keyword
MENU ▼
Read by QxMD icon Read
search

Meta-analysis

keyword
https://www.readbyqxmd.com/read/29150886/ruxolitinib-associated-infections-a-systematic-review-and-meta-analysis
#1
Federico Lussana, Marco Cattaneo, Alessandro Rambaldi, Alessandro Squizzato
Ruxolitinib exerts immunosuppressive activity that may increase the risk of infectious complications. We performed a systematic review of the literature with the aim of estimating the risk of infections in patients treated with ruxolitinib. Studies were identified by electronic search of MEDLINE and EMBASE database. Differences in the incidence of infectious events between ruxolitinib and comparison groups were expressed as odds ratios (ORs) and 95% confidence intervals (95% CI). Five phase III randomized clinical trials (RCTs) (3 phase IIIa with their extended phase and 2 phase IIIb), 6 phase IV studies and 28 case reports were included in this systematic review...
November 18, 2017: American Journal of Hematology
https://www.readbyqxmd.com/read/29150713/efficacy-of-silexan-in-subthreshold-anxiety-meta-analysis-of-randomised-placebo-controlled-trials
#2
Hans-Jürgen Möller, Hans-Peter Volz, Angelika Dienel, Sandra Schläfke, Siegfried Kasper
Subthreshold psychiatric disorders do not fully meet the diagnostic criteria of syndromal disorders but may be associated with comparable disability. To investigate the anxiolytic effect of Silexan, an active substance from lavender oil for oral administration, in patients with subthreshold anxiety, a meta-analysis that included all published trials with Silexan in this indication was performed. Three randomised, placebo-controlled trials in subthreshold anxiety disorders (anxiety disorder not otherwise specified, restlessness and agitation, mixed anxiety and depressive disorder) were included...
November 17, 2017: European Archives of Psychiatry and Clinical Neuroscience
https://www.readbyqxmd.com/read/29150631/effect-of-long-term-incretin-based-therapies-on-ischemic-heart-diseases-in-patients-with-type-2-diabetes-mellitus-a-network-meta-analysis
#3
Che-Yi Chou, Ying-Tzu Chang, Jia-Lian Yang, Jiun-Yi Wang, Tsui-Er Lee, Ruey-Yun Wang, Chin-Chuan Hung
Patients with type 2 diabetes mellitus (T2DM) experience many cardiovascular complications. Several studies have demonstrated the cardioprotective effects of incretin-based therapies; however, there are few studies on the effects of long-term incretin-based therapies on cardiovascular events. Therefore, the present study conducted a systematic review and network meta-analysis to evaluate the effects of long-term incretin-based therapies on ischaemic diseases. We searched PubMed, CENTRAL, and Clinicaltrial.gov to retrieve randomised control trials reported until December 2016 and enrolled only RCTs with more than a 1-year follow-up...
November 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29150479/impact-of-variation-in-functions-and-delivery-on-the-effectiveness-of-behavioural-and-mood-management-interventions-for-smoking-cessation-in-people-with-depression-protocol-for-a-systematic-review-and-meta-analysis
#4
Gemma Taylor, Paul Aveyard, Regina Van der Meer, Daniel Toze, Bobby Stuijfzand, David Kessler, Marcus Munafò
INTRODUCTION: Tobacco is the world's leading preventable cause of disease and death. People with depression are twice as likely to smoke and are less responsive to standard tobacco treatments as compared with the general population. A Cochrane systematic review of randomised controlled trials of smoking cessation treatment for smokers with current or historical depression found that adding mood management to usual smoking treatment improved quit rates. However, the review did not examine if variation in intervention delivery or intervention functions impacted on treatment effectiveness...
November 16, 2017: BMJ Open
https://www.readbyqxmd.com/read/29150464/testosterone-therapy-in-hypogonadal-men-a-systematic-review-and-network-meta-analysis
#5
Jesse Elliott, Shannon E Kelly, Adam C Millar, Joan Peterson, Li Chen, Amy Johnston, Ahmed Kotb, Becky Skidmore, Zemin Bai, Muhammad Mamdani, George A Wells
OBJECTIVE: To assess the relative effects of individual testosterone products among hypogonadal men. DESIGN: Systematic review and network meta-analysis. METHODS: We searched MEDLINE, Embase, Cochrane CENTRAL, and grey literature (25 May 2017) for randomised-controlled trials (RCTs) and non-randomised studies (NRS) that involved hypogonadal men given testosterone replacement therapy (TRT) for ≥3 months. Comparators were placebo, another TRT, or the same product at a different dose...
November 16, 2017: BMJ Open
https://www.readbyqxmd.com/read/29150458/diagnostic-accuracy-of-neonatal-assessment-for-gestational-age-determination-a-systematic-review
#6
REVIEW
Anne Cc Lee, Pratik Panchal, Lian Folger, Hilary Whelan, Rachel Whelan, Bernard Rosner, Hannah Blencowe, Joy E Lawn
CONTEXT: An estimated 15 million neonates are born preterm annually. However, in low- and middle-income countries, the dating of pregnancy is frequently unreliable or unknown. OBJECTIVE: To conduct a systematic literature review and meta-analysis to determine the diagnostic accuracy of neonatal assessments to estimate gestational age (GA). DATA SOURCES: PubMed, Embase, Cochrane, Web of Science, POPLINE, and World Health Organization library databases...
November 17, 2017: Pediatrics
https://www.readbyqxmd.com/read/29150418/immune-enhancing-formulas-for-patients-with-cancer-undergoing-esophagectomy-systematic-review-protocol
#7
Astrid Naranjo, Elizabeth Isenring, Laisa Teleni
BACKGROUND: Adult patients with an esophageal cancer can potentially be compromised with postoperative leaks or fistulae if patients' nutritional status is in a vulnerable stage. Currently in Australia, there is a growing need for clinicians to know whether use of immune-enhancing formulas (IEFs) containing Arg, omega-3, and RNA are a cost-effective approach compared with isonitrogenous-isocaloric formulas to reduce postoperative infectious complications in esophagectomy patients. Since IEFs may carry higher costs, this has led to inconsistencies in practice among clinicians and hospitals...
November 17, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/29150233/management-of-first-depression-or-generalized-anxiety-disorder-episode-in-adults-in-primary-care-a-systematic-metareview
#8
Damien Driot, Michel Bismuth, Adrien Maurel, Julie Soulie-Albouy, Jordan Birebent, Stéphane Oustric, Julie Dupouy
CONTEXT: General Practitioners (GPs) are the leading antidepressants prescribers in Europe and in France. Difficulties in implementing existing recommendations in daily practice have been described. OBJECTIVE: The objective of this study was to elaborate two algorithms to guide GPs in the patient management for a first major depressive disorder (MDD) or generalized anxiety disorder (GAD) episode in primary care. DATA SOURCES: PubMed, Cochrane, and ISI Web of Science were explored using mainly the following keywords: depressive disorder, anxiety disorders, antidepressive agents or antidepressant...
November 14, 2017: La Presse Médicale
https://www.readbyqxmd.com/read/29150169/vitamin-d-and-walking-speed-in-older-adults-systematic-review-and-meta-analysis
#9
REVIEW
Cedric Annweiler, Samir Henni, Stéphane Walrand, Manuel Montero-Odasso, Gustavo Duque, Guillaume T Duval
Vitamin D is involved in musculoskeletal health. There is no consensus on a possible association between circulating 25-hydroxyvitamin D (25OHD) concentrations and walking speed, a 'vital sign' in older adults. Our objective was to systematically review and quantitatively assess the association of 25OHD concentration with walking speed. A Medline search was conducted on June 2017, with no limit of date, using the MeSH terms "Vitamin D" OR "Vitamin D Deficiency" combined with "Gait" OR "Gait disorders, Neurologic" OR "Walking speed" OR "Gait velocity"...
December 2017: Maturitas
https://www.readbyqxmd.com/read/29150165/effects-of-programmed-exercise-on-depressive-symptoms-in-midlife-and-older-women-a-meta-analysis-of-randomized-controlled-trials
#10
REVIEW
Faustino R Pérez-López, Samuel J Martínez-Domínguez, Héctor Lajusticia, Peter Chedraui
OBJECTIVE: To perform a systematic review and meta-analysis to clarify the effect of programmed exercise on depressive symptoms (DSs) in midlife and older women. METHODS: We carried out a structured search of PubMed-Medline, Web of Science, Scopus, Embase, Cochrane Library and Scielo, from database inception through June 29, 2017, without language restriction. The search included the following terms: "depression", "depressive symptoms", "exercise", "physical activity", "menopause", and "randomized controlled trial" (RCTs) in midlife and older women...
December 2017: Maturitas
https://www.readbyqxmd.com/read/29150156/the-efficacy-of-danshen-injection-as-adjunctive-therapy-in-treating-angina-pectoris-a-systematic-review-and-meta-analysis
#11
REVIEW
Huikai Shao, Mengsi Li, Fuchao Chen, Lianghua Chen, Zhengjin Jiang, Lingguo Zhao
BACKGROUND: During the last 40 years, Danshen injection has been widely used as an adjunctive therapy for angina pectoris in China, but its efficacy is not yet well defined. The objective of this study was to verify the efficacy of Danshen injection as adjunctive therapy in treating angina pectoris. METHODS: The major databases including PubMed, Cochrane Library, Sino-Med, Medline, Embase, Google Scholar, China National Knowledge Infrastructure, Wanfang Databases, Chinese Scientific Journal Database, Chinese Biomedical Literature Database and the Chinese Science Citation Database were systematically searched for the published randomised controlled trials (RCTs) on Danshen injection until April 2016...
November 6, 2017: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/29150071/efficacy-of-bleach-baths-in-reducing-severity-of-atopic-dermatitis-a-systematic-review-and-meta-analysis
#12
Rishi Chopra, Paras P Vakharia, Ryan Sacotte, Jonathan I Silverberg
BACKGROUND: Bleach baths have been proposed as a treatment for decreasing the severity of atopic dermatitis (AD). However, conflicting results have been found regarding their efficacy. OBJECTIVE: To determine the efficacy of bleach vs water baths at decreasing AD severity. METHODS: We performed a systematic review of all studies evaluating the efficacy of bleach baths for AD. Cochrane, EMBASE, GREAT, LILACS, MEDLINE, and Scopus were searched...
November 2017: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/29149887/prostate-cancer-in-firefighting-and-police-work-a-systematic-review-and-meta-analysis-of-epidemiologic-studies
#13
REVIEW
Jeavana Sritharan, Manisha Pahwa, Paul A Demers, Shelley A Harris, Donald C Cole, Marie-Elise Parent
OBJECTIVES: We conducted a systematic review and meta-analysis to evaluate potential associations between firefighting and police occupations, and prostate cancer incidence and mortality. METHODS: Original epidemiological studies published from 1980 to 2017 were identified through PubMed and Web of Science. Studies were included if they contained specific job titles for ever/never firefighting and police work and associated prostate cancer risk estimates with 95% confidence intervals (CI)...
November 17, 2017: Environmental Health: a Global Access Science Source
https://www.readbyqxmd.com/read/29149868/can-high-flow-nasal-cannula-reduce-the-rate-of-reintubation-in-adult-patients-after-extubation-a-meta-analysis
#14
Yue-Nan Ni, Jian Luo, He Yu, Dan Liu, Bin-Miao Liang, Rong Yao, Zong-An Liang
BACKGROUND: The effects of high flow nasal cannula (HFNC) on adult patients after extubation remain controversial. We aimed to further determine the effectiveness of HFNC in comparison to noninvasive positive pressure ventilation (NIPPV) and conventional oxygen therapy (COT). METHODS: The Pubmed, Embase, Medline, Cochrane Central Register of Controlled Trails (CENTRAL) as well as the Information Sciences Institute (ISI) Web of Science were searched for all the controlled study comparing HFNC with NIPPV and COT in adult patients after extubation...
November 17, 2017: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/29149828/vortioxetine-treatment-for-anxiety-disorder-a-meta-analysis-study
#15
Anne Yee, Chong Guan Ng, Loh Huai Seng
BACKGROUND: Vortioxetine is a multimodal antidepressant that has been developed for the treatment of major depressive and anxiety disorders. The aim of this review is to quantitatively synthesize all data of the efficacy, safety and tolerability of Vortioxetine in treating anxiety disorder. METHOD: Terms of "Vortioxetine" OR "LuAA21004" AND "anxiety" OR "fear" OR "panic" OR "phobia" were searched. A total of two phase II and five phase III clinical trials were found...
November 17, 2017: Current Drug Targets
https://www.readbyqxmd.com/read/29149804/systematic-literature-review-and-network-meta-analysis-of-cladribine-tablets-versus-alternative-disease-modifying-treatments-for-relapsing-remitting-multiple-sclerosis
#16
M K Siddiqui, I S Khurana, S Budhia, R Hettle, G Harty, S L Wong
OBJECTIVE: To assess the comparative efficacy and safety of cladribine tablets versus alternative disease modifying treatments (DMTs) in patients with active relapsing-remitting multiple sclerosis (RRMS), and in a subgroup with high disease activity (HRA+DAT), using systematic literature review (SLR) and network meta-analysis (NMA). METHODS: MEDLINE, Embase, MEDLINE In-Process and CENTRAL databases were systematically searched to identify English-language publications of relevant studies of approved DMTs for RRMS...
November 17, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/29149758/oligotrophy-as-a-major-driver-of-mercury-bioaccumulation-in-medium-to-high-trophic-level-consumers-a-marine-ecosystem-comparative-study
#17
Tiphaine Chouvelon, Pierre Cresson, Marc Bouchoucha, Christophe Brach-Papa, Paco Bustamante, Sylvette Crochet, Françoise Marco-Miralles, Bastien Thomas, Joël Knoery
Mercury (Hg) is a global contaminant of environmental concern. Numerous factors influencing its bioaccumulation in marine organisms have already been described at both individual and species levels (e.g., size or age, habitat, trophic level). However, few studies have compared the trophic characteristics of ecosystems to explain underlying mechanisms of differences in Hg bioaccumulation and biomagnification among food webs and systems. The present study aimed at investigating the potential primary role of the trophic status of systems on Hg bioaccumulation and biomagnification in temperate marine food webs, as shown by their medium-to high-trophic level consumers...
November 14, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/29149680/modification-of-the-association-between-high-ambient-temperature-and-health-by-urban-microclimate-indicators-a-systematic-review-and-meta-analysis
#18
REVIEW
Leah H Schinasi, Tarik Benmarhnia, Anneclaire J De Roos
BACKGROUND: Landscape characteristics, including vegetation and impervious surfaces, influence urban microclimates and may lead to within-city differences in the adverse health effects of high ambient temperatures. OBJECTIVE: Our objective was to quantitatively summarize the epidemiologic literature that assessed microclimate indicators as effect measure modifiers (EMM) of the association between ambient temperature and mortality or morbidity. METHODS: We systematically identified papers and abstracted relative risk estimates for hot and cool microclimate indicator strata...
November 14, 2017: Environmental Research
https://www.readbyqxmd.com/read/29149621/the-risk-factors-related-to-bruxism-in-children-a-systematic-review-and-meta-analysis
#19
REVIEW
Huaqi Guo, Tongxia Wang, Xiaohong Niu, Hui Wang, Weihan Yang, Jie Qiu, Lan Yang
OBJECTIVE: This systematic review was performed to determine the risk factors related to bruxism in children. DESIGN: This systematic review was conducted with reporting in agreement to the PRISMA statement and according to guidelines from the Cochrane Handbook for Systematic Reviews of Interventions. We conducted a systematic search of seven online databases, with the last search updated on 1st October 2016. The seven databases were Pubmed, Embase, Cochrane Library database, Web of Science, CNKI, CBM, and WF...
November 11, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/29149524/a-systematic-review-and-meta-analysis-of-fetal-outcomes-following-the-administration-of-influenza-a-h1n1-vaccination-during-pregnancy
#20
REVIEW
Chuan Zhang, Xiaodong Wang, Dan Liu, Lingli Zhang, Xin Sun
BACKGROUND: Pregnant women were identified as a population of priority for vaccination during the H1N1 influenza pandemic breaking out in 2009. OBJECTIVES: To assess adverse fetal outcomes following the administration of H1N1 pandemic vaccination during pregnancy. SEARCH STRATEGY: PubMed, Embase, and Cochrane Library were searched up to January 2017. SELECTION CRITERIA: Cohort studies investigating fetal outcomes after H1N1 influenza vaccination during pregnancy were eligible...
November 17, 2017: International Journal of Gynaecology and Obstetrics
keyword
keyword
4034
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"