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https://www.readbyqxmd.com/read/29333780/-progress-in-exogenous-factors-affecting-the-growth-and-remodeling-of-condylar-process
#1
Peng Qiuping, Wu Jun
Condyle is a critical growth region of the mandible where mandible by endochondral ossification occurs. Condylar cartilage belongs to the secondary cartilage, which is not only affected by genetic factors but also by stress, drug intake, and other local factors. To promote the growth of the mandible, various exogenous and local factors were used to alter the biological environment of the condylar cartilage to stimulate endochondral ossification. This article reviews studies on the influence of exogenous factors on condylar growth and reconstruction...
December 1, 2017: Hua Xi Kou Qiang Yi Xue za Zhi, Huaxi Kouqiang Yixue Zazhi, West China Journal of Stomatology
https://www.readbyqxmd.com/read/29329888/associations-between-cartilage-proteoglycan-density-and-patient-outcomes-12months-following-anterior-cruciate-ligament-reconstruction
#2
Brian Pietrosimone, Daniel Nissman, Darin A Padua, J Troy Blackburn, Matthew S Harkey, Robert A Creighton, Ganesh M Kamath, Kaitlin Healy, Randy Schmitz, Jeffrey B Driban, Steve W Marshall, Joanne M Jordan, Jeffrey T Spang
BACKGROUND: Lower proteoglycan density (PGD) of the articular cartilage may be an early marker of osteoarthritis following anterior cruciate ligament (ACL) reconstruction (ACL-R). The purpose this study was to determine associations between the Knee Injury and Osteoarthritis Outcomes Score (KOOS) and PGD of the articular cartilage in the femur and tibia 12-months following ACL-R. METHODS: We evaluated KOOS pain, symptoms, function in activities of daily living (ADL), function in sport and recreation (Sport), and quality of life (QOL), as well as PGD using T1rho magnetic resonance imaging in 18 individuals 12...
January 9, 2018: Knee
https://www.readbyqxmd.com/read/29327557/-surgical-treatment-for-14-patients-with-old-fractures-of-humeral-lateral-condyle-in-children
#3
Kai Liu, Ru-Guo Shang, Yan Xiao, Jan-Wei Hu, Yong-Xin Yu
OBJECTIVE: To study clinical effects of operation for the treatment of old fractures of the humerus lateral condyle in children. METHODS: From January 2012 to January 2014 in our department, 14 children of old humeral lateral condyle fractures were treated with operation. Ten cases were male, 4 cases were female; age from 2 to 12 years old, average 5.8 years old. The initial diagnosis was type IIfracture according to the Milch ciassification, the loss of treatment in 11 cases, conservative treatment in 3 cases of nonunion after fracture displacement...
January 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29327231/loading-of-the-condylar-cartilage-can-rescue-the-effects-of-botox-on-tmj
#4
Eliane H Dutra, Mara H O'Brien, Candice Logan, Aditya Tadinada, Ravindra Nanda, Sumit Yadav
The purpose of this study is to evaluate whether the effects of botulinum neurotoxin (botox) injection into the masseter in the mandibular condylar cartilage (MCC) and subchondral bone could be rescued by compressive loading of the temporomandibular joint (TMJ). Twenty-four 6-week-old female mice (C57BL/6J) were used. Mice were divided in three groups: (1) Botox (n = 8); (2) Botox plus loading (n = 8); (3) Pure control (n = 8). Bone labels (3 and 1 day before sacrifice) and the proliferation marker EdU (2 and 1 day before sacrifice) were intraperitoneally injected into all groups of mice...
January 11, 2018: Calcified Tissue International
https://www.readbyqxmd.com/read/29325834/a-computed-tomography-scan-based-template-to-place-the-femoral-component-in-accurate-rotation-with-respect-to-the-surgical-epicondylar-axis-in-total-knee-arthroplasty
#5
Yasushi Oshima, Norishige Iizawa, Tatsunori Kataoka, Tokifumi Majima, Shinro Takai
BACKGROUND: Femoral rotational alignment is considered an essential factor for total knee arthroplasty because malrotation of femoral components results in poor outcomes. To obtain proper alignment, we developed a superimposable computed tomography (CT) scan-based template to intraoperatively determine the accurate surgical epicondylar axis (SEA), and evaluated the effectiveness of this CT template. METHODS: In the experimental group (n=55), three serial slices of CT images, including medial and lateral epicondyles, were merged into a single image, and SEA was overlaid...
January 9, 2018: Knee
https://www.readbyqxmd.com/read/29324530/early-results-of-single-plug-autologous-osteochondral-grafting-for-osteochondritis-dissecans-of-the-capitellum-in-adolescents
#6
Donald S Bae, Eitan M Ingall, Patricia E Miller, Katherine Eisenberg
BACKGROUND: Osteochondral autologous transplantation surgery (OATS) has been advocated for unstable osetochondritis dissecans (OCD) lesions of the adolescent capitellum, though limited information is available regarding clinical and radiographic results in North American patients. We hypothesize that single-plug OATS is safe and effective in alleviating pain and restoring function in unstable OCD. METHODS: Twenty-eight patients with unstable OCD treated with single-plug OATS were evaluated...
January 10, 2018: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/29323806/spine-and-spinal-cord-injuries-after-falls-from-tree-stands-during-the-wisconsin-deer-hunting-season
#7
Kimberly Hamilton, Brandon Rocque, Nathaniel Brooks
BACKGROUND: Deer hunting is popular in much of the United States. In Wisconsin, use of tree stands for hunting is common. Spine surgeons at a Level 1 Trauma Center observed a high incidence of spine and spinal cord injury due to falls from tree stands while hunting. This study's purpose is to systematically characterize and classify those injuries. METHODS: We reviewed the University of Wisconsin Hospital and Clinics' trauma database for tree stand-related injuries from 1999 to 2013...
November 2017: WMJ: Official Publication of the State Medical Society of Wisconsin
https://www.readbyqxmd.com/read/29322877/topographical-variation-of-human-femoral-articular-cartilage-thickness-t1rho-and-t2-relaxation-times-is-related-to-local-loading-during-walking
#8
Sam Van Rossom, Mariska Wesseling, Dieter Van Assche, Ilse Jonkers
Objective Early detection of degenerative changes in the cartilage matrix composition is essential for evaluating early interventions that slow down osteoarthritis (OA) initiation. T1rho and T2 relaxation times were found to be effective for detecting early changes in proteoglycan and collagen content. To use these magnetic resonance imaging (MRI) methods, it is important to document the topographical variation in cartilage thickness, T1rho and T2 relaxation times in a healthy population. As OA is partially mechanically driven, the relation between these MRI-based parameters and localized mechanical loading during walking was investigated...
January 1, 2018: Cartilage
https://www.readbyqxmd.com/read/29322857/morphometric-analysis-for-evaluating-the-relation-between-incisal-guidance-angle-occlusal-plane-angle-and-functional-temporomandibular-joint-shape-variation
#9
Seulgi Han, Sang Min Shin, Yong-Seok Choi, So Yeun Kim, Ching-Chang Ko, Yong-Il Kim
OBJECTIVE: The correlations between morphology of the temporomandibular joint structure, the anterior guidance angle, and occlusal plane were investigated. MATERIALS AND METHODS: A cone beam computed tomography analysis was performed in 158 patients (86 women and 72 men). 3D software was employed to obtain the coordinates of the shape of the incisal guidance angle, occlusal guidance angle, articular fossa, and mandibular condyle. Generalized Procrustes analysis including principal components analysis (PCA) were performed and produced principal components (PCs) scores of each shape and their centroid size (CS)...
January 11, 2018: Acta Odontologica Scandinavica
https://www.readbyqxmd.com/read/29318429/effect-of-intra-articular-injection-of-intermediate-weight-hyaluronic-acid-on-hip-and-knee-cartilage-in-vivo-evaluation-using-t2-mapping
#10
Giulio Ferrero, Luca Maria Sconfienza, Francesco Fiz, Emanuele Fabbro, Angelo Corazza, Daniele Dettore, Davide Orlandi, Carlo Castellazzo, Stefano Tornago, Giovanni Serafini
OBJECTIVES: We used T2 mapping to quantify the effect of intra-articular hyaluronic acid administration (IAHAA) on cartilage with correlation to clinical symptoms. METHODS: One hundred two patients with clinical and MRI diagnosis of hip or knee grade I-III chondropathy were prospectively included. All patients received a standard MRI examination of the affected hip/knee (one joint/patient) and T2-mapping multiecho sequence for cartilage evaluation. T2 values of all slices were averaged and used for analysis...
January 9, 2018: European Radiology
https://www.readbyqxmd.com/read/29314864/outcomes-of-osteochondral-allograft-transplantation-with-and-without-concomitant-meniscus-allograft-transplantation-a-comparative-matched-group-analysis
#11
Rachel M Frank, Simon Lee, Eric J Cotter, Charles P Hannon, Timothy Leroux, Brian J Cole
BACKGROUND: Osteochondral allograft transplantation (OCA) is often performed with concomitant meniscus allograft transplantation (MAT) as a strategy for knee joint preservation, although to date, the effect of concomitant MAT on outcomes and failure rates after OCA has not been assessed. PURPOSE: To determine clinical outcomes for patients undergoing OCA with MAT as compared with a matched cohort of patients undergoing isolated OCA. STUDY DESIGN: Control study; Level of evidence, 3...
January 1, 2018: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29311146/impact-of-broad-regulatory-regions-on-gdf5-expression-and-function-in-knee-development-and-susceptibility-to-osteoarthritis
#12
Steve K Pregizer, Ata M Kiapour, Mariel Young, Hao Chen, Michael Schoor, Zun Liu, Jiaxue Cao, Vicki Rosen, Terence D Capellini
OBJECTIVES: Given the role of growth and differentiation factor 5 (GDF5) in knee development and osteoarthritis risk, we sought to characterise knee defects resulting from Gdf5 loss of function and how its regulatory regions control knee formation and morphology. METHODS: The brachypodism (bp) mouse line, which harbours an inactivating mutation in Gdf5, was used to survey how Gdf5 loss of function impacts knee morphology, while two transgenic Gdf5 reporter bacterial artificial chromosome mouse lines were used to assess the spatiotemporal activity and function of Gdf5 regulatory sequences in the context of clinically relevant knee anatomical features...
January 8, 2018: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/29310844/modification-of-the-measurement-of-the-major-variables-in-mandibular-condylar-fractures-angulation-of-sidewards-displacement-and-shortening-of-the-height-of-the-ramus
#13
S P Chang, Y Yang, L Q Shi, Y W Liu, Y Liu, Q Ma
Our aim was to improve the accuracy of measurement of the angulation and the shortening of the height of the ramus in fractures of the mandibular condyle using modified methods. We analysed spiral computed tomography (CT) of 67 unilateral fractures with the OsiriX v 5.0 (©Pixmeo Sarl) and Mimics 19.0 (©2016 Materialise NV, Belgium) and analysed them with SPSS (version 24.0, IBM® SPSS®). Angulation was measured using both the traditional method and our modified method. The results showed significant difference (p = 0...
January 5, 2018: British Journal of Oral & Maxillofacial Surgery
https://www.readbyqxmd.com/read/29310333/epidemiologic-features-and-management-of-elbow-dislocation-with-associated-fracture-in-pediatric-population
#14
Xuemin Lu, Guisen Yan, Ming Lu, Yuan Guo
This study was conducted to explore epidemiologic features of traumatic elbow dislocation with associated fractures in pediatric population following appropriate treatment options.Incidence of elbow dislocation with associated fractures was analyzed in 67 children using elbow radiographs. Treatment for the displaced elbow joint was performed by closed reduction and proper immobilization. Surgical intervention was applied to restore the correct alignment of the fracture. Mayo Elbow Performance Score (MEPS) was used to measure elbow joint function...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29305289/prediction-models-to-improve-the-diagnostic-value-of-plain-radiographs-in-children-with-complete-discoid-lateral-meniscus
#15
Yong-Beom Park, Chul-Won Ha, Jae Won Jang, Manyoung Kim, Han-Jun Lee, Yong-Geun Park
PURPOSE: To develop prediction models to improve the diagnostic utility of plain radiographs for the diagnosis of complete discoid lateral meniscus by combining previously reported radiographic findings. METHODS: Patients ages 5 to 16 years with complete discoid lateral meniscus confirmed by arthroscopy or magnetic resonance imaging were included. Patients with insufficient radiographs were excluded. Normal control subjects were randomly sampled by age and sex matching...
January 2, 2018: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29304966/editorial-commentary-osteochondral-autograft-transplantation-for-treatment-of-spontaneous-osteonecrosis-of-the-medial-femoral-condyle
#16
EDITORIAL
Jüri-Toomas Kartus
Osteochondral autograft transplantation together with high tibial osteotomy is a successful treatment of spontaneous osteonecrosis of the medial femoral condyle independent of lesion size.
January 2018: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29303761/simple-bone-cyst-rare-incidental-finding-in-the-mandibular-condyle-by-cone-beam-computed-tomography
#17
Eliana Dantas da Costa, Gina Delia Roque-Torres, Priscila Dias Peyneau, Luís Roberto Godolfim, Francisco Haiter Neto, Solange Maria Almeida
The simple bone cyst (SBC) is a benign intraosseous lesion that is considered to be a pseudocyst because the cystic cavity does not present an epithelial lining. The most accepted theory regarding its etiology is that the SBC develops when the blood clot fails to organize subsequent to bleeding caused by trauma. The SBC is asymptomatic, and therefore the diagnosis is made through routine imaging examinations. In imaging examinations, the lesion is characterized by a radiolucent, unilocular, well-delimited appearance and an irregular or scalloped contour with or without a sclerotic halo...
January 2018: General Dentistry
https://www.readbyqxmd.com/read/29299611/bone-morphology-and-morphometry-of-the-lateral-femoral-condyle-is-a-risk-factor-for-acl-injury
#18
Sebastiano Vasta, Renato Andrade, Rogério Pereira, Ricardo Bastos, Antonino Giulio Battaglia, Rocco Papalia, João Espregueira-Mendes
PURPOSE: The purpose of this study was to investigate the influence of the knee lateral compartment bony morphology and morphometry on risk of sustaining an anterior cruciate ligament (ACL) injury. METHODS: A total of 400 age and sex-matched patients (200 ACL-ruptured and 200 ACL-intact) were included. The lateral femoral and tibial bone morphology and morphometric parameters were measured on knee lateral radiographs, taken at 30° of knee flexion with overlapping of the femoral condyles...
January 3, 2018: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/29298566/osteochondral-interface-stiffening-in-mandibular-condylar-osteoarthritis
#19
J Zhang, L Liao, J Zhu, X Wan, M Xie, H Zhang, M Zhang, L Lu, H Yang, D Jing, X Liu, S Yu, X L Lu, C Chen, Z Shan, M Wang
Osteoarthritis (OA) of the temporomandibular joint (TMJ) is associated with dental biomechanics. A major change during OA progression is the ossification of the osteochondral interface. This study investigated the formation, radiological detectability, and mechanical property of the osteochondral interface at an early stage, the pathogenesis significance of which in OA progression is of clinical interest and remains elusive for the TMJ. Unilateral anterior crossbite (UAC) was performed on 6-wk-old rats as we previously reported...
December 1, 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/29286211/characterization-of-costal-cartilage-and-its-suitability-as-a-cell-source-for-articular-cartilage-tissue-engineering
#20
Le W Huwe, Wendy E Brown, Jerry C Hu, Kyriacos A Athanasiou
Costal cartilage is a promising donor source of chondrocytes to alleviate cell scarcity in articular cartilage tissue engineering. Limited knowledge exists, however, on costal cartilage characteristics. This study describes the characterization of costal cartilage and articular cartilage properties and compares neocartilage engineered with costal chondrocytes to native articular cartilage, all within a sheep model. Specifically, we 1) quantitatively characterized the properties of costal cartilage in comparison to patellofemoral articular cartilage, and 2) evaluated the quality of neocartilage derived from costal chondrocytes for potential use in articular cartilage regeneration...
December 29, 2017: Journal of Tissue Engineering and Regenerative Medicine
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