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https://www.readbyqxmd.com/read/29684805/detecting-a-rare-composite-small-bowel-lymphoma-by-magnetic-resonance-imaging-coincidentally-a-case-report-with-radiological-surgical-and-histopathological-features
#1
M Pezzella, B Brogna, A Romano, F Torelli, G Esposito, M Petrillo, F M Romano, N Di Martino, A Reginelli, R Grassi
INTRODUCTION: Diagnosing lymphoma continues to prove challenging in the clinical practice. Composite lymphoma (CL) is defined by the coexistence of different lymphoma subtypes in the same anatomical location. This condition has seldom been witnessed in the gastrointestinal (GI) tract. We weren't able to find previous cases in the literature about small bowel CL with follicular lymphoma (FL) and classical Hodgkin lymphoma (CHL). Surgery is the treatment of choice to obtain accurate histology, to manage and prevent acute complications...
April 16, 2018: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29684498/multi-modal-characterization-of-vasculature-and-nanoparticle-accumulation-in-five-tumor-xenograft-models
#2
Einar Sulheim, Jana Kim, Annemieke van Wamel, Eugene Kim, Sofie Snipstad, Igor Vidic, Ingeborg Hovde Grimstad, Marius Widerøe, Sverre H Torp, Steinar Lundgren, David J Waxman, Catharina de Lange Davies
Preclinical research has demonstrated that nanoparticles and macromolecules can accumulate in solid tumors due to the enhanced permeability and retention effect. However, drug loaded nanoparticles often fail to show increased efficacy in clinical trials. A better understanding of how tumor heterogeneity affects nanoparticle accumulation could help elucidate this discrepancy and help in patient selection for nanomedicine therapy. Here we studied five human tumor models with varying morphology and evaluated the accumulation of 100 nm polystyrene nanoparticles...
April 20, 2018: Journal of Controlled Release: Official Journal of the Controlled Release Society
https://www.readbyqxmd.com/read/29684257/reliability-of-neurometabolite-detection-with-two-dimensional-localized-correlation-spectroscopy-at-3t
#3
Jameen Arm, Oun Al-Iedani, Scott Quadrelli, Karen Ribbons, Rod Lea, Jeannette Lechner-Scott, Saadallah Ramadan
BACKGROUND: Two-dimensional localized correlational spectroscopy (2D L-COSY) has been applied in vivo to investigate metabolic profiles in many disorders due to its ability to detect several metabolites simultaneously. Successful application of this technique depends on the reliability of the detection and understanding of the variability result from test-retest measurements. PURPOSE: To evaluate the test-retest repeatability/reliability of 2D L-COSY in detecting brain metabolites in a phantom and healthy subjects in a 3T scanner...
April 23, 2018: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/29684224/mismatch-negativity-and-cortical-thickness-in-patients-with-schizophrenia-and-bipolar-disorder
#4
Sungkean Kim, Hyeonjin Jeon, Kuk-In Jang, Yong-Wook Kim, Chang-Hwan Im, Seung-Hwan Lee
Introduction: Mismatch negativity (MMN) is a measure of automatic neurophysiological brain processes for detecting unexpected sensory stimuli. This study investigated MMN reduction in patients with schizophrenia and bipolar disorder and examined whether cortical thickness is associated with MMN, for exploratory purposes. Methods: Electroencephalograms were recorded in 38 patients with schizophrenia, 37 patients with bipolar disorder, and 32 healthy controls (HCs) performing a passive auditory oddball paradigm...
April 19, 2018: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/29684133/neural-activation-during-delay-discounting-is-associated-with-6-month-change-in-risky-sexual-behavior-in-adolescents
#5
Casey K Gardiner, Hollis C Karoly, Rachel E Thayer, Arielle S Gillman, Amithrupa Sabbineni, Angela D Bryan
Background: Identifying cognitive and neural mechanisms of decision making in adolescence can enhance understanding of, and interventions to reduce, risky health behaviors in adolescence. Delay discounting, or the propensity to discount the magnitude of temporally distal rewards, has been associated with diverse health risk behaviors, including risky sex. This cognitive process involves recruitment of reward and cognitive control brain regions, which develop on different trajectories in adolescence and are also implicated in real-world risky decision making...
April 19, 2018: Annals of Behavioral Medicine: a Publication of the Society of Behavioral Medicine
https://www.readbyqxmd.com/read/29684132/prefrontal-cortical-activity-during-the-stroop-task-new-insights-into-the-why-and-the-who-of-real-world-risky-sexual-behavior
#6
Emily Barkley-Levenson, Feng Xue, Vita Droutman, Lynn C Miller, Benjamin J Smith, David Jeong, Zhong-Lin Lu, Antoine Bechara, Stephen J Read
Background: Research suggests that deficits in both executive functioning and trait impulsivity may play a role in risky sexual behavior. At the neural level, differences in regulation of the prefrontal cortex have been linked to impulsivity, measured neurocognitively and through self-report. The relationship between neurocognitive measures of executive control and trait impulsivity in predicting risky sexual behavior has not been investigated. Purpose: To investigate the relationship between neural functioning during the Stroop task and risky sexual behavior, as well as the effect of individual differences in urgent (positive and negative) impulsivity on this relationship...
April 19, 2018: Annals of Behavioral Medicine: a Publication of the Society of Behavioral Medicine
https://www.readbyqxmd.com/read/29684119/aortic-stiffness-in-adolescent-turner-and-marfan-syndrome-patients
#7
Michal Schäfer, Lorna P Browne, Uyen Truong, James J Jaggers, Max B Mitchell, Ladonna Malone, Gareth Morgan, Kathryn Chatfield, Daniel McLennan, Harma Turbendian, Danial Vargas, Brian Fonseca, Michael DiMaria, Anar Shah, Margaret P Ivy, Alex J Barker, Kendall S Hunter, Neil Wilson, D Dunbar Ivy, David N Campbell
OBJECTIVES: Turner syndrome (TS) and Marfan syndrome (MFS) are partially characterized by aortopathies with a risk of developing severe aortic dilation, stiffness and consequent dissection and aneurysm formation. The incidence of a bicuspid aortic valve (BAV) is also increased in TS. We investigated aortic stiffness in teenage TS and MFS patients and evaluated to what degree stiffness in TS patients is augmented by the presence of a BAV. METHODS: Fifty-seven patients with TS (n = 37) and MFS (n = 20), as well as 22 controls with similar age and size distribution underwent evaluation of thoracic aortic stiffness using phase-contrast magnetic resonance imaging...
April 19, 2018: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29684004/the-neural-system-of-metacognition-accompanying-decision-making-in-the-prefrontal-cortex
#8
Lirong Qiu, Jie Su, Yinmei Ni, Yang Bai, Xuesong Zhang, Xiaoli Li, Xiaohong Wan
Decision-making is usually accompanied by metacognition, through which a decision maker monitors uncertainty regarding a decision and may then consequently revise the decision. These decisional metacognitive processes can occur prior to or in the absence of feedback. However, the neural mechanisms of metacognition remain controversial. One theory proposes an independent neural system for metacognition in the prefrontal cortex (PFC); the other, that metacognitive processes coincide and overlap with the systems used for the decision-making process per se...
April 23, 2018: PLoS Biology
https://www.readbyqxmd.com/read/29683970/endoscopic-ultrasound-based-pancreatic-cancer-screening-of-high-risk-individuals-a-prospective-observational-trial
#9
Alexandra Gangi, Mokenge Malafa, Jason Klapman
OBJECTIVES: Pancreatic cancer (PC), a common cause of cancer death, is rarely diagnosed at an early stage. Early detection of PC may improve outcomes in affected patients. This study evaluated the utility of screening of high-risk individuals (HRIs) using an endoscopic ultrasound (EUS)-only approach to detect early malignant changes. METHODS: A prospective PC screening program for HRIs was opened in 2007. Fifty-eight patients have enrolled to date. Patients with normal EUS examinations underwent repeat EUS annually for 5 years...
April 19, 2018: Pancreas
https://www.readbyqxmd.com/read/29683969/diagnostic-accuracy-of-preoperative-imaging-for-differentiation-of-branch-duct-versus-mixed-duct-intraductal-papillary-mucinous-neoplasms
#10
Emmanuel E Ugbarugba, Carmen Grieco, Phil A Hart, Feng Li, Brett Sklaw, Kevin Cronley, Veeral M Oza, Benjamin J Swanson, Jon P Walker, Samer El-Dika, Darwin L Conwell, Somashekar G Krishna
OBJECTIVE: The aim of this study is to determine the diagnostic accuracy of preoperative evaluation to detect main pancreatic duct involvement in pancreatic cystic lesions thus differentiating mixed intraductal papillary mucinous neoplasm (IPMN) from branch duct (BD)-IPMN. METHODS: The pathology database of pancreatic resections from 2000 to 2014 was reviewed. Main pancreatic duct-IPMNs and IPMNs with intracystic mass/nodules were excluded. The preoperative test characteristics were analyzed using surgical histopathology as the "gold standard...
April 19, 2018: Pancreas
https://www.readbyqxmd.com/read/29683947/encephalocraniocutaneous-lipomatosis
#11
Abhishek Bavle, Rikin Shah, Naina Gross, Theresa Gavula, Alejandro Ruiz-Elizalde, Klaas Wierenga, Rene McNall-Knapp
A 5-year-old boy presented with worsening headaches for 3 months. On examination, he was found to have a hairless fatty tissue nevus of the scalp (nevus psiloliparus), subcutaneous soft tissue masses on the right side of his face, neck, mandible and right buttock and epibulbar dermoid of the right eye (choristoma) (Figs. 1A, B). Magnetic resonance imaging revealed a large suprasellar mass, which was debulked and found to be a pilocytic astrocytoma. Testing was not performed for the BRAF/KIAA1549 fusion or BRAFV600E mutation...
April 20, 2018: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/29683881/gastric-type-adenocarcinoma-of-the-uterine-cervix-magnetic-resonance-imaging-features-clinical-outcomes-and-prognostic-factors
#12
Kye Jin Park, Mi-Hyun Kim, Jeong Kon Kim, Kyoung-Sik Cho
OBJECTIVE: Gastric-type mucinous adenocarcinoma (GAS) of uterine cervix has been suggested as distinct clinicopathologic behavior. Our study aimed to investigate the distinguishing imaging features and clinical outcomes of GAS. METHODS: Fifteen cases of GAS and 45 cases of 3:1 age-matched usual-type endocervical carcinoma (UEA) were assessed. Clinical parameters (age, tumor size, clinical stage, and time to recurrence [TTR] or death) and pathologic results confirmed by surgery were recorded...
April 21, 2018: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/29683879/patterns-of-recurrence-long-term-survival-and-toxicity-analysis-of-endometrial-adenocarcinoma-patients-reclassified-under-the-recent-esmo-esgo-estro-stratification-seven-year-results-from-a-single-institution
#13
Uday P Kumar, Prahlad H Yathiraj, Krishna T Sharan, Asha Kamath, Anshul Singh, S Anusha Reddy, Priyanka Alurkar, Donald J Fernandes, Vidyasagar S Mamidipudi
AIM: The aim of this study was to report the patterns of recurrence, locoregional control, and survival of patients diagnosed with endometrial adenocarcinomas over a 7-year period after reclassifying them under the recent ESMO-ESGO-ESTRO (European Society of Medical Oncology/European Society of Gynaecological Oncology/European Society for Radiotherapy and Oncology) consensus classification. METHODS: Archives of a single institution from 2008 to 2014 were studied and patients with stages I-II endometrial adenocarcinoma were reclassified as per the new classification for uniformity...
April 21, 2018: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/29683878/a-predictor-of-tumor-recurrence-in-patients-with-endometrial-carcinoma-after-complete-resection-of-the-tumor-the-role-of-pretreatment-apparent-diffusion-coefficient
#14
Ryo Kuwahara, Aki Kido, Shiro Tanaka, Kaoru Abiko, Kyoko Nakao, Yuki Himoto, Naoko Nishio, Yasuhisa Kurata, Masaki Mandai, Kaori Togashi
OBJECTIVES: The aim of this study was to assess the prognostic and incremental value of pretreatment apparent diffusion coefficient (ADC) values of tumors for the prediction of tumor recurrence after complete resection of the tumor in patients with endometrial cancer. METHODS: This study enrolled 210 patients with stages IA to IIIC endometrial cancer who had undergone complete resection of the tumor and pretreatment magnetic resonance imaging. The minimum and mean ADC values (ADCmin, ADCmean) of tumors and normalized ADC (nADCmin, nADCmean) were calculated from magnetic resonance imaging...
April 21, 2018: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/29683390/neural-correlates-of-speed-tuned-motion-perception-in-healthy-adults
#15
Kimberly Meier, Marita Partanen, Deborah Giaschi
It has been suggested that slow and medium-to-fast speeds of motion may be processed by at least partially separate mechanisms. The purpose of this study was to establish the cortical areas activated during motion-defined form and global motion tasks as a function of speed, using functional magnetic resonance imaging. Participants performed discrimination tasks with random dot stimuli at high coherence, at coherence near their own thresholds, and for random motion. Stimuli were moving at 0.1 or 5 deg/s. In the motion-defined form task, lateral occipital complex, V5/MT+ and intraparietal sulcus showed greater activation by high or near-threshold coherence than by random motion stimuli; V5/MT+ and intraparietal sulcus demonstrated greater activation for 5 than 0...
January 1, 2018: Perception
https://www.readbyqxmd.com/read/29683188/prediction-of-major-complications-after-hepatectomy-using-liver-stiffness-values-determined-by-magnetic-resonance-elastography
#16
N Sato, A Kenjo, T Kimura, R Okada, T Ishigame, Y Kofunato, T Shimura, K Abe, H Ohira, S Marubashi
BACKGROUND: Liver fibrosis is a risk factor for hepatectomy but cannot be determined accurately before hepatectomy because diagnostic procedures are too invasive. Magnetic resonance elastography (MRE) can determine liver stiffness (LS), a surrogate marker for assessing liver fibrosis, non-invasively. The aim of this study was to investigate whether the LS value determined by MRE is predictive of major complications after hepatectomy. METHODS: This prospective study enrolled consecutive patients who underwent hepatic resection between April 2013 and August 2016...
April 23, 2018: British Journal of Surgery
https://www.readbyqxmd.com/read/29683103/in-vivo-experiences-with-magnetic-resonance-imaging-scans-in-vibrant-soundbridge-type-503-implantees
#17
I Todt, P Mittmann, A Ernst, S Mutze, G Rademacher
OBJECTIVE: To observe the effects of magnetic resonance imaging scans in Vibrant Soundbridge 503 implantees at 1.5T in vivo. METHODS: In a prospective case study of five Vibrant Soundbridge 503 implantees, 1.5T magnetic resonance imaging scans were performed with and without a headband. The degree of pain was evaluated using a visual analogue scale. Scan-related pure tone audiogram and audio processor fitting changes were assessed. RESULTS: In all patients, magnetic resonance imaging scans were performed without any degree of pain or change in pure tone audiogram or audio processor fitting, even without a headband...
April 23, 2018: Journal of Laryngology and Otology
https://www.readbyqxmd.com/read/29683029/contrast-enhanced-fat-suppressed-flair-for-the-characterization-of-leptomeningeal-inflammation-in-optic-neuritis
#18
Luis Pino-Lopez, Holger Wenz, Johannes Böhme, Máté Maros, Frank Schlichtenbrede, Christoph Groden, Alex Förster
BACKGROUND: Leptomeningeal contrast enhancement on fluid-attenuated inversion recovery (FLAIR) images has been reported in patients with multiple sclerosis and interpreted as a biomarker of inflammation. In this study, we sought to evaluate this phenomenon in patients with optic neuritis (ON). METHODS: A total of 42 patients with suspected ON were included in this prospective study and underwent a dedicated study magnetic resonance imaging (MRI) protocol including native and contrast-enhanced fat-suppressed thin-section axial and coronal FLAIR images on an 1...
April 1, 2018: Multiple Sclerosis: Clinical and Laboratory Research
https://www.readbyqxmd.com/read/29682982/resection-of-medial-talocalcaneal-coalition-with-interposition-of-a-pediculated-flap-of-tibialis-posterior-tendon-sheath
#19
Jan Hubert, Thelonius Hawellek, Frank Timo Beil, Dominik Saul, Jens Henning Kling, Christoph Viebahn, Oliver Jungesblut, Ralf Stücker, Martin Rupprecht
BACKGROUND: The purpose of the study was to present a novel operative technique in the management of medial talocalcaneal coalition (TC) and to report our clinical and radiologic results after interposition of a pediculated flap (PF) of the tibialis posterior tendon sheath. METHODS: Twelve feet of 10 patients with a medial TC were treated with the interposition of PF of the tibialis posterior tendon sheath following resection. Pre- and postoperative clinical examinations were performed to evaluate the range of motion and the function of the tibialis posterior muscle of the affected foot...
April 1, 2018: Foot & Ankle International
https://www.readbyqxmd.com/read/29682905/novel-imaging-modalities-for-human-embryology-and-applications-in-education
#20
Shigehito Yamada, Shiori Nakano, Haruyuki Makishima, Tamaki Motoki
Advances in imaging technology and development have recently enabled high-resolution three-dimensional (3D) imaging of embryos and fetuses. Embryos and fetuses stored at the Congenital Anomaly Research Center (Kyoto Collection of Human Embryos, Kyoto, Japan) were imaged using multiple modalities including magnetic resonance imaging, episcopic fluorescence image capture, and X-ray computed tomography, both in absorption and phase-contrasted configurations. Using the acquired images, 3D computer graphics were generated and a movie was created to gain further insight into understanding the developmental process...
April 23, 2018: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
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