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Xiaodi Liu, Liqun Ye, Shanshan Liu, Yinping Li, Xiaoxu Ji
ZnO microspheres, ZnO microflowers and ZnO nanorods are successfully synthesized via a convenient solvothermal method in distilled water-ethanol mixed medium. The as-prepared ZnO micro/nanomaterials are characterized by XRD, SEM, TEM, HRTEM, XPS, BET, and UV-Vis. The morphologies and exposed facets of the ZnO micro/nanomaterials can be controlled by simply changing the volume ratio of distilled water to ethanol, and their formation mechanisms are also proposed. In addition, the photocatalytic activities of the ZnO samples are investigated towards the photoreduction of CO2 to CO...
December 6, 2016: Scientific Reports
Xiaoxue Zhang, Si Wang
No abstract text is available yet for this article.
November 29, 2016: Science China. Life Sciences
Jie Liu, Yuling Huang, Guojuan Chen, Xiaoxue Liu, Zhijun Wang, Yibin Cao, Haitao Li, Lu Song, Chunhui Li, Hualing Zhao, Shuohua Chen, Yiming Wang, Ruiying Zhang, Anxin Wang, Shouling Wu
The association between systolic blood pressure (SBP) and cognitive function is controversial in elderly adults. In addition, few studies focused on the cumulative effect of SBP. We aimed to investigate the association between cumulative SBP exposure and cognitive function among middle-aged and elderly adults.The analysis was based on the Asymptomatic Polyvascular Abnormalities Community (APAC) study. The primary predictor was the cumulative SBP calculated by consecutive SBP values measured through baseline (2006-2007) up to the fourth examination (2012-2013)...
November 2016: Medicine (Baltimore)
Shangping Wang, Xiaoxue Zhang, Yaling Zhang
Cipher-policy attribute-based encryption (CP-ABE) focus on the problem of access control, and keyword-based searchable encryption scheme focus on the problem of finding the files that the user interested in the cloud storage quickly. To design a searchable and attribute-based encryption scheme is a new challenge. In this paper, we propose an efficiently multi-user searchable attribute-based encryption scheme with attribute revocation and grant for cloud storage. In the new scheme the attribute revocation and grant processes of users are delegated to proxy server...
2016: PloS One
Ruijie Zhang, Yu Zhu, Xiaoqing Dong, Beibei Liu, Nana Zhang, Xiaoxue Wang, Lei Liu, Chong Xu, Shile Huang, Long Chen
Cadmium (Cd), an environmental and industrial pollutant, affects the nervous system and consequential neurodegenerative disorders. Recently we have shown that celastrol prevents Cd-induced neuronal cell death partially by suppressing Akt/mTOR pathway. However, the underlying mechanism remains to be elucidated. Here we show that celastrol attenuated Cd-elevated intracellular free calcium ([Ca(2+) ]i ) level and apoptosis in neuronal cells. Celastrol prevented Cd-induced neuronal apoptosis by inhibiting Akt-mediated mTOR pathway, as inhibition of Akt with Akt inhibitor X or ectopic expression of dominant negative Akt reinforced celastrol's prevention of Cd-induced phosphorylation of S6K1/4E-BP1 and cell apoptosis...
November 27, 2016: Journal of Cellular Physiology
Xiaoxu Ji, Tammy R Eger, James P Dickey
Seats and cushions can attenuate whole-body vibration (WBV) exposures and minimize health risks for heavy machine operators. We successfully developed neural network (NN) algorithms to identify the vibration attenuation properties for four different seating conditions (seat/cushion combinations), and implemented each of the NN models to predict the equivalent daily exposure A(8) values for various vehicles in the forestry and mining environments. We also evaluated the performance of the new prototype No-Jolt™ air-inflated cushion and the original cushion of each seat with jolt exposures...
March 2017: Applied Ergonomics
Juan Meng, Yanchun Li, Xiaoxu Yuan, Yuewu Lu
We aimed to investigate the effects of febuxostat on IR and the expression of high-sensitivity C-reactive protein (hs-CRP) in patients with primary gout. Forty-two cases of primary gout patients without uric acid-lowering therapy were included in this study. After a physical examination, 20 age- and sex-matched patients were included as normal controls. The levels of fasting insulin (INS), fasting blood glucose (FBG), and hs-CRP were determined. IR was assessed using the Homeostasis Model Assessment of Insulin Resistance (HOMA-IR)...
November 23, 2016: Rheumatology International
Xinchen Kang, Xiaoxue Ma, Jianling Zhang, Xueqing Xing, Guang Mo, Zhonghua Wu, Zhihong Li, Buxing Han
We discovered that large nanodomains were formed in liquid solutions near the phase boundary, and their size increased dramatically as the composition of solutions approached the phase boundary. Different mesoporous materials were synthesized using nanodomains as templates, and the pore size could be controlled simply by the composition of solutions.
December 6, 2016: Chemical Communications: Chem Comm
Fang Li, Xiaoxue Fan, Yu Zhang, Lizhi Pang, Xiaonan Ma, Meijia Song, Junping Kou, Boyang Yu
GRS is a drug combination of three active components including ginsenoside Rb1, ruscogenin and schisandrin. It derived from the well-known TCM formula ShengMai preparations, a widely used traditional Chinese medicine for the treatment of cardiovascular diseases in clinic. The present study explores the cardioprotective effects of GRS on myocardial ischemia/reperfusion (MI/R) injury compared with ShengMai preparations and investigates the underlying mechanisms. GRS treatment significantly attenuated MI/R injury and exhibited similar efficacy as Shengmai preparations, as evidenced by decreased myocardium infarct size, ameliorated histological features, the decrease of LDH production and improved cardiac function, and also produced a significant decrease of apoptotic index...
November 21, 2016: Scientific Reports
Anxin Wang, Zhaoping Su, Xiaoxue Liu, Yuling Yang, Shuohua Chen, Suzhen Wang, Yanxia Luo, Xiuhua Guo, Xingquan Zhao, Shouling Wu
BACKGROUND: Metabolic syndrome (MetS) is correlated with arterial stiffness and can be evaluated by brachial-ankle pulse wave velocity (baPWV). We investigated potential associations between MetS and baPWV in a Chinese community population. METHODS: The community-based Asymptomatic Polyvascular Abnormalities in Community study examined asymptomatic polyvascular abnormalities in a Chinese population aged ≥40 years. The relationship between MetS and its components and baPWV was analyzed by multivariate logistic and linear regression models...
November 18, 2016: BMC Cardiovascular Disorders
Xiaoxue Zhang
No abstract text is available yet for this article.
November 17, 2016: Protein & Cell
Qiaofeng Song, Xiaoxue Liu, Wenhua Zhou, Xizhu Wang, Shouling Wu
Using a large longitudinal data set spanning 4 years, we examined whether a change in self-reported sleep duration is associated with metabolic syndrome (MetS). Current analysis included 15,753 participants who were free of MetS during both 2006-2007 and 2010-2011. Sleep duration was categorized into seven groups: ≤5.5 h, 6.0-6.5 h, 7.0 h, 7.5-8.0 h, ≥8.5 h, decrease ≥2 h, and increase ≥2 h. Cox proportional hazards models were used to calculate hazard ratios (HRs) and their confidence intervals (CI) for MetS, according to sleep duration...
November 18, 2016: Scientific Reports
Zongshi Qin, Yulong Ding, Jiani Wu, Jing Zhou, Likun Yang, Xiaoxu Liu, Zhishun Liu
INTRODUCTION: Degenerative lumbar spinal stenosis (DLSS) is a major public health problem and the primary reason why older adults seek lumbar spine surgery. Acupuncture may be effective for DLSS, but the evidence supporting this possibility is still limited. METHODS AND ANALYSIS: A total of 80 participants with DLSS will be randomly allocated to either an acupuncture group or a sham acupuncture (SA) group at a ratio of 1:1. 24 treatments will be provided over 8 weeks...
November 16, 2016: BMJ Open
Xiaoxu Gang, Wenliang Qian, Tianlei Zhang, Xinxin Yang, Qingyou Xia, Daojun Cheng
Aurora B kinase, a member of serine/threonine kinase family, is the catalytic subunit of the chromosomal passenger complex and is essential for chromosome alignment, chromosome segregation, and cytokinesis during mitosis. Here, we cloned the full-length cDNA sequence of silkworm Aurora B (BmAurB) gene and predicted that BmAurB protein contains a conserved S_TKc domain. Phylogenetic analysis between BmAurB and other Aurora kinases indicates that Aurora kinases may have evolved after separation between mammalian and insect, and prior to radiation of either mammalian or insects...
November 9, 2016: Gene
Jue Liu, Ming Zhu, Xue Xia, Yuliang Huang, Qunfeng Zhang, Xiaoxu Wang
Jumonji domain-containing protein 1A (JMJD1A) plays a key role in the development and progression of several cancers. Here, we showed that the expression of JMJD1A is increased in cervical cancer cells and tissues, and that suppression of JMJD1A inhibits proliferation, migration, and invasion of cervical cancer cells. JMJD1A induced transcription of c-Myc, which is essential for cervical cancer growth and progression. Clinical data showed that JMJD1A expression correlated with lymph node metastasis (P=0.031) and FIGO stage (P=0...
November 8, 2016: Oncotarget
Peng Liang, Zhigang Song, Demeng Chen, Ruixia Linghu, Yingzhe Wang, Xingyang Zhang, Xiaoxue Kou, Junlan Yang, Shunchang Jiao
GINS2, a subunit of GINS complex, is critical for the initiation of DNA replication and DNA replication fork progression. The expression of GINS2 is misregulated in many malignant tumors, such as leukemia, breast cancer and melanoma. However, the role of GINS in breast cancer remains poorly characterized. We investigate the possible effect and particular mechanism of GINS in breast cancer cells. We showed that expression of GINS2 is enriched in triple negative breast cancer (TNBC) cell lines. Furthermore, GINS2 knockdown decreased the growth, invasive ability and stem-like property of TNBC cells...
November 6, 2016: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
Qiaofeng Song, Xiaoxue Liu, Wenhua Zhou, Xizhu Wang, Shouling Wu
Evidence suggests short or long sleep duration is associated with a higher risk of diabetes. Using a large longitudinal data set spanning 2 years, we examined whether a change in sleep duration is associated with diabetes.Current analysis included 56,588 participants who were free of diabetes during both 2006-2007 (exam1) and 2008-2009 (exam2). Sleep duration was categorized into 7 groups: ≤5.5 hours, 6.0 to 6.5 hours, 7.0 hours, 7.5 to 8.0 hours, ≥8.5 hours, decrease ≥2 hours, and increase ≥2 hours...
November 2016: Medicine (Baltimore)
Xiaoxue Wu, Shan Sun, Yuhui Wang, Jiali Zhu, Kai Jiang, Yumin Leng, Qinghai Shu, Hengwei Lin
Mitochondria, the power generators in cell, are a primary organelle of oxygen consumption and a main source of reactive oxygen/nitrogen species (ROS/RNS). Peroxynitrite (ONOO(-)), known as a kind of RNS, has been considered to be a significant factor in many cell-related biological processes, and there is great desire to develop fluorescent probes that can sensitively and selectively detect peroxynitrite in living cells. Herein, we developed a fluorescent carbon-dots (C-dots) based mitochondria-targetable nanoprobe with high sensitivity and selectivity for peroxynitrite sensing in living cells...
October 24, 2016: Biosensors & Bioelectronics
Jianyi Chen, Wei Tang, Bingbing Tian, Bo Liu, Xiaoxu Zhao, Yanpeng Liu, Tianhua Ren, Wei Liu, Dechao Geng, Hu Young Jeong, Hyeon Suk Shin, Wu Zhou, Kian Ping Loh
Large-sized MoS2 crystals can be grown on SiO2/Si substrates via a two-stage chemical vapor deposition method. The maximum size of MoS2 crystals can be up to about 305 μm. The growth method can be used to grow other transition metal dichalcogenide crystals and lateral heterojunctions. The electron mobility of the MoS2 crystals can reach ≈30 cm(2) V(-1) s(-1), which is comparable to those of exfoliated flakes.
August 2016: Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
Xiaoxu He, Heye Zhang, Mark Landis, Manas Sharma, James Warrington, Shuo Li
As a common disease in the elderly, neural foramina stenosis (NFS) brings a significantly negative impact on the quality of life due to its symptoms including pain, disability, fall risk and depression. Accurate boundary delineation is essential to the clinical diagnosis and treatment of NFS. However, existing clinical routine is extremely tedious and inefficient due to the requirement of physicians' intensively manual delineation. Automated delineation is highly needed but faces big challenges from the complexity and variability in neural foramina images...
October 29, 2016: Medical Image Analysis
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