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Cancer, surgical oncology, aesthetic surgery, reconstructive surgery, plastic surgery, breast cancer,

Yoshiko Toyoda, Karel-Bart Celie, Jonathan T Xu, Justin S Buro, Julia Jin, Alexandra J Lin, Kristy A Brown, Jason A Spector
INTRODUCTION: Obesity is a known risk factor for the development and prognosis of breast cancer. Adipocytes have been identified as a source of exogenous lipids in other cancer types and may similarly provide energy to fuel malignant survival and growth in breast cancer. This relationship is of particular relevance to plastic surgery, because many reconstructions after oncologic mastectomy achieve optimal aesthetics and durability using adjunctive autologous fat transfer (AFT). Despite the increasing ubiquity and promise of AFT, many unanswered questions remain, including safety in the setting of breast cancer...
April 2018: Annals of Plastic Surgery
Rajiv Dave, Rachel O'Connell, Tim Rattay, Zoe Tolkien, Nicola Barnes, Joanna Skillman, Paula Williamson, Elizabeth Conroy, Matthew Gardiner, Adrian Harnett, Ciara O'Brien, Jane Blazeby, Shelley Potter, Chris Holcombe
INTRODUCTION: Immediate breast reconstruction (IBR) is routinely offered to improve quality of life for women with breast cancer requiring a mastectomy, but there are concerns that more complex surgery may delay the delivery of adjuvant oncological treatments and compromise long-term oncological outcomes. High-quality evidence, however, is lacking. iBRA-2 is a national prospective multicentre cohort study that aims to investigate the effect of IBR on the delivery of adjuvant therapy. METHODS AND ANALYSIS: Breast and plastic surgery centres in the UK performing mastectomy with or without (±) IBR will be invited to participate in the study through the trainee research collaborative network...
October 7, 2016: BMJ Open
Gianluca Franceschini, Alejandro Martin Sanchez, Giuseppe Visconti, Alba Di Leone, Sabatino D'Archi, Antonino Mulè, Angela Santoro, Marzia Salgarello, Riccardo Masetti
Oncoplastic surgery of the breast has generated great excitement over the past years and has become an integrated component of the surgical treatment of breast cancer. Oncoplastic procedures (OPP) associate the best surgical oncologic principles to achieve wide tumor-free margins with the best principles of plastic surgery to optimize cosmetic outcomes. So, a number of conventional mammoplasty techniques have been adapted to allow reconstruction of resection defects with parenchymal flaps using a variety of different approaches...
2016: Annali Italiani di Chirurgia
Riaz A Agha, Alexander J Fowler, Thomas E Pidgeon, Georgina Wellstead, Dennis P Orgill
INTRODUCTION: One in eight women will develop breast cancer in their lifetime. Reconstruction is routinely offered to patients and can be autologous and/or implant based. One area of growing interest in autologous fat grafting (AFG). Our group recently published a systematic review and meta-analysis of this topic which showed 51 different outcomes were being utilized in the published literature, with substantial heterogeneity in their definitions. METHODS AND ANALYSIS: A Delphi consensus exercise amongst key stakeholders will be conducted using the long list of 51 outcomes generated through our previous work...
July 2016: International Journal of Surgery
Paolo Veronesi, Francesca De Lorenzi, Pietro Loschi, Mario Rietjens, Umberto Veronesi
UNLABELLED: Breast augmentation is the most common cosmetic surgery in the United States, and thousands of augmented patients develop breast cancer each year. The possible effects of implants on cancer incidence, diagnosis, and treatment usually generate a disarming confusion. The present paper represents an update of the more recent oncologic and surgical strategies, aiming to support plastic and general surgeons in such challenging aspects. Several aspects of breast cancer management in augmented women are investigated, including (1) risk estimation and cancer characteristics, stage at diagnosis, and prognosis; (2) cancer diagnosis with clinical examination, mammography, ultrasound, and magnetic resonance imaging; (3) cancer treatment including breast conservation, intraoperative radiotherapy, sentinel node biopsy and mastectomy, and reconstruction...
April 2016: Aesthetic Plastic Surgery
Gianluca Franceschini, Alejandro Martin Sanchez, Giuseppe Visconti, Alba Di Leone, Marzia Salgarello, Riccardo Masetti
UNLABELLED: Oncoplastic surgery of the breast has generated great excitement over the past years and has become an integrated component of the surgical treatment of breast cancer. Oncoplastic procedures (OPP) associate the best surgical oncologic principles to achieve wide tumor-free margins with the best principles of plastic surgery to optimize cosmetic outcomes. Thanks to oncoplastic techniques, the role of breast conserving surgery (BCS) has been extended to include a group of patients who would otherwise require mastectomy to achieve adeguate tumor clearance...
2015: Annali Italiani di Chirurgia
Bartłomiej Noszczyk
Over the last decade autologous fat from subcutaneous tissue has been used by plastic surgeons for face volumization. It has also been used with growing frequency for aesthetic breast enhancement. Currently, experts in this field are becoming increasingly aware of the potential of fat for breast reconstruction. However, the safety of fat transfers to post-mastectomy defects has been called into question in recent debates due to the, albeit rare, observations of their possible influence on local cancer recurrence...
2015: Annals of Transplantation: Quarterly of the Polish Transplantation Society
Danielle H Rochlin, Ah-Reum Jeong, Leah Goldberg, Timothy Harris, Kriti Mohan, Stella Seal, Joe Canner, Justin M Sacks
BACKGROUND AND OBJECTIVES: The effect of postmastectomy radiation therapy (PMRT) on immediately reconstructed abdominal wall-based tissue remains imprecisely defined. We evaluated evidence from all fields involved in care of the breast cancer patient in order to advance a unified recommendation regarding this therapeutic sequence. METHODS: We performed a MEDLINE and manual reference search to identify studies of PMRT with immediate autologous breast reconstruction...
March 2015: Journal of Surgical Oncology
Gustavo Zucca-Matthes, Andrea Manconi, Rene Aloísio da Costa Viera, Rodrigo Augusto Depieri Michelli, Angelo do Carmo Silva Matthes
Over time, surgical techniques have advanced to the point where oncological safety and aesthetic outcomes are the pillars of contemporary breast surgery. Variations of mastectomy came up and started allowing the oncological safety and the possibility of an immediate breast reconstruction. Nowadays the association between plastic surgical techniques and mastectomy with immediate breast reconstruction is one of the best alternatives to treat breast cancer and also improved overall aesthetic outcomes and favors the achievement of contralateral breast symmetry...
May 2013: Gland Surgery
Mirosław Dobrut, Adam Maciejewski, Stanisław Półtorak
UNLABELLED: The aim of the study was to evaluate the efficacy of different microvascular techniques in breast reconstruction with the analysis of postoperative complications. The additional goal of the study is to analyze the quality of life of patients after microvascular breast reconstruction in comparison to the control group of patients who underwent only mastectomy without any reconstructive procedures. Also the algorithm of breast reconstruction is presented as the result of own experiences...
January 2013: Polski Przeglad Chirurgiczny
Zoltán Mátrai, Pál Pesthy, Gusztáv Gulyás, Eva Szabó, Alexandra Bartal, Miklós Kásler
Autologous fat transplantation is often used in aesthetic plastic surgery, and is recently becoming increasingly popular in the reconstruction of soft tissue defects following oncological surgery. A still not standardized technique of fat transplantation for breast cancer reconstruction is rapidly getting popular. The procedure is not a passive volume replacement, but transplantation of biologically active tissue bearing endocrine, paracrine, exocrine functions and containing fat-derived stem cells, which in the tumorous environment raises many questions in relation to the oncological safety and diagnostic follow-up...
November 18, 2012: Orvosi Hetilap
Marek Dobke
An overview of advances and controversies in the management of breast cancer and their impact on plastic breast surgery is presented, including prophylactic mastectomy for women at high risk of breast cancer, size and location of the primary tumor and feasibility of breast-conserving surgery and oncoplastic approach, the management of the axilla, postmastectomy radiation and chemotherapy, emerging breast reconstructive techniques and cancer risk, and oncological follow-up and imaging of the reconstructed breast...
October 2012: Clinics in Plastic Surgery
David A Kelly, Benjamin C Wood, Gregory M Knoll, Shu C Chang, John C Crantford, Gaurav D Bharti, Edward A Levine, James T Thompson
Breast conservation therapy (BCT) has evolved as a favorable approach to the management of early-stage breast cancer. Shortcomings of BCT include the potential need for re-excision in the event of positive tumor margins as well as the untoward sequelae of radiation therapy. Both of those factors have led to a substantial proportion of patients undergoing BCT who ultimately report suboptimal aesthetic outcomes. Application of plastic surgery principles to the management of this patient subset has been shown to be beneficial from both an oncologic and cosmetic perspective...
May 2012: Annals of Plastic Surgery
Cicero Urban, Rubens Lima, Eduardo Schunemann, Cleverton Spautz, Iris Rabinovich, Karina Anselmi
Oncoplastic surgery (OP) represents a major advance in breast cancer surgery. It is based on three principles: ideal oncology surgery with free margins and adequate local control of disease, immediate breast reconstruction and symmetry, with the transposition of plastic surgery techniques into breast cancer surgery. Its original focus was to improve the quality of life of patients undergoing oncological treatments that can be more effective from the aesthetic-functional point of view than the traditional breast conserving techniques...
October 2011: Breast: Official Journal of the European Society of Mastology
Gail S Lebovic
Oncoplastic surgery combines the principles of surgical oncology with those of plastic and reconstructive surgery. The intent is to use established techniques from each field in order to provide adequate tumor resection without compromise while optimizing aesthetic outcomes. This patient-centered approach requires a multidisciplinary preoperative evaluation in order to devise a comprehensive surgical plan and coordinate adjuvant treatment as needed. This article provides a historical perspective as well as insight into various creative techniques for breast cancer surgery...
July 2010: Surgical Oncology Clinics of North America
László Romics, Eva Weiler-Mithoff, Timothy G Cooke, W David George
The future challenge of breast surgery, the so-called oncoplastic approach is reviewed in this article. The authors discuss the most frequently applied surgical techniques as well as their indications. Medline and pubmed search was carried out using the following keywords and cross-references: "oncoplastic breast surgery", "breast reconstruction", "breast conserving surgery" and "reduction mammoplasty". Original and review papers published in English language and their references were included. In the literature surprisingly, a large variety of breast oncoplastic surgical procedures has been described...
February 2008: Magyar Sebészet
Scott L Spear, Christopher V Pelletiere, Andrew J Wolfe, Theodore N Tsangaris, Marie F Pennanen
As the inclusion criteria for breast conservation therapy have continued to evolve to include lower quadrant tumors, very large breasts, and central tumors, the potential for significant disfigurement after breast conservation therapy has also increased. This has led some centers to develop coordinated oncology-plastic surgery approaches to ensure both adequate cancer resection and aesthetic appearance to the breasts. The authors applied this principle to a specific group of breast cancer patients--women with macromastia--who would benefit from reduction mammaplasty...
March 2003: Plastic and Reconstructive Surgery
C Papp, G Wechselberger, T Schoeller
Breast-conserving therapy, which aims to reduce trauma by preserving as much of a patient's natural appearance as possible, does not necessarily lead to an optimal cosmesis. We hypothesized that combining plastic and oncologic surgeries would greatly reduce the physical and psychological traumas and produce an optimal cosmesis without impairing the oncologic outcome. We performed breast reconstruction on 40 cancer patients. Of those 40 patients, 15 received combined plastic and oncologic surgeries. Procedures depended on breast size: mammareduction plasty in cases with sufficient volume, and reconstruction using myocutaneous latissimus dorsi flaps for those with less volume...
November 1998: Plastic and Reconstructive Surgery
J Y Petit, A Lehmann
The surgical treatment of breast cancer has changed dramatically since the last twenty years. Radical and super-radical mastectomy are almost no longer indicated except in certain cases of local recurrences. Breast saving procedures are the best indication for small tumors. And the psychological impact of the different treatments including radiotherapy and chemotherapy is considered as an important issue. Therefore, plastic surgeons are more and more frequently called upon to restore the breast appearance using some technique of breast reconstruction or to improve the bad results of a conservative treatment...
February 1996: Bulletin de L'Académie Nationale de Médecine
T G Frazier, R B Noone
In January 1977, the authors developed a protocol to test the advisability and feasibility of immediate simultaneous reconstruction in the treatment of primary carcinoma of the breast. Initial concerns included the morbidity of the procedure, the potential for compromise of cure and of adjuvant cancer therapy, and the aesthetic acceptability of immediate reconstruction both to the patient and to the surgeon. All patients were seen preoperatively by both the oncologic surgeon (T.G.F.) and the plastic and reconstructive surgeon, (R...
March 15, 1985: Cancer
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