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https://www.readbyqxmd.com/read/28196158/hybrid-implants-in-healthy-and-periodontally-compromised-patients-a-preliminary-clinical-and-radiographic-study
#1
Sergio Spinato, Fabio Bernardello, Paolo Sassatelli, Davide Zaffe
This preliminary clinical and radiographic study examined the survival of, the marginal bone loss (MBL) around, and the influence of prosthetic abutment height (AH) on MBL around hybrid implants placed in two groups of partially edentulous patients: healthy (HPs) and periodontally compromised (PCPs) patients. A total of 93 patients requiring single or multiunit implant restoration, in the mandible or maxilla, were treated while undergoing cement-retained prosthetic restoration. A total of 54 implants (35 in the maxilla and 19 in the mandible) were placed in 45 HPs, and 56 implants (31 in the maxilla and 25 in the mandible) in 48 PCPs...
March 2017: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/28155896/hysteretic-photochromic-switching-of-eu-mg-defects-in-gan-links-the-shallow-transient-and-deep-ground-states-of-the-mg-acceptor
#2
A K Singh, K P O'Donnell, P R Edwards, K Lorenz, M J Kappers, M Boćkowski
Although p-type activation of GaN by Mg underpins a mature commercial technology, the nature of the Mg acceptor in GaN is still controversial. Here, we use implanted Eu as a 'spectator ion' to probe the lattice location of Mg in doubly doped GaN(Mg):Eu. Photoluminescence spectroscopy of this material exemplifies hysteretic photochromic switching (HPS) between two configurations, Eu0 and Eu1(Mg), of the same Eu-Mg defect, with a hyperbolic time dependence on 'switchdown' from Eu0 to Eu1(Mg). The sample temperature and the incident light intensity at 355 nm tune the characteristic switching time over several orders of magnitude, from less than a second at 12...
February 3, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28152010/comparison-of-corneal-epitheliotrophic-capacities-among-human-platelet-lysates-and-other-blood-derivatives
#3
Chien-Jung Huang, Yi-Chen Sun, Karen Christopher, Amy Shih-I Pai, Chia-Ju Lu, Fung-Rong Hu, Szu-Yuan Lin, Wei-Li Chen
PURPOSE: To evaluate the corneal epitheliotropic abilities of two commercialized human platelet lysates (HPLs) and to compare the results with other blood derivatives, including human peripheral serum (HPS) and bovine fetal serum (FBS). METHODS: In vitro, human corneal epithelial cells were incubated in various concentrations (0%, 3%, 5% and 10%) of blood derivatives. Two commercialized HPLs, including UltraGRO TM (Helios, Atlanta, GA) and PLTMax (Mill Creek, Rochester, MI), were tested and compared with HPS and FBS...
2017: PloS One
https://www.readbyqxmd.com/read/28149709/evaluation-of-a-health-promoting-schools-program-in-a-school-board-in-nova-scotia-canada
#4
Jessie-Lee D McIsaac, Tarra L Penney, Nicole Ata, Lori Munro-Sigfridson, Jane Cunningham, Paul J Veugelers, Kate Storey, Arto Ohinmaa, Sara F L Kirk, Stefan Kuhle
A Health promoting schools (HPS) approach aims to make schools a healthy place through a holistic approach that promotes a supportive 'school ethos' and emphasizes improvements in physical, social, and emotional well-being and educational outcomes. A HPS initiative in rural Nova Scotia (Canada) provided an opportunity for a population-level natural experiment. This study investigated student well-being and health behaviours between schools with and without HPS implementation and schools with high and low school ethos scores...
March 2017: Preventive Medicine Reports
https://www.readbyqxmd.com/read/28145084/an-exploratory-study-into-the-unmet-supportive-needs-of-people-diagnosed-with-cirrhosis-in-queensland-australia
#5
Patricia C Valery, Paul J Clark, Steven M McPhail, Tony Rahman, Kelly Hayward, Jennifer Martin, Leigh Horsfall, Michael L Volk, Richard Skoien, E Powell
BACKGROUND: Many patients with cirrhosis follow complex medication and dietary regimens and those with decompensated cirrhosis suffer debilitating complications. These factors impact on activities of daily living and quality of life. OBJECTIVE: To explore the concerns and challenges of people with cirrhosis and their use of support services. Also, to describe health professionals' (HP) perspectives of patients' concerns. METHODS: Cross-sectional study at a tertiary liver clinic involving 50 patients and 54 HPs...
February 1, 2017: Internal Medicine Journal
https://www.readbyqxmd.com/read/28144619/two-complex-cases-of-hermansky-pudlak-syndrome-highlight-a-potential-biologic-explanation-for-an-associated-crohn-s-disease-phenotype
#6
M Anthony Sofia, Atsushi Sakuraba, David T Rubin
Hermansky-Pudlak syndrome (HPS) is a rare autosomal recessive disorder characterized by oculocutaneous albinism and a lack of dense granules in platelets. HPS types 1 and 4 are associated with a granulomatous enterocolitis that is phenotypically indistinguishable from Crohn's disease. We present two cases of HPS-associated Crohn's disease phenotype in which the patients were refractory to standard medical management. The pathophysiology of HPS is mediated by single-gene defects that alter endosome trafficking, and we hypothesize that this mechanism leads to the observed association with a CD phenotype...
2017: ACG Case Reports Journal
https://www.readbyqxmd.com/read/28135658/an-exploration-of-australian-psychologists-role-in-assessing-women-considering-risk-reducing-or-contralateral-prophylactic-mastectomy
#7
Lucy Braude, Rebekah Laidsaar-Powell, Jemma Gilchrist, Laura Kirsten, Ilona Juraskova
OBJECTIVES: Given increasing rates of risk-reducing mastectomies (RRM) and contralateral prophylactic mastectomies (CPM), and the potentially significant psychological sequelae of this irreversible procedure, health professionals (HPs) regularly refer patients to psychologists for pre-operative assessment and support. This is the first study to provide qualitative insights from HPs into the role of psychologists who are working with women considering RRM or CPM. MATERIALS AND METHODS: 24 HPs (psychologists, surgeons, breast care nurses and genetic counsellors) experienced in treating patients before or after RRM/CPM completed semi-structured interviews (n = 15) or participated in a focus group (n = 10)...
January 27, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28127545/advanced-hepatic-fibrosis-in-fatty-liver-disease-linked-to-hyperplastic-colonic-polyp
#8
Mahmud Mahamid, Omar Abu-Elhija, Tarik Yassin, William Nseir
Aim. Our study aims to determine possible association between biopsy-proven nonalcoholic steatohepatitis (NASH) and hyperplastic polyps (HP) of the colon. Methods. A retrospective cohort observational study. All subjects underwent screening colonoscopy within two years. Data were extracted from the patient charts including demographic, anthropometric measurement, vital signs, underlying diseases, medical therapy, laboratory data, results of the liver biopsy with degree of fibrosis and necroinflammatory activity, the colonoscopy report, and the pathological report of the extracted polyp...
2017: Canadian Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28122870/multicenter-comparison-study-of-both-analytical-and-clinical-performance-across-4-roche-hcv-rna-assays-utilizing-different-platforms
#9
Johannes Vermehren, Evelyn Stelzl, Benjamin Maasoumy, Veronique Michel-Treil, Caterina Berkowski, Ed G Marins, Ellen E Paxinos, Enrique Marino, Heiner Wedemeyer, Christoph Sarrazin, Harald H Kessler
Antiviral treatment efficacy for chronic HCV infection is determined based on measurement of HCV RNA at specific time points throughout therapy by highly sensitive and accurate HCV RNA assays. This study evaluated the performance of two recently-developed real-time PCR HCV RNA assays, the cobas HCV for use on the cobas 6800/8800 systems (cobas 6800/8800 HCV) and the cobas HCV for use on the cobas 4800 system (cobas 4800 HCV) in comparison to two established assays, the COBAS AmpliPrep/COBAS TaqMan HCV Quantitative Test, version 2...
January 25, 2017: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/28118129/cde-perspectives-of-providing-new-onset-type-1-diabetes-education-using-formal-vignettes-and-simulation
#10
Neesha Ramchandani, Kim Johnson, Karen Cullen, Terri Hamm, Jean Bisordi, Susan Sullivan-Bolyai
Purpose The purpose of this article is to describe the 4 Parent Education Through Simulation-Diabetes (PETS-D) nurse certified diabetes educators' (CDEs) perspectives of teaching parents of children with newly diagnosed type 1 diabetes mellitus (T1DM) early diabetes management skills using formal vignettes and a human patient simulator/human patient simulation (HPS) to augment/enhance the teaching-learning process. Methods A qualitative descriptive approach was used. Four CDEs were interviewed by phone about their teaching experiences...
February 2017: Diabetes Educator
https://www.readbyqxmd.com/read/28118113/organ-doses-to-airline-passengers-screened-by-x-ray-backscatter-imaging-systems
#11
Elliott J Stepusin, Matthew R Maynard, Shannon E O'Reilly, Sadije Redzovic, Wesley E Bolch, David E Hintenlang, Thomas B Borak
Advanced imaging technologies (AIT) are being developed for passenger airline transportation. They are designed to provide enhanced security benefits by identifying objects on passengers that would not be detected by methodologies now used for routine surveillance. X-ray backscatter imaging is one AIT system being considered. Since this technology is based on scanning passengers with ionizing radiation, concern has been raised relating to the health risks associated with these exposures. Recommendations for standards of radiation safety have been proposed by the American National Standards Institute published in ANSI/HPS N43...
January 24, 2017: Radiation Research
https://www.readbyqxmd.com/read/28107625/gold-nanoshell-mediated-remote-myotube-activation
#12
Attilio Marino, Satoshi Arai, Yanyan Hou, Andrea Degl'Innocenti, Valentina Cappello, Barbara Mazzolai, Young-Tae Chang, Virgilio Mattoli, Madoka Suzuki, Gianni Ciofani
Mild heat stimulation of muscle cells within the physiological range represents an intriguing approach for the modulation of their functions. In this work, photothermal conversion was exploited to remotely stimulate striated muscle cells by using gold nanoshells (NS) in combination with near-infrared (NIR) radiation. Temperature increments of approximately 5°C were recorded by using an intracellular fluorescent molecular thermometer and were demonstrated to efficiently induce myotube contraction. The mechanism at the base of this phenomenon was thoroughly investigated and was observed to be a Ca2+-independent event directly involving actin-myosin interactions...
January 20, 2017: ACS Nano
https://www.readbyqxmd.com/read/28106253/massive-plasmablast-response-elicited-in-the-acute-phase-of-hantavirus-pulmonary-syndrome
#13
Marina García, Ayelén Iglesias, Verónica I Landoni, Carla Bellomo, Agostina Bruno, María Teresa Córdoba, Luciana Balboa, Gabriela C Fernández, María Del Carmen Sasiain, Valeria P Martínez, Pablo Schierloh
Beside its key diagnostic value, the humoral immune response is thought to play a protective role in hantavirus pulmonary syndrome. However, little is known about the cell source of these antibodies during ongoing human infection. Herein we characterized B-cell subsets circulating in Andes-virus-infected patients. A notable potent plasmablast (PB) response that increased 100-fold over the baseline levels was observed around 1 week after the onset of symptoms. These PB present a CD3(neg) CD19(low) CD20(neg) CD38(hi) CD27(hi) CD138(+/-) IgA(+/-) surface phenotype together with the presence of cytoplasmic functional immunoglobulins...
January 20, 2017: Immunology
https://www.readbyqxmd.com/read/28103211/notes-from-the-field-hantavirus-pulmonary-syndrome-in-a-migrant-farm-worker-colorado-2016
#14
Grace Marx, Kaylan Stinson, Monte Deatrich, Bernadette Albanese
HASH(0x42e0608)
20, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/28075530/dysregulation-of-pldn-pallidin-is-a-mechanism-for-platelet-dense-granule-deficiency-in-runx1-haplodeficiency
#15
G F Mao, L E Goldfinger, D C Fan, M P Lambert, G Jalagadugula, R Freishtat, A K Rao
BACKGROUND: Inherited RUNX1 haplodeficiency is associated with thrombocytopenia and platelet dysfunction. Dense granule (DG) deficiency is reported in patients with RUNX1 haplodeficiency, but the molecular mechanisms are unknown. Platelet mRNA expression profiling in a patient previously reported by us with a RUNX1 mutation and platelet dysfunction showed decreased expression of PLDN (BLOC1S6), which encodes for pallidin, a subunit of BLOC-1 (biogenesis of lysosome-related organelles complex-1) involved in granule biogenesis...
January 11, 2017: Journal of Thrombosis and Haemostasis: JTH
https://www.readbyqxmd.com/read/28069155/communicating-with-patients-from-minority-backgrounds-individual-challenges-experienced-by-oncology-health-professionals
#16
Kaaren J Watts, Bettina Meiser, Elvira Zilliacus, Rajneesh Kaur, Mona Taouk, Afaf Girgis, Phyllis Butow, David Goldstein, Sandra Hale, Astrid Perry, Sanchia K Aranda, David W Kissane
PURPOSE: Oncology health professionals (HPs) are increasingly required to care for patients from minority backgrounds. Yet many HPs have not had formal training in how to communicate effectively in culturally diverse settings. More information is needed about the challenges that oncology HPs face in communicating with minority patients to inform the content of formal training programs. This qualitative study aimed to identify oncology nurses' and oncologists' individual experiences and challenges in communicating with patients from minority backgrounds...
February 2017: European Journal of Oncology Nursing: the Official Journal of European Oncology Nursing Society
https://www.readbyqxmd.com/read/28058237/lessons-learnt-from-pilot-field-test-of-a-comprehensive-advocacy-program-to-support-health-promoting-schools-project-in-iran
#17
Towhid Babazadeh, Behrouz Fathi, Abdolreza Shaghaghi, Hamid Allahverdipour
Background: Health promoting schools (HPS) project is currently being used in Iran but many challenges still lie ahead. The present study aimed, to test feasibility of implementing a comprehensive advocacy program (CAP) to overcome the obstacles and problems associated with the consummation of school health programs based on the HPS framework. Methods: This quasi-experimental study was performed through recruiting all schools that were enrolled in the national HPS program and located in Jolfa as the intervention group and all of the schools situated in the East Azerbaijan province as control...
2017: Health Promotion Perspectives
https://www.readbyqxmd.com/read/28049344/changes-in-physical-activity-among-coronary-and-hypertensive-patients-a-longitudinal-study-using-the-health-action-process-approach
#18
P Steca, L Pancani, F Cesana, F Fattirolli, C Giannattasio, A Greco, M D'Addario, D Monzani, E R Cappelletti, M E Magrin, M Miglioretti, M Sarini, M Scrignaro, L Vecchio, C Franzelli
OBJECTIVES: Physical activity (PA) is a key factor in cardiovascular disease prevention. Through the Health Action Process Approach (HAPA), the present study investigated the process of change in PA in coronary patients (CPs) and hypertensive patients (HPs). DESIGN: Longitudinal survey study with two follow-up assessments at 6 and 12 months on 188 CPs and 169 HPs. MAIN OUTCOME MEASURES: Intensity and frequency of PA. RESULTS: A multi-sample analysis indicated the equivalence of almost all the HAPA social cognitive patterns for both patient populations...
January 4, 2017: Psychology & Health
https://www.readbyqxmd.com/read/28042141/prolonged-unexplained-hypoxemia-as-initial-presentation-of-cirrhosis-a-case-report
#19
Anand Puttappa, Kumaraswamy Sheshadri, Aurelie Fabre, Georgina Imberger, John Boylan, Silke Ryan, Masood Iqbal, Niamh Conlon
BACKGROUND Hepatopulmonary syndrome (HPS) is a pulmonary complication of advanced liver disease with dyspnea as the predominant presenting symptom. The diagnosis of HPS can often be missed due to its nonspecific presentation and the presence of other comorbidities. CASE REPORT We present an interesting case of an obese 43-year-old man who presented with progressive, unexplained hypoxemia and shortness of breath in the absence of any symptoms or signs of chronic liver disease. After extensive cardiopulmonary investigations, he was diagnosed with severe HPS as a result of non-alcoholic steatohepatitis (NASH) leading to cirrhosis...
January 2, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/28035806/microfluidic-reactors-based-on-rechargeable-catalytic-porous-supports-heterogeneous-enzymatic-catalysis-via-reversible-host-guest-interactions
#20
Alberto Sanz de León, Nelson Vargas-Alfredo, Alberto Gallardo, Alfonso Fernández-Mayoralas, Agatha Bastida, Alexandra Muñoz-Bonilla, Juan Rodríguez-Hernández
We report on the fabrication of a microfluidic device in which the reservoir contains a porous surface with enzymatic catalytic activity provided by the reversible immobilization of horseradish peroxidase onto micrometer size pores. The porous functional reservoir was obtained by the Breath Figures approach by casting in a moist environment a solution containing a mixture of high molecular weight polystyrene (HPS) and a poly(styrene-co-cyclodextrin based styrene) (P(S-co-SCD)) statistical copolymer. The pores enriched in CD were employed to immobilize horseradish peroxidase (previously modified with adamantane) by host-guest interactions (HRP-Ada)...
February 1, 2017: ACS Applied Materials & Interfaces
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