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https://www.readbyqxmd.com/read/28072804/multidisciplinary-care-of-unruptured-brain-arteriovenous-malformations-to-improve-symptomatic-headache-and-the-onset-progression-and-outcomes-of-unruptured-brain-arteriovenous-malformations
#1
Ling-Feng Lai, Min Chen, Jia-Xiang Chen, Kuang Zheng, Xu-Ying He, Xi-Feng Li, Xin Zhang, Jian Yin, Qiu-Jing Wang, Tuan-Ming Zou, Chuan-Zhi Duan
BACKGROUND: Symptomatic headaches attributed to unruptured brain arteriovenous malformations (ubAVMs) are very common and affect patients' quality life, but multidisciplinary care of ubAVMs to improve symptomatic headache remains unclear. OBJECTIVE: The objective is to identify the features of symptomatic headaches, and to obtain headache outcomes following multidisciplinary care of ubAVMs, as well as provide background on the natural history of ubAVMs. STUDY DESIGN: The features of symptomatic headaches and headache outcomes were analyzed in a large cohort of cases after multidisciplinary care of ubAVMs...
January 2017: Pain Physician
https://www.readbyqxmd.com/read/28064338/-unknown-title
#2
V J Lund, Y Darby, J Rimmer, M Amin, S Husain
INTRODUCTION: Hereditary haemorrhagic telangiectasia (HHT) is an autosomal dominant vascular disease characterized by recurrent epistaxis, mucocutaneous telangiectasia and visceral arteriovenous malformations. The nosebleeds can be life-threatening and in these circumstances, radical treatment is required. METHODS: Since 1994, closure of the nose has been undertaken to prevent severe nasal bleeding in patients meeting specific selection criteria. Outcome data collected on this cohort pre- and post-operatively is available for analysis...
January 8, 2017: Rhinology
https://www.readbyqxmd.com/read/28057059/invasive-pneumococcal-disease-caused-by-mucoid-serotype-3-streptococcus-pneumoniae-a-case-report-and-literature-review
#3
Naomi Sugimoto, Yuka Yamagishi, Jun Hirai, Daisuke Sakanashi, Hiroyuki Suematsu, Naoya Nishiyama, Yusuke Koizumi, Hiroshige Mikamo
BACKGROUND: Among the different serotypes of Streptococcus pneumoniae, serotype 3 has received global attention. We report the fatal case of a 76-year-old Japanese man who had an invasive pneumococcal disease associated with pneumonia caused by serotype 3 S. pneumoniae. CASE PRESENTATION: The patient had a history of hypertension, laryngeal cancer, chronic obstructive pulmonary disease, and type 2 diabetes mellitus. Following a cerebral arteriovenous malformation hemorrhage, he underwent surgery to remove the hematoma and began rehabilitation...
January 4, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28054837/radiosurgery-alters-the-endothelial-surface-proteome-externalized-intracellular-molecules-as-potential-vascular-targets-in-irradiated-brain-arteriovenous-malformations
#4
Lucinda S McRobb, Vivienne S Lee, Margaret Simonian, Zhenjun Zhao, Santhosh George Thomas, Markus Wiedmann, Jude V Amal Raj, Michael Grace, Vaughan Moutrie, Matthew J McKay, Mark P Molloy, Marcus A Stoodley
Stereotactic radiosurgery (SRS) is an established treatment for brain arteriovenous malformations (AVMs) that drives blood vessel closure through cellular proliferation, thrombosis and fibrosis, but is limited by a delay to occlusion of 2-3 years and a maximum treatable size of 3 cm. In this current study we used SRS as a priming tool to elicit novel protein expression on the endothelium of irradiated AVM vessels, and these proteins were then targeted with prothrombotic conjugates to induce rapid thrombosis and vessel closure...
January 5, 2017: Radiation Research
https://www.readbyqxmd.com/read/28049610/application-of-fluorescein-sodium-videoangiography-in-surgery-for-spinal-arteriovenous-malformation
#5
Basant K Misra, Saurav K Samantray, Omkar N Churi
We present our recent experience with fluorescein sodium videoangiography (FLVA) in the intra-operative evaluation of a patient with conus medullaris arteriovenous malformation (AVM). To our knowledge this is the first report in the literature of use of FLVA in the surgery of spinal AVM. Intra-operative FLVA was done to identify an early filling vessel and to obliterate the site of fistulous connection. This was correlated and confirmed with simultaneous indocyanine green videoangiography (ICGVA). The conus and cauda equina roots could be appreciated and manipulated in relation to this fluorescence...
December 31, 2016: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28048781/su-f-t-141-proton-dose-validation-in-a-phantom-beyond-trufill-n-bca-embolization-glue
#6
A Mandapaka, A Ghebremedhin, B Patyal, Loma Linda
PURPOSE: To validate the treatment planning system predicted proton dose beyond a heterogeneity (n-BCA glue) by making a measurement in a custom acrylic phantom. METHODS: A custom cubic acrylic phantom was designed for this experiment. A container was designed to fit in the phantom. This container was filled with TRUFILL™ n-Butyl Cyanoacrylate(n-BCA) glue. When the container was placed in the phantom, its center was at a distance of 7.4cm from the entrance. This depth allows us to make measurements around the center of modulation of a 126 MeV proton beam with a 3cm spread-out-Bragg peak...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047666/su-f-t-651-dosimetric-impact-of-patient-setup-rotational-errors-for-multi-staged-large-avm-gammaknife-radiosurgery
#7
C Ding, B Hrycushko, R Abdulrahman, L Whitworth, S Jiang, R Timmerman
PURPOSE: Multi-staged large AVM (>10 cm3 or diameter > 3 cm) Gammaknife radiosurgery requires setting up the patient based on a pre-treatment plan over several fractions. Residual rotational errors cannot be compensated by translational repositioning of the patient and may adversely impact the dose distribution on the total AVM target. This study evaluates the effect of residual rotational setup error. METHODS: The total AVM target was contoured and split into several small sub-targets...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28042014/microsurgical-outcome-of-unruptured-brain-arteriovenous-malformations-a-single-center-experience
#8
Xianzeng Tong, Jun Wu, Yong Cao, Yuanli Zhao, Shuo Wang, Jizong Zhao
OBJECTIVE: We aimed to describe our single-center experience in treating unruptured brain arteriovenous malformations (uBAVMs) with microsurgical treatment. METHODS: During a 7-year period, 282 patients with uBAVMs were surgically treated at our institution. Patient clinical features, post-surgical complications, AVM obliteration rate, seizure control and functional outcome were collected and analyzed. Seizure control was evaluated with the Engel Seizure Outcome Scale...
December 29, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/28030895/imaging-of-intracranial-hemorrhage
#9
Jeremy J Heit, Michael Iv, Max Wintermark
Intracranial hemorrhage is common and is caused by diverse pathology, including trauma, hypertension, cerebral amyloid angiopathy, hemorrhagic conversion of ischemic infarction, cerebral aneurysms, cerebral arteriovenous malformations, dural arteriovenous fistula, vasculitis, and venous sinus thrombosis, among other causes. Neuroimaging is essential for the treating physician to identify the cause of hemorrhage and to understand the location and severity of hemorrhage, the risk of impending cerebral injury, and to guide often emergent patient treatment...
December 12, 2016: Journal of Stroke
https://www.readbyqxmd.com/read/28017742/embolization-followed-by-radiosurgery-for-the-treatment-of-brain-arteriovenous-malformations-avms
#10
Michael P Marks, Mary L Marcellus, Justin Santarelli, Robert L Dodd, Huy M Do, Steven D Chang, John R Adler, Michael Mlynash, Gary K Steinberg
BACKGROUND: Embolization has been proposed to reduce the size of the AVM nidus in advance of radiosurgical treatment. However, embolization followed by radiosurgery for brain AVMs is controversial. OBJECTIVE: This study assessed the impact of embolization on nidal size prior to radiosurgical treatment and evaluated cure rates and complications using embolization followed by radiosurgery. METHODS: Retrospective review of our institutional AVM database identified 91 patients treated from 1995-2009 with embolization followed by radiosurgery...
December 22, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/28011359/detection-of-a-rare-complication-of-endovascular-treatment-for-brain-avm-by-echocardiography
#11
Mozhgan Parsaee, Sedigheh Saedi, Sepideh Emami, Alireza Serati
A brain arteriovenous malformation (AVM) is a congenital malformation of the vascular system, in which an abnormal short circuit (vascular malformation) connects cerebral arteries and veins. When the brain AVMs are diagnosed, the majority of them must be closed with surgical or endovascular treatment; because only a small portion of the brain AVMs remain asymptomatic during the patient's life. Endovascular trans-arterial embolization using Onyx is a suitable method of treating brain AVMs. Previously known complications of onyx usage are bleeding and neurologic deficits...
December 21, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/28009228/microsurgery-for-spetzler-ponce-class-a-and-b-arteriovenous-malformations-utilizing-an-outcome-score-adopted-from-gamma-knife-radiosurgery-a-prospective-cohort-study
#12
Michael K Morgan, Markus K Hermann Wiedmann, Marcus A Stoodley, Gillian Z Heller
OBJECTIVE The purpose of this study was to adapt and apply the extended definition of favorable outcome established for Gamma Knife radiosurgery (GKRS) to surgery for brain arteriovenous malformations (bAVMs). The aim was to derive both an error around the point estimate and a model incorporating angioarchitectural features in order to facilitate comparison among different treatments. METHODS A prospective microsurgical cohort was analyzed. This cohort included patients undergoing embolization who did not proceed to microsurgery and patients denied surgery because of perceived risk of treatment...
December 23, 2016: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28001255/giant-scalp-arteriovenous-malformation
#13
Paulo Valdeci Worm, Leonardo Gilmone Ruschel, Marcelo Rosa Roxo, Rafael Camelo
Arteriovenous malformations (AVMs) of the scalp are rare lesions. The clinical picture presents with complaints of increased scalp, scalp disfigurement, pain and neurological symptoms. Its origin can be congenital or traumatic. We present a case of giant scalp AVMs and its management, followed by a brief literature review on the subject. The diagnosis of scalp AVMs is based on physical examination and confirmed by internal and external carotid angiography or computed tomographic angiography (CTA). Surgical excision is especially effective in scalp AVMs, and is the most frequently used treatment modality...
December 2016: Revista da Associação Médica Brasileira
https://www.readbyqxmd.com/read/27999914/a-retrograde-transvenous-embolization-technique-with-balloon-assisted-arterial-aspiration-for-a-peripheral-arteriovenous-malformation-with-a-venous-pouch
#14
Asako Kuhara, Norimitsu Tanaka, Masamichi Koganemaru, Tomoko Kugiyama, Kensuke Kiyokawa, Toshi Abe
Management of arteriovenous malformations (AVMs) is challenging, and there is no consensus regarding either the ideal approach or the treatment timing. Percutaneous embolization is the most frequent approach currently used and is considered the first-line technique for AVMs. There is an ongoing discussion about the best technical approach to embolize AVMs. AVMs associated with a dominant outflow vein (DOV) are rare. Embolization of both the DOV and the nidus is considered more effective. Herein, we report a novel technique of transvenous embolization of a DOV under negative pressure from an arterial balloon catheter in a case of a peripheral AVM...
December 20, 2016: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/27999714/hypervascular-glioblastoma-multiforme-or-arteriovenous-malformation-associated-glioma-a-diagnostic-and-therapeutic-challenge-a-case-report
#15
Laura-Nanna Lohkamp, Christian Strong, Rafael Rojas, Matthew Anderson, Yosef Laviv, Ekkehard M Kasper
BACKGROUND: Simultaneous presentation of arteriovenous malformation (AVM) and glioblastoma multiforme (GBM) is rarely reported in the literature and needs to be differentiated from "angioglioma", a highly vascular glioma and other differential diagnosis such as hypervascular glioblastoma. Incorporating critical features of both, malignant glioma and AVM, such lesions lack a standard algorithm for diagnosis and therapy due to their rare incidence as well as their complex radiological and highly individualized clinical presentation...
2016: Surgical Neurology International
https://www.readbyqxmd.com/read/27991438/limitations-of-analytical-dose-calculations-for-small-field-proton-radiosurgery
#16
Changran Geng, Juliane Daartz, Kimberley Lam-Tin-Cheung, Marc Bussiere, Helen A Shih, Harald Paganetti, Jan Schuemann
The purpose of the work was to evaluate the dosimetric uncertainties of an analytical dose calculation engine and the impact on treatment plans using small fields in intracranial proton stereotactic radiosurgery (PSRS) for a gantry based double scattering system. 50 patients were evaluated including 10 patients for each of 5 diagnostic indications of: arteriovenous malformation (AVM), acoustic neuroma (AN), meningioma (MGM), metastasis (METS), and pituitary adenoma (PIT). Treatment plans followed standard prescription and optimization procedures for PSRS...
January 7, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/27982772/deliberate-employment-of-postoperative-hypotension-for-brain-arteriovenous-malformation-surgery-and-the-incidence-of-delayed-postoperative-hemorrhage-a-prospective-cohort-study
#17
Michael Kerin Morgan, Markus Karl Hermann Wiedmann, Nazih N A Assaad, Michael J A Parr, Gillian Z Heller
OBJECTIVE The aim of this study was to examine the impact of deliberate employment of postoperative hypotension on delayed postoperative hemorrhage (DPH) for all Spetzler-Ponce Class (SPC) C brain arteriovenous malformations (bAVMs) and SPC B bAVMs ≥ 3.5 cm in diameter (SPC B 3.5+). METHODS A protocol of deliberate employment of postoperative hypotension was introduced in June 1997 for all SPC C and SPC B 3.5+ bAVMs. The aim was to achieve a maximum mean arterial blood pressure (BP) ≤ 70 mm Hg (with cerebral perfusion pressure > 50 mm Hg) for a minimum of 7 days after resection of bAVMs (BP protocol)...
December 16, 2016: Journal of Neurosurgery
https://www.readbyqxmd.com/read/27973135/the-effectiveness-analysis-of-selected-radiosurgery-devices-on-treatment-of-cancer-tumors-and-arteriovenous-malformations-a-systematic-review
#18
M Davari, M Afzali, M Sabbagh-Bani-Azad, Z Sharif, F Hadizadeh, P Mirmoghtadaee, A Bakrani, S M Hoseini, F Kolahdoozan
No abstract text is available yet for this article.
November 2016: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/27916035/-microsurgical-management-and-outcomes-of-intramedullary-spinal-arteriovenous-malformations-a-report-of-14-cases
#19
L Zhang, W Q Jia, J Yang
Objective: To investigate the clinical features, microsurgical management and outcomes of intramedullary spinal arteriovenous malformations (AVM). Methods: A series of 14 patients (10 male, 4 female; mean age (39.1±17.2) years ranged from 16 to 72 years) with intramedullary spinal AVM who underwent microsurgical treatment from November 2008 to April 2015 in Department of Neurosurgery at Beijing Tiantan Hospital were retrospectively reviewed. The location of the AVM included cervical (n=6), thoracic (n=3), cervicothoracic (n=2), and conus medullaris (n=3)...
December 1, 2016: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://www.readbyqxmd.com/read/27913800/the-transvenous-pressure-cooker-technique-a-treatment-for-brain-arteriovenous-malformations
#20
Guang Zhang, Shiyi Zhu, Pei Wu, Shancai Xu, Huaizhang Shi
The treatment of brain arteriovenous malformations (AVMs) remains a significant challenge, especially hemorrhagic AVMs which are unsuitable for microsurgery or radiosurgery. We demonstrate an AVM located in the left basal ganglia area, supplied by slender arteries, and treated by the transvenous pressure cooker technique. Herein, we describe the procedure and outline the crucial points and indications for this technique.
December 2, 2016: Interventional Neuroradiology
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