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https://www.readbyqxmd.com/read/29679271/concurrent-reduction-adsorption-of-chromium-using-m-phenylenediamine-modified-magnetic-chitosan-kinetics-isotherm-and-mechanism
#1
Zhonghao Wan, Meng Li, Qian Zhang, Zixi Fan, Francis Verpoort
Magnetic chitosan particles (MCS) were chemically grafted by m-phenylenediamine (mPD) forming a distinctive shell layer with abundant nitrogenous functional groups and used as an adsorbent for the effective removal of Cr(VI) from aqueous solution. By interaction among functional groups in the facile oxidative polymerization process, the grafting of mPD and its polymers on MCS surface was innovatively realized. Through Fourier-transformed infrared spectroscopy, energy dispersive spectrometer, X-ray photoelectron spectroscopy, etc...
April 20, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29668421/factors-associated-with-unplanned-early-discharges-from-a-dual-diagnosis-inpatient-detoxification-unit-in-israel
#2
Menachem M Sofer, Alexander Kaptsan, Jonathan Anson
OBJECTIVES: Currently, Israel has a single governmental inpatient dual diagnosis detoxification unit. We provide a cross-section of patient profiles in this unit, as well as explore possible associations between clinical/demographic factors, and the unplanned early discharge of patients from the unit, aiming at improving rehabilitation success rates. METHODS: In this retrospective study, medical records of all patients admitted to the unit between January 1st 2012 and July 1st 2013 were examined (N = 323)...
April 18, 2018: Journal of Dual Diagnosis
https://www.readbyqxmd.com/read/29630078/applications-of-zeolites-in-biotechnology-and-medicine-a-review
#3
REVIEW
Lucie Bacakova, Marta Vandrovcova, Ivana Kopova, Ivan Jirka
Zeolites are microporous tectosilicates of natural or synthetic origin, which have been extensively used in various technological applications, e.g. as catalysts and as molecular sieves, for separating and sorting various molecules, for water and air purification, including removal of radioactive contaminants, for harvesting waste heat and solar heat energy, for adsorption refrigeration, as detergents, etc. These applications of zeolites were typically related with their porous character, their high adsorption capacity, and their ion exchange properties...
April 9, 2018: Biomaterials Science
https://www.readbyqxmd.com/read/29524737/heroic-journeys-through-sobriety-how-temporary-alcohol-abstinence-campaigns-portray-participant-experiences
#4
Ashlea Bartram, Scott Hanson-Easey, Jaklin Eliott
BACKGROUND: In Australia, recent years have seen a rise in the popularity of temporary abstinence campaigns, in which people pledge to abstain from alcohol for a month while raising funds for charity. In addition to their fundraising aims, such initiatives have been viewed as tools for broader behavioural and cultural change around alcohol, encouraging participants to reflect on their drinking and make longer-term changes to their behaviour. The extent to which these initiatives promote enduring change may depend on how they portray the experience of temporarily abstaining from alcohol, and how they position participants...
March 7, 2018: International Journal on Drug Policy
https://www.readbyqxmd.com/read/29484776/the-effects-of-fresh-detox-juices-on-color-stability-and-roughness-of-resin-based-composites
#5
İhsan Yikilgan, Sinem Akgul, Ahmet Hazar, Cemile Kedıcı Alp, Serdar Baglar, Oya Bala
PURPOSE: To evaluate the effects of three fresh detox juices, including an orange, green, and red beverage, on the color stability and surface roughness of three anterior esthetic resin-based composites (RBCs). MATERIALS AND METHODS: Disk-shaped specimens were prepared with three different esthetic RBCs (Amaris, G-aenial Anterior, Clearfil Majesty ES-2) according to the manufacturers' instructions. Forty specimens were prepared for each RBC, and all specimens were stored in artificial saliva at 37°C for 24 hours...
February 27, 2018: Journal of Prosthodontics: Official Journal of the American College of Prosthodontists
https://www.readbyqxmd.com/read/29482460/pain-related-anxiety-and-opioid-misuse-in-a-racially-ethnically-diverse-young-adult-sample-with-moderate-severe-pain
#6
Andrew H Rogers, Jafar Bakhshaie, Hantin Lam, Kirsten J Langdon, Joseph W Ditre, Michael J Zvolensky
Pain problems are of significant public health concern, and with opioid-related problems and death due to overdose at an all-time high, there is significant public health importance to identify risk factors that link instances of pain to opioid misuse among persons with pain whether or not they have been prescribed opioids for pain management. Severe pain and pain-related problems have been associated with increased risk for opioid misuse, and recent research indicates that pain-related anxiety (worry about the negative consequences of pain) may contribute to a more debilitating pain experience...
February 26, 2018: Cognitive Behaviour Therapy
https://www.readbyqxmd.com/read/29460622/influence-of-ugt2b10-genotype-on-urinary-excretion-of-nnal-n-glucuronide-by-african-american-smokers
#7
Sharon Elizabeth Murphy, Linda von Weymarn, Marc Parenteau, Irina Stepanov, Maarit Tiirikainen, Loic LeMarchand, Sungshim L Park
At similar smoking levels African American's lung cancer risk is as much as twice that of whites. We hypothesized that racial/ethnic differences in UDP-glucuronosyltransferase (UGT)-catalyzed glucuronidation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL), a detoxication pathway for the tobacco-specific lung carcinogen NNK (4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone), may contribute to this variable risk. UGT2B10 catalyzes NNAL N-glucuronidation and a UGT2B10 splice variant is common among African Americans...
February 20, 2018: Chemical Research in Toxicology
https://www.readbyqxmd.com/read/29374135/sulfenylation-of-human-liver-and-kidney-microsomal-cytochromes-p450-and-other-drug-metabolizing-enzymes-as-a-response-to-redox-alteration
#8
Matt Albertolle, Thanh T N Phan, Ambra Pozzi, F Peter Guengerich
The lumen of the endoplasmic reticulum (ER) provides an oxidizing environment to aid in the formation of disulfide bonds, which is tightly regulated by both antioxidant proteins and small molecules. On the cytoplasmic side of the ER, cytochrome P450 (P450) proteins have been identified as a superfamily of enzymes that are important in the formation of endogenous chemicals as well as in the detoxication of xenobiotics. Our previous report described oxidative inhibition of P450 Family 4 enzymes via oxidation of the heme-thiolate cysteine to a sulfenic acid (-SOH) (Albertolle, M...
January 26, 2018: Molecular & Cellular Proteomics: MCP
https://www.readbyqxmd.com/read/29366871/cytochrome-p450-1a1-cyp1a1-protects-against-nonalcoholic-fatty-liver-disease-caused-by-western-diet-containing-benzo-a-pyrene-in-mice
#9
Shigeyuki Uno, Daniel W Nebert, Makoto Makishima
The Western diet contributes to nonalcoholic fatty liver disease (NAFLD) pathogenesis. Benzo[a]pyrene (BaP), a prototypical environmental pollutant produced by combustion processes, is present in charcoal-grilled meat. Cytochrome P450 1A1 (CYP1A1) metabolizes BaP, resulting in either detoxication or metabolic activation in a context-dependent manner. To elucidate a role of CYP1A1-BaP in NAFLD pathogenesis, we compared the effects of a Western diet, with or without oral BaP treatment, on the development of NAFLD in Cyp1a1(-/-) mice versus wild-type mice...
March 2018: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/29362220/integration-of-oncogenes-via-sleeping-beauty-as-a-mouse-model-of-hpv16-oral-tumors-and-immunologic-control
#10
Yi-Hsin Lin, Ming-Chieh Yang, Ssu-Hsueh Tseng, Rosie Jiang, Andrew Yang, Emily Farmer, Shiwen Peng, Talia Henkle, Yung-Nien Chang, Chien-Fu Hung, T-C Wu
Human papillomavirus type 16 (HPV16) is the etiologic factor for cervical cancer and a subset of oropharyngeal cancers. Although several prophylactic HPV vaccines are available, no effective therapeutic strategies to control active HPV diseases exist. Tumor implantation models are traditionally used to study HPV-associated buccal tumors. However, they fail to address precancerous phases of disease progression and display tumor microenvironments distinct from those observed in patients. Previously, K14-E6/E7 transgenic mouse models have been used to generate spontaneous tumors...
January 23, 2018: Cancer Immunology Research
https://www.readbyqxmd.com/read/29325416/igy-reduces-afb-1-induced-cytotoxicity-cellular-dysfunction-and-genotoxicity-in-human-l-02-hepatocytes-and-swan-71-trophoblasts
#11
Taotao Qiu, Xing Shen, Zhen Tian, Riming Huang, Xiangmei Li, Juan Wang, Rong Wang, Yuanming Sun, Yiguo Jiang, Hongtao Lei, Huidong Zhang
Aflatoxin B1 (AFB1 ) causes hepatotoxic, genotoxic, and immunotoxic effects in a variety of species. Although various neutralizing agents of AFB1 toxicity have been studied, the egg yolk immunoglobulin (IgY) detoxification of small molecular toxins and the mechanisms underlying such effects have not yet been reported. In this investigation, anti-AFB1 IgY against AFB1 was successfully raised, and a competitive indirect enzyme-linked immunosorbent assay was established with a sensitive half-maximal inhibitory concentration (IC50, 2...
February 14, 2018: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/29309501/ectopic-expression-of-bdcipk31-confers-enhanced-low-temperature-tolerance-in-transgenic-tobacco-plants
#12
Qingchen Luo, Qiuhui Wei, Ruibin Wang, Yang Zhang, Fan Zhang, Yuan He, Guangxiao Yang, Guangyuan He
Calcineurin B-like protein (CBL), the Ca2+ sensor, and its interacting protein kinases (CIPKs) play essential roles in plants' response to stress. However, few studies have focused on the functions of CIPKs in low-temperature response. In the present study, BdCIPK31, a cold-responsive CIPK in Brachypodium distachyon, was found to participate in low-temperature response. Ectopic expression of BdCIPK31 conferred cold tolerance in transgenic tobaccos. Further analyses indicated that expression of BdCIPK31 improved ROS detoxication and omsoprotectant biosynthesis in transgenic plants under low-temperature treatment, suggesting that the BdCIPK31 functions positively in plant adaption to the cold-induced oxidative and osmotic stresses...
February 1, 2018: Acta Biochimica et Biophysica Sinica
https://www.readbyqxmd.com/read/29306936/remote-healing-of-bipolar-disorder-eating-disorder-not-otherwise-specified-posttraumatic-stress-disorder-fibromyalgia-and-irritable-bowel-syndrome-through-lifestyle-change
#13
Kelly Brogan
This case report illustrates the relationship between gut, hormonal, and brain function in that dietary change, mindfulness interventions, and detoxification led to resolution of disabling psychiatric symptoms. In this case, a single Caucasian female resolved her symptoms of bipolar disorder (BD) including psychotic features and suicidality, posttraumatic stress disorder symptoms from childhood torture, disordered eating, fibromyalgia, and irritable bowel syndrome through lifestyle interventions. This patient survived a severe trauma history only to develop alcohol dependence, disordered eating, and depressive symptoms, which were treated with a polypharmaceutical psychiatric approach...
October 2017: Advances in Mind-body Medicine
https://www.readbyqxmd.com/read/29302560/benzodiazepine-maintenance-for-alcohol-dependence-a-case-series
#14
Shivanand Kattimani, Balaji Bharadwaj, Anand Babu Arun
Alcohol addiction is a chronic relapsing syndrome. Benzodiazepines remain as the mainstay for detoxification, taking care of the acute withdrawal syndrome. There is fear of dependence and abuse of benzodiazepines on prolonged use. Here, we selectively interviewed ten cases who were on longer duration of benzodiazepines to elicit their potential perceived benefits, attitudes, and any adverse effect. Three patients experienced adverse effects. None of them had features of benzodiazepine dependence. We opine that in select cases, benzodiazepine use should persist beyond detox period, and its benefits continue beyond the acute withdrawal phase while monitoring their safety/adverse effects...
April 2017: Journal of Family Medicine and Primary Care
https://www.readbyqxmd.com/read/29290059/does-heavy-metal-exposure-affect-the-condition-of-whitethroat-sylvia-communis-nestlings
#15
Katarzyna Turzańska-Pietras, Justyna Chachulska, Ludmiła Polechońska, Marta Borowiec
Anthropogenic pollution results in high concentrations of heavy metals in the environment. Due to their persistence and a high potential for bioaccumulation, metals are a real threat for birds breeding in industrial areas. The aim of the present study has been to explore the contents of heavy metals (arsenic As, cadmium Cd, chromium Cr, copper Cu, iron Fe, nickel Ni, lead Pb and zinc Zn) in the excreta of Whitethroat (Sylvia communis) nestlings living in polluted environment and to investigate the relationship between these contents and the nestlings' condition...
March 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29290030/use-of-zeolite-to-neutralise-nickel-in-a-soil-environment
#16
Edyta Boros-Lajszner, Jadwiga Wyszkowska, Jan Kucharski
Nickel is a heavy metal which is a stable soil pollutant which is difficult to remediate. An attempt to reduce its impact on the environment can be made by changing its solubility. The right level of hydrogen ions and the content of mineral and organic colloids are crucial in this regard. Therefore, methods to neutralise heavy metals in soil are sought. There are no reports in the literature on the possibility of using minerals in the detoxication of a soil environment contaminated with metals. It is important to fill the gap in research on the effect of zeolites on the microbiological, biochemical and physicochemical properties of soils under pressure from heavy metals...
December 30, 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/29281794/reduction-and-scavenging-of-chemically-reactive-drug-metabolites-by-nad-p-h-quinone-oxidoreductase-1-and-nrh-quinone-oxidoreductase-2-and-variability-in-hepatic-concentrations
#17
Shalenie P den Braver-Sewradj, Michiel W den Braver, Robin M Toorneman, Stephanie van Leeuwen, Yongjie Zhang, Stefan J Dekker, Nico P E Vermeulen, Jan N M Commandeur, J Chris Vos
Detoxicating enzymes NAD(P)H:quinone oxidoreductase 1 (NQO1) and NRH:quinone oxidoreductase 2 (NQO2) catalyze the two-electron reduction of quinone-like compounds. The protective role of the polymorphic NQO1 and NQO2 enzymes is especially of interest in the liver as the major site of drug bioactivation to chemically reactive drug metabolites. In the current study, we quantified the concentrations of NQO1 and NQO2 in 20 human liver donors and NQO1 and NQO2 activities with quinone-like drug metabolites. Hepatic NQO1 concentrations ranged from 8 to 213 nM...
February 19, 2018: Chemical Research in Toxicology
https://www.readbyqxmd.com/read/29258441/comparative-transcriptome-analysis-of-glyphodes-pyloalis-walker-lepidoptera-pyralidae-reveals-novel-insights-into-heat-stress-tolerance-in-insects
#18
Yuncai Liu, Hang Su, Rongqiao Li, Xiaotong Li, Yusong Xu, Xiangping Dai, Yanyan Zhou, Huabing Wang
BACKGROUND: Heat tolerance is a key parameter that affects insect distribution and abundance. Glyphodes pyloalis Walker (Lepidoptera: Pyralidae) is a devastating pest of mulberry in the main mulberry-growing regions and can cause tremendous losses to sericulture by directly feeding on mulberry leaves and transmitting viruses to Bombyx mori. Moreover, G. pyloalis shows a prominent capacity for adaptation to daily and seasonal temperature fluctuations and can survive several hours under high temperature...
December 19, 2017: BMC Genomics
https://www.readbyqxmd.com/read/29235299/-prescription-regularity-of-famous-veteran-traditional-chinese-medicine-doctor-yu-guoyou-for-treating-gastrointestinal-failure-based-ondata-mining
#19
Qing Wang, Yi-Lian Chen, Guo-Lin Wu, Fu-Lin Xiong, Guo-You Yu
Gastrointestinal failure is a kind of severe systemic inflammatory response, and often complicated with multiple organ dysfunction syndrome. Integrated traditional Chinese and Western medicine have a better curative effect in treating it. This study collected the famous veteran TCM physician Yu Guoyou's 175 prescriptions for treating 89 cases of gastrointestinal failure, calculated the frequency of traditional Chinese medicines and their categories, and analyzed the medication regularity with system clustering method, so as to summarize Yu's frequently used drugs and prescriptions...
October 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29215843/-influence-of-partial-hepatectomie-on-ammoniumdetoxications-function-of-liver-at-chronic-tetrachlorcarbon-hepatitis
#20
P N Savilov
The purpose. To study the effect of partial hepatectomy (PH) on the main ways of ammonia detoxication in the liver (synthesis of urea and glutamine) in chronic tetrachlorcarbon (CCl4) hepatitis. Methods. The experiments were performed on 165 white outbred rats (females) weighing 180-220 g Chronic CCl4-hepatitis was reproduced by subcutaneous injection of 50% CCl4 solution in olive oil (0.1 ml/100g of body weight,65 days, through the day with two two-week breaks between 6-7 and 13-14 injections). PH conducted electrocautery, removing part of the left lobe of the liver (15-20% by weight of the body) to 65th (and last) day of the introduction of the CCl4...
April 2017: Patologicheskaia Fiziologiia i èksperimental'naia Terapiia
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