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https://www.readbyqxmd.com/read/27879642/curcumin-and-boswellia-serrata-modulate-the-glyco-oxidative-status-and-lipo-oxidation-in-master-athletes
#1
Nino Cristiano Chilelli, Eugenio Ragazzi, Romina Valentini, Chiara Cosma, Stefania Ferraresso, Annunziata Lapolla, Giovanni Sartore
BACKGROUND: Chronic intensive exercise is associated with a greater induction of oxidative stress and with an excess of endogenous advanced glycation end-products (AGEs). Curcumin can reduce the accumulation of AGEs in vitro and in animal models. We examined whether supplementation with curcumin and Boswellia serrata (BSE) gum resin for 3 months could affect plasma levels of markers of oxidative stress, inflammation, and glycation in healthy master cyclists. METHODS: Forty-seven healthy male athletes were randomly assigned to Group 1, consisting of 22 subjects given a Mediterranean diet (MD) alone (MD group), and Group 2 consisted of 25 subjects given a MD plus curcumin and BSE (curcumin/BSE group)...
November 21, 2016: Nutrients
https://www.readbyqxmd.com/read/27822272/combined-administration-of-melissa-officinalis-and-boswellia-serrata-extracts-in-an-animal-model-of-memory
#2
Mohaddese Mahboubi, Mohsen Taghizadeh, Sayyed Alireza Talaei, Sayyed Mehdi Takht Firozeh, Ali Akbar Rashidi, Omid Reza Tamtaji
BACKGROUND: Boswellia serrata and Melissa officinalis is traditionally used for its memory enhancing effects. OBJECTIVES: In this study, we evaluated the protective effects of combined form of these extracts on memory improvement of scopolamine treated rats by the Morris water maze method. MATERIALS AND METHODS: Two groups (group 1 and 2) of animals were pretreated with combined extracts of B. serrata and M. officinalis (200, 400 mg/Kg body weight) for four weeks and then, 30 minutes before starting the experiment scopolamine was injected (0...
September 2016: Iranian Journal of Psychiatry and Behavioral Sciences
https://www.readbyqxmd.com/read/27782055/quantitative-determination-of-3-o-acetyl-11-keto-%C3%AE-boswellic-acid-akba-and-other-boswellic-acids-in-boswellia-sacra-flueck-syn-b-carteri-birdw-and-boswellia-serrata-roxb
#3
Giuseppe Mannino, Andrea Occhipinti, Massimo E Maffei
Boswellia serrata and Boswellia sacra (syn. B. carteri) are important medicinal plants widely used for their content of bioactive lipophilic triterpenes. The qualitative and quantitative determination of boswellic acids (BAs) is important for their use in dietary supplements aimed to provide a support for osteoarthritic and inflammatory diseases. We used High Performance Liquid Chromatography (HPLC)-Diode Array Detector (DAD) coupled to ElectroSpray Ionization and tandem Mass Spectrometry (ESI-MS/MS) for the qualitative and quantitative determination of BAs extracted from the gum resins of B...
October 6, 2016: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/27775780/a-novel-lecithin-based-delivery-form-of-boswellic-acids-casperome%C3%A2-for-the-management-of-osteo-muscular-pain-a-registry-study-in-young-rugby-players
#4
F Franceschi, S Togni, G Belcaro, M Dugall, R Luzzi, A Ledda, L Pellegrini, R Eggenhoffner, L Giacomelli
OBJECTIVE: Several experimental studies and clinical trials support the potential of Boswellia serrata extracts (BSE) for the treatment of various inflammatory diseases. The aim of this registry study was to assess the safety and the efficacy of a novel lecithin-based delivery form of Boswellia serrata extract (Casperome®) in the supportive management of osteo-muscular pain. PATIENTS AND METHODS: 52 healthy young rugby players with acute knee pain and inflammation were recruited...
October 2016: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/27774904/medicinal-plants-for-the-treatment-of-asthma-a-traditional-persian-medicine-perspective
#5
Behjat Javadi, Amirhossein Sahebkar, Seyed Ahmad Emami
OBJECTIVE: To search major Traditional Persian Medicine (TPM) textbooks for medicinal plants used to treat asthma. The conformity of the TPM findings on the anti-asthmatic efficacy of plants with the findings of pharmacological studies was also explored. METHODS: Major TPM textbooks were hand searched to find medicinal plants used for the treatment of asthma. Scientific names of TPM-suggested plants were determined using botanical databases and were used for a multi-database electronic search in PubMed, Scopus, ScienceDirect and Google Scholar databases...
October 21, 2016: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/27769076/the-role-of-dietary-supplements-in-inflammatory-bowel-disease-a-systematic-review
#6
Roberta E Rossi, Tara Whyand, Charles D Murray, Mark I Hamilton, Dario Conte, Martyn E Caplin
Inflammatory bowel diseases (IBD) are chronic immune disorders of unclear aetiology. Dietary deficiencies may be a potential pathogenic factor in their development. Patients often take food supplements without knowledge of any evidence base. We have therefore assessed the evidence for food supplementation in the management of IBD. A PubMed search was performed for the terms Inflammatory bowel disease; nutritional deficiencies; dietary supplements; curcumin; green tea; vitamin D/other vitamins; folic acid; iron; zinc; probiotics; andrographis paniculata; and boswellia serrate...
December 2016: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/27765357/a-single-dose-randomized-cross-over-two-way-open-label-study-for-comparing-the-absorption-of-boswellic-acids-and-its-lecithin-formulation
#7
Antonella Riva, Paolo Morazzoni, Christian Artaria, Pietro Allegrini, Jürgen Meins, Daniele Savio, Giovanni Appendino, Manfred Schubert-Zsilavecz, Mona Abdel-Tawab
BACKGROUND: The oral administration of the gum resin extracts of Indian frankincense (Boswellia serrata Roxb. ex Colebr) results in very low plasma concentrations of boswellic acids (BAs), being far below the pharmacologically active concentrations required in vitro for anti-inflammatory activity. For that reason the use of Indian frankincense in clinical practice and pharmaceutical development has substantially lagged behind. Recently the application of new formulation technologies resulted in a formulation of frankincense extract with lecithin, which revealed improved absorption and tissue penetration of BAs in a rodent study, leading for the first time to plasma concentrations of BAs in the range of their anti-inflammatory activity...
November 15, 2016: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
https://www.readbyqxmd.com/read/27730658/synergistic-antimicrobial-activity-of-boswellia-serrata-roxb-ex-colebr-burseraceae-essential-oil-with-various-azoles-against-pathogens-associated-with-skin-scalp-and-nail-infections
#8
S Sadhasivam, S Palanivel, S Ghosh
: Antimicrobials from natural sources have gained immense importance in recent times to combat the global challenge of antibiotic resistance. Essential oils are implicated in antimicrobial action against several species. Here, we have screened nine commercially available essential oils for their antimicrobial activity against organisms associated with skin, scalp and nail infections mainly Propionibacterium acnes, Malassezia spp., Candida albicans and Trichophyton spp. Among nine essential oils, Boswellia serrata essential oil demonstrated superior antimicrobial activity against all the micro-organisms and surprisingly it showed maximum activity against Trichophyton spp...
December 2016: Letters in Applied Microbiology
https://www.readbyqxmd.com/read/27681813/clinical-comparison-of-oral-administration-and-viscosupplementation-of-hyaluronic-acid-ha-in-early-knee-osteoarthritis
#9
M Ricci, G M Micheloni, M Berti, F Perusi, E Sambugaro, E Vecchini, B Magnan
PURPOSE: Osteoarthritis (OA) is a progressive, chronic and degenerative joint disease characterized by a loss of articular cartilage. Treatment of OA is largely palliative based on nonsteroidal anti-inflammatory drugs, opioids and injections of steroids. Regarding conservative treatment, intra-articular injections of hyaluronic acid (HA) can play a role in early symptomatic knee OA. MATERIALS AND METHODS: Between August 2015 and September 2015, sixty patients (32 males and 28 females) between 40 and 70 years old were randomly allocated into two groups: Half were treated with three weekly intra-articular injections of hyaluronic acid 1...
September 28, 2016: Musculoskeletal Surgery
https://www.readbyqxmd.com/read/27671822/boswellic-acids-and-their-role-in-chronic-inflammatory-diseases
#10
H P T Ammon
: Boswellic acids, which are pentacyclic triterpenes belong to the active pharmacological compounds of the oleogum resin of different Boswellia species. In the resin, more than 12 different boswellic acids have been identified but only KBA and AKBA received significant pharmacological interest. Biological Activity: In an extract of the resin of Boswellia species multiple factors are responsible for the final outcome of a therapeutic effect, be it synergistic or antagonistic. Moreover, the anti-inflammatory actions of BAs are caused by different mechanisms of action...
2016: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/27650786/chemical-composition-and-biological-activities-of-extracts-and-essential-oil-of-boswellia-dalzielii-leaves
#11
Midéko Justin Kohoude, Fernand Gbaguidi, Pierre Agbani, Marc-Abel Ayedoun, Sylvie Cazaux, Jalloul Bouajila
CONTEXT: Boswellia dalzielii Hutch. (Burseraceae) is an aromatic plant. The leaves are used for beverage flavouring. OBJECTIVE: This study investigates the chemical composition and biological activities of various extracts. MATERIALS AND METHODS: The essential oil was prepared via hydrodistillation. Identification and quantification were realized via GC-MS and GC-FID. Consecutive extractions (cyclohexane, dichloromethane, ethyl acetate and methanol) were carried out and various chemical groups (phenolics, flavonoids, tannins, antocyanins and sugar) were quantified...
September 21, 2016: Pharmaceutical Biology
https://www.readbyqxmd.com/read/27569885/chemical-composition-antiproliferative-antioxidant-and-antibacterial-activities-of-essential-oils-from-aromatic-plants-growing-in-sudan
#12
Sakina Yagi, Randa Babiker, Tzvetomira Tzanova, Herve Schohn
OBJECTIVE: To explore the potential of essential oil, as therapeutic molecule source, from olibanum of Boswellia papyrifera (Burseraceae), leafy stems of Cymbopogon schoenanthus (Poaceae) and Croton zambesicus (Euphorbiaceae) and rhizome of Cyperus rotundus (Cyperaceae) found in Sudan. Respective essential oil was evaluated for anti-proliferative, antibacterial and antioxidant activity. METHODS: Essential oils were extracted by hydrodistillation and then analysed by gas chromatography coupled to mass spectrometry (GC-MS)...
August 2016: Asian Pacific Journal of Tropical Medicine
https://www.readbyqxmd.com/read/27567921/the-effects-of-alpha-boswellic-acid-on-reelin-expression-and-tau-phosphorylation-in-human-astrocytes
#13
Esmat Fathi, Fatemeh Hedayati Katouli, Gholam Hossein Riazi, Marzieh Dehghan Shasaltaneh, Elham Parandavar, Samaneh Bayati, Ali Afrasiabi, Reza Nazari
Reelin is an extracellular glycoprotein which contributes to synaptic plasticity and function of memory in the adult brain. It has been indicated that the Reelin signaling cascade participates in Alzheimer's disease (AD). Besides the neurons, glial cells such as astrocytes also express Reelin protein. While functional loss of astrocytes has been reported to be associated with AD, dysfunction of astrocytic Reelin signaling pathway has not received much attention. Therefore, we investigated the effects of α-boswellic acid (ABA) as one of the major component of Boswellia serrata resin on primary fetal human astrocytes under a stress paradigm as a possible model for AD through study on Reelin cascade...
August 27, 2016: Neuromolecular Medicine
https://www.readbyqxmd.com/read/27545217/reversal-of-the-multidrug-resistance-of-human-ileocecal-adenocarcinoma-cells-by-acetyl-11-keto-%C3%AE-boswellic-acid-via-downregulation-of-p-glycoprotein-signals
#14
Xia Xue, Fang Chen, Anxin Liu, Deqing Sun, Jing Wu, Feng Kong, Yun Luan, Xianjun Qu, Rongmei Wang
Multidrug resistance (MDR) represents a clinical obstacle to cancer chemotherapy since it causes cancer recurrence and metastasis. Acetyl-11-keto-β-boswellic acid (AKBA), an active ingredient derived from the plant Boswellia serrata, has been found to inhibit the growth of a wide variety of tumor cells, including glioma, colorectal cancer, leukemia, human melanoma, hepatocellular carcinoma, and prostate cancer cells. However, the actions of AKBA in multidrug-resistant cancer cells have not been fully elucidated...
November 15, 2016: Bioscience Trends
https://www.readbyqxmd.com/read/27531547/cancer-chemopreventive-effects-of-boswellia-sacra-gum-resin-hydrodistillates-on-invasive-urothelial-cell-carcinoma-report-of-a-case
#15
Ding Xia, Weiwei Lou, Kar-Ming Fung, Cole L Wolley, Mahmoud M Suhail, Hsueh-Kung Lin
A 52-year-old Hispanic male presented with hematuria and was later diagnosed with a large invasive high-grade urothelial cell carcinoma (UCC) of the urinary bladder, but with ambiguous pT1/pT2 staging regarding musclaris propria invasion by UCC. The conventional treatment including radical cystoprostatectomy followed by neoadjuvant chemotherapy with or without radiation therapy was presented. The patient decided to delay the standard therapy until a later stage, but elected to go through transurethral resection of bladder tumor (TURBT) without Bacillus Calmette-Guérin instillation...
August 16, 2016: Integrative Cancer Therapies
https://www.readbyqxmd.com/read/27516696/the-efficacy-of-boswellia-serrata-gum-resin-for-control-of-lipid-profile-and-blood-glucose-in-diabetic-patients
#16
Saeed Mehrzadi, Bahreh Tavakolifar, Hasan Fallah Huseini, Seyed Hamdollah Mosavat, Mojtaba Heydari
BACKGROUND: Regarding preclinical evidence for antidiabetic effects of Boswellia serrata, we evaluated anti-hyperglycemic and lipid-lowering effects of Boswellia serrate gum resin in type 2 diabetic patients in a double-blind randomized placebo-control trial. METHODS: Fifty-six diabetic patients were randomly allocated to two groups to receive 250 mg of the Boswellia serrate gum resin or placebo twice daily for 8 weeks, in addition to their routine antidiabetic treatments...
May 2016: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/27515127/aqueous-and-ethanolic-extracts-of-boswellia-serrata-protect-against-focal-cerebral-ischemia-and-reperfusion-injury-in-rats
#17
Fatemeh Forouzanfar, Hossein Hosseinzadeh, Alireza Ebrahimzadeh Bideskan, Hamid R Sadeghnia
Oxidative stress and cell apoptosis play major roles in neuronal injury after ischemia-reperfusion (I-R) injury. Boswellia serrata is a medicinal plant with antioxidant properties. Acetyl-11-keto-β-boswellic acid (AKBA) is an active triterpenoid compound from B. serrate. In the current study, the neuroprotective effects of aqueous and ethanolic extracts of B. serrata (named ABS and EBS, respectively) and AKBA were investigated against middle cerebral artery occlusion-induced cerebral I-R injury in rats...
August 12, 2016: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/27494534/boswellia-serrata-protects-against-glutamate-induced-oxidative-stress-and-apoptosis-in-pc12-and-n2a-cells
#18
Arezoo Rajabian, Mohammad Taher Boroushaki, Parichehr Hayatdavoudi, Hamid Reza Sadeghnia
This study was designed to investigate whether the extract from Boswellia serrata oleo-gum resin (BSE) can protect against glutamate-induced oxidative damage and cytotoxicity in PC12 and N2a cell lines. Using a simple and reliable reverse-phase high-performance liquid chromatography (HPLC), the amount of 3-acetyl-11-keto-β-boswellic acid (AKBA) in the BSE was found to be 18.5% w/w. The results confirmed that BSE and AKBA, at concentrations as high as 100 μg/mL or 10 μM, respectively, caused no significant cytotoxicity or apoptotic cell death...
August 5, 2016: DNA and Cell Biology
https://www.readbyqxmd.com/read/27493682/simultaneous-quantification-of-triterpenoic-acids-by-high-performance-liquid-chromatography-method-in-the-extracts-of-gum-resin-of-boswellia-serrata-obtained-by-different-extraction-techniques
#19
Neha Sharma, Vikram Bhardwaj, Samar Singh, Sheikh Abid Ali, D K Gupta, Satya Paul, Naresh K Satti, Suresh Chandra, Mahendra K Verma
BACKGROUND: Boswellia serrata, also known as Indian frankincense is a commercially important medicinal plant which has been used for hundreds of years as an Ayurvedic medicine for the attempted treatment of arthritis. It contains naturally occurring triterpenoic acids, called as boswellic acids (BA's). RESULTS: A highly reproducible High performance liquid chromatography-ultraviolet diode array detection (HPLC-UV-DAD) method was developed for the simultaneous determination and quantitative analysis of eight major triterpenoic acids in Boswellia serrata gum resin obtained by different extraction techniques...
2016: Chemistry Central Journal
https://www.readbyqxmd.com/read/27460774/%C3%AE-boswellic-acid-a-bioactive-substance-used-in-food-supplements-inhibits-protein-synthesis-by-targeting-the-ribosomal-machinery
#20
A Casapullo, C Cassiano, A Capolupo, F Del Gaudio, R Esposito, A Tosco, R Riccio, M C Monti
The Boswellia gum resin extracts have been used in traditional medicines because of their remarkable anti-inflammatory properties. Nowadays, these extracts are on the market as food supplements. β-Boswellic acid (βBA) is one of the main pentacyclic triterpene components, among the family of BAs, of the Boswellia gum resins. BAs have been broadly studied and are well known for their wide anti-inflammatory and potential anticancer properties. In this paper, a mass spectrometry-based chemoproteomic approach has been applied to characterize the whole βBA interacting profile...
September 2016: Journal of Mass Spectrometry: JMS
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