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https://www.readbyqxmd.com/read/29349878/efficacy-of-grape-seed-extract-gel-in-the-treatment-of-chronic-periodontitis-a-randomized-clinical-study
#1
Mohammad Rayyan, Tammam Terkawi, Hajer Abdo, Dalia Abdel Azim, Aseel Khalaf, Zenab AlKhouli, Maha Meziad, Marwa Alshamma'a, Horiyah Abu Naim
AIM: The aim of the present study was to assess the effectiveness of applying grape seed extract (GSE) gel in periodontal pockets for the treatment of chronic periodontitis. METHODS: Eighty-six sites with pocket depth (PD) >4 mm were selected from five systemically-healthy patients in whom scaling, and root planing were performed, and oral instructions were given, a week earlier. PD, gingival index (GI), plaque index (PI), and bleeding on probing (BOP) were measured, and sites were then divided into the control group (N = 38) and GSE group (N = 48)...
January 18, 2018: Journal of Investigative and Clinical Dentistry
https://www.readbyqxmd.com/read/29348397/placement-of-an-aortohepatic-conduit-as-an-alternative-to-standard-arterial-anastomosis-in-liver-transplantation
#2
Dong-Hwan Jung, Cheon-Soo Park, Tae-Yong Ha, Gi-Won Song, Gil-Chun Park, Yong-Pil Cho, Sung-Gyu Lee
BACKGROUND The aim of this study was to assess the impact of placement of an aortohepatic conduit on graft and patient survival after liver transplantation (LT) in selected patients with an inadequate recipient hepatic artery (HA) for a standard arterial anastomosis. MATERIAL AND METHODS Of 331 patients who underwent deceased donor LT, 25 (7.6%) who received placement of an aortohepatic conduit at the time of transplantation were included. Clinical characteristics and outcomes, including postoperative complications, conduit patency, and graft and patient survival rates, were analyzed...
January 19, 2018: Annals of Transplantation: Quarterly of the Polish Transplantation Society
https://www.readbyqxmd.com/read/29346827/efficacy-and-complications-of-submucosal-tunneling-endoscopic-resection-for-upper-gastrointestinal-submucosal-tumors-and-exploration-for-influencing-factors
#3
Shunzhe Song, Xu Wang, Shen Zhang, Yanxia Li, Xiaonan Zhang, Xufang Chu
BACKGROUND:  Submucosal tunneling endoscopic resection (STER) has emerged as a feasible technique for resecting upper gastrointestinal (GI) tract submucosal tumors (SMTs) through natural orifice transluminal endoscopic surgery. STER reduces the risk of postoperative perforation and abdominal infections and promotes rapid wound healing. The aim of this meta-analysis was to evaluate the safety and efficacy of STER for small (≤ 3.5 cm) upper GI SMTs and explore the potential factors influencing STER's efficacy and complication rate...
January 18, 2018: Zeitschrift Für Gastroenterologie
https://www.readbyqxmd.com/read/29346334/effect-of-gastrointestinal-bleeding-on-gastrointestinal-stromal-tumor-patients-a-retrospective-cohort-study
#4
Yuqian Huang, Rui Zhao, Yaping Cui, Yong Wang, Lin Xia, Yi Chen, Yong Zhou, Xiaoting Wu
BACKGROUND The contemporary risk classification criteria of gastrointestinal stromal tumors (GISTs) may still have room to improve. The aim of our research was to analyze the impact factors for GIST patients' relapse-free survival (RFS). Furthermore, we explore whether gastrointestinal (1) bleeding will be a valuable indicator to predict GIST patients' prognosis. MATERIAL AND METHODS R0 resection GISTs patients were retrospectively enrolled during an 8-year period at West China Hospital of Sichuan University, and all patients' data were from the WCHSU-GIST database...
January 18, 2018: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29343478/treatment-of-gastrointestinal-bleeding-with-idarucizumab-in-a-patient-receiving-dabigatran
#5
Jennifer Mourafetis, Norman Doctor, Simon Leung
PURPOSE: A case report describing use of idarucizumab for dabigatran reversal without the use of hemostatic agents in a patient who developed acute upper gastrointestinal (GI) bleeding while receiving triple antithrombotic therapy is presented. SUMMARY: A 77-year-old man with a complex cardiac history presented to the emergency room with chief complaints of black tarry stools and low blood pressures for 4 days. His past medical history included recent percutaneous coronary intervention (PCI) and drug-eluting stent (DES) placement, atrial fibrillation, hypertension, hyperlipidemia, coronary artery disease, coronary artery bypass graft surgery, stage 3 chronic kidney disease, and cholecystectomy...
January 17, 2018: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/29325750/double-balloon-enteroscopy-dbe-in-patients-presenting-with-obscure-gastrointestinal-bleeding-ogib
#6
Esmat Sheba, Ali Farag, Wael Aref, Shaimaa Elkholy, Omar Ashoush
BACKGROUND AND STUDY AIMS: Obscure gastrointestinal bleeding (OGIB) is defined as bleeding of unknown origin that persists or recurs after an initial negative investigation. Identifying the source of OGIB represents a diagnostic challenge that is frequently focused on visualizing the small intestine. Conventional diagnostic methods, such as push enteroscopy, small-bowel follow-through, radionuclide scanning, and angiography, each exhibit inherent limitations. Double balloon enteroscopy (DBE) was designed specifically to evaluate the entire small bowel...
January 8, 2018: Arab Journal of Gastroenterology: the Official Publication of the Pan-Arab Association of Gastroenterology
https://www.readbyqxmd.com/read/29314744/clinical-and-economic-implications-of-upper-gastrointestinal-adverse-events-in-asian-rheumatological-patients-on-long-term-non-steroidal-anti-inflammatory-drugs
#7
Lydia Say Lee Pok, Fatiha Hana Shabaruddin, Maznah Dahlui, Sargunan Sockalingam, Mohd Shahrir Mohamed Said, Azmillah Rosman, Ing Soo Lau, Liza Mohd Isa, Heselynn Hussein, Chin Teck Ng, Sanjiv Mahadeva
AIM: To determine the incidence and direct costs of NSAID-induced upper GI adverse events in Malaysian rheumatology patients. METHODS: A retrospective, multi-centre, cohort study of rheumatology patients on long-term NSAIDs was conducted. Clinical data of patients treated between 2010 and 2013 were collected for a 24-month follow-up period. The costs of managing upper GI adverse events were based on patient level resource use data. RESULTS: Six hundred and thirty-four patients met the inclusion criteria: mean age 53...
January 5, 2018: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/29314627/etiology-of-gastrointestinal-bleeding-in-patients-on-dual-antiplatelet-therapy
#8
Arslan Shaukat, Salman Waheed, Ethan Alexander, Daniel Washko, Buddhadeb Dawn, Mojtaba Olyaee, Kamal Gupta
BACKGROUND: Dual antiplatelet therapy (DAPT) is associated with an increased risk of gastrointestinal bleeding (GIB). Traditionally thought to cause mostly upper GIB (UGIB), some recent reports suggest that incidence of lower GIB (LGIB) may be increasing. We conducted a study to assess the endoscopic findings and etiology of GIB in patients who presented with GIB on DAPT compared to those not on DAPT. METHODS: This is a retrospective, single center, case control study...
January 4, 2018: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/29308001/chronic-kidney-disease-severely-deteriorates-the-outcome-of-gastrointestinal-bleeding-a-meta-analysis
#9
Roland Hágendorn, Nelli Farkas, Áron Vincze, Zoltán Gyöngyi, Dezső Csupor, Judit Bajor, Bálint Erőss, Péter Csécsei, Andrea Vasas, Zsolt Szakács, László Szapáry, Péter Hegyi, Alexandra Mikó
AIM: To understand the influence of chronic kidney disease (CKD) on mortality, need for transfusion and rebleeding in gastrointestinal (GI) bleeding patients. METHODS: A systematic search was conducted in three databases for studies on GI bleeding patients with CKD or end-stage renal disease (ESRD) with data on outcomes of mortality, transfusion requirement, rebleeding rate and length of hospitalization (LOH). Calculations were performed with Comprehensive Meta-Analysis software using the random effects model...
December 21, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29305021/risk-factors-associated-with-clinically-significant-gastrointestinal-bleeding-in-pediatric-emergency-department
#10
Ayse Gultekingil, Ozlem Teksam, Hayriye Hızarcıoğlu Gulsen, Burcu Berberoğlu Ates, İnci Nur Saltık-Temizel, Hülya Demir
INTRODUCTION: Gastrointestinal bleeding is a common problem in pediatric emergency department (PED). Some of these patients can lose significant amount of blood which may lead to shock. The aim of this study is to determine the risk factors predicting clinically significant gastrointestinal (GIS) bleeding in patients presenting to PED. METHODS: This study was performed prospectively from January 1st 2013 to December 31th 2013 in patients with upper or lower GIS bleeding...
December 12, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29290788/investigating-esophageal-stent-placement-outcomes-in-patients-with-inoperable-non-cervical-esophageal-cancer
#11
Mojgan Forootan, Morteza Tabatabaeefar, Nariman Mosaffa, Hormat Rahimzadeh Ashkalak, Mohammad Darvishi
Background: Esophageal stent insertion in patients with inoperable esophageal cancer is usually accompanied with relatively high adverse symptoms and even mortality. The current study aims at investigating the outcomes of esophageal stenting in patients with inoperable non-cervical esophageal cancer. Materials and Methods: The current descriptive-analytical research evaluates 25 patients with esophageal cancer. The stent was placed in esophagus based upon endoscopy analysis with or without fluoroscopy and then the stent position and its opening was investigated by making use of CXRand Gastrografin studies...
2018: Journal of Cancer
https://www.readbyqxmd.com/read/29287004/non-invasive-markers-of-portal-hypertension-appraisal-of-adult-experience-and-potential-utilisation-in-children
#12
Harry Sutton, Anil Dhawan, Tassos Grammatikopoulos
Portal Hypertension (PHT) is a significant cause of morbidity and mortality in children with chronic liver disease (CLD) and portal vein obstruction. Increased portal pressure results in variceal formation along the gastrointestinal (GI) tract resulting in major bleeding. Identifying children with significant PHT who are more likely to suffer GI bleeding has been challenging and the role of surveillance upper GI endoscopy has been debated. This review analyses research done on serum biomarkers and imaging techniques as possible predictors of significant PHT...
December 28, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29282382/massive-upper-and-lower-gi-bleed-from-simultaneous-primary-al-amyloidosis-of-the-stomach-and-transverse-colon-in-a-patient-with-multiple-myeloma
#13
Zubair Khan, Umar Darr, Anas Renno, Abhinav Tiwari, Aijaz Sofi, Ali Nawras
Symptomatic primary (amyloid light-chain or AL) amyloidosis of the gastrointestinal (GI) tract is very rare. Most of the patients with symptomatic involvement of the GI tract present with altered motility, malabsorption, or bleeding. We report a case of gastric and colonic amyloidosis on anticoagulation presenting with massive upper and lower GI bleeding. A 67-year-old lady known to have multiple myeloma and AL amyloidosis on rivaroxaban presented with massive upper GI bleeding. Esophagogastroduodenoscopy showed a mass lesion (3 × 7 cm) located along the greater curvature in the body/antrum with active bleeding...
September 2017: Case Reports in Gastroenterology
https://www.readbyqxmd.com/read/29260002/profile-of-extrahepatic-portal-venous-obstruction-among-children-in-central-india
#14
Mayank Jain, Jenisha Jain, Gauri Rao Passi, Kamna Jain, Shikhar Jain
Introduction: There is a paucity of data regarding the clinical profile of children with extrahepatic portal venous obstruction (EHPVO) from Central India. Material and methods: Retrospective analysis of 30 children with EHPVO treated between 2002 and 2012. Results: The median age of presentation was 12.5 years (range 5-14 years) and median duration of symptoms was 3.2 years (range 0.3-10 years). Home delivery was noted in 30 cases (100%), umbilical sepsis in 8 (27%) and history of cow dung application over the umbilical cord in 2 cases (6...
December 2017: Clinical and Experimental Hepatology
https://www.readbyqxmd.com/read/29247519/real-world-incidence-of-efficacy-and-safety-outcomes-in-patients-on-direct-oral-anticoagulants-with-left-ventricular-systolic-dysfunction-at-a-tertiary-referral-center
#15
Andrew S Tseng, J William Schleifer, Win-Kuang Shen, Robert McBane, Sunil Mankad, Heidi Esser, Darko Vucicevic, Fadi E Shamoun
BACKGROUND: Patients with heart failure (HF) have increased risk for thromboembolic events. Real-world incidences of efficacy and safety outcomes of direct oral anticoagulants (DOACs) in patients with left ventricular systolic dysfunction (LVSD) are of growing clinical interest. HYPOTHESIS: Real-world efficacy and safety outcomes of DOACs in patients with LVSD will be similar to those of LVSD or HF subgroups in the RE-LY, ROCKET-AF, and ARISTOTLE trials. METHODS: We performed a retrospective review of adult patients with LVSD (left ventricular ejection fraction ≤40%) on DOAC therapy between 2010 and 2016...
December 16, 2017: Clinical Cardiology
https://www.readbyqxmd.com/read/29245228/use-of-concomitant-variceal-embolization-and-prophylactic-antiplatelet-anticoagulative-in-transjugular-intrahepatic-portosystemic-shunting-a-retrospective-study-of-182-cirrhotic-portal-hypertension-patients
#16
Yingmei Tang, Sheng Zheng, Jinhui Yang, Weimin Bao, Lihong Yang, Yingchun Li, Ying Xu, Jing Yang, Yuyun Tong, Jinhang Gao, Chengwei Tang
Transjugular intrahepatic portosystemic shunting (TIPS) is an effective treatment modality for refractory variceal bleeding and ascites in patients with cirrhotic portal hypertension (CPH). Variceal rebleeding and shunt dysfunction are major post-TIPS morbidities. This study aimed to retrospectively evaluate the effectiveness and safety of use of concomitant variceal embolization and prophylactic antiplatelet/anticoagulative in patients with CPH undergoing TIPS. Between October 2006 and October 2011, 182 patients with CPH were retrospectively and consecutively hospitalized for elective TIPS with Fluency stenting...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29230562/risks-of-bleeding-and-thrombosis-in-intensive-care-unit-patients-with-haematological-malignancies
#17
Lene Russell, Lars Broksø Holst, Lars Kjeldsen, Jakob Stensballe, Anders Perner
BACKGROUND: Patients with malignant haematological disease and especially those who require intensive care have an increased risk of bleeding and thrombosis, but none of these data were obtained in ICU patients only. We assessed the incidence of bleeding and thrombotic complications, use of blood products and risk factors for bleeding in an adult population of ICU patients with haematological malignancies. METHODS: We screened all patients with acute leukaemia and myelodysplastic syndrome admitted to a university hospital ICU during 2008-2012...
December 11, 2017: Annals of Intensive Care
https://www.readbyqxmd.com/read/29224657/cta-as-an-adjuvant-tool-for-acute-intra-abdominal-or-gastrointestinal-bleeding
#18
REVIEW
Mitchell Storace, Jonathan G Martin, Jay Shah, Zachary Bercu
Hematemesis and acute postsurgical upper gastrointestinal hemorrhage are common emergent on-call consultations for the interventional radiologist. Upper GI bleleding (UGIB) is a relatively frequent problem. The incidence and mortality vary among patient populations, but studies have shown an overall incidence ranging from 36-172 cases per 100,000 adults per year, with a mortality rate of 5%-14%. The incidence is significantly higher in men. Peptic ulcer disease is the predominant etiology, responsible for 28%-59% of UGIB...
December 2017: Techniques in Vascular and Interventional Radiology
https://www.readbyqxmd.com/read/29215478/tranexamic-acid-for-lower-gi-hemorrhage-a-randomized-placebo-controlled-clinical-trial
#19
RANDOMIZED CONTROLLED TRIAL
Stephen R Smith, David Murray, Peter G Pockney, Cino Bendinelli, Brian D Draganic, Rosemary Carroll
BACKGROUND: Lower GI hemorrhage is a common source of morbidity and mortality. Tranexamic acid is an antifibrinolytic that has been shown to reduce blood loss in a variety of clinical conditions. Information regarding the use of tranexamic acid in treating lower GI hemorrhage is lacking. OBJECTIVE: The aim of this trial was to determine the clinical efficacy of tranexamic acid when used for lower GI hemorrhage. DESIGN: This was a prospective, double-blind, placebo-controlled, randomized clinical trial...
January 2018: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/29215411/a-novel-technique-to-measure-the-intensity-of-abnormality-on-gi-bleeding-scans-development-initial-implementation-and-correlation-with-conventional-angiography
#20
Rami Farhat, Derek T Kim, T Dustin French, Dov Bechhofer, Anca-Oana Kranz, Jason C Hoffmann
PURPOSE: Develop a technique to quantify intensity of lower gastrointestinal bleeding (LGIB) on Tc-labeled red blood cell (RBC) scintigraphy, correlate with angiography, and determine the tool's predictive value. MATERIALS AND METHODS: An IRB-approved, single institution database query of GI bleeding scans performed between January 2013 and December 2015. Reports from all studies and imaging from all positive studies were reviewed. A technique was developed for scan analysis, allowing for calculation of percent increase of activity in the region of interest (ROI, area of bleeding) and ROI in the aorta and liver (controls)...
December 5, 2017: Clinical Nuclear Medicine
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