keyword
https://read.qxmd.com/read/38536028/insights-on-obstetric-outcomes-in-pregnant-individuals-with-marfan-syndrome-evidence-from-the-national-inpatient-sample
#1
JOURNAL ARTICLE
Saeed Baradwan, Majed S Alshahrani, Khalid Khadawardi, Maha Tulbah, Osama Alomar, Abdullah Alyousef, Ibtihal A Bukhari, Ahmed Abu-Zaid
BACKGROUND: We investigated the potential association between Marfan Syndrome (MFS) and adverse obstetric outcomes using the National Inpatient Sample (NIS) database. METHODS: We utilized the International Classification of Diseases (ICD-10) system to identify relevant codes and extracted data from the NIS database covering the period 2016-2019. Descriptive statistics and χ2 tests were employed to summarize and compare baseline characteristics. Univariate and multivariate regression analyses (adjusted for age, race, hospital region, smoking status, and alcohol misuse) were conducted to evaluate association between MFS and adverse obstetric outcomes...
March 27, 2024: Minerva obstetrics and gynecology
https://read.qxmd.com/read/38525402/comparison-of-misoprostol-with-foley-catheter-vs-misoprostol-alone-for-cervical-ripening-and-induction-of-labor-in-patients-with-premature-rupture-of-membrane-a-randomized-clinical-trial-study
#2
JOURNAL ARTICLE
Seyyedeh Azam PoorHosseini, Masoumeh Mirteimouri, Maliheh RakhshaniFar, Seyede Houra Mousavi Vahed, Fedyeh Haghollahi
BACKGROUND: This study evaluates the effect of misoprostol alone in comparison with misoprostol with Foley catheter in preparing the cervix for induction of labor in women with premature rupture of the amniotic sac. MATERIALS AND METHODS: This randomized clinical trial study was performed from 2017 to 2019 on 206 pregnant women with singleton pregnancy and gestational age more than 36 weeks, whose rupture of the amniotic sac had occurred less than 12 hours and had a Bishop score less than 4...
2024: Advanced Biomedical Research
https://read.qxmd.com/read/38507460/effects-of-osteopathic-manipulative-treatment-on-maternal-fetal-hemodynamics-in-third-trimester-pregnant-women-a-prospective-study
#3
JOURNAL ARTICLE
Maria Luisa Arruda Correia, Fernando Maia Peixoto Filho, Saint Clair Gomes Júnior, Guilherme Ramires de Jesus
OBJECTIVE: To evaluate the maternal-fetal hemodynamic effects after osteopathic manipulative treatment by measuring vital signs and Doppler velocimetry in third-trimester pregnant women. MATERIALS AND METHODS: This is a prospective study with pregnant women undergoing outpatient follow-up and hospitalized in a ward at Instituto Fernandes Figueira/Fiocruz, between August 2021 to August 2022, during the SARS-CoV-2 pandemic. This study was registered in REBEC under Register Number RBR-9q7kvg and approved by the ethics committee under number 32216620...
2024: PloS One
https://read.qxmd.com/read/38507091/timing-of-planned-cesarean-delivery-among-patients-with-two-previous-cesarean-sections
#4
JOURNAL ARTICLE
Noa Leybovitz-Haleluya, Alla Saban, Adi Yariv, Reli Hershkovitz
OBJECTIVES: The timing of planned repeat cesarean delivery (CD) is debateful in clinical practice. Planned repeat CD is typically scheduled before the spontaneous onset of labor to minimize the risk of uterine rupture during labor and the associated risk for fetal compromise. This timing should be balanced with the potential risk of delivering an infant who could benefit from additional maturation in utero. We aim to study the influence of gestational age at the time of repeat CD on maternal and fetal complications...
March 20, 2024: Archives of Gynecology and Obstetrics
https://read.qxmd.com/read/38504469/oligodendrocyte-progenitor-cells-fate-after-neonatal-asphyxia-puzzling-implications-for-the-development-of-hypoxic-ischemic-encephalopathy
#5
JOURNAL ARTICLE
Justyna Janowska, Justyna Gargas, Karolina Zajdel, Michal Wieteska, Kamil Lipinski, Malgorzata Ziemka-Nalecz, Malgorzata Frontczak-Baniewicz, Joanna Sypecka
Premature birth or complications during labor can cause temporary disruption of cerebral blood flow, often followed by long-term disturbances in brain development called hypoxic-ischemic (HI) encephalopathy. Diffuse damage to the white matter is the most frequently detected pathology in this condition. We hypothesized that oligodendrocyte progenitor cell (OPC) differentiation disturbed by mild neonatal asphyxia may affect the viability, maturation, and physiological functioning of oligodendrocytes. To address this issue, we studied the effect of temporal HI in the in vivo model in P7 rats with magnetic resonance imaging (MRI), microscopy techniques and biochemical analyses...
March 19, 2024: Brain Pathology
https://read.qxmd.com/read/38497872/in-vitro-inhibition-of-uterine-contractions-using-electrospun-nanofibers-loaded-with-nifedipine-and-ml7
#6
JOURNAL ARTICLE
Y Karasu, M Demeli Ertuş, D Önal, B Topçu, H Eroğlu, B Pehlivanoğlu
OBJECTIVE: To formulate a nanofiber-based controlled drug delivery system that could be effective in preventing uterine contractions and can be used for the treatment of preterm labor. PATIENTS AND METHODS: We utilized uterine tissue samples obtained from ten pregnant women who underwent cesarean section at term to investigate the effect of nanofibers on spontaneous and induced myometrial contractions. We prepared nifedipine and ML7-loaded nanofibers using the electrospinning method with Poly(D,L-lactide-co-glycolide) (PLGA) polymer, resulted in seven groups of nanofibers, including a control group...
March 2024: European Review for Medical and Pharmacological Sciences
https://read.qxmd.com/read/38492714/systemic-lupus-erythematosus-is-associated-with-an-increased-frequency-of-spontaneous-preterm-births-systematic-review-and-meta-analysis
#7
REVIEW
Carolien N H Abheiden, Birgit S Blomjous, Ciska Slaager, Anadeijda J E M C Landman, Johannes C F Ket, Jane E Salmon, Jill P Buyon, Martijn W Heymans, Johanna I P DE Vries, Irene E M Bultink, Marjon A DE Boer
OBJECTIVE: Preterm birth (PTB) is one of the most frequent complications of pregnancies in women with systemic lupus erythematosus (SLE). The high indicated PTB proportion due to hypertensive disorders of pregnancy and/or fetal growth restriction is well known, and preventive measures as well as screening for early detection are performed. The risk of spontaneous PTB is less well recognized. The purpose of this study is to determine the proportions of spontaneous and indicated PTB in pregnancies of women with SLE DATA SOURCES: A systematic literature search using Pubmed, Embase, Web of Science and Google Scholar was performed in June 2021 STUDY ELIGIBILITY CRITERIA: Studies in pregnant women with SLE reporting spontaneous and indicated PTB rates were selected...
March 14, 2024: American Journal of Obstetrics and Gynecology
https://read.qxmd.com/read/38492584/a-systematic-review-of-economic-evaluation-of-artificial-intelligence-based-screening-for-eye-diseases-from-possibility-to-reality
#8
REVIEW
Hongkang Wu, Kai Jin, Chee Chew Yip, Victor Koh, Juan Ye
Artificial Intelligence (AI) has become a focus of research in the rapidly evolving field of ophthalmology. Nevertheless, there is a lack of systematic studies on the health economics of AI in this field. We examine studies from the PubMed, Google Scholar, and Web of Science databases that employed quantitative analysis, retrieved up to July 2023. Most of the studies indicate that AI leads to cost savings and improved efficiency in ophthalmology. On the other hand, some studies suggest that using AI in healthcare may raise costs for patients, especially when taking into account factors such as labor costs, infrastructure, and patient adherence...
March 15, 2024: Survey of Ophthalmology
https://read.qxmd.com/read/38487473/developing-and-evaluating-a-predictive-model-for-neonatal-hyperbilirubinemia-based-on-ugt1a1-gene-polymorphism-and-clinical-risk-factors
#9
JOURNAL ARTICLE
Zhaoyang Cui, Wensheng Shen, Xuetong Sun, Yan Li, Ying Liu, Zhiyong Sun
BACKGROUND: Neonatal hyperbilirubinemia (NHB) is one of the most common diseases in the neonatal period. Without timely diagnosis and treatment, it can lead to long-term complications. In severe cases, it may even result in fatality. The UGT1A1 gene and clinical risk factors play important roles in the development and progression of NHB. METHODS: In this study, we conducted a cohort study and analyzed 3258 newborns from the Jilin Women And Children Health Hospital in northern China, including 372 children with hyperbilirubinemia...
2024: Frontiers in Pediatrics
https://read.qxmd.com/read/38481196/anaphylaxis-induced-premature-uterine-contractions-a-case-report-and-literature-review
#10
JOURNAL ARTICLE
Puntabut Warintaksa, Waranyu Lertrat, Roberto Romero, Pornpun Vivithanaporn, Paninee Mongkolsuk, Threebhorn Kamlungkuea, Rapeewan Settacomkul, Pisut Pongchaikul, Piya Chaemsaithong
BACKGROUND: Preterm labor is caused by multiple etiologies, including intra-amniotic infection and/or intra-amniotic inflammation, vascular disorders, cervical disease, decidual senescence, and breakdown of maternal-fetal tolerance. Accumulating evidence in vivo and in vitro has shown that an allergic reaction, including anaphylaxis, can induce preterm uterine contractions. This report describes a case of a pregnant woman who developed anaphylaxis and regular uterine contractions after the ingestion of a strawberry-coated biscuit...
March 13, 2024: BMC Pregnancy and Childbirth
https://read.qxmd.com/read/38463868/birth-weight-discordance-and-adverse-neonatal-outcomes-in-appropriately-grown-premature-twins
#11
JOURNAL ARTICLE
Ling Yang, Yan Zhou, Jie Qiu, Nacheng Lin, Ning Gu, Yimin Dai
OBJECTIVE: This study aimed to analyze the clinical characteristics of birth weight discordant twins (BWDT) who were premature and appropriate-for-gestational-age or large-for-gestational-age. Additionally, it assessed the impact of birth weight discordance on the prognosis of appropriately grown premature twins, and investigated the effect of maternal factors on neonatal outcomes. STUDY DESIGN: This retrospective cohort study included twins who were born alive after preterm labor at the Nanjing Drum Tower Hospital from January 2018 to December 2021, along with their mothers...
March 15, 2024: Heliyon
https://read.qxmd.com/read/38455965/significance-of-cervical-secretion-culture-in-predicting-maternal-and-fetal-outcome-in-pregnant-women-with-premature-rupture-of-membranes-a-retrospective-cohort-study
#12
JOURNAL ARTICLE
Zhenna Wang, Xiaoyan Xiu, Liying Zhong, Yi Wang, Zhuanji Fang, Shunhe Lin, Huihui Huang
Background: To investigate the clinical value of cervical secretion culture in pregnant women with premature rupture of membranes (PROM) in predicting maternal and fetal outcomes. Methods: We retrospectively reviewed clinical records of pregnant women who underwent obstetric examination and delivered in Fujian Maternal and Child Healthcare from December 2013 to December 2016. Pregnant women with a clear diagnosis of PROM, who underwent cervical secretion culture immediately after hospital admission were selected for the study...
2024: Frontiers in Pharmacology
https://read.qxmd.com/read/38454336/assessing-pre-eclampsia-awareness-among-pregnant-women-in-syria-a-cross-sectional-study-on-knowledge-and-perceptions
#13
JOURNAL ARTICLE
Haidara Bohsas, Hidar Alibrahim, Sarya Swed, Yasmeen Abouainain, Ahmed Aljabali, Samaa Masoud, Heba Haj Saleh, Tony Aldawoud, Fahima Taleb, Raneem Alnassif Alsheikh, Hassan Fawaz, Danya Mourad, Waleed Farouk Mohamed, Reham Aboushady, Wael Hafez
BACKGROUND: Pre-eclampsia (PE) is a major contributor to morbidity and mortality in mothers worldwide. Adequate understanding of this condition improves treatment, control, and prevention. This study evaluated preeclampsia awareness among pregnant women in Syria, and the characteristics related to awareness adequacy. METHODS: This national cross-sectional study was conducted in Syria between 25 October and November 19, 2022. We included pregnant females of all age groups from all Syrian governorates...
March 7, 2024: BMC Pregnancy and Childbirth
https://read.qxmd.com/read/38425081/determinants-of-preterm-premature-rupture-of-membranes-and-associated-perinatal-and-maternal-outcomes-at-general-justice-gizenga-mpanza-hospital-south-africa
#14
JOURNAL ARTICLE
Ravindranath Rattan, Hariram Ramnarain
Preterm Premature Rupture of Membranes (PPROM) is defined as the rupture of fetal membranes prior to the onset of labor, before 37 weeks gestation and remains a significant obstetric complication of pregnancy with high rates of perinatal morbidity and mortality worldwide. The aim of our study was to establish the determinants of PPROM <34 weeks at this GJG MRH hospital which has a high incidence of PPROM. It was a descriptive , retrospective chart review of women diagnosed with PPROM over a 1 year period from 1st of January 2018 to 31st of December 2018...
February 28, 2024: African Journal of Reproductive Health
https://read.qxmd.com/read/38424482/prevalence-and-adverse-outcomes-of-twin-pregnancy-in-eastern-africa-a-systematic-review-and-meta-analysis
#15
JOURNAL ARTICLE
Tamirat Getachew, Abraham Negash, Adera Debella, Elias Yadeta, Magersa Lemi, Bikila Balis, Tegenu Balcha, Habtamu Bekele, Mohammed Abdurke, Addisu Alemu, Kasiye Shiferaw, Addis Eyeberu
INTRODUCTION: Multiple pregnancies are much more common today than they were in the past. Twin pregnancies occur in about 4% of pregnancies in Africa. Adverse pregnancy outcome was more common in twin pregnancy than in singleton pregnancy. There is no pooled evidence on the burden and adverse pregnancy outcome of twin pregnancy in eastern Africa. Thus, this systematic review and meta-analysis were conducted to assess the prevalence and adverse pregnancy outcomes of twin pregnancies. METHODS: This systematic review and meta-analysis covers published and unpublished studies searched from different databases (PubMed, CINAHL (EBSCO), EMBASE, DOAJ, Web of Sciences, MEDLINE, Cochrane Library, SCOPUS, Google Scholar, and Google search)...
February 29, 2024: BMC Pregnancy and Childbirth
https://read.qxmd.com/read/38418200/prenatal-exposure-to-intra-amniotic-infection-with-ureaplasma-species-increases-the-prevalence-of-bronchopulmonary-dysplasia
#16
JOURNAL ARTICLE
Tomoko Yamamoto, Makoto Nomiyama, Yuko Oshima, Takeshi Ono, Yutaka Kozuma, Yukiko Nakura, Itaru Yanagihara, Keisuke Tsumura, Masatoshi Yokoyama
OBJECTIVES: The present study investigated the relationship between bronchopulmonary dysplasia (BPD) and intra-amniotic infection with Ureaplasma species. METHODS: This was a single-center, retrospective cohort study. Patients with singleton pregnancies who underwent inpatient management at our department for preterm premature rupture of membranes (PPROM), preterm labor, cervical insufficiency, and asymptomatic cervical shortening at 22-33 gestational weeks were included...
December 2024: Journal of Maternal-fetal & Neonatal Medicine
https://read.qxmd.com/read/38413908/magnitude-of-neonatal-asphyxia-and-its-predictors-among-newborns-at-public-hospitals-of-wolaita-zone-in-southern-ethiopia-2023
#17
JOURNAL ARTICLE
Shewazerf Gizachew, Girma Wogie, Mekasha Getnet, Arega Abebe Lonsako
BACKGROUND: Neonatal asphyxia is one of preventable causes of neonatal mortality throughout the world. It could be improved by early detection and control of the underlying causes. However, there was lack of evidence on it in the study setting. Thus, the aim of this study was to assess the magnitude and predictors of neonatal asphyxia among newborns at public hospitals of Wolaita Zone in Southern Ethiopia. METHOD: A facility-based cross-sectional study was done among 330 mothers with neonates in selected public hospitals...
February 27, 2024: BMC Pediatrics
https://read.qxmd.com/read/38410759/clinical-significance-and-main-parameters-promoting-the-breast%C3%A2-feeding-strategy-review
#18
REVIEW
Eleni Nixarlidou, Chrysoula Margioula-Siarkou, Aristarchos Almperis, Eleftherios Vavoulidis, Antonio Simone Laganà, Konstantinos Dinas, Stamatios Petousis
Breastfeeding provides numerous nutritional and immunological benefits, promotes neurological and cognitive development, and protects against chronic and infectious diseases, rendering it beneficial to the survival and well-being of infants. According to international recommendations, infants should be exclusively breastfed for the first 6 months. However, despite global health recommendations and funding initiatives, exclusive breastfeeding rates remain low worldwide. A number of studies attribute the low rates to factors that can be grouped into demographic, psychosocial, economic and midwifery factors, and outline the profile of each mother who opts to exclusively breastfeed her infant...
2024: Med Int (Lond)
https://read.qxmd.com/read/38408929/selective-feticide-in-dichorionic-diamniotic-dcda-twins-complicated-with-previable-premature-rupture-of-membrane-before-24-weeks-may-be-a-safe-therapeutic-alternative-to-ongoing-pregnancy
#19
JOURNAL ARTICLE
Caixia Zhu, Haiyan Liu, Hui Zhu, Linhuan Huang
BACKGROUND: To date, there are no clinical guidelines for dichorionic diamniotic (DCDA) twins complicated with previable premature rupture of membrane (PV-ROM) before 24 weeks of gestation. The typical management options including expectant management and/or pregnant termination, induce the risks of fetal mortality and morbidity. OBJECTIVE: To explore the feasibility selective feticide in DCDA twins complicated with PV-ROM. STUDY DESIGN: A Retrospective cohort study, enrolling 28 DCDA twins suffering from PV-ROM in a tertiary medical center from Jan 01 2012 to Jan 01 2022...
February 26, 2024: BMC Pregnancy and Childbirth
https://read.qxmd.com/read/38403163/role-of-platelet-activating-factor-paf-as-a-mediator-of-inflammatory-diseases-and-preterm-delivery
#20
REVIEW
Hanan Hamimi Wahid, Fatin Najihah Anahar, Nurul Husna Isahak, Juwairiyah Mohd Zoharodzi, Siti Nur Lina Mohammad Khoiri, Nurul Hayati Mohamad Zainal, Norhidayah Kamarudin, Hamizah Ismail, Mohammed Imad Al-Deen Mustafa Mahmud
Nearly 70% of preterm deliveries occur spontaneously, and the clinical pathways involved include preterm labor (PTL) and preterm premature rupture of membranes (pPROM). Prediction of preterm delivery is considered crucial due to the significant effects of preterm birth on health and the economy at both the personal and community levels. Although similar inflammatory processes occur in both term and preterm delivery, the premature activation of these processes or exaggerated inflammatory response triggered by infection or sterile factors leads to preterm delivery...
February 23, 2024: American Journal of Pathology
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