keyword
https://read.qxmd.com/read/38532769/arthroscopic-saucerization-of-discoid-lateral-meniscus-with-meniscus-repair-as-indicated-results-in-excellent-outcomes-in-pediatric-patients-younger-than-12-years-of-age
#21
JOURNAL ARTICLE
George A Rublev, Levan Natchkebia, Vazha Gaprindashvili, Mohamed Ahmed Mohamed, Tamaz Tamazishvili, Irakli Kartozia, Mikheil Zimlitski
PURPOSE: To evaluate the experiences and outcomes of arthroscopic partial meniscectomy in symptomatic non-Wrisberg discoid lateral meniscus in children younger than 12 years old at a single center. METHODS: We retrospectively reviewed the medical records of all pediatric patients who were treated for non-Wrisberg discoid meniscus at our institute between 2013 and 2021. Patients were separated into 2 groups: Patients who underwent partial resection with saucerization (group A) or patients who underwent saucerization, tear repair, and fixation (group B)...
April 2024: Arthroscopy, sports medicine, and rehabilitation
https://read.qxmd.com/read/38532447/peptidoglycan-in-osteoarthritis-synovial-tissue-is-associated-with-joint-inflammation
#22
JOURNAL ARTICLE
Meaghan N Holub, Amanda Wahhab, Joseph R Rouse, Rebecca Danner, Lauren G Hackner, Christine B Duris, Mecaila E McClune, Jules M Dressler, Klemen Strle, Brandon L Jutras, Adam I Edelstein, Robert B Lochhead
OBJECTIVES: Peptidoglycan (PG) is an arthritogenic bacterial cell wall component whose role in human osteoarthritis is poorly understood. The purpose of this study was to determine if PG is present in synovial tissue of osteoarthritis patients at the time of primary total knee arthroplasty (TKA), and if its presence is associated with inflammation and patient reported outcomes. METHODS: Intraoperative synovial tissue and synovial fluid samples were obtained from 56 patients undergoing primary TKA, none of whom had history of infection...
March 27, 2024: Arthritis Research & Therapy
https://read.qxmd.com/read/38532422/cost-effectiveness-and-cost-utility-of-the-ball-and-socket-trapeziometacarpal-prosthesis-compared-to-trapeziectomy-and-ligament-reconstruction-study-protocol-for-a-randomized-controlled-clinical-trial
#23
JOURNAL ARTICLE
Serafín Lirola-Palmero, Guillem Salva-Coll, Aina María Yáñez-Juan, Eduardo Sánchez-Iriso
BACKGROUND: Trapeziometacarpal (TMC) osteoarthritis (OA) is a common cause of pain and weakness during thumb pinch leading to disability. There is no consensus about the best surgical treatment in unresponsive cases. The treatment is associated with costs and the recovery may take up to 1 year after surgery depending on the procedure. No randomized controlled trials have been conducted comparing ball and socket TMC prosthesis to trapeziectomy with ligament reconstruction. METHODS: A randomized, blinded, parallel-group superiority clinical trial comparing trapeziectomy with abductor pollicis longus (APL) arthroplasty and prosthetic replacement with Maïa® prosthesis...
March 27, 2024: Trials
https://read.qxmd.com/read/38532343/phenome-wide-causal-associations-between-osteoarthritis-and-other-complex-traits-through-the-latent-causal-variable-analysis
#24
JOURNAL ARTICLE
Lin Mei, Zhiming Zhang, Ruiqi Chen, Zhihong Li
BACKGROUND: Individuals with osteoarthritis present with comorbidities, and the potential causal associations remain incompletely elucidated. The present study undertook a large-scale investigation about the causality between osteoarthritis and variable traits, using the summary-level data of genome-wide association studies (GWAS). METHODS: The present study included the summary-level GWS data of knee osteoarthritis, hip osteoarthritis, hip or knee osteoarthritis, hand osteoarthritis, and other 1355 traits...
March 26, 2024: BMC Musculoskeletal Disorders
https://read.qxmd.com/read/38531745/long-term-effects-of-exercise-therapy-versus-arthroscopic-partial-meniscectomy-for-degenerative-meniscal-tear-a-meta-analysis-of-randomized-controlled-trials
#25
JOURNAL ARTICLE
Jiahao Meng, Hang Tang, Yifan Xiao, Weijie Liu, Yumei Wu, Yilin Xiong, Shuguang Gao
BACKGROUND: Degenerative meniscal tear (DMT) is common in the elderly population. However, there has been controversy over the treatment of DMT regarding whether to adopt arthroscopic partial meniscectomy (APM) or exercise therapy (ET). In order to compare the long-term outcomes between the two treatment methods, we conducted a meta-analysis of randomized controlled trials (RCTs) with long-term follow-up. METHODS: PubMed, Cochrane Library, Embase, and Web of Science were last searched on 16 April 2023 for studies on DMT that compared the clinical outcomes between APM and ET...
March 25, 2024: Asian Journal of Surgery
https://read.qxmd.com/read/38531574/association-between-osteoarthritis-and-cardiovascular-disease-in-elderly-in-japan-an-administrative-claims-database-analysis
#26
JOURNAL ARTICLE
Takuya Uematsu, Shuko Nojiri, Muneaki Ishijima, Yuji Nishizaki
OBJECTIVE: To investigate whether osteoarthritis (OA) is a risk factor for cardiovascular disease (CVD); whether there are differences concerning ischaemic heart disease (IHD), congestive heart failure (CHF) and stroke; and whether there are differences between OA sites (hips, knees and hand) in predicting CVD onset. DESIGN: Population-based matched case-control study. SETTING: Health insurance claims data among Japanese patients. PARTICIPANTS: Japanese patients aged ≥65 years with newly diagnosed CVD and hospitalised between January 2015 and December 2020 (cases) and age-matched and sex-matched 1:1 individuals (controls)...
March 25, 2024: BMJ Open
https://read.qxmd.com/read/38531488/the-dysregulated-autophagy-in-osteoarthritis-revisiting-molecular-profile
#27
JOURNAL ARTICLE
Liang Liu, Jie Wang, Lu Liu, Wenling Shi, Huajie Gao, Lun Liu
The risk factors of osteoarthritis (OA) are different and obesity, lifestyle, inflammation, cell death mechanisms and diabetes mellitus are among them. The changes in the biological mechanisms are considered as main regulators of OA pathogenesis. The dysregulation of autophagy is observed in different human diseases. During the pathogenesis of OA, the autophagy levels (induction or inhibition) change. The supportive and pro-survival function of autophagy can retard the progression of OA. The protective autophagy prevents the cartilage degeneration...
March 24, 2024: Progress in Biophysics and Molecular Biology
https://read.qxmd.com/read/38531464/do-we-understand-sex-related-differences-governing-dimorphic-disease-mechanisms-in-preclinical-animal-models-of-osteoarthritis
#28
JOURNAL ARTICLE
Mona Dvir-Ginzberg, Yonathan H Maatuf, Ali Mobasheri
Research conducted using murine preclinical models of osteoarthritis (OA) over the last three decades has brought forth many exciting developments showcasing mechanisms and pathways that ‎drive disease pathogenesis. These models have identified therapeutic targets that can be modulated via innovative biologicals and pharmaceuticals. However, many of these ‎approaches have failed to translate to humans and reach the clinic. This commentary aims to highlight some of the key ‎hurdles in the translation of novel findings using preclinical OA models...
March 24, 2024: Osteoarthritis and Cartilage
https://read.qxmd.com/read/38530683/efficacy-of-intra-articular-corticosteroid-injection-for-nonsurgical-management-of-trapeziometacarpal-osteoarthritis-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#29
JOURNAL ARTICLE
Alexandra N Krez, Kevin A Wu, Kevin M Klifto, Tyler S Pidgeon, Christopher S Klifto, David S Ruch
PURPOSE: As osteoarthritis (OA) of the trapeziometacarpal (TMC) joint leads to a high degree of disease burden with compromises in rudimentary and fine movements of the hand, intra-articular injections may be a desirable treatment option. However, because there are no evidence-based guidelines, the choice of intra-articular injection type is left to the discretion of the individual surgeon in collaboration with the patient. The purpose of our study was to perform a systematic review and meta-analysis using level I studies to compare outcomes following corticosteroid and alternative methods of intra-articular injections for the management of TMC OA...
March 26, 2024: Journal of Hand Surgery
https://read.qxmd.com/read/38530504/nonmetallic-tension-band-fixation-is-a-viable-and-low-complication-surgical-technique-in-patellar-fractures-a-five-year-retrospective-study
#30
JOURNAL ARTICLE
Rovere Giuseppe, Romeo Michele, Farinelli Luca, Giancani Michele, Gangi Giuseppe, Manuri Valentina, Fortunato Giustra, Francesco Bosco, Lawrence Camarda
BACKGROUND: Traditionally, patellar fractures (PFs) have been managed using metallic tension band fixation, a method often associated with a notable rate of complications. Considering these challenges, this study explores the potential of nonmetallic fixation as a treatment option for PFs. This research aims to provide robust evidence supporting the use of the nonmetallic tension band fixation technique as an effective alternative to conventional metallic tension band fixation, thereby advancing the standard of care in treating these fractures...
March 26, 2024: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://read.qxmd.com/read/38530304/independent-and-combined-effects-of-obesity-and-traumatic-joint-injury-to-the-structure-and-composition-of-rat-knee-cartilage
#31
JOURNAL ARTICLE
Kalle Karjalainen, Petri Tanska, Kelsey H Collins, Walter Herzog, Rami K Korhonen, Eng Kuan Moo
Osteoarthritis (OA) is a multifactorial joint disease characterized by articular cartilage degradation. Risk factors for OA include joint trauma, obesity, and inflammation, each of which can affect joint health independently, but their interaction and the associated consequences of such interaction were largely unexplored. Here, we studied compositional and structural alterations in knee joint cartilages of Sprague-Dawley rats exposed to two OA risk factors: joint injury and diet-induced obesity. Joint injury was imposed by surgical transection of anterior cruciate ligaments (ACLx), and obesity was induced by a high fat/high sucrose diet...
March 26, 2024: Connective Tissue Research
https://read.qxmd.com/read/38530232/patient-preferences-and-their-effects-on-rehabilitation-outcomes-a-secondary-analysis-of-a-randomized-controlled-trial
#32
JOURNAL ARTICLE
Nikolaj Agger, Jim Nørgaard Bøjstrup, David Høyrup Christiansen
OBJECTIVE: To assess the effect of aligning patients' preferences with specific rehabilitation delivery modes on rehabilitation outcomes. DESIGN: A secondary analysis of a randomized controlled trial (RCT). METHODS: The study cohort comprised 208 patients referred for physiotherapy rehabilitation after non-surgical or surgical interventions for rotator cuff injury, shoulder impingement, or acromioclavicular osteoarthritis. Participants were randomly assigned to one of three rehabilitation modalities: 1) group-based exercise, 2) individual exercise, or 3) home exercise...
March 26, 2024: Journal of Orthopaedic and Sports Physical Therapy
https://read.qxmd.com/read/38530147/how-do-small-quantities-of-cartilage-sodium-channels-play-a-significant-role-in-osteoarthritis
#33
JOURNAL ARTICLE
Xiaohong Kong, Chuan-Ju Liu
No abstract text is available yet for this article.
March 2024: Clinical and Translational Medicine
https://read.qxmd.com/read/38529902/a-comparison-of-cemented-femoral-fixation-via-anterior-versus-posterior-approach-total-hip-arthroplasty-an-analysis-of-60-739-total-hip-arthroplasties
#34
JOURNAL ARTICLE
Wayne Hoskins, Sophie Corfield, Yi Peng, Stephen E Graves, Roger Bingham
BACKGROUND: Anterior approach total hip arthroplasty (THA) decreases the rate of dislocation but increases femoral-sided complications in the way of periprosthetic fractures and component loosening. A cemented prosthesis may reduce femoral-sided complications and improve the risk:benefit profile of anterior approach THA. METHODS: Data from the Australian National Joint Replacement Registry were analysed for patients undergoing primary THA via the anterior or posterior approach using a cemented polished femoral stem from January 2015 to December 2021...
March 26, 2024: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
https://read.qxmd.com/read/38529883/long-term-follow-up-of-total-hip-arthroplasty-using-polyethylene-ceramic-composite-sandwich-liner
#35
JOURNAL ARTICLE
Daniel Rodríguez-Pérez, Thiago Carnaval, Marcos-Del-Carmen Rodríguez, Antonio Coscujuela-Maña, José-Luis Agulló, Sebastián Videla
INTRODUCTION: Ceramic-on-ceramic bearings have been widely used since their introduction in the 1970s. First-generation ceramics have very high fracture (breakage) rates. To overcome this, in the 1990s, modular cotyloid insert designs were developed, consisting of a ceramic and polyethylene composite (sandwich-type) liner; however, high implant fracture rates were observed in the medium term. We aimed to estimate the cumulative incidences of revision surgery (implant failure) and implant failure due to fractures, survival rates (time-to-revision surgery and time-to-fracture), and the long-term clinical and radiological outcomes in our series...
March 26, 2024: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
https://read.qxmd.com/read/38529694/unicompartmental-knee-arthroplasty-improves-mental-health-in-patients-with-single-compartment-knee-osteoarthritis
#36
JOURNAL ARTICLE
Kevin D Plancher, Karen K Briggs, Sarah Commaroto, Kathryn Dotterweich, Karina Wang, Stephanie C Petterson
PURPOSE: The purpose of this study was to determine if preoperative mental health status improves following unicompartmental knee arthroplasty (UKA) in patients with single compartment knee osteoarthritis (OA). METHODS: A total of 163 patients underwent UKA [115 (71%) medial, 48 (29%) lateral] (mean age = 65 ± 11) completed preoperative and minimum 2-year postoperative veterans RAND 12 item health survey (VR-12) mental component score (MCS)...
March 26, 2024: Knee Surgery, Sports Traumatology, Arthroscopy
https://read.qxmd.com/read/38529690/almost-79-survival-rate-at-10-year-follow-up-for-the-patellofemoral-joint-arthroplasty-an-italian-prosthetic-registry-study
#37
JOURNAL ARTICLE
Anna Pagano, Piero Agostinone, Domenico Alesi, Dalila Caputo, Maria Pia Neri, Alberto Grassi, Stefano Zaffagnini
PURPOSE: The aims of the present study were (1) to evaluate the survival of patellofemoral joint (PFJ) arthroplasty in a large cohort of patients using data obtained from an Italian regional arthroplasty registry and (2) to collect clinical outcomes of a subgroup of patients, with a minimum follow-up of 4 years. The hypotheses were that PFJ arthroplasty is a procedure that had good survival and clinical outcomes, not inferior to those reported in the literature for primary total knee arthroplasty (TKA)...
March 26, 2024: Knee Surgery, Sports Traumatology, Arthroscopy
https://read.qxmd.com/read/38529576/life-expectancy-of-patients-undergoing-total-knee-arthroplasty-comparison-with-general-population
#38
JOURNAL ARTICLE
Sanghyo Kim, Samuel Jaeyoon Won, Na-Kyoung Lee, Chong Bum Chang
BACKGROUND: This study aimed to analyze the life expectancy and cause of death in osteoarthritis (OA) patients who underwent total knee arthroplasty (TKA) and to identify risk factors that affect long-term mortality rate after TKA. METHODS: Among 601 patients, who underwent primary TKA due to OA by a single surgeon from July 2005 to December 2011, we identified patients who died after the operation using data obtained from the National Statistical Office of Korea...
March 25, 2024: Journal of Korean Medical Science
https://read.qxmd.com/read/38529294/inflammatory-synovial-biomarkers-and-state-of-the-tibiofemoral-joint-in-the-post-surgical-settings-a-narrative-review
#39
REVIEW
Luke V Tollefson, Mitchell I Kennedy, Adam J Tagliero, Konrad Malinowski, Jorge Chahla, Gilbert Moatshe, Nicholas I Kennedy, Robert F LaPrade, Nicholas N DePhillipo
BACKGROUND AND OBJECTIVE: Knee surgery attempts to restore the native biomechanics of the knee, improve stability, and decrease the progression of osteoarthritis (OA). However, despite improvements in surgical techniques, tissue degradation and OA are common after knee surgery, occurring in higher rates in surgical knees compared to non-surgical knees. The aim of this study is to analyze previous literature to determine which synovial fluid biomarkers contribute to knee tissue degradation and decrease patient outcomes in the post-surgical setting of the knee...
2024: Annals of joint
https://read.qxmd.com/read/38529278/metabolic-profiling-of-synovial-fluid-in-human-temporomandibular-joint-osteoarthritis
#40
JOURNAL ARTICLE
Dahe Zhang, Yuxin Zhang, Simo Xia, Pei Shen, Chi Yang
INTRODUCTION: Temporomandibular joint (TMJ) osteoarthritis (OA) is a common TMJ degenerative disease with an unclear mechanism. Synovial fluid (SF), an important component of TMJ, contains various proteins and metabolites that may directly contribute to OA. The present study aimed to investigate the influence of SF in TMJOA at the metabolite level. METHODS: Untargeted and widely targeted metabolic profiling were employed to identify metabolic changes in SF of 90 patients with different TMJOA grades according to TMJ magnetic resonance imaging...
2024: Frontiers in Immunology
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