics and Molecular Research: GMR
https://www.readbyqxmd.com/read/28403343/lycopene-and-resveratrol-pretreatment-did-not-interfere-with-the-liver-of-hepatectomized-rats
#10
Pedro Paulo Barros, Gisele Mara Silva Gonçalves, Gustavo Henrique da Silva, Maria Clara Villaça Dias Bastos, Loren Nogaroto Ramos, Marilia Marinello Fernandes
Purpose: To investigate the effects of lycopene and resveratrol pretreatment on hepatic hyperplasia in partially hepatectomized rats. Methods: The lycopene group and the resveratrol group received 40 mg/kg/day of lycopene or resveratrol, respectively (dissolved in olive oil or in saline solution, respectively) and administered via a gastric tube for 30 days. The partially hepatectomzed (PH) control groups received saline or olive oil via a gastric tube for 30 days, respectively, and the normal control group received no treatment...
March 2017: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/28402743/generation-and-application-of-monoclonal-antibody-against-lycopene
#11
Valeriy V Tsibezov, Yuriy K Bashmakov, Dmitry V Pristenskiy, Naylia A Zigangirova, Ludmila V Kostina, Natalya E Chalyk, Alexey Y Kozlov, Elena Y Morgunova, Marina P Chernyshova, Marina V Lozbiakova, Nigel H Kyle, Ivan M Petyaev
A monoclonal antibody (Mab) against lycopene was developed from hybridoma clones obtained from BALB/c mice immunized with trans-isomer of lycopene (t-lycopene, t-LC) conjugated with colloidal gold particles. An alternating immunization schedule which included injection of both formulations of immunogen (without and with Freund's adjuvant) was most effective in the elucidation of a measurable immune response to the t-Lycopene conjugate. Selected hybridoma clones were able to produce an Mab positive in competition assay...
April 12, 2017: Monoclonal Antibodies in Immunodiagnosis and Immunotherapy
https://www.readbyqxmd.com/read/28402582/mechanical-and-structural-characterization-of-whey-protein-concentrate-montmorilonite-lycopene-films
#12
Rafaela C Pereira, João de Deus S Carneiro, Odílio B G Assis, Soraia V Borges
BACKGROUND: In the present study, the production and characterization of nanocomposites based on whey protein concentrate (WPC) and montmorilonite (MMT) incorporated of lycopene as functional substance is presented and discussed as an alternative biomaterial for potential use in foodstuff applications. A full factorial design with varying levels of MMT (0 and 20 g.Kg(-1) ) and lycopene (0, 60 and 120 g.Kg(-1) ) was used. Mechanical properties (tensile and puncture tests), thermal stability analysis, FT-IR vibrational spectroscopy and film morphology of the resulting materials were evaluated...
April 12, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28398228/quantification-of-lycopene-%C3%AE-carotene-and-total-soluble-solids-in-intact-red-flesh-watermelon-citrullus-lanatus-using-on-line-near-infrared-spectroscopy
#13
Elena Tamburini, Stefania Costa, Irene Rugiero, Paola Pedrini, Maria Gabriella Marchetti
A great interest has recently been focused on lycopene and β-carotene, because of their antioxidant action in the organism. Red-flesh watermelon is one of the main sources of lycopene as the most abundant carotenoid. The use of near-infrared spectroscopy (NIRS) in post-harvesting has permitted us to rapidly quantify lycopene, β-carotene, and total soluble solids (TSS) on single intact fruits. Watermelons, harvested in 2013-2015, were submitted to near-infrared (NIR) radiation while being transported along a conveyor belt system, stationary and in movement, and at different positions on the belt...
April 11, 2017: Sensors
https://www.readbyqxmd.com/read/28398223/cloning-and-functional-characterization-of-a-lycopene-%C3%AE-cyclase-from-macrophytic-red-alga-bangia-fuscopurpurea
#14
Tian-Jun Cao, Xing-Qi Huang, Yuan-Yuan Qu, Zhong Zhuang, Yin-Yin Deng, Shan Lu
Lycopene cyclases cyclize the open ends of acyclic lycopene (ψ,ψ-carotene) into β- or ε-ionone rings in the crucial bifurcation step of carotenoid biosynthesis. Among all carotenoid constituents, β-carotene (β,β-carotene) is found in all photosynthetic organisms, except for purple bacteria and heliobacteria, suggesting a ubiquitous distribution of lycopene β-cyclase activity in these organisms. In this work, we isolated a gene (BfLCYB) encoding a lycopene β-cyclase from Bangia fuscopurpurea, a red alga that is considered to be one of the primitive multicellular eukaryotic photosynthetic organisms and accumulates carotenoid constituents with both β- and ε-rings, including β-carotene, zeaxanthin, α-carotene (β,ε-carotene) and lutein...
April 11, 2017: Marine Drugs
https://www.readbyqxmd.com/read/28397267/stability-assessment-of-lycopene-microemulsion-prepared-using-tomato-industrial-waste-against-various-processing-conditions
#15
Atefeh Amiri-Rigi, Soleiman Abbasi
BACKGROUND: Green separation techniques are growing at a greater rate than solvent extraction owing to the constant consumer drive to "go natural". Considering the increasing evidences of the health benefits of lycopene and massive tomato industrial waste, in the present study, using microemulsion technique the lycopene was extracted from tomato industrial waste and its mean droplet size and size distribution was determined. Moreover, the effects of pasteurization, sterilization, freeze-thaw cycles and UV irradiation on the thermodynamic stability, turbidity and lycopene concentration of the lycopene microemulsion were monitored...
April 11, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28396598/cytological-and-molecular-characterization-of-carotenoid-accumulation-in-normal-and-high-lycopene-mutant-oranges
#16
Peng-Jun Lu, Chun-Yan Wang, Ting-Ting Yin, Si-Lin Zhong, Don Grierson, Kun-Song Chen, Chang-Jie Xu
Ripe Cara Cara sweet orange contains 25 times as much carotenoids in flesh as Newhall sweet orange, due to high accumulation of carotenes, mainly phytoene, lycopene and phytofluene. Only yellow globular chromoplasts were observed in Newhall flesh. Distinct yellow globular and red elongated crystalline chromoplasts were found in Cara Cara but only one type of chromoplast was present in each cell. The red crystalline chromoplasts contained lycopene as a dominant carotenoid and were associated with characteristic carotenoid sequestering structures...
April 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28386384/association-of-serum-carotenoid-retinol-and-tocopherol-concentrations-with-the-progression-of-parkinson-s-disease
#17
Ji Hyun Kim, Jinah Hwang, Eugene Shim, Eun-Jung Chung, Sung Hee Jang, Seong-Beom Koh
BACKGROUND/OBJECTIVES: A pivotal role of oxidative stress has been emphasized in the pathogenesis as well as in the disease progression of Parkinson's disease (PD). We aimed at investigating serum levels of antioxidant vitamins and elucidating whether they could be associated with the pathogenesis and progression of PD. MATERIALS/METHODS: Serum levels of retinol, α- and γ-tocopherols, α- and β-carotenes, lutein, lycopene, zeaxanthin and β-cryptoxanthin were measured and compared between 104 patients with idiopathic PD and 52 healthy controls matched for age and gender...
April 2017: Nutrition Research and Practice
https://www.readbyqxmd.com/read/28386381/anti-inflammatory-effect-of-lycopene-in-sw480-human-colorectal-cancer-cells
#18
Jae Hoon Cha, Woo Kyoung Kim, Ae Wha Ha, Myung Hwan Kim, Moon Jeong Chang
BACKGROUND/OBJECTIVES: Although the antioxidative effects of lycopene are generally known, the molecular mechanisms underlying the anti-inflammatory properties of lycopene are not fully elucidated. This study aimed to examine the role and mechanism of lycopene as an inhibitor of inflammation. METHODS/MATERIALS: Lipopolysaccharide (LPS)-stimulated SW 480 human colorectal cancer cells were treated with 0, 10, 20, and 30 µM lycopene. The MTT assay was performed to determine the effects of lycopene on cell proliferation...
April 2017: Nutrition Research and Practice
https://www.readbyqxmd.com/read/28376947/association-between-lutein-intake-and-lung-function-in-adults-the-rotterdam-study
#19
Debora Melo van Lent, Elisabeth T M Leermakers, Albert Hofman, Bruno H Stricker, Guy G Brusselle, Oscar H Franco, Lies Lahousse, Jessica C Kiefte-de Jong
Lutein, a fat-soluble carotenoid with antioxidant properties, may have an effect on respiratory health. However, the evidence is inconsistent. We aimed to cross-sectionally investigate the association between lutein intake and lung function by measuring forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC) and FEV1/FVC% in adults (aged 45-79 years). We included 4402 participants from the Rotterdam Study, a prospective cohort study in The Netherlands. Lutein intake was assessed using a validated FFQ...
March 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28375628/designing-a-new-entry-point-into-isoprenoid-metabolism-by-exploiting-fructose-6-phosphate-aldolase-side-reactivity-of-escherichia-coli
#20
Jason R King, Benjamin Michael Woolston, Gregory Stephanopoulos
The 2C-methyl-D-erythritol 4-phosphate (MEP) pathway in Escherichia coli has been highlighted for its potential to provide access to myriad isoprenoid chemicals of industrial and therapeutic relevance and discover antibiotic targets to treat microbial human pathogens. Here, we describe a metabolic engineering strategy for the de novo construction of a biosynthetic pathway that produces 1-dexoxy-D-xylulose-5-phosphate (DXP), the precursor metabolite of the MEP pathway, from the simple and renewable starting materials D-arabinose and hydroxyacetone...
April 4, 2017: ACS Synthetic Biology
keyword
keyword
40484
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"