Pengcheng Liu, Dapeng Chen, Jintu Lou, Jiancheng Lin, Caizhi Huang, Yun Zou, Cai Wong, Haiming Wu, Gangfeng Yan, Jing Liu, Zhenwen Zhou, Fei Gao, Ling Gao, Guangfeng Long, Lijuan Ma, Shuzhi Dai, Wei Qu, Liya Mo, Shiqiang Shang, Jin Xu
OBJECTIVES: The aim of this study is to assess Heparin-binding protein (HBP) as a diagnostic and prognostic biomarker of severe sepsis in the pediatric intensive care unit (PICU). METHODS: A multicenter, prospective study was conducted among children with sepsis in nine PICUs in China from October 2019 to June 2021. Plasma levels of HBP, procalcitonin (PCT), C-reactive protein (CRP), lactate, and white blood cell (WBC) count were determined at enrollment and 72 hours after enrollment...
November 29, 2022: Clinica Chimica Acta; International Journal of Clinical Chemistry