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Perfusion CT

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https://www.readbyqxmd.com/read/29330589/impact-of-valve-less-vs-standard-insufflation-on-pneumoperitoneum-volume-inflammation-and-peritoneal-physiology-in-a-laparoscopic-sigmoid-resection-experimental-model
#1
Michele Diana, Eric Noll, Andras Legnèr, Seong-Ho Kong, Yu-Yin Liu, Luigi Schiraldi, Francesco Marchegiani, Jordan Bano, Bernard Geny, Anne-Laure Charles, Bernard Dallemagne, Véronique Lindner, Didier Mutter, Pierre Diemunsch, Jacques Marescaux
BACKGROUND: Standard insufflators compensate for intra-abdominal pressure variations with pressure spikes. Our aim was to evaluate the impact of a stable, low-pressure pneumoperitoneum induced by a valve-less insufflator, on working space, hemodynamics, inflammation, and peritoneal physiology, in a model of laparoscopic sigmoid resection. MATERIALS AND METHODS: Twelve pigs (47 ± 3.3 kg) were equipped for invasive hemodynamic monitoring and randomly assigned to Standard (n = 6) vs...
January 12, 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/29324936/the-impact-of-lung-perfusion-scintigraphy-in-the-emergency-management-of-patients-with-suspected-pulmonary-embolism
#2
Cristina Ferrari, Alessandra Cimino, Giacomo Bianco, Francesca Iuele, Alessandra Di Palo, Margherita Fanelli, Artor Niccoli-Asabella, Giuseppe Rubini
OBJECTIVE: Pulmonary Embolism (PE) is an emergency condition that requires immediate treatment. As the symptoms and the risk factors are nonspecific, PE differential diagnosis is often required. Even if angio-CT is considered the gold standard for PE diagnosis, the frequent allergic condition and/or chronic renal failure of patients make, in most cases, not possible the use of contrast enhancement in emergency with even more increasing use of Lung Perfusion Scintigraphy (LPS), as a simple and fast examination with no preparation/contraindication...
September 2017: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/29320864/diagnostic-performance-of-static-single-scan-stress-perfusion-cardiac-computed-tomography-in-detecting-hemodynamically-significant-coronary-artery-stenosis-a-comparison-with-combined-invasive-coronary-angiography-and-cardiovascular-magnetic-resonance-myocardial
#3
Inyoung Song, Jeong Geun Yi, Jeong Hee Park, Mi Young Kim, Je Kyoun Shin, Sung Min Ko
Background Non-invasive anatomical and physiological evaluations of coronary artery disease (CAD) may be obtained with static single-scan stress perfusion cardiac computed tomography (SSPCT). Purpose To determine the diagnostic performance of static SSPCT for identifying hemodynamically significant CAD. Material and Methods This prospective study included 29 patients with suspected or known CAD who underwent static SSPCT, cardiovascular magnetic resonance myocardial perfusion imaging (CMR-MPI), and invasive coronary angiography (ICA)...
January 1, 2018: Acta Radiologica
https://www.readbyqxmd.com/read/29316173/usefulness-of-fluorescence-vascular-imaging-for-evaluating-splenic-perfusion
#4
Yota Kawasaki, Kosei Maemura, Hiroshi Kurahara, Yuko Mataki, Satoshi Iino, Masahiko Sakoda, Hiroyuki Shinchi, Shoji Natsugoe
BACKGROUND: The aim of this study was to confirm whether intraoperative fluorescence vascular imaging using indocyanine green (FVI-ICG) is useful for evaluating splenic perfusion after spleen-preserving distal pancreatectomy (SPDP) performed with the Warshaw technique (SPDP-W). METHODS: We evaluated the blood perfusion of the spleen with an intraoperative FVI-ICG system after SPDP-W. All of the patients underwent dynamic computed tomography (CT) scans at one post-operative week and one post-operative month to evaluate the post-operative blood perfusion of the spleen...
January 8, 2018: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/29301706/an-experimental-study-and-finite-element-modeling-of-head-and-neck-cooling-for-brain-hypothermia
#5
Hui Li, Roland K Chen, Yong Tang, William Meurer, Albert J Shih
Reducing brain temperature by head and neck cooling is likely to be the protective treatment for humans when subjects to sudden cardiac arrest. This study develops the experimental validation model and finite element modeling (FEM) to study the head and neck cooling separately, which can induce therapeutic hypothermia focused on the brain. Anatomically accurate geometries based on CT images of the skull and carotid artery are utilized to find the 3D geometry for FEM to analyze the temperature distributions and 3D-printing to build the physical model for experiment...
January 2018: Journal of Thermal Biology
https://www.readbyqxmd.com/read/29297607/signal-enhancement-ratio-imaging-of-the-lung-parenchyma-with-ultra-fast-steady-state-free-precession-mri-at-1-5t
#6
Orso Pusterla, Gregor Sommer, Francesco Santini, Mark Wiese, Didier Lardinois, Michael Tamm, Jens Bremerich, Grzegorz Bauman, Oliver Bieri
BACKGROUND: Lung perfusion MRI after i.v. gadolinium (Gd) contrast administration is commonly based on spoiled gradient-echo acquisitions, such as volume-interpolated breath-hold examinations (VIBE), suffering from low signal-to-noise in the parenchyma. PURPOSE: To investigate the lung signal enhancement ratio (SER) with ultra-fast steady-state free precession (ufSSFP) after Gd-administration. STUDY TYPE: Retrospective. SUBJECTS: Ten subjects with healthy lungs; nine patients with pulmonary diseases (chronic obstructive pulmonary disease [COPD], lung cancer, pulmonary fibrosis, lung contusion)...
January 3, 2018: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/29285726/myocardial-perfusion-in-patients-with-non-ischaemic-systolic-heart-failure-and-type-2-diabetes-a-cross-sectional-study-using-rubidium-82-pet-ct
#7
Christina Byrne, Philip Hasbak, Andreas Kjaer, Jens Jakob Thune, Lars Køber
Both patients with non-ischaemic systolic heart failure and patients with type 2 diabetes (T2DM) often have reduced myocardial blood flow without significant coronary atherosclerosis. However, the mechanisms are not fully understood. The aim of this study was to investigate whether perfusion is reduced additionally when the 2 are combined. In a cross-sectional study, we scanned patients with non-ischaemic systolic heart failure with and without T2DM using Rubidium-82 positron emission tomography/computed tomography at rest and adenosine-induced stress, thereby obtaining the myocardial flow reserve (myocardial flow reserve (MFR) = stress flow/rest flow) as a measure of the myocardial vasomotor function; 28 patients with T2DM and 123 without T2DM were included...
December 28, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/29285410/the-clinical-examination-in-the-patient-with-subarachnoid-hemorrhage-is-still-the-most-reliable-parameter-for-predicting-pathophysiological-changes
#8
Athanasios K Petridis, Kerim Beseoglu, Hans J Steiger
Background: Macrovasospasms and delayed cerebral injury are factors which correlate with high morbidity in patients suffering a subarachnoid hemorrhage. Transcranial Doppler (TCD) ultrasonography and perfusion computed tomography (PCT) are diagnostic tools used to diagnose such pathologies. However, TCD is not very reliable and PCT exposes patients to radiation and cannot be performed daily. Case Description: We present the case of a 47-year-old female with subarachnoid hemorrhage caused by rupture of an intracranial aneurysm...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/29282332/collateral-response-modulates-the-time-penumbra-relationship-in-proximal-arterial-occlusions
#9
Smriti Agarwal, Andrew Bivard, Elizabeth Warburton, Mark Parsons, Christopher Levi
OBJECTIVE: While clinical benefit from thrombolysis decreases with increase in time from stroke onset, the relationship of acute physiologic tissue compartments and collateral response to stroke onset time remains unclear. METHODS: We studied consecutive patients with proximal arterial occlusions (n = 355) with whole-brain perfusion CT with CT angiography within 6 hours of stroke onset. Penumbra and core were defined using voxel-based thresholds. Tissue mismatch was defined as the ratio of penumbra to core...
December 27, 2017: Neurology
https://www.readbyqxmd.com/read/29279169/hepatocellular-carcinoma-treated-with-sorafenib-arterial-tumor-perfusion-in-dynamic-contrast-enhanced-ct-as-early-imaging-biomarkers-for-survival
#10
Yuko Nakamura, Tomokazu Kawaoka, Toru Higaki, Wataru Fukumoto, Yukiko Honda, Makoto Iida, Chikako Fujioka, Masao Kiguchi, Hiroshi Aikata, Kazuaki Chayama, Kazuo Awai
OBJECTIVES: To investigate whether hepatic perfusion CT yields early imaging biomarkers predictive of the prognosis of hepatocellular carcinoma (HCC) patients treated with sorafenib. METHODS: We evaluated 36 HCC patients who underwent hepatic perfusion CT before- and one week after sorafenib therapy. We measured arterial and portal perfusion in the hepatic tumor and liver parenchyma [(AP)(PP)tumor], [(AP)(PP)liver]. The perfusion ratio was calculated by dividing the post- by the pre-sorafenib value...
January 2018: European Journal of Radiology
https://www.readbyqxmd.com/read/29278545/treatment-effect-of-balloon-pulmonary-angioplasty-in-chronic-thromboembolic-pulmonary-hypertension-quantified-by-automatic-comparative-imaging-in-computed-tomography-pulmonary-angiography
#11
Zhiwei Zhai, Hideki Ota, Marius Staring, Jan Stolk, Koichiro Sugimura, Kei Takase, Berend C Stoel
OBJECTIVES: Balloon pulmonary angioplasty (BPA) in patients with inoperable chronic thromboembolic pulmonary hypertension (CTEPH) can have variable outcomes. To gain more insight into this variation, we designed a method for visualizing and quantifying changes in pulmonary perfusion by automatically comparing computed tomography (CT) pulmonary angiography before and after BPA treatment. We validated these quantifications of perfusion changes against hemodynamic changes measured with right-sided heart catheterization...
December 22, 2017: Investigative Radiology
https://www.readbyqxmd.com/read/29274600/evidence-of-intimal-tear-in-type-a-intramural-hematoma-of-the-aorta-a-case-series
#12
Gianfranco Filippone, Giovanni Caruana, Claudia Calia, Violetta Moscaritolo, Vincenzo Argano
INTRODUCTION: Aortic intramural hematoma (IMH) is described as "dissection without intimal tear" due to rupture of vasa vasorum, which results in bleeding within the tunica media in the absence of intimal disruption or blood flow communication. The aim of our study is to validate perioperative evidence of intimal entry tear in patients with IMH and to suggest that this entity may represent a part of a disease and not a separate disease. PRESENTATION OF CASES: We report two patients admitted to our institution with sudden onset thoracic pain...
December 12, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29273698/effective-dose-in-nuclear-medicine-studies-and-spect-ct-dosimetry-survey-across-quebec-province
#13
Mathieu Charest, Chantal Asselin
Purpose: The aims of the current survey were to draw a portrait of the delivered dose in nuclear medicine selected studies and to assess the degree of changes since an earlier survey performed in 2010. Methods: Each surveyed site had to fill two forms about the administered activity in selected nuclear medicine studies and about the CT parameters used in SPECT/CT imaging, if available. The administered activities were converted into effective doses using the most recent conversion factors. Diagnostic reference levels were computed for each imaging procedure, in order to provide a benchmark for comparison...
December 22, 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/29273695/cardiac-displacement-during-13n-ammonia-myocardial-perfusion-pet-ct-comparison-between-adenosine-and-regadenoson-induced-stress
#14
Elise Vleeming, Sergiy Lazarenko, Friso van der Zant, Xiao-Bo Pan, Jerome Declerck, Maurits Wondergem, Remco Knol
PURPOSE: In this study, differences are investigated in cardiac displacement during adenosine stress versus regadenoson stress in 13N-Ammonia(13NH3) MP PET/CT scans. METHODS: A total of 61 MP PET/CTs were acquired using either adenosine (n=30) or regadenoson (n=31) as a stressor. For both groups, cardiac displacement during rest and stress was measured three-dimensionally, relative to either a fixed reference frame or the previous frame, in each 1-minute frame of a list-mode PET acquisition of 25 minutes...
December 22, 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/29273536/variability-of-stroke-patients-meeting-endovascular-stroke-trial-criteria-in-a-non-clinical-trial-setting
#15
Jennifer E Fugate, Waleed Brinjikji, Harry Cloft, David F Kallmes, Alejandro A Rabinstein
BACKGROUND: Five randomized trials proving the efficacy and safety of mechanical embolectomy for ischemic stroke within 8hours used differing radiological methods to select patients. We aimed to evaluate the proportion of patients in clinical practice that would meet radiological criteria for inclusion in these trials. METHODS: Retrospective study of ischemic stroke patients at a large academic medical center who were considered for endovascular stroke therapy based on confirmed intracranial large vessel occlusion from April 2010-November 2014...
December 19, 2017: Journal of Neuroradiology. Journal de Neuroradiologie
https://www.readbyqxmd.com/read/29259124/referral-facility-ct-perfusion-prior-to-inter-facility-transfer-in-patients-undergoing-mechanical-thrombectomy
#16
Amin Aghaebrahim, Eric Sauvageau, Pedro Aguilar-Salinas, Gustavo Cortez, Roberta Santos, Ricardo A Hanel
BACKGROUND AND PURPOSE: The use of CT perfusion (CTP) imaging at a referring hospital is feasible and may shorten the door to puncture time for patients with acute ischemic stroke. METHODS: We conducted a single center retrospective review of a prospectively maintained database of consecutive ischemic stroke patients transferred to our center for consideration of endovascular therapy. Patients were divided into two groups. Group 1 consisted of patients transferred from facilities where CTP (using automated RAPID software) was routinely performed and group 2 consisted of patients transferred from facilities that did not perform perfusion imaging...
December 19, 2017: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/29250564/measuring-arterial-wall-perfusion-using-photon-counting-computed-tomography-ct-improving-ct-number-accuracy-of-artery-wall-using-image-deconvolution
#17
Kishore Rajendran, Shuai Leng, Steven M Jorgensen, Jill L Anderson, Ahmed F Halaweish, Dilbar Abdurakhimova, Erik L Ritman, Cynthia H McCollough
Changes in arterial wall perfusion mark the onset of atherosclerosis. A characteristic change is the increased spatial density of vasa vasorum (VV), the microvessels in the arterial walls. Measuring this increased VV (IVV) density using contrast-enhanced computed tomography (CT) has had limited success due to blooming effects from contrast media. If the system point-spread function (PSF) is known, then the blooming effect can be modeled as a convolution between the true signal and the PSF. We report the application of image deconvolution to improve the CT number accuracy in the arterial wall of a phantom and in a porcine model of IVV density, both scanned using a whole-body research photon-counting CT scanner...
October 2017: Journal of Medical Imaging
https://www.readbyqxmd.com/read/29249450/perfusion-defects-in-pulmonary-perfusion-iodine-maps-causes-and-semiology
#18
A Bustos Fiore, M González Vázquez, C Trinidad López, D Mera Fernández, M Costas Álvarez
OBJECTIVE: to describe the usefulness of dual-energy CT for obtaining pulmonary perfusion maps to provide morphological and functional information in patients with pulmonary embolisms. To review the semiology of perfusion defects due to pulmonary embolism so they can be differentiated from perfusion defects due to other causes: alterations outside the range used in the iodine map caused by other diseases of the lung parenchyma or artifacts. CONCLUSION: CT angiography of the pulmonary arteries is the technique of choice for the diagnosis of pulmonary embolisms...
December 14, 2017: Radiología
https://www.readbyqxmd.com/read/29249347/enhancement-of-dynamic-myocardial-perfusion-pet-images-based-on-low-rank-plus-sparse-decomposition
#19
Lijun Lu, Xiaomian Ma, Hassan Mohy-Ud-Din, Jianhua Ma, Qianjin Feng, Arman Rahmim, Wufan Chen
BACKGROUND AND OBJECTIVE: The absolute quantification of dynamic myocardial perfusion (MP) PET imaging is challenged by the limited spatial resolution of individual frame images due to division of the data into shorter frames. This study aims to develop a method for restoration and enhancement of dynamic PET images. METHODS: We propose that the image restoration model should be based on multiple constraints rather than a single constraint, given the fact that the image characteristic is hardly described by a single constraint alone...
February 2018: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/29248657/comprehensive-cardiac-ct-with-myocardial-perfusion-imaging-versus-functional-testing-in-suspected-coronary-artery-disease-the-multicenter-randomized-crescent-ii-trial
#20
Marisa Lubbers, Adriaan Coenen, Marcel Kofflard, Tobias Bruning, Bas Kietselaer, Tjebbe Galema, Marc Kock, Andre Niezen, Marco Das, Marco van Gent, Ewout-Jan van den Bos, Leon van Woerkens, Paul Musters, Suze Kooij, Fay Nous, Ricardo Budde, Miriam Hunink, Koen Nieman
OBJECTIVES: This study sought to assess the effectiveness, efficiency, and safety of a tiered, comprehensive cardiac computed tomography (CT) protocol in comparison with functional testing. BACKGROUND: Although CT angiography accurately rules out coronary artery disease (CAD), incorporation of CT myocardial perfusion imaging as part of a tiered diagnostic approach could improve the clinical value and efficiency of cardiac CT in the diagnostic work-up of patients with angina pectoris...
December 8, 2017: JACC. Cardiovascular Imaging
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