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https://www.readbyqxmd.com/read/29924746/exercise-training-mitigates-multi-system-deconditioning-during-bed-rest
#1
Lori L Ploutz-Snyder, Meghan Downs, Elizabeth Goetchius, Brent Crowell, Kirk L English, Robert Ploutz-Snyder, Jeffrey Ryder, E Lichar Dillon, Melinda Sheffield-Moore, Jessica M Scott
INTRODUCTION: This study investigated the safety and effectiveness of a new integrated aerobic and resistance exercise training prescription (SPRINT) using two different sets of exercise equipment: a suite of large ISS-like exercise equipment similar to what is found on the International Space Station (ISS) and a single device with aerobic and resistance exercise capability in the spaceflight analog of bed rest (BR). METHODS: Subjects (n=34) completed 70 days of 6° head down tilt BR: 9 were randomized to remain sedentary (CONT), 9 to exercise training using traditional equipment (EX), 8 to exercise using traditional equipment and low dose testosterone supplementation (ExT), and 8 to exercise using a combined resistance and aerobic flywheel device (FLY)...
March 26, 2018: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29924716/tumor-surface-regularity-at-mr-imaging-predicts-survival-and-response-to-surgery-in-patients-with-glioblastoma
#2
Julián Pérez-Beteta, David Molina-García, José A Ortiz-Alhambra, Antonio Fernández-Romero, Belén Luque, Elena Arregui, Manuel Calvo, José M Borrás, Bárbara Meléndez, Ángel Rodríguez de Lope, Raquel Moreno de la Presa, Lidia Iglesias Bayo, Juan A Barcia, Juan Martino, Carlos Velásquez, Beatriz Asenjo, Manuel Benavides, Ismael Herruzo, Antonio Revert, Estanislao Arana, Víctor M Pérez-García
Purpose To evaluate the prognostic and predictive value of surface-derived imaging biomarkers obtained from contrast material-enhanced volumetric T1-weighted pretreatment magnetic resonance (MR) imaging sequences in patients with glioblastoma multiforme. Materials and Methods A discovery cohort from five local institutions (165 patients; mean age, 62 years ± 12 [standard deviation]; 43% women and 57% men) and an independent validation cohort (51 patients; mean age, 60 years ± 12; 39% women and 61% men) from The Cancer Imaging Archive with volumetric T1-weighted pretreatment contrast-enhanced MR imaging sequences were included in the study...
July 2018: Radiology
https://www.readbyqxmd.com/read/29924654/clinical-significance-of-incidental-pituitary-tc-99m-mibi-uptake-on-parathyroid-spect-and-factors-affecting-uptake-intensity
#3
Mine Araz, Derya Cayir, Bekir Ucan, Alper Dilli, Erman Çakal
OBJECTIVE: (1)To define a quantitative cutoff value for incidental pituitary Technetium-99m methoxyisobutylisonitrile (Tc-99m MIBI) uptake above which is of clinical importance and (2) to investigate possible factors affecting the intensity of uptake in pituitary adenoma. MATERIALS AND METHODS: A retrospective analysis of 55 patients with a simultaneous parathyroid single-photon emission computed tomography and pituitary magnetic resonance imaging were included...
June 20, 2018: Cancer Biotherapy & Radiopharmaceuticals
https://www.readbyqxmd.com/read/29924644/investigating-the-intersession-reliability-of-dynamic-brain-state-properties
#4
Derek M Smith, Yrian Zhao, Shella D Keilholz, Eric H Schumacher
Dynamic functional connectivity metrics have much to offer to the neuroscience of individual differences of cognition. Yet, despite the recent expansion in dynamic connectivity research, limited resources have been devoted to the study of the reliability of these connectivity measures. To address this, resting-state functional magnetic resonance imaging data from 100 Human Connectome Project subjects were compared across 2 scan days. Brain states (i.e., patterns of coactivity across regions) were identified by classifying each time frame using k means clustering...
June 2018: Brain Connectivity
https://www.readbyqxmd.com/read/29924633/an-intra-articular-steroid-injection-at-6-weeks-postoperatively-for-shoulder-stiffness-after-arthroscopic-rotator-cuff-repair-does-not-affect-repair-integrity
#5
In-Bo Kim, Dong Wook Jung
BACKGROUND: Shoulder stiffness is a common complication after arthroscopic rotator cuff repair. However, there is no consensus on the treatment of stiffness after repair. Although one treatment option is an intra-articular steroid injection, it may negatively affect repair integrity, and there is a paucity of literature regarding the timing of intra-articular injections for stiffness after repair and its effect on repair integrity. PURPOSE: To compare repair integrity and clinical outcomes after an intra-articular steroid injection administered at 6 weeks and 12 weeks postoperatively for shoulder stiffness after arthroscopic rotator cuff repair...
June 1, 2018: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29924326/functional-connectivity-of-the-raphe-nuclei-link-to-tobacco-withdrawal-in-smokers
#6
Paul Faulkner, Dara G Ghahremani, Rachel F Tyndale, Gerhard Hellemann, Edythe D London
Background: Although nicotine alters serotonergic neurochemistry, clinical trials of serotonergic medications for smoking cessation have provided mixed results. Understanding the role of serotonergic dysfunction in tobacco use disorder may advance development of novel pharmacotherapies. Methods: Functional magnetic resonance imaging was used to measure resting-state functional connectivity of the raphe nuclei as an indicator of serotonergic function. Connectivity of the dorsal and median raphe nuclei was compared between 18 young smokers (briefly-abstinent, ~40 minutes post-smoking) and 19 young non-smokers (16-21 years old); connectivity was also examined in a separate sample of overnight-abstinent smokers (18-25 years old), before and after smoking the first cigarette of the day...
June 19, 2018: International Journal of Neuropsychopharmacology
https://www.readbyqxmd.com/read/29924294/fat-label-compared-with-fat-content-gastrointestinal-symptoms-and-brain-activity-in-functional-dyspepsia-patients-and-healthy-controls
#7
In-Seon Lee, Stephanie Kullmann, Klaus Scheffler, Hubert Preissl, Paul Enck
Background: High-fat meals are associated with dyspeptic symptoms in functional dyspepsia (FD) patients. It is still unclear how fat is processed, or how FD symptoms and neuronal activities are modulated by psychological factors. Objective: We investigated brain activity by functional magnetic resonance imaging (fMRI) after the ingestion of high- and low-fat foods with correct/incorrect fat information. Design: We compared 12 FD patients and 14 healthy controls (HCs)...
June 18, 2018: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29924047/lumbar-spinal-canal-osteosarcoma-a-case-report
#8
De-Jian Chen, Qi Lai, Jianghao Zhu, Zongmiao Wan, Hucheng Liu, Min Dai, Runsheng Guo, Bin Zhang
RATIONALE: Osteosarcoma is a rare neoplasm in the lumbar spine. Although osteosarcoma can arise in any portion of the skeleton, it very rarely arises in the spinal canal, which accounts for <0.1% of all cases of adult sarcomas. Here, we describe a case of osteosarcoma arising in the L4-5 spinal canal. PATIENT CONCERNS: The present report describes the case of a 55-year-old female patient with osteosarcoma of the L4-5 spinal canal. DIAGNOSES: The patient was initially diagnosed with lumbar spinal stenosis and underwent lumbar fusion at a local hospital...
June 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29924027/alveolar-paratesticular-rhabdomyosarcoma-mimicing-epididymitis-case-report-and-literature-review
#9
W-H Lei, Wen-Feng Wu, Jin-Yang Zhen, Yang-Hui Li, Jie Li, Jun Xin
RATIONALE: Most patients with paratesticular rhabdomyosarcoma may typically present as a unilateral, painless palpable scrotum mass. However, only a few cases of RMS presenting as painful edema of the scrotum mimicing epididymitis. We herein report an unusual case of alveolar paratesticular rhabdomyosarcoma misdiagnosed as epididymitis. PATIENT CONCERNS: A 19-year-old adolescent, presented to urologist with painful swelling of the scrotum on the left side over the preceding several days...
June 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29924004/diffuse-giant-cell-tumors-of-the-tendon-sheath-in-temporomandibular-joint-two-case-reports-and-review-of-the-literature
#10
Hong Yan, Furong Wang, Lin Xiang, Wei Zhu, Cheng Liang
RATIONALE: Diffuse giant cell tumors of the tendon sheath (GCT-TS) in the temporomandibular joint (TMJ) are extremely rare. PATIENT CONCERNS: We reported the imaging appearance and the pathological findings of 2 male cases with diffuse GCT-TS in the TMJ (52 years for the case 1 and 50 years for the case 2) who complain of the hearing disorders of left ear when presenting to our hospital. DIAGNOSIS: Preoperative computerized tomography (CT) scan revealed an irregular mass in the left temporal fossa with the sizes of approximately 5...
June 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29924003/predictability-of-severity-of-disc-degeneration-and-disc-protrusion-using-horizontal-displacement-of-cervical-dynamic-radiographs-a-retrospective-comparison-study-with-mri
#11
Chul-Hyun Kim, Jong Moon Hwang, Jin-Sung Park, Seungwoo Han, Donghwi Park
The aim of this study is to investigate the usefulness of flexion-extension (dynamic) radiographs in evaluating the severity of disc degeneration and disc protrusion in cervical magnetic resonance image (MRI). Patients complaining of neck or arm pain with no prior surgical history and who had undergone both cervical MRI and dynamic radiographs were included in this study. The following patients were excluded: those who had any history of trauma, autoimmune disease such as rheumatoid arthritis or ankylosing spondylitis, prior cervical fracture or prior cervical spine surgery...
June 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29923998/clinical-study-on-postoperative-triple-negative-breast-cancer-with-chinese-medicine-study-protocol-for-an-observational-cohort-trial
#12
Jiajing Chen, Yuenong Qin, Chenping Sun, Wei Hao, Shuai Zhang, Yi Wang, Juan Chen, Lixin Chen, Yiying Ruan, Sheng Liu
BACKGROUND: Breast cancer (BC) poses a tremendous threat to the health of women worldwide, especially triple-negative breast cancers (TNBCs). Currently, the curative effect of traditional Chinese medicine (TCM) has been recognized in more and more people worldwide; however, the specific effect has not been systematically evaluated. The purpose of this cohort study is to evaluate the clinical effects of TCM syndrome differentiation on recurrence and metastasis rate, survival rate, and the quality of life in patients with TNBC...
June 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29923988/coexistence-of-double-gallbladder-with-cholangiocarcinoma-a-case-report
#13
Wei Chen, Ruoling Han
RATIONALE: Gallbladder duplication is a rare congenital disorder, which could cause an increasing risk of complications during surgery. The coexistence of cholangiocarcinoma with double gallbladder is extremely rare, which might lead to an even higher possibility of misdiagnosis and postsurgery complications. PATIENT CONCERNS: A 58-year-old female was presented with abdominal pain and jaundice. Abdominal ultrasonography showed duplication of gallbladder, one of which with a thickened wall and a rough surface...
June 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29923985/tarsal-tunnel-syndrome-caused-by-an-uncommon-ossicle-of-the-talus-a-case-report
#14
Chang Hwa Hong, Young Koo Lee, Sung Hun Won, Dhong Won Lee, Sang Il Moon, Woo Jong Kim
RATIONALE: Tarsal tunnel syndrome (TTS) is a compressive neuropathy of the posterior tibial nerve or one of its branches within the tarsal tunnel that is often caused by a variety of space-occupying lesions, such as ganglia, lipomas, varicosities, neural tumors, trauma, or systemic disease. The os sustentaculi is a small accessory bone, bridged to the posterior aspect of the sustentaculum tali by fibrocartilage. To the best of our knowledge, this is a rare case of successful treatment of TTS caused by the os sustantaculi...
June 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29923949/hypertonic-sodium-chloride-preinjectate-increases-in-vivo-radiofrequency-ablation-size-histological-and-magnetic-resonance-imaging-findings
#15
David A Provenzano, Eric R Cosman, Jared T Wilsey
BACKGROUND AND OBJECTIVES: Emphasis has been placed on methods to enlarge monopolar radiofrequency (RF) lesion size for pain management. Ex vivo research has suggested that fluid modulation may be an effective method to enlarge lesion zone. To date, these findings have not been confirmed in vivo. The purpose of this study was to determine the effect of hypertonic saline on in vivo lesion size through both histological and magnetic resonance imaging (MRI) analysis. A secondary purpose was to validate in vivo characterization of RF lesions using contrast-enhanced MRI...
June 19, 2018: Regional Anesthesia and Pain Medicine
https://www.readbyqxmd.com/read/29923345/detection-of-prostate-cancer-with-multiparametric-mri-utilizing-the-anatomic-structure-of-the-prostate
#16
Jin Jin, Lin Zhang, Ethan Leng, Gregory J Metzger, Joseph S Koopmeiners
Multiparametric magnetic resonance imaging (mpMRI), which combines traditional anatomic and newer quantitative MRI methods, has been shown to result in improved voxel-wise classification of prostate cancer as compared with any single MRI parameter. While these results are promising, substantial heterogeneity in the mpMRI parameter values and voxel-wise prostate cancer risk has been observed both between and within regions of the prostate. This suggests that classification of prostate cancer can potentially be improved by incorporating structural information into the classifier...
June 19, 2018: Statistics in Medicine
https://www.readbyqxmd.com/read/29923157/cmr-guidance-of-passively-tracked-endomyocardial-biopsy-in-an-in-vivo-porcine-model
#17
P Behm, M Gastl, A Jahn, A Rohde, S Haberkorn, S Krueger, S Weiss, B Schnackenburg, M Sager, K Düring, H Clogenson, P Horn, R Westenfeld, M Kelm, M Neizel-Wittke, F Bönner
Endomyocardial biopsy (EMB) is considered to be the diagnostic gold-standard in detection of myocardial-inflammation. EMB is usually conducted under fluoroscopy without any specific target information. Specific target-information provided by cardiovascular magnetic resonance (CMR) may improve specificity of EMB. The aim was to investigate feasibility and safety of CMR-guided and targeted EMB in a preclinical-model using passively-tracked devices. Procedures were performed on a MRI-System equipped with an Interventional Software-Platform for real-time imaging...
June 19, 2018: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/29923098/does-intrinsic-reward-motivate-cognitive-control-a-naturalistic-fmri-study-based-on-the-synchronization-theory-of-flow
#18
Richard Huskey, Britney Craighead, Michael B Miller, René Weber
Cognitive control is a framework for understanding the neuropsychological processes that underlie the successful completion of everyday tasks. Only recently has research in this area investigated motivational contributions to control allocation. An important gap in our understanding is the way in which intrinsic rewards associated with a task motivate the sustained allocation of control. To address this issue, we draw on flow theory, which predicts that a balance between task difficulty and individual ability results in the highest levels of intrinsic reward...
June 19, 2018: Cognitive, Affective & Behavioral Neuroscience
https://www.readbyqxmd.com/read/29923073/perioperative-platelet-rich-plasma-prp-in-total-hip-arthroplasty-through-the-hardinge-approach-protocol-to-study-the-effectiveness-for-gluteus-medius-healing
#19
Anni Aavikko, J Puhakka, J Haapala, J Kukkonen, K Mäkelä, J Kosola
BACKGROUND: Platelet-rich plasma (PRP) has been used to support tendon regeneration mainly in sports medicine. PRP is a concentrate of platelet-rich plasma proteins derived from whole blood by centrifugation to remove erythrocytes and leukocytes. PRP has high amounts of platelets which may promote healing tendons affected by degenerative conditions. These platelets contain growth factors and are known to facilitate the regeneration of injured tendon structures. Total hip arthroplasty (THA) through the Hardinge approach may leave the patient with impaired gait and poor regeneration of the gluteus medius tendon if the tendon is not reattached properly after closure of the surgical wound...
June 19, 2018: Journal of Experimental Orthopaedics
https://www.readbyqxmd.com/read/29923022/wide-slab-is-useful-for-routine-quality-control-of-mri-slice-thickness
#20
Yoshiyuki Ishimori, Masahiko Monma, Hiraku Kawamura
Although slice thickness accuracy is important for the performance of magnetic resonance imaging systems, long scan times are required to perform reliable measurements. Inclined slabs and wedges are conventionally used as test devices to obtain slice profiles. In this study, a novel dedicated device with a widened slab was created, and its efficacy was compared with that of a conventional wedge. The signal-to-noise ratio (SNR) of the profile and the coefficient of variation (CV) of the measured slice thickness were measured...
June 19, 2018: Radiological Physics and Technology
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