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Six minutes walk test

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https://www.readbyqxmd.com/read/28340403/micro-and-macrovascular-function-in-children-with-sickle-cell-anaemia-and-sickle-cell-haemoglobin-c-disease
#1
Berenike Möckesch, Keyne Charlot, Stéphane Jumet, Marc Romana, Lydia Divialle-Doumdo, Marie-Dominique Hardy-Dessources, Marie Petras, Benoît Tressieres, Vanessa Tarer, Olivier Hue, Maryse Etienne-Julan, Philippe Connes, Sophie Antoine-Jonville
It is unclear whether vascular function is affected similarly in children with sickle cell anaemia (SS) and children with sickle haemoglobin C (SC) disease. Therefore, we compared micro and macrovascular functions in healthy (AA) children, children with SS and SC disease, and assessed their association with physical activity. Participants (24 SS, 22 SC and 16 AA), were compared in terms of 1) thermal hyperaemic response (finger pad warming to 42°C) measured by Laser Doppler techniques, 2) arterial stiffness determined by pulse wave velocity, 3) daily energy expenditure related to moderate and intense physical activities estimated by questionnaire and 4) fitness level, evaluated by the six-minute walk test...
February 4, 2017: Blood Cells, Molecules & Diseases
https://www.readbyqxmd.com/read/28340285/the-six-minute-walk-test-in-patients-with-al-amyloidosis-a-single-centre-case-series
#2
Vina Pulido, Gheorghe Doros, John L Berk, Vaishali Sanchorawala
The six-minute walk test (6MWT) has been widely used as an objective evaluation of functional exercise capacity and response to medical intervention in cardiopulmonary diseases. However, little is known about the 6MWT in evaluating patients with AL amyloidosis. We performed a retrospective study of 120 adults with systemic AL amyloidosis (60 with cardiac involvement and 60 without cardiac involvement) who had their initial evaluation at the Amyloidosis Center between 2013 and 2015 and had undergone 6MWT as a measure of functional exercise capacity...
March 24, 2017: British Journal of Haematology
https://www.readbyqxmd.com/read/28336345/dancing-for-parkinson-s-a-randomized-trial-of-irish-set-dancing-compared-to-usual-care
#3
Joanne Shanahan, Meg E Morris, Orfhlaith Ni Bhriain, Daniele Volpe, Tim Lynch, Amanda M Clifford
OBJECTIVE: This pilot trial examined the feasibility of a randomised controlled study design and explored the benefits of the set dancing intervention compared to usual care. DESIGN: Randomised controlled design, with participants randomised to Irish set dance classes or a usual care control group. SETTING: Community based PARTICIPANTS: Individuals with idiopathic PD INTERVENTIONS: The dance group attended a 1.5 hour dancing class each week for 10 weeks and undertook a home dance programme for 20 minutes three times per week...
March 21, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28323361/heart-rate-variability-parameters-in-horses-distinguish-atrial-fibrillation-from-sinus-rhythm-before-and-after-successful-electrical-cardioversion
#4
B Broux, D De Clercq, A Decloedt, S Ven, L Vera, G van Steenkiste, K Mitchell, C Schwarzwald, G van Loon
BACKGROUND: Atrial fibrillation (AF) is the most common pathological arrhythmia in horses. After successful treatment, recurrence is common. Heart rate monitors are easily applicable in horses and some devices offer basic heart rate variability (HRV) calculations. If HRV can be used to distinguish between AF and sinus rhythm (SR), this could become a monitoring tool for horses at risk for recurrence of AF. OBJECTIVES: The purpose of this study was to assess whether in horses AF (before cardioversion) and SR (after cardioversion) can be differentiated based upon HRV parameters...
March 21, 2017: Equine Veterinary Journal
https://www.readbyqxmd.com/read/28323136/self-reported-knee-pain-and-disability-among-healthy-individuals-reference-data-and-factors-associated-with-the-knee-injury-and-osteoarthritis-outcome-score-koos-and-koos-child
#5
Jennifer N Baldwin, Marnee J McKay, Claire E Hiller, Niamh Moloney, Elizabeth J Nightingale, Joshua Burns
OBJECTIVE: To develop normative reference data for the Knee injury and Osteoarthritis Outcome Score (KOOS) and KOOS-Child, as well as investigate socio-demographic, psychological and physical factors associated with knee pain and disability among healthy adults. METHOD: The KOOS or KOOS-Child (each containing five subscales) was administered to participants aged 8-101 years within the 1000 Norms Project, an observational study of 1000 self-reported healthy individuals...
March 16, 2017: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/28322035/multidisciplinary-rehabilitation-program-after-breast-cancer-benefits-on-physical-function-anthropometry-and-quality-of-life
#6
Anne-France Leclerc, Marguerite Foidart-Dessalle, Marco Tomasella, Philippe Coucke, Martine Devos, Olivier Bruyère, Thierry Bury, Dorian Deflandre, Guy Jerusalem, Eric Lifrange, Jean-François Kaux, Jean-Michel Crielaard, Didier Maquet
BACKGROUND: Different clinical trials show beneficial effects of physical training offered during and / or after breast cancer treatment. However, given the variety of side effects that may be encountered, physical training could be combined with psychological, relational and social guidance. This kind of multidisciplinary program has been little studied so far. AIM: To determine the benefits of a three-month multidisciplinary rehabilitation program among women after breast cancer treatment...
March 20, 2017: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/28303774/physiological-evaluation-of-personal-protective-ensembles-recommended-for-use-in-west-africa
#7
Aitor Coca, Tyler Quinn, Jung-Hyun Kim, Tianzhou Wu, Jeff Powell, Raymond Roberge, Ronald Shaffer
OBJECTIVE: Personal protective equipment (PPE) provides health care workers with a barrier to prevent human contact with viruses like Ebola and potential transmission of the disease. However, PPE can also introduce an additional physiological burden from potentially increased heat stress. This study evaluated the human physiological and subjective responses to continuous light exercise within environmental conditions similar to those in West Africa while wearing 3 different, commonly used PPE ensembles (E1, E2, and E3)...
March 17, 2017: Disaster Medicine and Public Health Preparedness
https://www.readbyqxmd.com/read/28303772/physiological-evaluation-of-cooling-devices-in-conjunction-with-personal-protective-ensembles-recommended-for-use-in-west-africa
#8
Tyler Quinn, Jung-Hyun Kim, Amanda Strauch, Tianzhou Wu, Jeffery Powell, Raymond Roberge, Ronald Shaffer, Aitor Coca
OBJECTIVE: Cooling devices (CDs) worn under personal protective equipment (PPE) can alleviate some of the heat stress faced by health care workers responding to the Ebola outbreak in West Africa. METHODS: Six healthy, young individuals were tested while wearing 4 different CDs or no cooling (control) under PPE in an environmental chamber (32°C/92% relative humidity) while walking (3 METs, 2.5 mph, 0% grade) on a treadmill for 60 minutes. Exercise was preceded by a 15-minute stabilization period and a 15-minute donning period...
March 17, 2017: Disaster Medicine and Public Health Preparedness
https://www.readbyqxmd.com/read/28294875/-efficiency-of-operation-trombendarterektomy-from-pulmonary-artery-branches-depending-on-the-degree-of-pulmonary-hypertension-and-duration-of-disease
#9
A M Chernyavskiy, A G Edemskiy, M A Chernyavskiy, V G Efimenko, A R Tarkova, S N Ivanov
AIM: to assess effect of thromboendarterectomy from pulmonary artery branches on clinical functional state of patients with chronic thromboembolic pulmonary hypertension (CTEPH) in dependence on degree of pulmonary hypertension and disease duration. MATERIAL: Patients (n=152) were divided into 3 groups: (1) with systolic pulmonary artery pressure (SPAP) less or equal 50 mm Hg (n=20), (2) with SPAP>50- less or equal 80mm Hg (n=46), (3) with SPAP >80mm Hg (n=86)...
May 2016: Kardiologiia
https://www.readbyqxmd.com/read/28280889/end-points-in-heart-failure-are-we-doing-it-right
#10
REVIEW
Luxitaa Goenka, Melvin George, Sandhiya Selvarajan
PURPOSE: Heart Failure (HF) continues to be associated with high mortality and morbidity. We attempted to identify the most common end points used in phase 3 clinical trials of heart failure and discuss their merits and demerits. METHODS: Literature evaluation was done using the databases PubMed and Clinicaltrials.gov from January 2010 to December 2016 to identify randomised clinical trials (RCTs) evaluating the effect of therapeutic drugs on heart failure. Following the literature search, the data on the primary end points were extracted from each of the selected trials...
March 9, 2017: European Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/28278064/fluid-replacement-advice-during-work-in-fully-encapsulated-impermeable-chemical-protective-suits
#11
Candace D Rubenstein, Emiel A DenHartog, A Shawn Deaton, Niels Bogerd, Saskia DeKant
A major concern for responders to hazardous materials (HazMat) incidents is the heat strain that is caused by fully encapsulated impermeable chemical protective suits. In a research project, funded by the US Department of Defense, the thermal strain experienced when wearing these suits was studied. One particular area of interest was the fluid loss of responders during work in these suits as dehydration may be an additional health concern to the heat strain. 17 City of Raleigh firemen and 24 students were tested at two different labs...
February 28, 2017: Journal of Occupational and Environmental Hygiene
https://www.readbyqxmd.com/read/28270192/epidemiology-and-disease-characteristics-of-systemic-sclerosis-related-pulmonary-arterial-hypertension-results-from-a-real-life-screening-programme
#12
Kathleen Morrisroe, Wendy Stevens, Joanne Sahhar, Candice Rabusa, Mandana Nikpour, Susanna Proudman
BACKGROUND: Pulmonary arterial hypertension (PAH) is the leading cause of death in systemic sclerosis (SSc). Annual screening with echocardiogram (ECHO) is recommended. We present the methodological aspects of a PAH screening programme in a large Australian SSc cohort, the epidemiology of SSc-PAH in this cohort, and an evaluation of factors influencing physician adherence to PAH screening guidelines. METHODS: Patient characteristics and results of PAH screening were determined in all patients enrolled in a SSc longitudinal cohort study...
March 7, 2017: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/28269381/relationship-between-gait-variables-and-domains-of-neurologic-dysfunction-in-multiple-sclerosis-using-six-minute-walk-test
#13
Asma Qureshi, Maite Brandt-Pearce, Myla D Goldman
Most multiple sclerosis (MS) patients eventually suffer from mobility impairment, and thus it is critical that walking disability in MS be accurately assessed. The six-minute walk test (6MWT), a reliable MS measure, is traditionally used to determine the distance covered in six minutes using a standard protocol. With the availability of body sensor networks (BSNs), researchers are interested in leveraging BSN data for finding new gait assessment anchors for improved separability performance. Further, current methods for gait assessments are insufficient since assessments are absolute, performed by comparing outcomes to the statistical norms established from diverse patient data despite natural inter-patient variability...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28265169/effect-of-inspiratory-muscle-training-on-respiratory-capacity-and-walking-ability-with-subacute-stroke-patients-a-randomized-controlled-pilot-trial
#14
Kyeong-Man Jung, Dae-Hyouk Bang
[Purpose] To investigate the effects of inspiratory muscle training on respiratory capacity and walking ability in subacute stroke patients. [Subjects and Methods] The subjects were randomly assigned to an experimental group (n=6) or a control group (n=6). Patients in the experimental group received inspiratory muscle training for 30 minutes (six sets of five-minutes) and traditional physical therapy once a day, five days a week, for four weeks. The control group received aerobic exercise for 30 minutes and traditional physical therapy for 30 minutes a day, five days a week, for four weeks...
February 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28244013/impact-of-airflow-limitation-in-chronic-heart-failure
#15
S Bektas, F M E Franssen, V van Empel, N Uszko-Lencer, J Boyne, C Knackstedt, H P Brunner-La Rocca
BACKGROUND: Comorbidities are common in chronic heart failure (HF) patients, but diagnoses are often not based on objective testing. Chronic obstructive pulmonary disease (COPD) is an important comorbidity and often neglected because of shared symptoms and risk factors. Precise prevalence and consequences are not well known. Therefore, we investigated prevalence, pulmonary treatment, symptoms and quality of life (QOL) of COPD in patients with chronic HF. METHODS: 205 patients with stable HF for at least 1 month, aged above 50 years, were included from our outpatient cardiology clinic, irrespective of left ventricular ejection fraction...
February 27, 2017: Netherlands Heart Journal
https://www.readbyqxmd.com/read/28241384/quantitative-muscle-ultrasound-detects-disease-progression-in-duchenne-muscular-dystrophy
#16
Craig M Zaidman, Jim S Wu, Kush Kapur, Amy Pasternak, Lavanya Madabusi, Sung Yim, Adam Pacheck, Heather Szelag, Tim Harrington, Basil T Darras, Seward B Rutkove
OBJECTIVE: We assessed changes in quantitative muscle ultrasound data in boys with Duchenne muscular dystrophy (DMD) and healthy controls to determine if ultrasound can serve as a biomarker of disease progression. Two approaches were used: grey scale level (GSL), measured from the ultrasound image, and quantitative backscatter analysis (QBA) measured directly from the received echoes. METHODS: GSL and QBA were obtained from six unilateral arm/leg muscles in 36 boys with DMD and 28 healthy boys (age 2-14 years) for up to 2 years...
February 27, 2017: Annals of Neurology
https://www.readbyqxmd.com/read/28239753/six-minute-walk-test-in-evaluation-of-children-with-pulmonary-arterial-hypertension
#17
Malgorzata Zuk, Anna Migdal, Dorota Jagiellowicz-Kowalska, Katarzyna Mazurkiewicz, Anna Sadel-Wieczorek, Grazyna Brzezinska-Rajszys
Six-minute walk test (6MWT) is a submaximal exercise test applied for evaluation of adults with pulmonary arterial hypertension (PAH). It was widely used as an endpoint in the clinical trials. The aim of the study was to assess the usefulness of 6MWT in management of children with PAH and to establish correlations with other clinical features. 164 6MWT were performed in 15 children between 5 and 18 years with PAH confirmed by right heart catheterization (102 in patients with shunt, 62 without shunt). Distance in 6MWT (6MWD)-% of predicted for age and gender, desaturation at the maximum effort, peak heart rate (HR)-% of maximal HR, were compared to the level of NTproBNP, WHO-FC, echocardiography parameters, and events of PAH treatment intensification...
February 27, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/28237536/early-experience-of-macitentan-for-pulmonary-arterial-hypertension-in-adult-congenital-heart-disease
#18
S Herbert, W Gin-Sing, L Howard, R M R Tulloh
BACKGROUND: Endothelin receptor antagonists (ERA) have been recognised as effective therapy for pulmonary arterial hypertension in congenital heart disease (CHD-PH), and Eisenmenger syndrome (ES) since the Breathe 5 study. A new dual receptor antagonist - Macitentan - is currently undergoing trials to determine its efficacy in simple ES. To date there is little information on this therapy in CHD and we report our first experience, some with more complex diseases. METHODS: Data was collected prospectively from September 2014...
February 6, 2017: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/28229829/six-minute-walk-test-in-or-out-in-evaluation-of-systemic-sclerosis-patients
#19
Els Vandecasteele, Kristof Thevissen, Karin Melsens, Filip De Keyser, Michel De Pauw, Ellen Deschepper, Saskia Decuman, Yves Piette, Guy Brusselle, Vanessa Smith
OBJECTIVES: Interstitial lung disease (ILD) and pulmonary arterial hypertension (PAH) are the leading causes of death in systemic sclerosis (SSc) patients. Although the six-minute walk test (6MWT) is used for evaluating ILD and PAH in clinical practice, no data are available on six-minute walk distance (6MWD) and oxygen desaturation in SSc patients without ILD and PAH. METHODS: Prospectively collected data of the 6MWTs at baseline and 6-month follow-up of 300 consecutive SSc patients, included in the Ghent University Hospital Systemic Sclerosis Unit between May 2006 and April 2015 were analysed...
February 15, 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/28227624/relationship-between-gait-variables-and-domains-of-neurologic-dysfunction-in-multiple-sclerosis-using-six-minute-walk-test
#20
Asma Qureshi, Maite Brandt-Pearce, Myla D Goldman, Asma Qureshi, Maite Brandt-Pearce, Myla D Goldman, Asma Qureshi, Myla D Goldman, Maite Brandt-Pearce
Most multiple sclerosis (MS) patients eventually suffer from mobility impairment, and thus it is critical that walking disability in MS be accurately assessed. The six-minute walk test (6MWT), a reliable MS measure, is traditionally used to determine the distance covered in six minutes using a standard protocol. With the availability of body sensor networks (BSNs), researchers are interested in leveraging BSN data for finding new gait assessment anchors for improved separability performance. Further, current methods for gait assessments are insufficient since assessments are absolute, performed by comparing outcomes to the statistical norms established from diverse patient data despite natural inter-patient variability...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
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