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https://www.readbyqxmd.com/read/29453639/upper-airway-obstruction-induced-by-non-invasive-ventilation-using-an-oronasal-interface
#1
Valentin Schellhas, Christian Glatz, Ingo Beecken, Angelika Okegwo, Anna Heidbreder, Peter Young, Matthias Boentert
BACKGROUND: On initiation of long-term non-invasive ventilation (NIV), intermittent upper airway obstruction has rarely been described as possibly treatment-induced. Inspiratory pressure effects and the use of an oronasal interface may promote obstructive events in some patients with neuromuscular disease (NMD) and amyotrophic lateral sclerosis (ALS) in particular. METHODS: We evaluated clinical data from 212 patients in whom NIV was initiated using an oronasal mask...
February 17, 2018: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/29449609/kinesthetic-stimulation-for-obstructive-sleep-apnea-syndrome-an-on-off-proof-of-concept-trial
#2
Alfredo I Hernández, Diego Pérez, Delphine Feuerstein, Corinne Loiodice, Laurence Graindorge, Gustavo Guerrero, Nadège Limousin, Frédéric Gagnadoux, Yves Dauvilliers, Renaud Tamisier, Arnaud Prigent, Philippe Mabo, Amel Amblard, Lotfi Senhadji, Jean-Louis Pépin
Obstructive sleep apnea (OSA) occurs when the upper airway narrows or collapses due to the loss of upper airway muscle activation at sleep onset. This study investigated the effectiveness of triggered kinesthetic stimulation in patients with OSA. This proof-of-concept, open-label, multicenter prospective study was conducted on 24 patients with severe OSA. During a one night evaluation, kinesthetic stimulation was intermittently delivered in 30 minute periods. The duration of apneas and hypopneas during Stim on and Stim off periods were compared...
February 15, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29447802/effects-of-maxillary-protraction-appliances-on-airway-dimensions-in-growing-class-iii-maxillary-retrognathic-patients-a-systematic-review-and-meta-analysis
#3
REVIEW
Ye Ming, Yun Hu, Yuyue Li, Jinfeng Yu, Haojue He, Leilei Zheng
OBJECTIVES: The purpose of this study was to assess, through a systematic review and meta-analysis, the efficacy of maxillary protraction appliances (MPAs) on improving pharyngeal airway dimensions in growing class III patients with maxillary retrognathism. METHODS: An electronic search in PubMed, Cochrane Library, Web of Science, and EMBASE was until September 2nd, 2017. The assessments of methodological quality of the selected articles were performed using the Newcastle-Ottawa Scale...
February 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29446988/diagnosing-tongue-base-obstruction-in-pierre-robin-sequence-infants-sleep-vs-awake-endoscopy
#4
Jake J Lee, Matthew D Ford, Allison B Tobey, Noel Jabbour
OBJECTIVE: To investigate whether awake endoscopy can diagnose base-of-tongue obstruction as reliably as sleep endoscopy in infants with Pierre Robin sequence (PRS). DESIGN: The study was retrospective with the clinicians blinded to patient identity. Endoscopy findings were assessed and measured by the performing pediatric otolaryngologist. SETTING: Tertiary care children's hospital. PATIENTS: All infants with PRS managed between January 2005 and July 2015 were included...
January 1, 2018: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/29445529/cardiorespiratory-interaction-with-continuous-positive-airway-pressure
#5
REVIEW
Martino F Pengo, Sara Bonafini, Cristiano Fava, Joerg Steier
The treatment of choice for obstructive sleep apnoea (OSA) is continuous positive airway pressure therapy (CPAP). Since its introduction in clinical practice, CPAP has been used in various clinical conditions with variable and heterogeneous outcomes. In addition to the well-known effects on the upper airway CPAP impacts on intrathoracic pressures, haemodynamics and blood pressure (BP) control. However, short- and long-term effects of CPAP therapy depend on multiple variables which include symptoms, underlying condition, pressure used, treatment acceptance, compliance and usage...
January 2018: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29445527/drug-induced-sleep-endoscopy-its-role-in-evaluation-of-the-upper-airway-obstruction-and-patient-selection-for-surgical-and-non-surgical-treatment
#6
REVIEW
Bhik Kotecha, Andrea De Vito
Sleep related breathing disorders cause obstruction of the upper airway which can be alleviated by continuous positive airway pressure (CPAP) therapy, oral devices or surgical intervention. Non-surgical treatment modalities are not always accepted by patients and in order to attain successful surgical outcomes, evaluation of the upper airway is necessary to carefully select the patients who would benefit from surgery. There are numerous techniques available to assess the upper airway obstruction and these include imaging, acoustic analysis, pressure transducer recording and endoscopic evaluation...
January 2018: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29440942/mandibular-positioning-techniques-to-improve-sleep-quality-in-patients-with-obstructive-sleep-apnea-current-perspectives
#7
REVIEW
Sofie Wilkens Knappe, Liselotte Sonnesen
The purpose of this article is to review 1) mandibular advancement device (MAD) - indication, treatment success, and side effects; 2) maxillomandibular advancement (MMA) surgery of the jaws - indication, treatment success, and side effects; and 3) current perspectives. Both MAD and MMA are administered to increase the upper airway volume and reduce the collapsibility of the upper airway. MAD is noninvasive and is indicated as a first-stage treatment in adult patients with mild-to-moderate obstructive sleep apnea (OSA) and in patients with severe OSA unable to adhere to continuous positive airway pressure (CPAP)...
2018: Nature and Science of Sleep
https://www.readbyqxmd.com/read/29433716/percutaneous-dilational-tracheostomy
#8
REVIEW
Andrew D Lerner, Lonny Yarmus
Tracheostomy tubes can be inserted surgically or percutaneously via percutaneous dilational tracheostomy (PDT). Tracheostomy is performed for upper airway obstruction, though more often to allow prolonged mechanical ventilation in place of endotracheal tubes. Preparation, performance, and postoperative management for PDT are best provided by a multidisciplinary team. Although PDT is a safe procedure in the hands of experienced operators, both early and late complications can arise. Caution must also be taken during early tracheostomy tube exchange given that immaturity of the stomal tract can risk loss of the airway...
March 2018: Clinics in Chest Medicine
https://www.readbyqxmd.com/read/29416383/obstructive-sleep-apnea-current-perspectives
#9
REVIEW
Amal M Osman, Sophie G Carter, Jayne C Carberry, Danny J Eckert
The prevalence of obstructive sleep apnea (OSA) continues to rise. So too do the health, safety, and economic consequences. On an individual level, the causes and consequences of OSA can vary substantially between patients. In recent years, four key contributors to OSA pathogenesis or "phenotypes" have been characterized. These include a narrow, crowded, or collapsible upper airway "anatomical compromise" and "non-anatomical" contributors such as ineffective pharyngeal dilator muscle function during sleep, a low threshold for arousal to airway narrowing during sleep, and unstable control of breathing (high loop gain)...
2018: Nature and Science of Sleep
https://www.readbyqxmd.com/read/29414449/mucus-hypersecretion-in-asthma-is-associated-with-rhinosinusitis-polyps-and-exacerbations
#10
Carlos Martínez-Rivera, Astrid Crespo, Celia Pinedo-Sierra, Juan L García-Rivero, Abel Pallarés-Sanmartín, Núria Marina-Malanda, Silvia Pascual-Erquicia, Alicia Padilla, Sagrario Mayoralas-Alises, Vicente Plaza, Antolín López-Viña, César Picado
BACKGROUND: Bronchial hypersecretion is a poorly studied symptom in asthma. The aim of the study was to determine the specific characteristics of asthmatics with bronchial hypersecretion. METHODS: A total of 142 asthmatics (21.8% men; mean age 49.8 years) were prospectively followed for one year. Mucus hypersecretion was clinically classified into two severity categories: daily sputum production and frequent expectoration but not every day. Clinical and pulmonary function variables associated with mucus hypersecretion were assessed by multiple logistic regression analysis...
February 2018: Respiratory Medicine
https://www.readbyqxmd.com/read/29410749/surgical-treatment-of-a-pattern-i-obstructive-sleep-apnea-syndrome-individual-clinical-case-report
#11
Christiane Cavalcante Feitoza, Matheus Corrêa da-Silva, Yasmim Lima Nascimento, Elaine Sobral Leite, Corintho Viana Pereira, Lucas Gomes Patrocínio
Obstructive Sleep Apnea Syndrome (OSA) is a multifactorial disease that highly alters a persons quality of life. It is characterized by the repeated interruption of breathing during sleep, due to an obstruction or the collapse of the upper airways. Since it is a multifactorial etiological disorder, it requires a thorough diagnosis and treatment with an interdisciplinary team, which comprises several professionals such as a surgical dentist, phonoaudiologist, otorhinolaryngologist, sleep doctor, neurologist and physiotherapist...
October 2017: Sleep Science
https://www.readbyqxmd.com/read/29410742/lip-muscle-training-improves-obstructive-sleep-apnea-and-objective-sleep-a-case-report
#12
Hiroshi Suzuki, Mayuko Yoshimiura, Yoshihiro Iwata, Sumito Oguchi, Misao Kawara, Chin-Moi Chow
The present study assessed the potential of lip muscle training for improving sleep. A patient with heavy snoring, daytime sleepiness and dry mouth underwent lip muscle training. Lip closure force LCFmax increased by 67.3% and LCFmin by 152% post-training. AHI decreased from 12.2 to 3.9 events/h by reducing hypopneic episodes. TST, sleep stage N3 and REM sleep increased, and WASO, sleep stage N1, and AI decreased. The patient switched from mouth to nose breathing during sleep and stopped snoring. Improved LCF, by moving the tongue into the anterior-superior oral cavity, may increase upper airway space and reduce the hypopnea index...
July 2017: Sleep Science
https://www.readbyqxmd.com/read/29410358/hypoglossal-nerve-stimulation-in-a-pre-clinical-anesthetized-rabbit-model-relevant-to-osa
#13
Girriso F Benderro, Jenniffer Gamble, Matthew A Schiefer, Jonathan Z Baskin, Yeritza Hernandez, Kingman P Strohl
We tested the functional effects of hypoglossal (CNXII) stimulation in the anesthetized rabbit before and after injections of saline into the tongue base to obstruct the airway. Data (n = 6) show little or no effect of CN XII trunk stimulation; however, medial branch stimulation (20-100 Hz; 50-500 μs pulse width, and incremental increases from 10 μA) reduced upper airway resistance. Medial branch stimulation was less effective in reducing resistance than anterior advancement of the hyoid. Endoscopic viewing (n-3) of the retropalate showed this region as the narrowest and dynamically changed by anterior hyoid displacement, with less evident effects than CNXII stimulation...
February 1, 2018: Respiratory Physiology & Neurobiology
https://www.readbyqxmd.com/read/29398406/indoor-air-humidity-air-quality-and-health-an-overview
#14
REVIEW
Peder Wolkoff
There is a long-standing dispute about indoor air humidity and perceived indoor air quality (IAQ) and associated health effects. Complaints about sensory irritation in eyes and upper airways are generally among top-two symptoms together with the perception "dry air" in office environments. This calls for an integrated analysis of indoor air humidity and eye and airway health effects. This overview has reviewed the literature about the effects of extended exposure to low humidity on perceived IAQ, sensory irritation symptoms in eyes and airways, work performance, sleep quality, virus survival, and voice disruption...
January 31, 2018: International Journal of Hygiene and Environmental Health
https://www.readbyqxmd.com/read/29397301/-vocal-cord-dyskinesia-and-or-asthma
#15
J J Braun, C Delmas, A Charloux, P Schultz, F de Blay
INTRODUCTION: Vocal cord dyskinesia or vocal cord dysfunction (VCD) is characterized by intermittent abnormal adduction of the vocal cords leading to airflow limitation at the level of the larynx, in the absence of local organic disease. It may occur in isolation or in association with asthma. The pathophysiology is complex and poorly understood. Wheeze, stridor or apparent upper airway obstruction are the most common symptoms. It occurs in a wide age range, more commonly in women, and diagnosis is often delayed and leads to unnecessary treatments (intubation, tracheostomy and high dose steroids)...
January 31, 2018: Revue des Maladies Respiratoires
https://www.readbyqxmd.com/read/29392975/respiratory-digestive-tract-fistula-two-center-retrospective-observational-study
#16
Sameh I Sersar, Lamees A Maghrabi
Background Aerodigestive fistulae can be defined as abnormal communications between the gastrointestinal tract and the respiratory tract. Choking after meals, coughing, feeding difficulties, tachycardia, and persistent pneumonia are the main presentations. The aim of our study was to review our experience in the management of 27 cases of acquired aerodigestive fistulae of different types, levels, and management. Methods We conducted a retrospective observational study on 27 cases of fistulae between the respiratory and digestive tracts, which were managed in 2 hospitals in Saudi Arabia in the last 5 years...
January 1, 2018: Asian Cardiovascular & Thoracic Annals
https://www.readbyqxmd.com/read/29392051/dyspnea-associated-with-henna-stone-a-rare-cause-of-pediatric-tracheotomy
#17
Selis Gülseven Güven
Tracheotomy is one of the oldest surgical procedures, and it is a life-saving procedure to overcome upper airway obstructions. While congenital causes play an important role in pediatric tracheotomy indications, upper airway edema and obstruction due to anaphylaxis rarely require tracheotomy. Allergy can cause life-threatening acute edema by anaphylactic reactions in the respiratory tract. Henna stone is the material for dyeing hair with henna and making a temporary tattoo. It contains high proportions of paraphenylendiamine...
March 2017: Turkish archives of otorhinolaryngology
https://www.readbyqxmd.com/read/29391572/obstructive-sleep-apnoea
#18
REVIEW
Sophie D West, Chris Turnbull
Obstructive sleep apnoea (OSA) is increasing in prevalence due to rising obesity. While OSA is a disorder primarily of the upper airway during sleep, its pathophysiological impact on other body systems is increasingly recognised. There has been interest in the prevalence of OSA in different ophthalmic conditions and possible causation has been postulated. As OSA is common, it can be expected that people with co-existent OSA will be found in any ophthalmic disease population studied. To determine with confidence the significance of finding patients with OSA in a particular cohort requires a well matched control group, ideally matched for age, obesity, gender and co-morbidities...
February 2, 2018: Eye
https://www.readbyqxmd.com/read/29390419/influencing-factors-on-cpap-adherence-and-anatomic-characteristics-of-upper-airway-in-osa-subjects
#19
Pona Park, Jinil Kim, Yoon Jae Song, Jae Hyun Lim, Sung Woo Cho, Tae-Bin Won, Doo Hee Han, Dong-Young Kim, Chae Seo Rhee, Hyun Jik Kim
Although continuous positive airway pressure (CPAP) is the most effective treatment modality, poor adherence still remains a problem for obstructive sleep apnea (OSA) treatment and there is little evidence regarding how this might be improved. This study aims to analyze the anatomic and clinical factors of OSA subjects who failed to comply with CPAP therapy.The medical records of 47 OSA subjects who received CPAP therapy as a first-line treatment modality were retrospectively reviewed. The medical records were reviewed for demographic and polysomnographic data and anatomic findings of the nasal cavity and oropharynx...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29381611/decannulation-and-airway-outcomes-with-maxillomandibular-distraction-in-treacher-collins-and-nager-syndrome
#20
Nataliya I Biskup, Brian S Pan, Haithem Elhadi-Babiker, Ronald R Hathaway, John van Aalst, Christopher B Gordon
BACKGROUND: Treacher Collins syndrome is a rare disorder (1/50,000 live births) with features that include hypoplastic orbitozygomatic complex with downward slanting eyes, and maxillary/mandibular retrusion. Obstructive sleep apnea and tracheostomy-dependence are common. This study presents the outcomes of skeletal distraction on avoidance of tracheostomy and decannulation in this patient population. METHODS: The authors reviewed charts of all patients with Treacher Collins syndrome who underwent craniofacial reconstruction from 2003 to 2016...
January 29, 2018: Journal of Craniofacial Surgery
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