keyword
MENU ▼
Read by QxMD icon Read
search

Laryngomalacia

keyword
https://www.readbyqxmd.com/read/27919989/teratogenic-effect-of-radotinib-case-report
#1
Juyoung Cheon, Jung Whan Ahn, Kyung Min Park, Guisera Lee, Yun Sung Jo
BACKGROUND: Simultaneous presentation of pregnancy and chronic myeloid leukemia (CML) is rare. Tyrosine kinase inhibitors (TKIs) are rarely used in pregnancy. There is almost no information on the effect of recently developed TKIs on the fetus. CASE REPORT: A 22-year-old woman became pregnant while using radotinib, a novel TKI for CML. She was concerned about the possible teratogenic effect of radotinib; hence the first pregnancy was terminated. The patient underwent full-term delivery at the second pregnancy...
December 2016: Anticancer Research
https://www.readbyqxmd.com/read/27872941/-supraglottoplasty-for-pediatric-laryngomalacia-results-from-71-cases
#2
D Di Dio, P Amrhein, A Koitschev, C Sittel
Laryngomalacia is the most common cause of stridor in infants. The stridor is caused by an inward collapse of supraglottic structures during inspiration resulting in an inspiratory stridor. The exact etiology still remains unclear. The surgical procedure of choice for laryngomalacia is supraglottoplasty. From 2009 to 2016 a total of 71 children were treated by supraglottoplasty in the department for pediatric otorhinolaryngology of the Stuttgart Hospital. The indications for supraglottoplasty were laryngomalacia with severe inspiratory stridor, oxygen desaturation, suprasternal or chest retraction, feeding difficulties and/or failure to thrive...
December 2016: HNO
https://www.readbyqxmd.com/read/27792854/camptodactyly-and-the-22q11-2-deletion-syndrome
#3
Natario L Couser, Chetna K Pande, Jonathan M Walsh, James Tepperberg, Arthur S Aylsworth
We describe a 5-day-old male with minor facial anomalies, a congenital laryngeal web, severe laryngomalacia, and prominent fixed flexion of the proximal interphalangeal joints of digits 2 through 5 bilaterally. A whole genome SNP microarray analysis identified a 2.55 Mb interstitial deletion of 22q11.21, typical of that seen in the DiGeorge and Velocardiofacial syndromes. A review of the literature identifies 10 other cases with camptodactyly. Camptodactyly appears to be an associated but rarely reported anomaly in patients with the 22q11...
October 28, 2016: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/27722899/types-of-laryngomalacia-in-children-interrelationship-between-clinical-course-and-comorbid-conditions
#4
Beata Kusak, Ewa Cichocka-Jarosz, Urszula Jedynak-Wasowicz, Grzegorz Lis
The aim of this study was to: (1) find out whether laryngomalacia (LM) types are related to clinical course; (2) which patients with LM are at higher risk of other airway malacia [tracheomalacia (TM) and/or bronchomalacia (BM)]; and (3) evaluate the prevalence of LM in our region. Patients with established LM diagnosis and complete clinical and endoscopy records were enrolled. They were classified into different LM types according to classification based on the side of supraglottic obstruction. One hundred ten children were included...
October 8, 2016: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/27696664/a-say-barber-biesecker-young-simpson-variant-of-ohdo-syndrome-with-a-kat6b-10-base-pair-palindromic-duplication-a-recurrent-mutation-causing-a-severe-phenotype-mixed-with-genitopatellar-syndrome
#5
Yo Niida, Yusuke Mitani, Mondo Kuroda, Ayano Yokoi, Hiroyasu Nakagawa, Akiko Kato
The Say-Barber-Biesecker-Young-Simpson variant of Ohdo syndrome (SBBYSS) (MIM# 603736) and genitopatellar syndrome (GPS) (MIM#606170) are allelic diseases caused by KAT6B mutation. Genotype-phenotype correlation is assumed, but a few patients manifest overlapping features of both syndromes. Here we report the case of a boy with SBBYSS. He had a KAT6B mutation previously reported in typical SBBYSS, but he also manifested severe developmental delay, as well as genital features and laryngomalacia requiring tracheostomy that conformed to GPS...
October 3, 2016: Congenital Anomalies
https://www.readbyqxmd.com/read/27636982/beyond-dilation-current-concepts-in-endoscopic-airway-stenting-and-reconstruction
#6
Sharon H Gnagi, David R White
PURPOSE OF REVIEW: To discuss current modalities of endoscopic airway management beyond balloon dilation therapy. RECENT FINDINGS: Advances continue to be made through technology and bioengineering with exciting potential in the pediatric airway. Smaller robots and instrumentation allow increased endoscopic surgical success. Biodegradable stents and bioengineered grafts are on the horizon for use in airway surgery. Dysphonia following airway reconstruction is of increasing recognition with new endoscopic treatments being performed...
December 2016: Current Opinion in Otolaryngology & Head and Neck Surgery
https://www.readbyqxmd.com/read/27522662/laser-supraglottoplasty-for-laryngomalacia-a-14%C3%A2-year-experience-of-a-tertiary-referral-center
#7
Antoine Reinhard, François Gorostidi, Crispin Leishman, Philippe Monnier, Kishore Sandu
To review the outcomes of laser supraglottoplasty performed in children with symptomatic laryngomalacia and determine the factors influencing them. We retrospectively reviewed the medical records of patients who underwent laser supraglottoplasty for symptomatic laryngomalacia at the Lausanne University Hospital from November 2001 to November 2014. We examined the patient's demography, symptoms, comorbidities, type of laryngomalacia, synchronous airway lesions, and final outcomes. Seventy-nine patients were included in this study; median age at the time of surgery was 12...
August 13, 2016: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/27433749/laryngomalacia-with-epiglottic-prolapse-obscuring-the-laryngeal-inlet
#8
Michael Laschat, Jost Kaufmann, Frank Wappler
No abstract text is available yet for this article.
August 2016: Anesthesiology
https://www.readbyqxmd.com/read/27421024/de-novo-interstitial-deletion-in-the-long-arm-of-chromosome-11-a-case-report
#9
L L Li, H G Zhang, X G Shao, J C Gao, H Y Zhang, R Z Liu
The 11q terminal deletion disorder is a rare genetic disorder associated with numerous clinical features. A few case reports have been made about de novo interstitial deletion of chromosome 11q. However, due to the heterogeneity in size and position of the deletions, a clear genotype-phenotype correlation is not easily made. Here we report a case interstitial 20.5-Mb deletion at chromosome 11q13.4q21, as confirmed by array comparative genomic hybridization. Dysmorphic features such as coarse facial features, congenital laryngomalacia, oblique inguinal hernia, high-arched palate, and camptodactyly were observed in the subject...
2016: Genetics and Molecular Research: GMR
https://www.readbyqxmd.com/read/27375399/anesthetic-management-of-vallecular-cyst-excision-in-an-infant-an-airway-challenge
#10
Viraj N Namshikar, Nimisha V Dukle, Dattraj S Sukhthanker
Vallecular cyst is uncommon but well-recognized cause of upper airway obstruction in newborn and infants. We hereby present anesthetic management of a case of vallecular cyst in an infant posted for excision and marsupialization. A 4-month-old female infant weighing 3.5 kg presented with inspiratory stridor progressively worsening over 2 months. Anesthesia plan was to carry out inhalational induction maintaining spontaneous respiration and keeping tracheostomy as standby option. In this case, laryngoscopy was challenging due to the size and extent of the cyst thus necessitating gentle laryngoscopy to prevent cyst rupture and pulmonary aspiration...
July 2016: Saudi Journal of Anaesthesia
https://www.readbyqxmd.com/read/27368449/supraglottoplasty-outcomes-in-children-with-down-syndrome
#11
Cara C Cockerill, Christopher D Frisch, Sarah E Rein, Laura J Orvidas
OBJECTIVE: Children with Down syndrome have a higher incidence of upper airway obstruction and laryngomalacia. We sought to determine outcomes of supraglottoplasty in this patient population. METHODS: A retrospective chart review was performed from January 2000 through January 2014. Children (n = 18) at our institution with the diagnosis of Down syndrome who underwent supraglottoplasty were included. We reviewed patient characteristics, preoperative findings, and surgical outcomes (stridor, feeding problems, respiratory distress, weight, sleep apnea, and tracheostomy or feeding tube dependence)...
August 2016: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/27368437/treatment-outcomes-of-supraglottoplasty-for-pediatric-obstructive-sleep-apnea-a-meta-analysis
#12
REVIEW
Chia-Fan Lee, Wei-Chung Hsu, Chia-Hsuan Lee, Ming-Tzer Lin, Kun-Tai Kang
OBJECTIVE: To comprehensively review changes in sleep parameters and the success rate of supraglottoplasty for treating obstructive sleep apnea (OSA) in children. In particular, to elucidate treatment modalities and factors affecting treatment outcomes in children with both laryngomalacia and OSA. METHODS: The study protocol was registered on PROSPERO (CRD42015027053). Two authors independently searched databases including PubMed, MEDLINE, EMBASE, and the Cochrane Review database...
August 2016: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/27366529/anaesthesia-management-in-a-patient-with-waardenburg-syndrome-and-review-of-the-literature
#13
Kevser Peker, Julide Ergil, İbrahim Öztürk
Waardenburg syndrome is a rare autosomal dominant disease that may cause hearing loss, pigmentary abnormalities, neurocristopathy and partial albinism. Incidence is estimated as 2%-3% among the cases of congenital deafness and 1/42,000 of the general population. Children with Waardenburg syndrome usually require anaesthesia for the cochlear implant operation in early age. The features of the syndrome that may bear importance for anaesthetic management are laryngomalacia, multiple muscle contractures, limited neck movements, cyanotic cardiopathy and electrolyte imbalance...
October 2015: Turkish Journal of Anaesthesiology and Reanimation
https://www.readbyqxmd.com/read/27301595/laryngomalacia
#14
Joshua Bedwell, George Zalzal
Laryngomalacia is the most common cause of stridor in neonates. It typically presents with inspiratory stridor and is often associated with feeding problems. Severe cases present with stridor, apnea, significant respiratory distress, and failure to thrive. Most patients are managed conservatively and can expect to see symptom resolution by 12-24 months of age. About 10% of patients require surgical treatment for their symptoms. Supraglottoplasty is the surgical technique of choice. Results of this surgery are excellent, and severe complications, such as supraglottic stenosis and aspiration, are uncommon...
June 2016: Seminars in Pediatric Surgery
https://www.readbyqxmd.com/read/27261936/topical-lidocaine-does-not-exaggerate-laryngomalacia-in-infants-during-flexible-bronchoscopy-under-propofol-anesthesia
#15
Britta S von Ungern-Sternberg, Daniel Trachsel, Guicheng Zhang, Thomas O Erb, Jürg Hammer
BACKGROUND: Topical lidocaine has been found to result in overestimation of the severity of laryngomalacia in infants undergoing flexible bronchoscopy under conscious sedation with midazolam and nalbuphine. This effect has never been confirmed and may depend on the level of sedation and the drugs used. We assessed the effect of topical lidocaine on laryngomalacia in infants undergoing flexible bronchoscopy under general anesthesia with propofol. METHODS: Thirteen infants with congenital stridor referred to diagnostic flexible video-bronchoscopy were studied under propofol anesthesia before and 3 minutes after topical lidocaine administration to the larynx at a dose of 3 mg/kg body weight...
July 2016: Journal of Bronchology & Interventional Pulmonology
https://www.readbyqxmd.com/read/27260594/practice-patterns-in-supraglottoplasty-and-perioperative-care
#16
Vaibhav H Ramprasad, Marisa A Ryan, Alfredo E Farjat, Rose J Eapen, Eileen M Raynor
OBJECTIVES: Supraglottoplasty is the first-line surgical treatment for severe laryngomalacia. The purpose of this study is to determine the current trends of practice patterns in managing children who require supraglottoplasty. METHODS: A 25-question survey regarding supraglottoplasty techniques and perioperative management was sent by e-mail to 274 physician members of the Society for Ear, Nose and Throat Advances in Children (SENTAC). RESULTS: 101 surgeons responded and 72% of respondents were in academic practice (p < 0...
July 2016: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/27259063/objective-outcomes-of-supraglottoplasty-for-children-with-laryngomalacia-and-obstructive-sleep-apnea-a-meta-analysis
#17
Zachary Farhood, Adrian A Ong, Shaun A Nguyen, M Boyd Gillespie, Christopher M Discolo, David R White
IMPORTANCE: Surgical intervention is the main treatment alternative for patients with severe laryngomalacia. Supraglottoplasty offers effective treatment results not only for laryngomalacia but also for concurrent obstructive sleep apnea (OSA). OBJECTIVE: To quantify the objective outcomes of supraglottoplasty for laryngomalacia with OSA via polysomnography data in the pediatric population. DATA SOURCES: A comprehensive literature search of the PubMed database was performed on May 20, 2015, using the search terms supraglottoplasty, epiglottoplasty, aryepiglottoplasty, laryngomalacia, obstructive sleep apnea, Apnea-Hypopnea Index (AHI), children, and polysomnography...
July 1, 2016: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/27228428/accuracy-of-clinical-swallowing-evaluation-for-diagnosis-of-dysphagia-in-children-with-laryngomalacia-or-glossoptosis
#18
Marisa Gasparin, Cláudia Schweiger, Denise Manica, Antônio Carlos Maciel, Gabriel Kuhl, Deborah Salle Levy, Paulo José Cauduro Marostica
OBJECTIVE: To investigate the accuracy of clinical evaluation of swallowing in a sample of children with laryngomalacia or glossoptosis and describe the prevalence of dysphagia in each of these diseases, as well as characterize the swallow response to speech and language therapy interventions. STUDY DESIGN: Children aged 1 month to 11 years receiving care at the Department of Otolaryngology, Hospital de Clínicas de Porto Alegre, Brazil, were evaluated in a cross-sectional design...
May 26, 2016: Pediatric Pulmonology
https://www.readbyqxmd.com/read/27114819/rarely-seen-nasal-congenital-problems-causing-neonatal-upper-respiratory-obstruction-a-case-series
#19
Yeşim Başal, Abdullah Bariş Akcan, Yasemin Durum Polat, Ceren Günel, Aylin Eryilmaz, Sema Başak
Since newborns are obligatory nasal breathers, upper respiratory tract problems may sometimes be life threatening. The most common pathology causing dyspnea and stridor in newborns is laryngomalacia. Nasal cavity pathologies that risk the neonatal airway are more rarely met. These anomalies may be seen either as solitary anomalies or as a part of a syndrome. While choanal atresia is one of the best-known nasal cavity anomalies, choanal stenosis, congenital nasal mid-line masses, congenital nasal pyriform aperture stenosis, and nasal tip anomalies are more rarely seen structural pathologies...
March 31, 2016: Pediatric Reports
https://www.readbyqxmd.com/read/27107728/international-pediatric-orl-group-ipog-laryngomalacia-consensus-recommendations
#20
REVIEW
John Carter, Reza Rahbar, Matthew Brigger, Kenny Chan, Alan Cheng, Sam J Daniel, Alessandro De Alarcon, Noel Garabedian, Catherine Hart, Christopher Hartnick, Ian Jacobs, Bryan Liming, Richard Nicollas, Seth Pransky, Gresham Richter, John Russell, Michael J Rutter, Anne Schilder, Richard J H Smith, Julie Strychowsky, Robert Ward, Karen Watters, Michelle Wyatt, George Zalzal, Karen Zur, Dana Thompson
OBJECTIVE: To provide recommendations for the comprehensive management of young infants who present with signs or symptoms concerning for laryngomalacia. METHODS: Expert opinion by the members of the International Pediatric Otolaryngology Group (IPOG). RESULTS: Consensus recommendations include initial care and triage recommendations for health care providers who commonly evaluate young infants with noisy breathing. The consensus statement also provides comprehensive care recommendations for otolaryngologists who manage young infants with laryngomalacia including: evaluation and treatment considerations for commonly debated issues in laryngomalacia, initial work-up of infants presenting with inspiratory stridor, treatment recommendations based on disease severity, management of the infant with feeding difficulties, post-surgical treatment management recommendations, and suggestions for acid suppression therapy...
July 2016: International Journal of Pediatric Otorhinolaryngology
keyword
keyword
40128
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"