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First trimester ultrasound

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https://www.readbyqxmd.com/read/29221765/advances-in-fetal-echocardiography
#1
REVIEW
Helena M Gardiner
The development of fetal echocardiography and success in prenatal cardiac screening programs over the past 30 years has been driven by technical innovation and influenced by the different approaches of the various specialties practicing it. Screening for congenital heart defects no longer focuses on examining a limited number of pregnant women thought to be at increased risk, but instead forms an integrated part of a high-quality anatomical ultrasound performed in the second trimester using the 'five-transverse view' protocol...
December 5, 2017: Seminars in Fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29216009/the-first-trimester-aneuploidy-biochemical-markers-in-ivf-icsi-patients-have-no-additional-benefit-compared-to-spontaneous-conceptions-in-the-prediction-of-pregnancy-complications
#2
Iwona Szymusik, Przemyslaw Kosinski, Katarzyna Kosinska-Kaczynska, Damian Warzecha, Anetta Karwacka, Bartosz Kaczynski, Miroslaw Wielgos
OBJECTIVES: The aim of this study was to determine if the levels of biochemical aneuploidy markers in in vitro fertilisation (IVF)/intracytoplasmic sperm injection (ICSI) pregnancies differ from those in spontaneous pregnancies and to verify if biochemical markers could predict pregnancy outcome in IVF/ICSI gestations. METHODS: This was a prospective observational study performed in a group of 551 patients who underwent a combined first trimester prenatal screening (ultrasound scan and serum markers)...
December 7, 2017: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/29193896/in-utero-ultrasound-diagnosis-of-corpus-callosum-agenesis-leading-to-the-identification-of-orofaciodigital-type-1-syndrome-in-female-fetuses
#3
Caroline Alby, Lucile Boutaud, Maryse Bonnière, Sophie Collardeau-Frachon, Laurent Guibaud, Estelle Lopez, Ange-Line Bruel, Bernard Aral, Pascale Sonigo, Philippe Roth, Claude Vibert-Guigue, Vanina Castaigne, Bruno Carbonne, Nicole Joyé, Laurence Faivre, Marie-Pierre Cordier, Antoinette Bernabe Gelot, Maurizio Clementi, Isabella Mammi, Michel Vekemans, Féréchté Razavi, Marie Gonzales, Christel Thauvin-Robinet, Tania Attié-Bitach
BACKGROUND: OFD1 syndrome is a rare ciliopathy inherited on a dominant X-linked mode, typically lethal in males in the first or second trimester of pregnancy. It is characterized by oral cavity and digital anomalies possibly associated with cerebral and renal signs. Its prevalence is between 1/250,000 and 1/50,000 births. It is due to heterozygous mutations of OFD1 and mutations are often de novo (75%). Familial forms show highly variable phenotypic expression. OFD1 encodes a protein involved in centriole growth, distal appendix formation, and ciliogenesis...
November 28, 2017: Birth Defects Research
https://www.readbyqxmd.com/read/29175064/difference-between-mean-gestational-sac-diameter-and-crown-rump-length-as-a-marker-of-first-trimester-pregnancy-loss-after-in%C3%A2-vitro-fertilization
#4
Joshua D Kapfhamer, Sruthi Palaniappan, Karen Summers, Kristen Kassel, Abigail C Mancuso, Ginny L Ryan, Divya K Shah
OBJECTIVE: To investigate whether the difference between mean gestational sac diameter and crown-rump length (mGSD - CRL) is associated with first-trimester pregnancy loss or adverse pregnancy outcomes after in vitro fertilization (IVF) and to determine if mGSD - CRL is a better predictor of pregnancy loss than either measurement alone. DESIGN: Retrospective cohort study. SETTING: University hospital. PATIENT(S): A total of 1,243 IVF cycles with fresh or cryopreserved autologous embryo transfers resulting in singleton gestations performed at the University of Iowa Hospitals and Clinics from January 2005 through December 2014...
November 23, 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/29162956/risk-assessment-at-11-14-week-antenatal-visit-a-tertiary-referral-center-experience-from-south-india
#5
Anusha Vellamkondu, Akhila Vasudeva, Rajeshwari G Bhat, Asha Kamath, Sapna V Amin, Lavanya Rai, Pratap Kumar
Background: Present study carried out in a tertiary referral hospital in South India attempts to determine the predictive value of integrated screening at 11-14-week antenatal visit. Objectives: To determine the detection rate of fetal abnormalities at 11-14 weeks and also to predict the placental dysfunction disorders based on early integrated evaluation. Method: Integrated screening performed on 440 women between 11 and 14 weeks, including detailed maternal history [medical history, bad obstetric history (BOH)], body mass index (BMI), mean arterial pressure (MAP), detailed ultrasound and maternal serum biochemistry as part of combined first-trimester screening for aneuploidy...
December 2017: Journal of Obstetrics and Gynaecology of India
https://www.readbyqxmd.com/read/29157099/the-association-of-first-trimester-uterine-arteries-doppler-velocimetry-with-different-clinical-phenotypes-of-hypertensive-disorders-of-pregnancy-a-longitudinal-study
#6
Tamara Stampalija, Lorenzo Monasta, Daniela D Di Martino, Mariachiara Quadrifoglio, Leila Lo Bello, Giuseppina D'Ottavio, Sara Zullino, Cristina Mastroianni, Daniela Casati, Valentina Signorelli, Eleonora Rosti, Vera Cecotti, Matteo Ceccarello, Enrico Ferrazzi
INTRODUCTION: Current classification of hypertensive disorders of pregnancy (HDP) is mostly based on temporal classification differentiating HDP according to early and late onset of the disease. However, epidemiological and clinical data suggest that there are two different clinical phenotypes of HDP that coexist at any gestational age: HDP associated to intrauterine growth restriction (HDP-IUGR) and HDP associated to appropriate for gestational age fetal growth (HDP-AGAf). The aim of the study was to evaluate the association of first trimester uterine arteries (UtA) by Doppler velocimetry, and maternal risk factors with HDP according to two different classifications: one based on gestational age at delivery (early- and late-HDP), and one based on longitudinal ultrasound evaluation of fetal growth (HDP-IUGR and HDP-AGAf), independently of the gestational age...
November 20, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29157037/fetal-nuchal-translucency-in-severe-congenital-heart-defects-experiences-in-northern-finland
#7
Julia Alanen, Markku Leskinen, Mikko Sairanen, Teemu Korpimaki, Heikki Kouru, Mika Gissler, Markku Ryynanen, Jaana Nevalainen
OBJECTIVE: To evaluate the performance of first trimester measurement of fetal nuchal translucency (NT) in detection of severe congenital heart defects (CHDs). METHODS: During the study period of 1.1.2008 - 31.12.2011 NT was measured in 31 144 women as a part of voluntary first trimester screening program for Down's syndrome in Northern Finland. NT was measured by personnel trained on the job by experienced staff. No certification or annual audits are required in Finland...
November 20, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29136193/early-first-trimester-uteroplacental-flow-and-the-progressive-disintegration-of-spiral-artery-plugs-new-insights-from-contrast-enhanced-ultrasound-and-tissue-histopathology
#8
V H J Roberts, T K Morgan, P Bednarek, M Morita, G J Burton, J O Lo, A E Frias
STUDY QUESTION: Does the use of a vascular contrast agent facilitate earlier detection of maternal flow to the placental intervillous space (IVS) in the first trimester of pregnancy? SUMMARY ANSWER: Microvascular filling of the IVS was demonstrated by contrast-enhanced ultrasound from 6 weeks of gestation onwards, earlier than previously believed. WHAT IS KNOWN ALREADY: During placental establishment and remodeling of maternal spiral arteries, endovascular trophoblast cells invade and accumulate in the lumen of these vessels to form 'trophoblast plugs'...
November 10, 2017: Human Reproduction
https://www.readbyqxmd.com/read/29129159/third-trimester-ultrasound-accuracy-and-delivery-outcome-in-obese-and-morbid-obese-pregnant-women
#9
Sawsan Al-Obaidly, Abdullah Al-Ibrahim, Najah Saleh, Mariam Al-Belushi, Zeena Al-Mansouri, Najat Khenyab
OBJECTIVE: Several studies have highlighted the negative impact of maternal obesity on ultrasound accuracy for fetal weight estimation (EFW). However, the evidence is conflicting. We aimed in our study to find if the ultrasound accuracy for EFW would differ or decrease in obese and morbid obesity classes. We also studied the mode of delivery within the same cohort. METHODS: It is a retrospective study of obese patients with recorded BMI ≥30 kg/m2, class I and II (BMI: 30-39...
November 22, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29124818/diagnosis-and-management-of-patients-with-enhanced-myometrial-vascularity-associated-with-retained-products-of-conception
#10
Yvette S Groszmann, Amie Lynn Healy Murphy, Beryl R Benacerraf
OBJECTIVES: We performed this study to assess the complication rate, including the estimated amount of blood loss, in patients who underwent dilation and curettage for treatment of retained products of conception with markedly enhanced myometrial vascularity mimicking arteriovenous malformations. METHODS: This is a retrospective medical records review study of patients with retained products of conception with enhanced myometrial vascularity presenting to our ultrasound unit between August 1, 2015 and August 1, 2017...
November 10, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29119588/an-early-pregnancy-unit-in-the-united-states-an-effective-method-for-evaluating-first-trimester-pregnancy-complications
#11
Polina Rovner, Elaine Stickrath, Meredith Alston, Kirsten Lund
In the United Kingdom, early pregnancy assessment clinics have existed since the early 1990s and have become the reference standard for evaluating and treating women with first-trimester pregnancy complications. These units have now been established in many countries and have been found to be effective and efficient, saving money and unnecessary emergency department visits and hospital admissions. To our knowledge, no such model has been described in the United States. A PubMed search using a combination of "early pregnancy unit," "early pregnancy assessment clinic," and "United States," "U...
November 9, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/29107981/prevalence-and-risk-factors-of-monochorionic-diamniotic-twinning-after-assisted-reproduction-a-six-year-experience-base-on-a-large-cohort-of-pregnancies
#12
Bing Song, Zhao-Lian Wei, Xiao-Feng Xu, Xue Wang, Xiao-Jin He, Huan Wu, Ping Zhou, Yun-Xia Cao
OBJECTIVE: To characterize the incidence and risk factors for monochorionic diamniotic(MC-DA) twinning after assisted reproductive technologies (ART). DESIGN: Retrospective population-based study. SETTING: The study was conducted in China; Department of Reproductive Medicine Center at The First Affiliated Hospital of Anhui Medical University. POPULATION: A cohort of 8860 clinical pregnancies after embryo transfer (ET) carried out in our center between 2011 and 2016 were retrospectively analyzed for the incidence of MC-DA twinning...
2017: PloS One
https://www.readbyqxmd.com/read/29101986/acr-appropriateness-criteria-%C3%A2-multiple-gestations
#13
Phyllis Glanc, David A Nyberg, Nadia J Khati, Sandeep Prakash Deshmukh, Kika M Dudiak, Tara Lynn Henrichsen, Liina Poder, Thomas D Shipp, Lynn Simpson, Therese M Weber, Carolyn M Zelop
Women with twin or higher-order pregnancies will typically have more ultrasound examinations than women with a singleton pregnancy. Most women will have at minimum a first trimester scan, a nuchal translucency evaluation scan, fetal anatomy scan at 18 to 22 weeks, and one or more scans in the third trimester to evaluate growth. Multiple gestations are at higher risk for preterm delivery, congenital anomalies, fetal growth restriction, placenta previa, vasa previa, and velamentous cord insertion. Chorionicity and amnionicity should be determined as early as possible when a twin pregnancy is identified to permit triage of the monochorionic group into a closer surveillance model...
November 2017: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/29097177/first-trimester-screening-for-early-and-late-preeclampsia-using-maternal-characteristics-biomarkers-and-estimated-placental-volume
#14
Jiri Sonek, David Krantz, Jon Carmichael, Cathy Downing, Karen Jessup, Ziad Haidar, Shannon Ho, Terrence Hallahan, Harvey J Kliman, David McKenna
BACKGROUND: Preeclampsia is a major cause of perinatal morbidity and mortality. First-trimester screening has been shown to be effective in selecting patients at an increased risk for preeclampsia in some studies. OBJECTIVE: We sought to evaluate the feasibility of screening for preeclampsia in the first trimester based on maternal characteristics, medical history, biomarkers, and placental volume. STUDY DESIGN: This is a prospective observational nonintervention cohort study in an unselected US population...
October 31, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29096644/serum-periostin-levels-in-early-in-pregnancy-are-significantly-altered-in-women-with-miscarriage
#15
A Freis, J Schlegel, R J Kuon, A Doster, J Jauckus, T Strowitzki, A Germeyer
BACKGROUND: Miscarriage is a common complication in pregnancy and there is still a lack of biomarkers usable in asymptomatic patients before the event occurs. Periostin (PER), whose levels rise particularly during injury or inflammation, has been shown to play an important local role in implantation and early embryonic development. As PER has been described as a biomarker in various medical conditions we intended to evaluate if changes in PER serum levels may help to identify women at risk for spontaneous abortion in the first trimester...
November 2, 2017: Reproductive Biology and Endocrinology: RB&E
https://www.readbyqxmd.com/read/29095006/-influence-of-physical-exercise-during-pregnancy-on-newborn-weight-a-randomized-clinical-trial
#16
Raquel Rodríguez-Blanque, Juan Carlos Sánchez-García, Antonio Manuel Sánchez-López, Norma Mur-Villar, Rafael Fernández-Castillo, María José Aguilar Cordero
INTRODUCTION: Recent studies have proved that physical activity of the pregnant woman brings benefits not only for the mother but also for the fetus, given that it decreases the number of macrosomic newborns and their negative consequences in both of them. OBJECTIVE: To analyze in pregnant women the influence of a moderate physical activity program in the aquatic environment on the weight of the newborn. MATERIAL AND METHODS: A randomized clinical trial with 140 healthy pregnant women, aged between 21 and 43 years, divided into two groups, study (GE, n = 70) and control (GC, n = 70)...
July 28, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/29080223/comparison-of-first-tier-cell-free-dna-screening-for-common-aneuploidies-with-conventional-publically-funded-screening
#17
Sylvie Langlois, JoAnn Johnson, François Audibert, Jean Gekas, Jean-Claude Forest, André Caron, Keli Harrington, Melanie Pastuck, Hasna Meddour, Amélie Tétu, Julian Little, François Rousseau
OBJECTIVE: This study evaluates the impact of offering cell-free DNA (cfDNA) screening as a first-tier test for trisomies 21 and 18. METHODS: This is a prospective study of pregnant women undergoing conventional prenatal screening who were offered cfDNA screening in the first trimester with clinical outcomes obtained on all pregnancies. RESULTS: A total of 1198 pregnant women were recruited. The detection rate of trisomy 21 with standard screening was 83% with a false positive rate (FPR) of 5...
October 28, 2017: Prenatal Diagnosis
https://www.readbyqxmd.com/read/29073631/isolated-cleft-lip-and-palate-maxillary-gap-sign-and-palatino-maxillary-diameter-at-11-13-weeks
#18
Robert Lachmann, Uwe Schilling, Detlef Brückmann, Alexander Weichert, Andreas Brückmann
OBJECTIVE: To evaluate the maxillary gap sign and describe markers for the first-trimester diagnosis of isolated cleft lip and palate (CLP) at 11-13 weeks. METHODS: Firstly, this was a prospective assessment of 1,087 fetuses including 5 cases of isolated CLP in 2 centers which were referred for the 11-13 weeks scan. Secondly, intra- and interobserver variability of the maxillary gap sign was evaluated for observers R.L. and A.B. in 2 sessions (affected cases vs...
October 26, 2017: Fetal Diagnosis and Therapy
https://www.readbyqxmd.com/read/29060631/automatic-measurement-of-fetal-nuchal-translucency-from-three-dimensional-ultrasound-data
#19
Siqing Nie, Jinhua Yu, Ping Chen, Yuanyuan Wang, Yi Guo, Jian Qiu Zhang
The Nuchal translucency (NT), which is the collection of fluid at the back of the fetal neck, is related to chromosomal defects and early cardiac failure in first trimester of pregnancy. In clinic, the thickness of NT is used as an important marker in prenatal screening, and is manually measured by sonographers in the mid-sagittal plane. In this paper, an automatic method based on dynamic programming is proposed to detect the thickness and area of NT in the mid-sagittal plane. Furthermore, the volume of NT in the whole three-dimensional ultrasound data is also measured...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29057433/screening-for-trisomy-21-based-on-maternal-age-nuchal-translucency-measurement-first-trimester-biochemistry-and-quantitative-and-qualitative-assessment-of-the-flow-in-the-dv-the-assessment-of-efficacy
#20
Bartosz Czuba, Dariusz Zarotyński, Mariusz Dubiel, Dariusz Borowski, Piotr Węgrzyn, Wojciech Cnota, Małgorzata Reska-Nycz, Marek Mączka, Mirosław Wielgoś, Krzysztof Sodowski, Dawid Serafin, Anna Kubaty, Grzegorz H Bręborowicz
OBJECTIVES: The aim of the study was to compare effects of addition of two methods of ductus venosus (DV) flow assessment: qualitative - the assessment of shape of the A-wave (positive or negative), and quantitative - based on the pulsatility index for veins (DVPI) to the basic screening for trisomy 21 at 11 to 13 + 6 weeks of pregnancy. MATERIAL AND METHODS: The ultrasound examination was performed in 8230 fetuses in singleton pregnancies at 11- -13 + 6 wks, as a part of a routine screening for chromosomal defects...
2017: Ginekologia Polska
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