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https://www.readbyqxmd.com/read/29751137/transferring-and-calibrating-safety-performance-functions-among-multiple-states
#1
Ahmed Farid, Mohamed Abdel-Aty, Jaeyoung Lee
Safety performance functions (SPFs), statistical regression models, by predicting traffic crash counts by crash type, severity and facility type, aid traffic engineers in the process of identifying high frequency crash locations. Developing SPFs requires the collection and processing of traffic, crash, road design and other characteristics' data. Jurisdictional agencies may choose not to develop their own SPFs and cut back on their resources by adopting SPFs provided by the national Highway Safety Manual (HSM)...
May 8, 2018: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/29727492/first-person-john-byrd-md-this-ohio-state-university-researcher-has-been-developing-transformative-treatments-for-patients-with-chronic-lymphocytic-leukemia-and-now-is-setting-his-sights-on-individuals-with-acute-myeloid-leukemia
#2
https://www.readbyqxmd.com/read/29723603/histology-of-colorectal-adenocarcinoma-with-double-somatic-mismatch-repair-mutations-is-indistinguishable-from-those-caused-by-lynch-syndrome
#3
Jessica A Hemminger, Rachel Pearlman, Sigurdis Haraldsdottir, Deborah Knight, Jon Gunnlaugur Jonasson, Colin C Pritchard, Heather Hampel, Wendy L Frankel
Lynch syndrome (LS) is the most common form of hereditary colon cancer (CRC). Germline mutations in the mismatch repair (MMR) genes MLH1, MSH2 (EPCAM), MSH6, and PMS2, followed by a second hit to the remaining allele leads to cancer development. Universal tumor screening for LS is routinely performed on CRC, and screening has identified patients with unexplained MMR deficiency that lack MLH1 methylation and a germline mutation. Tumor sequencing has since identified double somatic (DS) mutations in the MMR gene corresponding with the absent protein in 69% of these patients...
April 30, 2018: Human Pathology
https://www.readbyqxmd.com/read/29709522/feasibility-and-preliminary-validation-of-an-online-version-of-the-ohio-state-university-traumatic-brain-injury-identification-method
#4
Anthony H Lequerica, Christian Lucca, Nancy D Chiaravalloti, Irene Ward, John D Corrigan
OBJECTIVE: To test the feasibility and validity of an online version of an established interview designed to determine a lifetime history of traumatic brain injury. DESIGN: Cross-sectional SETTING: General community PARTICIPANTS: A volunteer sample of 265 individuals from the general population across the U.S. INTERVENTIONS: Not applicable MAIN OUTCOME MEASURE(S): Online version of the Ohio State University Traumatic Brain Injury Identification Method, Rivermead Postconcussion Symptoms Questionnaire (RPQ), PROMIS Cognitive Concerns Scale RESULTS: The measure was completed by 89...
April 27, 2018: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/29696598/the-personal-social-networks-of-resettled-bhutanese-refugees-during-pregnancy-in-the-united-states-a-social-network-analysis
#5
Diana M Kingsbury, Madhav P Bhatta, Brian Castellani, Aruna Khanal, Eric Jefferis, Jeffery S Hallam
Women comprise 50% of the refugee population, 25% of whom are of reproductive age. Female refugees are at risk for experiencing significant hardships associated with the refugee experience, including after resettlement. For refugee women, the strength of their personal social networks can play an important role in mitigating the stress of resettlement and can be an influential source of support during specific health events, such as pregnancy. A personal social network analysis was conducted among 45 resettled Bhutanese refugee women who had given birth within the past 2 years in the Akron Metropolitan Area of Northeast Ohio...
April 25, 2018: Journal of Community Health
https://www.readbyqxmd.com/read/29688032/setting-up-an-epathology-service-at-cleveland-clinic-abu-dhabi-joint-collaboration-with-cleveland-clinic-united-states
#6
Ayoub Nahal, Crystal Mildred O Batac, Renee J Slaw, Thomas W Bauer
CONTEXT: - The production of whole slide images is the most advanced form of digital pathology, in which a high-resolution digital scanner is used to rapidly scan glass microscope slides and produce a computer-generated whole slide image that can be saved, stored in a network-attached storage device, and accessed through slide management software within the hospital domain and remotely by authorized users. Digital transformation of glass slides has revolutionized the practice of anatomic pathology by facilitating and expediting consultative services, improving clinical workflow, and becoming an indispensable tool in education and research...
April 24, 2018: Archives of Pathology & Laboratory Medicine
https://www.readbyqxmd.com/read/29683125/factors-associated-with-poor-sleep-in-older-women-diagnosed-with-breast-cancer
#7
Janine Overcash, Alai Tan, Keya Patel, Anne M Noonan
OBJECTIVES: To determine the relationship among gait, grip strength, cognition, depression, pain, and fatigue, and to identify which variables are most predictive of poor sleep. SAMPLE & SETTING: 60 women with breast cancer aged 69 years or older who were receiving treatment in the Senior Adult Oncology Program at the James Cancer Hospital at the Ohio State University. METHODS & VARIABLES: The variables were gait and grip strength (functional domains), cognition, depression, pain, and fatigue...
May 1, 2018: Oncology Nursing Forum
https://www.readbyqxmd.com/read/29679599/mortality-in-pulmonary-arterial-hypertension-patients-treated-with-continuous-prostanoids
#8
S D Bartolome, N Sood, T S Shah, K Styrvoky, F T Torres, K M Chin
INTRODUCTION: Parenteral prostanoids are considered the treatment of choice for patients with severe pulmonary arterial hypertension (PAH). Prognostic studies for patients treated in the modern era are limited. METHODS: In this retrospective cohort study, patients initiating IV epoprostenol or IV or SC treprostinil therapy for PAH from 2007-2016 at UT Southwestern, Dallas, TX and Ohio State University, Columbus, OH were included. Transplant-free survival was assessed from the time of IV/SC initiation and from the time of first follow-up...
April 18, 2018: Chest
https://www.readbyqxmd.com/read/29658843/perceptions-of-midwestern-crop-advisors-and-growers-on-foliar-fungicide-adoption-and-use-in-maize
#9
Paul Esker, Denis Anthony Shah, Carl A Bradley, Shawn P Conley, Pierce A Paul, Alison Robertson
Foliar fungicide use in hybrid maize in the United States was rare before 2000. The decade from 2000 to 2010 saw foliar fungicides increasingly applied to maize in the absence of appreciable disease pressure, a practice seemingly at odds with integrated pest management philosophy. Yet, it is commonly believed that growers do not employ management strategies unless there are perceived benefits. Maize (corn) growers (CGs) and certified crop advisors (CCAs) across four Midwestern states (Iowa, Illinois, Ohio and Wisconsin) were surveyed to better understand their practices, values and perceptions concerning the use of foliar fungicides during 2005 to 2009...
April 16, 2018: Phytopathology
https://www.readbyqxmd.com/read/29651918/updated-report-on-incidence-of-infusion-site-reactions-associated-with-peripheral-intravenous-administration-of-fosaprepitant
#10
Eric Chau, Jordan Lundberg, Gary Phillips, Michael Berger, Robert Wesolowski
Purpose Fosaprepitant (Emend®) is an antiemetic frequently used for the prevention of chemotherapy-induced nausea and vomiting. We previously documented an overall 28.7% incidence of infusion-site reactions in patients receiving fosaprepitant via peripheral venous access. These data resulted in a practice change within our institution; fosaprepitant is administered in more dilute concentrations over 30 min to prevent these adverse events. This retrospective study explored the impact of this practice change on the incidence of infusion-site reactions...
January 1, 2018: Journal of Oncology Pharmacy Practice
https://www.readbyqxmd.com/read/29621925/transport-kinetics-of-chromium-in-perfused-human-placental-lobule-in-late-gestation-in-vitro-study
#11
B Al-Sannan, M Nandakumaran, J Al-Harmi, M Al-Shammari, M Fouda
OBJECTIVE: Reports relating to maternal-fetal transport kinetics of chromium, an essential trace element in the human pregnancies are scanty. Hence, we thought it interesting to investigate the transport kinetics of this trace element in the human placenta in late gestation in vitro. METHODS: Human placentae were collected immediately after delivery from normal uncomplicated pregnancies. Chromium chloride solution (GFS Chem Inc, Ohio, USA) at 10 times the physiological concentrations and antipyrine (Sigma Chem Co...
April 5, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29618540/mental-condition-requirement-in-competency-to-stand-trial-assessments
#12
Andrew D Reisner, Jennifer L Piel
In Ohio, a criminal defendant is incompetent to stand trial only if "a present mental condition" renders him unable to understand the nature and objectives of the proceedings against him or to assist in his defense. Some forensic mental health evaluators have treated the mental-condition requirement as synonymous with, or similar to, the psychiatric condition required in the state's insanity criteria, which requires a "severe mental disease or defect." Yet the term mental condition does not appear in other areas of the state's criminal code or in the state's definition of a mental illness for purposes of civil commitment...
March 2018: Journal of the American Academy of Psychiatry and the Law
https://www.readbyqxmd.com/read/29611769/predictors-of-complications-in-patients-receiving-head-and-neck-free-flap-reconstructive-procedures
#13
Antoine Eskander, Stephen Kang, Ben Tweel, Jigar Sitapara, Matthew Old, Enver Ozer, Amit Agrawal, Ricardo Carrau, James W Rocco, Theodoros N Teknos
Objective To (1) determine the overall complication rate, wound healing, and wound infection complications and (2) identify preoperative, intraoperative, and postoperative predictors of these complications. Study Design Case series with chart review. Setting Tertiary academic cancer hospital. Subjects and Methods All head and neck free flap patients at The Ohio State University (2006-2012) were assessed. Multivariable logistic regression assessed the impact of patient factors, flap and wound factors, and intraoperative factors on the aforementioned quality metric outcomes...
April 1, 2018: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29611730/prevalence-of-human-noroviruses-in-commercial-food-establishment-bathrooms
#14
Cortney M Leone, Muthu Dharmasena, Chaoyi Tang, Erin DiCAPRIO, Yuanmei Ma, Elbashir Araud, Hannah Bolinger, Kitwadee Rupprom, Thomas Yeargin, Jianrong Li, Donald Schaffner, Xiuping Jiang, Julia Sharp, Jan Vinjé, Angela Fraser
Although transmission of human norovirus in food establishments is commonly attributed to consumption of contaminated food, transmission via contaminated environmental surfaces, such as those in bathrooms, may also play a role. Our aim was to determine the prevalence of human norovirus on bathroom surfaces in commercial food establishments in New Jersey, Ohio, and South Carolina under nonoutbreak conditions and to determine characteristics associated with the presence of human norovirus. Food establishments (751) were randomly selected from nine counties in each state...
May 2018: Journal of Food Protection
https://www.readbyqxmd.com/read/29610676/pregnant-or-recently-pregnant-opioid-users-contraception-decisions-perceptions-and-preferences
#15
Rebecca L Fischbein, Bethany G Lanese, Lynn Falletta, Kelsey Hamilton, Jennifer A King, Deric R Kenne
Background: Multiple factors are linked to extremely high unintended pregnancy rates among women who use opioids, including various barriers to contraception adherence. These include patient level barriers such as lack of knowledge and education about highly effective contraception, and potential provider barriers. Using a mixed-methods framework to examine the contraception-related perceptions and preferences of opioid using women is a necessary next step to understanding this phenomenon...
2018: Contraception and reproductive medicine
https://www.readbyqxmd.com/read/29606997/characterization-of-the-2016-2017-dermatology-standardized-letter-of-recommendation
#16
Rebecca F Wang, Myron Zhang, Allireza Alloo, Thomas Stasko, Jordan E Miller, Jessica A Kaffenberger
Objective: We aimed to analyze the reformatted standard letter of recommendation (SLOR) for dermatology residents to examine trends in grading and content based on the positions of the letter writers, their backgrounds, and their relationship with the applicant, as well as to evaluate the SLOR's ability to discriminate applicants. Design: This was a retrospective characterization study of dermatology SLORs from the 2016-17 application cycle. Setting: We examined SLORs received by The Ohio State University, the University of Oklahoma, and Hofstra University Northwell Health dermatology residency programs...
March 2018: Journal of Clinical and Aesthetic Dermatology
https://www.readbyqxmd.com/read/29589978/zap70-expression-enhances-chemokine-driven-chronic-lymphocytic-leukemia-cell-migration-and-arrest-by-valency-regulation-of-integrins
#17
Julia M Laufer, Ruth Lyck, Daniel F Legler
The ζ-associated protein of 70 kDa (ZAP70) is expressed in the aggressive form of B-cell chronic lymphocytic leukemia (CLL). Moreover, the integrin very late antigen (VLA)-1 is highly expressed on subtypes of CLL that are associated with high proliferation rates in the lymph node context. We herein identify a critical role for ZAP70 in chemokine-mediated, inside-out signaling to integrins in trisomy 12 carrying Ohio State University-CLL cell lines derived from a patient with previously treated CLL. We found that ZAP70-positive CLL cells migrated significantly better toward ligands of the lymph node homing chemokine receptors CCR7 and CXCR4 compared with ZAP70-negative cells...
March 28, 2018: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
https://www.readbyqxmd.com/read/29582708/peritoneal-and-scrotal-carcinomas-of-unknown-origin-in-two-bovine-calves
#18
Kelsey A Brakel, Grace VanHoy, Austin Hinds, Justin Breitbach, Christopher Premanandan, Rebecca Kohnken
Two unrelated bovine beef calves, aged 2 mo and 3 mo, were presented to The Ohio State University Veterinary Medical Center because of scrotal swelling and abdominal distension. On postmortem examination, there was abundant peritoneal fluid and numerous small friable masses covering all peritoneal surfaces and extending into the scrotum via the tunica vaginalis, with no identifiable primary neoplasm. Based on light microscopy, differential diagnoses included malignant mesothelioma and anaplastic carcinoma. Immunohistochemically, the neoplasms labeled positive for cytokeratin, and negative for vimentin and calretinin...
March 1, 2018: Journal of Veterinary Diagnostic Investigation
https://www.readbyqxmd.com/read/29580916/influences-on-intentions-to-place-long-acting-reversible-contraceptives-a-pilot-study-comparing-by-provider-specialty-in-ohio
#19
Charee Thompson, Jane Broecker, Maggie Dade, Kelly Nottingham
STUDY OBJECTIVE: According to the American Academy of Pediatrics (AAP), pediatricians are to counsel and provide LARCs as first-line-of-defense contraceptives because they are the most effective. We wanted to explore positive influences on LARC placement for pediatricians, particularly when compared to providers in other specialties who care for women. DESIGN: Survey methods with data analyzed using analyses of variance and general linear models in statistical software SPSS 24...
March 23, 2018: Journal of Pediatric and Adolescent Gynecology
https://www.readbyqxmd.com/read/29570712/shale-gas-activity-and-increased-rates-of-sexually-transmitted-infections-in-ohio-2000-2016
#20
Nicole C Deziel, Zoe Humeau, Elise G Elliott, Joshua L Warren, Linda M Niccolai
BACKGROUND: The growing shale gas ("fracking") industry depends on a mobile workforce, whose influx could have social impacts on host communities. Sexually transmitted infections (STIs) can increase through sexual mixing patterns associated with labor migration. No prior studies have quantified the relationship between shale gas activity and rates of three reportable STIs: chlamydia, gonorrhea, and syphilis. METHODS: We conducted a longitudinal, ecologic study from 2000-2016 in Ohio, situated in a prolific shale gas region in the United States (US)...
2018: PloS One
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