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https://www.readbyqxmd.com/read/28533916/pediatric-intensive-care-stress-ulcer-prevention-pic-up-a-protocol-for-a-pilot-randomized-trial
#1
Mark Duffett, Karen Choong, Jennifer Foster, Elaine Gilfoyle, Jacques Lacroix, Nikhil Pai, Lehana Thabane, Deborah J Cook
BACKGROUND: Despite sparse pediatric data on effectiveness, the majority of critically ill children receive medications to prevent gastrointestinal (GI) bleeding. Stress ulcer prophylaxis may have unintended consequences-increasing the risk of nosocomial infections-which may be more serious and common than the bleeding which these drugs are prescribed to prevent. Randomized controlled trials (RCTs) in pediatric critical care are exceptionally challenging to complete, thus a rigorous pilot RCT is crucial...
2017: Pilot and Feasibility Studies
https://www.readbyqxmd.com/read/28524623/upper-gastrointestinal-complications-following-ablation-therapy-for-atrial-fibrillation
#2
S-Y Park, M Camilleri, D Packer, K Monahan
BACKGROUND: Following ablation therapy for cardiac arrhythmias, patients may develop upper gastrointestinal (UGI) symptoms. The vagus nerve is close to the atria and may be affected by ablating energy. AIM: To identify structural or functional complications in UGI tract following ablation for atrial fibrillation (AF) and clinical outcomes and association with vagal dysfunction. METHODS: Using natural language processing of electronic medical records and an AF ablation database of 5380 patients treated during 17 years, we identified 40 patients with UGI complications...
May 19, 2017: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/28523954/photometric-cielab-analysis-of-the-gingiva-a-novel-approach-to-assess-response-to-periodontal-therapy
#3
Yaniv Mayer, Ofir Ginesin, Eli E Machtei
OBJECTIVE: A new photometric method is introduced for the assessment of the gingival condition and changes following periodontal therapy. MATERIAL AND METHODS: Clinical data (probing depth, plaque index, gingival index, bleeding on probing, clinical attachment level) and photographs from 53 subjects (49% males, 51% females) undergoing initial periodontal treatment were used for this analysis. Each maxillary anterior area was photographed before treatment and three months after...
May 19, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28507366/over-a-decade-of-changing-trends-in-surgical-mortality-audit-from-a-tertiary-care-hospital
#4
Hassaan Bari, Khawaja Mohammad Inam Pal, Akbar Jaleel Zubairi
OBJECTIVE: A retrospective audit of the trend of mortality in the general surgery service at our hospital over the last decade was conducted to reflect the complexity of cases being seen. METHODS: Mortalities of 8 separate years, a decade apart, namely 1997, 1998, 1999, and 2000 as initial years (Group-I) and 2011, 2012, 2013 and 2014 as recent years (Group-II) were reviewed. RESULTS: Total number of admissions in the service and surgeries performed during these two periods experienced an increase of 50...
May 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28496533/the-diagnostic-value-of-alarm-features-for-identifying-types-and-stages-of-upper-gastrointestinal-malignancies
#5
Shou-Wu Lee, Chi-Sen Chang, Hong-Jeh Yeh, Han-Chung Lien, Teng-Yu Lee, Yen-Chun Peng
BACKGROUND: Upper gastrointestinal (GI) malignancies are an uncommon cause of dyspepsia but of great concern. The aim of this study was to determine the association between alarm features and each type and stage of upper GI malignancies. METHODS: Patients who underwent endoscopy for symptoms of dyspepsia between January 2008 and December 2009 were retrospectively collected. Alarm features studied in this study were dysplasia, body weight loss and GI bleeding. Patients were classified according to the findings of endoscopy and histological reports...
April 2017: Gastroenterology Research
https://www.readbyqxmd.com/read/28495536/neoaortoiliac-system-procedure-to-treat-infected-aortic-grafts
#6
Chris Klonaris, Nikolaos Patelis, Athanasios Katsargyris, Dimitrios Athanasiadis, Andreas Alexandrou, Theodoros Liakakos
OBJECTIVE: The aim of this case series is to report the results of our centre in the surgical treatment of infected abdominal aortic grafts using the neo-aortoiliac system (NAIS) procedure. PATIENTS AND METHODS: Four male and two female patients underwent a NAIS repair after endovascular (n=3), open (n=2) or combined surgery (n=1) in our centre. Mean age was 73±5.2 years. Graft infection was diagnosed by computed tomography angiography (CTA) and only in two cases further imaging was necessary...
May 8, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28487603/endoscopic-management-of-pancreatic-fluid-collections-revisited
#7
REVIEW
Zaheer Nabi, Jahangeer Basha, D Nageshwar Reddy
The development of pancreatic fluid collections (PFC) is one of the most common complications of acute severe pancreatitis. Most of the acute pancreatic fluid collections resolve and do not require endoscopic drainage. However, a substantial proportion of acute necrotic collections get walled off and may require drainage. Endoscopic drainage of PFC is now the preferred mode of drainage due to reduced morbidity and mortality as compared to surgical or percutaneous drainage. With the introduction of new metal stents, the efficiency of endoscopic drainage has improved and the task of direct endoscopic necrosectomy has become easier...
April 21, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28485544/tc-325-versus-the-combined-conventional-technique-for-endoscopic-treatment-of-peptic-ulcers-with-high-risk-bleeding-stigmata-a-pilot-randomised-study
#8
Boon Eu Andrew Kwek, Tiing Leong Ang, Peng Lan Jeannie Ong, Yi Lyn Jessica Tan, Shih Wen Daphne Ang, Ngai Moh Law, Prem Harichander Thurairajah, Kwong Ming Fock
BACKGROUND: Preliminary studies on a new topical hemostatic agent TC-325 show its safety and effectiveness in the treatment of active upper GI bleeding. However, to date, there are no randomized trials comparing Hemospray with the combined conventional technique (CCT). Our pilot study aimed to compare the efficacy and safety of Hemospray with that of the CCT in treating peptic ulcers with active bleeding or high-risk stigmata. METHOD: This was a randomized comparative study of patients with upper GI bleeding symptoms and had Forrest class I, IIA or IIB ulcers...
May 9, 2017: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/28484732/use-of-over-the-scope-clips-otsc-for-hemostasis-in-gastrointestinal-bleeding-in-patients-under-antithrombotic-therapy
#9
Regina Lamberts, Anna Koch, Christian Binner, Marcus Zachäus, Ingrid Knigge, Mark Bernhardt, Ulrich Halm
Background and study aims In patients taking different regimens of antithrombotic and/or anticoagulant therapy, endoscopic management of gastrointestinal bleeding represents a major challenge due to failing endogenous hemostasis. In this retrospective study we report on success rates with the over-the-scope clip (OTSC) system in upper and lower gastrointestinal bleeding in this high-risk patient population. Patients and methods Between February 2011 and June 2014, 75 patients were treated with an OTSC for active gastrointestinal bleeding...
May 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/28483303/transcatheter-arterial-embolization-for-gastrointestinal-bleeding-associated-with-gastric-carcinoma-prognostic-factors-predicting-successful-hemostasis-and%C3%A2-survival
#10
Sangik Park, Ji Hoon Shin, Dong-Il Gwon, Hyoung Jung Kim, Kyu-Bo Sung, Hyun-Ki Yoon, Gi-Young Ko, Heung Kyu Ko
PURPOSE: To evaluate outcomes of transcatheter arterial embolization (TAE) for gastric cancer-related gastrointestinal (GI) bleeding and factors associated with successful TAE and improved survival after TAE. MATERIALS AND METHODS: This retrospective study included 43 patients (34 men; age 60.6 y ± 13.6) with gastric cancer-related GI bleeding undergoing angiography between January 2000 and December 2015. Clinical course, laboratory findings, and TAE characteristics were reviewed...
May 5, 2017: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/28472195/safety-of-endoscopy-in-cancer-patients-on-antiangiogenic-agents-a-retrospective-multicenter-outcomes-study
#11
Toufic Kachaamy, Digant Gupta, Persis Edwin, Pankaj Vashi
BACKGROUND/AIMS: The use of antiangiogenic agents (AAs) in cancer treatment has increased because they offer survival benefit in combination with cytotoxic chemotherapy. Given their potential to cause gastrointestinal (GI) perforation and bleeding, it is currently recommended that AAs be held for 28 days before and after surgery. However, there are no specific guidelines which address their use around endoscopic procedures because data regarding the safety of endoscopy in cancer patients while on AAs is scarce despite the fact that these patients often require endoscopy...
2017: PloS One
https://www.readbyqxmd.com/read/28461094/esophageal-dilation-with-either-bougie-or-balloon-technique-as-a-treatment-for-eosinophilic-esophagitis-a-systematic-review-and-meta-analysis
#12
REVIEW
Michael Dougherty, Thomas M Runge, Swathi Eluri, Evan S Dellon
BACKGROUND AND AIMS: Esophageal dilation is a now recognized to be an important therapeutic modality in eosinophilic esophagitis (EoE). We aimed to evaluate the safety of esophageal dilation in EoE, especially regarding perforation risk, and to examine perforation risk by dilator type. METHODS: We conducted a systematic review of the published literature from January 1, 1950 to June 30, 2016 using Pubmed, EMBASE, and Web of Science. Studies were included if they described patients with EoE who underwent esophageal dilation and also reported the presence or absence of at least 1 adverse event (eg, perforation, bleeding, pain, or hospitalization)...
April 28, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28458597/gastrointestinal-involvement-of-recurrent-renal-cell-carcinoma-ct-findings-and-clinicopathologic-features
#13
Hyo Jung Park, Hyun Jin Kim, Seong Ho Park, Jong Seok Lee, Ah Young Kim, Hyun Kwon Ha
OBJECTIVE: To retrospectively evaluate the CT findings and clinicopathologic features in patients with gastrointestinal (GI) involvement of recurrent renal cell carcinoma (RCC). MATERIALS AND METHODS: The medical records were reviewed for 15 patients with 19 pathologically proven GI tract metastases of RCC. The CT findings were analyzed to determine the involved sites and type of involvement; lesion size, morphology, and contrast enhancement pattern; and occurrence of lymphadenopathy, ascites and other complications...
May 2017: Korean Journal of Radiology: Official Journal of the Korean Radiological Society
https://www.readbyqxmd.com/read/28458008/risk-of-gastrointestinal-bleeding-in-patients-taking-non-vitamin-k-antagonist-oral-anticoagulants-a-systematic-review-and-meta-analysis
#14
Corey S Miller, Alastair Dorreen, Myriam Martel, Thao Huynh, Alan N Barkun
BACKGROUND AND AIMS: Non-vitamin K antagonist oral anticoagulants (NOACs) are convenient and effective in prevention and treatment of venous thromboembolism and prevention of stroke in patients with atrial fibrillation. However, these drugs have been associated with increased risk of gastrointestinal (GI) bleeding. We conducted a systematic review and meta-analysis to determine the risk of GI bleeding in patients receiving these drugs. METHODS: We searched the EMBASE, Medline, Cochrane, and ISI Web of knowledge databases through January 2016 for randomized trials that compared NOACs to conventional anticoagulants for approved indications...
April 27, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28437000/magnetically-guided-capsule-endoscopy
#15
REVIEW
Naveen Shamsudhin, Vladimir I Zverev, Henrik Keller, Salvador Pane, Peter W Egolf, Bradley J Nelson, Alexander M Tishin
Wireless capsule endoscopy (WCE) is a powerful tool for medical screening and diagnosis, where a small capsule is swallowed and moved by means of natural peristalsis and gravity through the human gastrointestinal (GI) tract. The camera-integrated capsule allows for visualization of the small intestine, a region which was previously inaccessible to classical flexible endoscopy. As a diagnostic tool, it allows to localize the sources of bleedings in the middle-part of the gastrointestinal tract and to identify diseases such as inflammatory bowel disease (Crohn's disease), Polyposis-Syndrome and tumors...
April 24, 2017: Medical Physics
https://www.readbyqxmd.com/read/28429894/cytokine-and-metalloproteinases-in-gingival-fluid-from-patients-with-chronic-periodontitis
#16
Laura A Escalona, Patrizzia Mastromatteo-Alberga, María Correnti
The purpose of the present research was to determine the levels of IL- 1a, IL- 1 P, TNF-a, IL-6, IL-6sR, IL-8, IL-10, MMP-3 and EMP-8 in gingival crevicular fluid (GCF) of subjects with chronic periodontitis. Clinical measurements were carried out in 20 patients with chronic periodontitis and 11 periodontally healthy controls. The clinical indexes evalua- ted were: gingival index (GI), plaque index (PI), bleeding on probing (BOP), probing depth (PD) and clinical attachment loss (CAL); the measurements were taken at six sites per tooth in all teeth in each subject...
June 2016: Investigación Clínica
https://www.readbyqxmd.com/read/28427824/association-between-monocyte-chemoattractant-protein-1-2518-a-g-gene-polymorphism-and-the-outcome-of-the-nonsurgical-periodontal-treatment
#17
Ching-Wen Chang, Hsiu-Hui Lin, Shih-Yun Wu, Ching-Yi Wu, Yu-Lin Lai, Shan-Ling Hung
BACKGROUND/PURPOSE: Elevated monocyte chemoattractant protein-1 (MCP-1) is related to severe periodontal destruction. Furthermore, MCP-1 -2518 A/G gene polymorphism affects MCP-1 after inflammatory stimuli. This study analyzed the association between MCP-1 -2518 gene polymorphism and the outcome of nonsurgical periodontal treatment. METHODS: Forty periodontal patients were recruited and MCP-1 -2518 A/G gene polymorphisms were analyzed using polymerase chain reaction-restriction fragment length polymorphism assay...
April 17, 2017: Journal of the Formosan Medical Association, Taiwan Yi Zhi
https://www.readbyqxmd.com/read/28421109/bleeding-meckel-s-diverticulum-in-children-the-diagnostic-value-of-double-balloon-enteroscopy
#18
Lan-Lan Geng, Pei-Yu Chen, Qiang Wu, Hui-Wen Li, Ding-You Li, Min Yang, Si-Tang Gong
Background. Meckel's diverticulum (MD) is the most common congenital anomaly of the gastrointestinal tract. The purpose of this study was to evaluate the diagnostic value and safety of double-balloon enteroscopy (DBE) for bleeding MD in children. Methods. We included consecutive children who were highly suspected of MD between 2012 and 2013. All patients underwent Meckel's scan. DBE was performed for patient with negative Meckel's scan. An exploratory laparoscopy was performed in children with positive Meckel's scan or DBE...
2017: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/28418549/glasgow-blatchford-score-predicted-intervention-or-death-better-than-4-other-prediction-models-in-upper-gi-bleeding
#19
Nicholas Talley, Michael Potter
No abstract text is available yet for this article.
April 18, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/28414670/diulafoy-s-lesion-an-uncanny-etiology-of-gastrointestinal-bleed
#20
V Gasia, O Lamendola
INTRODUCTION: Dieulafoy's lesion is a relatively rare, but potentially life-threatening, condition. It accounts for 1-2 percent of acute gastrointestinal (GI); bleeding. CASE: A 99-year-old woman was initially admitted due to left lower extremity cellulitis related to chronic venous stasis ulcer and was receiving broad-spectrum IV antibiotics. Upon admission to the medical floor, she had an episode of hematemesis and multiple bowel movements with black-tarry stools...
March 2017: Journal of the Louisiana State Medical Society: Official Organ of the Louisiana State Medical Society
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