keyword
MENU ▼
Read by QxMD icon Read
search

Skeletons

keyword
https://www.readbyqxmd.com/read/29349779/skeletogenesis-in-the-persian-sturgeon-acipenser-persicus-and-its-correlation-with-gene-expression-of-vitamin-k-dependent-proteins-during-larval-development
#1
H Eshaghzadeh, A Akbarzadeh, M Yarmohammadi, E Gisbert
The present study describes morphological development of the skeleton in the Persian sturgeon Acipenser persicus and discusses the hypothesis that expression of genes encoding vitamin K-dependent proteins (VKDP) might be correlated with the mineralization of skeletal tissues during early development in sturgeons. Results showed that development of cartilage started just after hatching (mean ± S.D., 10·9 ± 0·7 mm in total length, LT ) in the head and notochord, whereas the first signs of mineralization occurred in the dentary and in the dermopalatine and palatopterygoid elements of the upper jaw, coinciding with the onset of exogenous feeding (20·1 ± 1·5 mm LT )...
January 18, 2018: Journal of Fish Biology
https://www.readbyqxmd.com/read/29347911/micrornas-associated-with-early-neural-crest-development-in-xenopus-laevis
#2
Nicole J Ward, Darrell Green, Janet Higgins, Tamas Dalmay, Andrea Münsterberg, Simon Moxon, Grant N Wheeler
BACKGROUND: The neural crest (NC) is a class of transitory stem cell-like cells unique to vertebrate embryos. NC cells arise within the dorsal neural tube where they undergo an epithelial to mesenchymal transition in order to migrate and differentiate throughout the developing embryo. The derivative cell types give rise to multiple tissues, including the craniofacial skeleton, peripheral nervous system and skin pigment cells. Several well-studied gene regulatory networks underpin NC development, which when disrupted can lead to various neurocristopathies such as craniofrontonasal dysplasia, DiGeorge syndrome and some forms of cancer...
January 18, 2018: BMC Genomics
https://www.readbyqxmd.com/read/29347488/numerical-calculation-on-a-two-step-subdiffusion-behavior-of-lateral-protein-movement-in-plasma-membranes
#3
Tomonari Sumi, Atsushi Okumoto, Hitoshi Goto, Hideo Sekino
A two-step subdiffusion behavior of lateral movement of transmembrane proteins in plasma membranes has been observed by using single-molecule experiments. A nested double-compartment model where large compartments are divided into several smaller ones has been proposed in order to explain this observation. These compartments are considered to be delimited by membrane-skeleton "fences" and membrane-protein "pickets" bound to the fences. We perform numerical simulations of a master equation using a simple two-dimensional lattice model to investigate the heterogeneous diffusion dynamics behavior of transmembrane proteins within plasma membranes...
October 2017: Physical Review. E
https://www.readbyqxmd.com/read/29346442/comparative-metabolic-ecology-of-tropical-herbivorous-echinoids-on-a-coral-reef
#4
Levi S Lewis, Jennifer E Smith, Yoan Eynaud
BACKGROUND: The metabolic rate of consumers is a key driver of ecosystem dynamics. On coral reefs, herbivorous echinoids consume fleshy algae, facilitating the growth of reef-building calcified organisms; however, little is known about differences among species in their metabolic and functional ecology. Here, we used log-linear (log-log) regression models to examine the allometric scaling of mass and routine metabolic rate for five common herbivorous echinoids on a Hawaiian coral reef: Echinothrix calamaris, E...
2018: PloS One
https://www.readbyqxmd.com/read/29346237/pediatric-pelvic-fractures-and-differences-compared-with-the-adult-population
#5
Carolina de la Calva, Nadia Jover, Jaime Alonso, Marta Salom
INTRODUCTION: Although pelvic fractures in children are rare, because of anatomical differences between an adult's skeleton and a child's skeleton, these lesions in the pediatric population have specific characteristics that need to be borne in mind when dealing with them. MATERIALS AND METHODS: A retrospective chart review was performed on the pelvic fractures in skeletally immature patients treated in our hospital in the last 20 years. RESULTS: Eighty-one pelvic fractures in children were treated between 1993 and 2013...
January 16, 2018: Pediatric Emergency Care
https://www.readbyqxmd.com/read/29345948/matched-coupling-of-propargylic-carbonates-with-cyclopropanols
#6
Penglin Wu, Minqiang Jia, Weilong Lin, Shengming Ma
The ring opening-coupling reaction of cyclopropanols with propargylic carbonates affording synthetically attractive allenyl ketones has been developed. The mechanism involves the ligand-exchange reaction of in situ formed allenyl palladium methoxide with cyclopropanols followed by carbon-carbon bond cleavage and reductive elimination. The reactions proceeded smoothly under mild reaction conditions with Pd(0)/XPhos catalysis in the absence of any external base and displayed a wide scope and application to a steroidal skeleton...
January 18, 2018: Organic Letters
https://www.readbyqxmd.com/read/29345917/anisotropic-assembly-of-ag52-and-ag76-nanoclusters
#7
Jia-Wei Liu, Lei Feng, Haifeng Su, Zhi Wang, Quan-Qin Zhao, Xingpo Wang, Chen-Ho Tung, Di Sun, Lan-Sun Zheng
Although there has been an upsurge of interest in anisotropic assembly of inorganic nanoparticles, atomically precise self-assembly of anisotropic (nonspherical) high-nuclearity metal clusters is extremely rare. Herein, we presented two novel silver nanoclusters, Ag52 (SD/Ag23) and Ag76 (SD/Ag24), which are interiorly templated by five MoO42- and a pair of Mo6O228- anions, respectively, and co-protected by bridging RSH and terminal diphosphine ligands exteriorly. Regiospe-cific distribution diphosphine ligands on the surface and the arrangement of multiple molybdate templates within the nanoclusters synergetically tailor their shapes to anisotropic oblate spheroid and elongated rod, respectively, as opposed to isotropic nanospheres...
January 18, 2018: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/29345718/evaluation-of-the-morphological-characteristic-and-sex-differences-of-sternum-by-multi-detector-computed-tomography
#8
Sibel Ateşoğlu, Mustafa Deniz, Ayşe İmge Uslu
BACKGROUND: Sternum is one of the skeleton parts which have frequently congenital anomalies and variations are commonly used by researchers in determining sex. We evaluated the morphological characteristics and sex-related changes of the sternum in adult individuals using multidetector CT in our study. MATERIALS AND METHODS: 200 adults (103 female and 97 male) aged between 18-87 years were evaluated. Utilizing the morphological characteristics of the sternum based on the multi-slice images; length, width and the thickness of Manubrium, length, width and the thickness of Corpus Sterni, total length of Sternum, Sternal angle, Sternal index, length of the xiphoid process, the thickness of xiphoid process, the number of indents of xiphoid process were measured and a total of 20 parameters were evaluated by adding age, height and weight to these variables...
January 18, 2018: Folia Morphologica (Warsz)
https://www.readbyqxmd.com/read/29345474/total-synthesis-of-antiproliferative-parvifloron-f
#9
Yohei Saito, Masuo Goto, Kyoko Nakagawa-Goto
The first total synthesis of parvifloron F, a bioactive highly oxidized abietane diterpene, was achieved. The abietane skeleton was constructed by Lewis acid promoted cyclization. Preliminary structure-activity relationship correlations were established for the synthetic intermediates against human tumor cell lines. Certain compounds showed unique selective antiproliferative activity against triple-negative breast cancer. The oxidation level of the abietane ring affected the selectivity.
January 18, 2018: Organic Letters
https://www.readbyqxmd.com/read/29345463/-%C3%A2-sativamides-a-and-b-two-pairs-of-racemic-nor-lignanamide-enantiomers-from-the-fruits-of-cannabis-sativa-hemp-seed
#10
Guo-Yuan Zhu, Ji Yang, Xiao-Jun Yao, Xing Yang, Jing Fu, Xin Liu, Li-Ping Bai, Liang Liu, Zhi-Hong Jiang
(±)-Sativamides A (1) and B (2), two pairs of nor-lignanamide enantiomers featuring a unique benzo-angular triquinane skeleton, were isolated from the fruits of Cannabis sativa (hemp seed). Their structures were elucidated by detailed spectroscopic analysis and ECD calculations. The resolution of (+)- and (-)-sativamides A and B were achieved by chiral HPLC. Pretreatment of neuroblastoma cells with 1 and 2 significantly reduced the endoplasmic reticulum (ER) stress-induced cytotoxicity.
January 18, 2018: Journal of Organic Chemistry
https://www.readbyqxmd.com/read/29345302/body-mass-prediction-from-femoral-volume-and-sixteen-other-femoral-variables-in-the-elderly-bmi-and-adipose-tissue-effects
#11
Tony Chevalier, Jan Pieter Clarys, Philippe Lefèvre, Jean-Pol Beauthier, Stéphane Louryan, Erik Cattrysse
OBJECTIVES: The frequently used prediction equations of body mass do not seem appropriate for elderly individuals. Here, we establish the relationship between femoral dimensions and known body mass in elderly individuals in order to develop prediction formulas and identify the factors affecting their accuracy. MATERIALS AND METHODS: The body mass linear least-squares regression is based on 17 femoral dimensions, including femoral volume, and 66 individuals. Body proportion and composition effects on accuracy are analyzed by means of the body mass index (BMI) and on a subset sample (n = 25), by means of the masses of adipose, bone and muscle tissues...
January 18, 2018: American Journal of Physical Anthropology
https://www.readbyqxmd.com/read/29344958/protective-effects-of-new-antioxidant-compositions-of-4-methylcoumarins-and-related-compounds-with-dl-%C3%AE-tocopherol-and-l-ascorbic-acid
#12
Vessela D Kancheva, Adriana K Slavova-Kazakova, Silvia E Angelova, Prashant Kumar, Shashwat Malhotra, Brajendra K Singh, Luciano Saso, Ashok K Prasad, Virinder S Parmar
BACKGROUND: Coumarin derivatives possess a wide range of biological activities. By functionalization of the parent coumarin skeleton that has neither antioxidant nor biological activity a series of new bio-antioxidants has been designed. RESULTS: New antioxidant compositions (equimolar binary and ternary mixtures) of eight 4-methylcoumarins and three related compounds have been tested and different effects between the individual components have been observed: positive effect (synergism), summary effect (additivism) and negative effect (antagonism)...
January 18, 2018: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/29344941/systemic-patterns-of-trabecular-bone-across-the-human-and-chimpanzee-skeleton
#13
Zewdi J Tsegai, Matthew M Skinner, Dieter H Pahr, Jean-Jacques Hublin, Tracy L Kivell
Aspects of trabecular bone architecture are thought to reflect regional loading of the skeleton, and thus differ between primate taxa with different locomotor and postural modes. However, there are several systemic factors that affect bone structure that could contribute to, or be the primary factor determining, interspecific differences in bone structure. These systemic factors include differences in genetic regulation, sensitivity to loading, hormone levels, diet, and activity levels. Improved understanding of inter-/intraspecific variability, and variability across the skeleton of an individual, is required to interpret properly potential functional signals present within trabecular structure...
January 18, 2018: Journal of Anatomy
https://www.readbyqxmd.com/read/29344931/relationship-between-body-mass-lean-mass-fat-mass-and-limb-bone-cross-sectional-geometry-implications-for-estimating-body-mass-and-physique-from-the-skeleton
#14
Emma Pomeroy, Alison Macintosh, Jonathan C K Wells, Tim J Cole, Jay T Stock
OBJECTIVES: Estimating body mass from skeletal dimensions is widely practiced, but methods for estimating its components (lean and fat mass) are poorly developed. The ability to estimate these characteristics would offer new insights into the evolution of body composition and its variation relative to past and present health. This study investigates the potential of long bone cross-sectional properties as predictors of body, lean, and fat mass. MATERIALS AND METHODS: Humerus, femur and tibia midshaft cross-sectional properties were measured by peripheral quantitative computed tomography in sample of young adult women (n = 105) characterized by a range of activity levels...
January 18, 2018: American Journal of Physical Anthropology
https://www.readbyqxmd.com/read/29343614/suppressor-of-cytokine-signaling-2-socs2-deletion-protects-bone-health-of-mice-with-dss-induced-inflammatory-bowel-disease
#15
Ross Dobie, Vicky E MacRae, Chloe Pass, Elspeth M Milne, S Faisal Ahmed, Colin Farquharson
Individuals with inflammatory bowel disease (IBD) often present with poor bone health. The development of targeted therapies for this bone loss requires a fuller understanding of the underlying cellular mechanisms. Although bone loss in IBD is multifactorial, the altered sensitivity and secretion of growth hormone (GH) and insulin-like growth factor-1 (IGF-1) in IBD is understood to be a critical contributing mechanism. The expression of suppressor of cytokine signaling 2 (SOCS2), a well-established negative regulator of GH signaling, is stimulated by proinflammatory cytokines...
January 17, 2018: Disease Models & Mechanisms
https://www.readbyqxmd.com/read/29343600/rapid-phenotypic-evolution-following-shifts-in-life-cycle-complexity
#16
Ronald M Bonett, John G Phillips, Nicholus M Ledbetter, Samuel D Martin, Luke Lehman
Life cycle strategies have evolved extensively throughout the history of metazoans. The expression of disparate life stages within a single ontogeny can present conflicts to trait evolution, and therefore may have played a major role in shaping metazoan forms. However, few studies have examined the consequences of adding or subtracting life stages on patterns of trait evolution. By analysing trait evolution in a clade of closely related salamander lineages we show that shifts in the number of life cycle stages are associated with rapid phenotypic evolution...
January 31, 2018: Proceedings. Biological Sciences
https://www.readbyqxmd.com/read/29342858/novel-fiber-optic-ring-acoustic-emission-sensor
#17
Peng Wei, Xiaole Han, Dong Xia, Taolin Liu, Hao Lang
Acoustic emission technology has been applied to many fields for many years. However, the conventional piezoelectric acoustic emission sensors cannot be used in extreme environments, such as those with heavy electromagnetic interference, high pressure, or strong corrosion. In this paper, a novel fiber-optic ring acoustic emission sensor is proposed. The sensor exhibits high sensitivity, anti-electromagnetic interference, and corrosion resistance. First, the principle of a novel fiber-optic ring sensor is introduced...
January 13, 2018: Sensors
https://www.readbyqxmd.com/read/29341382/synthesis-crystal-analysis-and-optoelectronic-properties-of-diazole-functionalized-acenes-and-azaacenes
#18
Jinchong Xiao, Huahang Pan, Tingting Song, Xiaomeng Yin, Pengcheng Jin
Doping heteroatoms into the skeletons of parent acenes can provide more chances to construct novel thermally and photo-stable organic π-conjugated semiconductors. Herein, a family of diazole-decorated acenes (APyS and APySe) and azaacenes (PyP, PyTh, PyPy, PyPh and PyAP) have been successfully synthesized through the classical reactions. Single crystal X-ray analyses showed that these as-formed diazole-modified derivatives adopted twisted topology configuration, whereas the azaacenes display reclining-chair architectures, besides twisted structure...
January 17, 2018: Chemistry: a European Journal
https://www.readbyqxmd.com/read/29340996/recent-advances-in-the-development-of-polycyclic-skeletons-via-ugi-reaction-cascades
#19
REVIEW
Jie Lei, Jiang-Ping Meng, Dian-Yong Tang, Brendan Frett, Zhong-Zhu Chen, Zhi-Gang Xu
Isocyanide-based multicomponent reactions are among the most powerful synthetic tools available. Particularly, the isocyanide-based Ugi reaction can allow rapid preparation of [Formula: see text]-aminoacyl amide derivatives and polyazaheterocycles with extensive pharmaceutical applications. Moreover, bridged polyazaheterocycles, including one or more quaternary carbon centers, can be constructed via the Ugi cascade reaction in a few steps. This review will emphasize synthesis and bioactivities of bridged compounds with quaternary centers constructed through Ugi cascade reactions...
January 16, 2018: Molecular Diversity
https://www.readbyqxmd.com/read/29340980/facile-synthesis-of-chitosan-capped-mesoporous-silica-nanoparticles-a-ph-responsive-smart-delivery-platform-for-raloxifene-hydrochloride
#20
Priya V Shah, Sadhana J Rajput
An encapsulation of model drug raloxifene hydrochloride (RAL) inside the chitosan decorated pH responsive mesoporous system has a greater potential for accumulating in the tumor cells. The present study involves synthesis of surface modified mesoporous silica nanoparticles (MSN) with the aim of achieving pH sensitive drug delivery system. A silanol skeleton of MSN has been productively modified to amine intermediate which served as a firm platform to adapt chitosan grafted assembly and systematically evaluated...
January 16, 2018: AAPS PharmSciTech
keyword
keyword
40371
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"