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Six minutes walk test

Daniel L Riddle, Mark P Jensen, Dennis Ang, James Slover, Robert Perera, Levent Dumenci
BACKGROUND: Pain-coping strategies and appraisals are responses to the pain experience. They can influence patient-reported and physical performance outcome measures in a variety of disorders, but the associations between a comprehensive profile of pain-coping responses and preoperative pain/function and physical performance measures in patients scheduled for knee arthroplasty have not been examined. Patients with moderate to high pain catastrophizing (a pain appraisal approach associated with an exaggerated focus on the threat value of pain) may represent an excellent study population in which to address this knowledge gap...
April 2018: Clinical Orthopaedics and related Research
Ali J Marian, Yanli Tan, Lili Li, Jeffrey T Chang, Petros Syrris, Manouchehr Hessabi, Mohammad H Rahbar, James T Willerson, Benjamin Y Cheong, Chia-Ying Liu, Neal S Kleiman, David A Bluemke, Sherif F Nagueh
<u>Rationale:</u> Hypertrophic cardiomyopathy (HCM) is a genetic paradigm of cardiac hypertrophy. Cardiac hypertrophy and interstitial fibrosis are important risk factors for sudden death and morbidity in HCM. Oxidative stress is implicated in the pathogenesis of cardiac hypertrophy and fibrosis. Treatment with anti-oxidant N-acetylcysteine (NAC) reverses cardiac hypertrophy and fibrosis in animal models of HCM. <u>Objective:</u> To determine effect sizes of NAC on indices of cardiac hypertrophy and fibrosis in patients with established HCM...
March 14, 2018: Circulation Research
Patrick J Smith, Rebecca Byrd, Megan Lusby, Emily Clausen, Laurie D Snyder
BACKGROUND: Depressive symptoms are common among lung transplant recipients and have been associated with worse clinical outcomes. However, few studies have examined the association between depressive symptoms assessed at multiple time points or behavioral mechanisms by which post-transplant depressive symptoms may confer greater clinical risk. We therefore examined the associations between depressive symptoms, exercise capacity, chronic lung allograft dysfunction (CLAD), and mortality prospectively in a large sample of lung transplant recipients...
March 12, 2018: Psychosomatic Medicine
Jacqueline C Outermans, Ingrid van de Port, Gert Kwakkel, Johanna M Visser-Meily, Harriet Wittink
BACKGROUND: Reports on the association between aerobic capacity and walking capacity in people after stroke show disparate results. AIM: To determine (1) if the predictive validity of peak oxygen uptake (VO2peak) for walking capacity post stroke is different from that of maximal oxygen uptake (VO2max) and (2) if postural control, hemiplegic lower extremity muscle strength, age and gender distort the association between aerobic capacity and walking capacity. DESIGN: Cross-sectional study...
March 12, 2018: European Journal of Physical and Rehabilitation Medicine
Ralph A H Stewart, Dominika Szalewska, Amanda Stebbins, Hussein R Al-Khalidi, John G H Cleland, Andrzej Rynkiewicz, Mark H Drazner, Harvey D White, Daniel B Mark, Ambuj Roy, Dragana Kosevic, Miroslaw Rajda, Marek Jasinski, Chua Yeow Leng, Wiwun Tungsubutra, Patrice Desvigne-Nickens, Eric J Velazquez, Mark C Petrie
Background: In patients with ischaemic left ventricular dysfunction, coronary artery bypass surgery (CABG) may decrease mortality, but it is not known whether CABG improves functional capacity. Objective: To determine whether CABG compared with medical therapy alone (MED) increases 6 min walk distance in patients with ischaemic left ventricular dysfunction and coronary artery disease amenable to revascularisation. Methods: The Surgical Treatment in Ischemic Heart disease trial randomised 1212 patients with ischaemic left ventricular dysfunction to CABG or MED...
2018: Open Heart
Semra Aktürk, Raikan Büyükavcı, Yüksel Ersoy
OBJECTIVE: The aim of this study is to identify the effect on spasticity and walking of US-guided botulinum toxin type A (BoNT-A) injections administered to improve equinovarus walking pattern commonly observed in patients after stroke. MATERIAL AND METHOD: Twenty-three patients with post-stroke spastic equinovarus deformity were recruited. The US-guided BoNT-A injections were administered into the spastic muscles (including gastrocnemius; GK, soleus; S and tibialis posterior; TP) using a specific approach, and all of the patients were enrolled in rehabilitation programmes after the injections...
March 9, 2018: Toxicon: Official Journal of the International Society on Toxinology
Megan Knox, Aimee Stewart, Carol L Richards
OBJECTIVE: To evaluate a minimal dose intervention of six 1-hour sessions of task-oriented circuit gait training including a caregiver over a 12-week period to persons post stroke in the South African public health sector. DESIGN: Stratified, single blinded, randomized controlled trial with three intervention groups. PARTICIPANTS: Persons post stroke ( n = 144, mean age 50 years, 72 women), mean 9.5 weeks post stroke. INTERVENTIONS: Task group ( n = 51)-accompanied by a caregiver; task-oriented circuit gait training (to improve strength, balance, and task performance while standing and walking)...
March 1, 2018: Clinical Rehabilitation
Samuel T Orange, Phil Marshall, Leigh A Madden, Rebecca V Vince
This study compared the effects of a 4-week supervised (SUP) and unsupervised (UNSUP) resistance training programme followed by 12 weeks of detraining (DET). Thirty-six healthy aging adults (age: 53.6 ± 3.6 years; body mass index: 28.3 ± 5.1 kg/m) were randomly allocated to a SUP group (n = 17) or an UNSUP group (n = 19). Participants completed three training sessions per week using resistance bands and body weight movements. Measures of physical performance were administered at baseline, at the end of the training programme, and after the DET period...
March 6, 2018: Journal of Strength and Conditioning Research
Edward P Washabaugh, Chandramouli Krishnan
BACKGROUND: Robotic-resisted treadmill walking is a form of task-specific training that has been used to improve gait function in individuals with neurological injury, such as stroke, spinal cord injury, or cerebral palsy. Traditionally, these devices use active elements (e.g., motors or actuators) to provide resistance during walking, making them bulky, expensive, and less suitable for overground or in-home rehabilitation. We recently developed a low-cost, wearable robotic brace that generates resistive torques across the knee joint using a simple magnetic brake...
2018: Restorative Neurology and Neuroscience
Ji Yan, Shu Zhang, Dejia Huang, Xiaolin Xue, Jing Xu, Qianmin Tao, Weize Zhang, Zheng Zhang, Wei Hua, Yanchun Liang, Baopeng Tang, Wei Xu, Geng Xu, Xuejun Ren, Jingfeng Wang, Tao Guo, Shaobin Jia, Yugang Dong, Hong Jiang, Guosheng Fu, Liguang Zhu, Lin Chen, Fuli Tian, Feng Ling, Jianmei Li, Xiaoyong Qi, Yinglu Hao, Yutang Wang, Liangrong Zheng, Xiaoqun Pu, Farong Shen, Guangping Li, Hui Li, Fang Peng
In this trial, long-term therapeutic effects and clinical improvements in Chinese chronic heart failure patients optimized by QuickOpt or echocardiography were compared for atrioventricular (AV) and interventricular (VV) delay optimizations after cardiac resynchronization therapy (CRT) with pacing (CRT-P) or with pacing and defibrillator (CRT-D) therapy. One hundred and ninety-six subjects (50%) had dilated cardiomyopathy, 108 (27.6%) had ischemic heart disease and 112 (28.6%) were hypertensive and were randomized into QuickOpt (198) or echocardiographic optimization (control) (194) groups at ≤2-weeks post-implantation...
March 9, 2018: Scientific Reports
Gabriele Mascherini, Benedetta Tosi, Chiara Giannelli, Elisabetta Grifoni, Sonia Degl'innocenti, Giorgio Galanti
BACKGROUND: Improvements in prevention and therapeutic strategies over the years have increased the numbers of breast cancer survivors considerably. Sedentary behavior is now acknowledged to be a risk factor for cancer and cancer relapse. Currently, there are different approaches to increasing the effectiveness of long-term physical activity in these patients. The aim of this study was to verify the long-term effectiveness of a home-based program for active lifestyle change in overweight breast cancer survivors...
March 1, 2018: Journal of Sports Medicine and Physical Fitness
Arda Kiani, Tahereh Parsa, Parisa Adimi Naghan, Hervé Dutau, Fatemeh Razavi, Behrooz Farzanegan, Mahsa Pourabdollah Tootkaboni, Atefeh Abedini
INTRODUCTION: Pulmonary alveolar proteinosis (PAP) is a rare disease in the field of pulmonary medicine. The efficacy of whole-lung lavage (WLL) as the treatment of PAP had never been evaluated in the Iranian population. Therefore, there is a real need to investigate the characteristics of PAP and also to evaluate the efficacy of WLL in this rare disease. The study aimed to investigate demographic features, clinical presentation and treatment outcomes of the disease in Iranian PAP patients...
2018: Advances in Respiratory Medicine
Christina Titz, Simone Hummler, Martina E Schmidt, Michael Thomas, Martin Steins, Joachim Wiskemann
PURPOSE: The aim of this work was to evaluate exercise behavior and physical fitness of advanced lung cancer patients shortly after primary diagnosis. METHODS: Between November 2013 and December 2016, advanced lung cancer patients (n = 227, mean age 62.2 years) were enrolled shortly after diagnosis and 211 patients were tested for endurance capacity (six-minute walk test) and strength performance (maximum voluntary isometric contraction of upper and lower extremities)...
February 26, 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
Paola Ortelli, Davide Ferrazzoli, Rossana Bera, Luca Caremani, Nir Giladi, Roberto Maestri, Giuseppe Frazzitta
BACKGROUND: Parkinsonian patients in advanced stages of disease suffer from many motor and non-motor symptoms, whose responsiveness to dopamine replacement therapy and deep brain stimulation is poor. It is necessary to find complementary strategies in order to improve the clinical conditions of patients in advanced Parkinson's disease (PD) stages. OBJECTIVE: We aimed to understand whether an inpatient, motor-cognitive, multidisciplinary, aerobic, intensive and goal-based rehabilitation treatment (MIRT), specifically designed for PD, is effective for patients in advanced stages of disease...
2018: Journal of Parkinson's Disease
Mansueto Gomes Neto, Filipe Ferrari Ribeiro de Lacerda, Antonio Alberto Lopes, Bruno Prata Martinez, Micheli Bernardone Saquetto
OBJECTIVE: To determine the effects of different intradialytic exercise training modalities on physical functioning and health-related quality of life of maintenance hemodialysis patients. METHODS: We searched MEDLINE, Cochrane Trials Register and CINAHL for controlled trials that evaluated the effects of intradialytic exercise training for maintenance hemodialysis patients and published from the earliest available date to December 2017. Weighted mean difference and 95% confidence interval (CI) were calculated, and heterogeneity was assessed using the I2 test...
February 1, 2018: Clinical Rehabilitation
Emmanuel Bonney, Eugene Rameckers, Gillian Ferguson, Bouwien Smits-Engelsman
BACKGROUND: Adolescents with low motor competence participate less in physical activity and tend to exhibit decreased physical fitness compared to their peers with high motor competence. It is therefore essential to identify new methods of enhancing physical fitness in this population. Active video games (AVG) have been shown to improve motor performance, yet investigations of its impact on physical fitness are limited. The objective of this study was to examine the impact of the graded Wii protocol in adolescent girls with probable Developmental Coordination Disorder (p-DCD)...
February 22, 2018: BMC Pediatrics
Kellie Toohey, Kate Pumpa, Andrew McKune, Julie Cooke, Katrina D DuBose, Desmond Yip, Paul Craft, Stuart Semple
AIM: To determine the impact of low volume high-intensity interval training (LVHIIT) and continuous low to moderate-intensity exercise training (CLMIT) on cardiovascular disease (CVD) risk and health outcomes in cancer survivors. METHODS: Sedentary cancer survivors ( n = 75, aged 51 ± 12 year) within 24 months of diagnosis, were randomised into three groups for 12 wk of LVHIIT ( n = 25), CLMIT ( n = 25) or control group ( n = 25). The exercise intervention involved 36 sessions (three sessions per week)...
February 10, 2018: World Journal of Clinical Oncology
Kristoffer Ostridge, Nicholas P Williams, Viktoriya Kim, Stephen Harden, Simon Bourne, Stuart C Clarke, Emmanuel Aris, Sonia Mesia-Vela, Jeanne-Marie Devaster, Andrew Tuck, Anthony Williams, Stephen Wootton, Karl J Staples, Tom M A Wilkinson
BACKGROUND: COPD is a complex, heterogeneous disease characterised by progressive development of airflow limitation. Spirometry provides little information about key aspects of pathology and is poorly related to clinical outcome, so other tools are required to investigate the disease. We sought to explore the relationships between quantitative CT analysis with functional, inflammatory and infective assessments of disease to identify the utility of imaging to stratify disease to better predict outcomes and disease response...
February 20, 2018: Respiratory Research
Tristan Bonnevie, Francis-Edouard Gravier, David Debeaumont, Catherine Viacroze, Jean-François Muir, Antoine Cuvelier, Marie Netchitaïlo, Anne Laure Roy, Jean Quieffin, Marie-Hélène Marques, Clément Médrinal, Johan Dupuis, Catherine Tardif
OBJECTIVE: To assess the additional effect of a home-based neuro muscular electrical stimulation (NMES) program as an add-on to pulmonary rehabilitation (PR), on functional capacity in subjects with chronic obstructive pulmonary disease (COPD). DESIGN: Single-blind, multicenter randomized trial. SETTING: Three PR centers. PARTICIPANTS: Subjects with severe to very severe COPD referred for PR (n=73; median FEV1, 1 (0...
February 16, 2018: Archives of Physical Medicine and Rehabilitation
Akmer Mutlu, Halil Alkan, Tuzun Fırat, Aynur A Karaduman, Oznur T Yilmaz
OBJECTIVE: To compare the fatigue levels and energy expenditure of children with Duchenne Muscular Dystrophy (DMD) at different functional levels with healthy children. METHODS: The cross-sectional study was carried out in the Unit of Pediatric Neuromuscular Diseases in the Department of Physiotherapy and Rehabilitation, Faculty of Health Science, Hacettepe University between March 2015 and January 2016. Fifty two children diagnosed with DMD in Level I-III according to the Brooke Functional Classification Scale and 17 healthy children were included in the study...
January 2018: Neurosciences: the Official Journal of the Pan Arab Union of Neurological Sciences
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