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Arthur P DeMarzo
New guidelines on hypertension eliminated the classification of prehypertension and divided those blood pressure (BP) levels into elevated BP and stage 1 hypertension. For elevated BP, this study showed that cardiovascular (CV) abnormalities were prevalent in adults over 40 years of age with at least 2 CV risk factors. Detecting abnormalities of the CV system moves a patient from being at high risk to having earlystage cardiovascular disease (CVD) and supports a decision to treat. By redefining stage 1 and lowering the target BP, the new guidelines have set an ambitious goal for early intervention to prevent progression of CVD...
February 22, 2018: High Blood Pressure & Cardiovascular Prevention: the Official Journal of the Italian Society of Hypertension
Josária Ferraz Amaral, Diana de Medeiros Andrade Borsato, Isabelle Magalhães Guedes Freitas, Edgar Toschi-Dias, Daniel Godoy Martinez, Mateus Camaroti Laterza
BACKGROUND: Individuals with a family history of systemic arterial hypertension (FHSAH) and / or prehypertension have a higher risk of developing this pathology. OBJECTIVE: To evaluate the autonomic and vascular functions of prehypertensive patients with FHSAH. METHODS: Twenty-five young volunteers with FHSAH, 14 normotensive and 11 prehypertensive subjects were submitted to vascular function evaluation by forearm vascular conductance(VC) during resting and reactive hyperemia (Hokanson®) and cardiac and peripheral autonomic modulation, quantified, respectively, by spectral analysis of heart rate (ECG) and systolic blood pressure (SBP) (FinometerPRO®)...
February 19, 2018: Arquivos Brasileiros de Cardiologia
Sheri L Balsara, Joshua A Samuels, Joyce P Samuel, Cynthia S Bell
Fourth Report guidelines on pediatric blood pressure (BP) are not clear when defining hypertension in children as "an average systolic BP and/or diastolic BP ≥ 95th percentile for gender, age, and height on ≥ 3 occasions." We aimed to determine the prevalence of pediatric hypertension in a screening population based on two different guideline interpretations. Prevalence of hypertension among 2094 students at four Houston area schools was calculated based on the summation or sustained model definition from Fourth Report guidelines...
February 17, 2018: Journal of the American Society of Hypertension: JASH
Velusami Deepika, R Vijayakumar
BACKGROUND: Obesity and hypertension pose a big threat to public health. Targeting the prehypertension stage to evaluate the vascular damage due to obesity can help us to plan early interventions. STUDY DESIGN: A cross-sectional study. METHODS: This study as a part of the medical heath checkup program was conducted by the Medical College in Puducherry, India on all medical students of age group 18-25 years. Blood pressure (BP) recordings and body mass index (BMI) were classified into following four groups: Group1: Normotensives with normal BMI (n=109); Group 2: Normotensives with higher BMI (n=89); Group 3: Prehypertensive subjects with normal BMI (n=50); and Group 4: Prehypertensive subjects with higher BMI (n=99)...
December 27, 2017: Journal of Research in Health Sciences
John W M Yuen, Yoyo K Y Yan, Victor C W Wong, Wilson W S Tam, Ka-Wing So, Wai-Tong Chien
A cross-sectional study was designed to understand the impacts of "hikikomori" lifestyle on physical health. A total of 104 eligible hikikomori cases were recruited from the social services network of Hong Kong with a mean age of 19.02 ± 3.62 (ranged 13-31) year-old, and had completed the set of questionnaires and a series of anthropometric and physical health measurements. Despite SF36 score of 84.0 indicated good physical functioning in general, participants were lived sedentarily with high incidence of hypertension at 15...
February 11, 2018: International Journal of Environmental Research and Public Health
Lilia M Beltrán-Barrientos, Aarón F González-Córdova, Adrián Hernández-Mendoza, Eduardo H Torres-Inguanzo, Humberto Astiazarán-García, Julián Esparza-Romero, Belinda Vallejo-Cordoba
The blood pressure-lowering effect of fermented milk with Lactococcus lactis NRRL B-50571 was evaluated in a double-blind randomized controlled clinical trial with prehypertensive subjects. Participants were randomized into 2 groups (n = 18 each group): one group treated with fermented milk with Lactococcus lactis NRRL B-50571 and a control group treated with artificially acidified milk. Results revealed that during daily consumption of fermented milk for 5 wk, systolic [(116.55 ± 12.26 mmHg vs. 124.77 ± 11...
February 7, 2018: Journal of Dairy Science
Ryuichi Kawamoto, Daisuke Ninomiya, Kensuke Senzaki, Teru Kumagi
Background: Few data is available on the association between body mass index (BMI), serum uric acid (SUA) levels and blood pressure (BP) categories in the disease continuum, when efforts for its prevention may be applicable. Methods: We performed a cross-sectional study to examine the association between BMI, SUA and BP in a community-dwelling sample of Japanese men. Individuals not on antihypertensive and uric acid lowering medications, and aged 50 to 90 years [817men aged 66 ± 9 (mean ± standard deviation) years] were recruited for the survey during a community based annual medical check-up...
2018: Clinical Hypertension
Keisuke Okuno, Yoshiro Naito, Seiki Yasumura, Hisashi Sawada, Makiko Oboshi, Koichi Nishimura, Masanori Asakura, Masaharu Ishihara, Tohru Masuyama
Hypertension is a major public health problem leading to death. To reduce the morbidity and mortality in patients with hypertension, it is crucial to develop a novel strategy for prevention of hypertension. We have currently reported an attempt at dietary iron intake restriction as non-pharmacological treatment of hypertension in patients with hypertension. However, it remains fully unknown whether dietary iron restriction prevents the development of hypertension. We investigated the influence of dietary iron restriction on the development of hypertension in weanling pre-hypertensive model rats...
February 7, 2018: Heart and Vessels
Erin E Masterson, Annette L Fitzpatrick, Daniel A Enquobahrie, Lloyd A Mancl, Dan T A Eisenberg, Esther Conde, Philippe P Hujoel
OBJECTIVES: Bioarchaeological findings have linked defective enamel formation in preadulthood with adult mortality. We investigated how defective enamel formation in infancy and childhood is associated with risk factors for adult morbidity and mortality in adolescents. METHODS: This cohort study of 349 Amerindian adolescents (10-17 years of age) related extent of enamel defects on the central maxillary incisors (none, less than 1/3, 1/3 to 2/3, more than 2/3) to adolescent anthropometrics (height, weight) and biomarkers (hemoglobin, glycated hemoglobin, white blood cell count, and blood pressure)...
February 5, 2018: American Journal of Human Biology: the Official Journal of the Human Biology Council
Abimbola Allison, Aliyar Fouladkhah
Although vital for maintaining health when consumed in moderation, various epidemiological studies in recent years have shown a strong association between excess dietary sodium with an array of health complications. These associations are robust and clinically significant for development of hypertension and prehypertension, two of the leading causes of preventable mortality worldwide, in adults with a high-sodium diet. Data from developed nations and transition economies show worldwide sodium intake of higher than recommended amounts in various nations...
February 1, 2018: Foods (Basel, Switzerland)
Ju Young Jung, Chang-Mo Oh, Jae-Hong Ryoo, Joong-Myung Choi, Young-Jun Choi, Woo Taek Ham, Sung Keun Park
BACKGROUND: It has been reported that elevated blood pressure (BP) was significantly associated with the increased risk for type 2 diabetes mellitus (T2DM). However, there is still limited information about the influence of BP on the risk for T2DM across the level of glycated hemoglobin (HbA1c). METHOD: In a cohort of the Korean Genome and Epidemiology Study (KoGES), 2830 non-diabetic Korean adults with prediabetes defined by HbA1c level of 5.7-6.4% were followed-up for 10 years...
January 29, 2018: Endocrine
Zoran Milanović, Saša Pantelić, Nedim Čović, Goran Sporiš, Magni Mohr, Peter Krustrup
BACKGROUND: A previous meta-analysis showed that maximal oxygen uptake increased by 3.51 mL/kg/min (95% CI 3.07 to 4.15) during a recreational football programme of 3-6 months in comparison with continuous moderate-intensity running, strength training or a passive control group. In addition, narrative reviews have demonstrated beneficial effects of recreational football on physical fitness and health status. OBJECTIVE: The purpose of this systematic review and meta-analysis was to evaluate the magnitude of effects of recreational football on blood pressure, body composition, lipid profile and muscular fitness with reference to age, gender and health status...
January 25, 2018: British Journal of Sports Medicine
Mirjana Djeric, Branislava Ilincic, Velibor Cabarkapa, Isidora Radosavkic, Aleksandra Trifu, Masa Todorovic
No abstract text is available yet for this article.
August 2017: Atherosclerosis
Sofiane Rahali, Yuan Li, Madhu B Anand-Srivastava
Earlier studies have shown the implication of growth factor receptor activation in angiotensin II (Ang II)-induced hyperproliferation of aortic VSMC as well as in hyperproliferation of VSMC from spontaneously hypertensive rats (SHR). We previously showed that NPR-C specific agonist C-ANP4-23 attenuates the hyperproliferation of VSMC from SHR through the inhibition of MAP kinase, Giα protein signaling and overexpression of cell cycle proteins. The aim of the present study was to investigate if C-ANP4-23- mediated attenuation of hyperproliferation of VSMC from SHR also involves growth factor receptor activation and upstream signaling molecules...
2018: PloS One
Adegbenro Omotuyi John Fakoya, David Adeiza Otohinoyi, Terrence Marcelle, Joshua Yusuf
BACKGROUND: Several speculations have linked the size of the fist to be equal to the size of the heart. However, the substantial scientific report still lacks to support this theory. AIM: This study aims to provide the validity of the fist-heart assumption by correlating the palm and heart diameters while benchmarking it as a reference tool for determining the normal heart size. MATERIALS AND METHOD: Volunteers from the public were recruited during a health fair organised by the school...
December 15, 2017: Open Access Macedonian Journal of Medical Sciences
Dhanush Haspula, Michelle A Clark
Essential hypertension is a multifactorial disorder with a strong genetic predisposition. Although anti-hypertensive medications have drastically reduced cardiovascular diseases mortality and morbidity rates, a significant percentage of hypertensive individuals currently on anti-hypertensive therapy, remain hypertensive. In spite of the emergence of transgenic animals and sophisticated tools to study the pathophysiology of hypertension, unraveling the causal mechanisms remains a challenge. Research on borderline hypertensive humans and/or prehypertensive rat models revealed an elevation in centrally-mediated sympathetic activity and a heightened neuroinflammatory state...
January 12, 2018: Autonomic Neuroscience: Basic & Clinical
A Zemančíková, J Török
The aim of this study was to investigate the effect of high fructose intake associated with moderate increase in adiposity on rat arterial adrenergic responses and their modulation by perivascular adipose tissue (PVAT). After eight-week-lasting substitution of drinking water with 10 % fructose solution in adult normotensive Wistar-Kyoto rats (WKY) and spontaneously hypertensive rats (SHR), their systolic blood pressure, plasma triglycerides, and relative liver weight were elevated when compared to their respective control groups...
December 30, 2017: Physiological Research
Cheryl Robbins, Sheree L Boulet, Isabel Morgan, Denise V D'Angelo, Lauren B Zapata, Brian Morrow, Andrea Sharma, Charlan D Kroelinger
PROBLEM/CONDITION: Preconception health is a broad term that encompasses the overall health of nonpregnant women during their reproductive years (defined here as aged 18-44 years). Improvement of both birth outcomes and the woman's health occurs when preconception health is optimized. Improving preconception health before and between pregnancies is critical for reducing maternal and infant mortality and pregnancy-related complications. The National Preconception Health and Health Care Initiative's Surveillance and Research work group suggests ten prioritized indicators that states can use to monitor programs or activities for improving the preconception health status of women of reproductive age...
January 19, 2018: MMWR. Surveillance Summaries: Morbidity and Mortality Weekly Report. Surveillance Summaries
T N Anand, M Shaffi, M Pillai A, A Lathika Rajendrakumar, L S Sreemathy, K Rajasekharan Nayar, J Lordson, M Abraham, P Rajeev, A Marthanda Pillai, A Kumar, C Grace A, J Jacob
No abstract text is available yet for this article.
January 12, 2018: Public Health
Vasilis Tsimihodimos, Clicerio Gonzalez-Villalpando, James B Meigs, Ele Ferrannini
Type 2 diabetes mellitus and hypertension overlap in the population. In many subjects, development of diabetes mellitus is characterized by a relatively rapid increase in plasma glucose values. Whether a similar phenomenon occurs during the development of hypertension is not known. We analyzed the pattern of blood pressure (BP) changes during the development of hypertension in patients with or without diabetes mellitus using data from the MCDS (Mexico City Diabetes Study; a population-based study of diabetes mellitus in Hispanic whites) and in the FOS (Framingham Offspring Study, a community-based study in non-Hispanic whites) during a 7-year follow-up...
March 2018: Hypertension
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