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https://www.readbyqxmd.com/read/28821017/the-location-of-australian-buruli-ulcer-lesions-implications-for-unravelling-disease-transmission
#1
Arvind Yerramilli, Ee Laine Tay, Andrew J Stewardson, Peter G Kelley, Emma Bishop, Grant A Jenkin, Mike Starr, Janine Trevillyan, Andrew Hughes, N Deborah Friedman, Daniel P O'Brien, Paul D R Johnson
BACKGROUND: Buruli ulcer (BU), caused by Mycobacterium ulcerans, is increasing in incidence in Victoria, Australia. To improve understanding of disease transmission, we aimed to map the location of BU lesions on the human body. METHODS: Using notification data and clinical records review, we conducted a retrospective observational study of patients diagnosed with BU in Victoria from 1998-2015. We created electronic density maps of lesion locations using spatial analysis software and compared lesion distribution by age, gender, presence of multiple lesions and month of infection...
August 18, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28820949/association-between-patient-factors-and-outcome-of-synthetic-cartilage-implant-hemiarthroplasty-vs-first-metatarsophalangeal-joint-arthrodesis-in-advanced-hallux-rigidus
#2
Andy Goldberg, Dishan Singh, Mark Glazebrook, Chris M Blundell, Gwyneth De Vries, Ian L D Le, Dominic Nielsen, M Elizabeth Pedersen, Anthony Sakellariou, Matthew Solan, Alastair S E Younger, Timothy R Daniels, Judith F Baumhauer
BACKGROUND: We evaluated data from a clinical trial of first metatarsophalangeal joint (MTPJ1) implant hemiarthroplasty and arthrodesis to determine the association between patient factors and clinical outcomes. METHODS: Patients ≥18 years with hallux rigidus grade 2, 3, or 4 were treated with synthetic cartilage implant MTPJ1 hemiarthroplasty or arthrodesis. Pain visual analog scale (VAS), Foot and Ankle Ability Measure (FAAM) sports and activities of daily living (ADL) scores, and Short Form-36 Physical Function (SF-36 PF) subscore were obtained preoperatively, and at 2, 6, 12, 24, 52, and 104 weeks postoperatively...
August 1, 2017: Foot & Ankle International
https://www.readbyqxmd.com/read/28820722/house-structure-is-associated-with-plasmodium-falciparum-infection-in-a-low-transmission-setting-in-southern-zambia
#3
Matthew M Ippolito, Kelly M Searle, Harry Hamapumbu, Timothy M Shields, Jennifer C Stevenson, Philip E Thuma, William J Moss, For The Southern Africa International Center Of Excellence For Malaria Research
House structure may influence the risk of malaria by affecting mosquito entry and indoor resting. Identification of construction features associated with protective benefits could inform vector control approaches, even in low-transmission settings. We examined the association between house structure and malaria prevalence in a cross-sectional analysis of 2,788 children and adults residing in 866 houses in a low-transmission area of Southern Province, Zambia, over the period 2008-2012. Houses were categorized according to wall (brick/cement block or mud/grass) and roof (metal or grass) material...
August 7, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28820667/helping-young-people-stay-afloat-a-qualitative-study-of-community-resources-and-supports-for-lgbtq-adolescents-in-the-us-and-canada
#4
Marla E Eisenberg, Christopher J Mehus, Elizabeth M Saewyc, Heather L Corliss, Amy L Gower, Richard Sullivan, Carolyn M Porta
LGBTQ youth are at increased risk of poor health outcomes. This qualitative study gathered data from LGBTQ adolescents regarding their communities and describes the resources they draw upon for support. We conducted 66 go-along interviews with diverse LGBTQ adolescents (mean age = 16.6) in Minnesota, Massachusetts and British Columbia in 2014-2015, in which interviewers accompanied participants in their communities to better understand those contexts. Their responses were systematically organized and coded for common themes, reflecting levels of the social ecological model...
August 18, 2017: Journal of Homosexuality
https://www.readbyqxmd.com/read/28820636/clinical-effects-of-cpg-based-treatment-on-the-efficacy-of-hepatocellular-carcinoma-by-skewing-polarization-toward-m1-macrophage-from-m2
#5
Qing Zhang, Ru-Fei Yuan, Xiao-Huan Li, Tai-An Xu, Yan-Ni Zhang, Xiao-Lin Yuan, Yi-Fen Cui, Wan Shen, Qing-Lin Guan, Xiu-Yan Sun
OBJECTIVE: This study aims to explore the clinical efficacy of CpG-based therapy for treating hepatocellular carcinoma (HCC) by skewing polarization toward M1 macrophage from M2. METHODS: Pulmonary metastasis rate, overall survival time, and remission rate of 10 patients with HCC treated with transcatheter arterial chemoembolization (TACE) combined with CpG therapy and 10 age-, gender-, and TNM0-matched patients treated with TACE (control group) were compared. RESULTS: No pulmonary metastasis rate was 70% in the combined treatment group and 40% in the control group, respectively; and the differences between the two groups were statistically significant (p < 0...
August 2017: Cancer Biotherapy & Radiopharmaceuticals
https://www.readbyqxmd.com/read/28820613/influence-of-paddock-size-on-social-relationships-in-domestic-horses
#6
Katarzyna Majecka, Aneta Klawe
The aim of this study was to explore whether the size of paddocks affected social interactions within a group of horses. Furthermore, the effects of the gender composition in groups on social behavior were investigated. The research was done in a horse-riding center. A total of 78 horses and ponies, forming 3 groups, were included in the study. The time of the observation was divided into 2 periods. The data obtained from the 1st period (the horses were on relatively small paddocks) and the 2nd period (the paddocks were significantly bigger) were compared...
August 18, 2017: Journal of Applied Animal Welfare Science: JAAWS
https://www.readbyqxmd.com/read/28820545/assessment-and-management-of-acute-severe-mitral-regurgitation-in-the-intensive-care-unit
#7
Marina Leitman, Vladimir Tyomkin, Ehud Raanani, Ram Sharony, Ludmila Tzatskin, Eli Peleg, Alex Blatt, Zvi Vered
BACKGROUND: Acute severe mitral regurgitation (MR) is a serious medical condition. Whilst clear guidelines exist regarding the management of chronic MR, acute severe MR is usually treated on an individual basis. Currently, few data exist regarding acute MR in the era of primary coronary interventions (PCI). The present study included patients admitted to the Department of Cardiology during recent years with acute severe MR of different etiologies, and an analysis of these data in the light of previous investigations...
March 2017: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/28820539/a-survey-of-non-communicable-diseases-and-their-risk-factors-among-university-employees-a-single-institutional-study
#8
Emmanuel I Agaba, Maxwell O Akanbi, Patricia A Agaba, Amaka N Ocheke, Zumnan M Gimba, Steve Daniyam, Edith N Okeke
BACKGROUND: The incidence of non-communicable diseases (NCDs) is rising globally, with its attendant morbidity and mortality, especially in developing countries. This study evaluated the prevalence of NCDs and their risk factors among members of a university community. METHODS: All employees of the university were invited to the University health clinic for screening, using the World Health Organisation's STEPwise approach to NCDs. RESULTS: A total of 883 (521; 59...
August 15, 2017: Cardiovascular Journal of Africa
https://www.readbyqxmd.com/read/28820524/patterns-of-hand-grip-strength-and-detection-of-strength-loss-in-patients-undergoing-bone-marrow-transplantation-a-feasibility-study
#9
Cindy A Sayre, Basia Belza, Kathleen Shannon Dorcy, Elizabeth Phelan, JoAnne D Whitney
PURPOSE/OBJECTIVES: To determine the feasibility of measuring hand grip strength (HGS) daily in a population of recipients of bone marrow transplantation (BMT), to describe changes in strength measured by HGS, and to describe relationships between laboratory values (hematocrit, hemoglobin, and absolute neutrophil count) and HGS.
. DESIGN: Prospective, longitudinal, repeated measures, within subject.
. SETTING: Inpatient units at the University of Washington Medical Center in Seattle...
September 1, 2017: Oncology Nursing Forum
https://www.readbyqxmd.com/read/28820448/vitamin-d-status-of-residents-in-taiyuan-china-and-influencing-factors
#10
Xiaoning Yan, Jasmine S Thomson, Ruibao Zhao, Ruifang Zhu, Zhaolin Wang, Na Zhang, Jane Coad
High prevalence of vitamin D deficiency has been reported worldwide. Residents of Taiyuan, China, were predicted to be at high risk of vitamin D deficiency due to its high latitude, heavy air pollution, and cultural sun avoidance. This study investigated the vitamin D status of office workers, and explored the potential determinants of capillary 25-hydroxyvitamin D (25(OH)D) concentration as well as the relationship between 25(OH)D and metabolic syndrome. Two hundred participants, aged 20 to 80 years, were recruited...
August 18, 2017: Nutrients
https://www.readbyqxmd.com/read/28820435/healthy-ageing-in-people-with-intellectual-disabilities-from-managers-perspective-a-qualitative-study
#11
Maria Johansson, Petra Björne, Ingrid Runesson, Gerd Ahlström
An increasing number of people with intellectual disability (ID) are reaching older ages today although they experience more health problems than the older population without ID. Leaders in intellectual disability services can greatly influence the conditions for a healthy ageing, and the aim of the present study was to explore healthy ageing in this group from the perspective of the leaders. Interviews with 20 leaders were subjected to qualitative content analysis. The findings gave rise to the overall theme ageing in dependence, which emerged from the following six categories: Supporting self-determination; Inaccessible activities after retirement; Signs of decline; Increased and specific needs for support and care; A non-question of gender; Aspects concerning the end of life and death...
August 18, 2017: Healthcare (Basel, Switzerland)
https://www.readbyqxmd.com/read/28820347/association-between-eye-diagnosis-and-positive-syphilis-test-results-in-a-large-urban-sexually-transmitted-infection-primary-care-clinic-population
#12
Ann-Marie Lobo, Yan Gao, Laura Rusie, Magda Houlberg, Supriya D Mehta
In 2015, the Centers for Disease Control and Prevention (CDC) and the American Academy of Ophthalmology (AAO) released clinical advisories on rising cases of ocular syphilis. We examined the association between eye disease and syphilis infection among primary care and sexually transmitted infection (STI) clinic patients attending an urban lesbian, gay, bisexual, transgender (LGBT) health center. We conducted a retrospective medical record review of all patients who underwent syphilis testing at Howard Brown Health between 1 January 2010 and 31 December 2015...
January 1, 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/28820157/incidence-outcomes-and-risk-factors-for-hemorrhagic-complications-in-eyes-with-polypoidal-choroidal-vasculopathy-following-photodynamic-therapy-in-indian-subjects
#13
Pukhraj Rishi, Ekta Rishi, Minal Sharma, Aditya Maitray, Muna Bhende, Lingam Gopal, Tarun Sharma, Dhanashree Ratra, Parveen Sen, Pramod Bhende, Chetan Rao, Pradeep Susvar
PURPOSE: To evaluate the incidence, outcomes, and risk factors for hemorrhagic complications in eyes with polypoidal choroidal vasculopathy (PCV) following photodynamic therapy (PDT). METHODS: Medical records of 94 eyes of 86 consecutive patients with PCV who underwent PDT between January 2007 and December 2014 were retrospectively reviewed. The diagnosis of PCV was based on clinical features and indocyanine green angiography. Eyes were treated with PDT monotherapy or a combination of PDT plus anti-vascular endothelial growth factor...
August 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28820152/back-pain-in-ophthalmology-national-survey-of-indian-ophthalmologists
#14
Ramesh Venkatesh, Sumit Kumar
PURPOSE: The aim is to assess the prevalence, severity, and associations of back pain among Indian ophthalmologists. METHODS: A self-reporting questionnaire was sent to ophthalmologists with valid e-mail addresses registered with the All India Ophthalmological Society. The survey was open for responses for 2 months. RESULTS: A total of 651 (5.96%) responses were obtained; 394 (61%) males and 257 (39%) females. Half (50%) of responses were obtained from doctors belonging to 31-40 years' age group...
August 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28820019/the-supplemental-nutrition-assistance-program-and-frequency-of-sugar-sweetened-soft-drink-consumption-among-low-income-adults-in-the-us
#15
Jiyeun Park, Hsien-Chang Lin, Chao-Ying Peng
BACKGROUND: The Supplemental Nutrition Assistance Program (SNAP) was designed to help low-income people purchase nutritious foods in the US. In recent years, there has been a consistent call for banning purchases of sugar drinks in SNAP. AIM: The aim of this study was to examine the association between SNAP participation and the frequency of sugar-sweetened soft drink (SSD) consumption among low-income adults in the US. METHOD: Data came from the 2009-2010 National Health and Nutrition Examination Survey...
January 1, 2017: Nutrition and Health
https://www.readbyqxmd.com/read/28819919/the-microbial-mother-meets-the-independent-organ-cultural-discourses-of-reproductive-microbiomes
#16
Jessica R Houf
The human microbiome is changing the way experts and non-experts think about germs and microorganisms. This essay is a gender analysis of contemporary discourses surrounding the human reproductive microbiome, specifically the vaginal microbiota and the penile microbiota. I first historically situate the human reproductive microbiome within the germ theory of disease. Then, I draw on Heather Paxson's Foucauldian and Latourian concept of microbiopolitics to argue that microbiopolitics is not only about how humans should live with microorganisms; but it also impacts how humans and microbes live together as gendered beings...
August 17, 2017: Journal of Medical Humanities
https://www.readbyqxmd.com/read/28819913/chemoradiation-and-local-excision-for-t2n0-rectal-cancer-offers-equivalent-overall-survival-compared-to-standard-resection-a-national-cancer-database-analysis
#17
Lawrence Lee, Justin Kelly, George J Nassif, Sam B Atallah, Matthew R Albert, Ravi Shridhar, John R T Monson
BACKGROUND: Local excision (LE) alone is associated with worse survival compared to radical surgery (RS) for T2 rectal cancer, but LE with additional chemoradiation (CRT) may improve outcomes. The objective of this study was to compare combined CRT and LE versus RS for T2 rectal cancer. METHODS: The 2004-2014 National Cancer Database was queried for patients with T2N0M0 rectal cancer undergoing LE with neoadjuvant(NA-CRT + LE) or adjuvant(LE + Adj-CRT) CRT, or RS...
August 17, 2017: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/28819911/neighborhood-family-and-peer-factors-associated-with-early-adolescent-smoking-and-alcohol-use
#18
Christopher Cambron, Rick Kosterman, Richard F Catalano, Katarina Guttmannova, J David Hawkins
There is broad agreement that neighborhood contexts are important for adolescent development, but there is less consensus about their association with adolescent smoking and alcohol use. Few studies have examined associations between neighborhood socioeconomic contexts and smoking and alcohol use while also accounting for differences in family and peer risk factors for substance use. Data drawn from the Seattle Social Development Project (N = 808), a gender-balanced (female = 49%), multiethnic, theory-driven longitudinal study originating in Seattle, WA, were used to estimate trajectories of smoking and alcohol use from 5th to 9th grade...
August 18, 2017: Journal of Youth and Adolescence
https://www.readbyqxmd.com/read/28819897/teachers-and-parents-perspectives-on-a-curricular-subject-of-religion-and-spirituality-for-indian-schools-a-pilot-study-toward-school-mental-health-program
#19
Parameshwaran Ramakrishnan, Andrew Baccari, Uma Ramachandran, Syed Faiz Ahmed, Harold G Koenig
Religious-spiritual (R/S) education helps medical students cope with caregiving stress and gain skills in interpersonal empathy needed for clinical care. Such R/S education has been introduced into K-12 and college curricula in some developed nations and has been found to positively impact student's mental health. Such a move has not yet been seen in the Indian education system. This paper aimed to examine perspectives of teachers and parents in India on appropriateness, benefits, and challenges of including R/S education into the school curriculum and also to gather their impressions on how a R/S curriculum might promote students' health...
August 17, 2017: Journal of Religion and Health
https://www.readbyqxmd.com/read/28819755/importance-of-fna-technique-for-decreasing-non-diagnostic-rates-in-thyroid-nodules
#20
Amarbir S Gill, Richard Amdur, Arjun S Joshi
To identify potential interventions that may lower the high non-diagnostic rates associated with ultrasound guided (US) fine needle aspiration (FNA) biopsy of the thyroid nodule. A case series of 164 thyroid nodule US-guided FNA was identified retrospectively. The following variables were analyzed in regards to diagnostic and non-diagnostic sampling: patient age, gender, size of nodule, biopsy technique (capillary vs. aspiration), needle gauge (23 vs. 25), and physician experience. The FNA diagnosis, and final pathology, when applicable, was recorded for each sample using the Bethesda criteria...
August 17, 2017: Head and Neck Pathology
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