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First trimester ultrasound

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https://www.readbyqxmd.com/read/27889224/fetal-megacystis-a-systematic-review
#1
REVIEW
K Taghavi, C Sharpe, M D Stringer
: Fetal megacystis is variably defined and understood. The literature on fetal megacystis was systematically reviewed, focusing on prenatal diagnosis, associations and outcomes. This yielded a total of 18 primary references and eight secondary references. Fetal megacystis has an estimated first-trimester prevalence of between 1:330 and 1:1670, with a male to female ratio of 8:1. In the first trimester, megacystis is most commonly defined as a longitudinal bladder dimension of ≥7 mm...
October 8, 2016: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/27888703/the-association-between-prenatal-atrioventricular-septal-defects-and-chromosomal-abnormalities
#2
Maddalena Morlando, Amarnath Bhide, Alessandra Familiari, Asma Khalil, José Morales-Roselló, Aris T Papageorghiou, Julene S Carvalho
OBJECTIVE: Atrioventricular septal defect is associated with a high risk of a chromosomal abnormality, particularly trisomy 21. The aim of this study is to assess the rate of trisomy 21 in fetuses diagnosed with an atrioventricular septal defect and to examine the influence of prior screening on the rate of trisomy 21. METHODS: Electronic ultrasound database was searched to identify fetuses diagnoses with an atrioventricular septal defect from 2002 to 2014. Rate of trisomy 21 and other aneuploidies was calculated among fetuses with normal situs...
October 29, 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/27862084/intra-and-inter-observer-reproducibility-and-generalizability-of-first-trimester-uterine-artery-pulsatility-index-by-transabdominal-and-transvaginal-ultrasound
#3
Laura Marchi, Eva Zwertbroek, Judith Snelder, Maaike Kloosterman, Caterina Maddalena Bilardo
OBJECTIVES: The primary aim of the study was to assess intra-observer and inter-observer reproducibility and generalizability (general reliability) of first trimester Doppler measurements of uterine arteries (UtA) performed both transabdominally (TA) and transvaginally (TV). Secondary aims were to investigate whether maternal BMI and acquisition modality (transabdominal or transvaginal) affect feasibility and reliability of UtA Doppler evaluation. METHODS: Singleton pregnancies between 11(+0) and 13(+6) weeks underwent TA and TV Doppler measurements of UtA prospectively, blindly and independently by Fetal Medicine Foundation-accredited operators...
November 16, 2016: Prenatal Diagnosis
https://www.readbyqxmd.com/read/27858960/lower-accuracy-in-prediction-of-delivery-date-in-stockholm-county-following-introduction-of-new-guidelines
#4
Hans Wessel, Tommy Nyberg
INTRODUCTION: In the Stockholm County new guidelines for predicting the day of delivery was introduced in 2010. Recent clinical use has indicated that the predictive quality might be suboptimal. This study compares the accuracy of three equations applied during the first (crown-rump length (CRL) or bi-parietal diameter (BPD)) and second trimesters (BPD or BPD combined with femur length (FL)). MATERIAL AND METHODS: In 14,239 ultrasound exams the accuracy of estimated delivery date was compared using median deviations from actual birth date, proportion of postterms, births within +/- 7 days of estimated delivery date, accuracy variations depending on fetal size, alternative fetal measurements obtained at the same occasion, and menstrual age...
November 17, 2016: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/27855487/transfer-of-therapeutic-genes-into-fetal-rhesus-monkeys-using-recombinant-adeno-associated-type-i-viral-vectors
#5
Thomas J Conlon, Cathryn S Mah, Christina A R Pacak, Mary B Rucker Henninger, Kirsten E Erger, Marda L Jorgensen, Charles C Lee, Alice F Tarantal, Barry J Byrne
Neuromuscular disorders such as Pompe disease (glycogen storage disease, type II), result in early and potentially irreversible cellular damage with a very limited opportunity for intervention in the newborn period. Pompe disease is due to deficiency in acid α-glucosidase (GAA) leading to lysosomal accumulation of glycogen in all cell types, abnormal myofibrillogenesis, respiratory insufficiency, neurological deficits, and reduced contractile function in striated muscle. Previous studies have shown that fetal delivery of recombinant adeno-associated virus (rAAV) encoding GAA to the peritoneal cavity of Gaa-/- mice resulted in high-level transduction of the diaphragm...
November 17, 2016: Human Gene Therapy. Clinical Development
https://www.readbyqxmd.com/read/27822346/ultrasonographic-evaluation-of-placental-cord-insertion-at-different-gestational-ages-in-low-risk-singleton-pregnancies-a-predictive-algorithm
#6
F Padula, A S Laganà, S G Vitale, L Mangiafico, L D'Emidio, P Cignini, M Giorlandino, F A Gulino, S Capriglione, C Giorlandino
OBJECTIVE: To evaluate the accuracy of ultrasound in visualizing placental cord insertion (PCI) at different gestational ages in order to recommend the most feasible period during pregnancy to identify it. Secondary aim was to propose a predictive algorithm for PCI visualization. METHODS: We performed a single-center, prospective cohort study. We enrolled patients with singleton low-risk pregnancies who underwent fetal ultrasound scan at different gestational ages...
March 28, 2016: Facts, Views & Vision in ObGyn
https://www.readbyqxmd.com/read/27822088/the-danish-fetal-medicine-database
#7
REVIEW
Charlotte Kvist Ekelund, Tine Iskov Kopp, Ann Tabor, Olav Bjørn Petersen
AIM: The aim of this study is to set up a database in order to monitor the detection rates and false-positive rates of first-trimester screening for chromosomal abnormalities and prenatal detection rates of fetal malformations in Denmark. STUDY POPULATION: Pregnant women with a first or second trimester ultrasound scan performed at all public hospitals in Denmark are registered in the database. MAIN VARIABLES/DESCRIPTIVE DATA: Data on maternal characteristics, ultrasonic, and biochemical variables are continuously sent from the fetal medicine units' Astraia databases to the central database via web service...
2016: Clinical Epidemiology
https://www.readbyqxmd.com/read/27818118/-medical-induced-abortion
#8
K Bettahar, A Pinton, T Boisramé, V Cavillon, S Wylomanski, I Nisand, D Hassoun
OBJECTIVE: Updated clinical recommendations for medical induced abortion procedure. METHODS: A systematic review of French and English literature, reviewing the evidence relating to the provision of medical induced abortion was carried out on PubMed, Cochrane Library and international scientific societies recommendations. RESULTS: The effectiveness of medical abortion is higher than 95% when the protocols are adjusted to gestational age (EL1)...
November 3, 2016: Journal de Gynécologie, Obstétrique et Biologie de la Reproduction
https://www.readbyqxmd.com/read/27816740/relation-between-the-quality-of-the-ultrasound-image-acquisition-and-the-precision-of-the-measurement-of-the-crown-rump-length-in-the-late-first-trimester-what-are-the-consequences
#9
Ferdinand Dhombres, Nathalie Roux, Stéphanie Friszer, Roger Bessis, Babak Khoshnood, Jean-Marie Jouannic
OBJECTIVE: To assess the extent to which the distribution of crown-rump length (CRL) values may be correlated with different criteria for the quality of the CRL images. STUDY DESIGN: This is a retrospective analysis of a series of 977 CRL images, by two independent observers, for the presence or the absence of 14 quality hallmarks. Inter-observer agreement for the hallmarks was assessed by the proportion of agreement and Cohen's kappa. The association between the quantiles of the CRL distribution and the presence or absence of the 14 quality hallmarks was modeled using quantile regression...
October 27, 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/27815938/visualization-and-quantitation-of-fetal-movements-by-real-time-three-dimensional-ultrasound-with-live-xplane-imaging-in-the-first-trimester-of-pregnancy
#10
Ye Lu, Taizhu Yang, Hong Luo, Feng Deng, Qianyun Cai, Weiwei Sun, Hao Song
AIM: To prove whether real-time three-dimensional (3D) ultrasound with live xPlane imaging is better in observing fetal movements than standard ultrasound imaging. METHODS: 50 healthy women with singleton pregnancies (22-43 years old) at 11 to 14 weeks of gestation underwent real-time 3D ultrasound examination with live xPlane imaging from July 2014 to February 2015. The incidence and frequency of 10 fetal movement patterns in 10 minutes were evaluated, including general movements (GMs), isolated arm movements, isolated leg movements, hiccup, stretching, breathing, startle, jaw opening, isolated head retroflexion, and isolated head anteflexion...
October 31, 2016: Croatian Medical Journal
https://www.readbyqxmd.com/read/27813114/the-value-of-the-first-trimester-ultrasound-in-the-era-of-cell-free-dna-screening
#11
Rashmi R Rao, Stephanie G Valderramos, Neil S Silverman, Christina S Han, Lawrence D Platt
OBJECTIVE: To describe the clinically relevant findings detected by the first trimester ultrasound (FTU) and to determine the additional value of the FTU compared to cell free DNA (cfDNA) alone. METHOD: Retrospective cohort study of patients undergoing a FTU at a maternal-fetal medicine referral practice. Fetal, gynecologic, and placental findings detected by ultrasound were analyzed with available cfDNA and diagnostic testing results. A subgroup analysis of positive ultrasound findings and cfDNA results was performed to assess the additional benefit of ultrasound evaluation in FT prenatal screening...
November 3, 2016: Prenatal Diagnosis
https://www.readbyqxmd.com/read/27813091/first-trimester-chorionic-bump-association-with-fetal-aneuploidy-in-a-high-risk-population
#12
Joseph R Wax, Angelina Cartin, Christian Litton, Michael G Pinette, F L Lucas
PURPOSE: To determine the relationship between the first-trimester chorionic bump and fetal aneuploidy. METHODS: This retrospective cohort study included all singleton pregnancies with chromosomal analysis and sonographic examination performed between 5 0/7 and 13 6/7 weeks from January 1, 2010 through August 15, 2015. Interobserver and intraobserver agreement for identifying a chorionic bump was evaluated by the Kappa statistic. Pregnancies with and without a chorionic bump were compared regarding patient characteristics and fetal karyotypes...
November 3, 2016: Journal of Clinical Ultrasound: JCU
https://www.readbyqxmd.com/read/27810260/automatic-detection-of-standard-sagittal-plane-in-the-first-trimester-of-pregnancy-using-3-d-ultrasound-data
#13
Siqing Nie, Jinhua Yu, Ping Chen, Yuanyuan Wang, Jian Qiu Zhang
Fetal nuchal translucency (NT) thickness is one of the most important parameters in prenatal screening. Locating the mid-sagittal plane is one of the key points to measure NT. In this paper, an automatic method for the sagittal plane detection using 3-D ultrasound data is proposed. To avoid unnecessary massive searching and the corresponding huge computation load, a model is proposed to turn the sagittal plane detection problem into a symmetry plane and axis searching problem. The deep belief network (DBN) and a modified circle detection method provide prior knowledge for the searching...
October 31, 2016: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/27802270/single-and-serial-fetal-biometry-to-detect-preterm-and-term-small-and-large-for-gestational-age-neonates-a-longitudinal-cohort-study
#14
Adi L Tarca, Edgar Hernandez-Andrade, Hyunyoung Ahn, Maynor Garcia, Zhonghui Xu, Steven J Korzeniewski, Homam Saker, Tinnakorn Chaiworapongsa, Sonia S Hassan, Lami Yeo, Roberto Romero
OBJECTIVES: To assess the value of single and serial fetal biometry for the prediction of small- (SGA) and large-for-gestational-age (LGA) neonates delivered preterm or at term. METHODS: A cohort study of 3,971 women with singleton pregnancies was conducted from the first trimester until delivery with 3,440 pregnancies (17,334 scans) meeting the following inclusion criteria: 1) delivery of a live neonate after 33 gestational weeks and 2) two or more ultrasound examinations with fetal biometry parameters obtained at ≤36 weeks...
2016: PloS One
https://www.readbyqxmd.com/read/27792241/evaluation-of-a-retrospective-diary-for-peri-conceptual-and-mid-pregnancy-drinking-in-scotland-a-cross-sectional-study
#15
Andrew Symon, Jean Rankin, Geraldine Butcher, Lesley Smith, Lynda Cochrane
Heavy episodic ('binge') drinking among women in Scotland is commonplace; pre-pregnancy drinking is associated with continued antenatal drinking. Evidence for effectiveness of standardised antenatal alcohol assessment is lacking. Alcohol-exposed pregnancies may be missed. We assessed peri-conceptual and mid-pregnancy consumption using a week-long retrospective diary and standard alcohol questionnaires, and evaluated the agreement between these instruments MATERIAL AND METHODS: Cross-sectional study in two Scottish health board areas involving 510 women attending mid-pregnancy ultrasound scan clinics...
October 28, 2016: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/27777190/-correlation-analysis-of-fetal-middle-cerebral-artery-peak-systolic-velocity-cardiothoracic-ratio-and-crown-rump-length-in-early-pregnancy
#16
Xu-Jie Deng, Cui-Hua Chen, Yu-Wen Qiu, Shu-Fang Xiao, Shu-Xin Liao, Mei Zhong, Fang Yang
OBJECTIVE: To explore the pattern of variations in middle cerebral artery peak systolic velocity (MCA PSV) and cardiothoracic ratio (CTR) during early pregnancy, establish their reference ranges and explore their correlation with the crown-rump length (CRL). METHODS: A total of 522 pregnant women with normal findings in antenatal examinations underwent routine color Doppler ultrasound examination to collect the data of MCA PSV, CTR and CRL. The reference ranges of MCA PSV and CTR for different CRL levels were established, and the correlation of MCA PSV and CTR with CRL was analyzed...
October 20, 2016: Nan Fang Yi Ke da Xue Xue Bao, Journal of Southern Medical University
https://www.readbyqxmd.com/read/27776483/induced-abortion-%C3%A2-impact-on-a%C3%A2-subsequent-pregnancy-in-first-time-mothers-a-registry-based-study
#17
Susanna Holmlund, Tommi Kauko, Jaakko Matomäki, Miia Tuominen, Juha Mäkinen, Päivi Rautava
BACKGROUND: To date, several studies concerning the effects of induced abortion (IA) on women's later psychosocial well-being and future delivery complications have been published. However, the lack of reports on woman's physical well-being during their first full-term pregnancy occurring after IA is what inspired the current study. Here, we evaluate the physical well-being and use of maternity services of first-time mothers with a history of IA. METHODS: Finnish National Birth Registry data from 2008 to 2010 were linked with the Induced Abortion Registry data from 1983 to 2007...
October 24, 2016: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/27770131/incarceration-of-the-gravid-uterus
#18
Kelsey L Shnaekel, Michael P Wendel, Nader Z Rabie, Everett F Magann
Objective: The aim of this review was to describe the risk factors, clinical and radiographic criteria, and management of this rare complication of pregnancy. Methods: A PubMed, Web of Science, and CINAHL search was undertaken with no limitations on the number of years searched. Results: There were 60 articles identified, with 53 articles being the basis of this review. Multiple risk factors have been suggested in the literature including retroverted uterus in the first trimester, deep sacral concavity with an overlying sacral promontory, endometriosis, previous abdominal or pelvic surgery, pelvic or uterine adhesions, ovarian cysts, leiomyomas, multifetal gestation, uterine anomalies, uterine prolapse, and uterine incarceration in a prior pregnancy...
October 2016: Obstetrical & Gynecological Survey
https://www.readbyqxmd.com/read/27769295/a-home-calendar-and-recall-method-of-last-menstrual-period-for-estimating-gestational-age-in-rural-bangladesh-a-validation-study
#19
Alison D Gernand, Rina Rani Paul, Barkat Ullah, Muhammad A Taher, Frank R Witter, Lee Wu, Alain B Labrique, Keith P West, Parul Christian
BACKGROUND: The best method of gestational age assessment is by ultrasound in the first trimester; however, this method is impractical in large field trials in rural areas. Our objective was to assess the validity of gestational age estimated from prospectively collected date of last menstrual period (LMP) using crown-rump length (CRL) measured in early pregnancy by ultrasound. METHODS: As part of a large, cluster-randomized, controlled trial in rural Bangladesh, we collected dates of LMP by recall and as marked on a calendar every 5 weeks in women likely to become pregnant...
October 21, 2016: Journal of Health, Population, and Nutrition
https://www.readbyqxmd.com/read/27766742/intracranial-translucency-assessment-at-first-trimester-nuchal-translucency-ultrasound
#20
Annah Lane, Ling Lee, Donna Traves, Andreas Lee
INTRODUCTION: The antenatal diagnosis of open spina bifida (OSB), a neural tube defect, is predominantly made at the second trimester morphology scan by ultrasound detection of structural abnormalities resulting from the associated Chiari II malformation. Evidence has emerged suggesting that these structural abnormalities can be detected earlier, by examination of the posterior fossa as part of the first trimester nuchal translucency scan. In particular, absence of the intra-cranial translucency (IT) of the fourth ventricle has shown promise as a diagnostic marker of OSB, although the sensitivity and specificity of this finding varies widely in the literature...
October 21, 2016: Journal of Medical Imaging and Radiation Oncology
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