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vitreomacular traction

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https://www.readbyqxmd.com/read/29664985/photodynamic-therapy-induced-macular-hole
#1
Margaret A Greven, Loh-Shan B Leung
A 72-year-old female with neovascular macular degeneration refractory to anti-vascular endothelial growth factor injections underwent photodynamic therapy and subsequently developed a macular hole (MH) associated with vitreomacular traction. After a period of observation, the MH enlarged. Pars plana vitrectomy was performed, and the MH was closed successfully. [Ophthalmic Surg Lasers Imaging Retina. 2018;49:270-272.].
April 1, 2018: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/29621042/experience-with-ocriplasmin-in-patients-with-vitreomacular-traction-syndrome-a-retrospective-study-of-10-patients
#2
Caroline Bormann, Bianca C Apitzsch, Anke Habermann, Ute Hammer, Thomas Hammer
PURPOSE: To assess the efficacy of ocriplasmin in patients with vitreomacular traction (VMT) syndrome <1,500 μm with or without a full-thickness macular holes of <400 μm. METHODS: In this study, a retrospective analysis of 10 eyes of 10 patients with VMT who were treated with ocriplasmin between December 2014 and January 2016 was performed. Ocriplasmin 0.125 mg was injected only once in all cases. Outcome measures included the detachment of VMT, best-corrected visual acuity, the evaluation of optical coherence tomography, including the closure of full-thickness macular holes, and the reduction of macular edema (if present) and the decrease of metamorphopsia if present...
April 4, 2018: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/29595569/spectral-domain-optical-coherence-tomography-findings-and-visual-outcome-after-treatment-for-vitreomacular-traction
#3
Peng Sun, Rachel M Tandias, Gina Yu, Jorge G Arroyo
PURPOSE: To evaluate the capacity of spectral domain optical coherence tomography macular findings to predict best-corrected visual acuity (BCVA) outcomes after treatment for symptomatic vitreomacular traction. METHODS: This consecutive, retrospective study included 24 patients (29 eyes) who experienced vitreomacular traction release with pneumatic vitreolysis (n = 9), intravitreal ocriplasmin (n = 6), or pars plana vitrectomy (n = 14). Preoperative and postoperative spectral domain optical coherence tomography images were used to determine the cone outer segment tips (COST) line, inner segment/outer segment line, and other frequently used features...
March 27, 2018: Retina
https://www.readbyqxmd.com/read/29491704/hybrid-wide-angle-viewing-endoscopic-vitrectomy-using-a-3d-visualization-system
#4
Mihori Kita, Yuki Mori, Sachiyo Hama
Purpose: To introduce a hybrid wide-angle viewing-endoscopic vitrectomy, which we have reported, using a 3D visualization system developed recently. Subjects and methods: We report a single center, retrospective, consecutive surgical case series of 113 eyes that underwent 25 G vitrectomy (rhegmatogenous retinal detachment or proliferative vitreoretinopathy, 49 eyes; epiretinal membrane, 18 eyes; proliferative diabetic retinopathy, 17 eyes; vitreous opacity or vitreous hemorrhage, 11 eyes; macular hole, 11 eyes; vitreomacular traction syndrome, 4 eyes; and luxation of intraocular lens, 3 eyes)...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29468225/multimodal-imaging-of-macular-subretinal-deposits-following-intravitreal-ocriplasmin-injection
#5
Nicholas Chow, Thomas Hong, Andrew Chang
Purpose: Ocriplasmin is effective in closing macular holes due to vitreomacular traction. We present a case of macular subretinal material deposition observed with spectral-domain optical coherence tomography (SD-OCT) and multimodal imaging, following successful closure of a macular hole following intravitreal ocriplasmin injection. Observations: An 81-year-old male presented with decreased vision in the left eye due to a full-thickness macular hole secondary to vitreomacular traction...
March 2018: American Journal of Ophthalmology Case Reports
https://www.readbyqxmd.com/read/29468216/central-retinal-artery-occlusion-during-vitrectomy-immediate-retinal-revascularization-following-induction-of-posterior-vitreous-detachment
#6
Abdallah A Ellabban, Ajay D Patil, Mark T Costen, Atiq R Babar
Purpose: To describe a patient with acute central retinal artery occlusion (CRAO) during vitrectomy surgery and the possible role of vitrectomy in acute CRAO management. Observations: An 84-year-old man presented with broad vitreomacular traction and epiretinal membrane in the right eye. Preoperative assessment clearly showed normal retinal vasculature. On starting vitrectomy, complete CRAO with marked segmentation of all retinal vessels was noted. Vitrectomy was performed in the usual manner and once the posterior hyaloid detached from the disc, immediate complete revascularization of the retinal vessels was noted...
March 2018: American Journal of Ophthalmology Case Reports
https://www.readbyqxmd.com/read/29390407/influence-of-vitreomacular-interface-on-anti-vascular-endothelial-growth-factor-treatment-outcomes-in-neovascular-age-related-macular-degeneration-a-moose-compliant-meta-analysis
#7
Meng Gao, LiMei Liu, XiDa Liang, YanPing Yu, XinXin Liu, Wu Liu
The aim of the study was to evaluate the influence of vitreomacular interface configuration on treatment outcomes after intravitreal anti-vascular endothelial growth factor (anti-VEGF) therapy for neovascular age-related macular degeneration (AMD).The Pubmed, Embase, and Cochrane Central Register of Controlled Trials databases were searched to identify relevant prospective or retrospective studies that evaluate the influence of vitreomacular adhesion (VMA) or vitreomacular traction (VMT) on functional and anatomical outcomes in neovascular AMD patients treated with anti-VEGF agents...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29369516/prevalence-of-optical-coherence-tomography-detected-vitreomacular-interface-disorders-the-maastricht-study
#8
Ilona Liesenborghs, Eline E B De Clerck, Tos T J M Berendschot, Fleur Goezinne, Miranda T Schram, Ronald M A Henry, Coen D A Stehouwer, Carroll A B Webers, Jan S A G Schouten
PURPOSE: To calculate the prevalence of all vitreomacular interface (VMI) disorders and stratify according to age, sex and (pre)diabetes status. METHODS: The presence of VMI disorders was assessed in 2660 participants aged between 40 and 75 years from The Maastricht Study who had a gradable macular spectral-domain optical coherence tomography (SD-OCT) volume scan in at least one eye [mean 59.7 ± 8.2 years, 50.2% men, 1531 normal glucose metabolism (NGM), 401 prediabetes, 728 type 2 diabetes (DM2, oversampled)]...
January 25, 2018: Acta Ophthalmologica
https://www.readbyqxmd.com/read/29346240/response-of-inflammatory-cystoid-macular-edema-to-treatment-using-oral-acetazolamide
#9
Kathryn L Pepple, Macklin H Nguyen, Kaivon Pakzad-Vaezi, Kathleen Williamson, Naomi Odell, Cecilia Lee, Thellea K Leveque, Russell N Van Gelder
PURPOSE: To determine the treatment effect of oral acetazolamide on refractory inflammatory macular edema. METHODS: A retrospective review of identified patients with uveitic or pseudophakic macular edema treated using acetazolamide between 2007 and 2014. Visual acuity and central macular subfield thickness was determined at baseline and at first follow-up. Baseline optical coherence tomography features were analyzed as predictors of acetazolamide response. RESULTS: Sixteen patients (19 eyes) of 61 screened met all criteria...
January 16, 2018: Retina
https://www.readbyqxmd.com/read/29219961/measurement-of-full-thickness-macular-hole-size-using-en-face-optical-coherence-tomography
#10
E Philippakis, M Legrand, M El Sanharawi, A Erginay, A Couturier, R Tadayoni
PurposeTo assess the feasibility and interest of measuring macular hole (MH) size using en face optical coherence tomography (OCT) compared with manual diameter measurements on B-scans.MethodsAmong our previously published series of 100 patients operated for primary MH, patients whose images were acquired with Cirrus 5000 HD-OCT (Carl Zeiss Meditec) with a quality signal strength >5/10 were included. Three segmentations (internal limiting membrane, horizontal, and retinal pigment epithelium (RPE)) were compared for obtaining the most appropriate en face image...
March 2018: Eye
https://www.readbyqxmd.com/read/29217147/a-study-of-the-natural-history-of-vitreomacular-traction-syndrome-by-oct
#11
Marie-Hélène Errera, Sidath E Liyanage, Petros Petrou, Pearse A Keane, Rene Moya, Eric Ezra, David G Charteris, Louisa Wickham
PURPOSE: To examine the natural history of vitreomacular traction syndrome (VMTS) in the absence of other ocular comorbidities. DESIGN: Retrospective clinical case series. PARTICIPANTS: A total of 183 eyes of 159 patients diagnosed with VMTS with no other ocular comorbidity. METHODS: Patients with VMTS were identified from an OCT database at Moorfields Eye Hospital, London. Sequential OCT scans and patient notes were reviewed over a minimum period of 6 months...
December 4, 2017: Ophthalmology
https://www.readbyqxmd.com/read/29214073/assessment-of-ocriplasmin-effects-on-the-vitreoretinal-compartment-in-porcine-and-human-model-systems
#12
Bart Jonckx, Michael Porcu, Aurelie Candi, Isabelle Etienne, Philippe Barbeaux, Jean H M Feyen
Ocriplasmin (Jetrea®) is a recombinant protease used to treat vitreomacular traction. To gain insight into vitreoretinal observations reported after ocriplasmin treatment, we have developed an in vivo porcine ocriplasmin-induced posterior vitreous detachment (PVD) model in which we investigated vitreoretinal tissues by optical coherence tomography, histology, and cytokine profiling. Eight weeks postinjection, ocriplasmin yielded PVD in 82% of eyes. Subretinal fluid (85%) and vitreous hyperreflective spots (45%) were resolved by week 3...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29197164/epidemiology-and-morphology-of-full-thickness-macular-holes
#13
Vegard Asgeir Forsaa, Birger Lindtjørn, Jan Terje Kvaløy, Torbjørn Frøystein, Jørgen Krohn
PURPOSE: To investigate the incidence of full-thickness macular holes (FTMHs) and their morphological features according to the International Vitreomacular Traction Study (IVTS) classification. METHODS: The clinical records of all new patients with FTMH, referred between 2008 and 2014, were reviewed for demographics, cause of the FTMH, age at diagnosis, symptom duration, laterality, visual acuity (VA), axial length and lens status. A detailed analysis of the patients' spectral domain optical coherence tomography (SD-OCT) images was performed, and the primary FTMHs were classified in clinical stages according to the IVTS classification...
December 2, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/29190243/factors-associated-with-serous-retinal-detachment-in-highly-myopic-eyes-with-vertical-oval-shaped-dome
#14
Antonio García-Ben, María J Morillo Sanchez, Ana Gonzalez Gómez, Ignacio García-Basterra, Antonio Soler García, Jose M García-Campos
PURPOSE: This study investigated factors associated with persistent serous retinal detachment in highly myopic eyes with vertical oval-shaped domes. METHODS: Twenty-eight highly myopic patients (40 eyes) with smooth macular elevations related to a vertical oval-shaped dome were recruited. Serous retinal detachment was investigated; 11 eyes had persistent submacular fluid (study group) and 29 eyes lacked submacular fluid (control group). All patients underwent complete ophthalmologic examinations, including axial-length measurement and fluorescein angiography...
November 22, 2017: Retina
https://www.readbyqxmd.com/read/29180844/vitreoretinal-interface-abnormalities-in-diabetic-macular-edema-and-effectiveness-of-anti-vegf-therapy-an-optical-coherence-tomography-study
#15
Alexei N Kulikov, Sergei V Sosnovskii, Roman D Berezin, Dmitrii S Maltsev, Dzhambulat H Oskanov, Nikolai A Gribanov
Purpose: To study vitreoretinal interface (VRI) abnormalities in diabetic macular edema (DME) and the influence of these on the effectiveness of intravitreal anti-vascular endothelial growth factor (VEGF) therapy. Methods: VRI status and central retinal thickness (CRT) were evaluated using line and 3D-reference scans obtained using spectral domain-optical coherence tomography RTVue-100 before and 1 month after intravitreal anti-VEGF injection (IVI). VRI status was categorized into five subgroups: normal VRI, retinal surface wrinkling associated with the eccentric epiretinal membrane (ERM), ERM involving the macular center, vitreomacular adhesion (VMA), and vitreomacular traction (VMT)...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29179221/-vitreomacular-traction-following-anti-vegf-therapy-two-cases
#16
Sophie Helene Wallraf, Kristina Markova, Christos Haritoglou
Vitreomacular traction syndrome (VMTS) is defined as an incomplete or anomalous posterior vitreous detachment resulting in tractional forces at the macular region. In the context of anti-VEGF therapy, the formation of vitreoretinal traction has mainly been reported as a potential complication of VEGF inhibition in ischemic proliferative retinal disease, such as proliferative diabetic retinopathy. In this report, we present two patients who developed VMTS during anti-VEGF therapy for exudative age-related macular degeneration and diabetic macular edema...
November 27, 2017: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/29166888/cyclic-stretch-induced-retinal-pigment-epithelial-cell-apoptosis-and-cytokine-changes
#17
Shen Wu, Qingjun Lu, Ningli Wang, Jingxue Zhang, Qian Liu, Meng Gao, Jinqiu Chen, Wu Liu, Liang Xu
BACKGROUND: The pathogenesis of age-related macular degeneration (AMD) is complex. It has been shown that vitreomacular traction (VMT) plays a role in the pathogenesis of AMD. We speculate that the continuous stretch induced by VMT might impair the function of retinal pigment epithelium (RPE) cells and it might also be involved in the progression of AMD. METHODS: Cultured ARPE-19 cells were subjected to cyclic stretch on the Flexcell Strain system at a level of 25% increment on the surface area for 8 h, 14 h, 20 h, 24 h...
November 22, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/29164327/macular-retinoschisis-in-eyes-with-glaucomatous-optic-neuropathy-vitrectomy-and-natural-course
#18
Tadanobu Yoshikawa, Chihiro Yamanaka, Takamasa Kinoshita, Shohei Morikawa, Nahoko Ogata
PURPOSE: Our purpose was to determine the effectiveness of vitrectomy in resolving the macular retinoschisis in an eye with glaucomatous optic neuropathy and also to determine the natural course of macular retinoschisis. METHODS: This was a retrospective case series of patients who were diagnosed with macular retinoschisis and glaucomatous optic neuropathy. Fourteen eyes of 13 patients were studied. Patients with high myopia, vitreomacular traction syndrome, and the pit macular syndrome were excluded...
November 21, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/29141079/visual-function-response-to-ocriplasmin-for-the-treatment-of-vitreomacular-traction-and-macular-hole-the-oasis-study
#19
RANDOMIZED CONTROLLED TRIAL
Benedicte Lescrauwaet, Luc Duchateau, Thomas Verstraeten, Timothy L Jackson
Purpose: To assess the effect of ocriplasmin on visual function response (VFR) measured using visual acuity (VA) and vision-related quality of life, and to quantify the association between release of vitreomacular adhesion (VMA) at day 28 and VFR. Methods: Prespecified analysis of secondary endpoints from a randomized controlled trial. Of 220 participants with symptomatic VMA/vitreomacular traction (VMT), including VMT associated with a macular hole up to 400 μm, 146 received a single intravitreal injection of 125 μg ocriplasmin and 74 a sham injection...
November 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/29138978/-morphology-of-the-vitreoretinal-interface-in-fellow-eyes-of-patients-with-full-thickness-macular-holes
#20
J E Klaas, S Burzer, S Abraham, N Feucht, C P Lohmann, M Maier
PURPOSE: We performed a retrospective, observational clinical study to evaluate the vitreoretinal interface (VRI) in fellow eyes of patients with full thickness macular holes (FTMH) based on spectral domain optical coherence tomography (SD-OCT) examinations. METHODS: The VRI in fellow eyes of 38 patients with idiopathic FTMH, 6 of which had concomitant vitreomacular traction (VMT) and the VRI of 32 patients with FTMH with complete resolution of VMT were examined by SD-OCT for the presence of vitreomacular adhesion (VMA), VMT and the formation of FTMH, lamellar macular holes (LMH), macular pseudoholes (MPH) or epiretinal membranes (ERM)...
November 14, 2017: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
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