keyword
MENU ▼
Read by QxMD icon Read
search

Adrenalectomy

keyword
https://www.readbyqxmd.com/read/29655957/ectopic-cushing-syndrome-report-of-9-cases
#1
Marta Araujo Castro, Nuria Palacios García, Javier Aller Pardo, Cristina Izquierdo Alvarez, Laura Armengod Grao, Javier Estrada García
INTRODUCTION: Ectopic Cushing's syndrome (ECS) is a rare condition caused by ACTH secretion by extrapituitary tumors. Its low frequency makes it difficult to acquire experience in its management. The aim of this study was to describe patients with ECS seen at the endocrinology department of a tertiary hospital over 15 years. METHODS: This was a retrospective study of the clinical, biochemical and radiographic data, treatment, and course of patients with ECS seen from 2000 to 2015...
April 11, 2018: Endocrinología, Diabetes y Nutrición
https://www.readbyqxmd.com/read/29651813/contralateral-adrenal-width-predicts-the-duration-of-prolonged-post-surgical-steroid-replacement-for-subclinical-cushing-syndrome
#2
Masahiro Sugiura, Yusuke Imamura, Koji Kawamura, Satoshi Yamamoto, Tomokazu Sazuka, Kazuyoshi Nakamura, Shinichi Sakamoto, Hidekazu Nagano, Hisashi Koide, Tomoaki Tanaka, Takashi Imamoto, Akira Komiya, Tomohiko Ichikawa
OBJECTIVES: To identify pre-treatment factors affecting the duration of post-surgical steroid replacement in patients undergoing adrenalectomy for subclinical Cushing syndrome. METHODS: The present retrospective analysis included 64 patients who underwent unilateral laparoscopic adrenalectomy for subclinical Cushing syndrome. Adrenal tumor and contralateral adrenal sizes together with various clinical factors were studied in association with the duration of post-surgical steroid replacement...
April 12, 2018: International Journal of Urology: Official Journal of the Japanese Urological Association
https://www.readbyqxmd.com/read/29642441/transcriptome-profile-in-unilateral-adrenalectomy-induced-compensatory-adrenal-growth-in-the-rat
#3
Karol Jopek, Marianna Tyczewska, Piotr Celichowski, Ludwik K Malendowicz, Marcin Rucinski
Compensatory adrenal growth evoked by unilateral adrenalectomy (hemiadrenalectomy) constitutes one of the most frequently studied in vivo models of adrenocortical enlargement. This type of growth has been quite well characterized for its morphological, biochemical, and morphometric parameters. However, the molecular basis of compensatory adrenal growth is poorly understood. Therefore, the aim of this study was to investigate the rat adrenal transcriptome profile during the time of two previously described adrenocortical proliferation waves at 24 and 72 h after unilateral adrenalectomy...
April 7, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29629868/computed-tomography-identified-factors-that-preclude-living-kidney-donation
#4
Katerina Mastrocostas, Christina M Chingkoe, Kenneth T Pace, Joseph J Barfett, Anish Kirpalani, Gevork N Mnatzakanian, Paraskevi A Vlachou, Errol Colak
INTRODUCTION: The purpose of this study was to determine the variety and prevalence of renal and non-renal abnormalities detected on multi-detector computed tomography (MDCT) that precluded patients from donating a kidney. METHODS: Institutional review board approval was obtained and the requirement for informed consent was waived. A retrospective, single-centre review of 701 patients (444 female, 257 male; age range 18-86 years; mean age 43.2±11.9 years) that underwent renal donor protocol MDCT was conducted...
April 6, 2018: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/29624291/neonatal-genistein-exposure-and-glucocorticoid-signaling-in-the-adult-mouse-uterus
#5
Shannon D Whirledge, Edwina P Kisanga, Robert H Oakley, John A Cidlowski
BACKGROUND: Female reproductive tract development is sensitive to the endocrine-disrupting potential of environmental estrogens. Early-life exposure to the dietary phytoestrogen genistein impairs fertility and persistently alters the transcriptome in the oviduct and uterus of rodents. Glucocorticoid signaling, which has recently been shown to be essential for normal fertility in the female mouse uterus, is antagonized by genistein. OBJECTIVE: Our goal was to determine whether early-life exposure to genistein disrupts glucocorticoid signaling in the mouse uterus, which may contribute to infertility...
April 5, 2018: Environmental Health Perspectives
https://www.readbyqxmd.com/read/29622713/uncommon-presentation-rare-complication-and-previously-undescribed-oncologic-association-of-pheochromocytoma-the-great-masquerader
#6
David Lawrence, Kevan Salimian, Thorsten Leucker, Seth Martin
We describe the case of a 67-year-old man presenting with ventricular tachycardia (VT) and systolic heart failure secondary to a left adrenal phaeochromocytoma. After treatment with amiodarone, the patient's VT resolved. However, his course was complicated by femoral deep venous thrombosis secondary to an incidentally discovered dedifferentiated liposarcoma of the thigh, for which he was prescribed a course of enoxaparin. The patient was discharged with plans for adrenalectomy following achievement of sufficient preoperative heart rate and blood pressure control with alpha-adrenergic receptor blockade, but re-presented to an outside facility in haemorrhagic shock, where he ultimately expired...
April 5, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29621813/cushing-s-syndrome-a-historic-review-of-the-treatment-strategies-and-corresponding-outcomes-in-a-single-tertiary-center-over-the-past-half-century
#7
Anelia Nankova, Maria Yaneva, Atanaska Elenkova, Dimitar Tcharaktchiev, Marin Marinov, Asen Hadzhiyanev, Tanyo Sechanov, Georgi Gantchev, Georgi Todorov, Georgi Kirilov, Krasimir Kalinov, Maria Andreeva, Sabina Zacharieva
Cushing's syndrome (CS) is associated with serious comorbidities and an increased mortality rate that could be reduced only if strict biochemical control is achieved. The aim of this study was to show the 50-year experience of a single tertiary center in the management of CS patients - the different treatment modalities used over the years and the corresponding outcomes. It was a retrospective study of a large cohort of patients from the Bulgarian CS database: 613 patients (374 with ACTH-dependent and 239 with ACTH-independent CS)...
April 2018: Hormone and Metabolic Research, Hormon- und Stoffwechselforschung, Hormones et Métabolisme
https://www.readbyqxmd.com/read/29609826/results-of-adrenalectomy-in-lung-cancer-metastases
#8
A Jalón-Monzón, D Castanedo-Álvarez, M A Hevia-Suárez, M Álvarez-Múgica, A Medina-González, S Escaf-Barmadah
BACKGROUND: The aim of this study was to report our centre's experience over the past 15 years with patients with lung carcinoma and adrenal metastases treated sequentially with lung resection and adrenalectomy. PATIENTS AND METHODS: We analysed a retrospective series of 19 patients who underwent adrenalectomy for lung carcinoma metastasis. All patients were operated on at the same centre, between October 2000 and October 2015. We performed a descriptive analysis and an overall survival and disease-free survival analysis...
March 30, 2018: Actas Urologicas Españolas
https://www.readbyqxmd.com/read/29606881/open-adrenalectomy-versus-laparoscopic-adrenalectomy-for-adrenocortical-carcinoma-a-retrospective-comparative-study-on-short-term-oncologic-prognosis
#9
Guo-Yang Zheng, Han-Zhong Li, Jian-Hua Deng, Xue-Bin Zhang, Xing-Cheng Wu
Purpose: Open adrenalectomy (OA) remains the gold standard of surgical therapy for adrenocortical carcinoma, while the role of laparoscopic approach is controversial. We aim to explore the influence of surgical approaches on the oncologic prognosis of adrenocortical carcinoma by comparing the short-term outcomes of patients undergoing OA with those undergoing laparoscopic adrenalectomy (LA). Patients and methods: We retrospectively analyzed the baseline characteristics, perioperative data and short-term prognosis of 42 patients diagnosed with stage I-III adrenocortical carcinoma, receiving OA (n=22) and LA (n=20) as primary therapy...
2018: OncoTargets and Therapy
https://www.readbyqxmd.com/read/29604138/glucocorticoid-withdrawal-affects-stress-induced-changes-of-urocortin-2-gene-expression-in-rat-adrenal-medulla-and-brain
#10
Andrej Tillinger, Ľubica Horváthová, Regina Nostramo, Lidia I Serova, Richard Kvetňanský, Esther L Sabban, Boris Mravec
Corticotropin-releasing factor is well known activator of the hypothalamic-pituitary-adrenocortical axis, that represents crucial system participating on stress response of the organism. Urocortins are members of the corticotropin-releasing factor family of peptides with proposed effects on neuroendocrine and behavioral stress response mechanisms. Urocortin 2, one of three known urocortins, is present in central and peripheral stress response system and its expression can be augmented by glucocorticoids. In the present study we have examined how glucocorticoid withdrawal affects urocortin 2 gene expression after acute immobilization in the adrenal medulla and selected brain areas in rats...
March 31, 2018: Journal of Neuroendocrinology
https://www.readbyqxmd.com/read/29592980/metastatic-pheochromocytoma-in-men-2a-a-rare-association
#11
Rimesh Pal, Ashu Rastogi, Santosh Kumar, Anil Bhansali
A 45-year-old woman was diagnosed as having multiple endocrine neoplasia type 2A in 2014. She had bilateral pheochromocytoma, medullary thyroid carcinoma and biopsy-proven cutaneous lichen amyloidosis in the interscapular area. She underwent bilateral adrenalectomy; following which, she achieved clinical and biochemical remission. She was planned for total thyroidectomy at a later date; however, she was lost to follow-up. She presented to us again in December 2016 with abdominal pain. Examination revealed hypertension with postural drop...
March 28, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29587644/a-novel-germline-armc5-mutation-in-a-patient-with-bilateral-macronodular-adrenal-hyperplasia-a-case-report
#12
Qiuli Liu, Dali Tong, Jing Xu, Xingxia Yang, Yuting Yi, Dianzheng Zhang, Luofu Wang, Jun Zhang, Yao Zhang, Yaoming Li, Lianpeng Chang, Rongrong Chen, Yanfang Guan, Xin Yi, Jun Jiang
BACKGROUND: Bilateral macronodular adrenal hyperplasia (BMAH) is a rare cause of Cushing's syndrome (CS). BMAH is predominantly believed to be caused by two mutations, a germline and somatic one, respectively, as described in the two-hit hypothesis. In many familial cases of BMAH, mutations in armadillo repeat containing 5 (ARMC5), a putative tumor suppressor gene, are thought to induce the disorder. The objective of this study was to report a case in which the patient presented with BMAH induced by a novel heterozygous germline ARMC5 mutation (c...
March 27, 2018: BMC Medical Genetics
https://www.readbyqxmd.com/read/29581611/obesity-does-not-affect-peri-and-postoperative-outcomes-of-transabdominal-laparoscopic-adrenalectomy
#13
Takahiro Inaishi, Toyone Kikumori, Dai Takeuchi, Hiromasa Ishihara, Noriyuki Miyajima, Masahiro Shibata, Yuko Takano, Kenichi Nakanishi, Sumiyo Noda, Yasuhiro Kodera
Laparoscopic adrenalectomy is the gold standard procedure for most adrenal tumors. Obesity is considered as a risk factor for surgical complications. This study aimed to evaluate whether obesity affects peri- and postoperative outcomes of transabdominal laparoscopic adrenalectomy using body mass index (BMI). This retrospective study included 98 patients who underwent transabdominal laparoscopic adrenalectomy between January 2011 and December 2016. We divided the patients into 2 groups: non-obese group (BMI < 25 kg/m2) and obese group (BMI ≥ 25 kg/m2)...
February 2018: Nagoya Journal of Medical Science
https://www.readbyqxmd.com/read/29579167/glucocorticoid-receptor-signaling-is-not-required-for-in-vivo-adipogenesis
#14
Kevin T Bauerle, Irina Hutson, Erica L Scheller, Charles A Harris
Regulation of adipogenesis is of significant interest given that adipose tissue expansion and dysfunction are central to metabolic syndrome. Glucocorticoids (GCs) are important for adipogenesis in vitro. However, a role for GCs in adipogenesis in vivo has been difficult to establish. Glucocorticoid receptor (GR)-null mice die at birth, a time at which wild-type mice do not have fully developed white adipose depots. We have conducted several studies aimed at defining the role of GC signaling in adipogenesis in vitro and in vivo...
March 19, 2018: Endocrinology
https://www.readbyqxmd.com/read/29578911/adrenal-metastasectomy-in-the-presence-and-absence-of-extraadrenal-metastatic-disease
#15
Ashley E Russo, Brian R Untch, Mark G Kris, Joanne F Chou, Marinela Capanu, Daniel G Coit, Jamie E Chaft, Michael I D'Angelica, Murray F Brennan, Vivian E Strong
OBJECTIVE: To determine if there are differences in overall survival (OS) or event-free survival (EFS) in patients with and without concomitant extra-adrenal metastases undergoing adrenal metastasectomy. BACKGROUND: There is growing interest in the use of local therapies in patients with oligometastatic disease. Previously published series have indicated that long-term survival is possible with resection. Adrenalectomy has been used to treat adrenal metastases in select patients...
March 23, 2018: Annals of Surgery
https://www.readbyqxmd.com/read/29572370/two-cases-of-hypokalaemic-rhabdomyolysis-same-but-different
#16
Philipp Pecnik, Petra Müller, Sybille Vrabel, Martin Windpessl
In this paper, we present two women with hypokalaemic rhabdomyolysis in the context of increased diuretic intake and gastroenteritis, respectively. While their clinical manifestations and laboratory results were strikingly similar, two different underlying disorders were subsequently unveiled. The first patient was diagnosed with Conn syndrome, and adrenalectomy led to significant improvement of hypertension and sustained normokalaemia. The diagnosis in the second patient was Gitelman syndrome. Electrolyte supplements improved long-term lassitude and the frequency of muscle cramps declined significantly...
March 22, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29563743/adrenal-schwannoma-treated-with-open-adrenalectomy-a-case-report
#17
Prakash Hebbulse Shivalingaiah, Pradeep Kumar, Suyash Bajoria
Adrenal schwannomas are very rare tumors accounting for only 0.2% of the adrenal tumors. These are very difficult to diagnose preoperatively and usually present as incidental non-secreting adrenal masses in asymptomatic patients or in patients with non-specific complaints. Computed tomography (CT) and magnetic resonance imaging (MRI) are required to aid the diagnosis, but adrenal schwannomas cannot be distinguishably confirmed on the basis of imaging alone. Histopathological examination (HPE) is essential for accurate diagnosis...
March 2018: Indian Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29560790/unilateral-adrenal-hematoma-with-associated-giant-mass-a-report-of-two-cases
#18
Yoshitaka Uji
BACKGROUND: Adrenal hematoma is a rare yet potentially life-threatening event that occurs both in traumatic conditions and in a variety of nontraumatic conditions. In the present study, we report the two cases with idiopathic unilateral adrenal hematoma. CASE PRESENTATION: Case 1 involved a 72-year-old man who was complaining of upper abdominal pain. Abdominal computed tomography (CT) and magnetic resonance imaging (MRI) demonstrated a giant mixed density tumor in the right retroperitoneal space...
March 21, 2018: Acta Chirurgica Belgica
https://www.readbyqxmd.com/read/29555192/arterial-stiffness-evaluated-by-pulse-wave-velocity-is-not-predictive-of-the-improvement-in-hypertension-after-adrenal-surgery-for-primary-aldosteronism-a-multicentre-study-from-the-french-european-society-of-hypertension-excellence-centres
#19
Béatrice Bouhanick, Jacques Amar, Laurence Amar, Philippe Gosse, Xavier Girerd, Yves Reznik, Claire Mounier-Vehier, Jean Philippe Baguet, Pierre Boutouyrie, Benoit Lepage, Pierre Lantelme, Bernard Chamontin
BACKGROUND: Predictive factors associated with normal blood pressure (BP) after unilateral adrenalectomy for primary aldosteronism (PA) are not clearly identified. AIMS: To evaluate the predictive value of arterial stiffness before surgery on BP after surgery. METHODS: During 2009-2013, 96 patients with PA due to unilateral adrenal adenoma who underwent surgery were enrolled in a multicentre open-label, prospective study. Aortic pulse wave velocity (PWV) was assessed before surgery...
March 16, 2018: Archives of Cardiovascular Diseases
https://www.readbyqxmd.com/read/29554355/bilateral-adrenalectomy-in-congenital-adrenal-hyperplasia-a-systematic-review-and-meta-analysis
#20
Diana MacKay, Anna Nordenström, Henrik Falhammar
Context: Management of congenital adrenal hyperplasia (CAH) involves suppression of the hypothalamic-pituitary-adrenal (HPA) axis using supraphysiological doses of exogenous glucocorticoids. This can pose a challenge, with Cushing's syndrome being a frequent complication of adequate suppression. Bilateral adrenalectomy, with subsequent replacement of glucocorticoids and mineralocorticoids at physiological doses, has been proposed as an alternative therapeutic strategy. Objective: To review the outcomes following bilateral adrenalectomy for CAH...
March 15, 2018: Journal of Clinical Endocrinology and Metabolism
keyword
keyword
4016
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"