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https://www.readbyqxmd.com/read/29786963/design-and-fabrication-of-printed-paper-based-hybrid-micro-supercapacitor-by-using-graphene-and-redox-active-electrolyte
#1
Bhawna Nagar, Deepak P Dubal, Luis Pires, Arben Merkoçi, Pedro Gómez-Romero
Inspired by future needs of flexible, simple, and low-cost energy storage devices, smart graphene-based micro-supercapacitors on conventional Xerox paper substrates were developed. The use of redox-active species (iodine redox couple) was explored to further improve the paper device's performance. The device based on printed graphene paper itself already had a remarkable maximum volumetric capacitance of 29.6 mF cm-3 (volume of whole device) at 6.5 mA cm-3 . The performance of the hybrid electrode with redox-active potassium iodide at the graphene surface was tested...
May 22, 2018: ChemSusChem
https://www.readbyqxmd.com/read/29786781/the-ejes-3d-tool-for-personalized-prescription-of-exercise-in-axial-spondyloarthritis-through-multimedia-animations-pilot-study
#2
Mariano Tomás Flórez, Raquel Almodóvar, Fernando García Pérez, Ana Belén Rodríguez Cambrón, Loreto Carmona, María Ángeles Pérez Manzanero, Juan Aboitiz Cantalapiedra, Ana Urruticoechea-Arana, Carlos J Rodríguez Lozano, Carmen Castro, Cristina Fernández-Carballido, Eugenio de Miguel, Eva Galíndez, José Luis Álvarez Vega, Juan Carlos Torre Alonso, Luis F Linares, Mireia Moreno, Victoria Navarro-Compán, Xavier Juanola, Pedro Zarco
To develop and evaluate a web application based on multimedia animations, combined with a training program, to improve the prescription of exercises in spondyloarthritis (SpA). After a review of exercises included in the main clinical trials and recommendations of international societies, a multidisciplinary team-rehabilitators, rheumatologists, physiotherapists, computer scientists and graphic designers-developed a web application for the prescription of exercises (EJES-3D). Once completed, this was presented to 12 pairs of rehabilitators-rheumatologists from the same hospital in a workshop...
May 21, 2018: Rheumatology International
https://www.readbyqxmd.com/read/29786739/synthesis-of-pure-silica-mfi-zeolites-using-imidazolium-based-long-dications-a-comparative-study-of-structure-directing-effects-derived-from-a-further-spacer-length-increase
#3
Peng Lu, Luis Gómez-Hortigüela, Miguel A Camblor
Length-dependent structure direction of linear methylimidazolium-based dications towards MFI zeolite, previously known only for the tetramethylene spacer, has also been found for octamethylene and decamethylene spacers. This works only under highly concentrated conditions, whereas dilution always tends to favor TON, a default structure that is the only zeolite obtained with the other reported dications (with tri-, penta-, and hexamethylene spacers). The locations and conformations of the dications have been studied by molecular mechanics simulations...
May 22, 2018: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/29786736/phase-behaviour-and-applications-of-a-binary-liquid-mixture-of-methanol-and-a-thermotropic-liquid-crystal
#4
Luis A Serrano, Maximiliano J Fornerod, Ye Yang, Simon Gaisford, Francesco Stellacci, Stefan Guldin
Herein, we report on the phase behaviour of a binary liquid mixture composed of methanol (MeOH) and the thermotropic liquid crystal 4-cyano-4'-pentylbiphenyl (5CB). The corresponding phase diagram combines features of a conventional liquid-liquid mixture with characteristics that are particular to the nematic liquid crystal. We observe four arrangements as a function of composition and temperature, namely monophasic isotropic, monophasic nematic, biphasic isotropic-isotropic and biphasic isotropic-nematic, with an upper critical solution temperature of 24...
May 22, 2018: Soft Matter
https://www.readbyqxmd.com/read/29786519/effect-of-vaccination-on-cattle-subclinically-infected-with-foot-and-mouth-disease-virus-in-cameroon
#5
Miranda R Bertram, Amy Delgado, Steven J Pauszek, George R Smoliga, Barbara Brito, Carolina Stenfeldt, Ethan J Hartwig, Simon Dickmu Jumbo, Mamoudou Abdoulmoumini, Amba Abona Oliva Marie, Robert Salhine, Luis L Rodriguez, Rebecca Garabed, Jonathan Arzt
Foot-and-mouth disease (FMD) is one of the most contagious and economically important livestock diseases worldwide. Four serotypes of FMD virus (FMDV; O, A, SAT1, SAT2) circulate in Cameroon, and a trivalent inactivated vaccine against the three most common serotypes (O, A, SAT2) was recently introduced in 2014. The objective of this study was to characterize vaccine performance in cattle under natural hyperendemic conditions in the Adamawa region of Cameroon. Vaccinated cattle (n = 50) and non-vaccinated controls (n = 100) were monitored by serum and oropharyngeal fluid (OPF) sample collection through a 12-month period...
July 1, 2018: Preventive Veterinary Medicine
https://www.readbyqxmd.com/read/29786424/tuning-gene-activity-by-inducible-and-targeted-regulation-of-gene-expression-in-minimal-bacterial-cells
#6
Ana M Mariscal, Shigeyuki Kakizawa, Jonathan Y Hsu, Kazuki Tanaka, Luis González-González, Alicia Broto, Enrique Querol, Maria Lluch-Senar, Carlos Piñero-Lambea, Lijie Sun, Philip D Weyman, Kim S Wise, Chuck Merryman, Gavin Tse, Adam J Moore, Clyde A Hutchison, Hamilton O Smith, Masaru Tomita, J Craig Venter, John I Glass, Jaume Piñol, Yo Suzuki
Functional genomics studies in minimal mycoplasma cells enable unobstructed access to some of the most fundamental processes in biology. Conventional transposon bombardment and gene knockout approaches often fail to reveal functions of genes that are essential for viability, where lethality precludes phenotypic characterization. Conditional inactivation of genes is effective for characterizing functions central to cell growth and division, but tools are limited for this purpose in mycoplasmas. Here we demonstrate systems for inducible repression of gene expression based on clustered regularly interspaced short palindromic repeats-mediated interference (CRISPRi) in Mycoplasma pneumoniae and synthetic Mycoplasma mycoides, two organisms with reduced genomes actively used in systems biology studies...
May 22, 2018: ACS Synthetic Biology
https://www.readbyqxmd.com/read/29785870/micrornas-and-response-to-statins-in-patients-with-hypercholesterolemia-from-basic-research-to-precision-medicine
#7
Tomás Zambrano, Luis A Salazar
No abstract text is available yet for this article.
May 22, 2018: Pharmacogenomics
https://www.readbyqxmd.com/read/29785766/schizophyllum-commune-an-unexploited-source-for-lignocellulose-degrading-enzymes
#8
REVIEW
Omar Eduardo Tovar-Herrera, Adriana Mayrel Martha-Paz, Yordanis Pérez-LLano, Elisabet Aranda, Juan Enrique Tacoronte-Morales, María Teresa Pedroso-Cabrera, Katiushka Arévalo-Niño, Jorge Luis Folch-Mallol, Ramón Alberto Batista-García
Lignocellulose represents the most abundant source of carbon in the Earth. Thus, fraction technology of the biomass turns up as an emerging technology for the development of biorefineries. Saccharification and fermentation processes require the formulation of enzymatic cocktails or the development of microorganisms (naturally or genetically modified) with the appropriate toolbox to produce a cost-effective fermentation technology. Therefore, the search for microorganisms capable of developing effective cellulose hydrolysis represents one of the main challenges in this era...
May 21, 2018: MicrobiologyOpen
https://www.readbyqxmd.com/read/29785709/four-year-follow-up-of-a-single-arm-phase-ii-clinical-trial-of-ibrutinib-with-rituximab-ir-in-patients-with-relapsed-refractory-mantle-cell-lymphoma-mcl
#9
Preetesh Jain, Jorge Romaguera, Samer A Srour, Hun J Lee, Frederick Hagemeister, Jason Westin, Luis Fayad, Felipe Samaniego, Maria Badillo, Liang Zhang, Lorreta Nastoupil, Rashmi Kanagal-Shamanna, Nathan Fowler, Michael L Wang
Ibrutinib has shown significant activity in patients with relapsed or refractory mantle cell lymphoma (RR-MCL). We report the long-term outcome and safety profile of a single-centre, single arm, open-label, phase 2 study of RR-MCL treated with IR. Overall, the median follow-up time was 47 months (range 1-52 months), median duration on treatment was 16 months (range 1-53 months) and median number of treatment cycles was 17 (range 1-56). Twenty-nine patients (58%) achieved complete remission and of these, 12 patients continue on study...
May 22, 2018: British Journal of Haematology
https://www.readbyqxmd.com/read/29785475/cohort-study-of-psychiatric-adverse-events-following-exposure-to-levonorgestrel-containing-intrauterine-devices-in-uk-general-practice
#10
Jim Slattery, Daniel Morales, Luis Pinheiro, Xavier Kurz
INTRODUCTION: Intrauterine devices are implantable contraceptives of which some brands steadily release levonorgestrel over an extended time period. Exposure to a levonorgestrel-releasing intrauterine device has been associated with depression and, more recently, a connection to anxiety, panic attacks, sleep problems and restlessness has been suggested. This study uses data from the THIN database of UK general practice to investigate these suggestions. METHODS: A cohort study was performed to compare the incidence of psychiatric adverse events between groups of women who were new users of levonorgestrel-releasing and non-hormonal intrauterine devices...
May 21, 2018: Drug Safety: An International Journal of Medical Toxicology and Drug Experience
https://www.readbyqxmd.com/read/29785371/case-report-clitoromegaly-as-a-consequence-of-congenital-adrenal-hyperplasia-an-accurate-medical-and-surgical-approach
#11
Augusto Rafael Fernandez-Aristi, Andre Alonso Taco-Masias, Luis Montesinos-Baca
We present a case of a woman with a history of Congenital Adrenal Hyperplasia (CAH) diagnosed at the age of 12, who was referred to our unit for surgical treatment. Despite the initial diagnosis was an indirect inguinal hernia, it was a misdiagnosis. Once in our service, this was corrected into clitoromegaly secondary to CAH. Physical examination and imaging test discarded other abnormalities, such as secondary effects androgenization. Regarding surgical treatment, the techniques used were Spencer and Allen combined with Kumar, which are the most used for clitoroplasty but also less used in Peru...
May 2018: Urology Case Reports
https://www.readbyqxmd.com/read/29785357/prognostic-significance-of-cyclins-a2-b1-d1-and-e1-and-ccnd1-numerical-aberrations-in-oral-squamous-cell-carcinomas
#12
Luís Silva Monteiro, Márcio Diniz-Freitas, Saman Warnakulasuriya, Tomás Garcia-Caballero, Jerónimo Forteza-Vila, Máximo Fraga
We analysed the expression of cyclins A2, B1, D1, and E1 by immunohistochemistry and numerical aberrations in CCND1 gene by fluorescence in situ hybridization technique in 67 primary oral squamous cell carcinomas (OSCC). Cyclin A2 expression was observed in 54 (83.1%) tumours, cyclin D1 in 58 (89.2%), cyclin B1 in 39 (60%), and cyclin E in 21 (32.8%). CCND1 region analysis revealed 26 (43.3%) tumours with the presence of numerical aberrations which were correlated with cyclin D1 high expression (Rho = 0...
2018: Analytical Cellular Pathology (Amsterdam)
https://www.readbyqxmd.com/read/29785342/occurrence-of-termites-isoptera-on-living-and-standing-dead-trees-in-a-tropical-dry-forest-in-mexico
#13
Nancy Calderón-Cortés, Luis H Escalera-Vázquez, Ken Oyama
Termites play a key role as ecosystem engineers in numerous ecological processes though their role in the dynamics of wood degradation in tropical dry forests, particularly at the level of the crown canopy, has been little studied. In this study, we analysed the occurrence of termites in the forest canopy by evaluating the density and proportion of living and standing dead trees associated with termites in deciduous and riparian habitats of the tropical dry forest in Chamela, Mexico. The results indicated that 60-98% of standing dead trees and 23-59% of living trees in Chamela were associated with termites...
2018: PeerJ
https://www.readbyqxmd.com/read/29785295/uniportal-video-assisted-thoracoscopic-segmentectomy
#14
Luis Angel Hernandez-Arenas, Rushmi D Purmessur, Diego Gonzalez-Rivas
Uniportal video-assisted thoracoscopic surgery (VATS) segmentectomy is a technically more complex procedure than uniportal VATS lobectomy, since a detailed comprehension of the segmental anatomy is required. Anatomic sublobar resection can achieve outcomes equivalent to lobectomy in selected patients with stage IA non-small cell lung carcinoma (NSCLC). In this paper we describe our clinical experiences and introduce the technical details of uniportal VATS segmentectomy, including expertise advice ("tips and tricks") in patient selection, positioning and incisions and technical highlights of the most common types of segmentectomies...
April 2018: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29785268/impact-of-fullerene-derivative-isomeric-purity-on-the-performance-of-inverted-planar-perovskite-solar-cells
#15
Edison Castro, Gerardo Zavala, Sairaman Seetharaman, Francis D'Souza, Luis Echegoyen
The effect of utilizing a pure cis -α-dimethoxy carbonyl fulleropyrrolidine C70 (DMEC70 ) isomer as the electron transporting material (ETM) in inverted perovskite solar cells (PSCs) was evaluated. The as-prepared C70 mono-adduct products are mixtures of regioisomers and the interest was to evaluate them independently as ETMs. Three different cis -DMEC70 isomers (α, β- endo and β- exo ) (mix-DMEC70 ) were synthesized and purified by HPLC. It was found that PSCs based on the pure α-DMEC70 exhibit a substantially enhanced maximum power conversion efficiency (PCE) of 18...
September 28, 2017: Journal of Materials Chemistry. A, Materials for Energy and Sustainability
https://www.readbyqxmd.com/read/29785202/opto-thermoelectric-nanotweezers
#16
Linhan Lin, Mingsong Wang, Xiaolei Peng, Emanuel N Lissek, Zhangming Mao, Leonardo Scarabelli, Emily Adkins, Sahin Coskun, Husnu Emrah Unalan, Brian A Korgel, Luis M Liz-Marzán, Ernst-Ludwig Florin, Yuebing Zheng
Optical manipulation of plasmonic nanoparticles provides opportunities for fundamental and technical innovation in nanophotonics. Optical heating arising from the photon-to-phonon conversion is considered as an intrinsic loss in metal nanoparticles, which limits their applications. We show here that this drawback can be turned into an advantage, by developing an extremely low-power optical tweezing technique, termed opto-thermoelectric nanotweezers (OTENT). Through optically heating a thermoplasmonic substrate, alight-directed thermoelectric field can be generated due to spatial separation of dissolved ions within the heating laser spot, which allows us to manipulate metal nanoparticles of a wide range of materials, sizes and shapes with single-particle resolution...
April 2018: Nature Photonics
https://www.readbyqxmd.com/read/29785138/a-review-of-soft-tissue-sarcomas-translation-of-biological-advances-into-treatment-measures
#17
REVIEW
Ngoc T Hoang, Luis A Acevedo, Michael J Mann, Bhairavi Tolani
Soft-tissue sarcomas are rare malignant tumors arising from connective tissues and have an overall incidence of about five per 100,000 per year. While this diverse family of malignancies comprises over 100 histological subtypes and many molecular aberrations are prevalent within specific sarcomas, very few are therapeutically targeted. Instead of utilizing molecular signatures, first-line sarcoma treatment options are still limited to traditional surgery and chemotherapy, and many of the latter remain largely ineffective and are plagued by disease resistance...
2018: Cancer Management and Research
https://www.readbyqxmd.com/read/29784781/c-4-sterol-demethylation-enzymes-distinguish-bacterial-and-eukaryotic-sterol-synthesis
#18
Alysha K Lee, Amy B Banta, Jeremy H Wei, David J Kiemle, Ju Feng, José-Luis Giner, Paula V Welander
Sterols are essential eukaryotic lipids that are required for a variety of physiological roles. The diagenetic products of sterol lipids, sterane hydrocarbons, are preserved in ancient sedimentary rocks and are utilized as geological biomarkers, indicating the presence of both eukaryotes and oxic environments throughout Earth's history. However, a few bacterial species are also known to produce sterols, bringing into question the significance of bacterial sterol synthesis for our interpretation of sterane biomarkers...
May 21, 2018: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29784681/use-of-intracardiac-echocardiography-in-interventional-cardiology-working-with-the-anatomy-rather-than-fighting-it
#19
REVIEW
Andres Enriquez, Luis C Saenz, Raphael Rosso, Frank E Silvestry, David Callans, Francis E Marchlinski, Fermin Garcia
The indications for catheter-based structural and electrophysiological procedures have recently expanded to more complex scenarios, in which an accurate definition of the variable individual cardiac anatomy is key to obtain optimal results. Intracardiac echocardiography (ICE) is a unique imaging modality able to provide high-resolution real-time visualization of cardiac structures, continuous monitoring of catheter location within the heart, and early recognition of procedural complications, such as pericardial effusion or thrombus formation...
May 22, 2018: Circulation
https://www.readbyqxmd.com/read/29784659/united-states-of-amnesia-rescuing-memory-loss-from-diverse-conditions
#20
EDITORIAL
Clara Ortega-de San Luis, Tomás J Ryan
Amnesia - the loss of memory function - is often the earliest and most persistent symptom of dementia. It occurs as a consequence of a variety of diseases and injuries. These include neurodegenerative, neurological or immune disorders, drug abuse, stroke or head injuries. It has both troubled and fascinated humanity. Philosophers, scientists, physicians and anatomists have all pursued an understanding of how we learn and memorise, and why we forget. In the last few years, the development of memory engram labelling technology has greatly impacted how we can experimentally study memory and its disorders in animals...
May 18, 2018: Disease Models & Mechanisms
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