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https://www.readbyqxmd.com/read/28943894/prevalence-and-severity-of-syndrome-z-in-women-with-metabolic-syndrome-on-waiting-list-for-bariatric-surgery-a-cross-sectional-study
#1
Eduardo Araujo Perez, Luis Vicente Franco Oliveira, Wilson Rodrigues Freitas, Carlos Alberto Malheiros, Elias Jirjoss Ilias, Anderson Soares Silva, Jessica Julioti Urbano, Patricia Clemente Oliveira, Felipe X Cepeda, Luciana M M Sampaio, Ivani C Trombetta, Humberto Delle, Daniel Gianella Neto, Sergio Roberto Nacif, Roberto Stirbulov
BACKGROUND: In recent years, obesity has become one of the most important public health problems in the world, with a growing prevalence in both developed and developing countries. Recent studies show that sleep disturbances, especially obstructive sleep apnoea (OSA) may be a manifestation of metabolic syndrome (MetS). Although the association of OSA with the MetS is largely attributed to obesity, the exact pathophysiological mechanisms and their individual characteristics still need to be identified...
2017: Diabetology & Metabolic Syndrome
https://www.readbyqxmd.com/read/28943861/a-practical-and-time-efficient-high-intensity-interval-training-program-modifies-cardio-metabolic-risk-factors-in-adults-with-risk-factors-for-type-ii-diabetes
#2
Bethan E Phillips, Benjamin M Kelly, Mats Lilja, Jesús Gustavo Ponce-González, Robert J Brogan, David L Morris, Thomas Gustafsson, William E Kraus, Philip J Atherton, Niels B J Vollaard, Olav Rooyackers, James A Timmons
INTRODUCTION: Regular physical activity (PA) can reduce the risk of developing type 2 diabetes, but adherence to time-orientated (150 min week(-1) or more) PA guidelines is very poor. A practical and time-efficient PA regime that was equally efficacious at controlling risk factors for cardio-metabolic disease is one solution to this problem. Herein, we evaluate a new time-efficient and genuinely practical high-intensity interval training (HIT) protocol in men and women with pre-existing risk factors for type 2 diabetes...
2017: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/28943558/the-serum-level-of-kl-6-is-associated-with-the-risk-of-insulin-resistance-and-new-onset-diabetes-mellitus-the-tanno-sobetsu-study
#3
Hiroshi Akasaka, Hirofumi Ohnishi, Yoshifumi Narita, Masami Kameda, Takayuki Miki, Hiroki Takahashi, Wari Yamamoto, Hitoshi Sohma, Naoya Masumori, Tetsuji Miura
Objective Inflammatory cytokines generated in visceral fat have been shown to contribute to the development of insulin resistance. The involvement of pulmonary inflammation in insulin resistance remains unclear, but smoking is known to be a risk factor for diabetes as well as chronic obstructive pulmonary disease. We herein examined the hypothesis that increased serum levels of lung interstitial injury biomarkers (SP-A, SP-D and KL-6) are associated with the risk of diabetes development. Methods For cross-sectional and longitudinal analyses, we enrolled 750 apparently healthy non-diabetic subjects who received annual examinations in 2011 or 2012 in the Tanno-Sobetsu cohort...
September 25, 2017: Internal Medicine
https://www.readbyqxmd.com/read/28940686/median-effective-dose-of-intranasal-dexmedetomidine-sedation-for-transthoracic-echocardiography-in-pediatric-patients-with-noncyanotic-congenital-heart-disease-an-up-and-down-sequential-allocation-trial
#4
Qing Yu, Yang Liu, Mang Sun, Jing Zhang, Yan Zhao, Fengzhi Liu, Shangyingying Li, Shengfen Tu
BACKGROUND: Intranasal dexmedetomidine can provide adequate sedation during short procedures. However, previous literature investigating the single-dose use of intranasal dexmedetomidine for sedation during transthoracic echocardiography in younger children is scarce, and the effects of age on sedation with intranasal dexmedetomidine remain controversial. OBJECTIVE: This study was to determine the 50% effective dose and estimate the 95% effective dose of single-dose intranasal dexmedetomidine to induce sedation in pediatric patients with noncyanotic congenital heart disease, and also determine the effect of age on the dose required for sedation...
September 20, 2017: Paediatric Anaesthesia
https://www.readbyqxmd.com/read/28940638/does-l-citrulline-supplementation-improve-exercise-blood-flow-in-older-adults
#5
Joaquin U Gonzales, Andrea Raymond, John Ashley, Youngdeok Kim
L-citrulline (Cit) increases arginine (Arg), the primary substrate for nitric oxide biosynthesis. We tested the hypothesis that muscle blood flow during exercise would be enhanced by Cit supplementation in older adults. Femoral artery blood flow was measured during calf exercise using Doppler ultrasound, and vascular conductance (FVC) was calculated in 25 older adults (13W, 12M) before and after 14 days of Cit (6 g day(-1) ) and placebo (maltodextrin) in a randomized, double-blind, crossover study. Plasma [Arg] and resting blood pressure were also measured before and after each condition...
September 20, 2017: Experimental Physiology
https://www.readbyqxmd.com/read/28939458/mind-body-interventions-for-individuals-with-heart-failure-a-systematic-review-of-randomized-trials
#6
REVIEW
Zehra Gok Metin, Deborah Ejem, J Nicholas Dionne-Odom, Yasemin Turkman, Carolina Salvador, Salpy Pamboukian, Marie Bakitas
BACKGROUND: The effects of mind-body interventions (MBIs) (e.g. Tai Chi, yoga, and meditation) for individuals with heart failure (HF) have not been systematically evaluated. METHODS AND RESULTS: We performed a systematic review of randomized controlled trials (RCTs) examining the effects of MBIs in HF. We extracted participant characteristics, MBI procedure, outcomes assessed, and main results of English language RCTs before October 2016. We identified 24 RCTs (n=1314 participants) of nine MBI types: Tai Chi (n=7), yoga (n =4), relaxation (n =4), meditation (n=2), acupuncture (n=2), biofeedback (n=2), stress management (n=1), Pilates (n=1) and reflexology (n=1)...
September 19, 2017: Journal of Cardiac Failure
https://www.readbyqxmd.com/read/28939280/clinical-hypertension-blood-pressure-variability
#7
Erum Z Malik, Basma Abdulhadi, Kenechukwu N Mezue, Edgar V Lerma, Janani Rangaswami
No abstract text is available yet for this article.
September 19, 2017: Disease-a-month: DM
https://www.readbyqxmd.com/read/28937287/the-prevalence-and-predictors-of-hypertension-in-a-national-survey-of-australian-children
#8
Nicholas G Larkins, Armando Teixeira-Pinto, Jonathan C Craig
PURPOSE: To determine the prevalence of hypertension and predictors of blood pressure (BP) in a population based survey of Australian children. SUBJECTS AND METHODS: We analysed cross-sectional data for 2071 children, aged 5-17 years, from the Australian Health Survey 2011-13. Hypertension and high-normal BP were defined by a systolic or diastolic BP greater than the 95th and 90th centiles respectively, using the National High Blood Pressure Education Program fourth report reference data...
September 22, 2017: Blood Pressure
https://www.readbyqxmd.com/read/28937241/preejection-period-as-a-sympathetic-activity-index-a-role-of-confounding-factors
#9
J Krohova, B Czippelova, Z Turianikova, Z Lazarova, I Tonhajzerova, M Javorka
In previous studies, one of the systolic time intervals - preejection period (PEP) - was used as an index of sympathetic activity reflecting the cardiac contractility. However, PEP could be also influenced by several other cardiovascular variables including preload, afterload and diastolic blood pressure (DBP). The aim of this study was to assess the behavior of the PEP together with other potentially confounding cardiovascular system characteristics in healthy humans during mental and orthostatic stress (head-up tilt test - HUT)...
September 22, 2017: Physiological Research
https://www.readbyqxmd.com/read/28937240/baroreflex-sensitivity-in-premature-infants-relation-to-the-parameters-characterizing-intrauterine-and-postnatal-condition
#10
K Haskova, M Javorka, B Czippelova, M Zibolen, K Javorka
At present, there are insufficient information about baroreflex sensitivity (BRS) and factors that determine BRS in premature newborns. The objective of this study was to determine the relationship between BRS and the characteristics that reflecting the intrauterine development (gestational age and birth weight), as well as postnatal development (postconception age and the actual weight of the child at the time of measurement). We examined 57 premature infants, who were divided into groups according to gestational age and postconception age as well as birth weight, and weight at the time of measurement...
September 22, 2017: Physiological Research
https://www.readbyqxmd.com/read/28936072/alleviating-stress-response-to-tracheal-extubation-in-neurosurgical-patients-a-comparative-study-of-two-infusion-doses-of-dexmedetomidine
#11
Ankur Luthra, Hemanshu Prabhakar, Girija Prasad Rath
BACKGROUND: Tracheal extubation is almost always associated with increase in sympathoadrenal activity may result in hypertension, tachycardia, and arrhythmias. Attempts have been made to oppose the pressor response by the use of various drugs. Dexmedetomidine decreases norepinephrine which reduces the blood pressure and the heart rate (HR). We hypothesize that the infusion of dexmedetomidine may produce more stable hemodynamics during extubation as compared to boluses. MATERIALS AND METHODS: Ninety adult patients aged 18-65 years, the American Society of Anesthesiologists Grade I-II undergoing intracranial surgeries for various neurologic problem at All India Institute of Medical Sciences were enrolled in this randomized controlled trial...
August 2017: Journal of Neurosciences in Rural Practice
https://www.readbyqxmd.com/read/28935191/circadian-rhythm-and-autonomic-dysfunction-in-presymptomatic-and-early-huntington-s-disease
#12
Elena Bellosta Diago, Jesús Pérez Pérez, Sonia Santos Lasaosa, Alejandro Viloria Alebesque, Saül Martínez Horta, Jaime Kulisevsky, Javier López Del Val
INTRODUCTION: Sleep and circadian rhythm disturbances are common in patients with neurodegenerative diseases such as Huntington's disease (HD). The aim of this study was to evaluate variability in circadian blood pressure (BP) to determine the association between abnormal circadian BP and sleep quality in patients with HD. METHODS: Cross-sectional, multicenter study of 38 HD mutation carriers (23 premanifest and 15 early stage patients) who were compared to 38 age- and sex-matched controls...
September 15, 2017: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/28935145/determinants-of-obstructive-sleep-apnea-syndrome-pro-inflammatory-state-and-dysfunction-of-high-density-lipoprotein
#13
Yusuf Karadeniz, Altan Onat, Tuğba Akbaş, Barış Şimşek, Hüsniye Yüksel, Günay Can
OBJECTIVE: The goal of this study was to determine variables preceding and predicting incident obstructive sleep apnea syndrome (OSAS) in the population at large. METHODS: Anthropometric, lipid, and non-lipid variables in participants with newly developing OSAS (n = 131) were compared with those of a cohort sample (n = 2615) of the Turkish Adult Risk Factor study. Available values preceding (by a median of 32 mo) the development of OSAS were used in multivariable Cox regression models...
November 2017: Nutrition
https://www.readbyqxmd.com/read/28934524/associations-of-sleep-duration-and-disturbances-with-hypertension-in-metropolitan-cities-of-delhi-chennai-and-karachi-in-south-asia-cross-sectional-analysis-of-the-carrs-study
#14
Roopa Shivashankar, Dimple Kondal, Mohammed K Ali, Ruby Gupta, Rajendra Pradeepa, Viswanathan Mohan, Muhammad Masood Kadir, K M Venkat Narayan, Nikhil Tandon, Dorairaj Prabhakaran, Anne Peasey
Objectives: Sleep duration and disturbances may be risk factors for hypertension. Despite the high burden of hypertension in South Asia, little is known about this relationship in this region. Methods: We analyzed population-level cross-sectional data from the Centre for Cardiometabolic Risk Reduction in South Asia (CARRS) study that recruited representative samples of adults ≥ 20 years from three cities-Delhi, Chennai (India), and Karachi (Pakistan) during 2010-2011...
September 1, 2017: Sleep
https://www.readbyqxmd.com/read/28934333/supermarket-purchase-contributes-to-nutrition-related-non-communicable-diseases-in-urban-kenya
#15
Kathrin M Demmler, Stephan Klasen, Jonathan M Nzuma, Matin Qaim
BACKGROUND: While undernutrition and related infectious diseases are still pervasive in many developing countries, the prevalence of non-communicable diseases (NCD), typically associated with high body mass index (BMI), is rapidly rising. The fast spread of supermarkets and related shifts in diets were identified as possible factors contributing to overweight and obesity in developing countries. Potential effects of supermarkets on people's health have not been analyzed up till now. OBJECTIVE: This study investigates the effects of purchasing food in supermarkets on people's BMI, as well as on health indicators such as fasting blood glucose (FBG), blood pressure (BP), and the metabolic syndrome...
2017: PloS One
https://www.readbyqxmd.com/read/28933792/a-common-haplotype-containing-functional-cacna1h-variants-is-frequently-coinherited-with-increased-tpsab1-copy-number
#16
Jonathan J Lyons, Stephanie C Stotz, Jack Chovanec, Yihui Liu, Katie L Lewis, Celeste Nelson, Thomas DiMaggio, Nina Jones, Kelly D Stone, Heejong Sung, Leslie G Biesecker, Michael A Colicos, Joshua D Milner
PurposeCaV3.2 signaling contributes to nociception, pruritus, gastrointestinal motility, anxiety, and blood pressure homeostasis. This calcium channel, encoded by CACNA1H, overlaps the human tryptase locus, wherein increased TPSAB1 copy number causes hereditary α-tryptasemia. Germ-line CACNA1H variants may contribute to the variable expressivity observed with this genetic trait.MethodsTryptase-encoding sequences at TPSAB1 and TPSB2, and TPSG1 and CACNA1H variants were genotyped in 46 families with hereditary α-tryptasemia syndrome...
September 21, 2017: Genetics in Medicine: Official Journal of the American College of Medical Genetics
https://www.readbyqxmd.com/read/28932907/effects-of-self-paced-interval-and-continuous-training-on-health-markers-in-women
#17
Luke J Connolly, Stephen J Bailey, Peter Krustrup, Jonathan Fulford, Chris Smietanka, Andrew M Jones
PURPOSE: To compare the effects of self-paced high-intensity interval and continuous cycle training on health markers in premenopausal women. METHODS: Forty-five inactive females were randomised to a high-intensity interval training (HIIT; n = 15), continuous training (CT; n = 15) or an inactive control (CON; n = 15) group. HIIT performed 5 × 5 min sets comprising repetitions of 30-s low-, 20-s moderate- and 10-s high-intensity cycling with 2 min rest between sets...
September 20, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28932306/prevalence-of-asymptomatic-arterial-hypertension-and-its-correlation-with-inflammatory-activity-in-early-rheumatoid-arthritis
#18
Ismet H Bajraktari, Sylejman Rexhepi, Idriz Berisha, Ali Lahu, Avni Kryeziu, Bastri Durmishi, Halit Bajraktari, Elton Bahtiri
BACKGROUND: Rheumatoid arthritis (RA) is a chronic systemic inflammatory disease that worsens during the course of the disease and can cause disability. Early RA refers to the onset of symptoms within the past 3 months. In RA, increased levels of mediators of inflammation may cause arterial stiffness consequently leading to arterial hypertension. AIM: The aim of this cross-sectional study was to assess the prevalence of asymptomatic arterial hypertension in early RA patients as well as the correlation with parameters of inflammation...
August 15, 2017: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28932009/relation-between-respiratory-function-and-arterial-stiffness-assessed-using-brachial-ankle-pulse-wave-velocity-in-healthy-workers
#19
Atsushi Inomoto, Rika Fukuda, Junko Deguchi, Toshihiro Toyonaga
[Purpose] Current studies report that patients with chronic obstructive pulmonary disease (COPD) may also have arteriosclerosis. This study aimed to investigate the relationship between respiratory function and arterial stiffness in healthy workers using the brachial-ankle pulse wave velocity (baPWV). [Subjects and Methods] This study included 104 male Japanese workers without COPD. We collected participant information and measured hemodynamics, body composition, and respiratory function. [Results] In the correlation analysis, baPWV showed a significant positive correlation with age, smoking index, systolic blood pressure, diastolic blood pressure, and heart rate, and a significant negative correlation with height, fat free mass, lower limb muscle mass, forced vital capacity (FVC), and forced expiratory volume in one second (FEV1)...
September 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28931367/changes-in-radial-artery-pulse-pressure-during-a-fluid-challenge-cannot-assess-fluid-responsiveness-in-patients-with-septic-shock
#20
Victor De la Puente-Diaz de Leon, Valente de Jesus Jaramillo-Rocha, Jean-Louis Teboul, Sofia Garcia-Miranda, Bernardo A Martinez-Guerra, Guillermo Dominguez-Cherit
BACKGROUND: Arterial blood pressure is the most common variable used to assess the response to a fluid challenge in routine clinical practice. The aim of this study was to evaluate the accuracy of the change in the radial artery pulse pressure (rPP) to detect the change in cardiac output after a fluid challenge in patients with septic shock. METHODS: Prospective observational study including 35 patients with septic shock in which rPP and cardiac output were measured before and after a fluid challenge with 400 mL of crystalloid solution...
January 1, 2017: Journal of Intensive Care Medicine
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