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https://www.readbyqxmd.com/read/28725300/epstein-barr-virus-ebv-associated-epithelial-and-non-epithelial-lesions-of-the-oral-cavity
#1
REVIEW
Kentaro Kikuchi, Harumi Inoue, Yuji Miyazaki, Fumio Ide, Masaru Kojima, Kaoru Kusama
Epstein-Barr virus (EBV) is known to be associated with the development of malignant lymphoma and lymphoproliferative disorders (LPDs) in immunocompromised patients. EBV, a B-lymphotropic gamma-herpesvirus, causes infectious mononucleosis and oral hairy leukoplakia, as well as various pathological types of lymphoid malignancy. Furthermore, EBV is associated with epithelial malignancies such as nasopharyngeal carcinoma (NPC), salivary gland tumor, gastric carcinoma and breast carcinoma. In terms of oral disease, there have been several reports of EBV-related oral squamous cell carcinoma (OSCC) worldwide...
August 2017: Japanese Dental Science Review
https://www.readbyqxmd.com/read/28725293/traditional-medicine-as-a-potential-treatment-for-flammer-syndrome
#2
Akiko Kikuchi, Yukihiro Shiga, Shin Takayama, Ryutaro Arita, Shigeto Maekawa, Soichiro Kaneko, Noriko Himori, Tadashi Ishii, Toru Nakazawa
No abstract text is available yet for this article.
June 2017: EPMA Journal
https://www.readbyqxmd.com/read/28724766/a-unique-t-cell-receptor-amino-acid-sequence-selected-by-htlv-i-tax301-309-specific-cytotoxic-t-cells-in-hla-a24-02-asymptomatic-carriers-and-adult-t-cell-leukemia-lymphoma-patients
#3
Yuko Ishihara, Yukie Tanaka, Seiichiro Kobayashi, Koji Kawamura, Hideki Nakasone, Ayumi Gomyo, Jin Hayakawa, Masaharu Tamaki, Yu Akahoshi, Naonori Harada, Machiko Kusuda, Kazuaki Kameda, Tomotaka Ugai, Hidenori Wada, Kana Sakamoto, Miki Sato, Kiriko Terasako-Saito, Misato Kikuchi, Shun-Ichi Kimura, Aki Tanihara, Shinichi Kako, Kaoru Uchimaru, Yoshinobu Kanda
We previously reported that the T-cell receptor (TCR) repertoire of HTLV-I Tax301-309-specific CD8(+) cytotoxic T-cells (Tax-CTLs) was highly restricted and a particular amino acid sequence motif, "PDR", was conserved among HLA-A*24:02(+) ATL patients who have undergone allogeneic hematopoietic cell transplantation (allo-HSCT). Furthermore, we found that donor-derived PDR+CTLs selectively expanded in ATL long-term HSCT survivors with strong CTL activity against HTLV-I. On the other hand, the TCR repertoires in Tax-CTL of asymptomatic HTLV-I carriers (ACs) remain unclear...
July 19, 2017: Journal of Virology
https://www.readbyqxmd.com/read/28721279/age-related-circadian-disorganization-caused-by-sympathetic-dysfunction-in-peripheral-clock-regulation
#4
Yu Tahara, Yuta Takatsu, Takuya Shiraishi, Yosuke Kikuchi, Mayu Yamazaki, Hiroaki Motohashi, Aya Muto, Hiroyuki Sasaki, Atsushi Haraguchi, Daisuke Kuriki, Takahiro J Nakamura, Shigenobu Shibata
The ability of the circadian clock to adapt to environmental changes is critical for maintaining homeostasis, preventing disease, and limiting the detrimental effects of aging. To date, little is known about age-related changes in the entrainment of peripheral clocks to external cues. We therefore evaluated the ability of the peripheral clocks of the kidney, liver, and submandibular gland to be entrained by external stimuli including light, food, stress, and exercise in young versus aged mice using in vivo bioluminescence monitoring...
2017: NPJ Aging and Mechanisms of Disease
https://www.readbyqxmd.com/read/28720684/fsgs-as-an-adaptive-response-to-growth-induced-podocyte-stress
#5
Ryuzoh Nishizono, Masao Kikuchi, Su Q Wang, Mahboob Chowdhury, Viji Nair, John Hartman, Akihiro Fukuda, Larysa Wickman, Jeffrey B Hodgin, Markus Bitzer, Abhijit Naik, Jocelyn Wiggins, Matthias Kretzler, Roger C Wiggins
Glomerular sclerotic lesions develop when the glomerular filtration surface area exceeds the availability of podocyte foot process coverage, but the mechanisms involved are incompletely characterized. We evaluated potential mechanisms using a transgenic (podocin promoter-AA-4E-BP1) rat in which podocyte capacity for hypertrophy in response to growth factor/nutrient signaling is impaired. FSGS lesions resembling human FSGS developed spontaneously by 7 months of age, and could be induced earlier by accelerating kidney hypertrophy by nephrectomy...
July 18, 2017: Journal of the American Society of Nephrology: JASN
https://www.readbyqxmd.com/read/28718620/high-performance-cathode-based-on-microporous-mo-v-bi-oxide-for-li-battery-and-the-investigation-by-operando-x-ray-absorption-fine-structure
#6
Zhenxin Zhang, Satoshi Ishikawa, Masaki Kikuchi, Hirofumi Yoshikawa, Qi Lian, Heng Wang, Toshiaki Ina, Akihiro Yoshida, Masahiro Sadakane, Futoshi Matsumoto, Wataru Ueda
The development of cathode-active material of Li battery is important for the current emerging energy transferring and saving problems. A stable crystalline microporous complex metal oxide based on Mo, V, and Bi is an active and suitable material for Li battery. High capacity (380 Ah/kg) and stable cycle performance are achieved. X-ray absorption near-edge structure analyses demonstrate that the original Mo(6+) and V(4+) ions are reduced to Mo(4+) and V(3+) in the dis-charging process, respectively, which results in a 70-electron reduction per formula...
July 18, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28709124/we-could-predict-good-responders-to-vagus-nerve-stimulation-a-surrogate-marker-by-slow-cortical-potential-shift
#7
Borgil Bayasgalan, Masao Matsuhashi, Tomoyuki Fumuro, Haruhiko Nohira, Naoki Nakano, Koji Iida, Masaya Katagiri, Akihiro Shimotake, Riki Matsumoto, Takayuki Kikuchi, Takeharu Kunieda, Amami Kato, Ryosuke Takahashi, Akio Ikeda
OBJECTIVE: We investigated whether vagus nerve stimulation (VNS) induces a positive shift of slow cortical potentials (SCPs) in patients with >50% seizure reduction (responders) but not in non-responders. METHODS: We analyzed routine clinical electroencephalograms (EEGs) from 24 patients who were undergoing seizure treatment by VNS. The patients were divided into 2 groups by hardware time constant (TC) of EEG: the TC 10-s group (10 patients) and TC 2-s group (14 patients)...
June 15, 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/28708793/patulous-eustachian-tube-and-otitis-media-with-effusion-as-complications-after-trigeminal-nerve-injury
#8
Ryoukichi Ikeda, Toshimitsu Kobayashi, Masayuki Yoshida, Naohiro Yoshida, Toshiaki Kikuchi, Takeshi Oshima, Tetsuaki Kawase, Yukio Katori
OBJECTIVES: To describe three patients of patulous Eustachian tube (pET) after trigeminal nerve injury and to demonstrate for the first time their magnetic resonance imaging (MRI) findings to hypothesize the mechanism of the pET after trigeminal nerve injury. PATIENTS: Three patients presented with autophony after trigeminal nerve injury caused by the removal of intracranial tumors. MAIN OUTCOME MEASURES: Clinical patient records, audiological data, and MRI...
July 13, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28706345/a-fischer-indolization-strategy-toward-the-total-synthesis-of-goniomitine
#9
Beau P Pritchett, Jun Kikuchi, Yoshitaka Numajiri, Brian M Stoltz
A Fischer indolization strategy toward the core of (-)-goniomitine is reported. Initial investigations into the Pd-catalyzed asymmetric allylic alkylation of dihydropyrido[1,2-a]indolone (DHPI) substrates are also discussed.
2017: Heterocycles
https://www.readbyqxmd.com/read/28695437/quantitative-aspects-of-communicative-impairment-ascertained-in-a-large-national-survey-of-japanese-children
#10
Manabu Oi, Hiroshi Fujino, Naotake Tsukidate, Yoko Kamio, Yuko Yoshimura, Mitsuru Kikuchi, Chiaki Hasegawa, Keiko Gondou, Tomoko Matsui
The Japanese version of the Children's Communication Checklist-2 (CCC-2) was rated by caregivers in a large national population sample of 22,871 children aged 3-15 years. The General Communication Composite (GCC) of the CCC-2 exhibited a distribution with a single-factor structure. The GCC distribution between autism spectrum disorders (ASD) and language impairment (LI) groups in the general population fit inside a bell curve with significant overlap with the general population, and a continuum was evident between groups...
July 10, 2017: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/28695380/macular-capillary-recovery-in-systemic-lupus-erythematosus-complicated-by-kikuchi-fujimoto-disease
#11
Reiko Kinouchi, Motoshi Kinouchi, Akihiro Ishibazawa, Akitoshi Yoshida
PURPOSE: Few case reports have described vaso-occlusive retinopathy in systemic lupus erythematosus (SLE) using optical coherence tomography (OCT) angiography. Here we report the clinical features of a patient with SLE, complicated by Kikuchi-Fujimoto disease, who developed vaso-occlusive retinopathy. We then describe the subsequent recovery of the macular capillaries as assessed by OCT angiography. CASE: A 16-year-old male was referred to us with fever, a 1-month history of violaceous red papules and erythematous plaques on his face and a painful nodule in his right neck...
July 10, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28695266/erratum-to-is-there-any-benefit-using-low-intensity-inspiratory-and-peripheral-muscle-training-in-heart-failure-a-randomized-clinical-trial
#12
Tatiana Satie Kawauchi, Iracema Ioco Kikuchi Umeda, Lays Magalhães Braga, Antonio de Pádua Mansur, João Manoel Rossi-Neto, Amanda Guerra de Moraes Rego Sousa, Mário Hiroyuki Hirata, Lawrence P Cahalin, Naomi Kondo Nakagawa
No abstract text is available yet for this article.
July 10, 2017: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/28693162/kikuchi-fujimoto-disease-in-the-regional-lymph-nodes-with-node-metastasis-in-a-patient-with-tongue-cancer-a-case-report-and-literature-review
#13
Tessho Maruyama, Kazuhide Nishihara, Masanao Saio, Toshiyuki Nakasone, Fumikazu Nimura, Akira Matayoshi, Takahiro Goto, Naoki Yoshimi, Akira Arasaki
Kikuchi-Fujimoto disease (KFD), also known as histiocytic necrotizing lymphadenitis, is a rare self-limiting disorder typically affecting the cervical lymph nodes (LNs), which is often misdiagnosed as other LN-associated diseases. KFD frequently presents with necrotic lesions and recurrences, which are also features of metastatic LNs. Clinicians may thus suspect LN metastasis when they encounter ipsilateral cervical lymphadenopathy in a patient with head and neck cancer. The present study reports the case of a 48-year-old man with tongue cancer and KFD affecting the right edge of his tongue and ipsilateral cervical LNs...
July 2017: Oncology Letters
https://www.readbyqxmd.com/read/28692706/predictors-for-bile-duct-stone-recurrence-after-endoscopic-extraction-for-na%C3%A3-ve-major-duodenal-papilla-a-cohort-study
#14
Shin Kato, Kenji Chinen, Susumu Shinoura, Kaoru Kikuchi
BACKGROUND: Predictors for bile duct stone recurrence after endoscopic stone extraction have not yet been clearly defined and a study investigating naïve major duodenal papilla is warranted because studies focusing only on naïve major duodenal papilla are rare. The aim of this study was to observe the long-term outcomes of endoscopic bile duct stone extraction for naïve major duodenal papilla and to assess the predictors for recurrence. METHODS: This was a retrospective cohort study that consisted of 384 patients with naïve papilla who underwent initial endoscopic bile duct stone extraction...
2017: PloS One
https://www.readbyqxmd.com/read/28687947/species-of-tetrancistrum-goto-kikuchi-1917-monogenea-dactylogyridae-from-the-gills-of-the-whitespotted-rabbitfish-siganus-canaliculatus-park-perciformes-siganidae-off-omani-coasts-with-a-description-of-tetrancistrum-labyrinthus-n-sp
#15
Sarah H Al Jufaili, Harry W Palm
Tetrancistrum labyrinthus n. sp. is described from the gills of the marine herbivorous fish Siganus canaliculatus (Park) found in the Western Indian Ocean (Sea of Oman and Arabian Sea). Comparative morphological analyses of all previously described species of Tetrancistrum Goto & Kikuchi, 1917 confirmed the distinct status of T. labyrinthus n. sp. The new species closely resembles T. suezicum Paperna, 1972 and T. oraminii Young, 1967 in the morphology of the male copulatory organ. However, it can be distinguished by possessing a thin handle-like anterior basal flange and a compound accessory piece that is composed of a tapering rod-shaped anterior part and a large cylindrical, elongated posterior part...
July 7, 2017: Systematic Parasitology
https://www.readbyqxmd.com/read/28687783/serum-tff1-and-tff3-but-not-tff2-are-higher-in-women-with-breast-cancer-than-in-women-without-breast-cancer
#16
Yuko Ishibashi, Hiroshi Ohtsu, Masako Ikemura, Yasuko Kikuchi, Takayoshi Niwa, Kotoe Nishioka, Yoshihiro Uchida, Hirona Miura, Susumu Aikou, Toshiaki Gunji, Nobuyuki Matsuhashi, Yasukazu Ohmoto, Takeshi Sasaki, Yasuyuki Seto, Toshihisa Ogawa, Keiichiro Tada, Sachiyo Nomura
Breast cancer remains a common malignancy in women, but the take-up for breast cancer screening programs in Japan is still low, possibly due to its perceived inconvenience. TFF1 and TFF3 are expressed in both breast cancer tissue and normal breast. Serum trefoil proteins were reported as cancer screening markers for gastric, prostate, lung, pancreatic cancer and cholangio carcinoma. The purpose of this study was to examine whether serum trefoil proteins could be screening biomarkers for breast cancer. Serum trefoil proteins in 94 breast cancer patients and 84 health check females were measured by ELISA...
July 7, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28687738/a-possible-origin-population-of-pathogenic-intestinal-nematodes-strongyloides-stercoralis-unveiled-by-molecular-phylogeny
#17
Eiji Nagayasu, Myo Pa Pa Thet Hnin Htwe Aung, Thanaporn Hortiwakul, Akina Hino, Teruhisa Tanaka, Miwa Higashiarakawa, Alex Olia, Tomoyo Taniguchi, Soe Moe Thu Win, Isao Ohashi, Emmanuel Igwaro Odongo-Aginya, Khin Myo Aye, Mon Mon, Kyu Kyu Win, Kei Ota, Yukari Torisu, Siripen Panthuwong, Eisaku Kimura, Nirianne M Q Palacpac, Taisei Kikuchi, Tetsuo Hirata, Shidow Torisu, Hajime Hisaeda, Toshihiro Horii, Jiro Fujita, Wah Win Htike, Haruhiko Maruyama
Humans and dogs are the two major hosts of Strongyloides stercoralis, an intestinal parasitic nematode. To better understand the phylogenetic relationships among S. stercoralis isolates infecting humans and dogs and to assess the zoonotic potential of this parasite, we analyzed mitochondrial Cox1, nuclear 18S rDNA, 28S rDNA, and a major sperm protein domain-containing protein genes. Overall, our analyses indicated the presence of two distinct lineages of S. stercoralis (referred to as type A and type B). While type A parasites were isolated both from humans and dogs in different countries, type B parasites were found exclusively in dogs, indicating that the type B has not adapted to infect humans...
July 7, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28686315/pentalogy-of-cantrell-in-a-monozygotic-twin-with-a-giant-omphalocele-firmly-attached-to-the-amniotic-membrane-successful-prenatal-diagnosis-and-cesarean-delivery
#18
Tomonobu Kanasugi, Akihiko Kikuchi, Noriyuki Uesugi, Daisuke Fukagawa, Hideyuki Chida, Yuri Sasaki, Gen Haba, Chizuko Isurugi, Rie Oyama, Tamotsu Sugai, Toru Sugiyama
No abstract text is available yet for this article.
July 7, 2017: Congenital Anomalies
https://www.readbyqxmd.com/read/28685822/thalamic-connections-of-the-core-auditory-cortex-and-rostral-supratemporal-plane-in-the-macaque-monkey
#19
Brian H Scott, Kadharbatcha S Saleem, Yukiko Kikuchi, Makoto Fukushima, Mortimer Mishkin, Richard C Saunders
In the primate auditory cortex, information flows serially in the mediolateral dimension from core, to belt, to parabelt. In the caudorostral dimension, stepwise serial projections convey information through the primary, rostral, and rostrotemporal (AI, R, and RT) core areas on the supratemporal plane (STP), continuing to the rostrotemporal polar area (RTp) and adjacent auditory-related areas of the rostral superior temporal gyrus (STGr) and temporal pole. In addition to this cascade of corticocortical connections, the auditory cortex receives parallel thalamocortical projections from the medial geniculate nucleus (MGN)...
July 7, 2017: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/28685308/pseudo-autologous-stem-cell-transplantation-for-donor-derived-mantle-cell-lymphoma-12%C3%A2-years-after-allogeneic-transplantation
#20
Masaharu Tamaki, Hidenori Wada, Ayumi Gomyo, Jin Hayakawa, Yu Akahoshi, Naonori Harada, Machiko Kusuda, Yuko Ishihara, Koji Kawamura, Aki Tanihara, Miki Sato, Kiriko Terasako-Saito, Kazuaki Kameda, Misato Kikuchi, Shun-Ichi Kimura, Hideki Nakasone, Shinichi Kako, Yoshinobu Kanda
Donor-derived malignancy is a rare morbidity after allogeneic hematopoietic stem cell transplantation (HSCT), in which most previous cases have presented as acute leukemia or myelodysplastic syndrome. There have, however, been very few reports of donor-derived lymphoma. Here, we present a case of donor-derived mantle cell lymphoma 12 years after allogeneic HSCT, which was successfully treated with chemotherapy followed by pseudo-autologous HSCT (pASCT), i.e., an autologous HSC transplant following allogeneic HSCT in which the infused stem cell is considered to be derived from the donor cells...
July 6, 2017: International Journal of Hematology
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