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https://www.readbyqxmd.com/read/28646811/alternative-therapy-for-patients-with-obstructive-sleep-apnea-hypopnea-syndrome-a-1-year-single-blind-randomized-trial-of-tui-na
#1
Cheng-Nan Lu, Michael Friedman, Hsin-Ching Lin, Kuo-Wei Bi, Tun-Pin Hsueh, Hsueh-Wen Chang, Mao-Chang Su, Meng-Chih Lin
Context • Obstructive sleep apnea/hypopnea syndrome (OSAHS) is among the most prevalent of sleep-related breathing disorders. No long-term follow-up studies have documented the continued success of lifestyle changes in treatment; oral appliances have an approximate 50% success rate; compliance with continuous positive airway pressure is poor, ranging from 50% to 89%; and the success rate of upper-airway surgery is only 66.4%. Therefore, some OSAHS patients seek alternative treatments. Objectives • The study intended to examine the efficacy of traditional Chinese therapeutic massage (tui na) for patients with OSAHS...
July 2017: Alternative Therapies in Health and Medicine
https://www.readbyqxmd.com/read/28633724/change-in-end-expiratory-lung-volume-during-sleep-in-patients-at-risk-for-obstructive-sleep-apnea
#2
Patrick Koo, Eric J Gartman, Jigme M Sethi, Eyad Kawar, F Dennis McCool
STUDY OBJECTIVES: As lung volume decreases radial traction on the upper airway is reduced, making it more collapsible. The purpose of this study was to measure change in end-expiratory lung volume (EELV) following sleep onset and to evaluate the relationship between change in EELV and sleep-disordered breathing. METHODS: Twenty subjects underwent overnight polysomnography, of whom 14 (70%) had obstructive sleep apnea (OSA). Change in EELV was measured throughout the night using magnetometry...
June 16, 2017: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/28631914/-impact-of-cpap-therapy-on-erectile-function-during-sleep-and-testosterone-level-in-men-with-sleep-apnea-syndrome
#3
I M Madaeva, O N Berdina, N V Semenova, V V Madaev, I N Gutnik, L I Kolesnikova
The article presents the results of a polysomnographic study with simultaneous monitoring spontaneous nocturnal erections - Nocturnal Penile Tumescences (NPT) in 69 men with age-related androgen deficiency (AAD). Of these, 45 patients were diagnosed with obstructive sleep apnea syndrome (OSAS). In 34 of the 45 patients with OSAS, regimens of non-invasive ventilation with positive-positive airway pressure (CPAP) were selected. Titration was carried out using automatic CPAP-devices for 2 months. The control group (n=24) comprised men with AAD, matched by the "copy-pair" type without clinical manifestations of respiratory disturbances during sleep...
June 2017: Urologii︠a︡
https://www.readbyqxmd.com/read/28629917/personalized-management-approach-for-obstructive-sleep-apnea
#4
REVIEW
Jayne C Carberry, Jason Amatoury, Danny J Eckert
Obstructive sleep apnea (OSA) is a heterogeneous disorder. If left untreated, OSA has major health, safety and economic consequences. In addition to varying levels of impairment in pharyngeal anatomy (narrow/collapsible airway), non-anatomical 'phenotypic traits' are also important contributors to OSA for most patients. However, the majority of existing therapies only target the anatomical cause (e.g. continuous positive airway pressure [CPAP], oral appliances, weight loss, positional therapy, and upper airway surgery)...
June 16, 2017: Chest
https://www.readbyqxmd.com/read/28623043/nasal-airway-evaluation-in-obstructive-sleep-apnoea-patients-volumetric-tomography-and-endoscopic-findings
#5
M M Rodrigues, M F R Gabrielli, O A Garcia Junior, V A Pereira Filho, L A Passeri
Obstructive sleep apnoea (OSA) results from the recurrent collapse of the upper airway during sleep. Nasal abnormalities influence the stability of the pharynx. The aim of this study was to evaluate the volumetric and anatomical changes of the nasal cavity in patients with OSA. The Nasal Obstruction Symptom Evaluation (NOSE) scale was used to grade nasal obstruction. Sleep-related breathing disorders were evaluated by polysomnography. The nasal airway volume was obtained from computed tomography scans through volumetric reconstruction of the nasal airway...
June 13, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28620266/mechanistic-evaluation-of-the-impact-of-smoking-and-chronic-obstructive-pulmonary-disease-on-the-nasal-epithelium
#6
Marja Talikka, Florian Martin, Alain Sewer, Grégory Vuillaume, Patrice Leroy, Karsta Luettich, Nveed Chaudhary, Michael J Peck, Manuel C Peitsch, Julia Hoeng
Chronic obstructive pulmonary disease (COPD) is one of the major causes of chronic morbidity and mortality worldwide. The development of markers of COPD onset is hampered by the lack of accessibility to the primary target tissue, and there is a need to consider other sample sources as surrogates for biomarker research. Airborne toxicants pass through the nasal epithelium before reaching the lower airways, and the similarity with bronchial histology makes it an attractive surrogate for lower airways. In this work, we describe the transcriptomics findings from the nasal epithelia of subjects enrolled in a clinical study focusing on the identification of COPD biomarkers...
2017: Clinical Medicine Insights. Circulatory, Respiratory and Pulmonary Medicine
https://www.readbyqxmd.com/read/28620058/intermittent-hypercapnic-hypoxia-during-sleep-does-not-induce-ventilatory-long-term-facilitation-in-healthy-males
#7
Naomi Louise Deacon, Doug R McEvoy, Daniel L Stadler, Peter G Catcheside
Intermittent hypoxia induced ventilatory neuroplasticity is likely important in obstructive sleep apnea pathophysiology. Although concomitant CO2 levels and arousal state critically influence neuroplastic effects of intermittent hypoxia, no studies have investigated intermittent hypercapnic hypoxia effects during sleep in humans. Thus, the purpose of this study was to investigate if intermittent hypercapnic hypoxia during sleep induces neuroplasticity (ventilatory long-term facilitation and increased chemoreflex responsiveness) in humans...
June 15, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28619065/open-issues-in-mucopolysaccharidosis-type-i-hurler
#8
REVIEW
Rossella Parini, Federica Deodato, Maja Di Rocco, Edoardo Lanino, Franco Locatelli, Chiara Messina, Attilio Rovelli, Maurizio Scarpa
Mucopolysaccharidosis I-Hurler (MPS I-H) is the most severe form of a metabolic genetic disease caused by mutations of IDUA gene encoding the lysosomal α-L-iduronidase enzyme. MPS I-H is a rare, life-threatening disease, evolving in multisystem morbidity including progressive neurological disease, upper airway obstruction, skeletal deformity and cardiomyopathy. Allogeneic hematopoietic stem cell transplantation (HSCT) is currently the gold standard for the treatment of MPS I-H in patients diagnosed and treated before 2-2...
June 15, 2017: Orphanet Journal of Rare Diseases
https://www.readbyqxmd.com/read/28614224/a-case-report-of-local-treatment-of-inoperable-squamous-cell-lung-carcinoma-with-convex-probe-endobronchial-ultrasound-guided-intratumoral-injection-of-cisplatin-in-a-patient-with-severe-copd
#9
Xiaochen Li, Xiansheng Liu, Xiaoling Rao, Jianping Zhao, Yongjian Xu, Min Xie
RATIONALE: Endobronchial ultrasound as a powerful diagnostic technology can also be used to perform intratumoral chemotherapy for extraluminal tumor. PATIENT CONCERNS: A 69-year-old man with chronic obstructive pulmonary disease (COPD) presented with worsening dyspnea. A pulmonary function test showed severe airway obstruction and that forced expiratory volume in 1 s was 43% of the predicted value after a bronchodilator. DIAGNOSES: A bronchoscopy and histopathological analyses revealed a squamous cell carcinoma mostly located outside of the lumen with central airway obstruction...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28614095/the-value-of-dynamic-preload-variables-during-spontaneous-ventilation
#10
Azriel Perel
PURPOSE OF REVIEW: To discuss the physiological significance and clinical value of dynamic preload variables in spontaneously breathing patients. RECENT FINDINGS: Dynamic preload variables reflect the response of the cardiac output to a modification of preload and can therefore be used to assess fluid responsiveness. Continuous dynamic parameters that are calculated from the variations in the arterial and plethysmographic waveforms following a mechanical breath have been shown to predict fluid responsiveness much better than static preload parameters...
June 12, 2017: Current Opinion in Critical Care
https://www.readbyqxmd.com/read/28608295/influence-of-head-position-on-obstructive-sleep-apnea-severity
#11
Kaiyin Zhu, T Douglas Bradley, Maryam Patel, Hisham Alshaer
OBJECTIVE: Supine body orientation plays an important role in precipitating upper airway collapse in a significant proportion of obstructive sleep apnea (OSA) patients known to have supine-predominant OSA (OSAsup). Traditionally, trunk position is used to assess OSAsup, but the role of the head position has not been established. We hypothesized that head position influences OSA independently of trunk position. METHODS: Head and trunk positions were determined from subjects undergoing overnight polysomnography...
June 12, 2017: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/28599066/rhinovirus-and-pre-school-wheeze
#12
REVIEW
Katarina Stenberg-Hammar, Gunilla Hedlin, Cilla Söderhäll
Rhinovirus (RV) known as the common cold virus generally only causes a mild upper respiratory infection, but severe lower respiratory symptoms have been associated with RV infections especially in asthmatic individuals. Wheezing is a symptom of airway obstruction, and preschool children wheezing with RV have been associated with increased risk of asthma at school age. There are however conflicting opinions as to whether there are differences in response to RV infection or if wheezing with RV reveals a preexisting impairment that promotes asthma mainly in predisposed children...
June 9, 2017: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/28598766/tonsil-surgery-in-sweden-2013-2015-indications-surgical-methods-and-patient-reported-outcomes-from-the-national-tonsil-surgery-register
#13
Niclas Hallenstål, Ola Sunnergren, Elisabeth Ericsson, Claes Hemlin, Anne-Charlotte Hessén Söderman, Pia Nerfeldt, Erik Odhagen, Marie Ryding, Joacim Stalfors
AIM: To describes how tonsil surgery was performed in Sweden from 2013 to 2015 with data from the National Tonsil Surgery Registry in Sweden (NTSRS). METHOD: The registry collects data from both professionals and patients through questionnaires. A total of 33,870 tonsil surgeries were analysed, comprising approximately 80% of all tonsil surgeries in Sweden from 2013 to 2015. RESULTS: The two most common procedures were tonsillectomy (41%) and tonsillotomy with adenoidectomy (38%)...
June 9, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28591236/predictors-of-success-for-mandibular-repositioning-appliance-in-obstructive-sleep-apnea-syndrome
#14
Thays Crosara Abrahão Cunha, Thais de Moura Guimarães, Teresa Cristina Barros Schultz, Fernanda Ribeiro de Almeida, Thulio Marquez Cunha, Paulo Cezar Simamoto, Lia Rita Azeredo Bittencourt
The characteristics of non-obese patients with mild to moderate Obstructive Sleep Apnea Syndrome (OSAS) who will present with a good response to Mandibular Repositioning Appliance (MRA) treatment have not yet been well established in the literature. The aim of this study is to assess whether polysomnographic (PSG), demographic, anthropometric, cephalometric, and otorhinolaryngological parameters predict MRA success in the treatment of OSAS. Forty (40) males with mild and moderate OSAS were assessed pretreatment and 2-months post-treatment after wearing an MRA...
June 5, 2017: Brazilian Oral Research
https://www.readbyqxmd.com/read/28587125/equine-welfare-during-exercise-an-evaluation-of-breathing-breathlessness-and-bridles
#15
REVIEW
David J Mellor, Ngaio J Beausoleil
Horses engaged in strenuous exercise display physiological responses that approach the upper functional limits of key organ systems, in particular their cardiorespiratory systems. Maximum athletic performance is therefore vulnerable to factors that diminish these functional capacities, and such impairment might also lead to horses experiencing unpleasant respiratory sensations, i.e., breathlessness. The aim of this review is to use existing literature on equine cardiorespiratory physiology and athletic performance to evaluate the potential for various types of breathlessness to occur in exercising horses...
May 26, 2017: Animals: An Open Access Journal From MDPI
https://www.readbyqxmd.com/read/28584940/drug-induced-sedation-endoscopy-dise-classification-systems-a-systematic-review-and-meta-analysis
#16
REVIEW
Esuabom Dijemeni, Gabriele D'Amone, Israel Gbati
PURPOSE: Drug-induced sedation endoscopy (DISE) classification systems have been used to assess anatomical findings on upper airway obstruction, and decide and plan surgical treatments and act as a predictor for surgical treatment outcome for obstructive sleep apnoea management. The first objective is to identify if there is a universally accepted DISE grading and classification system for analysing DISE findings. The second objective is to identify if there is one DISE grading and classification treatment planning framework for deciding appropriate surgical treatment for obstructive sleep apnoea (OSA)...
June 6, 2017: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/28584606/giant-parapharyngeal-space-pleomorphic-adenoma-causing-acute-airway-obstruction
#17
Sampan S Bist, Mahima Luthra, Vinish Agrawal, Nadia Shirazi
Primary parapharyngeal space (PPS) tumors are rare, representing only 0.5% of all head and neck neoplasms. About 80% of tumors of this space are benign, and 20% are malignant. They often pose therapeutic and diagnostic problems due to variable non-specific symptoms and the complex anatomy of this space. Pleomorphic adenoma is the most common benign tumor of this space. It presents as an asymptomatic mass causing mild bulging in the soft palate or tonsillar region, or fullness near the angle of the mandible in the neck...
May 2017: Oman Medical Journal
https://www.readbyqxmd.com/read/28582298/flail-mandible-and-immediate-airway-management-traumatic-detachment-of-mandibular-lingual-cortex-results-in-obstructive-dyspnea-and-severe-odynophagia
#18
Ioannis Papadiochos, Lampros Goutzanis, Vasileios Petsinis
Isolated mandibular fractures usually represent themselves as non-life-threatening injuries and are not treated in emergency setting. However, some rare patterns of them may result in airway obstruction as a result of displacement of bony fragments. The authors report a patient of an open comminuted fracture of mandibular symphysis which exhibited an uncommon split pattern with retrogression of lingual cortical plate, and thereby induced glossoptosis, painful deglutition, and obstruction of the upper airway within a few hours...
June 2, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28580357/impact-of-compression-stockings-vs-continuous-positive-airway-pressure-on-overnight-fluid-shift-and-obstructive-sleep-apnea-among-patients-on-hemodialysis
#19
Bruno C Silva, Roberto S S Santos, Luciano F Drager, Fernando M Coelho, Rosilene M Elias
INTRODUCTION: Obstructive sleep apnea (OSA) is common in edematous states, notably in hemodialysis patients. In this population, overnight fluid shift can play an important role on the pathogenesis of OSA. The effect of compression stockings (CS) and continuous positive airway pressure (CPAP) on fluid shift is barely known. We compared the effects of CS and CPAP on fluid dynamics in a sample of patients with OSA in hemodialysis, through a randomized crossover study. METHODS: Each participant performed polysomnography (PSG) at baseline, during CPAP titration, and after 1 week of wearing CS...
2017: Frontiers in Medicine
https://www.readbyqxmd.com/read/28577340/abnormal-growth-and-feeding-behavior-persist-after-removal-of-upper-airway-obstruction-in-juvenile-rats
#20
Mohammad H Assadi, Elena Shknevsky, Yael Segev, Ariel Tarasiuk
Pediatric obstructive sleep-disordered breathing is associated with growth retardation, but also with obesity that has a tendency to persist following treatment. We investigated the effect of upper airways obstruction (AO) and of obstruction removal (OR) in juvenile rats on gut-derived ghrelin and related hypothalamic factors, feeding, and growth hormone (GH) homeostasis. Here, we show that after seven weeks of AO, animals gained less weight compared to controls, despite an increase in food intake due to elevated ghrelin and hypothalamic feeding factors...
June 2, 2017: Scientific Reports
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