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https://www.readbyqxmd.com/read/29928613/development-of-a-clinically-relevant-symptom-index-to-assess-patients-with-chronic-orchialgia-chronic-scrotal-content-pain
#1
Alan Scott Polackwich, Hans Chin Arora, Jianbo Li, Laurence Levine, Bayo Tojuola, Sijo Parekattil, Daniel A Shoskes
Background: The purpose of this study was to develop a candidate symptom index for men with an established diagnosis of chronic orchialgia. Methods: Based on interviews with patients and providers, we developed a 70-item questionnaire that focused on seven areas of orchialgia symptoms: pain, location, urinary symptoms, sexual dysfunction, medical history and quality of life (QOL) impact. The questionnaire was completed by patients at two medical centers. Cluster analysis was performed with the software package R (3...
May 2018: Translational Andrology and Urology
https://www.readbyqxmd.com/read/29925936/does-underestimated-penile-size-impact-erectile-function-in-healthy-men
#2
Brunno Cf Sanches, Walker W Laranja, João Cc Alonso, Ronald F Rejowski, Fabiano A Simões, Leonardo O Reis
The aim of this study is to assess the impact of objective (stretched) and subjective penile size in the erectile function in a urological check-up program on a cross-sectional study including 689 men aged 35-70 years. IIEF-5 questionnaire, physical examination (penile length, prostate volume, blood pressure, body mass index-BMI), metabolic syndrome (MS), comorbidities, habits (sexual intercourse frequency, physical activity, alcohol, and tobacco use), level of education, serum glucose, total testosterone, estradiol, PSA, lipid profile, and self-perceptions (ejaculation time and subjective penile size) were examined in multivariate models using logistic and linear regressions...
June 21, 2018: International Journal of Impotence Research
https://www.readbyqxmd.com/read/29923036/a-review-of-male-sexual-health-and-dysfunction-following-surgical-treatment-for-benign-prostatic-hyperplasia-and-lower-urinary-tract-symptoms
#3
REVIEW
Alex Borchert, David A Leavitt
PURPOSE OF REVIEW: Review how the various surgical treatments for benign prostatic hyperplasia and lower urinary tract symptoms impact on male sexual health and function. RECENT FINDINGS: The interplay between benign prostatic hyperplasia and erectile function is complex, and the conditions seem linked. Most cavitating procedures to improve male voiding will degrade ejaculatory and possibly erectile function. Many of the newer minimally invasive therapies appear to preserve sexual function in the short term while sacrificing some of the voiding improvements realized with more complete removal of the prostate adenoma...
June 19, 2018: Current Urology Reports
https://www.readbyqxmd.com/read/29922607/correlation-analysis-of-erectile-dysfunction-with-lower-urinary-tract-symptoms-luts-degree-and-clinical-features-in-luts-patients
#4
Lei Wang, Tongqing Wang, Jian Liu, Jizheng Wang
Background: We aimed to investigate the prevalence of erectile dysfunction (ED) in patients with lower urinary tract symptoms (LUTS) and to explore the correlation of ED with LUTS and its clinical features. Methods: Overall, 400 outpatients and inpatients with LUTS diagnosed in Zhengzhou Central Hospital, Zhengzhou University, Zhengzhou, Henan Province, China from June 2015 to June 2017 were collected. LUTS degree was assessed by the International Prostate Symptom Score (IPSS), and ED degree was assessed by the International Index of Erectile Function (IIEF-5)...
May 2018: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/29921153/prevalence-of-erectile-dysfunction-in-egyptian-males-with-metabolic-syndrome
#5
Mohammed Nader Salama, Ahmed Abulfotooh Eid, Alaa Hatem, Ahmed Kamal Swidan
OBJECTIVES: Determination of the potential effect of metabolic syndrome (MetS) on erectile function in Egyptian men and description of the sociodemographic characteristics of these men. MATERIALS AND METHODS: A cohort of 615 patients presenting to urology department aged between 30 and 75 years were prospectively assessed and divided into two groups. Group I (n = 325) diagnosed with MetS and mean age of 56.07 ± 8.51 years. Group II (n = 290) subjects with no MetS and mean age 54...
June 19, 2018: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/29920249/endothelial-colony-forming-cells-from-human-umbilical-cord-blood-improved-severe-erectile-dysfunction-in-obese-type-ii-diabetic-rats
#6
Abrar Al-Mahmood Siddiquee, P Ganesan Adaikan, Lang Chu Lau, Baharudin Bin Said, Mark Chong, Jerry Chan, Swee Hin Teoh
AIM: To investigate the effect of intracavernous injection of human umbilical cord blood derived endothelial colony forming cells (HUCB ECFCs) on erectile dysfunction (ED) in Zucker Diabetic Fatty (ZDF) rat model. METHODS: Erectile function was assessed by cavernous nerve electrostimulation in ZDF rats aged 20-28 weeks. Following confirmation of severe ED at the age of 28 weeks, 21 ZDF rats were randomly assigned to three experimental groups: 1 million ECFCs, 2 million ECFCs, and phosphate buffered saline (PBS)...
June 16, 2018: Life Sciences
https://www.readbyqxmd.com/read/29917254/erectile-function-and-gonadal-hormones-levels-in-men-with-end-stage-renal-disease-it-s-relevance-to-duration-of-haemodialysis
#7
Abul-Fotouh Ahmed, Mahmoud Shaban, Abdullah Daoud, Nagah Mohamed, Ahmed Solyman, Ahmed Fahim
In this study, we evaluated the relationship between haemodialysis (HD) duration and erectile function status and gonadal hormones serum levels in adult men with end-stage renal disease (ESRD). A total of 118 men with ESRD on chronic HD were eligible for analysis. The erectile dysfunction (ED) was defined and graded according to the international index of erectile function (IIEF-5) score. The serum levels of follicle stimulating hormones (FSH), luteinising hormone (LH), testosterone (TST), prolactin (PRL) and estradiol (E2) were measured using the standard laboratory technique...
June 19, 2018: Andrologia
https://www.readbyqxmd.com/read/29915255/priapism-caused-by-rhino-7-platinum-3000-an-over-the-counter-male-enhancement-supplement
#8
Harsha R Mittakanti, Christopher S Elliott
Male enhancement and erectile dysfunction supplements are typically non-Food and Drug Administration (FDA) approved and readily available for purchase by anyone. Longstanding priapism is a significant potential side effect. A 25-year-old man presented with a 48-h priapism after taking Rhino 7 Platinum 3000. He required bilateral corpo-glanular shunting to alleviate his priapism. On initial 2-week follow-up, he had significant fibrosis of the corporal bodies bilaterally and had been unable to achieve an erection...
June 19, 2018: International Journal of Impotence Research
https://www.readbyqxmd.com/read/29913078/sexual-rehabilitation-after-prostate-cancer-through-assistive-aids-a-comparison-of-gay-bisexual-and-heterosexual-men
#9
Jane M Ussher, Janette Perz, Duncan Rose, Andrew Kellett, Gary Dowsett
The use of assistive aids in sexual rehabilitation after prostate cancer (PCa) was examined in 124 gay, bisexual, and other men who have sex with men (GBM) and 225 heterosexual men. GBM were significantly more likely to use assistive aids (79% versus 56%), to try multiple assistive aids (M = 1.65 versus M = 0.83) including medication, penile injection, penile implant, vacuum pump, and nonmedical sex aids, and to seek information about sexual rehabilitation on the Internet, through counseling, or in a support group...
June 18, 2018: Journal of Sex Research
https://www.readbyqxmd.com/read/29912090/rupture-of-the-corpus-cavernosum-in-a-pediatric-patient
#10
Blake C Gruenberg, David Mortel, Amanda Bogie
Pediatric penile pain is an uncommon complaint and is associated with a wide differential diagnosis including infectious, inflammatory, traumatic, and idiopathic conditions. Penile fractures, anatomically known as rupture of the corpus cavernosum, are almost exclusively reported in sexually mature patients and usually involve forceful manipulation during sexual activity. Rupture of the corpus cavernosum is a true urologic emergency. Failure to recognize and treat rupture of the corpus cavernosum has been associated with residual penile angulation, persistent hematoma, abscess, erectile dysfunction, and fibrosis...
June 14, 2018: Pediatric Emergency Care
https://www.readbyqxmd.com/read/29910163/prostatic-artery-embolization-with-250-%C3%AE-m-spherical-polyzene-coated-hydrogel-microspheres-for-lower-urinary-tract-symptoms-with-follow-up-mr-imaging
#11
Tobias Franiel, René Aschenbach, Sarah Trupp, Thomas Lehmann, Friedrich-Carl von Rundstedt, Marc-Oliver Grimm, Ulf Teichgräber
PURPOSE: To evaluate clinical outcomes and possible MR imaging predictors of clinical success after prostatic artery embolization (PAE) with 250-μm hydrogel particles. MATERIALS AND METHODS: During a span of 1.5 years, 30 patients with moderate to severe lower urinary tract symptoms were included in a prospective, nonrandomized study. Embolization of at least one prostatic artery was considered as technical success. International Prostate Symptom Score (IPSS), quality of life (QOL), peak urinary flow rate (Qmax ), residual urine volume, prostate volume, prostate-specific antigen level, and International Index of Erectile Function (IIEF) were recorded at baseline and at 1, 3, and 6 months after PAE...
June 14, 2018: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/29909472/the-impact-of-5%C3%AE-reductase-inhibitor-use-for-male-pattern-hair-loss-on-men-s-health
#12
REVIEW
Mohammed A Said, Akanksha Mehta
PURPOSE OF REVIEW: Male pattern hair loss, mediated by dihydrotestosterone, is a common hair loss disorder, affecting over 50% of men over the age of 50. The 5-α reductase inhibitors, finasteride and dutasteride, are Food and Drug Administration-approved drugs for the treatment of this disorder. Several recent studies have reported adverse sexual and spermatogenic events among young men using 5-α reductase inhibitors, such as erectile dysfunction, decreased ejaculate volume, decreased libido, and infertility...
June 16, 2018: Current Urology Reports
https://www.readbyqxmd.com/read/29909432/pharmacokinetics-of-a-novel-sildenafil-orodispersible-film-administered-by-the-supralingual-and-the-sublingual-route-to-healthy-men
#13
Luca Loprete, Chiara Leuratti, Valeria Frangione, Milko Radicioni
BACKGROUND: Sildenafil was the first selective drug available on the market as oral therapy for erectile dysfunction (ED). A novel sildenafil orodispersible film (ODF) for ED treatment, containing sildenafil citrate, has recently been marketed. OBJECTIVES: Study objective was to investigate sildenafil bioavailability of the novel ODF formulation after sublingual and supralingual administration. METHODS: In this randomised, two-way cross-over study, 12 healthy male volunteers received a single 50 mg sildenafil dose by the sublingual and supralingual administration routes...
June 16, 2018: Clinical Drug Investigation
https://www.readbyqxmd.com/read/29908868/robotic-assisted-urethra-sparing-simple-prostatectomy-via-an-extraperitoneal-approach
#14
Ping Wang, Dan Xia, SunYi Ye, DeBo Kong, Jie Qin, TaiLe Jing, YeQing Mao, HongZhou Meng, Shuo Wang
OBJECTIVE: To present a original technique of robotic-assisted urethra-sparing simple prostatectomy (RAUSP) for treating patients with benign prostatic hyperplasia (BPH). MATERIALS AND METHODS: From Apr 2015 to Dec 2016, 27 patients underwent RAUSP via an extraperitoneal approach. Baseline patient characteristics, perioperative outcomes, pathological outcomes, postoperative clavien complications, International Prostate Symptom Score, International Index of Erectile Function and ejaculatory function were assessed...
June 14, 2018: Urology
https://www.readbyqxmd.com/read/29908867/plaque-calcification-an-important-predictor-of-collagenase-clostridium-histolyticum-treatment-outcomes-for-men-with-peyronie-s-disease
#15
Kevin Wymer, Matthew Ziegelmann, Joshua Savage, Tobias Kohler, Landon Trost
OBJECTIVE: To compare outcomes of men with or without calcified plaques undergoing collagenase clostridium histolyticum (CCH) injections for Peyronie's Disease (PD) and identify predictors of CCH success. MATERIAL AND METHODS: From March 2014 through January 2017, data were prospectively collected on 192 patients who underwent 1-4 cycles of CCH for the treatment of PD. Of these, 115 completed ≥2 CCH cycles and had data on curvature assessment. The primary outcome was the percentage of men with >20% improvement in composite curvature...
June 14, 2018: Urology
https://www.readbyqxmd.com/read/29908630/penile-prostheses
#16
REVIEW
Ervin Kocjancic, Valerio Iacovelli
Phalloplasty represents the most complete genitoperineal transformation for trans men. Although voiding while standing is a priority for most trans men, most patients want to use the neophallus for sexual experience after they are accustomed to their new voiding abilities. Different techniques have been used to obtain rigidity in the neophallus, often resulting in complications and failure. Implantation of an erectile prosthesis remains the best option for achieving sexual intercourse in trans men. This article discusses the current state of art of penile prostheses in trans men, including a description of the prostheses, techniques for implantation, and complications...
July 2018: Clinics in Plastic Surgery
https://www.readbyqxmd.com/read/29908227/hypogastric-preservation-using-retrograde-endovascular-bypass
#17
Mathew Wooster, Paul Armstrong, Martin Back
OBJECTIVE: Maintenance of pelvic circulation has been connected to reduced risks of ischemic colitis, buttock claudication, erectile dysfunction, and spinal cord ischemia during the treatment of extensive aorto-iliac aneurysmal disease. We evaluate the mid to late follow up of a cohort of patients treated using one preservation technique, the endovascular external (EIA) to internal (IIA) iliac artery bypass. METHODS: All patients undergoing elective retrograde EIA-IIA endovascular bypass at a single institution were retrospectively reviewed over a ten-year period from 2006-2016...
June 13, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29902838/icariside-ii-promotes-the-differentiation-of-adipose-tissue-derived-stem-cells-to-schwann-cells-to-preserve-erectile-function-after-cavernous-nerve-injury
#18
Tao Zheng, Tian-Biao Zhang, Chao-Liang Wang, Wei-Xing Zhang, Dong-Hui Jia, Fan Yang, Yang-Yang Sun, Xiao-Ju Ding, Rui Wang
Icariside II (ICA II) is used in erectile dysfunction treatment. Adipose tissue-derived stem cells (ADSCs) are efficient at improving erectile function. This study aimed to explore the action mechanism of ADSCs in improving erectile function. ADSCs were isolated from the adipose tissues of rats. Cell proliferation was determined using the Cell Counting Kit-8 (CCK-8) assay. The expressions of mRNA and protein were determined separately through qRT-PCR and western blot. The endogenous expressions of related genes were regulated using recombinant plasmids and cell transfection...
June 14, 2018: Molecules and Cells
https://www.readbyqxmd.com/read/29901310/-current-role-of-sildenafil-in-the-management-of-erectile-dysfunction
#19
N D Akhvlediani, I P Matyukhov
Sildenafil is the first phosphodiesterase type 5 inhibitor (PDE-5), used in the management of erectile dysfunction (ED). The effectiveness and safety of the original drug have been studied most extensively among ED medications. Sildenafil has been successfully used for ED of different etiology and severity. To date, this PDE-5 remains the drug of choice for many patients with erectile dysfunction.
May 2018: Urologii︠a︡
https://www.readbyqxmd.com/read/29901304/-the-role-of-tadalafil-in-the-management-of-sexual-dysfunctions
#20
E A Efremov, E V Kasatonova, Ya I Mel'nik, A A Nikushina
Erectile dysfunction (ED) has a significant negative impact on the quality of life of the patients and their partners. The sequence and regimens of ED therapy have become quite evident since the advent of phosphodiesterase type 5 inhibitors (PDE-5). However, there have been continued basic research of the efficacy and safety of these agents and studies aimed at new therapeutic goals. In recent years, the attention of researchers has shifted into a wider range of issues related to the personalized PDE-5 therapy, including sexual satisfaction, psychosocial variables (e...
May 2018: Urologii︠a︡
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