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Prehypertension

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https://www.readbyqxmd.com/read/28231078/effects-of-aerobic-exercise-training-on-ace-and-adrb2-gene-expression-plasma-angiotensin-ii-level-and-flow-mediated-dilation-a-study-on-obese-postmenopausal-women-with-prehypertension
#1
Noushin Azadpour, Bakhtyar Tartibian, Şükran Nazan Koşar
OBJECTIVE: The purpose of this study is to determine the effect of 10 weeks of moderate-intensity aerobic exercise training (MIET) on blood pressure (BP), angiotensin-converting enzyme (ACE) and β2-adrenergic receptor (ADRB2) gene expression in leukocytes, plasma angiotensin II (Ang II), and flow-mediated dilation (FMD) in obese postmenopausal women (PMW) with prehypertension. METHODS: Twenty-four obese prehypertensive PMW (aged 50-70 y; body mass index ≥30 kg/m) randomly assigned to control (n = 12) and exercise (n = 12) groups...
March 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28230200/prevalence-of-prehypertension-and-left-ventricular-hypertrophy
#2
Jun-Ichi Oyama, Koichi Node
No abstract text is available yet for this article.
February 23, 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/28223474/can-pediatric-hypertension-criteria-be-simplified-a-prediction-analysis-of-subclinical-cardiovascular-outcomes-from-the-bogalusa-heart-study
#3
Bo Xi, Tao Zhang, Shengxu Li, Emily Harville, Lydia Bazzano, Jiang He, Wei Chen
Prehypertension and hypertension in childhood are defined by sex-, age-, and height-specific 90th (or ≥120/80 mm Hg) and 95th percentiles of blood pressure, respectively, by the 2004 Fourth Report. However, these cutoffs are complex and cumbersome for use. This study assessed the performance of a simplified blood pressure definition to predict adult hypertension and subclinical cardiovascular disease. The cohort consisted of 1225 adults (530 men; aged 26.3-47.7 years) from the Bogalusa Heart Study with 27...
February 21, 2017: Hypertension
https://www.readbyqxmd.com/read/28207613/vagal-regulation-of-cardiac-function-in-early-childhood-and-cardiovascular-risk-in-adolescence
#4
Meghan J Gangel, Lilly Shanahan, Jacek Kolacz, James A Janssen, Ashley Brown, Susan D Calkins, Susan P Keane, Laurie Wideman
OBJECTIVE: Poor behavioral self-regulation in the first two decades of life has been identified as an important precursor of disease risk in adulthood. However, physiological regulation has not been well-studied as a disease risk factor before adulthood. We tested whether physiological regulation at age two, in the form of vagal regulation of cardiac function (indexed by RSA change), would predict three indicators of cardiovascular risk at age 16 (diastolic and systolic blood pressure and body mass index)...
February 15, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/28190873/the-role-of-uric-acid-in-hypertension-of-adolescents-prehypertension-and-salt-sensitivity-of-blood-pressure
#5
Yang Wang, Jia-Wen Hu, Yong-Bo Lv, Chao Chu, Ke-Ke Wang, Wen-Ling Zheng, Yu-Meng Cao, Zu-Yi Yuan, Jian-Jun Mu
Uric acid is the end product of purine metabolism. Metabolic disorders of uric acid are associated with many disease states. Substantial evidence suggests the possible role of uric acid as a mediator of high blood pressure. Elevated uric acid is closely associated with new onset essential hypertension in adolescents and prehypertension; and urate-lowering agents can significantly improve these early stages of hypertension. Uric acid also influences salt sensitivity of blood pressure through two phases. Local renin-angiotensin-aldosterone system activation initiates renal damage, arteriolopathy, and endothelium dysfunction, which is followed by the dysregulation of sodium homeostasis, thereby leading to increased salt sensitivity...
February 13, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28186098/postnatal-height-and-adiposity-gain-childhood-blood-pressure-and-prehypertension-risk-in-an-asian-birth-cohort
#6
I M Aris, J Y Bernard, L-W Chen, M T Tint, W Y Lim, S E Soh, S-M Saw, Lp-C Shek, K M Godfrey, P D Gluckman, Y-S Chong, F Yap, M S Kramer, Y S Lee
OBJECTIVE: There have been hypotheses that early life adiposity gain may influence blood pressure (BP) later in life. We examined associations between timing of height, body mass index (BMI) and adiposity gains in early life with BP at 48 months in an Asian pregnancy-birth cohort. METHODS: In 719 children, velocities for height, BMI and abdominal circumference (AC) were calculated at five intervals [0-3, 3-12, 12-24, 24-36 and 36-48 months]. Triceps (TS) and subscapular skinfold (SS) velocities were calculated between 0-18, 18-36 and 36-48 months...
February 10, 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/28169886/prehypertension-among-2-19-million-adolescents-and-future-risk-for-end-stage-renal-disease
#7
Adi Leiba, Gilad Twig, Asaf Vivante, Karl Skorecki, Eliezer Golan, Estela Derazne, Dorit Tzur, Ehud Grossman, Rita Dichtiar, Jeremy D Kark, Tamar Shohat
OBJECTIVE: Persistent hypertension in adulthood is a leading cause of end-stage renal disease (ESRD). Whether lower blood pressure (BP) values, in the range of prehypertension, are also associated with future occurrence of ESRD is unclear. Even less clear is the potential risk of early prehypertension appearing in adolescence. To address this question, we examined whether BP measurements in the prehypertensive range at age 16-19 years predict adult ESRD. METHODS: Medical data on 2194 635 16-19-year-old adolescents examined for medical fitness prior to military service from 1977 to 2013 were linked to the Israeli ESRD registry in this nationwide population-based cohort study...
February 6, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28169882/greater-visceral-abdominal-fat-is-associated-with-a-lower-probability-of-conversion-of-prehypertension-to-normotension
#8
You-Cheol Hwang, Wilfred Y Fujimoto, Steven E Kahn, Donna L Leonetti, Edward J Boyko
OBJECTIVE: Prehypertension is associated with increased risk for incident hypertension. However, little is known about how frequently prehypertension converts to normotension, and which variables predict this conversion. METHODS: We identified 186 Japanese Americans with prehypertension (110 men, 76 women) aged 34-75 years (mean age of 52.3 years) who were followed at 5 and 10 years after enrollment. Blood pressure was measured with a mercury sphygmomanometer and average blood pressure was calculated...
February 6, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28161159/early-treatment-with-losartan-effectively-ameliorates-hypertension-and-improves-vascular-remodeling-and-function-in-a-prehypertensive-rat-model
#9
De-Hua He, Jin-Xiu Lin, Liang-Min Zhang, Chang-Sheng Xu, Qiang Xie
AIMS: Pharmacological treatment of prehypertension may ameliorate hypertension and improve vascular structure and function. This study investigated 1) whether early treatment with either losartan or amlodipine at the onset of prehypertension can prevent hypertension and 2) whether losartan and amlodipine equally improve vascular remodeling and function in a rat model of hypertension. MATERIALS AND METHODS: Stroke-prone spontaneously hypertensive (SHRSP) rats were administered losartan, amlodipine or saline for 6 or 16weeks at the onset of prehypertension...
February 1, 2017: Life Sciences
https://www.readbyqxmd.com/read/28161097/prevalence-of-hypertension-and-hypertension-phenotypes-by-age-and-gender-among-schoolchildren-in-greece-the-healthy-growth-study
#10
Kalliopi Karatzi, Athanase D Protogerou, George Moschonis, Christiana Tsirimiagou, Odysseas Androutsos, George P Chrousos, Christos Lionis, Yannis Manios
BACKGROUND AND AIMS: Childhood hypertension is a constantly increasing health problem. Data regarding its prevalence and particularly the prevalence of its phenotypes in the Greek population are limited; therefore, the aim of the study was to determine them in a large sample of Greek children. METHODS: A sample of 2655 schoolchildren (9-13 years) participated in the Healthy Growth Study, i.e. a cross-sectional epidemiologic study conducted in 77 primary schools in four large regions in Greece...
January 21, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28142077/associations-among-oxidative-stress-lp-pla2-activity-and-arterial-stiffness-according-to-blood-pressure-status-at-a-3-5-year-follow-up-in-subjects-with-prehypertension
#11
Minkyung Kim, Hye Jin Yoo, Minjoo Kim, Hyeon Yeong Ahn, Jiyeong Park, Sang-Hyun Lee, Jong Ho Lee
BACKGROUND AND AIMS: We aimed to determine changes in oxidative stress, lipoprotein-associated phospholipase A2 (Lp-PLA2) activity and arterial stiffness in subjects with persistent prehypertensive symptoms during a 3.5-year follow-up period. METHODS: We divided 254 subjects with prehypertension according to their blood pressure (BP) status at 3.5 years of follow-up into three groups: reversed normotensive, persistent prehypertensive and developed hypertensive group...
January 13, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28141860/prevalence-of-high-blood-pressure-and-association-with-obesity-in-spanish-schoolchildren-aged-4-6-years-old
#12
Noelia Martín-Espinosa, Ana Díez-Fernández, Mairena Sánchez-López, Irene Rivero-Merino, Lidia Lucas-De La Cruz, Montserrat Solera-Martínez, Vicente Martínez-Vizcaíno
BACKGROUND: The prevalence of high blood pressure in children is increasing worldwide, largely, but not entirely, driven by the concurrent childhood obesity epidemic. The aims of this study were to examine the prevalence of prehypertension and hypertension in 4-to-6-year-old Spanish schoolchildren, and to evaluate the association between different blood pressure (BP) components with different adiposity indicators. METHODS: Cross-sectional study including a sample of 1...
2017: PloS One
https://www.readbyqxmd.com/read/28135198/progression-from-prehypertension-to-hypertension-and-risk-of-cardiovascular-disease
#13
Yukiko Ishikawa, Joji Ishikawa, Shizukiyo Ishikawa, Kazuomi Kario, Eiji Kajii
BACKGROUND: Subjects with prehypertension (pre-HT; 120/80 to 139/89 mm Hg) have an increased risk of cardiovascular disease (CVD); however, whether the risk of pre-HT can be seen at the pre-HT status or only after progression to a hypertensive (HT; ≥140/90 mm Hg) state during the follow-up period is unknown. METHODS: The Jichi Medical Cohort study enrolled 12,490 subjects recruited from a Japanese general population. Of those, 2227 subjects whose BP data at baseline and at the middle of follow-up and tracking of CVD events were available (median follow-up period: 11...
January 2017: Journal of Epidemiology
https://www.readbyqxmd.com/read/28125521/reproducibility-of-24-h-ambulatory-blood-pressure-and-measures-of-autonomic-function
#14
Niamh M Morrin, Mark R Stone, Keiran J Henderson
Determining the number of familiarization sessions required for accurate recordings of ambulatory blood pressure monitoring and autonomic function is a prerequisite for the appropriate design of intervention studies. The benefit of familiarization trials remains largely unexplored. The objective of the current investigation was to assess the reproducibility of 24-h ambulatory blood pressure, 24-h heart rate variability (HRV) and resting measurements of HRV and blood pressure variability (BPV). Eleven prehypertensive and hypertensive adults participated...
January 25, 2017: Blood Pressure Monitoring
https://www.readbyqxmd.com/read/28123182/the-influence-of-prehypertension-controlled-and-uncontrolled-hypertension-on-left-ventricular-diastolic-function-and-structure-in-the-general-korean-population
#15
Ju Young Jung, Sung Keun Park, Chang-Mo Oh, Jeong Gyu Kang, Joong-Myung Choi, Jae-Hong Ryoo, Jae-Hon Lee
Although hypertension is a clear risk factor for cardiovascular disease, how prehypertension and controlled hypertension influence left ventricular (LV) diastolic function and structure remain to be elucidated. Thus, this study was intended to investigate the link between LV diastolic dysfunction and structural changes in different categories of hypertension. A cohort of 52 111 Korean adults receiving echocardiograms was enrolled. The study population was stratified into five groups according to the following categories of hypertension and blood pressure (BP): normotensive (<120/80 mm Hg), prehypertensive (120-139/80-89 mm Hg), controlled hypertensive (<140/90 mm Hg), newly recognized hypertensive and uncontrolled hypertensive (⩾140/90 mm Hg)...
January 26, 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/28115703/complementary-roles-of-gasotransmitters-co-and-h2s-in-sleep-apnea
#16
Ying-Jie Peng, Xiuli Zhang, Anna Gridina, Irina Chupikova, David L McCormick, Robert J Thomas, Thomas E Scammell, Gene Kim, Chirag Vasavda, Jayasri Nanduri, Ganesh K Kumar, Gregg L Semenza, Solomon H Snyder, Nanduri R Prabhakar
Sleep apnea, which is the periodic cessation of breathing during sleep, is a major health problem affecting over 10 million people in the United States and is associated with several sequelae, including hypertension and stroke. Clinical studies suggest that abnormal carotid body (CB) activity may be a driver of sleep apnea. Because gaseous molecules are important determinants of CB activity, aberrations in their signaling could lead to sleep apnea. Here, we report that mice deficient in heme oxygenase-2 (HO-2), which generates the gaseous molecule carbon monoxide (CO), exhibit sleep apnea characterized by high apnea and hypopnea indices during rapid eye movement (REM) sleep...
February 7, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28115515/does-extremely-low-birth-weight-predispose-to-low-renin-hypertension
#17
Anke Raaijmakers, Zhen-Yu Zhang, Jolien Claessens, Nicholas Cauwenberghs, Theun Pieter van Tienoven, Fang-Fei Wei, Lotte Jacobs, Elena Levtchenko, Steven Pauwels, Tatiana Kuznetsova, Karel Allegaert, Jan A Staessen
: Low birth weight and prematurity are risk factors for hypertension in adulthood. Few studies in preterm or full-term born children reported on plasma renin activity (PRA). We tested the hypothesis that renin might modulate the incidence of hypertension associated with prematurity. We enrolled 93 prematurely born children with birth weight <1000 g and 87 healthy controls born at term, who were all examined at ≈11 years. Renal length and glomerular filtration rate derived from serum cystatin C were 0...
March 2017: Hypertension
https://www.readbyqxmd.com/read/28106664/ethnic-differences-regarding-arterial-stiffness-of-6-8-year-old-black-and-white-boys
#18
Gontse G Mokwatsi, Aletta E Schutte, Ruan Kruger
OBJECTIVES: Vascular deterioration is suggested to occur earlier in black than white populations, thereby increasing their risk for developing hypertension. To establish whether this is the case, we compared different estimates of arterial stiffness in black and white children and investigated the links with body composition and advanced glycation end products (AGEs) as potential contributors. METHODS: We included 40 black and 41 white boys (aged 6-8 years) from similar schools and measured arterial stiffness [pulse wave velocity (PWV) in different arterial sections, systemic arterial compliance and carotid stiffness estimates], anthropometry as well as urinary pentosidine as a marker of AGEs...
January 18, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28100465/prevalence-of-masked-hypertension-among-us-adults-with-nonelevated-clinic-blood-pressure
#19
Y Claire Wang, Daichi Shimbo, Paul Muntner, Andrew E Moran, Lawrence R Krakoff, Joseph E Schwartz
Masked hypertension (MHT), defined as nonelevated blood pressure (BP) in the clinic setting and elevated BP assessed by ambulatory monitoring, is associated with increased risk of target organ damage, cardiovascular disease, and mortality. Currently, no estimate of MHT prevalence exists for the general US population. After pooling data from the Masked Hypertension Study (n = 811), a cross-sectional clinical investigation of systematic differences between clinic BP and ambulatory BP (ABP) in a community sample of employed adults in the New York City metropolitan area (2005-2012), and the National Health and Nutrition Examination Survey (NHANES; 2005-2010; n = 9,316), an ongoing nationally representative US survey, we used multiple imputation to impute ABP-defined hypertension status for NHANES participants and estimate MHT prevalence among the 139 million US adults with nonelevated clinic BP, no history of overt cardiovascular disease, and no use of antihypertensive medication...
January 18, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28095471/prevalence-and-risk-factors-of-prehypertension-and-hypertension-in-southern-china
#20
Lihua Hu, Xiao Huang, Chunjiao You, Juxiang Li, Kui Hong, Ping Li, Yanqing Wu, Qinhua Wu, Huihui Bao, Xiaoshu Cheng
BACKGROUND: This study aimed to describe the prevalence and risk factors of prehypertension and hypertension in Jiangxi Province, China. Individuals with prehypertension frequently progress into hypertension and are at high risk of developing cardiovascular disease and stroke. METHODS: A cross-sectional survey of 15,296 participants (15 years or older) was conducted in Jiangxi Province, China, in 2013, using questionnaire forms and physical measurements. RESULTS: The prevalence of prehypertension and hypertension was 32...
2017: PloS One
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