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https://www.readbyqxmd.com/read/28334569/incidence-and-risk-factors-of-caesarean-section-in-preterm-breech-births-a-population-based-cohort-study
#1
Elsa Lorthe, Mathilde Quere, Loïc Sentilhes, Pierre Delorme, Gilles Kayem
OBJECTIVES: To describe the incidence of breech presentation at 22-34 weeks' gestation, estimate the incidence of cesarean section delivery by cause of prematurity, and assess the factors associated with caesarean delivery in preterm breech births with preterm labor or preterm premature rupture of membranes. STUDY DESIGN: EPIPAGE 2 is a French national prospective population-based cohort study of preterm births that occurred in 546 maternity units in 2011. We estimated the overall incidence of breech presentation and the incidence of cesarean delivery by cause of prematurity...
March 10, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28316039/public-health-data-in-action-an-analysis-of-using-louisiana-vital-statistics-for-quality-improvement-and-payment-reform
#2
Valery A Danilack, Rebekah E Gee, Danielle P Berthelot, Rebecca Gurvich, Janet H Muri
Introduction In 2012, the Louisiana (LA) Department of Health and Hospitals revised the LA birth certificate to include medical reasons for births before 39 completed weeks' gestation. We compared the completeness and validity of these data with hospital discharge records. Methods For births occurring 4/1/2012-9/30/2012 at Woman's Hospital of Baton Rouge, we linked maternal delivery and newborn birth data collected through the National Perinatal Information Center with LA birth certificates. Among early term births (37-38 completed weeks' gestation), we quantified the reasons for early delivery listed on the birth certificate and compared them with ICD-9-CM codes from Woman's discharge data...
March 18, 2017: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/28290835/-the-course-of-pregnancy-in-women-with-arterial-hypertension
#3
Ya V Brytkova, R I Stryuk
We included in this study 69 women with hypertension in the II trimester of pregnancy, of whom 52 (75%) had normal weight gain during the period of gestation, and 17 (25%) had abnormal weight gain. Comprehensive clinical and instrumental examination included calculation of body mass index before and during gestation, 24-hour ambulatory blood pressure (BP) monitoring, assessment of activity of sympathetic-adrenal system by quantification of -adrenoreception of erythrocytes cell membranes. Women with excessive weight gain during gestation were older, more often had increased body weight before pregnancy...
January 2017: Kardiologiia
https://www.readbyqxmd.com/read/28282773/association-of-periodontitis-with-preterm-birth-and-low-birth-weight-a-comprehensive-review
#4
Alberto Puertas, Antonio Magan-Fernandez, Vanessa Blanc, Laura Revelles, Francisco O'Valle, Elena Pozo, Ruben León, Francisco Mesa
It is estimated that six million perinatal deaths occur every year worldwide, with premature birth being the main cause. Scientific evidence has shown that there is an association between periodontal health during pregnancy and adverse outcomes of labor, although interventional studies based on the treatment of periodontitis have failed to document an impact on reducing the incidence of preterm birth (PB) or low birth weight (LBW). Two pathogenic mechanisms have been proposed to explain this association. The direct pathway is based on the presence of gram-negative anaerobic bacteremia originating in the gingival biofilm, whereas the indirect pathway involves the production of pro-inflammatory markers which enter the bloodstream from the gingival submucosa...
February 28, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28278303/clinical-significance-of-histologic-chorioamnionitis-with-a-negative-amniotic-fluid-culture-in-patients-with-preterm-labor-and-premature-membrane-rupture
#5
Jeong Woo Park, Kyo Hoon Park, Eun Young Jung
OBJECTIVE: To evaluate the effect of histological chorioamnionitis (HCA) with a negative amniotic fluid (AF) culture on adverse pregnancy and neonatal outcomes and inflammatory status in the AF compartment in women with preterm labor or preterm premature rupture of membranes (PPROM). METHODS: This is a retrospective cohort study of 153 women diagnosed as having a preterm labor or PPROM (20-34 weeks) who delivered singleton gestations within 48 hours of amniocentesis...
2017: PloS One
https://www.readbyqxmd.com/read/28267444/a-multicenter-prospective-study-of-neonatal-outcomes-at-less-than-32-weeks-associated-with-indications-for-maternal-admission-and-delivery
#6
Thomas J Garite, C Andrew Combs, Kimberly Maurel, Anita Das, Kevin Huls, Richard Porreco, Dale Reisner, George Lu, Melissa Bush, Bruce Morris, April Bleich
BACKGROUND: Counseling for patients with impending premature delivery has been traditionally based primarily on the projected gestational age at delivery. There are limited data regarding how the indications for the preterm birth affect the neonatal outcome and whether this issue should be taken into account in decisions regarding management and patient counseling. OBJECTIVE: We performed a prospective study of pregnancies resulting in premature delivery at less than 32 weeks to determine the influence of both the Indications for Admission and their associated Indications for Delivery on neonatal mortality and complications of prematurity...
March 3, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28258032/morbidity-and-mortality-trends-in-very-very-low-birth-weight-premature-infants-in-light-of-recent-changes-in-obstetric-care
#7
Péter Varga, Botond Berecz, Ákos Gasparics, Zsófia Dombi, Zsuzsa Varga, Judit Jeager, Zsófia Magyar, János Rigó, József Gábor Joó, László Kornya
OBJECTIVE: In this study, we describe trends in morbidity and mortality of preterm infants with less than 500mg birth weight in the changing landscape of obstetric and neonatal care. STUDY DESIGN: During a ten year study period between 2006 and 2016 we assessed outcome data for all neonates with less than 500mg birth weight born at our Neonatal Intensive Care Unit. We divided study subjects into two groups based on whether their birth date fell in the first half (2006-2010; n=39) versus the second half (2011-2015; n=27) of the study period comparing clinical outcomes in the two groups...
January 23, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28216926/urological-disorders-and-pregnancy-an-overall-experience
#8
Debasmita Mandal, Mriganka Mouli Saha, Dillip Kumar Pal
AIM: Pregnancy is an anatomical and physiological altered state and the presence of various urological problems not only aggravates the disease itself, but also results in unfavourable pregnancy outcome. Aim is to highlight obstetric outcome in pregnant women with urological problems. MATERIALS AND METHODS: Longitudinal prospective cohort study conducted in tertiary care hospital, IPGME and R, Kolkata from Jan 2011 to Dec 2012. All pregnant women with urological problems were included as subjects...
January 2017: Urology Annals
https://www.readbyqxmd.com/read/28210714/fetal-cholelithiasis-antenatal-diagnosis-and-neonatal-follow-up-in-a-case-of-twin-pregnancy-a-case-report-and-review-of-the-literature
#9
Yannick Hurni, Francesco Vigo, Begoña Lipp von Wattenwyl, Nicole Ochsenbein, Claudia Canonica
Fetal cholelithiasis is a rare finding during a third-trimester ultrasound with an average incidence rate of 0.07-1.15%. We report a case of fetal cholelithiasis in twins, observed in a patient with monochorionic diamniotic twin pregnancy hospitalized at our unit for signs of premature labor. We present the outcome of the 2 neonates with a clinical and sonographic follow-up. In addition, we offer a comprehensive review of the literature available to date.
February 2017: Ultrasound International Open
https://www.readbyqxmd.com/read/28209491/the-preterm-cervix-reveals-a-transcriptomic-signature-in-the-presence-of-premature-prelabor-rupture-of-membranes
#10
Sofia Makieva, Aurelija Dubicke, Sara F Rinaldi, Emma Fransson, Gunvor Ekman-Ordeberg, Jane E Norman
BACKGROUND: Premature prelabor rupture of fetal membranes accounts for 30% of all premature births and is associated with detrimental long-term infant outcomes. Premature cervical remodeling, facilitated by matrix metalloproteinases, may trigger rupture at the zone of the fetal membranes overlying the cervix. The similarities and differences underlying cervical remodeling in premature prelabor rupture of fetal membranes and spontaneous preterm labor with intact membranes are unexplored...
February 15, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28202378/neonatology-oxidative-status-in-preterm-infants-with-premature-preterm-rupture-of-membranes-and-fetal-inflammatuar-response-syndrome
#11
Elif Özalkaya, Güner Karatekin, Sevilay Topçuoğlu, Hande Özgün Karatepe, Taner Hafızoğlu, Pervin Baran, Fahri Ovalı
BACKGROUND: The aim of this study, to determine an index of oxidative stress index in preterm infants less than 34 weeks gestational age with premature preterm rupture of membrane (PPROM) and fetal inflammatory response syndrome (FIRS). METHODS: This study was designed as a prospective study. Fifty-one premature infants less than 35 weeks of gestational age were included in the study. The umbilical cord blood concentrations of IL-6, TAC (total antioxidant capacity) and PON-1 (paraoxonase-1) levels and TOS (total oxidative stress) were studied...
January 17, 2017: Pediatrics and Neonatology
https://www.readbyqxmd.com/read/28188592/redirecting-reproductive-immunology-research-toward-pregnancy-as-a-period-of-temporary-immune-tolerance
#12
Norbert Gleicher, Vitaly A Kushnir, David H Barad
Referring to two recent publications, we here propose that clinical reproductive immunology has for decades stagnated because reproductive medicine, including assisted reproduction (AR), has failed to accept embryo implantation as an immune system-driven process, dependent on establishment of maternal tolerance toward the implanting fetal semi-allograft (and complete allograft in cases of oocyte donation). Pregnancy represents a biologically unique period of temporary (to the period of gestation restricted) tolerance, otherwise only known in association with parasitic infections...
February 10, 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/28178310/diversity-and-composition-of-vaginal-microbiota-of-pregnant-women-at-risk-for-transmitting-group-b-streptococcus-treated-with-intrapartum-penicillin
#13
Luiz Fernando Wurdig Roesch, Rita C Silveira, Andréa L Corso, Priscila Thiago Dobbler, Volker Mai, Bruna S Rojas, Álvaro M Laureano, Renato S Procianoy
BACKGROUND: Administering intravenous antibiotics during labor to women at risk for transmitting Group B Streptococcus (GBS) can prevent infections in newborns. However, the impact of intrapartum antibiotic prophylaxis on mothers' microbial community composition is largely unknown. We compared vaginal microbial composition in pregnant women experiencing preterm birth at ≤ 32 weeks gestation that received intrapartum antibiotic prophylaxis with that in controls. METHODS: Microbiota in vaginal swabs collected shortly before delivery from GBS positive women that received penicillin intravenously during labor or after premature rupture of membranes was compared to controls...
2017: PloS One
https://www.readbyqxmd.com/read/28176511/prevalence-of-illicit-drug-use-at-the-end-of-pregnancy-a-cross-sectional-study-at-the-time-of-birth
#14
Amadeu Roca Comas, Joan S Vila Domènech, Joana Massa Solé, Patricia Timoneda Paz, Mar Peñas Boira, Francisco J Herrero Espinet, Josep Sánchez Jiménez, Anna Ballester Martínez
BACKGROUND: Drug use during pregnancy is associated with adverse perinatal outcomes. This study was conducted to assess the prevalence of consumption of drugs of abuse in pregnant women at the end of gestation. METHODS: Cross-sectional study of all consecutive pregnant women in labor admitted to a regional hospital in Calella (Barcelona, Spain) in labor over one year period (2014- 2015). Women who gave written consent to take part in the study provided a urine sample on admission and completed a questionnaire with toxic habits-related questions...
February 7, 2017: Minerva Pediatrica
https://www.readbyqxmd.com/read/28170341/the-effects-of-antenatal-glucocorticoid-exposure-on-fetal-and-neonatal-skin-maturation
#15
Deanne August, Yogavijayan Kandasamy
AIMS: The use of antenatal glucocorticoids in women with preterm labor has dramatically improved outcomes for premature infants. The most commonly used antenatal glucocorticoids are betamethasone and dexamethasone. Glucocorticoids accelerate fetal lung growth by several mechanisms, including the maturation of type II pneumocytes enabling surfactant production. Furthermore, the lipids in the lung share similarity with those in the skin. Therefore, antenatal administration of glucocorticoids may have effects on the structure and function of the developing epidermal barrier in fetuses and neonates...
February 7, 2017: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/28168779/impact-of-risk-factors-for-perinatal-events-in-japan-introduction-of-a-newly-created-perinatal-event-score
#16
Yoshio Matsuda, Kemal Sasaki, Kaoru Kakinuma, Toshiyuki Kakinuma, Miki Tagawa, Ken Imai, Hiroaki Nonaka, Michitaka Ohwada, Shoji Satoh
AIM: A cohort study was performed to clarify the influence of risk factors on perinatal events (obstetric complications and/or perinatal deaths). METHODS: This cohort study reviewed 395 785 births from 2011 to 2013. Women with singleton pregnancies delivered after 22 weeks of gestation were included. The OR were determined on multivariate analysis. The perinatal event score (PES) for risk factors, which is the product of the OR of risk factors for obstetric complications, OR of risk factors for perinatal death, and OR of obstetric complications for perinatal death, was introduced to clarify the impact of each risk combination...
February 7, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/28166960/effects-of-zd7288-a-hyperpolarization-activated-cyclic-nucleotide-gated-hcn-channel-blocker-on-term-pregnant-rat-uterine-contractility-in%C3%A2-vitro
#17
Mohammed Alotaibi, Karima Kahlat, Taoufik Nedjadi, Laiche Djouhri
The uterus is a myogenic organ that is able to produce discrete spontaneous action potentials and contractions without any stimuli. Myometrial excitability is governed by ion channels including Ca(+2) and K(+) channels, but whether or not other channels such as hyperpolarization-activated cyclic nucleotide-gated (HCN) channels, which play an important role in regulating cellular excitability, are also involved has not been reported in uterine smooth muscles. The aim of the present study was to examine whether blocking HCN channels with a specific blocker ZD7288 would modulate the uterine contractility in a rat model...
March 1, 2017: Theriogenology
https://www.readbyqxmd.com/read/28165444/correlation-between-cervical-infection-and-preterm-labor
#18
Larisa Mešić Ðogić, Nenad Lučić, Dragana Mićić, Feđa Omeragić, Enes Hodžić, Seid Fazlagić, Refka Kovač, Nevenka Pavlović
Aim To investigate a correlation between cervical canal infection and imminent preterm labor and to identify most frequent pathogens. Methods A prospective study was conducted in obstetrics/gynecology departments of Health Center and the University Clinical Center Tuzla, and General Hospital Tešanj (Bosnia and Herzegovina, B&H) between October 2013 and May 2014. An examined group included 50 healthy pregnant women with singleton pregnancy of the gestation age between the 28th and 37th week, with cervical changes that are related to imminent preterm labor...
February 1, 2017: Medicinski Glasnik
https://www.readbyqxmd.com/read/28143536/the-impact-of-resilience-on-psychological-outcomes-in-women-with-threatened-premature-labor-and-spouses-a-cross-sectional-study-in-southwest-china
#19
Chunhua Nie, Qin Dai, Ren Zhao, Yushu Dong, Yushan Chen, Hui Ren
BACKGROUND: Threatened premature labor (TPL) is a severe obstetric complication which affects the mental and physical health of both the mother and fetus. Family resilience may have protective role against psychological distress in women experiencing these pregnancy complications. There may be resilience related risk factors in TPL women, and interplays may exist among psychological variables and within couples. This study aims to examine psychological outcomes influenced by different levels of resilience, and explore psychological interactions in TPL women, spouses, and between women and spouses...
January 31, 2017: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/28138914/obstetric-and-perinatal-outcome-in-anti-ro-ssa-positive-pregnant-women-a-prospective-cohort-study
#20
Nuria Martínez-Sánchez, Sergio Pérez-Pinto, Ángel Robles-Marhuenda, Francisco Arnalich-Fernández, María Martín Cameán, Edurne Hueso Zalvide, Jose Luis Bartha
Anti-Ro/SS-A is one specific type of antinuclear antibodies. They are in the majority of cases associated with primary Sjögren syndrome (SS) but also in Systemic Lupus Erythematosus (SLE), rheumatoid arthritis (RA), and in healthy people. During pregnancy, they are mainly associated to congenital heart block (CHB) and neonatal lupus (NL). The aim of this study was to compare the rate of maternal and fetal complications between a series of anti-Ro/SS-A positive pregnant women prospectively followed. Forty-two anti-Ro/SSA antibodies positive pregnant women that were referred to our hospital between 2011 and 2015...
January 30, 2017: Immunologic Research
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