Dmytro I Boiko, Hitesh Chopra, Muhammad Bilal, Pavlo V Kydon, Larysa O Herasymenko, Vadym O Rud, Lesia A Bodnar, Ganna Yu Vasylyeva, Rustam I Isakov, Liliia V Zhyvotovska, Aashna Mehta, Andrii M Skrypnikov
A molecular clock in the suprachiasmatic nucleus of the anterior hypothalamus, which is entrained by the dark-light cycle and controls the sleep-wake cycle, regulates circadian rhythms. The risk of developing mental disorders, such as schizophrenia, has long been linked to sleep abnormalities. Additionally, a common aspect of mental disorders is sleep disturbance, which has a direct impact on the intensity of the symptoms and the quality of life of the patient. This relationship can be explained by gene alterations such as CLOCK in schizophrenia which are also important components of the physiological circadian rhythm...
December 14, 2023: Schizophrenia Research