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https://www.readbyqxmd.com/read/29333915/gaze-avoidance-and-perseverative-language-in-fragile-x-syndrome-and-autism-spectrum-disorder-brief-report
#1
Laura Friedman, Audra Sterling, Andrea Barton-Hulsey
Gaze avoidance and perseverative language impact pragmatics in autism spectrum disorder (ASD) and fragile X syndrome (FXS). We examined these features during conversation samples in boys with ASD (n = 10) and boys with FXS and ASD (FXS+ASD; n = 10). Both groups had similar high rates of gaze avoidance and topic and conversation device perseverations, yet these features were not correlated with one another. Boys with FXS+ASD produced a higher proportion of single utterance perseverations. Results from this study highlight the need for future research to identify potential mechanisms influencing the presence of language perseverations and gaze avoidance...
January 15, 2018: Developmental Neurorehabilitation
https://www.readbyqxmd.com/read/29331979/now-you-see-me-a-pragmatic-cohort-study-comparing-first-and-final-radiological-diagnoses-in-the-emergency-department
#2
Björn Mattsson, David Ertman, Aristomenis Konstantinos Exadaktylos, Luca Martinolli, Wolf E Hautz
OBJECTIVES: To (1) compare timely but preliminary and definitive but delayed radiological reports in a large urban level 1 trauma centre, (2) assess the clinical significance of their differences and (3) identify clinical predictors of such differences. DESIGN, SETTING AND PARTICIPANTS: We performed a retrospective record review for all 2914 patients who presented to our university affiliated emergency department (ED) during a 6-week period. In those that underwent radiological imaging, we compared the patients' discharge letter from the ED to the definitive radiological report...
January 13, 2018: BMJ Open
https://www.readbyqxmd.com/read/29331971/a-study-protocol-for-a-non-randomised-comparison-trial-evaluating-the-feasibility-and-effectiveness-of-a-mobile-cognitive-behavioural-programme-with-integrated-coaching-for-anxious-adults-in-primary-care
#3
Eva Szigethy, Francis Solano, Meredith Wallace, Dina L Perry, Lauren Morrell, Kathryn Scott, Megan Jones Bell, Megan Oser
INTRODUCTION: Generalised anxiety disorder (GAD) and subclinical GAD are highly prevalent in primary care. Unmanaged anxiety worsens quality of life in patients seen in primary care practices and leads to increased medical utilisation and costs. Programmes that teach patients cognitive-behavioural therapy (CBT) techniques have been shown to improve anxiety and to prevent the evolution of anxiety symptoms to disorders, but access and engagement have hampered integration of CBT into medical settings...
January 13, 2018: BMJ Open
https://www.readbyqxmd.com/read/29331656/effect-of-a-wearable-patient-sensor-on-care-delivery-for-preventing-pressure-injuries-in-acutely-ill-adults-a-pragmatic-randomized-clinical-trial-ls-hapi-study
#4
David Pickham, Nic Berte, Mike Pihulic, Andre Valdez, Barbara Mayer, Manisha Desai
IMPORTANCE: Though theoretically sound, studies have failed to demonstrate the benefit of routine repositioning of at-risk patients for the prevention of hospital acquired pressure injuries. OBJECTIVE: To assess the clinical effectiveness of a wearable patient sensor to improve care delivery and patient outcomes by increasing the total time with turning compliance and preventing pressure injuries in acutely ill patients. DESIGN: Pragmatic, investigator initiated, open label, single site, randomized clinical trial...
December 30, 2017: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/29330835/international-guidelines-for-groin-hernia-management
#5
(no author information available yet)
INTRODUCTION: Worldwide, more than 20 million patients undergo groin hernia repair annually. The many different approaches, treatment indications and a significant array of techniques for groin hernia repair warrant guidelines to standardize care, minimize complications, and improve results. The main goal of these guidelines is to improve patient outcomes, specifically to decrease recurrence rates and reduce chronic pain, the most frequent problems following groin hernia repair. They have been endorsed by all five continental hernia societies, the International Endo Hernia Society and the European Association for Endoscopic Surgery...
January 12, 2018: Hernia: the Journal of Hernias and Abdominal Wall Surgery
https://www.readbyqxmd.com/read/29330101/telephone-based-weight-loss-support-for-patients-with-knee-osteoarthritis-a-pragmatic-randomized-controlled-trial
#6
Kate M O'Brien, John Wiggers, Amanda Williams, Elizabeth Campbell, Rebecca K Hodder, Luke Wolfenden, Sze Lin Yoong, Emma K Robson, Robin Haskins, Steven J Kamper, Chris Rissel, Christopher M Williams
OBJECTIVE: To determine the effectiveness of telephone-based weight loss support in reducing the intensity of knee pain in patients with knee osteoarthritis, who are overweight or obese, compared to usual care. DESIGN: We conducted a parallel randomized controlled trial (RCT), embedded within a cohort multiple RCT of patients on a waiting list for outpatient orthopaedic consultation at a tertiary referral hospital in NSW, Australia. Patients with knee osteoarthritis, classified as overweight or obese (body mass index between ≥27kg/m2 and <40kg/m2) were randomly allocated to receive referral to an existing non-disease specific government funded 6-month telephone-based weight management and healthy lifestyle service or usual care...
January 9, 2018: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/29329395/open-access-physical-activity-programs-for-older-adults-a-pragmatic-and-systematic-review
#7
Laura E Balis, Thomas Strayer, NithyaPriya Ramalingam, Meghan Wilson, Samantha M Harden
Background and Objectives: Open-access, community-based programs are recommended to assist older adults in meeting physical activity guidelines, but the characteristics, impact, and scalability of these programs is less understood. The Land-Grant University Cooperative Extension System, an organization providing education through county-based educators, functions as a delivery system for these programs. A systematic review was conducted to determine characteristics of effective older adult physical activity programs and the extent to which programs delivered in Extension employ these characteristics...
January 10, 2018: Gerontologist
https://www.readbyqxmd.com/read/29329226/plils-a-practical-indoor-localization-system-through-less-expensive-wireless-chips-via-subregion-clustering
#8
Xiaolong Li, Yifu Yang, Jun Cai, Yun Deng, Junfeng Yang, Xinmin Zhou, Lina Tan
Reducing costs is a pragmatic method for promoting the widespread usage of indoor localization technology. Conventional indoor localization systems (ILSs) exploit relatively expensive wireless chips to measure received signal strength for positioning. Our work is based on a cheap and widely-used commercial off-the-shelf (COTS) wireless chip, i.e., the Nordic Semiconductor nRF24LE1, which has only several output power levels, and proposes a new power level based-ILS, called Plils. The localization procedure incorporates two phases: an offline training phase and an online localization phase...
January 12, 2018: Sensors
https://www.readbyqxmd.com/read/29328742/pragmatic-recycling-of-paper-and-cardboard-in-the-operating-theatre-an-audit
#9
Douglas Ra McKendrick, Lorraine J Snedden, Rozel Bunch, Hazel McGregor
Despite recent legislation introduced in Scotland and motivated recycling at home, very little recycling exists within theatre environments. This study audited the introduction of recycling of paper and cardboard. All waste within a single operating theatre was collected by a dedicated team for 20 surgical cases. The collection of clean paper and cardboard packaging was limited to the theatre preparation room (TPR) and anaesthetic room (AR). No waste segregation was attempted within the operating theatre itself...
March 2017: Journal of Perioperative Practice
https://www.readbyqxmd.com/read/29327211/twelve-lessons-learned-for-effective-research-partnerships-between-patients-caregivers-clinicians-academic-researchers-and-other-stakeholders
#10
Holly O Witteman, Selma Chipenda Dansokho, Heather Colquhoun, Angela Fagerlin, Anik M C Giguere, Sholom Glouberman, Lynne Haslett, Aubri Hoffman, Noah M Ivers, France Légaré, Jean Légaré, Carrie A Levin, Karli Lopez, Victor M Montori, Jean-Sébastien Renaud, Kerri Sparling, Dawn Stacey, Robert J Volk
Research increasingly means that patients, caregivers, health professionals, other stakeholders, and academic investigators work in partnership. This requires effective collaboration rooted in mutual respect, involvement of all participants, and good communication. Having conducted such partnered research over multiple projects, and having recently completed a project together funded by the Patient-Centered Outcomes Research Institute, we collaboratively developed a list of 12 lessons we have learned about how to ensure effective research partnerships...
January 4, 2018: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/29325913/efficacy-of-a-web-based-oral-case-presentation-instruction-module-a-multi-center-randomized-controlled-trial
#11
Colin M Sox, Rebecca Tenney-Soeiro, Linda O Lewin, Jeanine Ronan, Mary Brown, Marta King, Rachel Thompson, Michelle Noelck, Jamie S Sutherell, Michael Silverstein, Howard J Cabral, Michael Dell
OBJECTIVE: Effective self-directed educational tools are invaluable. Our objective was to determine whether a self-directed, web-based oral case presentation module would 1) improve medical students' oral case presentations compared to usual curriculum 2) with similar efficacy as structured oral presentation faculty feedback sessions. METHODS: We conducted a pragmatic multi-center cluster randomized controlled trial among medical students rotating in pediatric clerkships at seven U...
January 8, 2018: Academic Pediatrics
https://www.readbyqxmd.com/read/29325593/evaluating-the-long-term-impact-of-the-fostering-changes-training-programme-for-foster-carers-in-wales-the-confidence-in-care-trial-study-protocol-for-a-randomised-controlled-trial
#12
Gwenllian Moody, Lucy Brookes-Howell, Rebecca Cannings-John, Sue Channon, Elinor Coulman, Mandy Lau, Alyson Rees, Jonathan Scourfield, Jeremy Segrott, Michael Robling
BACKGROUND: The Fostering Changes programme was developed by the Adoption and Fostering National Team at the Maudsley Hospital, South London, in conjunction with King's College London. It is a 12-week group-based training programme for foster and kin carers, which aims to build positive relationships between carers and children, encourage positive child behaviour and set appropriate limits, through a practical skills-based approach. The programme also aims to improve foster carers' understanding of the causes of children's social and emotional difficulties and their confidence in applying this knowledge in various situations...
January 11, 2018: Trials
https://www.readbyqxmd.com/read/29325575/routinely-collected-data-for-randomized-trials-promises-barriers-and-implications
#13
REVIEW
Kimberly A Mc Cord, Rustam Al-Shahi Salman, Shaun Treweek, Heidi Gardner, Daniel Strech, William Whiteley, John P A Ioannidis, Lars G Hemkens
BACKGROUND: Routinely collected health data (RCD) are increasingly used for randomized controlled trials (RCTs). This can provide three major benefits: increasing value through better feasibility (reducing costs, time, and resources), expanding the research agenda (performing trials for research questions otherwise not amenable to trials), and offering novel design and data collection options (e.g., point-of-care trials and other designs directly embedded in routine care). However, numerous hurdles and barriers must be considered pertaining to regulatory, ethical, and data aspects, as well as the costs of setting up the RCD infrastructure...
January 11, 2018: Trials
https://www.readbyqxmd.com/read/29325025/towards-an-understanding-of-resilience-responding-to-health-systems-shocks
#14
Johanna Hanefeld, Susannah Mayhew, Helena Legido-Quigley, Frederick Martineau, Marina Karanikolos, Karl Blanchet, Marco Liverani, Esther Yei Mokuwa, Gillian McKay, Dina Balabanova
The recent outbreak of Ebola Virus Disease (EVD) in West Africa has drawn attention to the role and responsiveness of health systems in the face of shock. It brought into sharp focus the idea that health systems need not only to be stronger but also more 'resilient'. In this article, we argue that responding to shocks is an important aspect of resilience, examining the health system behaviour in the face of four types of contemporary shocks: the financial crisis in Europe from 2008 onwards; climate change disasters; the EVD outbreak in West Africa 2013-16; and the recent refugee and migration crisis in Europe...
January 9, 2018: Health Policy and Planning
https://www.readbyqxmd.com/read/29324477/assuring-quality-for-non-hospital-based-biologic-infusions-in-pediatric-inflammatory-bowel-disease-a-clinical-report-from-the-north-american-society-for-pediatric-gastroenterology-hepatology-and-nutrition
#15
Elaine Barfield, Robbyn Sockolow, Edward Hoffenberg, Shehzad Saeed, Sandra Kim, Leah Siebold, Joseph Picoraro, Jonathan Moses, Dana Dykes, Andrew Grossman, Ghassan Wahbeh, K T Park
The primary aim of this Clinical Report by the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition is to provide formal guidance to pediatric gastroenterologists and clinicians, health systems, and insurance payers regarding home- and office-based infusions for biologic therapies in pediatric inflammatory bowel disease (IBD). Patients in North America are increasingly denied coverage by payers based on "place of service" codes at hospital-based infusion units where the treating clinicians primarily provide care...
January 10, 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29323205/unsupervised-learning-and-pattern-recognition-of-biological-data-structures-with-density-functional-theory-and-machine-learning
#16
Chien-Chang Chen, Hung-Hui Juan, Meng-Yuan Tsai, Henry Horng-Shing Lu
By introducing the methods of machine learning into the density functional theory, we made a detour for the construction of the most probable density function, which can be estimated by learning relevant features from the system of interest. Using the properties of universal functional, the vital core of density functional theory, the most probable cluster numbers and the corresponding cluster boundaries in a studying system can be simultaneously and automatically determined and the plausibility is erected on the Hohenberg-Kohn theorems...
January 11, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29322939/public-health-psychopharmacology-a-new-research-discipline-comes-of-age
#17
C Barbui, G Ostuzzi, B Godman
Research evidence guiding the identification of pragmatic and effective actions aimed at improving the selection, availability, affordability and rational prescribing of medicines for mental disorders is sparse and inconsistent. In order to boost the development of new research, in this commentary we suggest to organise and classify all the activities in this area under a common theoretical framework and nomenclature, adopting the term 'public health psychopharmacology'. Public health psychopharmacology is proposed as a research discipline, based on contributions from the fields of regulatory science, health services research and implementation science...
February 2018: Epidemiology and Psychiatric Sciences
https://www.readbyqxmd.com/read/29322163/pragmatic-psychiatric-epidemiology-if-you-can-t-count-it-it-won-t-count
#18
John J McGrath, Preben Bo Mortensen, Harvey A Whiteford
No abstract text is available yet for this article.
January 10, 2018: JAMA Psychiatry
https://www.readbyqxmd.com/read/29321031/deprescribing-preventive-cardiovascular-medication-in-patients-with-predicted-low-cardiovascular-disease-risk-in-general-practice-the-ecstatic-study-a-cluster-randomised-non-inferiority-trial
#19
Clare H Luymes, Rosalinde K E Poortvliet, Nan van Geloven, Margot W M de Waal, Yvonne M Drewes, Jeanet W Blom, Nynke Smidt, Willem J J Assendelft, Wilbert B van den Hout, Wouter de Ruijter, Mattijs E Numans
BACKGROUND: The use of cardiovascular medication for the primary prevention of cardiovascular disease (CVD) is potentially inappropriate when potential risks outweigh the potential benefits. It is unknown whether deprescribing preventive cardiovascular medication in patients without a strict indication for such medication is safe and cost-effective in general practice. METHODS: In this pragmatic cluster randomised controlled non-inferiority trial, we recruited 46 general practices in the Netherlands...
January 11, 2018: BMC Medicine
https://www.readbyqxmd.com/read/29321008/effects-of-a-culturally-specific-tobacco-cessation-intervention-among-african-american-quitline-enrollees-a-randomized-controlled-trial
#20
Monica Webb Hooper, Kelly Carpenter, Michael Payne, Ken Resnicow
BACKGROUND: African Americans suffer disproportionately from tobacco-related illness and have more difficulty quitting smoking than other racial/ethnic groups. Previous research indicates that African American treatment-seekers are high utilizers of tobacco quitlines, yet cessation rates via quitlines are lower relative to whites. The goal of the present study is to test the effectiveness of adding a culturally specific, video-based, adjunct to standard quitline care. It is hypothesized that the integration of an evidence-based intervention (Pathways to Freedom: Leading the Way to a Smoke-Free Community©; PTF) into quitline services will increase cessation and treatment engagement compared to control conditions, and that effects will be moderated by sociocultural factors (e...
January 10, 2018: BMC Public Health
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