Lifang Yuan, Xu Li, Minchao Li, Rongjun Bi, Yingrui Li, Jiaping Song, Wei Li, Mingchen Yan, Huanle Luo, Caijun Sun, Yuelong Shu
Influenza remains a global health concern due to its potential to cause pandemics as a result of rapidly mutating influenza virus strains. Existing vaccines often struggle to keep up with these rapidly mutating flu viruses. Therefore, the development of a broad-spectrum peptide vaccine that can stimulate an optimal antibody response has emerged as an innovative approach to addressing the influenza threat. In this study, an immunoinformatic approach was employed to rapidly predict immunodominant epitopes from different antigens, aiming to develop an effective multiepitope influenza vaccine (MEV)...
November 13, 2023: International Journal of Biological Macromolecules