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https://www.readbyqxmd.com/read/29168576/clinical-value-of-peripheral-blood-microrna-detection-in-evaluation-of-sox-regimen-as-neoadjuvant-chemotherapy-for-gastric-cancer
#1
Bibo Tan, Yong Li, Yan Di, Liqiao Fan, Qun Zhao, Qingwei Liu, Dong Wang, Nan Jia
BACKGROUND: Neoadjuvant chemotherapy has been widely applied in treating advanced gastric cancer (GC). However, little research has been conducted on evaluating the effect of neoadjuvant chemotherapy. Purpose of this study was to evaluate the effect of SOX regimen as neoadjuvant chemotherapy by detecting some microRNAs. METHODS: Total 120 GC patients who had received neoadjuvant chemotherapy (SOX regimen) were recruited with 100 healthy participants as control contemporarily...
November 23, 2017: Journal of Clinical Laboratory Analysis
https://www.readbyqxmd.com/read/29168565/growth-rates-of-pulmonary-metastases-after-liver-transplantation-for-unresectable-colorectal-liver-metastases
#2
H Grut, S Solberg, T Seierstad, M E Revheim, T S Egge, S G Larsen, P D Line, S Dueland
BACKGROUND: The previously reported SECA study demonstrated a dramatic 5-year survival improvement in patients with unresectable colorectal liver metastases (CLM) treated with liver transplantation (LT) compared with chemotherapy. The objective of this study was to assess whether immunosuppressive therapy accelerates the growth of pulmonary metastases in patients transplanted for unresectable CLM. METHODS: Chest CT scans from 11 patients in the SECA study resected for 18 pulmonary metastases were reviewed retrospectively...
November 23, 2017: British Journal of Surgery
https://www.readbyqxmd.com/read/29167928/pulmonary-contusions-after-blunt-chest-trauma-clinical-significance-and-evaluation-of-patient-management
#3
Z Požgain, D Kristek, I Lovrić, G Kondža, M Jelavić, J Kocur, M Danilović
INTRODUCTION: A pulmonary contusion is an entity defined as alveolar haemorrhage and pulmonary parenchymal destruction after blunt chest trauma. According to the literature, most pulmonary contusions can only be seen on a chest CT. The aim of this study was to evaluate the patients with pulmonary contusions, as well as their management, considering diagnostic and therapeutic options related to their outcomes, since we assumed, based on everyday clinical practice, that an 'overdiagnosing' and 'overtreatment' attitude towards this injury could be present...
November 22, 2017: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://www.readbyqxmd.com/read/29167754/a-mass-that-has-no-ebus-echo
#4
Matthew K Rosenblum, Sue X Wang, Eric J Seeley
We report findings for a patient that underwent endobronchial ultrasound (EBUS) guided transbronchial needle aspiration (TBNA) for diagnostic purposes after an abnormal chest CT. The patient initially presented with cough and shortness of breath. Chest CT revealed a 6 cm soft tissue mass with mildly enlarged right hilar lymph nodes (LNs) and a small right sided pleural effusion. Based on these radiologic findings, the patient underwent an EBUS guided FNA of the mass. To our surprise, the mass was hypoechoic by EBUS and on aspiration, the syringe filled with yellow fluid...
2018: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/29167714/micro-ct-study-of-the-root-canal-anatomy-of-maxillary-canines
#5
Hugo Plascencia, Álvaro Cruz, Claudia-Azucena Palafox-Sánchez, Mariana Díaz, Claudia López, Clovis-Monteiro Bramante, Bertram I Moldauer, Ronald Ordinola-Zapata
Background: This study aimed to describe the anatomy of maxillary canines from a Western Mexican sub-population using micro-computed tomography (micro-CT). Material and Methods: Maxillary canines (n=32) were scanned at 19.6µm voxel resolution. Number and location of canals, the distance between the cemento-enamel junction and apex, occurrence of accessory and lateral canals, presence of oval canals, number of foraminas as well as two- (area, perimeter, roundness, aspect ratio, major and minor diameters) and three-dimensional (volume, surface area, and SMI) analysis were performed...
October 2017: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/29167068/three-dimensional-morphology-of-lunate-surface-in-hip-dysplasia-theoretical-implications-for-periacetabular-osteotomy
#6
Meng Xu, Yanbing Wang, Lei Zhong, Yang Song, Jianlin Xiao, Yu Sun, Wei Li, Zhe Zhu, Xin Zhao, Jincheng Wang
BACKGROUND: The objective of this study was to evaluate three-dimensional morphology of acetabular lunate surface in patients with dysplastic hip using three-dimensional computed tomography (CT), and to compare the lunate surface morphology between the normal and dysplastic hips. METHODS: Sixty seven dysplastic hips in symptomatic patients and 61 normal hips in healthy volunteers who underwent three-dimensional CT scanning were included in this study. The size and shape of the lunate surface was measured with a fully automated imaging technique using Mimics16...
November 19, 2017: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/29166493/dystrophic-calcification-of-maxillary-sinus-in-pediatric-patients-with-liver-transplantation-and-pigmentation-of-dental-organ
#7
Adriana Furtado de Macedo, Claudio Costa, Regina Helena Guedes da Motta Mattar, Ramiro Anthero de Azevedo
OBJECTIVE: To report a case of severe dystrophic calcification in maxillary sinus of a child with liver transplantation and dental organs pigmented by hyperbilirubinemia. CASE DESCRIPTION: female patient, 12 years old, with liver transplantation performed at the age of 7 due to extrahepatic biliary atresia (EHBA). The patient was receiving the immunosuppressant tacrolimus (2 mg daily). Intraoral clinical exam showed tooth green pigmentation by bilirubin. Cone-beam volumetric computed tomography (CT) was performed to verify radiographic density of pigmented dental elements...
November 17, 2017: Revista Paulista de Pediatria: Orgão Oficial da Sociedade de Pediatria de São Paulo
https://www.readbyqxmd.com/read/29166425/anatomy-of-the-sphenopalatine-artery-and-its-implications-for-transnasal-neurosurgery
#8
M Eordogh, A Grimm, I Gawish, L Patonay, R Reisch, H R Briner, G Baksa
BACKGROUND: The knowledge of sinonasal vasculature is inevitable in transnasal neurosurgery. We performed an anatomical study on the sphenopalatine artery from the perspective of skull base procedures. METHODOLOGY: To analyse the anatomical landmarks of the sphenopalatine artery, arterial skull corrosion casts (26 head halves) underwent endoscopic transnasal phantom surgery. Furthermore, we performed microsurgical dissection on formaldehyde-fixated cadavers with arterial perfusion (14 head halves) as well as studied Cone Beam CT-scans of anonymised patients and cadavers (115 head sides)...
November 22, 2017: Rhinology
https://www.readbyqxmd.com/read/29166335/multiple-hypermetabolic-subcutaneous-lesions-from-hidradenitis-suppurativa-mimicking-metastases-on-18f-fdg-pet-ct
#9
Philip Asamoah, Daniel J Wale, Benjamin L Viglianti, Ka Kit Wong, Milton Gross
Hidradenitis suppurativa is an inflammatory disease associated with subcutaneous nodules/abscesses that occur commonly in the axillary, inguinal, and perineal regions. We describe a case of a 64-year-old man presenting for F-FDG PET/CT for staging of a left vocal cord squamous cell carcinoma. The scan showed uptake in the left vocal cord malignancy and multiple hypermetabolic subcutaneous foci in the right axilla, right buttocks, and scalp in known locations of skin lesions related to hidradenitis suppurativa...
November 22, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/29166334/gastrointestinal-stromal-tumor-of-the-prostate-staging-and-evaluation-of-response-to-therapy-with-18f-fdg-pet-ct
#10
Yazan Z Alabed
A 49-year-old man presented for routine general physical examination was found with an enlarged prostate gland without associated symptoms. Ultrasound followed by computed tomography (CT) of abdomen and pelvis confirmed a markedly enlarged heterogeneous prostate gland. Subsequently, a staging flourine-18 fluorodeoxyglucose (F-FDG) positron emission tomography (PET/CT) scan revealed intensely FDG-avid mass involving the prostate, which was biopsied as gastrointestinal stromal tumor (GIST). The patient was treated with imatinib and a follow-up PET/CT scan showed complete metabolic response...
November 22, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/29166327/68ga-prostate-specific-membrane-antigen-uptake-in-gastrointestinal-stromal-tumor
#11
Tom Laurens, Fred Witjes, Marcel Janssen, Uta Flucke, Martin Gottardt
A 62-year-old man with recently diagnosed prostatic adenocarcinoma was referred for a whole-body Ga-prostate-specific membrane antigen (PSMA) PET/CT scan for staging. Although the scan did not reveal metastatic disease, it did reveal a PSMA-avid lesion in the upper abdomen located between the liver and the stomach. Histopathologic examination demonstrated a gastrointestinal stromal tumor. The lesion demonstrated increased uptake in the margins of the tumor with a central photopenic area, which we consider to be the typical pattern on PSMA images of a gastrointestinal stromal tumor, based on theoretical PSMA distribution in such a tumor and other reported cases...
November 22, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/29165437/endolymphatic-sac-tumour-in-von-hippel-lindau-disease-management-strategies
#12
E Zanoletti, L Girasoli, D Borsetto, G Opocher, A Mazzoni, A Martini
Endolymphatic sac tumour (ELST) is infrequent, as emerges from small series reported in the literature. It is a slow-growing malignancy with local aggressiveness and a low risk of distant metastases. It is often misdiagnosed because of the late onset of symptoms and difficulty in obtaining a biopsy. Its frequency is higher in von Hippel-Lindau (VHL) disease (a genetic systemic syndrome involving multiple tumours), with a prevalence of around 25%. The diagnosis is based on radiology, with specific patterns on contrast-enhanced MRI and typical petrous bone erosion on bone CT scan...
October 2017: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/29165324/in-vivo-evaluation-of-modified-silk-fibroin-scaffolds-with-a-mimicked-microenvironment-of-fibronectin-decellularized-pulp-tissue-for-maxillofacial-surgery
#13
Thanh H Thai, Thongchai Nuntanaranont, Suttatip Kamolmatyakul, Jirut Meesane
This study aimed to carry out in vivo testing of the formation of new bone by modified silk fibroin scaffolds with a mimicked microenvironment of fibronectin/decellularized pulp in bone defects. Silk fibroin scaffolds were fabricated into three-dimensional scaffolds before being coated with fibronectin/decellularized pulp. The coated scaffolds were implanted into rabbits. Twenty-four bicortical calvarial defects in 12 rabbits were divided randomly into two groups: non-coated and coated silk fibroin scaffolds...
November 22, 2017: Biomedical Materials
https://www.readbyqxmd.com/read/29165319/comparison-of-forward-and-back-projection-in-vivo-epid-dosimetry-for-vmat-treatment-of-the-prostate
#14
James L Bedford, Ian Maddock Hanson, Vibeke N Hansen
In the forward-projection method of portal dosimetry for volumetric modulated arc therapy (VMAT), the integrated signal at the electronic portal imaging device (EPID) is predicted at the time of treatment planning, against which the measured integrated image is compared. In the back-projection method, the measured signal at each gantry angle is back-projected through the patient CT scan to give a measure of total dose to the patient. This study aims to investigate the practical agreement between the two types of EPID dosimetry for prostate radiotherapy...
November 22, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/29164628/technical-note-response-time-evolution-of-xr-qa2-gafchromic-tm-film-models
#15
Saad Aldelaijan, Nada Tomic, Pavlos Papaconstadopoulos, James Schneider, Jan Seuntjens, Shelley Shih, David Lewis, Slobodan Devic
PURPOSE: To evaluate the response of the newest XR-QA2 GafChromic(™) film model in terms of post-exposure signal growth and energy response in comparison with the older XR-QA (Version 2) model. METHODS: Pieces of film were irradiated to air kerma in air values up to 12 cGy with several beam qualities (5.3-8.25 mm Al) commonly used for CT scanning. Film response was scored in terms of net reflectance from scanned film images at various points in time post-irradiation ranging from 1 to 7 days and 5 months post exposure...
November 22, 2017: Medical Physics
https://www.readbyqxmd.com/read/29164583/application-of-dynamic-ct-to-identify-lung-cancer-pulmonary-tuberculosis-and-pulmonary-inflammatory-pseudotumor
#16
X-L Wang, W Shan
OBJECTIVE: To determine the value of dynamic enhanced computed tomography (CT) scanning in diagnosing lung cancer, pulmonary tuberculosis, and pulmonary inflammatory pseudotumor. PATIENTS AND METHODS: We recruited 30 patients with pulmonary tuberculoma, 38 with lung cancer, and 16 with pulmonary inflammatory pseudotumor. All patients received CT scanning, dynamic enhanced CT scanning for 20, 30, 45, 60, 75, 90, and 120 s, and scanning for 3, 5, 8, 12, and 15 min...
November 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29164450/accuracy-of-early-ct-findings-for-predicting-disease-course-in-patients-with-acute-pancreatitis
#17
Onur Taydas, Emre Unal, Ali Devrim Karaosmanoglu, Mehmet Ruhi Onur, Erhan Akpinar
PURPOSE: To investigate whether computed tomography (CT)-based scoring systems obtained within 72 h of symptoms onset can predict disease course in acute pancreatitis. METHODS: Between October 2007 and December 2015, 189 patients (age range 21-93 years) who underwent abdominopelvic CT for the diagnosis of acute pancreatitis were included in the study. Balthazar grade and original and modified versions of CT severity index (CTSI) measurements were carried out for each patient...
November 21, 2017: Japanese Journal of Radiology
https://www.readbyqxmd.com/read/29164382/ct-texture-features-of-liver-parenchyma-for-predicting-development-of-metastatic-disease-and-overall-survival-in-patients-with-colorectal-cancer
#18
Scott J Lee, Ryan Zea, David H Kim, Meghan G Lubner, Dustin A Deming, Perry J Pickhardt
OBJECTIVES: To determine if identifiable hepatic textural features are present at abdominal CT in patients with colorectal cancer (CRC) prior to the development of CT-detectable hepatic metastases. METHODS: Four filtration-histogram texture features (standard deviation, skewness, entropy and kurtosis) were extracted from the liver parenchyma on portal venous phase CT images at staging and post-treatment surveillance. Surveillance scans corresponded to the last scan prior to the development of CT-detectable CRC liver metastases in 29 patients (median time interval, 6 months), and these were compared with interval-matched surveillance scans in 60 CRC patients who did not develop liver metastases...
November 21, 2017: European Radiology
https://www.readbyqxmd.com/read/29164301/changes-in-multimodality-functional-imaging-parameters-early-during-chemoradiation-predict-treatment-response-in-patients-with-locally-advanced-head-and-neck-cancer
#19
Kee H Wong, Rafal Panek, Alex Dunlop, Dualta Mcquaid, Angela Riddell, Liam C Welsh, Iain Murray, Dow-Mu Koh, Martin O Leach, Shreerang A Bhide, Christopher M Nutting, Wim J Oyen, Kevin J Harrington, Kate L Newbold
OBJECTIVE: To assess the optimal timing and predictive value of early intra-treatment changes in multimodality functional and molecular imaging (FMI) parameters as biomarkers for clinical remission in patients receiving chemoradiation for head and neck squamous cell carcinoma (HNSCC). METHODS: Thirty-five patients with stage III-IVb (AJCC 7th edition) HNSCC prospectively underwent (18)F-FDG-PET/CT, and diffusion-weighted (DW), dynamic contrast-enhanced (DCE) and susceptibility-weighted MRI at baseline, week 1 and week 2 of chemoradiation...
November 21, 2017: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/29164174/early-life-pseudomonas-aeruginosa-infection-in-cystic-fibrosis-and-lung-disease-progression
#20
Argyri Petrocheilou, Maria Papagrigoriou-Theodoridou, Athanasios Michos, Stavros-Eleftherios Doudounakis, Ioanna Loukou, Athanasios Kaditis
Lung disease in cystic fibrosis (CF) starts early, with studies identifying abnormalities on chest computed tomography (CT) scan even in infancy. In this retrospective study, abnormal chest CT was the main outcome; body mass index (BMI) z score and forced expiratory volume percent predicted (FEV1%) predicted at age 6 to 7 years were secondary outcomes. Pseudomonas aeruginosa infection prior to 12 months of age was the main explanatory variable. There was no association between early P aeruginosa infection and abnormal CT after adjustment for CFTR (cystic fibrosis transmembrane conductance regulator) functional mutation class, gender, and other pathogens (odds ratio = 0...
2017: Global Pediatric Health
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